MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Ketoacidosis

(UMLS:C0220982)

UMLS ID:: C0220982
MeSH ID:: D007662

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.452.076.176.652

Synonym(s)

Ketoacidosis

KETO ACIDOSIS

KETOACIDOSIS

Ketoacidosis, NOS

keto acidosis

ketoacidosis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Quetiapine Fumarate	FAERS: 1152	US FAERS
2	Canagliflozin	FAERS: 483 Canada Vigilance: 7	Canada Vigilance US FAERS
3	empagliflozin	FAERS: 230 Canada Vigilance: 3	Canada Vigilance US FAERS
4	2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol	FAERS: 153 Canada Vigilance: 7	Canada Vigilance US FAERS
5	Insulin Glargine	FAERS: 63 Canada Vigilance: 2	Canada Vigilance US FAERS
6	Olanzapine	FAERS: 51 Canada Vigilance: 8	Canada Vigilance SIDER US FAERS
7	Metformin	FAERS: 38	SIDER US FAERS
8	Synjardy	FAERS: 20	US FAERS
9	Aripiprazole	FAERS: 19	US FAERS
10	insulin glulisine	FAERS: 16 Canada Vigilance: 1	Canada Vigilance US FAERS
11	Metformin	FAERS: 15	US FAERS
12	Dapagliflozin and metformin hydrochloride	FAERS: 14	US FAERS
13	Nadolol	FAERS: 12	US FAERS
14	Clozapine	FAERS: 11 Canada Vigilance: 2	Canada Vigilance SIDER US FAERS
15	Sertraline	FAERS: 9	US FAERS
16	Insulin	FAERS: 7	US FAERS
17	Risperidone	FAERS: 7 Canada Vigilance: 1	Canada Vigilance US FAERS
18	Glyxambi	FAERS: 6	US FAERS
19	Propranolol	FAERS: 6	US FAERS
20	Exenatide	FAERS: 5	US FAERS
21	Invokamet	FAERS: 5	US FAERS
22	Gatifloxacin	FAERS: 4	US FAERS
23	Sitagliptin Phosphate	FAERS: 4	US FAERS
24	Varenicline	FAERS: 4	US FAERS
25	Dimethyl Fumarate	FAERS: 3 Canada Vigilance: 1	Canada Vigilance US FAERS
26	Docetaxel	FAERS: 3	US FAERS
27	Duloxetine Hydrochloride	FAERS: 3	US FAERS
28	Liraglutide	FAERS: 3	US FAERS
29	Mycophenolic Acid	FAERS: 3	US FAERS
30	Pregabalin	FAERS: 3	US FAERS
31	Qtern	FAERS: 3	US FAERS
32	Rosuvastatin Calcium	FAERS: 3	US FAERS
33	Tacrolimus	FAERS: 3	US FAERS
34	Zonisamide	FAERS: 3	US FAERS
35	desloratadine	FAERS: 3	US FAERS
36	insulin aspart, insulin aspart protamine drug combination 30:70	FAERS: 3	US FAERS
37	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	FAERS: 2	US FAERS
38	Cinacalcet	FAERS: 2	US FAERS
39	Dexamethasone	FAERS: 2	US FAERS
40	Gabapentin	FAERS: 2	US FAERS
41	Insulin Lispro	FAERS: 2	US FAERS
