MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Melena

(UMLS:C0025222)

Definition:: The black, tarry, foul-smelling FECES that contain degraded blood.
UMLS ID:: C0025222
MeSH ID:: D008551

Classification 1:

Name:

Fluids and Secretions
MeSH Tree Number(s):: A12.459.764

Classification 2:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405.227.600

Classification 3:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.414.788.600

Synonym(s)

Melena

Altered blood in stool

Altered blood passed per rectum

BLACK STOOL

Black stools

Black, tarry stool

Dark stools

MELAENA

MELENA

10.

Melaena

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Aspirin	8038346	CTD
2	Azathioprine	18431703	CTD
3	Cimetidine	85850 509014 6833524	CTD
4	Methotrexate	5108642	CTD
5	Penicillin V	22112502	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Peptic Ulcer Hemorrhage	38.7%
2	Hematemesis	33.1%
3	Postoperative Hemorrhage	20.1%
4	Shock, Hemorrhagic	20.1%
5	Zollinger-Ellison syndrome	18.7%
6	Hemoperitoneum	18.4%
7	Hematoma	17.6%
8	Exsanguination	17.6%
9	Proctocolitis	16.5%
10	Dysentery	16.1%
11	Enteritis	16.1%
12	Enterocolitis	16.1%
13	Esophagitis	16.1%
14	Gastritis	16.1%
15	Inflammatory Bowel Diseases	16.1%
16	Esophageal Diseases	15.4%
17	Gastroenteritis	15.4%
18	Intestinal Diseases	15.4%
19	Stomach Diseases	15.4%
20	Duodenitis	14.8%
21	Ileitis	14.8%
22	Erosive Duodenitis	14.8%
23	Hemarthrosis	14.3%
24	Hemothorax	14.3%
25	Retrobulbar Hemorrhage	14.3%
26	Colorectal Neoplasms	14.2%
27	Colitis	14%
28	Duodenogastric Reflux	14%
29	Peptic Ulcer	14%
30	Proctitis	14%
31	Uterine hemorrhage	14%
32	Eye Hemorrhage	13.9%
33	Polydipsia	13.8%
34	Gastrointestinal Neoplasms	13.7%
35	Hemoptysis	13.6%
36	Ecchymosis	13.4%
37	Petechiae	13.4%
38	Purpura	13.4%
39	Intestinal Neoplasms	13.3%
40	Stomach Neoplasms	13.3%
41	Ascites	12.8%
42	Fibrosis	12.8%
43	Gliosis	12.8%
44	Growth Disorders	12.8%
45	Hyperbilirubinemia	12.8%
46	Hyperplasia	12.8%
47	Hypomenorrhea	12.8%
48	Inflammation	12.8%
49	Intraoperative Complications	12.8%
50	Ischemia	12.8%
51	Lithiasis	12.8%
52	Malacoplakia	12.8%
53	Menstruation Disturbances	12.8%
54	Metaplasia	12.8%
55	Nerve Degeneration	12.8%
56	Ochronosis	12.8%
57	Polymenorrhea	12.8%
58	Postoperative Complications	12.8%
59	Sclerosis	12.8%
60	Shock	12.8%
61	Ulcer	12.8%
62	Hyperammonemia	12.8%
63	Hyperamylasemia	12.8%
64	Teratogenesis	12.8%
65	Cardiac Death	12.8%
66	Hypovolemia	12.8%
67	Hyperuricemia	12.8%
68	Leukoaraiosis	12.8%
69	Dysbacteriosis	12.8%
70	Delayed Graft Function	12.8%
71	Cirrhosis	12.8%
72	Neointima	12.8%
73	Dysbiosis	12.8%
74	Menorrhagia	12.7%
75	Cecal Neoplasms	12.3%
76	Duodenal Neoplasms	12.3%
77	Pouchitis	12.3%
78	Tuberculosis, Gastrointestinal	12.1%
79	Infarction	12.1%
80	Systemic Inflammatory Response Syndrome	12.1%
81	Afferent Loop Syndrome	12%
82	Short Bowel Syndrome	12%
83	Crohn Disease	11.9%
84	Duodenal Obstruction	11.9%
85	Enterocolitis, Neutropenic	11.9%
