MetaADEDB 2.0 @ LMMD
Lactose Intolerance
(UMLS:C0022951)
Definition:
The condition resulting from the absence or deficiency of LACTASE in the MUCOSA cells of the GASTROINTESTINAL TRACT, and the inability to break down LACTOSE in milk for ABSORPTION. Bacterial fermentation of the unabsorbed lactose leads to symptoms that range from a mild indigestion (DYSPEPSIA) to severe DIARRHEA. Lactose intolerance may be an inborn error or acquired.
UMLS ID:
C0022951
MeSH ID:
D007787
Classification 1:
Name:
Digestive System Diseases
MeSH Tree Number(s):
C06.405.469.637.506
Classification 2:
Name:
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):
C16.320.565.202.589
Classification 3:
Name:
Nutritional and Metabolic Diseases
MeSH Tree Number(s):
C18.452.603.506|C18.452.648.202.589
Synonym(s)
1.
Lactose Intolerance
2.
Cows milk enteropathy
3.
Dairy product intolerance
4.
INTOLERANCE LACTOSE
5.
Intolerance to lactose
6.
Intolerance;lactose
7.
LACTOSE INTOLERANCE
8.
LM - Lactose malabsorption
9.
Lactose intolerance
10.
Lactose intolerance, unspecified
11.
Lactose malabsorption
12.
MILK INTOLERANCE
13.
MILK SUGAR INTOLERANCE
14.
Milk intolerance
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1LenalidomideFAERS: 32US FAERS
2AlendronateFAERS: 22US FAERS
3FinasterideFAERS: 16US FAERS
4OctreotideFAERS: 16US FAERS
5ThyroxineFAERS: 16US FAERS
6TeriparatideFAERS: 10US FAERS
7apixabanFAERS: 10US FAERS
8PregabalinFAERS: 9US FAERS
9BudesonideFAERS: 8US FAERS
10CelecoxibFAERS: 8
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
11IsotretinoinFAERS: 8US FAERS
12Olmesartan MedoxomilFAERS: 8US FAERS
13Rosuvastatin CalciumFAERS: 8US FAERS
14ThyroxineFAERS: 8US FAERS
15Zoledronic AcidFAERS: 8
Canada Vigilance: 1		Canada Vigilance
US FAERS
16AtorvastatinFAERS: 7US FAERS
17GabapentinFAERS: 7US FAERS
18Benicar hctFAERS: 6US FAERS
19Dimethyl FumarateFAERS: 6US FAERS
20Fingolimod HydrochlorideFAERS: 6US FAERS
21NuvaRingFAERS: 6US FAERS
224-AminopyridineFAERS: 5US FAERS
23ClonazepamFAERS: 5US FAERS
24PhenytoinFAERS: 5US FAERS
25RisperidoneFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
26apremilastFAERS: 5US FAERS
27fexofenadineFAERS: 5US FAERS
284-hydroxybutyric acidFAERS: 4US FAERS
29AmoxicillinFAERS: 4US FAERS
30EsomeprazoleFAERS: 4US FAERS
31MethylphenidateFAERS: 4US FAERS
32NorgestrelFAERS: 4
Canada Vigilance: 3		Canada Vigilance
US FAERS
33OmeprazoleFAERS: 4US FAERS
34Quetiapine FumarateFAERS: 4US FAERS
35Raloxifene HydrochlorideFAERS: 4US FAERS
36SertralineFAERS: 4US FAERS
37Tiotropium BromideFAERS: 4US FAERS
38TopiramateFAERS: 4US FAERS
39AlprazolamFAERS: 3US FAERS
40AzithromycinFAERS: 3US FAERS
41DasatinibFAERS: 3US FAERS
42DeferasiroxFAERS: 3OFFSIDES
US FAERS
43DiclofenacFAERS: 3US FAERS
44Duloxetine HydrochlorideFAERS: 3US FAERS
45LiraglutideFAERS: 3US FAERS
46LoperamideFAERS: 3US FAERS
47MirtazapineFAERS: 3US FAERS
48OctreotideFAERS: 3OFFSIDES
US FAERS
49OndansetronFAERS: 3US FAERS
50Sitagliptin PhosphateFAERS: 3US FAERS
51WarfarinFAERS: 3US FAERS
52WarfarinFAERS: 3US FAERS
53rofecoxibFAERS: 3OFFSIDES
US FAERS
544-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamideFAERS: 2US FAERS
55AnastrozoleFAERS: 2OFFSIDES
US FAERS
56Atomoxetine HydrochlorideFAERS: 2US FAERS
57BuprenorphineFAERS: 2US FAERS
58CID 129626832FAERS: 2US FAERS
59CefdinirFAERS: 2US FAERS
60CitalopramFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
61ClindamycinFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