42	Insulin degludec	FAERS: 2	US FAERS
43	Insulin	FAERS: 2	US FAERS
44	Leuprolide	FAERS: 2	US FAERS
45	Prednisolone	FAERS: 2	US FAERS
46	Propranolol	FAERS: 2	US FAERS
47	Rivaroxaban	FAERS: 2	US FAERS
48	Topiramate	FAERS: 2	US FAERS
49	pasireotide	FAERS: 2	US FAERS
50	ziprasidone	FAERS: 2	US FAERS
51	Acetaminophen	FAERS: 1	US FAERS
52	Axitinib	FAERS: 1	US FAERS
53	Bosentan	FAERS: 1	US FAERS
54	Ceftazidime	FAERS: 1	US FAERS
55	Cetirizine	FAERS: 1	US FAERS
56	Citalopram	FAERS: 1	US FAERS
57	Diphenoxylate	FAERS: 1	US FAERS
58	Erlotinib Hydrochloride	FAERS: 1	US FAERS
59	Fluorescein	FAERS: 1	US FAERS
60	Fluticasone-Salmeterol Drug Combination	FAERS: 1	US FAERS
61	Fluvastatin	FAERS: 1	US FAERS
62	Guanfacine	FAERS: 1	US FAERS
63	Imiquimod	FAERS: 1	US FAERS
64	Insulin Detemir	FAERS: 1	US FAERS
65	Insulin Lispro	FAERS: 1	US FAERS
66	Isotretinoin	FAERS: 1	US FAERS
67	Jentadueto	FAERS: 1	US FAERS
68	Kombiglyze XR	FAERS: 1	US FAERS
69	Letrozole	FAERS: 1	US FAERS
70	Linagliptin	FAERS: 1	US FAERS
71	Lisdexamfetamine Dimesylate	FAERS: 1	US FAERS
72	Lopinavir	FAERS: 1	US FAERS
73	Lurasidone Hydrochloride	FAERS: 1	US FAERS
74	Mesalamine	FAERS: 1	US FAERS
75	Norethindrone acetate and ethinyl estradiol	FAERS: 1	US FAERS
76	Oseltamivir	FAERS: 1	US FAERS
77	PCI 32765	FAERS: 1	US FAERS
78	Paliperidone Palmitate	FAERS: 1	US FAERS
79	Paliperidone Palmitate	FAERS: 1	US FAERS
80	Paroxetine	FAERS: 1	US FAERS
81	Quetiapine Fumarate	FAERS: 1	US FAERS
82	Rivastigmine	FAERS: 1	US FAERS
83	Rosiglitazone	FAERS: 1	US FAERS
84	Triumeq	FAERS: 1	US FAERS
85	Viekira Pak	FAERS: 1	US FAERS
86	Zoledronic Acid	FAERS: 1	US FAERS
87	ambrisentan	FAERS: 1	US FAERS
88	apremilast	FAERS: 1	US FAERS
89	caffeine citrate	FAERS: 1	US FAERS
90	glimepiride	FAERS: 1	US FAERS
91	hydrocortisone hemisuccinate	FAERS: 1	US FAERS
92	iopromide	FAERS: 1	US FAERS
93	miglitol	FAERS: 1	US FAERS
94	mirabegron	FAERS: 1	US FAERS
95	pimecrolimus	FAERS: 1	US FAERS
96	semaglutide	FAERS: 1 Canada Vigilance: 2	Canada Vigilance US FAERS
97	sofosbuvir-velpatasvir drug combination	FAERS: 1	US FAERS
98	treprostinil	FAERS: 1	US FAERS
99	Arsenicals		SIDER
100	Diazoxide		SIDER
101	Octreotide	Canada Vigilance: 1	Canada Vigilance
102	Pentamidine		SIDER
103	Saquinavir		SIDER
104	palbociclib	Canada Vigilance: 1	Canada Vigilance

