MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hypodontia

(UMLS:C0020608)

UMLS ID:: C0020608
MeSH ID:: D000848

Classification 1:

Name:

Stomatognathic Diseases
MeSH Tree Number(s):: C07.650.800.100|C07.793.700.100

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.850.800.100

Synonym(s)

Hypodontia

Failure of development of between one and six teeth

Oligodontia

Partial anodontia

Partial congenital absence of teeth

hypodontia

oligodontia

partial congenital absence of teeth

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Doxorubicin	FAERS: 1	US FAERS
2	Mebendazole	FAERS: 1	US FAERS
3	Phenytoin	FAERS: 1	US FAERS
4	Ribavirin		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Dental Enamel Hypoplasia	51.6%
2	Mouth Abnormalities	32.2%
3	Maxillofacial Abnormalities	24.3%
4	Tooth Loss	21.5%
5	Macrostomia	20.9%
6	Microstomia	20.9%
7	Bruxism	20.2%
8	Dental Leakage	20.2%
9	Hypercementosis	20.2%
10	Malocclusion	20.2%
11	Tooth Crowding	20.2%
12	Tooth Discoloration	20.2%
13	Tooth Demineralization	20.2%
14	Tooth Ankylosis	20.2%
15	Cleft Palate	19.6%
16	Mouth Diseases	17.4%
17	Jaw Abnormalities	17.2%
18	Tooth Injuries	16.8%
19	Tooth Resorption	16.3%
20	Toothache	15.9%
21	Jaw Diseases	14.4%
22	Pharyngeal Diseases	14.4%
23	Retrognathia	13.8%
24	Dental caries	13.2%
25	Dental Plaque	13.2%
26	Dental Pulp Calcification	13.2%
27	Pulpitis	13.2%
28	Tooth Erosion	13.2%
29	Abnormalities, Drug-Induced	12.6%
30	Situs Inversus	12.6%
31	Prognathism	12.5%
32	Micrognathism	12.4%
33	Pierre Robin Syndrome	12.4%
34	Beckwith-Wiedemann Syndrome	11.6%
35	Wolf-Hirschhorn Syndrome	11.6%
36	Facial Hemiatrophy	11.2%
37	Melkersson-Rosenthal Syndrome	11.2%
38	Temporomandibular Joint Disorders	11.1%
39	Holoprosencephaly	10.9%
40	Tooth Avulsion	10.7%
41	Dental Pulp Necrosis	10.6%
42	Mobius Syndrome	10.5%
43	Eye Abnormalities	10.5%
44	Cardiovascular Abnormalities	10.5%
45	Skin Abnormalities	10.2%
46	Lymphatic Abnormalities	10.2%
47	Congenital Microtia	10.2%
48	Burning Mouth Syndrome	10.1%
49	Lip Diseases	10.1%
50	Microglossia	10.1%
51	Oral Submucous Fibrosis	10.1%
52	Periodontal Diseases	10.1%
53	Salivary Gland Diseases	10.1%
54	Stomatitis	10.1%
55	Tongue Diseases	10.1%
56	Oral Ulcer	10.1%
57	Aicardi's syndrome	10.1%
58	Smith-Magenis syndrome	10%
59	Congenital diaphragmatic hernia	10%
60	Cri-du-Chat Syndrome	9.9%
61	Down Syndrome	9.9%
62	Trisomy 21	9.9%
63	Bell Palsy	9.6%
64	Rubinstein-Taybi Syndrome	8.9%
65	Sleep Bruxism	8.8%
66	Salivary Gland Fistula	8.8%
67	Salivary Gland Neoplasms	8.8%
68	Tongue Neoplasms	8.8%
69	Urogenital Abnormalities	8.8%
70	Ectodermal Dysplasia	8.7%
71	Aplasia Cutis Congenita	8.7%
72	Tooth Diseases	8.7%
73	Giant Cell Epulis	8.7%
74	Prader-Willi Syndrome	8.6%
75	Parotid Neoplasms	8.4%
76	Anencephaly	8.2%
77	Facial Nerve Diseases	8.2%
