MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Laryngomalacia

(UMLS:C0264303)

Definition:: A congenital or acquired condition of underdeveloped or degeneration of CARTILAGE in the LARYNX. This results in a floppy laryngeal wall making patency difficult to maintain.
UMLS ID:: C0264303
MeSH ID:: D055092

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.182.310

Classification 2:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.360.563

Classification 3:

Name:

Otorhinolaryngologic Diseases
MeSH Tree Number(s):: C09.400.563

Classification 4:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.621.568

Classification 5:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.300.182.310

Synonym(s)

Laryngomalacia

LARYNGOMALACIA

Softening of voice box tissue

laryngomalacia

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Paroxetine	FAERS: 10		US FAERS
2	Levetiracetam	FAERS: 5		US FAERS
3	Ondansetron	FAERS: 5		US FAERS
4	Sertraline	FAERS: 5		US FAERS
5	17 alpha-Hydroxyprogesterone Caproate	FAERS: 3		US FAERS
6	Fluoxetine	FAERS: 3		US FAERS
7	Prednisolone	FAERS: 3		US FAERS
8	tazarotene	FAERS: 3		OFFSIDES US FAERS
9	Lamotrigine	FAERS: 2		US FAERS
10	Letrozole	FAERS: 2		OFFSIDES US FAERS
11	Valproic Acid	FAERS: 2		US FAERS
12	Valproic Acid	FAERS: 2		US FAERS
13	Vigabatrin	FAERS: 2		OFFSIDES US FAERS
14	4-hydroxybutyric acid	FAERS: 1		US FAERS
15	Bupropion	FAERS: 1		OFFSIDES US FAERS
16	Carbamazepine	FAERS: 1		US FAERS
17	Diazoxide	FAERS: 1	17937066	CTD US FAERS
18	Fluticasone-Salmeterol Drug Combination	FAERS: 1		US FAERS
19	Hydromorphone	FAERS: 1		US FAERS
20	Metoclopramide	FAERS: 1		US FAERS
21	Minocycline	FAERS: 1		US FAERS
22	Mycophenolic Acid	FAERS: 1		US FAERS
23	Nevirapine	FAERS: 1		OFFSIDES US FAERS
24	Thyroxine	FAERS: 1		US FAERS
25	Thyroxine	FAERS: 1		US FAERS
26	Venlafaxine Hydrochloride	FAERS: 1		US FAERS
27	dolutegravir	FAERS: 1		US FAERS
28	Bosentan			OFFSIDES
29	Clomipramine			OFFSIDES
30	Clorazepate Dipotassium			OFFSIDES
31	Dicyclomine			OFFSIDES
32	Fluconazole	Canada Vigilance: 3		Canada Vigilance
33	Imiquimod			OFFSIDES
34	Lactulose			OFFSIDES
35	Loperamide			OFFSIDES
36	Mannitol			OFFSIDES
37	Metoclopramide			OFFSIDES
38	Tadenan			OFFSIDES
39	Tenofovir			OFFSIDES
40	Tenofovir			OFFSIDES
41	Zidovudine			OFFSIDES
42	tetrazepam			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Pectus carinatum	32.4%
2	Laryngocele	26.4%
3	Laryngostenosis	26.1%
4	Osteochondritis	26.1%
5	Tietze's Syndrome	25.7%
6	Bronchomalacia	24.8%
7	Tracheomalacia	24.8%
8	Laryngitis	24.6%
9	Vocal Cord Dysfunction	24.6%
10	Laryngeal Edema	24%
11	Laryngeal neoplasm	22.3%
12	Acrocephalosyndactylia	21.5%
13	Granuloma, Laryngeal	21.5%
14	Arthrogryposis	20.2%
15	Craniosynostosis	19.7%
16	Syndactyly	19.7%
17	Brachycephaly	19.7%
18	Voice Disorders	18.6%
19	Voice Disturbance	18.6%
20	Pectus excavatum	18.1%
21	Holoprosencephaly	18%
22	Laryngospasm	17.9%
23	Limb Deformities, Congenital	17.8%
24	Craniofacial Abnormalities	17.8%
25	Croup	17.6%
26	Klippel-Feil Syndrome	17.6%
27	Synostosis	17.6%
28	Rubinstein-Taybi Syndrome	16.8%
29	Noonan Syndrome	16.7%
30	Vocal Cord Paralysis	16.5%
31	Poland Syndrome	16.4%
32	Gastroschisis	15.5%
33	Rheumatism	15.3%
34	Kartagener Syndrome	14.9%
35	Maxillofacial Abnormalities	14.8%
36	Platybasia	14.7%
37	Primary Ciliary Dyskinesia	14.6%
38	Marfan Syndrome	14.5%
39	Choanal Atresia	14%
40	Tracheobronchomegaly	14%
41	Hoarseness	13.6%