62DoxycyclineFAERS: 2US FAERS
63ExenatideFAERS: 2US FAERS
64Ezetimibe, Simvastatin Drug CombinationFAERS: 2US FAERS
65Imatinib MesylateFAERS: 2OFFSIDES
US FAERS
66LamotrigineFAERS: 2OFFSIDES
US FAERS
67LansoprazoleFAERS: 2US FAERS
68LapatinibFAERS: 2US FAERS
69LoperamideFAERS: 2US FAERS
70MetforminFAERS: 2US FAERS
71MetoprololFAERS: 2US FAERS
72MoxifloxacinFAERS: 2US FAERS
73NebivololFAERS: 2US FAERS
74NorethindroneFAERS: 2OFFSIDES
US FAERS
75PantoprazoleFAERS: 2US FAERS
76ParoxetineFAERS: 2US FAERS
77RivaroxabanFAERS: 2US FAERS
78Salmeterol XinafoateFAERS: 2OFFSIDES
US FAERS
79Sodium BicarbonateFAERS: 2US FAERS
80SotalolFAERS: 2US FAERS
81TicagrelorFAERS: 2US FAERS
82Umeclidinium bromideFAERS: 2US FAERS
83VoriconazoleFAERS: 2US FAERS
84ledipasvir, sofosbuvir drug combinationFAERS: 2US FAERS
85miglustatFAERS: 2US FAERS
86norgestimate, ethinyl estradiol drug combinationFAERS: 2US FAERS
87pimecrolimusFAERS: 2OFFSIDES
US FAERS
88pirfenidoneFAERS: 2US FAERS
89tofacitinibFAERS: 2US FAERS
902-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chlorideFAERS: 1US FAERS
91AfatinibFAERS: 1US FAERS
92Anoro ElliptaFAERS: 1US FAERS
93Aspirin-oxycodone hydrochloride-oxycodone terephthalate combinationFAERS: 1US FAERS
94AxitinibFAERS: 1US FAERS
95BMS-790052FAERS: 1US FAERS
96BMS201038FAERS: 1US FAERS
97CanagliflozinFAERS: 1US FAERS
98CarvedilolFAERS: 1US FAERS
99CetirizineFAERS: 1US FAERS
100ChlorzoxazoneFAERS: 1US FAERS
101CitalopramFAERS: 1US FAERS
102ClindamycinFAERS: 1US FAERS
103DabigatranFAERS: 1US FAERS
104DesogestrelFAERS: 1US FAERS
105DoxycyclineFAERS: 1US FAERS
106DoxycyclineFAERS: 1US FAERS
107DronedaroneFAERS: 1US FAERS
108EnalaprilFAERS: 1US FAERS
109EstradiolFAERS: 1US FAERS
110Estrogens, Conjugated (USP)FAERS: 1OFFSIDES
US FAERS
111EtoposideFAERS: 1US FAERS
112EzetimibeFAERS: 1US FAERS
113FebuxostatFAERS: 1US FAERS
114FluoxetineFAERS: 1US FAERS
115Fluticasone-Salmeterol Drug CombinationFAERS: 1US FAERS
116Glatiramer AcetateFAERS: 1US FAERS
117HydroxychloroquineFAERS: 1US FAERS
118HydroxyureaFAERS: 1OFFSIDES
US FAERS
119Ibandronic AcidFAERS: 1US FAERS
120IbuprofenFAERS: 1OFFSIDES
US FAERS
121Imatinib MesylateFAERS: 1US FAERS
122Insulin GlargineFAERS: 1US FAERS
123LCZ 696FAERS: 1US FAERS
124LactuloseFAERS: 1US FAERS
125LetrozoleFAERS: 1US FAERS
126LevofloxacinFAERS: 1US FAERS
127LoratadineFAERS: 1OFFSIDES
US FAERS
128LorazepamFAERS: 1US FAERS
129LorcetFAERS: 1US FAERS
130LosartanFAERS: 1US FAERS
131MebendazoleFAERS: 1US FAERS
132Medroxyprogesterone AcetateFAERS: 1OFFSIDES
US FAERS
133MefloquineFAERS: 1US FAERS
134MesalamineFAERS: 1US FAERS
135MethotrexateFAERS: 1US FAERS
136MethylphenidateFAERS: 1US FAERS
137Methylprednisolone HemisuccinateFAERS: 1US FAERS
138NaltrexoneFAERS: 1US FAERS
139Nexium 24hrFAERS: 1US FAERS
140OlanzapineFAERS: 1US FAERS
141Ortho EvraFAERS: 1US FAERS
142Potassium CitrateFAERS: 1US FAERS
143PrednisoneFAERS: 1US FAERS
144PropranololFAERS: 1US FAERS
145Quetiapine FumarateFAERS: 1US FAERS
146RitonavirFAERS: 1US FAERS
147Sildenafil CitrateFAERS: 1OFFSIDES
US FAERS
148SimvastatinFAERS: 1US FAERS
149Solifenacin SuccinateFAERS: 1US FAERS
150TemozolomideFAERS: 1US FAERS
151TenofovirFAERS: 1OFFSIDES
US FAERS
152TetracyclineFAERS: 1US FAERS
153ThalidomideFAERS: 1US FAERS
154TramadolFAERS: 1US FAERS
155ValsartanFAERS: 1US FAERS
156VareniclineFAERS: 1US FAERS
157Vilazodone HydrochlorideFAERS: 1US FAERS
158aliskirenFAERS: 1US FAERS
