MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Fascioliasis

(UMLS:C0015652)

Definition:: Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.
UMLS ID:: C0015652
MeSH ID:: D005211

Classification 1:

Name:

Parasitic Diseases
MeSH Tree Number(s):: C03.335.865.354|C03.518.424

Classification 2:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.552.664.424

Synonym(s)

Fascioliasis

Fasciola; infestation

Fasciolosis

Infection by Fasciola

Infection by Fasciola, NOS

Infection caused by Fasciola

fascioliasis

fasciolosis

infestation; Distoma hepaticum

10.

infestation; Fasciola

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1		US FAERS
2	telithromycin	FAERS: 1		US FAERS
3	Triclabendazole		12113760	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Echinococcosis, Hepatic	40.7%
2	Liver Abscess, Amebic	33.6%
3	Opisthorchiasis	28.8%
4	Schistosomiasis	28.8%
5	Helminthiasis, Animal	23.3%
6	Cestode Infections	22.4%
7	Nematode infections	22.4%
8	Schistosomiasis japonica	21.8%
9	Schistosomiasis mansoni	21.8%
10	Protozoan Infections	19.6%
11	Toxocariasis	19.1%
12	Dirofilariasis	18.6%
13	Intestinal Diseases, Parasitic	18.3%
14	Larva Migrans	18.1%
15	Giardiasis	17.7%
16	Cryptosporidiosis	17.6%
17	Strongyle Infections, Equine	16.8%
18	Protozoan Infections, Animal	16.3%
19	Parasitic Diseases, Animal	16.2%
20	Fatty Liver	15.5%
21	Hepatitis	15.5%
22	Portal Hypertension	15.5%
23	Liver Cirrhosis	15.5%
24	Focal Nodular Hyperplasia	15.5%
25	Hepatic Insufficiency	15.5%
26	Steatohepatitis	15.5%
27	Pregnancy Complications, Parasitic	15.5%
28	Parasitemia	15.3%
29	Diphyllobothriasis	15.3%
30	Echinococcosis	15.3%
31	Hymenolepiasis	15.3%
32	Secernentea Infections	15.3%
33	Biliary cirrhosis	14.8%
34	Babesiosis	14.4%
35	Onchocerciasis	14%
36	Liver neoplasms	13.8%
37	Leishmaniasis	13.6%
38	Opportunistic Infections	13.4%
39	Fatty Liver, Alcoholic	13.4%
40	Hepatitis, Alcoholic	13.4%
41	Liver Cirrhosis, Alcoholic	13.4%
42	Hepatic Veno-Occlusive Disease	12.5%
43	Peliosis Hepatis	12.5%
44	Hepatopulmonary Syndrome	12.5%
45	Hepatomegaly	12.3%
46	Hepatic Vein Thrombosis	12.2%
47	Liver Abscess	12.2%
48	Budd-Chiari Syndrome	12.2%
49	Neurocysticercosis	12.2%
50	Amebiasis	12.1%
51	Coccidiosis	12.1%
52	Malaria	12.1%
53	Acanthamoeba Infection	12.1%
54	Trichomonas Infections	12.1%
55	Ciliophora Infections	12.1%
56	Balamuthia Infection	12.1%
57	Cysticercosis	11.8%
58	Sparganosis	11.8%
59	Ascaridida Infections	11.8%
60	Oxyurida Infections	11.8%
61	Acanthamoeba Keratitis	11.7%
62	Malaria, Cerebral	11.1%
63	Esophageal and Gastric Varices	10.8%
64	Helminthiasis	10.7%
65	Chemical and Drug Induced Liver Injury	10.5%
66	Hepatitis, Chronic	10.2%
67	Hepatorenal Syndrome	10.2%
68	Liver Failure	10.2%
69	Non-alcoholic Fatty Liver Disease	10.2%
70	Chronic active hepatitis	10.2%
71	Ascariasis	10%
72	Filariasis	10%
73	Gnathostomiasis	10%
74	Hookworm Infections	10%
75	Oxyuriasis	10%
76	Strongyloidiasis	10%
77	Trichinellosis	10%
78	Trichostrongyloidiasis	10%
79	Leishmaniasis, Cutaneous	10%
80	Loiasis	9.2%
81	Enterobiasis	9.2%
