MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hepatitis C, Chronic

(UMLS:C0524910)

Definition:: INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS.
UMLS ID:: C0524910
MeSH ID:: D019698

Classification 1:

Name:

Virus Diseases
MeSH Tree Number(s):: C02.440.440.120|C02.782.350.350.120

Classification 2:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.552.380.350.120|C06.552.380.705.440.120

Synonym(s)

Hepatitis C, Chronic

Chronic hepatitis C

Chronic type C viral hepatitis

Chronic viral hepatitis C

c chronic hepatitis

chronic hepatitis C

chronic hepatitis c

chronic hepatitis, C virus

hepatitis c chronic

10.

hepatitis; virus, chronic, type C

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Azathioprine	9278222	CTD
2	BMS-790052	25987834	CTD
3	Bezafibrate	12586603 16792537 16933007	CTD
4	Buprenorphine	19383935	CTD
5	Indomethacin	15135802	CTD
6	Prednisolone	10213131	CTD
7	Ribavirin	View details 1505907 8752565 8914004 9011471 9278222 9860407 9875657 10733558 11330434 11451176 11454181 11705128 11807019 12080234 12197841 12197842 12540795 12642748 12713065 12736713 12853993 14558405 14586905 14738562 14768501 14992966 15117320 15131791 15219067 15220675 15293138 15316444 15468613 15482540 15580403 15597026 15622486 15660393 15667486 15751770 15754628 15778976 15828854 15951019 15996025 16023976 16124712 16169782 16340643 16462543 16476009 16597599 16629641 16633111 16637862 16679707 16702862 16710591 16785129 16872308 16937480 16980747 17001400 17032408 17048050 17058596 17107736 17118125 17168855 17204208 17249181 17287904 17311621 17406822 17409018 17470380 17501757 17511042 17548949 17559739 17589934 17591516 17714473 17879419 17898559 17913610 17934275 17987400 18097301 18187830 18200424 18223489 18294165 18606596 18702333 18756437 18778198 18855993 19091439 19337648 19404206 19527724 19565068 19565241 19749757 19749758 19783887 19789525 19897271 19950239 20009130 20362408 20377423 20446436 20547162 20698227 20710050 21307632 24927617	CTD
8	Simeprevir	25987834 26239358	CTD
9	Sofosbuvir	25987834 26239358	CTD
10	Ursodeoxycholic Acid	9058296 19073151	CTD
11	Vitamin A	11012474	CTD
12	ledipasvir	25987834	CTD
13	ribavirin amidine	17470380 19040344 20721883	CTD
14	telaprevir	24927617	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hepatitis E	38.2%
2	Hepatitis B, Chronic	34.8%
3	Hepatitis A	32.1%
4	Hepatitis B	31.3%
5	Hepatitis, Alcoholic	25.6%
6	Autoimmune hepatitis	22.2%
7	Rift Valley Fever	21.8%
8	Hepatitis, Animal	21.7%
9	Hepatitis, Viral, Animal	21.1%
10	Dengue Fever	19.3%
11	Yellow Fever	19.3%
12	Fatty Liver	18.8%
13	Portal Hypertension	18.8%
14	Liver Cirrhosis	18.8%
15	Focal Nodular Hyperplasia	18.8%
16	Hepatic Insufficiency	18.8%
17	Steatohepatitis	18.8%
18	Liver neoplasms	18.1%
19	Hepatitis, Viral, Human	16.9%