159amitriptyline, chlordiazepoxide drug combinationFAERS: 1US FAERS
160cefditoren pivoxilFAERS: 1US FAERS
161darifenacinFAERS: 1US FAERS
162drospirenone and ethinyl estradiol combinationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
163eltrombopagFAERS: 1US FAERS
164eprosartanFAERS: 1US FAERS
165fesoterodineFAERS: 1US FAERS
166fluticasone furoateFAERS: 1US FAERS
167indacaterolFAERS: 1US FAERS
168lenvatinibFAERS: 1US FAERS
169levocetirizineFAERS: 1US FAERS
170liposomal amphotericin BFAERS: 1US FAERS
171montelukastFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
172oxybutyninFAERS: 1US FAERS
173palbociclibFAERS: 1US FAERS
174pazopanibFAERS: 1US FAERS
175riociguatFAERS: 1US FAERS
176rizatriptanFAERS: 1US FAERS
177rucaparibFAERS: 1US FAERS
178tegaserodFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
179telithromycinFAERS: 1US FAERS
180teriflunomideFAERS: 1US FAERS
181ziprasidoneFAERS: 1US FAERS
182AdapaleneOFFSIDES
183AmlodipineOFFSIDES
184AspirinCanada Vigilance: 1Canada Vigilance
185BosentanOFFSIDES
186BupropionOFFSIDES
187CapecitabineOFFSIDES
188ChlorhexidineOFFSIDES
189CitalopramCanada Vigilance: 1Canada Vigilance
190ClomipramineOFFSIDES
191ClonidineOFFSIDES
192ColchicineSIDER
193DicyclomineOFFSIDES
194DiphenoxylateOFFSIDES
195DroperidolOFFSIDES
196EthosuximideOFFSIDES
197FulvestrantOFFSIDES
198LovastatinOFFSIDES
199MedroxyprogesteroneOFFSIDES
200MefloquineOFFSIDES
201MelatoninOFFSIDES
202MeperidineOFFSIDES
203MethyltestosteroneOFFSIDES
204MinocyclineOFFSIDES
205MinoxidilOFFSIDES
206NabumetoneOFFSIDES
207Norethindrone AcetateOFFSIDES
208PamidronateOFFSIDES
209Penicillin VOFFSIDES
210PenicillinsOFFSIDES
211PerphenazineOFFSIDES
212PiroxicamOFFSIDES
213RabeprazoleCanada Vigilance: 1Canada Vigilance
214RamiprilCanada Vigilance: 1Canada Vigilance
215RibavirinOFFSIDES
216RivastigmineOFFSIDES
217Salmeterol XinafoateOFFSIDES
218SimethiconeOFFSIDES
219SorafenibCanada Vigilance: 1Canada Vigilance
220SulindacOFFSIDES
221TadalafilOFFSIDES
222TamoxifenOFFSIDES
223TelmisartanCanada Vigilance: 1Canada Vigilance
224ToremifeneOFFSIDES
225TretinoinOFFSIDES
226TriazolamOFFSIDES
227Venlafaxine HydrochlorideCanada Vigilance: 1Canada Vigilance
228Vitamin AOFFSIDES
229Vitamin B 12OFFSIDES
230alfuzosinOFFSIDES
231butalbitalOFFSIDES
232chlorhexidine gluconateOFFSIDES
233cyclobenzaprineOFFSIDES
234entecavirSIDER
235exemestaneOFFSIDES
236fenoterol, ipratropium drug combinationOFFSIDES
237reviparinOFFSIDES
238ropiniroleSIDER
239zaleplonSIDER
Similar ADE(s)
NameSemantic Similarity
1Galactosemias39.1%
2Glycogen Storage Disease37.3%
3Leigh Disease36.9%
4Celiac Disease36.4%
5Sprue, Tropical36.4%
6Steatorrhea36.4%
7Sprue36.4%
8Glycogen storage disease type II32.4%
9Hyperhomocysteinemia31.4%
10Brain Diseases, Metabolic, Inborn30.7%
11Smith-Lemli-Opitz Syndrome29.9%
12Amino Acid Metabolism, Inborn Errors29.5%
13Metal Metabolism, Inborn Errors29.5%
14Progeria29.5%
15Lysosomal Storage Diseases29.5%
16Peroxisomal Disorders29.5%
17Mucopolysaccharidosis III28.9%
18Urea Cycle Disorders, Inborn28.8%
19Tyrosinemias28.8%
20Pseudohypoparathyroidism28.7%
21Glycogen Storage Disease Type I28.2%
22Glycogen Storage Disease Type V28.2%
23Carbamoyl-Phosphate Synthase I Deficiency Disease26.3%
24Hyperphosphaturia26.1%
25Mucopolysaccharidosis II24.9%
26Wasting Syndrome24.6%
27Hypolipoproteinemias24.1%
28Homocystinuria23.8%
29Hyperlipoproteinemia Type IV23.3%
30Hyperlipoproteinemia Type V23.3%
31Menkes Kinky Hair Syndrome23.3%