Similar ADE(s)

	Name	Semantic Similarity
1	Acidosis, Lactic	48.4%
2	Alkalosis	34.4%
3	Acidosis, Respiratory	32.6%
4	Calcium Metabolism Disorders	25.4%
5	Iron Metabolism Disorders	25.4%
6	Phosphorus Metabolism Disorders	25.4%
7	Water-Electrolyte Imbalance	25.4%
8	Lipid Metabolism Disorders	25.4%
9	Mitochondrial Diseases	25.4%
10	Glucose Metabolism Disorders	25.4%
11	Achlorhydria	23.1%
12	Wasting Syndrome	23%
13	Hypercalcemia	19.8%
14	Hypocalcemia	19.8%
15	Milk-Alkali Syndrome	19.8%
16	Renal tubular acidosis	19.3%
17	Osteopenia	17.2%
18	Brain Diseases, Metabolic	16.9%
19	Nutrition Disorders	16.4%
20	Alkalosis, Respiratory	15.2%
21	Lipodystrophy	14.9%
22	Amyloidosis	14.8%
23	Calcinosis	14.8%
24	Hyperglycemia	14.8%
25	Hyperinsulinism	14.8%
26	Hyperkalemia	14.8%
27	Hypernatremia	14.8%
28	Hypoglycemia	14.8%
29	Hypokalemia	14.8%
30	Hyponatremia	14.8%
31	Xanthomatosis	14.8%
32	Hypophosphatemia	14.8%
33	Dyslipidemias	14.8%
34	Iron Overload	14.8%
35	Xanthoma	14.8%
36	Pseudohypoparathyroidism	13.1%
37	Rickets	12.6%
38	Brain Diseases, Metabolic, Inborn	11.8%
39	Diabetes Mellitus	10.6%
40	Hyperhomocysteinemia	10.5%
41	Leigh Disease	10.3%
42	Dehydration	10.1%
43	Lipomatosis	10.1%
44	Water Intoxication	10.1%
45	Werner Syndrome	10.1%
46	Amino Acid Metabolism, Inborn Errors	9.9%
47	Bloom Syndrome	9.9%
48	Carbohydrate Metabolism, Inborn Errors	9.9%
49	Metal Metabolism, Inborn Errors	9.9%
50	Osteoporosis	9.9%
51	Progeria	9.9%
52	Lysosomal Storage Diseases	9.9%
53	Bone Demineralization, Pathologic	9.9%
54	Cytochrome-c Oxidase Deficiency	9.9%
55	Peroxisomal Disorders	9.9%
56	Post-Traumatic Osteoporosis	9.9%
57	Celiac Disease	9.8%
58	Sprue, Tropical	9.8%
59	Steatorrhea	9.8%
60	Sprue	9.8%
61	Lactose Intolerance	9.7%
62	Calciphylaxis	9.7%
63	Hemosiderosis	9.7%
64	Hypolipoproteinemias	9.7%
65	Vascular calcification	9.7%
66	Carbamoyl-Phosphate Synthase I Deficiency Disease	9%
67	Hyperlipoproteinemia Type IV	8.6%
68	Hyperlipoproteinemia Type V	8.6%
69	Child Nutrition Disorders	8.5%
70	Hypervitaminosis A	8.5%
71	Infant Nutrition Disorders	8.5%
72	Malnutrition	8.5%
73	Hyperlipidemia, Familial Combined	8.4%
74	Osteomalacia	8.4%
75	Smith-Lemli-Opitz Syndrome	8.3%
76	Galactosemias	8.3%
77	Urea Cycle Disorders, Inborn	8.3%
78	Tyrosinemias	8.3%
79	Mitochondrial Encephalomyopathies	8.2%
80	Congenital Hyperinsulinism	8.1%
81	Hyperlipoproteinemia Type III	7.8%
82	Mitochondrial Myopathies	7.6%
83	Myelinolysis, Central Pontine	7.5%
84	Glycosuria	7.4%
85	Reye Syndrome	7.4%
86	Hepatic Encephalopathy	7.3%
87	Hyperphosphaturia	7.2%
88	Hypercholesterolemia	7.2%
89	Hyperlipoproteinemias	7.2%
90	Hypertriglyceridemia	7.2%
91	Hypoalphalipoproteinemias	7.2%
92	Familial Hypophosphatemic Rickets	6.8%
93	Homocystinuria	6.7%
94	HIV Wasting Syndrome	6.5%
95	Adiposis Dolorosa	6.5%
96	Alkaptonuria	6.5%
97	Glycogen Storage Disease	6.5%
98	Hypophosphatasia	6.5%
99	Insulin Resistance	6.5%