86	Necrotizing Enterocolitis	11.9%
87	Epistaxis	11.7%
88	Appendicitis	11.7%
89	Esophageal Neoplasms	11.7%
90	Hematuria	11.7%
91	Hematoma, Epidural, Spinal	11.7%
92	Vascular Remodeling	11.6%
93	Intestinal Fistula	11.2%
94	Enterocutaneous Fistula	11.2%
95	Rectal Fistula	11.1%
96	Anal Fistula	11.1%
97	Duodenal Ulcer	10.9%
98	Peptic Ulcer Perforation	10.9%
99	Gastric ulcer	10.9%
100	Anus Neoplasms	10.7%
101	Esophageal and Gastric Varices	10.7%
102	Sigmoid Neoplasms	10.7%
103	Extravasation of Diagnostic and Therapeutic Materials	10.6%
104	Neoplastic Processes	10.6%
105	Necrosis	10.3%
106	Granulomatosis, Orofacial	10.3%
107	Pigmentation Disorders	10.3%
108	Respiratory Aspiration	10.3%
109	Mesenteric vascular insufficiency	10.3%
110	Acantholysis	10.2%
111	Chromosome Aberrations	10.2%
112	Dehydration	10.2%
113	Granuloma	10.2%
114	Leukocytosis	10.2%
115	Pleocytosis	10.2%
116	Peritoneal Fibrosis	10.2%
117	Encapsulating Peritoneal Sclerosis	10.2%
118	Esophageal Atresia	10.2%
119	Intestinal Atresia	10.2%
120	Mesenteric Vascular Occlusion	10.2%
121	Hematoma, Subdural	10.1%
122	Hematoma, Epidural, Cranial	10.1%
123	Appendiceal Neoplasms	10.1%
124	Colonic Neoplasms	10.1%
125	Rectal Neoplasms	10.1%
126	Cecal Diseases	10.1%
127	Colonic Diseases	10.1%
128	Esophageal Stenosis	10.1%
129	Ileal Diseases	10.1%
130	Intestinal Obstruction	10.1%
131	Intestinal Perforation	10.1%
132	Jejunal Diseases	10.1%
133	Pneumatosis Cystoides Intestinalis	10.1%
134	Rectal Diseases	10.1%
135	Gastric Dilatation	10.1%
136	Gastric outlet obstruction	10.1%
137	Cronkhite-Canada Syndrome	10.1%
138	Intestinal Polyposis	10.1%
139	Dumping Syndrome	9.9%
140	Enterocolitis, Pseudomembranous	9.9%
141	pseudomembranous colitis	9.9%
142	Dysentery, Bacillary	9.9%
143	Hyphema	9.5%
144	Vitreous Hemorrhage	9.5%
145	Colonic Pseudo-Obstruction	9.4%
146	Gastroparesis	9.3%
147	Adenomatous Polyposis Coli	9.3%
148	Metrorrhagia	9.2%
149	Colitis, Ischemic	9.2%
150	Gastrointestinal Stromal Tumors	8.9%
151	Biliary Tract Diseases	8.8%
152	Liver diseases	8.8%
153	Pancreatic Diseases	8.8%
154	Purpura Fulminans	8.8%
155	Genomic Instability	8.8%
156	Hematoma, Subdural, Spinal	8.7%
157	Chromosomal Instability	8.7%
158	Esophageal Perforation	8.4%
159	Intestinal Diseases, Parasitic	8.4%
160	Azotemia	8.4%
161	Muscle Weakness	8.3%
162	Barrett Esophagus	8.2%
163	Deglutition Disorders	8.2%
164	Achlorhydria	8.1%
165	Gastric Antral Vascular Ectasia	8.1%
166	Incisional hernia	8.1%
167	jaundice	8.1%
168	Rectocele	8%
169	Signs and Symptoms	8%
170	Pathological Conditions, Anatomical	8%
171	Pancreatic Fistula	8%
172	Retinal Hemorrhage	8%
173	Sudden infant death syndrome	7.9%
174	Choroid Hemorrhage	7.9%
175	Diverticulum	7.8%
176	Diverticulosis	7.8%
177	Postpartum Hemorrhage	7.8%
178	Gingival Hemorrhage	7.7%
179	Subarachnoid Hemorrhage	7.7%
180	Cerebral Hemorrhage	7.7%
181	Acute Disease	7.6%
182	Acute-Phase Reaction	7.6%
183	Amenorrhea	7.6%
184	Chronic disease	7.6%
185	Critical Illness	7.6%