42	Aphonia	13.6%
43	Dysphonia	13.6%
44	Craniofacial Dysostosis	13.6%
45	Amelia	13.2%
46	Arachnodactyly	13.2%
47	Ectromelia	13.2%
48	Hemimelia	13.2%
49	Phocomelia	13.2%
50	Sirenomelia	13.2%
51	Polydactyly	13.2%
52	Brachydactyly	13.2%
53	Plagiocephaly	13.2%
54	Lower Extremity Deformities, Congenital	13.2%
55	Upper Extremity Deformities, Congenital	13.2%
56	Congenital Microtia	13%
57	Microcephaly	12.9%
58	Macrocephaly	12.9%
59	Nose Diseases	12.5%
60	Ectodermal Dysplasia	12.2%
61	Aplasia Cutis Congenita	12.2%
62	Jaw Abnormalities	12.2%
63	Polymyalgia Rheumatica	12.2%
64	Talipes	12.1%
65	Lupus Erythematosus, Cutaneous	12%
66	Panniculitis	12%
67	Systemic Scleroderma	12%
68	Skin Abnormalities	12%
69	Morphea	12%
70	Beckwith-Wiedemann Syndrome	12%
71	Wolf-Hirschhorn Syndrome	12%
72	Pseudoxanthoma Elasticum	11.9%
73	Laryngopharyngeal Reflux	11.8%
74	Scimitar Syndrome	11.6%
75	Antley-Bixler Syndrome Phenotype	11.6%
76	Nail-Patella Syndrome	11.5%
77	Cutis Laxa	11.2%
78	Porencephaly	11.2%
79	Dermatomyositis	11%
80	Aicardi's syndrome	10.9%
81	Congenital clubfoot	10.8%
82	Vertical Talus	10.8%
83	Smith-Magenis syndrome	10.7%
84	Nose Neoplasms	10.6%
85	Cri-du-Chat Syndrome	10.6%
86	Down Syndrome	10.6%
87	Trisomy 21	10.6%
88	Panniculitis, Lupus Erythematosus	10.5%
89	Rhinitis	10.5%
90	Abnormalities, Drug-Induced	10.5%
91	Collagen Diseases	10.5%
92	Mixed Connective Tissue Disease	10.5%
93	Situs Inversus	10.5%
94	Mucinoses	10.5%
95	Dupuytren Contracture	10.3%
96	Goldenhar Syndrome	10.3%
97	Micrognathism	10.2%
98	Pierre Robin Syndrome	10.2%
99	Prognathism	10.2%
100	Cleft Palate	10.2%
101	Paranasal Sinus Neoplasms	10.1%
102	Mandibulofacial Dysostosis	10.1%
103	Rheumatoid Arthritis	10%
104	Juvenile arthritis	10%
105	Xeroderma	9.9%
106	Osteogenesis Imperfecta	9.9%
107	Bronchitis	9.6%
108	Epidermolysis Bullosa	9.5%
109	Prader-Willi Syndrome	9.5%
110	Retrognathia	9.4%
111	Eye Abnormalities	9.2%
112	Foot Diseases	9.2%
113	Cardiovascular Abnormalities	9.2%
114	Pleuropneumonia	9.1%
115	Meconium Aspiration Syndrome	9%
116	Lupus Erythematosus, Systemic	9%
117	Lymphatic Abnormalities	9%
118	Overlap syndrome	9%
119	Anencephaly	8.9%
120	Congenital diaphragmatic hernia	8.9%
121	Respiratory Distress Syndrome, Newborn	8.7%
122	Bronchopneumonia	8.6%
123	Sinusitis	8.6%
124	Acrodermatitis	8.5%
125	Gianotti-Crosti Syndrome	8.5%
126	Rheumatoid Nodule	8.5%
127	Asthma	8.4%
128	Xeroderma Pigmentosum	8.4%
129	Maxillary Sinus Neoplasms	8.3%
130	Bronchitis, Chronic	8.3%
131	Ichthyosis, X-Linked	8.1%
132	Urogenital Abnormalities	8%
133	Contracture	8%
134	Granuloma, Lethal Midline	8%
135	Nose Deformities, Acquired	8%
136	Osteoarthropathy, Secondary Hypertrophic	8%
137	Pleurisy	8%
138	Pneumonia	8%
139	Lobar Pneumonia	8%
140	Respiratory Distress Syndrome, Adult	8%
141	Tracheitis	8%
142	Fasciitis, Plantar	8%
143	Pneumonitis	8%
144	Dural Arteriovenous Fistula	8%
145	Dextrocardia	7.9%
146	Lupus Erythematosus, Discoid	7.8%
147	Scleroderma, Limited	7.8%
148	Gout	7.8%
149	Cystic Fibrosis	7.8%
150	CHARGE Syndrome	7.8%
151	Cockayne Syndrome	7.7%
152	Rhinoscleroma	7.7%
153	Osteoarthritis, Spine	7.7%
154	Felty Syndrome	7.5%
155	Bronchiolitis	7.2%
156	Bone Diseases	7.1%
157	Bronchial Diseases	7.1%
158	Ear Diseases	7.1%
159	Fasciitis	7.1%
160	Foot Deformities	7.1%
161	Arthropathy	7.1%
162	Lung diseases	7.1%
163	Pleural Diseases	7.1%
164	Respiration Disorders	7.1%
165	Thoracic Diseases	7.1%
166	Tracheal Diseases	7.1%
167	Lung Diseases, Fungal	7%