20	Biliary cirrhosis	16.5%
21	Flavivirus Infections	16.3%
22	Liver Diseases, Parasitic	16.2%
23	Hepatic Veno-Occlusive Disease	15.9%
24	Peliosis Hepatis	15.9%
25	Hepatopulmonary Syndrome	15.9%
26	Hepatomegaly	15.7%
27	Hepatic Vein Thrombosis	15.6%
28	Liver Abscess	15.6%
29	Budd-Chiari Syndrome	15.6%
30	Hemorrhagic Fever, Crimean	15.5%
31	Fatty Liver, Alcoholic	15.3%
32	Liver Cirrhosis, Alcoholic	15.3%
33	Zika Virus Infection	15.3%
34	Hemorrhagic Fever, American	14.2%
35	Lassa Fever	14.2%
36	Orthomyxoviridae Infections	13.9%
37	Picornaviridae Infections	13.9%
38	Reoviridae Infections	13.9%
39	Retroviridae Infections	13.9%
40	Chemical and Drug Induced Liver Injury	13.7%
41	Hepatorenal Syndrome	13.4%
42	Phlebotomus Fever	13.2%
43	West Nile Fever	13.2%
44	Arbovirus Infections	12.9%
45	Liver Abscess, Amebic	12.1%
46	Warts	12.1%
47	Esophageal and Gastric Varices	12%
48	Hemorrhagic Fever with Renal Syndrome	11.9%
49	Biliary Tract Diseases	11.9%
50	Gastrointestinal Diseases	11.9%
51	Pancreatic Diseases	11.9%
52	Porphyrias, Hepatic	11.8%
53	Murine Acquired Immunodeficiency Syndrome	11.5%
54	Hepatitis, Chronic	11.4%
55	Chronic active hepatitis	11.4%
56	Hepatitis C, Chronic	10.9%
57	Hepatitis C	10.8%
58	Liver Failure	10.7%
59	Non-alcoholic Fatty Liver Disease	10.7%
60	Viremia	10.6%
61	Subacute Sclerosing Panencephalitis	10.4%
62	Digestive System Neoplasms	10%
63	Epstein-Barr Virus Infections	9.9%
64	Opportunistic Infections	9.5%
65	Acquired Immunodeficiency Syndrome	9.4%
66	AIDS related complex	9.4%
67	Condylomata Acuminata	9.4%
68	Simian Acquired Immunodeficiency Syndrome	9.4%
69	Pneumonia, Viral	9.2%
70	Leukoencephalopathy, Progressive Multifocal	9.2%
71	Gastrointestinal Neoplasms	9.1%
72	Pancreatic Fistula	9%
73	Liver Cirrhosis, Experimental	9%
74	Hepatocellular Adenoma	9%
75	Molluscum Contagiosum	8.5%
76	Enterovirus Infections	8.5%
77	Paramyxoviridae Infections	8.5%
78	Cardiovirus Infections	8.5%
79	Rhabdoviridae Infections	8.5%
80	Zollinger-Ellison syndrome	8.3%
81	Chronic Fatigue Syndrome	8.1%
82	Sexually Transmitted Diseases	8.1%
83	Liver Neoplasms, Experimental	8%
84	Peritoneal Neoplasms	7.9%
85	Fascioliasis	7.8%
86	Echinococcosis, Hepatic	7.8%
87	Chemical and Drug Induced Liver Injury, Chronic	7.7%
88	Epidermodysplasia Verruciformis	7.7%
89	Reye Syndrome	7.7%
90	Pseudorabies	7.6%
91	HIV Infections	7.5%
92	Herpangina	7.5%
93	Erythema Infectiosum	7.4%
94	Foot-and-Mouth Disease	7.3%
95	Herpesviridae Infections	7.3%
96	Polyomavirus Infections	7.3%
97	Common Cold	7.2%
98	Influenza	7.2%
99	Catarrh	7.2%
100	Mesenteric vascular insufficiency	7.2%
101	Pancreatic Neoplasm	7.1%
102	Esophageal Atresia	7.1%
103	Intestinal Atresia	7.1%
104	Mesenteric Vascular Occlusion	7.1%
105	Intestinal Fistula	7.1%
106	Enterocutaneous Fistula	7.1%
107	Herpes Zoster Ophthalmicus	7%
108	Liver Failure, Acute	6.8%