186	Sudden death	7.6%
187	Fat necrosis	7.6%
188	Gangrene	7.6%
189	Graft Occlusion, Vascular	7.6%
190	Granuloma, Plasma Cell	7.6%
191	Iatrogenic Disease	7.6%
192	Multiple Organ Failure	7.6%
193	Oligomenorrhea	7.6%
194	Premenstrual syndrome	7.6%
195	Recurrence	7.6%
196	Retrograde Degeneration	7.6%
197	Retroperitoneal fibrosis	7.6%
198	Serositis	7.6%
199	Subcutaneous Emphysema	7.6%
200	Surgical Wound Dehiscence	7.6%
201	Syndrome	7.6%
202	Wallerian Degeneration	7.6%
203	Pyogenic granuloma	7.6%
204	Disease Progression	7.6%
205	Seroma	7.6%
206	Premenstrual Tension	7.6%
207	Delayed Emergence from Anesthesia	7.6%
208	Infant Death	7.6%
209	Anastomotic Leak	7.6%
210	Intraoperative Awareness	7.6%
211	Hematoma, Subdural, Intracranial	7.5%
212	Hematoma, Subdural, Chronic	7.5%
213	Hematoma, Subdural, Acute	7.5%
214	Colonic Diseases, Functional	7.5%
215	Esophageal motility disorders	7.5%
216	Fecal Incontinence	7.5%
217	Fecal Impaction	7.5%
218	Intussusception	7.5%
219	Mallory-Weiss Syndrome	7.5%
220	Megacolon	7.5%
221	Pyloric Stenosis	7.5%
222	Ileus	7.5%
223	Meconium ileus	7.5%
224	Cardiotoxicity	7.4%
225	Pain, Postoperative	7.3%
226	Rectal Prolapse	7.3%
227	Postoperative Nausea and Vomiting	7.2%
228	Digestive System Neoplasms	7.1%
229	Dysmenorrhea	7%
230	Failed Back Surgery Syndrome	7%
231	Liver neoplasms	6.9%
232	Biliary Sludge	6.8%
233	Thrombocytopenic purpura	6.7%
234	Purpura, Hyperglobulinemic	6.6%
235	Asphyxia	6.3%
236	Granuloma, Respiratory Tract	6.3%
237	Shock, Traumatic	6.3%
238	Esophageal Achalasia	6.2%
239	Anal Fissure	6.2%
240	Intestinal Pseudo-Obstruction	6.2%
241	Irritable Bowel Syndrome	6.2%
242	Superior Mesenteric Artery Syndrome	6.2%
243	Neurogenic Bowel	6.2%
244	Anal Ulcer	6.2%
245	Disease susceptibility	6.1%
246	Fetal Death	6.1%
247	Foreign-Body Reaction	6.1%
248	Hepatomegaly	6.1%
249	Neoplasm Invasiveness	6.1%
250	Neoplasm Metastasis	6.1%
251	Neoplasm Recurrence, Local	6.1%
252	Postpericardiotomy Syndrome	6.1%
253	Prosthesis Failure	6.1%
254	Reperfusion Injury	6.1%
255	Injection Site Reaction	6.1%
256	Aseptic Necrosis of Bone	6.1%
257	Carcinogenesis	6.1%
258	Neurogenic Inflammation	6.1%
259	Perinatal death	6.1%
260	Infusion site reaction	6.1%
261	Nephrogenic Fibrosing Dermopathy	6.1%
262	Corneal Endothelial Cell Loss	6.1%
263	Vasoplegia	6.1%
264	Suppuration	6.1%
265	Nephrogenic Systemic Fibrosis	6.1%
266	Metastasis	6.1%
267	Hemorrhoids	6.1%
268	Sinus Arrhythmia	6%
269	Atrial Fibrillation	6%
270	Atrial Flutter	6%
271	Dental Pulp Necrosis	6%
272	Granuloma, Foreign-Body	6%
273	Mediastinal Emphysema	6%
274	Surgical Wound Infection	6%
275	Ventricular Fibrillation	6%
276	Ventricular Flutter	6%
277	Parasystole	6%
278	Paroxysmal atrial fibrillation	6%
279	Facies	6%
280	Bradycardia	6%
281	Embryo Loss	6%
282	Celiac Disease	6%
283	Sex Chromosome Aberrations	6%
284	Sprue, Tropical	6%
285	Steatorrhea	6%
286	Sprue	6%
287	No-Reflow Phenomenon	6%
288	Diverticulitis	6%