32Gaucher Disease23.3%
33Hypercalcemia23%
34Hypocalcemia23%
35Milk-Alkali Syndrome23%
36Cytochrome-c Oxidase Deficiency23%
37Adrenoleukodystrophy22.8%
38Zellweger Syndrome22.6%
39Hyperlipidemia, Familial Combined22.6%
40Hepatolenticular Degeneration22.5%
41Hyperlipoproteinemia Type III21.9%
42Acid-Base Imbalance21.9%
43Calcium Metabolism Disorders21.9%
44Iron Metabolism Disorders21.9%
45Phosphorus Metabolism Disorders21.9%
46Water-Electrolyte Imbalance21.9%
47Lipid Metabolism Disorders21.9%
48Mitochondrial Diseases21.9%
49Glucose Metabolism Disorders21.9%
50Familial Hypophosphatemic Rickets21.6%
51Refsum Disease20.9%
52Fabry Disease20.8%
53Amyloid Neuropathies, Familial20.6%
54Tay-Sachs Disease20.1%
55Alkaptonuria20%
56Hypophosphatasia20%
57Propionic acidemia20%
58Dihydropyrimidine Dehydrogenase Deficiency20%
59Cystinosis20%
60Werner Syndrome19.9%
61Lipodystrophy19.7%
62Niemann-Pick Disease, Type C19.6%
63Neuronal Ceroid-Lipofuscinoses19%
64Renal tubular acidosis18.7%
65Hypoalphalipoproteinemias18.6%
66Rickets18.6%
67Osteopenia18.4%
68Brain Diseases, Metabolic18.2%
69Zollinger-Ellison syndrome17.4%
70Congenital Hyperinsulinism16.6%
71Albinism16.5%
72Achlorhydria16.4%
73Dysentery16.4%
74Enteritis16.4%
75Enterocolitis16.4%
76Inflammatory Bowel Diseases16.4%
77Short Bowel Syndrome16.3%
78Colorectal Neoplasms16.2%
79MELAS Syndrome15.8%
80Duodenitis15.7%
81Ileitis15.7%
82Erosive Duodenitis15.7%
83Proctocolitis15.6%
84Glycosuria, Renal15.2%
85Familial Periodic Paralysis15.2%
86Duodenal Obstruction15.1%
87Ichthyosis, X-Linked15.1%
88Renal Aminoacidurias14.9%
89Fanconi Syndrome14.9%
90Pseudohypoaldosteronism14.9%
91Liddle Syndrome14.9%
92Porphyrias, Hepatic14.5%
93Sjogren-Larsson Syndrome14.4%
94Antley-Bixler Syndrome Phenotype14.1%
95Cockayne Syndrome13.8%
96Intestinal Atresia13.7%
97Acidosis13.7%
98Alkalosis13.7%
99Amyloidosis13.7%
100Calcinosis13.7%
101Cecal Diseases13.7%
102Colonic Diseases13.7%
103Hyperglycemia13.7%
104Hyperinsulinism13.7%
105Hyperkalemia13.7%
106Hypernatremia13.7%
107Hypoglycemia13.7%
108Hypokalemia13.7%
109Hyponatremia13.7%
110Ileal Diseases13.7%
111Intestinal Obstruction13.7%
112Intestinal Perforation13.7%
113Jejunal Diseases13.7%
114Pneumatosis Cystoides Intestinalis13.7%
115Rectal Diseases13.7%
116Xanthomatosis13.7%
117Hypophosphatemia13.7%
118Metabolic acidosis13.7%
119Dyslipidemias13.7%
120Iron Overload13.7%
121Cronkhite-Canada Syndrome13.7%
122Xanthoma13.7%
123Intestinal Polyposis13.7%
124Gout13.6%
125Intestinal Neoplasms13.5%
126Osteomalacia13.4%
127Canavan Disease13.4%
128Alexander Disease13.4%
129Bloom Syndrome13.1%
130Mitochondrial Encephalomyopathies13%
131Cecal Neoplasms12.9%
132Duodenal Neoplasms12.9%
133Nutrition Disorders12.9%
134Rectal Fistula12.6%
135Anal Fistula12.6%
136Diabetic Ketoacidosis12.5%
137Colitis12.5%
138Duodenogastric Reflux12.5%
139Peptic Ulcer12.5%
140Proctitis12.5%
141Adenomatous Polyposis Coli12.5%
142Mesenteric vascular insufficiency12.4%
143Mesenteric Vascular Occlusion12.3%
144Intestinal Fistula12.3%
145Enterocutaneous Fistula12.3%
146Fanconi Anemia12.2%
147Nesidioblastosis12.2%
148Diabetes Mellitus11.9%
149Intestinal Diseases, Parasitic11.9%
150Pouchitis11.7%
151Dehydration11.6%
152Lipomatosis11.6%
153Water Intoxication11.6%
154Hypokalemic periodic paralysis11.5%
155Osteoporosis11.5%
156Bone Demineralization, Pathologic11.5%
157Post-Traumatic Osteoporosis11.5%
158Cystinuria11.4%
159Reye Syndrome11.2%
160Ataxia Telangiectasia10.9%