168	Pharyngitis	7%
169	Sjogren-Larsson Syndrome	7%
170	Fibromyalgia	7%
171	Nasal Polyps	7%
172	Bronchial Fistula	6.9%
173	Ear Neoplasms	6.9%
174	Lung Abscess	6.9%
175	Lung Neoplasms	6.9%
176	Metatarsalgia	6.9%
177	Pleural Neoplasms	6.9%
178	Tuberculosis, Pulmonary	6.9%
179	Prune Belly Syndrome	6.9%
180	Twins, Conjoined	6.9%
181	Scleromyxedema	6.9%
182	Waardenburg Syndrome	6.9%
183	Mobius Syndrome	6.9%
184	Cellulitis	6.8%
185	Ischemic contracture	6.8%
186	Pleural Effusion, Malignant	6.8%
187	Acute Chest Syndrome	6.8%
188	Rheumatoid Vasculitis	6.7%
189	Alstrom Syndrome	6.7%
190	Arthritis, Psoriatic	6.6%
191	Temporomandibular Joint Disorders	6.6%
192	Temporomandibular Joint Dysfunction Syndrome	6.6%
193	Homocystinuria	6.5%
194	Hyperkeratosis, Epidermolytic	6.5%
195	Basal Cell Nevus Syndrome	6.5%
196	Aspergillosis, Allergic Bronchopulmonary	6.4%
197	Necrobiosis Lipoidica Diabeticorum	6.4%
198	Hyaline Membrane Disease	6.4%
199	Erythema Induratum	6.3%
200	Jaw Diseases	6.2%
201	Pharyngeal Diseases	6.2%
202	Ankylosing spondylitis	6.2%
203	Turner Syndrome	6.2%
204	Arthritis, Gouty	6.2%
205	Pharyngeal Neoplasms	6.2%
206	Epistaxis	6.2%
207	Tracheal Neoplasms	6.1%
208	Myopathy	6.1%
209	Nasopharyngitis	6.1%
210	Respiratory Tract Infections	6.1%
211	Abnormalities, Radiation-Induced	6.1%
212	Sicca Syndrome	6.1%
213	Sjogren's Syndrome	6.1%
214	Granuloma, Respiratory Tract	6.1%
215	Respiratory Hypersensitivity	6.1%
216	Respiratory Tract Fistula	6.1%
217	Fragile X Syndrome	6%
218	Rheumatic Fever	6%
219	Polycystic Kidney Diseases	6%
220	Williams Syndrome	6%
221	Bronchial Neoplasms	6%
222	Hay fever	6%
223	Rhinitis, Allergic, Perennial	6%
224	Genetic Diseases, Inborn	6%
225	Anophthalmos	5.9%
226	Anus, Imperforate	5.9%
227	Hydranencephaly	5.9%
228	Mesenteric Panniculitis	5.9%
229	Microphthalmos	5.9%
230	Multiple Epiphyseal Dysplasia	5.9%
231	Neural Tube Defects	5.9%
232	Osteochondrodysplasias	5.9%
233	Panniculitis, Peritoneal	5.9%
234	Persistent Fetal Circulation Syndrome	5.9%
235	Tethered Cord Syndrome	5.9%
236	Orbital Cellulitis	5.9%
237	Iniencephaly	5.9%
238	Craniorachischisis	5.9%
239	Exencephaly	5.9%
240	Septo-Optic Dysplasia	5.9%
241	Cortical Dysplasia	5.9%
242	Myxoid cyst	5.9%
243	Malformations of Cortical Development	5.9%
244	Anorectal Malformations	5.9%
245	Bloom Syndrome	5.9%
246	Hip Contracture	5.9%
247	Labyrinthitis	5.9%
248	Myxedema	5.9%
249	Periarthritis	5.9%
250	Aspiration Pneumonia	5.9%
251	Rhinitis, Vasomotor	5.9%
252	Classical Lissencephalies and Subcortical Band Heterotopias	5.7%
253	Retinal Dysplasia	5.6%
254	Granuloma Annulare	5.5%
255	Nasopharyngeal Neoplasms	5.5%
256	Aniridia	5.5%
257	Smith-Lemli-Opitz Syndrome	5.5%
258	Dermatitis, Atopic	5.4%
259	Osteoarthritis, Knee	5.4%
260	Idiopathic Pulmonary Fibrosis	5.4%
261	Myotonic Dystrophy	5.3%
262	Dwarfism	5.3%
263	Pneumoconiosis	5.3%
264	Pneumonia, Viral	5.3%
265	Blepharophimosis	5.2%
266	Mouth Abnormalities	5.2%
267	Pneumonia, Bacterial	5.2%
268	Esophageal Atresia	5.2%
269	Intestinal Atresia	5.2%
270	Horseshoe Kidney	5.2%
271	Muscular Dystrophy	5.2%
272	Gigantism	5.1%
273	Lymphangiectasis, Intestinal	5.1%
274	Spinal Neoplasms	5.1%
275	Spondylitis	5.1%
276	Tonsillitis	5.1%
277	Pyoderma Gangrenosum	5.1%
278	Porokeratosis	5.1%
279	Keratoderma, Palmoplantar	5.1%
280	Arthritis, Reactive	5.1%
281	Congenital Hypothyroidism	5.1%
282	Fetal Diseases	5.1%
283	Asthma, Exercise-Induced	5.1%
284	Status Asthmaticus	5.1%
