MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Vitamin A Deficiency

(UMLS:C0042842)

Definition:: A nutritional condition produced by a deficiency of VITAMIN A in the diet, characterized by NIGHT BLINDNESS and other ocular manifestations such as dryness of the conjunctiva and later of the cornea (XEROPHTHALMIA). Vitamin A deficiency is a very common problem worldwide, particularly in developing countries as a consequence of famine or shortages of vitamin A-rich foods. In the United States it is found among the urban poor, the elderly, alcoholics, and patients with malabsorption. (From Cecil Textbook of Medicine, 19th ed, p1179)
UMLS ID:: C0042842
MeSH ID:: D014802

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.654.521.500.133.628

Synonym(s)

Vitamin A Deficiency

Deficiency of vitamin A

Hypovitaminosis A

Hypovitaminosis A, NOS

Low levels of vitamin A

Unspecified vitamin A deficiency

VITAMIN A DEFICIENCY

Vitamin A deficiency

Vitamin A deficiency disease

10.

Vitamin A deficiency, NOS

11.

Vitamin A deficiency, unspecified

12.

deficiencies disease vitamins

13.

deficiencies vitamin

14.

deficiencies vitamins

15.

deficiency diseases vitamin

16.

deficiency of vitamin a

17.

deficiency vitamin a

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Everolimus	FAERS: 2		US FAERS
2	Isotretinoin	FAERS: 1		US FAERS
3	Octreotide	FAERS: 1		OFFSIDES US FAERS
4	Valsartan	FAERS: 1		OFFSIDES US FAERS
5	Zoledronic Acid	FAERS: 1		OFFSIDES US FAERS
6	lanreotide	FAERS: 1		US FAERS
7	Acebutolol			OFFSIDES
8	Acetazolamide			OFFSIDES
9	Atomoxetine Hydrochloride			OFFSIDES
10	Atorvastatin			OFFSIDES
11	Betaxolol			OFFSIDES
12	Bimatoprost			OFFSIDES
13	Biotin			OFFSIDES
14	Bortezomib			OFFSIDES
15	Calcitriol			OFFSIDES
16	Calcium Compounds			OFFSIDES
17	Carbamazepine			OFFSIDES
18	Cefixime			OFFSIDES
19	Chlorhexidine			OFFSIDES
20	Chloroquine			OFFSIDES
21	Desvenlafaxine Succinate			OFFSIDES
22	Diphenoxylate			OFFSIDES
23	Eplerenone			OFFSIDES
24	Estradiol			OFFSIDES
25	Famciclovir			OFFSIDES
26	Flurazepam			OFFSIDES
27	Fluvastatin			OFFSIDES
28	Fulvestrant			OFFSIDES
29	Gabapentin			OFFSIDES
30	Glipizide			OFFSIDES
31	Hydralazine			OFFSIDES
32	Hydron;carbonate			OFFSIDES
33	Hydroxyzine			OFFSIDES
34	Indinavir			OFFSIDES
35	Lenalidomide			OFFSIDES
36	Leuprolide			OFFSIDES
37	Linezolid			OFFSIDES
38	Linsidomine			OFFSIDES
39	Medigoxin			OFFSIDES
40	Molsidomine			OFFSIDES
41	Nabumetone			OFFSIDES
42	Nefopam			OFFSIDES
43	Norethindrone			OFFSIDES
44	Nortriptyline			OFFSIDES
45	NuvaRing			OFFSIDES
46	Olopatadine Hydrochloride			OFFSIDES
47	Oxazepam			OFFSIDES
48	Pamidronate			OFFSIDES
49	Pantoprazole			OFFSIDES
50	Phosphates			OFFSIDES
51	Pindolol			OFFSIDES
52	Primidone			OFFSIDES
53	Quinidine			OFFSIDES
54	Raloxifene Hydrochloride			OFFSIDES
55	Ranitidine			OFFSIDES
56	Ribavirin			OFFSIDES
57	Rilmenidine			OFFSIDES
58	Rosuvastatin Calcium			OFFSIDES
59	Saquinavir			OFFSIDES
60	Sertraline			OFFSIDES
61	Tamsulosin			OFFSIDES
62	Tenofovir			OFFSIDES
63	Tenofovir			OFFSIDES
64	Terbinafine			OFFSIDES
65	Thyroxine			OFFSIDES
66	Tretinoin			OFFSIDES
67	Ubiquinone			OFFSIDES