161Crohn Disease10.8%
162Enterocolitis, Neutropenic10.8%
163Necrotizing Enterocolitis10.8%
164Appendicitis10.7%
165Hepatic Encephalopathy10.7%
166Cystic Fibrosis10.6%
167Anus Neoplasms10.5%
168Sigmoid Neoplasms10.5%
169Colonic Pseudo-Obstruction10.3%
170Arthritis, Gouty10.3%
171HIV Wasting Syndrome10.2%
172Mitochondrial Myopathies10%
173Esophageal Diseases9.9%
174Gastroenteritis9.9%
175Stomach Diseases9.9%
176Myelinolysis, Central Pontine9.9%
177Esophagitis9.8%
178Gastritis9.8%
179Glycosuria9.8%
180Renal Osteodystrophy9.8%
181Renal rickets9.8%
182Variegate Porphyria9.8%
183Acute intermittent porphyria9.8%
184Porphyria Cutanea Tarda9.8%
185Optic Atrophy, Hereditary, Leber9.7%
186Acidosis, Lactic9.7%
187Calciphylaxis9.7%
188Hemosiderosis9.7%
189Ketosis9.7%
190Ketonuria9.7%
191Ketoacidosis9.7%
192Ketonemia9.7%
193Vascular calcification9.7%
194Friedreich Ataxia9.7%
195HIV-Associated Lipodystrophy Syndrome9.7%
196Appendiceal Neoplasms9.6%
197Colonic Neoplasms9.6%
198Rectal Neoplasms9.6%
199Gastrointestinal Neoplasms9.6%
200Peutz-Jeghers Syndrome9.4%
201Enterocolitis, Pseudomembranous9.3%
202pseudomembranous colitis9.3%
203Dysentery, Bacillary9.3%
204Xeroderma Pigmentosum9.1%
205Colonic Diseases, Functional9.1%
206Fecal Incontinence9.1%
207Fecal Impaction9.1%
208Intussusception9.1%
209Megacolon9.1%
210Ileus9.1%
211Meconium ileus9.1%
212Duodenal Ulcer8.9%
213Peptic Ulcer Perforation8.9%
214Gastric ulcer8.9%
215Wernicke Encephalopathy8.8%
216Stomach Neoplasms8.6%
217Necrobiosis Lipoidica Diabeticorum8.6%
218Neoplastic Syndromes, Hereditary8.6%
219CHARGE Syndrome8.5%
220Aicardi's syndrome8.3%
221Gastrointestinal Hemorrhage8.3%
222Multiple Epiphyseal Dysplasia8.3%
223Osteochondrodysplasias8.3%
224Pelger-Huet Anomaly8.3%
225Myasthenic Syndromes, Congenital8.3%
226Tuberculosis, Gastrointestinal8.2%
227Acidosis, Respiratory8.2%
228Adiposis Dolorosa8.2%
229Alkalosis, Respiratory8.2%
230Insulin Resistance8.1%
231Osteoporosis, Postmenopausal8.1%
232Esophageal Atresia8.1%
233Kernicterus7.9%
234Hypercholesterolemia7.8%
235Hyperlipoproteinemias7.8%
236Hypertriglyceridemia7.8%
237Colitis, Ischemic7.7%
238Hemorrhoids7.7%
239Esophageal Neoplasms7.7%
240Afferent Loop Syndrome7.6%
241Rectocele7.6%
242Kearns-Sayre syndrome7.6%
243Rectal Prolapse7.6%
244Nail-Patella Syndrome7.5%
245Anemia, Sickle Cell7.4%
246Thalassemia7.4%
247Muscular Dystrophy, Duchenne7.3%
248Dwarfism7.3%
249Lactose Intolerance7.3%
250Child Nutrition Disorders7.3%
251Hypervitaminosis A7.3%
252Infant Nutrition Disorders7.3%
253Malnutrition7.3%
254Prader-Willi Syndrome7.3%
255Fragile X Syndrome7.2%
256Gestational Diabetes7.1%
257Latent Autoimmune Diabetes in Adults7.1%
258Diabetes Mellitus, Experimental7.1%
259Muscular Dystrophy7.1%
260Osteogenesis Imperfecta7.1%
261Beckwith-Wiedemann Syndrome7%
262Wolf-Hirschhorn Syndrome7%
263Nephrocalcinosis7%
264Tetany7%
265Cerebral Amyloid Angiopathy6.9%
266Anal Fissure6.8%
267Intestinal Pseudo-Obstruction6.8%
268Irritable Bowel Syndrome6.8%
269Superior Mesenteric Artery Syndrome6.8%
270Neurogenic Bowel6.8%
271Anal Ulcer6.8%
272Giardiasis6.7%
273Carbohydrate Metabolism, Inborn Errors6.6%
274Esophageal and Gastric Varices6.6%
275CREST Syndrome6.3%
276Autoimmune Lymphoproliferative Syndrome6.3%
277Alstrom Syndrome6.3%
278Smith-Magenis syndrome6.2%
279Cri-du-Chat Syndrome6.1%
280Down Syndrome6.1%
281Angioedemas, Hereditary6.1%
282Primary amyloidosis6.1%
283Trisomy 216.1%
284Biliary Tract Diseases6.1%