289	Peritoneal Neoplasms	5.9%
290	Biliary cirrhosis	5.8%
291	Endotoxic shock	5.8%
292	Septic Shock	5.8%
293	Toxic Shock Syndrome	5.8%
294	Bile Duct Neoplasms	5.7%
295	gallbladder neoplasm	5.7%
296	Chromosome Fragility	5.6%
297	Biliary Fistula	5.4%
298	Gastric Fistula	5.4%
299	Cholecystolithiasis	5.4%
300	Jaundice, Obstructive	5.3%
301	Drowning	5.2%
302	Pancreatic Neoplasm	5.2%
303	Bile Duct Diseases	5.1%
304	Cholelithiasis	5.1%
305	Chylous Ascites	5.1%
306	Fatty Liver	5.1%
307	Hepatitis	5.1%
308	Portal Hypertension	5.1%
309	Liver Cirrhosis	5.1%
310	Pancreatic Insufficiency	5.1%
311	Pancreatitis	5.1%
312	Pneumoperitoneum	5.1%
313	Focal Nodular Hyperplasia	5.1%
314	Hepatic Insufficiency	5.1%
315	Steatohepatitis	5.1%
316	Giardiasis	5.1%
317	Fetal Growth Retardation	5.1%
318	DNA Degradation, Necrotic	5.1%
319	Aneuploidy	5.1%
320	Polyploidy	5.1%
321	Microsatellite Instability	5.1%
322	Heart Block	5%
323	Tachycardia	5%
324	Tachyarrhythmia	5%
325	Cicatrix	5%
326	Tissue Adhesions	5%
327	Granuloma Annulare	5%
328	Chromosome Breakage	5%
329	Pruritus Ani	5%
330	Brain Death	5%
331	Shock, Cardiogenic	5%
332	Sick Sinus Syndrome	4.9%
333	Trisomy	4.9%
334	Purpura, Thrombotic Thrombocytopenic	4.9%
335	Choledochal Cyst	4.9%
336	Choledocholithiasis	4.7%
337	Laryngopharyngeal Reflux	4.5%
338	Fatty Liver, Alcoholic	4.4%
339	Hepatitis, Alcoholic	4.4%
340	Liver Cirrhosis, Alcoholic	4.4%
341	Giant Cell Epulis	4.4%
342	Waterhouse-Friderichsen Syndrome	4.3%
343	Peutz-Jeghers Syndrome	4.3%
344	Long QT Syndrome	4.3%
345	Asthenia	4.3%
346	Body Temperature Changes	4.3%
347	Calculi	4.3%
348	Cyanosis	4.3%
349	Edema	4.3%
350	Failure to Thrive	4.3%
351	Fatigue	4.3%
352	Feminization	4.3%
353	Fetal Distress	4.3%
354	Hernia	4.3%
355	Hypertrophy	4.3%
356	Motion Sickness	4.3%
357	Nails, Malformed	4.3%
358	polyps	4.3%
359	Rupture, Spontaneous	4.3%
360	Signs and Symptoms, Digestive	4.3%
361	Signs and Symptoms, Respiratory	4.3%
362	Skin Manifestations	4.3%
363	Chills	4.3%
364	Lassitude	4.3%
365	Enterocele	4.3%
366	Atheroma	4.3%
367	Pseudophakia	4.3%
368	Urological Manifestations	4.3%
369	Stenosis	4.3%
370	Facial asymmetry	4.3%
371	Mobility Limitation	4.3%
372	Somnolence	4.3%
373	Plaque, Amyloid	4.3%
374	Plaque, Atherosclerotic	4.3%
375	Liver Diseases, Parasitic	4.3%
376	Lactose Intolerance	4.2%
377	Micronuclei, Chromosome-Defective	4.2%
378	Hepatic Veno-Occlusive Disease	4.1%
379	Pancreatic Cyst	4.1%
380	Peliosis Hepatis	4.1%
381	Hepatopulmonary Syndrome	4.1%
382	Anus, Imperforate	4.1%
383	Mesenteric Panniculitis	4.1%
384	Panniculitis, Peritoneal	4.1%
385	Peritonitis	4.1%
386	Anorectal Malformations	4.1%
387	Cross Infection	4.1%
388	Retinal Neovascularization	4.1%
389	Septicemia	4.1%
390	Sepsis	4.1%
391	Hepatic Vein Thrombosis	4%
392	Liver Abscess	4%
393	Budd-Chiari Syndrome	4%
394	Abscess	4%
395	Empyema	4%
396	Femur Head Necrosis	4%
397	Fetal Resorption	4%
398	Lymphatic Metastasis	4%
399	Neoplasms, Unknown Primary	4%
400	Sudden Cardiac Death	4%