109	End Stage Liver Disease	6.8%
110	Bile Duct Neoplasms	6.7%
111	gallbladder neoplasm	6.7%
112	Intestinal Neoplasms	6.7%
113	Stomach Neoplasms	6.7%
114	Variegate Porphyria	6.7%
115	Acute intermittent porphyria	6.7%
116	Porphyria Cutanea Tarda	6.7%
117	Zellweger Syndrome	6.6%
118	AIDS-Related Opportunistic Infections	6.6%
119	Keratitis, Herpetic	6.6%
120	Cytomegalovirus Retinitis	6.6%
121	Exanthema Subitum	6.6%
122	Bile Duct Diseases	6.3%
123	Cholelithiasis	6.3%
124	Chylous Ascites	6.3%
125	Esophageal Diseases	6.3%
126	Gastroenteritis	6.3%
127	Intestinal Diseases	6.3%
128	Pancreatic Insufficiency	6.3%
129	Pancreatitis	6.3%
130	Pneumoperitoneum	6.3%
131	Stomach Diseases	6.3%
132	Choledochal Cyst	6.3%
133	Hepatolenticular Degeneration	6.2%
134	Esophageal Neoplasms	6%
135	Dysentery	6%
136	Enteritis	6%
137	Enterocolitis	6%
138	Esophagitis	6%
139	Gastritis	6%
140	Inflammatory Bowel Diseases	6%
141	Cholecystolithiasis	6%
142	Coxsackievirus Infections	5.8%
143	Rubella	5.8%
144	Coronavirus Infections	5.8%
145	Nipah Virus Infection	5.8%
146	Hydrophobia	5.8%
147	Colorectal Neoplasms	5.6%
148	HIV Seropositivity	5.6%
149	Eczema Herpeticum	5.6%
150	Pancreatic Cyst	5.3%
151	Superinfection	5.3%
152	Anus, Imperforate	5.2%
153	Gastrointestinal Hemorrhage	5.2%
154	Hemoperitoneum	5.2%
155	Mesenteric Panniculitis	5.2%
156	Panniculitis, Peritoneal	5.2%
157	Peritonitis	5.2%
158	Peritoneal Fibrosis	5.2%
159	Encapsulating Peritoneal Sclerosis	5.2%
160	Anorectal Malformations	5.2%
161	Biliary Fistula	5.2%
162	Gastric Fistula	5.2%
163	Tuberculosis, Gastrointestinal	5.2%
164	Proctocolitis	5.2%
165	Gastrointestinal Stromal Tumors	5.1%
166	Rectal Fistula	5.1%
167	Anal Fistula	5.1%
168	Cecal Neoplasms	5%
169	Duodenal Neoplasms	5%
170	Genital Herpes	4.9%
171	Porcine Reproductive and Respiratory Syndrome	4.9%
172	Colitis	4.9%
173	Duodenogastric Reflux	4.9%
174	Herpes Labialis	4.9%
175	HTLV-I Infections	4.9%
176	Peptic Ulcer	4.9%
177	Proctitis	4.9%
178	Choledocholithiasis	4.9%
179	Hepatic Encephalopathy	4.9%
180	Duodenitis	4.8%
181	Ileitis	4.8%
182	Erosive Duodenitis	4.8%
183	Massive Hepatic Necrosis	4.8%
184	Cytomegalovirus Infections	4.6%
185	Smallpox	4.6%
186	Varicella Zoster Virus Infection	4.6%
187	Measles	4.5%
188	Pleurodynia, Epidemic	4.5%
189	Respiratory Syncytial Virus Infections	4.5%
190	HIV Wasting Syndrome	4.3%
191	AIDS Dementia Complex	4.3%
192	AIDS-Associated Nephropathy	4.3%
193	Vesicular Stomatitis	4.3%
194	Burkitt Lymphoma	4.3%
195	Appendicitis	4.2%
196	Cystic Fibrosis	4%
197	Congenital Hyperinsulinism	3.9%
198	HIV-Associated Lipodystrophy Syndrome	3.9%
199	Gastroenteritis, Transmissible, of Swine	3.8%
200	Severe Acute Respiratory Syndrome	3.8%
201	Crohn Disease	3.8%
202	Duodenal Obstruction	3.8%
203	Enterocolitis, Neutropenic	3.8%
204	Necrotizing Enterocolitis	3.8%