285Liver diseases6.1%
286Pancreatic Diseases6.1%
287Deformity6.1%
288Marfan Syndrome6.1%
289Kartagener Syndrome6%
290Wiskott-Aldrich Syndrome5.9%
291Esophageal Stenosis5.9%
292Familial Mediterranean Fever5.9%
293Gastric Dilatation5.9%
294Gastric outlet obstruction5.9%
295Pruritus Ani5.7%
296Holoprosencephaly5.7%
297Gastrointestinal Stromal Tumors5.6%
298Rett Syndrome5.5%
299Ectodermal Dysplasia5.5%
300Aplasia Cutis Congenita5.5%
301Amyotrophic Lateral Sclerosis5.5%
302Kallmann Syndrome5.4%
303Myotonic Dystrophy5.3%
304Digestive System Neoplasms5.1%
305Fetal Diseases5.1%
306Esophageal Perforation5.1%
307Rubinstein-Taybi Syndrome5.1%
308Tuberous Sclerosis5%
309Barrett Esophagus5%
310Deglutition Disorders5%
311Gastric Antral Vascular Ectasia4.9%
312Peptic Ulcer Hemorrhage4.9%
313Gastroparesis4.9%
314Polycystic Kidney Diseases4.9%
315Williams Syndrome4.9%
316Sickle Cell Trait4.8%
317Frontotemporal dementia4.8%
318Liver neoplasms4.8%
319Pancreatic Fistula4.8%
320Primary Ciliary Dyskinesia4.7%
321Cryptosporidiosis4.6%
322Choledochal Cyst4.6%
323Deficiency Diseases4.6%
324Starvation4.6%
325Refeeding Syndrome4.6%
326Retinal Dysplasia4.5%
327Aniridia4.5%
328Anus, Imperforate4.4%
329Anorectal Malformations4.4%
330Epidermolysis Bullosa4.4%
331Cutis Laxa4.3%
332Melena4.2%
333Retinitis Pigmentosa4.2%
334Pigmentary retinopathy4.2%
335Porokeratosis4.2%
336Keratoderma, Palmoplantar4.2%
337Chronic granulomatous disease4.2%
338Hematemesis4.2%
339Peritoneal Neoplasms4.2%
340Welander Distal Myopathy4.2%
341Acute Chest Syndrome4%
342Esophageal motility disorders3.9%
343Mallory-Weiss Syndrome3.9%
344Pyloric Stenosis3.9%
345Duane Retraction Syndrome3.8%
346Meconium Aspiration Syndrome3.7%
347Pancreatic Neoplasm3.7%
348Bile Duct Neoplasms3.7%
349gallbladder neoplasm3.7%
350Myotonia Congenita3.7%
351Thrombasthenia3.7%
352Antithrombin III Deficiency3.7%
353Protein C Deficiency3.7%
354Afibrinogenemia3.7%
355Dystonia Musculorum Deformans3.7%
356Factor VII Deficiency3.7%
357Factor X Deficiency3.7%
358Factor XII Deficiency3.7%
359Hemophilia A3.7%
360Activated Protein C Resistance3.7%
361Factor II deficiency3.7%
362Factor VIII Deficiency3.7%
363Factor V deficiency3.7%
364Factor XI Deficiency3.7%
365Hypoprothrombinemias3.7%
366Lafora Disease3.6%
367Unverricht-Lundborg Syndrome3.6%
368Anemia, Diamond-Blackfan3.6%
369Pseudoxanthoma Elasticum3.6%
370Biliary cirrhosis3.5%
371Multiple Endocrine Neoplasia3.4%
372Xeroderma3.3%
373Mobius Syndrome3.3%
374Abdominal Cramps3.3%
375Abnormalities, Drug-Induced3.3%
376Amniotic Band Syndrome3.3%
377Asphyxia Neonatorum3.3%
378Bile Duct Diseases3.3%
379Cholelithiasis3.3%
380Chylous Ascites3.3%
381Fatty Liver3.3%
382Hepatitis3.3%
383Portal Hypertension3.3%
384Infant, Premature, Diseases3.3%
385Liver Cirrhosis3.3%
386Pancreatic Insufficiency3.3%
387Pancreatitis3.3%
388Pneumoperitoneum3.3%
389Situs Inversus3.3%
390Infantile Colic3.3%
391Focal Nodular Hyperplasia3.3%
392Hepatic Insufficiency3.3%
393Steatohepatitis3.3%
394Congenital Hypothyroidism3.3%
395Dermatitis, Atopic3.3%
396Cholecystolithiasis3.3%
397Kwashiorkor3.2%
398Magnesium Deficiency3.2%
399Potassium Deficiency3.2%
400Protein Deficiency3.2%
401Avitaminosis3.2%
402Diverticulitis3.2%
403Dumping Syndrome3.2%
404Polycystic Kidney, Autosomal Dominant3.2%
405Classical Lissencephalies and Subcortical Band Heterotopias3.1%
406Hyperkeratosis, Epidermolytic3.1%
407Basal Cell Nevus Syndrome3%
408Behcet Syndrome3%