78	Maxillary Diseases	8.2%
79	Granulomatosis, Orofacial	8.2%
80	Oral candidiasis	8.1%
81	Mouth Neoplasms	8.1%
82	Oral Fistula	8.1%
83	Lichen Planus, Oral	8%
84	Gingival Recession	7.8%
85	Parotitis	7.8%
86	Gingival Atrophy	7.8%
87	Genetic Diseases, Inborn	7.8%
88	CHARGE Syndrome	7.8%
89	Radicular Cyst	7.7%
90	Gingival Hemorrhage	7.7%
91	Prune Belly Syndrome	7.4%
92	Twins, Conjoined	7.4%
93	Waardenburg Syndrome	7.4%
94	Dural Arteriovenous Fistula	7.1%
95	Dextrocardia	7.1%
96	Kartagener Syndrome	6.9%
97	Pharyngitis	6.9%
98	Nail-Patella Syndrome	6.8%
99	Marfan Syndrome	6.7%
100	Xeroderma	6.7%
101	Facial paralysis	6.7%
102	Facial Paresis	6.7%
103	Nasopharyngitis	6.6%
104	Cheilitis	6.6%
105	Drooling	6.6%
106	Gingival Diseases	6.6%
107	Glossitis	6.6%
108	Macroglossia	6.6%
109	Periodontitis	6.6%
110	Sialadenitis	6.6%
111	Sialometaplasia, Necrotizing	6.6%
112	Sialorrhea	6.6%
113	Aphthous Stomatitis	6.6%
114	Xerostomia	6.6%
115	Glossoptosis	6.6%
116	Hemifacial Spasm	6.6%
117	Peri-Implantitis	6.6%
118	Fetal Diseases	6.3%
119	Temporomandibular Joint Dysfunction Syndrome	6.2%
120	Abnormalities, Radiation-Induced	6.2%
121	Anophthalmos	6%
122	Anus, Imperforate	6%
123	Hydranencephaly	6%
124	Microphthalmos	6%
125	Neural Tube Defects	6%
126	Tethered Cord Syndrome	6%
127	Iniencephaly	6%
128	Craniorachischisis	6%
129	Limb Deformities, Congenital	6%
130	Exencephaly	6%
131	Septo-Optic Dysplasia	6%
132	Craniofacial Abnormalities	6%
133	Cortical Dysplasia	6%
134	Malformations of Cortical Development	6%
135	Anorectal Malformations	6%
136	Bloom Syndrome	6%
137	Nasopharyngeal Neoplasms	5.9%
138	Pharyngeal Neoplasms	5.8%
139	Palatal Neoplasms	5.8%
140	Scimitar Syndrome	5.6%
141	Polycystic Kidney Diseases	5.6%
142	Williams Syndrome	5.6%
143	Behcet Syndrome	5.5%
144	Cockayne Syndrome	5.5%
145	Facial Neuralgia	5.3%
146	Dental Fistula	5.3%
147	Oroantral Fistula	5.3%
148	Alstrom Syndrome	5.2%
149	Retinal Dysplasia	5.1%
150	Blepharophimosis	5.1%
151	Laryngostenosis	5.1%
152	Aniridia	5.1%
153	Esophageal Atresia	5%
154	Intestinal Atresia	5%
155	Horseshoe Kidney	5%
156	Pectus excavatum	5%
157	Klippel-Feil Syndrome	5%
158	Gastroschisis	5%
159	Synostosis	5%
160	Epidermolysis Bullosa	5%
161	Acrodermatitis	5%
162	Lymphangiectasis, Intestinal	5%
163	Gianotti-Crosti Syndrome	5%
164	Cystic Fibrosis	4.9%
165	Basal Cell Nevus Syndrome	4.9%
166	Gingivitis	4.9%
167	Glossitis, Benign Migratory	4.9%
168	Pericoronitis	4.9%
169	Aggressive Periodontitis	4.9%
170	Gingival Overgrowth	4.9%
171	Craniosynostosis	4.9%
172	Syndactyly	4.9%
173	Brachycephaly	4.9%
174	Microcephaly	4.9%
175	Macrocephaly	4.9%
176	Fragile X Syndrome	4.9%
177	Smith-Lemli-Opitz Syndrome	4.7%
178	Ichthyosis, X-Linked	4.6%
179	Vesicular Stomatitis	4.5%
180	Primary Ciliary Dyskinesia	4.5%
181	Acrocephalosyndactylia	4.4%
182	Noonan Syndrome	4.4%
