MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Cholestasis, Extrahepatic

(UMLS:C0005398)

Definition:: Impairment of bile flow in the large BILE DUCTS by mechanical obstruction or stricture due to benign or malignant processes.
UMLS ID:: C0005398
MeSH ID:: D001651

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.130.120.135.150

Synonym(s)

Cholestasis, Extrahepatic

BILIARY OBSTRUCTION EXTRAHEPATIC

Extrahepatic Bile Duct Obstruction

Extrahepatic Biliary Stasis

Extrahepatic Cholestasis

Extrahepatic cholestasis

Extrahepatic obstructive biliary disease

cholestasis extrahepatic

extrahepatic biliary obstruction

10.

extrahepatic cholestasis

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Bilirubin	30026087	CTD
2	Diosmin	30026087	CTD
3	Glutathione	30026087	CTD
4	Malondialdehyde	28789951 30026087	CTD
5	Phenytoin	7283297	CTD
6	Sildenafil Citrate	30026087	CTD
7	Taurine	27501764	CTD
8	Zinc Acetate	27501764	CTD
9	rosmarinic acid	28789951	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Cholangitis	34.4%
2	Common Bile Duct Diseases	34.4%
3	Cholelithiasis	25.4%
4	Choledocholithiasis	25%
5	Biliary cirrhosis	23.3%
6	Biliary Dyskinesia	22.6%
7	Cholangitis, Sclerosing	22.6%
8	Bile Duct Neoplasms	21.7%
9	Cholecystolithiasis	19.8%
10	Choledochal Cyst	17.7%
11	Sphincter of Oddi Dysfunction	16.8%
12	Gastrointestinal Diseases	16.4%
13	Liver diseases	16.4%
14	Pancreatic Diseases	16.4%
15	Cholecystitis	14.8%
16	gallbladder neoplasm	13.8%
17	Digestive System Neoplasms	10.8%
18	Acalculous Cholecystitis	9.7%
19	Gastrointestinal Neoplasms	8.5%
20	Liver neoplasms	8.5%
21	Chylous Ascites	8.5%
22	Esophageal Diseases	8.5%
23	Fatty Liver	8.5%
24	Gastroenteritis	8.5%
25	Hepatitis	8.5%
26	Portal Hypertension	8.5%
27	Intestinal Diseases	8.5%
28	Liver Cirrhosis	8.5%
29	Pancreatic Fistula	8.5%
30	Pancreatic Insufficiency	8.5%
31	Pancreatitis	8.5%
32	Pneumoperitoneum	8.5%
33	Stomach Diseases	8.5%
34	Focal Nodular Hyperplasia	8.5%
35	Hepatic Insufficiency	8.5%
36	Steatohepatitis	8.5%
37	Emphysematous Cholecystitis	7.2%
38	Mesenteric vascular insufficiency	6.8%
39	Peritoneal Neoplasms	6.8%
40	Esophageal Atresia	6.7%
41	Intestinal Atresia	6.7%
42	Mesenteric Vascular Occlusion	6.7%
43	Intestinal Fistula	6.7%
44	Enterocutaneous Fistula	6.7%
45	Dysentery	6.6%
46	Enteritis	6.6%
47	Enterocolitis	6.6%
48	Esophageal and Gastric Varices	6.6%
49	Esophagitis	6.6%
50	Gastritis	6.6%
51	Inflammatory Bowel Diseases	6.6%
52	Zollinger-Ellison syndrome	6.4%
53	Liver Diseases, Parasitic	6%
54	Intestinal Neoplasms	5.9%
55	Stomach Neoplasms	5.9%
56	Hepatic Veno-Occlusive Disease	5.7%
57	Pancreatic Cyst	5.7%
58	Peliosis Hepatis	5.7%
59	Hepatopulmonary Syndrome	5.7%
60	Pancreatic Neoplasm	5.7%
61	Anus, Imperforate	5.6%
62	Gastrointestinal Hemorrhage	5.6%
63	Hemoperitoneum	5.6%
64	Hepatomegaly	5.6%
65	Mesenteric Panniculitis	5.6%
66	Panniculitis, Peritoneal	5.6%
67	Peritonitis	5.6%
68	Peritoneal Fibrosis	5.6%
69	Encapsulating Peritoneal Sclerosis	5.6%
70	Anorectal Malformations	5.6%
71	Biliary Fistula	5.6%
72	Gastric Fistula	5.6%
73	Hepatic Vein Thrombosis	5.5%
74	Liver Abscess	5.5%
75	Budd-Chiari Syndrome	5.5%
76	Tuberculosis, Gastrointestinal	5.5%
77	Colitis	5.4%
78	Duodenogastric Reflux	5.4%
79	Peptic Ulcer	5.4%
80	Proctitis	5.4%
81	Esophageal Neoplasms	4.9%
82	Cecal Diseases	4.9%
83	Colonic Diseases	4.9%
84	Esophageal Stenosis	4.9%
85	Hepatitis, Chronic	4.9%
86	Ileal Diseases	4.9%
87	Intestinal Obstruction	4.9%
88	Intestinal Perforation	4.9%
89	Jejunal Diseases	4.9%
90	Pneumatosis Cystoides Intestinalis	4.9%
91	Rectal Diseases	4.9%
92	Gastric Dilatation	4.9%
93	Liver Failure	4.9%
94	Pancreatitis, Chronic	4.9%