68	Vitamin A		16146918 16175781 16960172	CTD OFFSIDES
69	Vitamin D			OFFSIDES
70	adefovir dipivoxil			OFFSIDES
71	efavirenz			OFFSIDES
72	ferrous gluconate			OFFSIDES
73	fexofenadine			OFFSIDES
74	magnesium citrate			OFFSIDES
75	nefazodone			OFFSIDES
76	norgestimate, ethinyl estradiol drug combination			OFFSIDES
77	pipamperone			OFFSIDES
78	rizatriptan			OFFSIDES
79	rizatriptan			OFFSIDES
80	tegaserod			OFFSIDES
81	tegaserod			OFFSIDES
82	tizanidine			OFFSIDES
83	trospium chloride			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Ascorbic Acid Deficiency	49.2%
2	Vitamin D Deficiency	49.2%
3	Vitamin E Deficiency	49.2%
4	Folic Acid Deficiency	36.8%
5	Pellagra	36.8%
6	Thiamine Deficiency	36.8%
7	Vitamin B 12 Deficiency	36.8%
8	Vitamin B 6 Deficiency	36.8%
9	Pyridoxine Deficiency	36.8%
10	Magnesium Deficiency	36%
11	Potassium Deficiency	36%
12	Protein Deficiency	36%
13	Beriberi	30.6%
14	Starvation	28.5%
15	Refeeding Syndrome	28.5%
16	Vitamin K Deficiency	25.2%
17	Marasmus	23.8%
18	Child Nutrition Disorders	22.7%
19	Hypervitaminosis A	22.7%
20	Infant Nutrition Disorders	22.7%
21	Wasting Syndrome	20.6%
22	Anemia, Pernicious	20.4%
23	Scurvy	18.7%
24	Rickets	18.4%
25	Hyperhomocysteinemia	17.6%
26	Kwashiorkor	16.8%
27	Metabolic Diseases	15.3%
28	Osteomalacia	14.3%
29	Wernicke Encephalopathy	11.9%
30	Subacute Combined Degeneration	10.8%
31	Renal Osteodystrophy	9%
32	Renal rickets	9%
33	Acid-Base Imbalance	7.6%
34	Calcium Metabolism Disorders	7.6%
35	Iron Metabolism Disorders	7.6%
36	Phosphorus Metabolism Disorders	7.6%
37	Water-Electrolyte Imbalance	7.6%
38	Lipid Metabolism Disorders	7.6%
39	Mitochondrial Diseases	7.6%
40	Glucose Metabolism Disorders	7.6%
41	Familial Hypophosphatemic Rickets	5.7%
42	Hypercalcemia	5.5%
43	Hypocalcemia	5.5%
44	Milk-Alkali Syndrome	5.5%
45	HIV Wasting Syndrome	5.4%
46	Osteopenia	5.1%
47	Brain Diseases, Metabolic	5%
48	Obesity	4.8%
49	Lipodystrophy	4.1%
50	Acidosis	4.1%
51	Alkalosis	4.1%
52	Amyloidosis	4.1%
53	Calcinosis	4.1%
54	Hyperglycemia	4.1%
55	Hyperinsulinism	4.1%
56	Hyperkalemia	4.1%
57	Hypernatremia	4.1%
58	Hypoglycemia	4.1%
59	Hypokalemia	4.1%
60	Hyponatremia	4.1%
61	Xanthomatosis	4.1%
62	Hypophosphatemia	4.1%
63	Metabolic acidosis	4.1%
64	Dyslipidemias	4.1%
65	Iron Overload	4.1%
66	Xanthoma	4.1%
67	Obesity, Abdominal	3.6%
68	Pseudohypoparathyroidism	3.5%
69	Brain Diseases, Metabolic, Inborn	3.3%
70	Diabetes Mellitus	2.9%
71	Pediatric Obesity	2.9%
72	Dehydration	2.8%
73	Lipomatosis	2.8%
74	Water Intoxication	2.8%
75	Werner Syndrome	2.8%
76	Achlorhydria	2.7%
77	Amino Acid Metabolism, Inborn Errors	2.7%
78	Bloom Syndrome	2.7%
79	Carbohydrate Metabolism, Inborn Errors	2.7%
80	Metal Metabolism, Inborn Errors	2.7%
81	Osteoporosis	2.7%
82	Progeria	2.7%
83	Lysosomal Storage Diseases	2.7%
84	Bone Demineralization, Pathologic	2.7%
85	Cytochrome-c Oxidase Deficiency	2.7%
86	Peroxisomal Disorders	2.7%
87	Post-Traumatic Osteoporosis	2.7%
88	Celiac Disease	2.7%
89	Sprue, Tropical	2.7%
90	Steatorrhea	2.7%
91	Sprue	2.7%
92	Leigh Disease	2.6%
93	Lactose Intolerance	2.6%
94	Prader-Willi Syndrome	2.5%
95	Hypolipoproteinemias	2.4%
96	Acidosis, Lactic	2.4%