401	Leukemic Infiltration	4%
402	Premenstrual Dysphoric Disorder	4%
403	Choroidal Neovascularization	4%
404	Primary Graft Dysfunction	4%
405	Neoplasm Micrometastasis	4%
406	Autoimmune thrombocytopenia	4%
407	Immune thrombocytopenic purpura	4%
408	Cicatrix, Hypertrophic	4%
409	Sinus Arrest, Cardiac	4%
410	Subacute Combined Degeneration	3.8%
411	Hepatocellular Adenoma	3.8%
412	Basal Ganglia Hemorrhage	3.8%
413	Eosinophilic Granuloma	3.7%
414	Phantom pain	3.7%
415	Phantom Limb Pain	3.7%
416	Cyst	3.5%
417	Eye Manifestations	3.5%
418	Neurologic Manifestations	3.5%
419	Chemical and Drug Induced Liver Injury	3.5%
420	Leukoplakia	3.4%
421	Cardiac Output, High	3.4%
422	Myocardial Stunning	3.4%
423	Reticulocytosis	3.4%
424	Low Cardiac Output Syndrome	3.4%
425	Airway Remodeling	3.4%
426	Ventricular Remodeling	3.4%
427	Alopecia	3.4%
428	Intermittent Claudication	3.4%
429	Androgenetic Alopecia	3.4%
430	Hepatorenal Syndrome	3.4%
431	Cholangitis	3.4%
432	Cholecystitis	3.4%
433	Cholestasis	3.4%
434	Common Bile Duct Diseases	3.4%
435	Hepatitis, Chronic	3.4%
436	Liver Failure	3.4%
437	Pancreatitis, Chronic	3.4%
438	Non-alcoholic Fatty Liver Disease	3.4%
439	Chronic active hepatitis	3.4%
440	Cryptosporidiosis	3.4%
441	Kernicterus	3.4%
442	Liver Abscess, Amebic	3.4%
443	Liver Neoplasms, Experimental	3.3%
444	Abdominal Pain	3.3%
445	Renal Colic	3.3%
446	Keloid	3.3%
447	Monosomy	3.3%
448	Tetraploidy	3.3%
449	Stillbirth	3.3%
450	Adams-Stokes Syndrome	3.3%
451	Atrioventricular Block	3.3%
452	Bundle-Branch Block	3.3%
453	Atrial Premature Complexes	3.3%
454	Sinoatrial Block	3.3%
455	Tachycardia, Paroxysmal	3.3%
456	Supraventricular tachycardia	3.3%
457	Tachycardia, Ventricular	3.3%
458	Tachycardia, Reciprocating	3.3%
459	Putaminal Hemorrhage	3.1%
460	Viremia	3.1%
461	Parasitemia	3.1%
462	Cystic Fibrosis	3%
463	Porphyrias, Hepatic	2.9%
464	Congenital Hyperinsulinism	2.9%
465	Cellulitis	2.9%
466	Hypergammaglobulinemia	2.9%
467	Romano-Ward Syndrome	2.8%
468	Eye pain	2.8%
469	Hepatitis, Animal	2.8%
470	Hepatitis, Viral, Human	2.8%
471	Muscular Atrophy	2.8%
472	CREST Syndrome	2.7%
473	Liver Cirrhosis, Experimental	2.7%
474	Pancreatic Pseudocyst	2.7%
475	Pancreatitis, Alcoholic	2.7%
476	Carcinoma, Pancreatic Ductal	2.6%
477	Hepatitis B, Chronic	2.6%
478	Hepatitis C, Chronic	2.6%
479	Granuloma, Laryngeal	2.6%
480	Anorexia	2.5%
481	Anoxia	2.5%
482	Bacteremia	2.5%
483	Constipation	2.5%
484	Diarrhea	2.5%
485	Dyspepsia	2.5%
486	Eructation	2.5%
487	Fever	2.5%
488	Flatulence	2.5%
489	Flushing	2.5%
490	Halitosis	2.5%
491	Heartburn	2.5%
492	Diaphragmatic Hernia	2.5%
493	Hiccough	2.5%
494	Hypercalciuria	2.5%
495	Hypercapnia	2.5%
496	Hyperphagia	2.5%
497	Intestinal Polyps	2.5%
498	Nausea	2.5%
499	Pallor	2.5%
500	Psychophysiologic Disorders	2.5%
501	Splenomegaly	2.5%
502	Vomiting	2.5%
503	Hypocapnia	2.5%
504	Dyschezia	2.5%
505	Hypoxia	2.5%
506	Hyperoxia	2.5%
507	Lower Urinary Tract Symptoms	2.5%
508	Hypoxemia	2.5%