95	Gastric outlet obstruction	4.9%
96	Gastrointestinal Stromal Tumors	4.9%
97	Cronkhite-Canada Syndrome	4.9%
98	Non-alcoholic Fatty Liver Disease	4.9%
99	Chronic active hepatitis	4.9%
100	Intestinal Polyposis	4.9%
101	Fatty Liver, Alcoholic	4.9%
102	Hepatitis, Alcoholic	4.9%
103	Liver Cirrhosis, Alcoholic	4.9%
104	Duodenitis	4.8%
105	Ileitis	4.8%
106	Erosive Duodenitis	4.8%
107	Colorectal Neoplasms	4.6%
108	Proctocolitis	4.5%
109	Rectal Fistula	4.5%
110	Anal Fistula	4.5%
111	Chemical and Drug Induced Liver Injury	4.3%
112	Crohn Disease	4.3%
113	Duodenal Obstruction	4.3%
114	Enterocolitis, Neutropenic	4.3%
115	Necrotizing Enterocolitis	4.3%
116	Cecal Neoplasms	4.3%
117	Duodenal Neoplasms	4.3%
118	Hepatorenal Syndrome	4.2%
119	Appendicitis	4.1%
120	Hepatocellular Adenoma	3.9%
121	Duodenal Ulcer	3.7%
122	Peptic Ulcer Perforation	3.7%
123	Gastric ulcer	3.7%
124	Pouchitis	3.6%
125	Esophageal Perforation	3.5%
126	Hepatitis, Animal	3.5%
127	Hepatitis, Viral, Human	3.5%
128	Intestinal Diseases, Parasitic	3.5%
129	Cystic Fibrosis	3.5%
130	Barrett Esophagus	3.4%
131	Deglutition Disorders	3.4%
132	Porphyrias, Hepatic	3.4%
133	Congenital Hyperinsulinism	3.4%
134	Liver Abscess, Amebic	3.3%
135	Liver Neoplasms, Experimental	3.3%
136	Achlorhydria	3.3%
137	Liver Cirrhosis, Experimental	3.3%
138	Pancreatic Pseudocyst	3.3%
139	Gastric Antral Vascular Ectasia	3.3%
140	Peptic Ulcer Hemorrhage	3.3%
141	Gastroparesis	3.3%
142	Pancreatitis, Alcoholic	3.3%
143	Colonic Diseases, Functional	3.2%
144	Enterocolitis, Pseudomembranous	3.2%
145	Esophageal motility disorders	3.2%
146	Fecal Incontinence	3.2%
147	Fecal Impaction	3.2%
148	Intussusception	3.2%
149	Mallory-Weiss Syndrome	3.2%
150	Megacolon	3.2%
151	Pyloric Stenosis	3.2%
152	Liver Failure, Acute	3.2%
153	End Stage Liver Disease	3.2%
154	pseudomembranous colitis	3.2%
155	Ileus	3.2%
156	Dysentery, Bacillary	3.2%
157	Meconium ileus	3.2%
158	Appendiceal Neoplasms	3.2%
159	Colonic Neoplasms	3.2%
160	Rectal Neoplasms	3.2%
161	Anus Neoplasms	2.9%
162	Sigmoid Neoplasms	2.9%
163	Colonic Pseudo-Obstruction	2.9%
164	Colitis, Ischemic	2.9%
165	Adenomatous Polyposis Coli	2.6%
166	Fascioliasis	2.5%
167	Echinococcosis, Hepatic	2.5%
168	Melena	2.5%
169	Chemical and Drug Induced Liver Injury, Chronic	2.5%
170	Reye Syndrome	2.5%
171	Hematemesis	2.4%
172	Carcinoma, Pancreatic Ductal	2.4%
173	Massive Hepatic Necrosis	2.4%
174	Esophageal Achalasia	2.4%
175	Anal Fissure	2.4%
176	Intestinal Pseudo-Obstruction	2.4%
177	Irritable Bowel Syndrome	2.4%
178	Superior Mesenteric Artery Syndrome	2.4%
179	Neurogenic Bowel	2.4%
180	Anal Ulcer	2.4%
181	Hepatitis B, Chronic	2.3%
182	Hepatitis C, Chronic	2.3%
183	Hemorrhoids	2.2%
184	Autoimmune hepatitis	2.2%
185	Afferent Loop Syndrome	2.2%
186	Celiac Disease	2.2%
187	Short Bowel Syndrome	2.2%
188	Sprue, Tropical	2.2%
189	Steatorrhea	2.2%
190	Rectocele	2.2%
191	Sprue	2.2%
192	Diverticulitis	2.2%
193	Dumping Syndrome	2.2%
194	Rectal Prolapse	2.2%
195	Nesidioblastosis	1.9%
196	Variegate Porphyria	1.9%
197	Acute intermittent porphyria	1.9%
198	Porphyria Cutanea Tarda	1.9%
199	insulinoma	1.8%
200	Gastrinoma	1.8%
201	Glucagonoma	1.8%
202	Hepatitis, Viral, Animal	1.8%
203	Giardiasis	1.7%
204	Hepatitis E	1.7%
205	Hepatitis B	1.7%
206	Hepatitis C	1.7%
207	Diverticulum	1.7%
208	Hepatitis A	1.7%
209	Diverticulosis	1.7%
210	Hepatic Encephalopathy	1.6%
211	Pruritus Ani	1.6%
212	Vipoma	1.6%
213	Zellweger Syndrome	1.5%
214	Laryngopharyngeal Reflux	1.4%
215	Hepatolenticular Degeneration	1.4%
216	Peutz-Jeghers Syndrome	1.3%
217	Lactose Intolerance	1.3%
218	Cryptosporidiosis	1%
219	Rift Valley Fever	0.7%
220	CREST Syndrome	0.7%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120237