82	Biliary Tract Diseases	8.9%
83	Gastrointestinal Diseases	8.9%
84	Pancreatic Diseases	8.9%
85	Porphyrias, Hepatic	8.7%
86	Entamoebiasis	8.5%
87	Malaria, Falciparum	8.5%
88	Malaria, Vivax	8.5%
89	Mite Infestations	8.5%
90	Myiasis	8.5%
91	Tick Infestations	8.5%
92	Toxoplasmosis	8.5%
93	Trypanosomiasis	8.5%
94	Isosporiasis	8.5%
95	Hepatitis, Animal	8.5%
96	Hepatitis, Viral, Human	8.5%
97	Liver Cirrhosis, Experimental	8.1%
98	Superinfection	8%
99	Hepatitis B, Chronic	7.8%
100	Hepatitis C, Chronic	7.8%
101	Hepatocellular Adenoma	7.6%
102	Liver Failure, Acute	7.6%
103	End Stage Liver Disease	7.6%
104	Zollinger-Ellison syndrome	7.2%
105	Digestive System Neoplasms	7.1%
106	Liver Diseases, Parasitic	7.1%
107	Gastrointestinal Neoplasms	6.9%
108	Trematode Infections	6.9%
109	Pancreatic Fistula	6.9%
110	Fascioliasis	6.8%
111	Chemical and Drug Induced Liver Injury, Chronic	6.7%
112	Blackwater Fever	6.7%
113	Hypodermyiasis	6.7%
114	Leishmaniasis, Visceral	6.7%
115	Liver Neoplasms, Experimental	6.7%
116	African Trypanosomiasis	6.7%
117	Chagas Disease	6.7%
118	Lice Infestations	6.7%
119	Reye Syndrome	6.7%
120	Trichomonas Vaginitis	6.7%
121	Massive Hepatic Necrosis	6.3%
122	Autoimmune hepatitis	6.1%
123	AIDS-Related Opportunistic Infections	5.9%
124	Toxoplasmosis, Cerebral	5.9%
125	Peritoneal Neoplasms	5.9%
126	Mesenteric vascular insufficiency	5.7%
127	Bile Duct Neoplasms	5.7%
128	gallbladder neoplasm	5.7%
129	Intestinal Neoplasms	5.7%
130	Stomach Neoplasms	5.7%
131	Variegate Porphyria	5.7%
132	Acute intermittent porphyria	5.7%
133	Porphyria Cutanea Tarda	5.7%
134	Esophageal Atresia	5.7%
135	Intestinal Atresia	5.7%
136	Mesenteric Vascular Occlusion	5.7%
137	Intestinal Fistula	5.6%
138	Enterocutaneous Fistula	5.6%
139	Proctocolitis	5.5%
140	Colorectal Neoplasms	5.5%
141	Dysentery	5.4%
142	Enteritis	5.4%
143	Enterocolitis	5.4%
144	Esophagitis	5.4%
145	Gastritis	5.4%
146	Inflammatory Bowel Diseases	5.4%
147	Cholecystolithiasis	5.4%
148	Hepatitis, Viral, Animal	5.3%
149	Bile Duct Diseases	5.2%
150	Cholelithiasis	5.2%
151	Chylous Ascites	5.2%
152	Esophageal Diseases	5.2%
153	Gastroenteritis	5.2%
154	Intestinal Diseases	5.2%
155	Pancreatic Insufficiency	5.2%
156	Pancreatic Neoplasm	5.2%
157	Pancreatitis	5.2%
158	Pneumoperitoneum	5.2%
159	Stomach Diseases	5.2%
160	Hepatitis E	5.1%
161	Hepatitis B	5.1%
162	Hepatitis C	5.1%
163	Hepatitis A	5.1%
164	Esophageal Neoplasms	5%
165	Hepatic Encephalopathy	5%
166	Duodenitis	5%
167	Ileitis	5%
168	Erosive Duodenitis	5%
169	Cecal Neoplasms	4.9%
170	Duodenal Neoplasms	4.9%
171	Choledochal Cyst	4.9%
172	Rectal Fistula	4.7%
173	Anal Fistula	4.7%
174	Colitis	4.7%
175	Duodenogastric Reflux	4.7%
176	Peptic Ulcer	4.7%
177	Proctitis	4.7%
178	Choledocholithiasis	4.7%
179	Chagas Cardiomyopathy	4.7%
180	Zellweger Syndrome	4.6%
181	Toxoplasmosis, Congenital	4.5%
182	Gastrointestinal Stromal Tumors	4.5%
183	Hepatolenticular Degeneration	4.3%
184	Pancreatic Cyst	4.2%
185	Anus Neoplasms	4.1%
186	Sigmoid Neoplasms	4.1%
187	Anus, Imperforate	4.1%
188	Gastrointestinal Hemorrhage	4.1%
189	Hemoperitoneum	4.1%