509	Urinoma	2.5%
510	Cell Transformation, Viral	2.5%
511	Cholestasis, Extrahepatic	2.5%
512	Biliary Dyskinesia	2.5%
513	Cholangitis, Sclerosing	2.5%
514	Myocardial Reperfusion Injury	2.5%
515	Liver Failure, Acute	2.5%
516	Acalculous Cholecystitis	2.5%
517	End Stage Liver Disease	2.5%
518	Fungemia	2.5%
519	Tachycardia, Atrioventricular Nodal Reentry	2.5%
520	Tachycardia, Ectopic Atrial	2.5%
521	Tachycardia, Ectopic Junctional	2.5%
522	Sinus Tachycardia	2.5%
523	Torsades de Pointes	2.5%
524	Accelerated Idioventricular Rhythm	2.5%
525	Abdomen, Acute	2.3%
526	Fascioliasis	2.3%
527	Echinococcosis, Hepatic	2.2%
528	Chemical and Drug Induced Liver Injury, Chronic	2.2%
529	Reye Syndrome	2.2%
530	insulinoma	2.2%
531	Gastrinoma	2.2%
532	Glucagonoma	2.2%
533	Philadelphia Chromosome	2.2%
534	Respiratory Tract Fistula	2.1%
535	Massive Hepatic Necrosis	2.1%
536	Emphysematous Cholecystitis	2.1%
537	Sphincter of Oddi Dysfunction	2.1%
538	Body Weight	2.1%
539	Endotoxemia	2.1%
540	Apnea	2%
541	Cheyne-Stokes Respiration	2%
542	Decerebrate State	2%
543	Dyspnea	2%
544	Cardiomegaly	2%
545	Hemiparesis	2%
546	Hyperventilation	2%
547	Meningism	2%
548	Mouth Breathing	2%
549	Paresis	2%
550	Parovarian Cyst	2%
551	Pruritus	2%
552	Seizures	2%
553	Sensation Disorders	2%
554	Sneezing	2%
555	Spermatocele	2%
556	Erythema	2%
557	Oral Fistula	2%
558	Complex partial seizures	2%
559	Necrolytic Migratory Erythema	2%
560	Tachypnea	2%
561	Monoparesis	2%
562	Cutaneous Fistula	2%
563	Gait Disorders, Neurologic	2%
564	Neuromuscular Manifestations	2%
565	Cardiac Hypertrophy	2%
566	Autoimmune hepatitis	2%
567	Edema, Cardiac	2%
568	Mental Fatigue	2%
569	Hirsutism	2%
570	Orthostatic intolerance	2%
571	Hypoventilation	2%
572	Vaginal Fistula	2%
573	Body Weight Changes	2%
574	Vipoma	1.9%
575	Sarcopenia	1.9%
576	Nesidioblastosis	1.9%
577	Variegate Porphyria	1.9%
578	Acute intermittent porphyria	1.9%
579	Porphyria Cutanea Tarda	1.9%
580	Hoarseness	1.9%
581	Sleep Wake Disorders	1.8%
582	Pupil Disorders	1.8%
583	Neurobehavioral Manifestations	1.8%
584	Hepatitis, Viral, Animal	1.7%
585	Nasal Polyps	1.7%
586	Hepatitis E	1.7%
587	Pleural Rub	1.7%
588	Rales	1.7%
589	Respiratory Sounds	1.7%
590	Rhonchi	1.7%
591	Stridor	1.7%
592	Wheezing	1.7%
593	Asterixis	1.7%
594	Ballismus	1.7%
595	Hepatitis B	1.7%
596	Hepatitis C	1.7%
597	Vertigo	1.7%
598	Hepatitis A	1.7%
599	Pain	1.7%
600	Livedo Reticularis	1.7%
601	Ache	1.7%
602	Back Pain	1.7%
603	Bulimia	1.7%
604	Neck Pain	1.7%
605	Chest Pain	1.7%
606	Colonic Polyps	1.7%
607	Dizziness	1.7%
608	Dysuria	1.7%
609	Facial Pain	1.7%
610	Fever of Unknown Origin	1.7%
611	Flank Pain	1.7%
612	Headache	1.7%
613	Meningocele	1.7%
614	Nocturia	1.7%
615	Oliguria	1.7%
616	Pain, Intractable	1.7%
617	Pelvic Pain	1.7%
618	Polyuria	1.7%
619	Proteinuria	1.7%
620	Snoring	1.7%
621	Urinary Calculi	1.7%
622	Chronic pain	1.7%
623	Lightheadedness	1.7%
624	Pain, Referred	1.7%
625	Prostatism	1.7%
626	Throbbing Headache	1.7%
627	Labor Pain	1.7%