183	Tonsillitis	4.4%
184	Hypodontia	4.4%
185	Lemierre Syndrome	4.4%
186	Arthrogryposis	4.4%
187	Choanal Atresia	4.4%
188	Tracheobronchomegaly	4.4%
189	Laryngocele	4.4%
190	Choledochal Cyst	4.3%
191	Hermaphroditism	4.3%
192	Disorders of Sex Development	4.3%
193	Cryptorchidism	4.3%
194	Hypospadias	4.3%
195	Central Nervous System Cysts	4.3%
196	Dandy-Walker Syndrome	4.3%
197	Meconium Aspiration Syndrome	4.3%
198	Turner Syndrome	4.2%
199	POEMS Syndrome	4.2%
200	Abdominal Cramps	4.2%
201	Amniotic Band Syndrome	4.2%
202	Asphyxia Neonatorum	4.2%
203	Infant, Premature, Diseases	4.2%
204	Infantile Colic	4.2%
205	Porencephaly	4.2%
206	Classical Lissencephalies and Subcortical Band Heterotopias	4.1%
207	Gingival Hyperplasia	4.1%
208	Gingival Hypertrophy	4.1%
209	Pseudoxanthoma Elasticum	4%
210	Alveolar Bone Loss	3.9%
211	Amelia	3.9%
212	Arachnodactyly	3.9%
213	Ectopia Cordis	3.9%
214	Ectromelia	3.9%
215	Hemimelia	3.9%
216	Meningomyelocele	3.9%
217	Phocomelia	3.9%
218	Sirenomelia	3.9%
219	Spina Bifida	3.9%
220	Polydactyly	3.9%
221	Brachydactyly	3.9%
222	Plagiocephaly	3.9%
223	Lower Extremity Deformities, Congenital	3.9%
224	Upper Extremity Deformities, Congenital	3.9%
225	Single umbilical artery	3.9%
226	Trigeminal Nerve Disorder	3.9%
227	Nasopharyngeal carcinoma	3.9%
228	Laryngomalacia	3.8%
229	Herpes Zoster Oticus	3.8%
230	Pectus carinatum	3.8%
231	Leukoplakia, Oral	3.8%
232	Retropharyngeal Abscess	3.8%
233	Hypopharyngeal Neoplasms	3.8%
234	Hypopharyngeal Cancer	3.8%
235	Bladder Exstrophy	3.7%
236	Epispadias	3.7%
237	Herpes Labialis	3.7%
238	Multicystic Dysplastic Kidney	3.7%
239	Polycystic Kidney, Autosomal Dominant	3.7%
240	Sjogren-Larsson Syndrome	3.7%
241	Xeroderma Pigmentosum	3.6%
242	Poland Syndrome	3.6%
243	Neoplastic Syndromes, Hereditary	3.5%
244	Kallmann Syndrome	3.5%
245	Klinefelter Syndrome	3.4%
246	Anemia, Neonatal	3.4%
247	Multiple Epiphyseal Dysplasia	3.4%
248	Osteochondrodysplasias	3.4%
249	Pelger-Huet Anomaly	3.4%
250	Persistent Fetal Circulation Syndrome	3.4%
251	Werner Syndrome	3.4%
252	Myasthenic Syndromes, Congenital	3.4%
253	Umbilical hernia	3.3%
254	Aortic coarctation	3.3%
255	Cor Triatriatum	3.3%
256	Coronary Vessel Anomalies	3.3%
257	Patent ductus arteriosus	3.3%
258	Ebstein Anomaly	3.3%
259	Heart Septal Defects	3.3%
260	Meningocele	3.3%
261	Tetralogy of Fallot	3.3%
262	Transposition of Great Vessels	3.3%
263	Hypoplastic Left Heart Syndrome	3.3%
264	May-Thurner Syndrome	3.3%
265	Encephalocele	3.3%
266	Facial Nerve Injuries	3.3%
267	Craniofacial Dysostosis	3.3%
268	Zellweger Syndrome	3.3%
269	Wolff-Parkinson-White Syndrome	3.3%
270	Charcot-Marie-Tooth Disease	3.3%
271	Antley-Bixler Syndrome Phenotype	3.3%
272	Mumps	3.2%
273	Trigeminal Neuralgia	3.2%
274	Hyperkeratosis, Epidermolytic	3.1%
275	Tuberous Sclerosis	3%
276	Dermal Sinus	2.9%