97	Calciphylaxis	2.4%
98	Hemosiderosis	2.4%
99	Ketosis	2.4%
100	Ketonuria	2.4%
101	Ketoacidosis	2.4%
102	Ketonemia	2.4%
103	Vascular calcification	2.4%
104	Carbamoyl-Phosphate Synthase I Deficiency Disease	2.2%
105	Mitochondrial Encephalomyopathies	2.2%
106	Mitochondrial Myopathies	2.1%
107	Smith-Lemli-Opitz Syndrome	2.1%
108	Myelinolysis, Central Pontine	2.1%
109	Galactosemias	2.1%
110	Urea Cycle Disorders, Inborn	2.1%
111	Tyrosinemias	2.1%
112	Glycosuria	2%
113	Reye Syndrome	2%
114	Hepatic Encephalopathy	2%
115	Diabetic Ketoacidosis	2%
116	Congenital Hyperinsulinism	2%
117	Hyperlipidemia, Familial Combined	2%
118	Hyperlipoproteinemia Type IV	1.9%
119	Hyperlipoproteinemia Type V	1.9%
120	Hyperphosphaturia	1.8%
121	Hyperlipoproteinemia Type III	1.8%
122	Porphyrias, Hepatic	1.7%
123	Necrobiosis Lipoidica Diabeticorum	1.6%
124	Acidosis, Respiratory	1.6%
125	Adiposis Dolorosa	1.6%
126	Alkalosis, Respiratory	1.6%
127	Homocystinuria	1.6%
128	Fanconi Anemia	1.6%
129	Renal tubular acidosis	1.6%
130	Alkaptonuria	1.6%
131	Glycogen Storage Disease	1.6%
132	Hypophosphatasia	1.6%
133	Insulin Resistance	1.6%
134	Osteoporosis, Postmenopausal	1.6%
135	Propionic acidemia	1.6%
136	Dihydropyrimidine Dehydrogenase Deficiency	1.6%
137	Cystinosis	1.6%
138	Hypercholesterolemia	1.6%
139	Hyperlipoproteinemias	1.6%
140	Hypertriglyceridemia	1.6%
141	Hypoalphalipoproteinemias	1.6%
142	Amyloid Neuropathies, Familial	1.4%
143	Glycogen storage disease type II	1.4%
144	HIV-Associated Lipodystrophy Syndrome	1.4%
145	Neuronal Ceroid-Lipofuscinoses	1.3%
146	Friedreich Ataxia	1.3%
147	Zellweger Syndrome	1.3%
148	Menkes Kinky Hair Syndrome	1.3%
149	Nesidioblastosis	1.3%
150	MELAS Syndrome	1.3%
151	Gestational Diabetes	1.3%
152	Latent Autoimmune Diabetes in Adults	1.3%
153	Gaucher Disease	1.3%
154	Diabetes Mellitus, Experimental	1.2%
155	Adrenoleukodystrophy	1.2%
156	Hepatolenticular Degeneration	1.2%
157	Nephrocalcinosis	1.2%
158	Tetany	1.2%
159	Refsum Disease	1.2%
160	Glycosuria, Renal	1.2%
161	Cerebral Amyloid Angiopathy	1.2%
162	Kernicterus	1.2%
163	Cockayne Syndrome	1.2%
164	Mucopolysaccharidosis III	1.1%
165	Glycogen Storage Disease Type I	1.1%
166	Glycogen Storage Disease Type V	1.1%
167	Ataxia Telangiectasia	1%
168	Kearns-Sayre syndrome	1%
169	Optic Atrophy, Hereditary, Leber	1%
170	Familial Periodic Paralysis	1%
171	Primary amyloidosis	1%
172	Fabry Disease	1%
173	Variegate Porphyria	1%
174	Acute intermittent porphyria	1%
175	Porphyria Cutanea Tarda	1%
176	Renal Aminoacidurias	1%
177	Fanconi Syndrome	1%
178	Pseudohypoaldosteronism	1%
179	Liddle Syndrome	1%
180	Niemann-Pick Disease, Type C	0.9%
181	Xeroderma Pigmentosum	0.9%
182	Tay-Sachs Disease	0.9%
183	Gout	0.8%
184	Amyotrophic Lateral Sclerosis	0.8%
185	Sjogren-Larsson Syndrome	0.8%
186	Antley-Bixler Syndrome Phenotype	0.8%
187	Canavan Disease	0.7%
188	Alexander Disease	0.7%
189	Mucopolysaccharidosis II	0.7%
190	CREST Syndrome	0.7%
191	Hypokalemic periodic paralysis	0.6%
192	Frontotemporal dementia	0.6%
193	Cystinuria	0.6%
194	Albinism	0.6%
195	Arthritis, Gouty	0.5%
196	Ichthyosis, X-Linked	0.5%

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