100	Osteoporosis, Postmenopausal	6.5%
101	Propionic acidemia	6.5%
102	Dihydropyrimidine Dehydrogenase Deficiency	6.5%
103	Cystinosis	6.5%
104	Glycogen storage disease type II	6.4%
105	Gaucher Disease	6.2%
106	Amyloid Neuropathies, Familial	6.1%
107	Porphyrias, Hepatic	6%
108	Necrobiosis Lipoidica Diabeticorum	5.9%
109	Fanconi Anemia	5.8%
110	Nesidioblastosis	5.8%
111	Neuronal Ceroid-Lipofuscinoses	5.7%
112	HIV-Associated Lipodystrophy Syndrome	5.5%
113	Wernicke Encephalopathy	5.5%
114	Zellweger Syndrome	5.3%
115	Renal Osteodystrophy	5.3%
116	Renal rickets	5.3%
117	MELAS Syndrome	5.3%
118	Menkes Kinky Hair Syndrome	5.3%
119	Adrenoleukodystrophy	5.1%
120	Gestational Diabetes	5.1%
121	Latent Autoimmune Diabetes in Adults	5.1%
122	Tay-Sachs Disease	5.1%
123	Diabetes Mellitus, Experimental	5%
124	Niemann-Pick Disease, Type C	4.9%
125	Deficiency Diseases	4.9%
126	Starvation	4.9%
127	Refeeding Syndrome	4.9%
128	Hepatolenticular Degeneration	4.9%
129	Nephrocalcinosis	4.9%
130	Tetany	4.9%
131	Diabetic Ketoacidosis	4.9%
132	Friedreich Ataxia	4.9%
133	Refsum Disease	4.8%
134	Glycosuria, Renal	4.8%
135	Cerebral Amyloid Angiopathy	4.8%
136	Glycogen Storage Disease Type I	4.8%
137	Glycogen Storage Disease Type V	4.8%
138	Mucopolysaccharidosis III	4.8%
139	Fabry Disease	4.8%
140	Kernicterus	4.3%
141	Cockayne Syndrome	4.2%
142	Familial Periodic Paralysis	4%
143	Primary amyloidosis	3.9%
144	Kearns-Sayre syndrome	3.9%
145	Variegate Porphyria	3.9%
146	Acute intermittent porphyria	3.9%
147	Porphyria Cutanea Tarda	3.9%
148	Renal Aminoacidurias	3.9%
149	Fanconi Syndrome	3.9%
150	Pseudohypoaldosteronism	3.9%
151	Liddle Syndrome	3.9%
152	Ataxia Telangiectasia	3.8%
153	Optic Atrophy, Hereditary, Leber	3.7%
154	Sjogren-Larsson Syndrome	3.4%
155	Xeroderma Pigmentosum	3.3%
156	Gout	3.3%
157	Amyotrophic Lateral Sclerosis	3.3%
158	Antley-Bixler Syndrome Phenotype	3.2%
159	Canavan Disease	3.2%
160	Alexander Disease	3.2%
161	Kwashiorkor	3.2%
162	Magnesium Deficiency	3.2%
163	Potassium Deficiency	3.2%
164	Protein Deficiency	3.2%
165	Avitaminosis	3.2%
166	Mucopolysaccharidosis II	3.2%
167	Hypokalemic periodic paralysis	2.9%
168	Frontotemporal dementia	2.9%
169	Cystinuria	2.9%
170	CREST Syndrome	2.8%
171	Albinism	2.5%
172	Arthritis, Gouty	2.4%
173	Ascorbic Acid Deficiency	2.4%
174	Vitamin A Deficiency	2.4%
175	Vitamin D Deficiency	2.4%
176	Vitamin E Deficiency	2.4%
177	Marasmus	2.4%
178	Folic Acid Deficiency	2%
179	Pellagra	2%
180	Thiamine Deficiency	2%
181	Vitamin B 12 Deficiency	2%
182	Vitamin B 6 Deficiency	2%
183	Pyridoxine Deficiency	2%
184	Ichthyosis, X-Linked	2%
185	Obesity	1.9%
186	Beriberi	1.8%
187	Obesity, Abdominal	1.6%
188	Pediatric Obesity	1.3%
189	Vitamin K Deficiency	1.2%
190	Anemia, Pernicious	1.2%
191	Prader-Willi Syndrome	1.1%
192	Scurvy	1%
193	Subacute Combined Degeneration	0.6%

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