277	Spina Bifida Cystica	2.9%
278	Spina Bifida Occulta	2.9%
279	Lissencephaly	2.9%
280	Polymicrogyria	2.9%
281	Pachygyria	2.9%
282	Schizencephaly	2.9%
283	Periventricular Nodular Heterotopia	2.9%
284	Toxic Epidermal Necrolysis	2.9%
285	Stevens-Johnson Syndrome	2.9%
286	Dwarfism	2.9%
287	Neonatal Abstinence Syndrome	2.9%
288	Long QT Syndrome	2.8%
289	Platybasia	2.8%
290	Tricuspid Atresia	2.8%
291	Arrhythmogenic Right Ventricular Dysplasia	2.8%
292	Anemia, Sickle Cell	2.8%
293	Thalassemia	2.8%
294	Gonadal Dysgenesis	2.8%
295	Bronchomalacia	2.8%
296	Adrenogenital Syndrome	2.8%
297	Tracheomalacia	2.8%
298	Ovotesticular Disorders of Sex Development	2.8%
299	Muscular Dystrophy, Duchenne	2.8%
300	Fetal Growth Retardation	2.8%
301	Peritonsillar Abscess	2.8%
302	Tonsillar Neoplasms	2.8%
303	Muscular Dystrophy	2.8%
304	Osteogenesis Imperfecta	2.8%
305	Refsum Disease	2.8%
306	Fetal Hypoxia	2.8%
307	Congenital nystagmus	2.8%
308	Fetal Alcohol Spectrum Disorders	2.8%
309	Toxoplasmosis, Congenital	2.8%
310	Ulcerative stomatitis	2.7%
311	Syphilis, Congenital	2.7%
312	Albinism	2.6%
313	Hyperandrogenism	2.6%
314	Familial Mediterranean Fever	2.5%
315	Aortopulmonary Septal Defect	2.4%
316	Double Outlet Right Ventricle	2.4%
317	Endocardial Cushion Defects	2.4%
318	Myocardial bridging	2.4%
319	Aorticopulmonary Septal Defect	2.4%
320	Autoimmune Lymphoproliferative Syndrome	2.4%
321	Congenital Hyperinsulinism	2.4%
322	Chorioamnionitis	2.4%
323	Angioedemas, Hereditary	2.4%
324	Wiskott-Aldrich Syndrome	2.2%
325	Sicca Syndrome	2.2%
326	Sjogren's Syndrome	2.2%
327	Rett Syndrome	2.2%
328	Mandibulofacial Dysostosis	2.1%
329	Romano-Ward Syndrome	2.1%
330	Mucopolysaccharidosis II	2%
331	Truncus Arteriosus, Persistent	2%
332	Goldenhar Syndrome	2%
333	Paralysis, Obstetric	2%
334	Retinopathy of Prematurity	2%
335	Menkes Kinky Hair Syndrome	2%
336	Amino Acid Metabolism, Inborn Errors	2%
337	Carbohydrate Metabolism, Inborn Errors	2%
338	Metal Metabolism, Inborn Errors	2%
339	Progeria	2%
340	Lysosomal Storage Diseases	2%
341	Cytochrome-c Oxidase Deficiency	2%
342	Peroxisomal Disorders	2%
343	Bronchopulmonary Dysplasia	2%
344	Myotonic Dystrophy	2%
345	Sickle Cell Trait	1.9%
346	Neuronal Ceroid-Lipofuscinoses	1.8%
347	Ophthalmia Neonatorum	1.8%
348	Talipes	1.8%
349	Respiratory Distress Syndrome, Newborn	1.7%
350	Cutis Laxa	1.7%
351	Ataxia Telangiectasia	1.7%
352	Retinitis Pigmentosa	1.7%
353	Pigmentary retinopathy	1.7%
354	Porokeratosis	1.7%
355	Keratoderma, Palmoplantar	1.7%
356	Chronic granulomatous disease	1.6%
357	Hepatolenticular Degeneration	1.6%
358	Welander Distal Myopathy	1.6%
359	Arteriovenous fistula	1.6%
360	Amyloid Neuropathies, Familial	1.6%
361	Adrenoleukodystrophy	1.6%
362	Congenital clubfoot	1.6%
363	Vertical Talus	1.6%
364	Hydrops Fetalis	1.5%
365	Acute Chest Syndrome	1.5%