205	Mumps	3.8%
206	Poliomyelitis	3.7%
207	Cecal Diseases	3.6%
208	Cholangitis	3.6%
209	Cholecystitis	3.6%
210	Cholestasis	3.6%
211	Colonic Diseases	3.6%
212	Common Bile Duct Diseases	3.6%
213	Esophageal Stenosis	3.6%
214	Ileal Diseases	3.6%
215	Intestinal Obstruction	3.6%
216	Intestinal Perforation	3.6%
217	Jejunal Diseases	3.6%
218	Pneumatosis Cystoides Intestinalis	3.6%
219	Rectal Diseases	3.6%
220	Gastric Dilatation	3.6%
221	Pancreatitis, Chronic	3.6%
222	Gastric outlet obstruction	3.6%
223	Cronkhite-Canada Syndrome	3.6%
224	Intestinal Polyposis	3.6%
225	Appendiceal Neoplasms	3.6%
226	Colonic Neoplasms	3.6%
227	Rectal Neoplasms	3.6%
228	Pouchitis	3.4%
229	Adenomatous Polyposis Coli	3.4%
230	Anus Neoplasms	3.3%
231	Sigmoid Neoplasms	3.3%
232	Carcinoma, Pancreatic Ductal	3.2%
233	Chickenpox	3.2%
234	Enterocolitis, Pseudomembranous	3.2%
235	pseudomembranous colitis	3.2%
236	Dysentery, Bacillary	3.2%
237	Duodenal Ulcer	3.2%
238	Peptic Ulcer Perforation	3.2%
239	Gastric ulcer	3.2%
240	Esophageal Perforation	3.1%
241	Intestinal Diseases, Parasitic	3.1%
242	Barrett Esophagus	3%
243	Deglutition Disorders	3%
244	Achlorhydria	3%
245	Pancreatic Pseudocyst	3%
246	Gastric Antral Vascular Ectasia	3%
247	Peptic Ulcer Hemorrhage	3%
248	Gastroparesis	3%
249	Pancreatitis, Alcoholic	3%
250	Bell Palsy	2.9%
251	Colitis, Ischemic	2.8%
252	Melena	2.6%
253	Hematemesis	2.6%
254	Colonic Pseudo-Obstruction	2.4%
255	Cholestasis, Extrahepatic	2.3%
256	Biliary Dyskinesia	2.3%
257	Cholangitis, Sclerosing	2.3%
258	Colonic Diseases, Functional	2.3%
259	Esophageal motility disorders	2.3%
260	Fecal Incontinence	2.3%
261	Fecal Impaction	2.3%
262	Intussusception	2.3%
263	Mallory-Weiss Syndrome	2.3%
264	Megacolon	2.3%
265	Pyloric Stenosis	2.3%
266	Acalculous Cholecystitis	2.3%
267	Ileus	2.3%
268	Meconium ileus	2.3%
269	insulinoma	2.3%
270	Gastrinoma	2.2%
271	Glucagonoma	2.2%
272	Nesidioblastosis	2.2%
273	Infectious Mononucleosis	2%
274	Vipoma	2%
275	Hemorrhoids	1.9%
276	Afferent Loop Syndrome	1.9%
277	Celiac Disease	1.9%
278	Short Bowel Syndrome	1.9%
279	Sprue, Tropical	1.9%
280	Steatorrhea	1.9%
281	Rectocele	1.9%
282	Sprue	1.9%
283	Diverticulitis	1.9%
284	Dumping Syndrome	1.9%
285	Rectal Prolapse	1.9%
286	Giardiasis	1.7%
287	Herpes Zoster Oticus	1.6%
288	Diverticulum	1.6%
289	Diverticulosis	1.6%
290	Esophageal Achalasia	1.6%
291	Anal Fissure	1.6%
292	Intestinal Pseudo-Obstruction	1.6%
293	Irritable Bowel Syndrome	1.6%
294	Superior Mesenteric Artery Syndrome	1.6%
295	Emphysematous Cholecystitis	1.6%
296	Neurogenic Bowel	1.6%
297	Sphincter of Oddi Dysfunction	1.6%
298	Anal Ulcer	1.6%
299	Peutz-Jeghers Syndrome	1.4%
300	Lactose Intolerance	1.4%
301	Pruritus Ani	1.4%
302	Cryptosporidiosis	1.2%
303	Laryngopharyngeal Reflux	1.1%
304	CREST Syndrome	0.8%

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