190	Mesenteric Panniculitis	4.1%
191	Panniculitis, Peritoneal	4.1%
192	Peritonitis	4.1%
193	Pouchitis	4.1%
194	Peritoneal Fibrosis	4.1%
195	Encapsulating Peritoneal Sclerosis	4.1%
196	Anorectal Malformations	4.1%
197	Biliary Fistula	4.1%
198	Gastric Fistula	4.1%
199	Appendiceal Neoplasms	4.1%
200	Colonic Neoplasms	4.1%
201	Rectal Neoplasms	4.1%
202	Tuberculosis, Gastrointestinal	4.1%
203	Crohn Disease	4%
204	Duodenal Obstruction	4%
205	Enterocolitis, Neutropenic	4%
206	Necrotizing Enterocolitis	4%
207	Appendicitis	3.9%
208	Duodenal Ulcer	3.7%
209	Peptic Ulcer Perforation	3.7%
210	Gastric ulcer	3.7%
211	Adenomatous Polyposis Coli	3.5%
212	Cecal Diseases	3.4%
213	Cholangitis	3.4%
214	Cholecystitis	3.4%
215	Cholestasis	3.4%
216	Colonic Diseases	3.4%
217	Common Bile Duct Diseases	3.4%
218	Esophageal Stenosis	3.4%
219	Ileal Diseases	3.4%
220	Intestinal Obstruction	3.4%
221	Intestinal Perforation	3.4%
222	Jejunal Diseases	3.4%
223	Pneumatosis Cystoides Intestinalis	3.4%
224	Rectal Diseases	3.4%
225	Gastric Dilatation	3.4%
226	Pancreatitis, Chronic	3.4%
227	Gastric outlet obstruction	3.4%
228	Cronkhite-Canada Syndrome	3.4%
229	Intestinal Polyposis	3.4%
230	Enterocolitis, Pseudomembranous	3.3%
231	pseudomembranous colitis	3.3%
232	Dysentery, Bacillary	3.3%
233	Colonic Pseudo-Obstruction	3.1%
234	Colitis, Ischemic	3.1%
235	Cystic Fibrosis	3%
236	Congenital Hyperinsulinism	2.9%
237	Rift Valley Fever	2.8%
238	Esophageal Perforation	2.8%
239	Barrett Esophagus	2.7%
240	Deglutition Disorders	2.7%
241	Achlorhydria	2.7%
242	Pancreatic Pseudocyst	2.7%
243	Gastric Antral Vascular Ectasia	2.7%
244	Peptic Ulcer Hemorrhage	2.7%
245	Gastroparesis	2.7%
246	Pancreatitis, Alcoholic	2.7%
247	Carcinoma, Pancreatic Ductal	2.6%
248	Cholestasis, Extrahepatic	2.5%
249	Biliary Dyskinesia	2.5%
250	Cholangitis, Sclerosing	2.5%
251	Colonic Diseases, Functional	2.5%
252	Esophageal motility disorders	2.5%
253	Fecal Incontinence	2.5%
254	Fecal Impaction	2.5%
255	Intussusception	2.5%
256	Mallory-Weiss Syndrome	2.5%
257	Megacolon	2.5%
258	Pyloric Stenosis	2.5%
259	Acalculous Cholecystitis	2.5%
260	Ileus	2.5%
261	Meconium ileus	2.5%
262	Melena	2.3%
263	Hematemesis	2.2%
264	insulinoma	2.2%
265	Gastrinoma	2.2%
266	Glucagonoma	2.2%
267	Esophageal Achalasia	2.1%
268	Anal Fissure	2.1%
269	Intestinal Pseudo-Obstruction	2.1%
270	Irritable Bowel Syndrome	2.1%
271	Superior Mesenteric Artery Syndrome	2.1%
272	Emphysematous Cholecystitis	2.1%
273	Neurogenic Bowel	2.1%
274	Sphincter of Oddi Dysfunction	2.1%
275	Anal Ulcer	2.1%
276	Hemorrhoids	2%
277	Afferent Loop Syndrome	2%
278	Celiac Disease	2%
279	Short Bowel Syndrome	2%
280	Sprue, Tropical	2%
281	Steatorrhea	2%
282	Rectocele	2%
283	Sprue	2%
284	Diverticulitis	2%
285	Dumping Syndrome	2%
286	Rectal Prolapse	2%
287	Vipoma	2%
288	Nesidioblastosis	1.9%
289	Diverticulum	1.7%
290	Diverticulosis	1.7%
291	Pruritus Ani	1.7%
292	Laryngopharyngeal Reflux	1.5%
293	Peutz-Jeghers Syndrome	1.4%
294	Lactose Intolerance	1.4%
295	CREST Syndrome	0.9%

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