366	Duane Retraction Syndrome	1.4%
367	Galactosemias	1.4%
368	Urea Cycle Disorders, Inborn	1.4%
369	Tyrosinemias	1.4%
370	Fabry Disease	1.4%
371	Porphyrias, Hepatic	1.4%
372	Peutz-Jeghers Syndrome	1.4%
373	Myotonia Congenita	1.4%
374	Thrombasthenia	1.4%
375	Antithrombin III Deficiency	1.4%
376	Protein C Deficiency	1.4%
377	Brain Diseases, Metabolic, Inborn	1.4%
378	Afibrinogenemia	1.4%
379	Dystonia Musculorum Deformans	1.4%
380	Factor VII Deficiency	1.4%
381	Factor X Deficiency	1.4%
382	Factor XII Deficiency	1.4%
383	Hemophilia A	1.4%
384	Leukomalacia, Periventricular	1.4%
385	Activated Protein C Resistance	1.4%
386	Factor II deficiency	1.4%
387	Factor VIII Deficiency	1.4%
388	Factor V deficiency	1.4%
389	Factor XI Deficiency	1.4%
390	Hypoprothrombinemias	1.4%
391	Fanconi Anemia	1.4%
392	Nesidioblastosis	1.4%
393	Lafora Disease	1.4%
394	Unverricht-Lundborg Syndrome	1.4%
395	Anemia, Diamond-Blackfan	1.4%
396	Denys-Drash Syndrome	1.4%
397	Canavan Disease	1.3%
398	Alexander Disease	1.3%
399	Glycogen storage disease type II	1.3%
400	Alkaptonuria	1.3%
401	Glycogen Storage Disease	1.3%
402	Hypophosphatasia	1.3%
403	Propionic acidemia	1.3%
404	Dihydropyrimidine Dehydrogenase Deficiency	1.3%
405	Cystinosis	1.3%
406	Optic Atrophy, Hereditary, Leber	1.3%
407	Hyperphosphaturia	1.3%
408	Multiple Endocrine Neoplasia	1.3%
409	Congenital Hypothyroidism	1.3%
410	Dermatitis, Atopic	1.2%
411	Mucopolysaccharidosis III	1.2%
412	Homocystinuria	1.1%
413	Leigh Disease	1.1%
414	Kernicterus	1.1%
415	Hyaline Membrane Disease	1.1%
416	Hypolipoproteinemias	1.1%
417	Papillon-Lefevre Disease	1.1%
418	Hyperlipidemia, Familial Combined	1.1%
419	Hyperlipoproteinemia Type III	1.1%
420	Gaucher Disease	1%
421	Huntington Disease	1%
422	Glycogen Storage Disease Type I	1%
423	Glycogen Storage Disease Type V	1%
424	Carbamoyl-Phosphate Synthase I Deficiency Disease	1%
425	Familial Periodic Paralysis	0.9%
426	Lactose Intolerance	0.9%
427	Variegate Porphyria	0.9%
428	Acute intermittent porphyria	0.9%
429	Porphyria Cutanea Tarda	0.9%
430	Hyperhomocysteinemia	0.9%
431	Renal Aminoacidurias	0.9%
432	Fanconi Syndrome	0.9%
433	Pseudohypoaldosteronism	0.9%
434	Liddle Syndrome	0.9%
435	Hyperlipoproteinemia Type IV	0.9%
436	Hyperlipoproteinemia Type V	0.9%
437	Nephroblastoma	0.9%
438	Tay-Sachs Disease	0.8%
439	Gout	0.8%
440	Niemann-Pick Disease, Type C	0.8%
441	Multiple Endocrine Neoplasia Type 1	0.8%
442	Pseudohypoparathyroidism	0.8%
443	Friedreich Ataxia	0.8%
444	Adenomatous Polyposis Coli	0.8%
445	Renal tubular acidosis	0.8%
446	Hypoalphalipoproteinemias	0.8%
447	Hypokalemic periodic paralysis	0.7%
448	Cystinuria	0.7%
449	Glycosuria, Renal	0.6%
450	Familial Hypophosphatemic Rickets	0.6%
451	Arthritis, Gouty	0.6%
452	MELAS Syndrome	0.5%

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