285	Multiple Pulmonary Nodules	5.1%
286	Keloid	5.1%
287	Albinism	5.1%
288	Mucopolysaccharidosis II	5.1%
289	Muscular Dystrophy, Duchenne	4.9%
290	Pneumonia, Lipid	4.9%
291	Klinefelter Syndrome	4.8%
292	Altitude Sickness	4.7%
293	Arthritis	4.7%
294	Atelectasis	4.7%
295	Bone Diseases, Developmental	4.7%
296	Bronchospasm	4.7%
297	Bronchiectasis	4.7%
298	Bursitis	4.7%
299	Chylothorax	4.7%
300	Hydropneumothorax	4.7%
301	Hydrothorax	4.7%
302	Hyperostosis	4.7%
303	Pulmonary Hypertension	4.7%
304	Joint Instability	4.7%
305	Mucopolysaccharidosis III	4.7%
306	Myofascial Pain Syndromes	4.7%
307	Osteitis	4.7%
308	Osteitis Deformans	4.7%
309	Osteochondrosis	4.7%
310	Otosclerosis	4.7%
311	Pneumothorax	4.7%
312	Pulmonary Alveolar Proteinosis	4.7%
313	Pulmonary Edema	4.7%
314	Pulmonary Fibrosis	4.7%
315	Respiratory Insufficiency	4.7%
316	Rhabdomyolysis	4.7%
317	Spinal Diseases	4.7%
318	Synovitis	4.7%
319	Tracheal Stenosis	4.7%
320	Bronchial Hyperreactivity	4.7%
321	Hamman-Rich syndrome	4.7%
322	Joint laxity	4.7%
323	Polyarthritis	4.7%
324	Lung Diseases, Interstitial	4.7%
325	Respiratory Depression	4.7%
326	Frozen shoulder	4.7%
327	Tympanosclerosis	4.7%
328	Lung Diseases, Obstructive	4.7%
329	Patellofemoral Pain Syndrome	4.7%
330	Respiratory Failure	4.7%
331	Asthma, Occupational	4.6%
332	Choledochal Cyst	4.6%
333	Hermaphroditism	4.6%
334	Disorders of Sex Development	4.6%
335	Blastomycosis	4.6%
336	Bronchiolitis Obliterans	4.6%
337	Spondylarthropathies	4.6%
338	Cryptorchidism	4.6%
339	Hypospadias	4.6%
340	Radiation Pneumonitis	4.6%
341	Central Nervous System Cysts	4.6%
342	Radiation Fibrosis	4.6%
343	Dandy-Walker Syndrome	4.5%
344	Retropharyngeal Abscess	4.5%
345	Hypopharyngeal Neoplasms	4.5%
346	Hypopharyngeal Cancer	4.5%
347	POEMS Syndrome	4.5%
348	Lupus Nephritis	4.5%
349	Polycystic Kidney, Autosomal Dominant	4.5%
350	Eosinophilic Granuloma	4.4%
351	Bronchopulmonary Dysplasia	4.4%
352	Ectopia Cordis	4.4%
353	Meningomyelocele	4.4%
354	Spina Bifida	4.4%
355	Single umbilical artery	4.4%
356	Asbestosis	4.3%
357	Berylliosis	4.3%
358	Silicosis	4.3%
359	Discitis	4.2%
360	Mastoiditis	4.2%
361	Petrositis	4.2%
362	Familial Periodic Paralysis	4.2%
363	Farmer's Lung	4.2%
364	Nasopharyngeal carcinoma	4.1%
365	Kallmann Syndrome	4.1%
366	Bladder Exstrophy	4.1%
367	Epispadias	4.1%
368	Bone Diseases, Endocrine	4.1%
369	Tympanic Membrane Perforation	4.1%
370	Asthma, Aspirin-Induced	4.1%
371	Multicystic Dysplastic Kidney	4.1%
372	Charcot-Marie-Tooth Disease	4%
373	Zellweger Syndrome	4%
374	Bone Diseases, Infectious	4%
375	Bone neoplasms	4%
376	Compartment syndromes	4%
377	Maxillary Diseases	4%
378	Osteopenia	4%
379	Otomycosis	4%
380	Tendinitis	4%
381	Lung Injury	4%
382	Hepatopulmonary Syndrome	4%
383	Tendinopathy	4%
384	Respiratory Aspiration	4%
385	Apnea	4%
386	Bone Resorption	4%
387	Cheyne-Stokes Respiration	4%
388	Common Cold	4%
389	Deglutition Disorders	4%
390	Dyspnea	4%
391	Hemarthrosis	4%
392	Hemothorax	4%
393	Hyperventilation	4%
394	Influenza	4%
395	Mouth Breathing	4%
396	Myositis	4%
397	Tachypnea	4%
398	Isaacs syndrome	4%
399	Aseptic Necrosis of Bone	4%
400	Myotonic Disorders	4%
401	Catarrh	4%
402	Pulmonary Embolism	3.9%
403	Pulmonary Eosinophilia	3.9%
404	Severe Acute Respiratory Syndrome	3.9%
405	Eosinophilic Pneumonia	3.9%
406	Acne Vulgaris	3.9%
407	Contact Dermatitis	3.9%
408	Eczema	3.9%
409	Erythema Multiforme	3.9%
410	Intertrigo	3.9%
411	Neurodermatitis	3.9%
412	Rhinophyma	3.9%