628	Cancer Pain	1.7%
629	Nociceptive Pain	1.7%
630	Encephalocele	1.7%
631	Hepatic Encephalopathy	1.7%
632	Gait Ataxia	1.6%
633	Underweight	1.6%
634	Overweight	1.6%
635	Candidemia	1.5%
636	Zellweger Syndrome	1.5%
637	Voice Disorders	1.5%
638	Voice Disturbance	1.5%
639	Gagging	1.4%
640	Akathisia	1.4%
641	Restlessness	1.4%
642	Psychomotor Agitation	1.4%
643	Leukoplakia, Oral	1.4%
644	Vesicovaginal Fistula	1.4%
645	Hepatolenticular Degeneration	1.4%
646	Congenital diaphragmatic hernia	1.4%
647	Morning Sickness	1.4%
648	Anosmia	1.3%
649	Ataxia	1.3%
650	Athetosis	1.3%
651	Catalepsy	1.3%
652	Dental Fistula	1.3%
653	Dystonia	1.3%
654	Hemiplegia	1.3%
655	Locked-In Syndrome	1.3%
656	Muscle Hypertonia	1.3%
657	Muscle hypotonia	1.3%
658	Myoclonus	1.3%
659	Myotonia	1.3%
660	Neuralgia	1.3%
661	Oroantral Fistula	1.3%
662	Paraplegia	1.3%
663	Pseudobulbar Palsy	1.3%
664	Quadriplegia	1.3%
665	Spasm	1.3%
666	Spastic Paraplegia	1.3%
667	Status Epilepticus	1.3%
668	Taste Disorders	1.3%
669	Tremor	1.3%
670	Monoplegia	1.3%
671	Hypokinesia	1.3%
672	Left Ventricular Hypertrophy	1.3%
673	Right Ventricular Hypertrophy	1.3%
674	Paraparesis	1.3%
675	Bradykinesia	1.3%
676	Waxy flexibility	1.3%
677	Action Tremor	1.3%
678	Resting Tremor	1.3%
679	Dysosmia	1.3%
680	Quadriparesis	1.3%
681	Olfaction Disorders	1.3%
682	Myokymia	1.3%
683	Somatosensory Disorders	1.3%
684	Neuropathic pain	1.3%
685	Hyperkinesia	1.3%
686	Intention tremor	1.3%
687	Gait Apraxia	1.3%
688	Uterine Prolapse	1.3%
689	Vaginal Prolapse	1.3%
690	Weight Gain	1.3%
691	Jet Lag Syndrome	1.3%
692	Reflex, Abnormal	1.3%
693	Hyporeflexia	1.3%
694	Hyperreflexia	1.3%
695	Emaciation	1.2%
696	Low Back Pain	1.2%
697	Visceral Pain	1.2%
698	Birth Weight	1.2%
699	Vision Disorders	1.1%
700	Metamorphopsia	1.1%
701	Visual Impairment	1.1%
702	Bronchial Fistula	1.1%
703	Metatarsalgia	1.1%
704	Anisocoria	1.1%
705	Confusion	1.1%
706	Facial paralysis	1.1%
707	Lethargy	1.1%
708	Memory Disorders	1.1%
709	Muscle Cramp	1.1%
710	Perceptual Disorders	1.1%
711	Psychomotor Disorders	1.1%
712	Tonic Pupil	1.1%
713	Anhedonia	1.1%
714	Disorientation	1.1%
715	Gastroschisis	1.1%
716	Fetal Hypoxia	1.1%
717	Facial Paresis	1.1%
718	Memory Loss	1.1%
719	Hemisensory Neglect	1.1%
720	Dysacusis	1.1%
721	Dyspnea, Paroxysmal	1.1%
722	Mastodynia	1.1%
723	Respiratory Paralysis	1.1%
724	Salivary Gland Fistula	1.1%
725	Chorea	1.1%
726	Cystocele	1.1%
727	Tetany	1.1%
728	Urinary Incontinence	1.1%
729	Breakthrough Pain	1.1%
730	Albuminuria	1.1%
731	Hemoglobinuria	1.1%
732	Alice in Wonderland Syndrome	1.1%
733	Cachexia	1%
734	Alexia	1%
735	Dyslexia	1%
736	Umbilical hernia	1%
737	Toothache	1%
738	Hydrops Fetalis	1%
739	Hyperemesis Gravidarum	1%
740	Dysgeusia	1%
741	Formication	1%
742	Hyperalgesia	1%
743	Hyperesthesia	1%
744	Hypesthesia	1%
745	Language Disorders	1%
746	Numbness	1%
747	Paresthesia	1%
748	Paraparesis, Spastic	1%
749	Trismus	1%
750	Epilepsia Partialis Continua	1%
751	Hypogeusia	1%