409Esophageal Achalasia2.9%
410Charcot-Marie-Tooth Disease2.9%
411Eye Abnormalities2.9%
412Liver Diseases, Parasitic2.9%
413Cardiovascular Abnormalities2.9%
414Obesity2.8%
415Diverticulum2.8%
416Diverticulosis2.8%
417Fatty Liver, Alcoholic2.8%
418Hepatitis, Alcoholic2.8%
419Liver Cirrhosis, Alcoholic2.8%
420Hepatic Veno-Occlusive Disease2.8%
421Pancreatic Cyst2.8%
422Peliosis Hepatis2.8%
423Skin Abnormalities2.8%
424Lymphatic Abnormalities2.8%
425Hepatopulmonary Syndrome2.8%
426Congenital Microtia2.8%
427Papillon-Lefevre Disease2.8%
428Anemia, Neonatal2.8%
429Hemoperitoneum2.8%
430Hepatomegaly2.8%
431Mesenteric Panniculitis2.8%
432Panniculitis, Peritoneal2.8%
433Peritonitis2.8%
434Persistent Fetal Circulation Syndrome2.8%
435Peritoneal Fibrosis2.8%
436Encapsulating Peritoneal Sclerosis2.8%
437Biliary Fistula2.7%
438Gastric Fistula2.7%
439Congenital diaphragmatic hernia2.7%
440Hepatic Vein Thrombosis2.7%
441Umbilical hernia2.7%
442Liver Abscess2.7%
443Budd-Chiari Syndrome2.7%
444Choledocholithiasis2.7%
445Huntington Disease2.7%
446Ascorbic Acid Deficiency2.6%
447Vitamin A Deficiency2.6%
448Vitamin D Deficiency2.6%
449Vitamin E Deficiency2.6%
450Marasmus2.6%
451Urogenital Abnormalities2.5%
452Nephroblastoma2.4%
453Hepatocellular Adenoma2.4%
454Neonatal Abstinence Syndrome2.4%
455Chemical and Drug Induced Liver Injury2.4%
456Fetal Growth Retardation2.4%
457Hepatorenal Syndrome2.4%
458Fetal Hypoxia2.4%
459Congenital nystagmus2.4%
460Fetal Alcohol Spectrum Disorders2.4%
461Toxoplasmosis, Congenital2.3%
462Anencephaly2.3%
463Syphilis, Congenital2.3%
464Obesity, Abdominal2.3%
465Folic Acid Deficiency2.3%
466Pellagra2.3%
467Thiamine Deficiency2.3%
468Vitamin B 12 Deficiency2.3%
469Vitamin B 6 Deficiency2.3%
470Pyridoxine Deficiency2.3%
471Hydrops Fetalis2.2%
472Liver Abscess, Amebic2.2%
473Klinefelter Syndrome2.2%
474Liver Neoplasms, Experimental2.2%
475Multiple Endocrine Neoplasia Type 12.2%
476Beriberi2.1%
477Turner Syndrome2.1%
478Chorioamnionitis2.1%
479Maxillofacial Abnormalities2.1%
480Dural Arteriovenous Fistula2.1%
481Laryngopharyngeal Reflux2.1%
482Dextrocardia2%
483Pediatric Obesity2%
484Cholangitis2%
485Cholecystitis2%
486Cholestasis2%
487Common Bile Duct Diseases2%
488Hepatitis, Chronic2%
489Prune Belly Syndrome2%
490Twins, Conjoined2%
491Liver Failure2%
492Pancreatitis, Chronic2%
493Non-alcoholic Fatty Liver Disease2%
494Chronic active hepatitis2%
495Waardenburg Syndrome2%
496Vitamin K Deficiency1.9%
497Abnormalities, Radiation-Induced1.8%
498Carcinoma, Pancreatic Ductal1.8%
499Anemia, Pernicious1.7%
500Hepatitis, Animal1.7%
501Hepatitis, Viral, Human1.7%
502Scimitar Syndrome1.7%
503Anophthalmos1.7%
504Hydranencephaly1.7%
505Microphthalmos1.7%
506Neural Tube Defects1.7%
507Paralysis, Obstetric1.7%
508Retinopathy of Prematurity1.7%
509Tethered Cord Syndrome1.7%
510Iniencephaly1.7%
511Craniorachischisis1.7%
512Limb Deformities, Congenital1.7%
513Exencephaly1.7%
514Septo-Optic Dysplasia1.7%
515Craniofacial Abnormalities1.7%
516Cortical Dysplasia1.7%
517Malformations of Cortical Development1.7%
518Liver Cirrhosis, Experimental1.6%
519Pancreatic Pseudocyst1.6%
520Bronchopulmonary Dysplasia1.6%
521Pancreatitis, Alcoholic1.6%
522Ophthalmia Neonatorum1.6%
523Scurvy1.6%
524Denys-Drash Syndrome1.5%
525Craniosynostosis1.4%
526Syndactyly1.4%
527Brachycephaly1.4%
528Blepharophimosis1.4%
529Laryngostenosis1.4%
530Mouth Abnormalities1.4%
531Respiratory Distress Syndrome, Newborn1.4%