413	Perioral Dermatitis	3.9%
414	Acne	3.9%
415	Aortic coarctation	3.8%
416	Cor Triatriatum	3.8%
417	Coronary Vessel Anomalies	3.8%
418	Dental Enamel Hypoplasia	3.8%
419	Patent ductus arteriosus	3.8%
420	Ebstein Anomaly	3.8%
421	Heart Septal Defects	3.8%
422	Hypodontia	3.8%
423	Macrostomia	3.8%
424	Meningocele	3.8%
425	Microstomia	3.8%
426	Tetralogy of Fallot	3.8%
427	Transposition of Great Vessels	3.8%
428	Hypoplastic Left Heart Syndrome	3.8%
429	May-Thurner Syndrome	3.8%
430	Encephalocele	3.8%
431	Hyperandrogenism	3.8%
432	Welander Distal Myopathy	3.8%
433	Papillon-Lefevre Disease	3.8%
434	Wolff-Parkinson-White Syndrome	3.8%
435	Dermatitis, Phototoxic	3.8%
436	Pityriasis Lichenoides et Varioliformis Acuta	3.8%
437	Pityriasis Lichenoides	3.8%
438	Phototoxicity	3.8%
439	Tuberous Sclerosis	3.8%
440	Myotonia Congenita	3.8%
441	Peritonsillar Abscess	3.7%
442	Tonsillar Neoplasms	3.7%
443	Tuberculosis, Spinal	3.7%
444	Refsum Disease	3.7%
445	CREST Syndrome	3.6%
446	Dermal Sinus	3.6%
447	Spina Bifida Cystica	3.6%
448	Spina Bifida Occulta	3.6%
449	Lissencephaly	3.6%
450	Polymicrogyria	3.6%
451	Pachygyria	3.6%
452	Schizencephaly	3.6%
453	Periventricular Nodular Heterotopia	3.6%
454	Menkes Kinky Hair Syndrome	3.5%
455	Abdominal Cramps	3.5%
456	Amniotic Band Syndrome	3.5%
457	Asphyxia Neonatorum	3.5%
458	Breast Diseases	3.5%
459	Dermatitis	3.5%
460	Exanthema	3.5%
461	Facial Dermatoses	3.5%
462	Hair Diseases	3.5%
463	Hand Dermatoses	3.5%
464	Infant, Premature, Diseases	3.5%
465	keratoacanthoma	3.5%
466	Keratosis	3.5%
467	Nail Diseases	3.5%
468	Photosensitivity Disorders	3.5%
469	Prurigo	3.5%
470	Pyoderma	3.5%
471	Rosacea	3.5%
472	Sebaceous Gland Diseases	3.5%
473	Skin Diseases, Vesiculobullous	3.5%
474	Skin Ulcer	3.5%
475	Sweat Gland Diseases	3.5%
476	Skin Diseases, Papulosquamous	3.5%
477	Skin Diseases, Vascular	3.5%
478	Acneiform Eruptions	3.5%
479	Infantile Colic	3.5%
480	Ocular Rosacea	3.5%
481	Subcorneal pustular dermatosis	3.5%
482	Erythematotelangiectatic Rosacea	3.5%
483	Papulopustular Rosacea	3.5%
484	Chronic Actinic Dermatitis	3.5%
485	Medial Tibial Stress Syndrome	3.5%
486	Ainhum	3.4%
487	Airway Obstruction	3.4%
488	Bunion	3.4%
489	Choking	3.4%
490	Cochlear Diseases	3.4%
491	Dermatitis Herpetiformis	3.4%
492	Dysostoses	3.4%
493	Epiglottitis	3.4%
494	Fibrodysplasia Ossificans Progressiva	3.4%
495	Hemoptysis	3.4%
496	Chronic Obstructive Airway Disease	3.4%
497	Mediastinitis	3.4%
498	Middle Lobe Syndrome	3.4%
499	Myoglobinuria	3.4%
500	Myositis Ossificans	3.4%
501	Otitis Externa	3.4%
502	Otitis Media	3.4%
503	Spinal Stenosis	3.4%
504	Spondylosis	3.4%
505	Tenosynovitis	3.4%
506	Vestibular Diseases	3.4%
507	Intervertebral Disc Degeneration	3.4%
508	Mitochondrial Myopathies	3.4%
509	Endolymphatic Hydrops	3.4%
510	Acute Lung Injury	3.4%
511	Sacroiliitis	3.4%
512	Muscle Cramp	3.4%
513	Pertussis	3.4%
514	Eosinophilia-Myalgia Syndrome	3.4%
515	Dysacusis	3.4%
516	Sebaceous Gland Neoplasms	3.4%
517	Foot Ulcer	3.4%
518	Muscle Rigidity	3.4%
519	Muscle Spasticity	3.4%
520	Cogwheel Rigidity	3.4%
521	Nuchal Rigidity	3.4%
522	Long QT Syndrome	3.4%
523	Tricuspid Atresia	3.4%
524	Arrhythmogenic Right Ventricular Dysplasia	3.4%
525	Behcet Syndrome	3.4%
526	Gonadal Dysgenesis	3.4%
527	Adrenogenital Syndrome	3.4%
528	Ovotesticular Disorders of Sex Development	3.4%
529	Dermatitis, Photoallergic	3.4%
530	Angioedemas, Hereditary	3.2%
531	Palatal Neoplasms	3.2%
532	Hypokalemic periodic paralysis	3.2%