752	Brown-Sequard Syndrome	1%
753	Lockjaw	1%
754	Allodynia	1%
755	Ageusia	1%
756	Fetal Weight	1%
757	Consciousness Disorders	1%
758	Mental Retardation	1%
759	Depressed Level of Consciousness	1%
760	Mental deficiency	1%
761	Intellectual Disability	1%
762	Catatonia	1%
763	Musculoskeletal Pain	1%
764	Ophthalmoplegia	1%
765	External Ophthalmoplegia	1%
766	Aphonia	1%
767	Arthralgia	1%
768	Sleep Deprivation	1%
769	Polyarthralgia	1%
770	Dysphonia	1%
771	Cerebrospinal Fluid Otorrhea	0.9%
772	Cerebrospinal Fluid Rhinorrhea	0.9%
773	Rift Valley Fever	0.9%
774	Obesity	0.9%
775	Vocal Cord Paralysis	0.8%
776	Diplopia	0.8%
777	Muscle Rigidity	0.8%
778	Muscle Spasticity	0.8%
779	Scotoma	0.8%
780	Photophobia	0.8%
781	Cogwheel Rigidity	0.8%
782	Hemifacial Spasm	0.8%
783	Amaurosis	0.8%
784	Blindness	0.8%
785	Nuchal Rigidity	0.8%
786	Angina Pectoris	0.8%
787	Agnosia	0.8%
788	Apraxias	0.8%
789	Urinary Bladder Fistula	0.8%
790	Hallucinations	0.8%
791	Hemianopsia	0.8%
792	Hyperacusis	0.8%
793	Tinnitus	0.8%
794	Visual Agnosia	0.8%
795	Anosognosia	0.8%
796	Wernicke-Korsakoff Syndrome	0.8%
797	Phonophobia	0.8%
798	Hearing Loss	0.8%
799	Cerebellar Ataxia	0.8%
800	Torticollis	0.8%
801	Agraphia	0.8%
802	Anomia	0.8%
803	Cluttering	0.8%
804	Language Development Disorders	0.8%
805	Speech Disorders	0.8%
806	Syncope	0.8%
807	Stupor	0.8%
808	Dysgraphia	0.8%
809	Presyncope	0.8%
810	Dyslalia	0.8%
811	Sciatica	0.8%
812	Urge Incontinence	0.8%
813	Tardive Dyskinesia	0.8%
814	Tinea Pedis	0.8%
815	Dyskinesia, Drug-Induced	0.7%
816	Aphasia	0.7%
817	Articulation Disorders	0.7%
818	Echolalia	0.7%
819	Stuttering	0.7%
820	Dysphasia	0.7%
821	Alcohol Withdrawal Seizures	0.7%
822	Arteriovenous fistula	0.7%
823	Amblyopia	0.7%
824	Amnesia	0.7%
825	Delirium	0.7%
826	Horner Syndrome	0.7%
827	Dissociative Amnesia	0.7%
828	Color blindness	0.7%
829	Global Amnesia	0.7%
830	Shoulder Pain	0.7%
831	Pediatric Obesity	0.7%
832	Dysarthria	0.7%
833	Amaurosis Fugax	0.7%
834	Blindness, Cortical	0.7%
835	Dyscalculia	0.7%
836	Angina, Unstable	0.7%
837	Deafness	0.7%
838	Hearing Loss, Sudden	0.7%
839	Gerstmann Syndrome	0.7%
840	Hearing Loss, Bilateral	0.7%
841	Hearing Loss, High-Frequency	0.7%
842	Hearing Loss, Mixed Conductive-Sensorineural	0.7%
843	Prosopagnosia	0.7%
844	Apraxia, Ideomotor	0.7%
845	Persistent Vegetative State	0.7%
846	Charles Bonnet Syndrome	0.7%
847	Hearing Loss, Unilateral	0.7%
848	Complete Hearing Loss	0.7%
849	Alien Hand Syndrome	0.7%
850	Deaf Mutism	0.7%
851	Kidney Calculi	0.7%
852	Ureteral Calculi	0.7%
853	Akathisia, Drug-Induced	0.6%
854	Myalgia	0.6%
855	Mutism	0.6%
856	Selective Mutism	0.6%
857	Angina Pectoris, Variant	0.6%
858	Retrograde amnesia	0.6%
859	Amnesia, Anterograde	0.6%
860	Alexia, Pure	0.6%
861	Auditory Perceptual Disorders	0.5%
862	Amnesia, Transient Global	0.5%
863	Ophthalmoplegic Migraine	0.5%
864	Progressive supranuclear palsy	0.5%
865	Kearns-Sayre syndrome	0.3%

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