532Fascioliasis1.4%
533Horseshoe Kidney1.4%
534Pectus excavatum1.4%
535Microcephaly1.4%
536Macrocephaly1.4%
537Hepatitis B, Chronic1.4%
538Hepatitis C, Chronic1.4%
539Echinococcosis, Hepatic1.4%
540Klippel-Feil Syndrome1.4%
541Gastroschisis1.4%
542Synostosis1.4%
543Acrodermatitis1.4%
544Lymphangiectasis, Intestinal1.4%
545Gianotti-Crosti Syndrome1.4%
546Chemical and Drug Induced Liver Injury, Chronic1.4%
547Acrocephalosyndactylia1.4%
548Noonan Syndrome1.3%
549Cholestasis, Extrahepatic1.3%
550Biliary Dyskinesia1.3%
551Cholangitis, Sclerosing1.3%
552Liver Failure, Acute1.3%
553Acalculous Cholecystitis1.3%
554End Stage Liver Disease1.3%
555insulinoma1.3%
556Gastrinoma1.3%
557Glucagonoma1.3%
558Arthrogryposis1.3%
559Choanal Atresia1.3%
560Tracheobronchomegaly1.3%
561Laryngocele1.3%
562Hermaphroditism1.3%
563Disorders of Sex Development1.3%
564Cryptorchidism1.2%
565Hypospadias1.2%
566Central Nervous System Cysts1.2%
567Dandy-Walker Syndrome1.2%
568Leukomalacia, Periventricular1.2%
569POEMS Syndrome1.2%
570Porencephaly1.2%
571Subacute Combined Degeneration1.2%
572Cleft Palate1.2%
573Vipoma1.2%
574Jaw Abnormalities1.2%
575Laryngomalacia1.1%
576Pectus carinatum1.1%
577Bladder Exstrophy1.1%
578Epispadias1.1%
579Autoimmune hepatitis1.1%
580Multicystic Dysplastic Kidney1.1%
581Amelia1.1%
582Arachnodactyly1.1%
583Ectopia Cordis1.1%
584Ectromelia1.1%
585Hemimelia1.1%
586Meningomyelocele1.1%
587Phocomelia1.1%
588Sirenomelia1.1%
589Spina Bifida1.1%
590Polydactyly1.1%
591Brachydactyly1.1%
592Plagiocephaly1.1%
593Lower Extremity Deformities, Congenital1.1%
594Upper Extremity Deformities, Congenital1.1%
595Single umbilical artery1.1%
596Poland Syndrome1.1%
597Massive Hepatic Necrosis1%
598Hepatitis, Viral, Animal1%
599Emphysematous Cholecystitis1%
600Sphincter of Oddi Dysfunction1%
601Hepatitis E1%
602Hepatitis B0.9%
603Hepatitis C0.9%
604Hepatitis A0.9%
605Aortic coarctation0.9%
606Cor Triatriatum0.9%
607Coronary Vessel Anomalies0.9%
608Dental Enamel Hypoplasia0.9%
609Patent ductus arteriosus0.9%
610Ebstein Anomaly0.9%
611Heart Septal Defects0.9%
612Hyaline Membrane Disease0.9%
613Hypodontia0.9%
614Macrostomia0.9%
615Meningocele0.9%
616Microstomia0.9%
617Tetralogy of Fallot0.9%
618Transposition of Great Vessels0.9%
619Hypoplastic Left Heart Syndrome0.9%
620May-Thurner Syndrome0.9%
621Encephalocele0.9%
622Craniofacial Dysostosis0.9%
623Wolff-Parkinson-White Syndrome0.9%
624Micrognathism0.9%
625Pierre Robin Syndrome0.9%
626Long QT Syndrome0.8%
627Platybasia0.8%
628Tricuspid Atresia0.8%
629Arrhythmogenic Right Ventricular Dysplasia0.8%
630Gonadal Dysgenesis0.8%
631Bronchomalacia0.8%
632Adrenogenital Syndrome0.8%
633Tracheomalacia0.8%
634Ovotesticular Disorders of Sex Development0.8%
635Retrognathia0.8%
636Dermal Sinus0.8%
637Spina Bifida Cystica0.8%
638Spina Bifida Occulta0.8%
639Lissencephaly0.8%
640Polymicrogyria0.8%
641Pachygyria0.8%
642Schizencephaly0.8%
643Periventricular Nodular Heterotopia0.8%
644Hyperandrogenism0.8%
645Prognathism0.7%
646Aortopulmonary Septal Defect0.7%
647Double Outlet Right Ventricle0.7%
648Endocardial Cushion Defects0.7%
649Myocardial bridging0.7%
650Aorticopulmonary Septal Defect0.7%
651Mandibulofacial Dysostosis0.6%
652Romano-Ward Syndrome0.6%
653Truncus Arteriosus, Persistent0.6%
654Goldenhar Syndrome0.6%
655Talipes0.5%
656Rift Valley Fever0.5%
657Arteriovenous fistula0.5%
658Congenital clubfoot0.5%
659Vertical Talus0.5%
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