533	Aortopulmonary Septal Defect	3.2%
534	Double Outlet Right Ventricle	3.2%
535	Endocardial Cushion Defects	3.2%
536	Myocardial bridging	3.2%
537	Aorticopulmonary Septal Defect	3.2%
538	Chronic Fatigue Syndrome	3.1%
539	Acoustic Neuroma	3.1%
540	Giant Cell Epulis	3.1%
541	Muscle Weakness	3.1%
542	Neoplastic Syndromes, Hereditary	3.1%
543	Porphyrias, Hepatic	3.1%
544	Musculoskeletal Pain	3%
545	Pseudohypoparathyroidism	3%
546	Herpes Zoster Oticus	3%
547	Arthralgia	3%
548	Polyarthralgia	3%
549	Anemia, Sickle Cell	3%
550	Thalassemia	3%
551	Skin Diseases, Infectious	3%
552	Skin Neoplasms	3%
553	Pigmentation Disorders	3%
554	Vestibulocochlear Nerve Diseases	3%
555	Anemia, Neonatal	3%
556	Arthritis, Infectious	3%
557	Lipomatosis	3%
558	Mediastinal Cyst	3%
559	Pelger-Huet Anomaly	3%
560	Pericardial Cyst	3%
561	Pruritus	3%
562	Thymic Cyst	3%
563	Erythema	3%
564	Werner Syndrome	3%
565	Necrolytic Migratory Erythema	3%
566	Cutaneous Fistula	3%
567	Myasthenic Syndromes, Congenital	3%
568	Nephrogenic Fibrosing Dermopathy	3%
569	Nephrogenic Systemic Fibrosis	3%
570	Urticaria Pigmentosa	3%
571	Umbilical hernia	2.9%
572	Anterior Compartment Syndrome	2.9%
573	Histiocytosis, Langerhans-Cell	2.9%
574	Mediastinal Emphysema	2.9%
575	Osteomyelitis	2.9%
576	Osteoporosis	2.9%
577	Periostitis	2.9%
578	Enthesopathy	2.9%
579	Bone Demineralization, Pathologic	2.9%
580	Post-Traumatic Osteoporosis	2.9%
581	Arthritis, Experimental	2.9%
582	Abdominal Compartment Syndrome	2.9%
583	Pulmonary Aspergillosis	2.9%
584	Bronchopulmonary Aspergillosis	2.9%
585	Hypoventilation	2.9%
586	Acidosis, Respiratory	2.9%
587	Alkalosis, Respiratory	2.9%
588	Alveolar Bone Loss	2.9%
589	Femur Head Necrosis	2.9%
590	Sarcoidosis, Pulmonary	2.9%
591	Sleep Apnea Syndromes	2.9%
592	Polymyositis	2.9%
593	Osteolysis	2.9%
594	Pulmonary Infarction	2.9%
595	Dermatitis, Irritant	2.9%
596	Acne Conglobata	2.9%
597	Chondrodysplasia Punctata	2.9%
598	Enchondromatosis	2.9%
599	Lordosis	2.9%
600	Meniere Disease	2.9%
601	Osteosclerosis	2.9%
602	Otitis Media with Effusion	2.9%
603	Pulmonary Emphysema	2.9%
604	Spondylolysis	2.9%
605	kyphosis	2.9%
606	Kashin-Beck Disease	2.9%
607	Truncus Arteriosus, Persistent	2.8%
608	Romano-Ward Syndrome	2.8%
609	Toxic Epidermal Necrolysis	2.7%
610	Stevens-Johnson Syndrome	2.7%
611	Myalgia	2.7%
612	Erythema Infectiosum	2.7%
613	Exanthema Subitum	2.7%
614	Neonatal Abstinence Syndrome	2.6%
615	Erythema Nodosum	2.6%
616	Hip Dislocation	2.6%
617	Dermatitis, Occupational	2.6%
618	Shoulder Dislocation	2.6%
619	Hip Dysplasia	2.6%
620	Fetal Growth Retardation	2.6%
621	Mastocytosis	2.6%
622	Fetal Hypoxia	2.6%
623	Congenital nystagmus	2.6%
624	Orbital Myositis	2.6%
625	Fetal Alcohol Spectrum Disorders	2.6%
626	Melorheostosis	2.6%
627	Osteopetrosis	2.6%
628	Spondylolisthesis	2.6%
629	Toxoplasmosis, Congenital	2.6%
630	Dyspnea, Paroxysmal	2.6%
631	Respiratory Paralysis	2.6%
632	Syphilis, Congenital	2.6%
633	Pyomyositis	2.6%
634	Granulomatosis with polyangiitis	2.5%
635	Acromegaly	2.5%
636	Joint Tuberculosis	2.5%
637	Tuberculosis, Osteoarticular	2.5%
638	Bone Tuberculosis	2.5%
639	Dermatitis, Allergic Contact	2.5%
640	Hyperacusis	2.5%
641	Tinnitus	2.5%
642	Phonophobia	2.5%
643	Hearing Loss	2.5%
644	Rett Syndrome	2.5%
645	Lupus Vasculitis, Central Nervous System	2.5%
646	Lemierre Syndrome	2.5%
647	Wiskott-Aldrich Syndrome	2.5%
648	Vestibular Neuronitis	2.4%
649	Osteoporosis, Postmenopausal	2.4%
650	Tinea Capitis	2.4%
651	Onychomycosis	2.4%
652	Sleep Apnea, Obstructive	2.4%
653	Sleep Apnea, Central	2.4%
654	Diaper Rash	2.4%
655	Peutz-Jeghers Syndrome	2.4%
656	Ecthyma	2.4%
657	Autoimmune Lymphoproliferative Syndrome	2.3%
658	Anhidrosis	2.3%
659	Cholesteatoma	2.3%
660	Pressure Ulcer	2.3%
661	Folliculitis	2.3%
662	Foot Dermatoses	2.3%
663	Gynecomastia	2.3%
664	Hypertrichosis	2.3%
665	Hypohidrosis	2.3%
666	Hypotrichosis	2.3%
667	Leg Ulcer	2.3%
668	Miliaria	2.3%
669	Parakeratosis	2.3%
670	Parapsoriasis	2.3%
671	Familial Mediterranean Fever	2.3%
672	Pityriasis	2.3%
673	Psoriasis	2.3%
674	Sweet Syndrome	2.3%
675	Hidradenitis	2.3%
676	Onycholysis	2.3%
677	Miliaria Rubra	2.3%
678	Hyperpigmentation	2.3%
679	Lichenoid Eruptions	2.3%
680	Chloracne	2.3%
681	Congenital Hyperinsulinism	2.3%
682	Arteriovenous fistula	2.3%
683	Chorioamnionitis	2.3%
684	Anti-Glomerular Basement Membrane Disease	2.3%
685	Adrenoleukodystrophy	2.3%
686	Rickets	2.3%
687	Variegate Porphyria	2.2%
688	Acute intermittent porphyria	2.2%
689	Porphyria Cutanea Tarda	2.2%
690	Shoulder Pain	2.2%
691	Sickle Cell Trait	2.2%
692	Neuronal Ceroid-Lipofuscinoses	2.2%
693	Vertigo	2.1%
694	Transfusion-Related Acute Lung Injury	2.1%
695	Invasive Pulmonary Aspergillosis	2.1%
696	Deafness	2.1%
697	Hearing Loss, Sudden	2.1%
698	Hearing Loss, Bilateral	2.1%
699	Hearing Loss, High-Frequency	2.1%
700	Hearing Loss, Mixed Conductive-Sensorineural	2.1%
701	Hearing Loss, Unilateral	2.1%
702	Complete Hearing Loss	2.1%
703	Deaf Mutism	2.1%
704	Hepatolenticular Degeneration	2.1%
705	Fabry Disease	2.1%
706	Denys-Drash Syndrome	2%
707	Mitochondrial Encephalomyopathies	2%
708	Hidradenitis Suppurativa	2%
709	Acantholysis	2%
710	Breast Cyst	2%
711	Actinic keratosis	2%
712	Paralysis, Obstetric	2%
713	Pemphigoid, Benign Mucous Membrane	2%
714	Pemphigus	2%
715	Piedra	2%
716	Retinopathy of Prematurity	2%
717	Sunburn	2%
718	Amino Acid Metabolism, Inborn Errors	2%
719	Argyria	2%
720	Carbohydrate Metabolism, Inborn Errors	2%
721	Hirsutism	2%
722	Lactation Disorder	2%
723	Mastitis	2%
724	Metal Metabolism, Inborn Errors	2%
725	Progeria	2%
726	Urticaria	2%
727	Lysosomal Storage Diseases	2%
728	Cytochrome-c Oxidase Deficiency	2%
729	Peroxisomal Disorders	2%
730	Adiposis Dolorosa	2%
731	Pruritus Vulvae	2%
732	Mastocytoma	1.9%
733	Pruritus Ani	1.9%
734	Amyloid Neuropathies, Familial	1.9%
735	Erythema Chronicum Migrans	1.9%
736	Glycogen storage disease type II	1.9%
737	MELAS Syndrome	1.9%
738	Osteomalacia	1.9%
739	Tinea Pedis	1.8%
740	Ophthalmia Neonatorum	1.8%
741	Hydrops Fetalis	1.8%
742	Familial Hypophosphatemic Rickets	1.8%
743	Galactosemias	1.8%
744	Urea Cycle Disorders, Inborn	1.8%
745	Tyrosinemias	1.8%
746	Dermatomycoses	1.7%
747	Mucocutaneous Lymph Node Syndrome	1.7%
748	Skin Diseases, Bacterial	1.7%
749	Retinitis Pigmentosa	1.7%
750	Pigmentary retinopathy	1.7%
751	Lichen Planus	1.7%
752	Melanosis	1.7%
753	Chloasma	1.7%
754	Pityriasis Rosea	1.7%
755	Pityriasis Rubra Pilaris	1.7%
756	Vitiligo	1.7%
757	Lichen Nitidus	1.7%
758	Drug Eruptions	1.7%
759	Lipodystrophy	1.7%
760	Livedo Reticularis	1.7%
761	Malignant Atrophic Papulosis	1.7%
762	Ataxia Telangiectasia	1.7%
763	Chronic granulomatous disease	1.7%
764	Polyarteritis Nodosa	1.7%
765	Takayasu Arteritis	1.7%
766	Mycetoma	1.7%
767	Optic Atrophy, Hereditary, Leber	1.7%
768	Hyperphosphaturia	1.7%
769	Canavan Disease	1.7%
770	Alexander Disease	1.7%
771	Gaucher Disease	1.6%
772	Duane Retraction Syndrome	1.5%
773	Auditory Perceptual Disorders	1.5%
774	Leigh Disease	1.5%
775	Thrombasthenia	1.5%
776	Antithrombin III Deficiency	1.5%
777	Protein C Deficiency	1.5%
778	Brain Diseases, Metabolic, Inborn	1.5%
779	Afibrinogenemia	1.5%
780	Dystonia Musculorum Deformans	1.5%
781	Factor VII Deficiency	1.5%
782	Factor X Deficiency	1.5%
783	Factor XII Deficiency	1.5%
784	Hemophilia A	1.5%
785	Leukomalacia, Periventricular	1.5%
786	Activated Protein C Resistance	1.5%
787	Factor II deficiency	1.5%
788	Factor VIII Deficiency	1.5%
789	Factor V deficiency	1.5%
790	Factor XI Deficiency	1.5%
791	Hypoprothrombinemias	1.5%
792	Radicular Cyst	1.5%
793	Fanconi Anemia	1.5%
794	Nesidioblastosis	1.5%
795	Lafora Disease	1.5%
796	Unverricht-Lundborg Syndrome	1.5%
797	Anemia, Diamond-Blackfan	1.5%
798	Alopecia	1.5%
799	Sweating, Gustatory	1.5%
800	Androgenetic Alopecia	1.5%
801	Auriculotemporal Syndrome	1.5%
802	Lice Infestations	1.5%
803	Varicose Ulcer	1.5%
804	Breast Neoplasms, Male	1.5%
805	Triple Negative Breast Neoplasms	1.5%
806	Alkaptonuria	1.5%
807	Glycogen Storage Disease	1.5%
808	Hypophosphatasia	1.5%
809	Propionic acidemia	1.5%
810	Dihydropyrimidine Dehydrogenase Deficiency	1.5%
811	Galactorrhea	1.5%
812	Cystinosis	1.5%
813	Tay-Sachs Disease	1.4%
814	Acanthosis Nigricans	1.4%
815	Alopecia Areata	1.4%
816	Lentigo	1.4%
817	Multiple Endocrine Neoplasia	1.4%
818	Renal Osteodystrophy	1.4%
819	Renal rickets	1.4%
820	Niemann-Pick Disease, Type C	1.4%
821	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.4%
822	Larva Migrans	1.3%
823	Leishmaniasis	1.3%
824	Molluscum Contagiosum	1.3%
825	Angioedema	1.3%
826	Onchocerciasis	1.3%
827	Chromoblastomycosis	1.3%
828	Dermatophytosis	1.3%
829	Sporotrichosis	1.3%
830	Tinea	1.3%
831	Tinea Versicolor	1.3%
832	Trichophytosis	1.3%
833	Hyalohyphomycosis	1.3%
834	Hypolipoproteinemias	1.3%
835	Acute Generalized Exanthematous Pustulosis	1.3%
836	Hyperlipidemia, Familial Combined	1.3%
837	Hyperlipoproteinemia Type III	1.3%
838	Kernicterus	1.2%
839	Lichen Planus, Oral	1.2%
840	Glycogen Storage Disease Type I	1.2%
841	Glycogen Storage Disease Type V	1.2%
842	Warts	1.1%
843	Candidiasis, Chronic Mucocutaneous	1.1%
844	Cutaneous Candidiasis	1.1%
845	Erysipelas	1.1%
846	Lactose Intolerance	1.1%
847	Serum Sickness	1.1%
848	Staphylococcal Skin Infections	1.1%
849	Erythrasma	1.1%
850	Carcinoma, Lobular	1.1%
851	Hyperhomocysteinemia	1.1%
852	Huntington Disease	1.1%
853	Renal Aminoacidurias	1.1%
854	Fanconi Syndrome	1.1%
855	Pseudohypoaldosteronism	1.1%
856	Liddle Syndrome	1.1%
857	Hyperlipoproteinemia Type IV	1.1%
858	Hyperlipoproteinemia Type V	1.1%
859	Giant Cell Arteritis	1.1%
860	Temporal Arteritis	1.1%
861	Kearns-Sayre syndrome	1.1%
862	Leishmaniasis, Cutaneous	1.1%
863	Eczema Herpeticum	1.1%
864	Fusariosis	1.1%
865	Hypoalphalipoproteinemias	1%
866	Nephroblastoma	1%
867	Multiple Endocrine Neoplasia Type 1	1%
868	Friedreich Ataxia	1%
869	Renal tubular acidosis	1%
870	Adenomatous Polyposis Coli	0.9%
871	Hereditary Angioedema Type III	0.9%
872	Hereditary Angioedema Types I and II	0.9%
873	Epidermodysplasia Verruciformis	0.9%
874	Herpes Labialis	0.9%
875	Diabetic Foot	0.9%
876	Staphylococcal Scalded Skin Syndrome	0.9%
877	Cystinuria	0.9%
878	HIV-Associated Lipodystrophy Syndrome	0.9%
879	Condylomata Acuminata	0.8%
880	Furunculosis	0.8%
881	furuncle	0.8%
882	Impetigo	0.8%
883	carbuncle	0.8%
884	Glycosuria, Renal	0.8%

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