MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Pouchitis

(UMLS:C0376620)

Definition:: Acute INFLAMMATION in the INTESTINAL MUCOSA of the continent ileal reservoir (or pouch) in patients who have undergone ILEOSTOMY and restorative proctocolectomy (PROCTOCOLECTOMY, RESTORATIVE).
UMLS ID:: C0376620
MeSH ID:: D019449

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405.205.462.624.500|C06.405.469.326.875.500|C06.405.469.420.520.500

Synonym(s)

Pouchitis

pouchitis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Isotretinoin	FAERS: 245	US FAERS
2	Prednisolone	FAERS: 19	US FAERS
3	rofecoxib	FAERS: 4	US FAERS
4	tofacitinib	FAERS: 2	US FAERS
5	Budesonide	FAERS: 1	OFFSIDES US FAERS
6	Ciprofloxacin	FAERS: 1	US FAERS
7	Clozapine	FAERS: 1	US FAERS
8	Fentanyl	FAERS: 1	US FAERS
9	Leuprolide	FAERS: 1	US FAERS
10	Metronidazole	FAERS: 1	US FAERS
11	Rivaroxaban	FAERS: 1	US FAERS
12	regorafenib	FAERS: 1	US FAERS
13	Amoxicillin		OFFSIDES
14	Atropine		OFFSIDES
15	Desoximetasone		OFFSIDES
16	Estradiol		OFFSIDES
17	Hydrocortisone		OFFSIDES
18	Imipramine		OFFSIDES
19	Mupirocin		OFFSIDES
20	Ranitidine		OFFSIDES
21	Ribavirin		OFFSIDES
22	Tretinoin		OFFSIDES
23	Valsartan	Canada Vigilance: 1	Canada Vigilance
24	calcipotriene		OFFSIDES
25	chlordiazepoxide, clidinium drug combination		OFFSIDES
26	montelukast		OFFSIDES
27	norgestimate, ethinyl estradiol drug combination		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Duodenitis	50.4%
2	Erosive Duodenitis	50.4%
3	Dysentery	48.5%
4	Enterocolitis	48.5%
5	Inflammatory Bowel Diseases	48.5%
6	Zollinger-Ellison syndrome	40.9%
7	Colitis	37.3%
8	Proctitis	37.3%
9	Proctocolitis	35.9%
10	Esophagitis	35.6%
11	Gastritis	35.6%
12	Cecal Diseases	34.1%
13	Colonic Diseases	34.1%
14	Intestinal Obstruction	34.1%
15	Intestinal Perforation	34.1%
16	Jejunal Diseases	34.1%
17	Pneumatosis Cystoides Intestinalis	34.1%
18	Rectal Diseases	34.1%
19	Cronkhite-Canada Syndrome	34.1%
20	Intestinal Polyposis	34.1%
21	Intestinal Neoplasms	33.6%
22	Colorectal Neoplasms	33.6%
23	Esophageal Diseases	33.1%
24	Stomach Diseases	33.1%
25	Duodenal Obstruction	32.6%
26	Appendicitis	31.3%
27	Mesenteric vascular insufficiency	31%
28	Duodenogastric Reflux	30.9%
29	Peptic Ulcer	30.9%
30	Intestinal Atresia	30.7%
31	Mesenteric Vascular Occlusion	30.7%
32	Intestinal Fistula	30.5%
33	Enterocutaneous Fistula	30.5%
34	Gastrointestinal Neoplasms	29.9%
35	Crohn Disease	28.8%
36	Enterocolitis, Neutropenic	28.8%
37	Necrotizing Enterocolitis	28.8%
38	Intestinal Diseases, Parasitic	28.6%
39	Cecal Neoplasms	27.6%
40	Duodenal Neoplasms	27.6%
41	Rectal Fistula	26.8%
42	Anal Fistula	26.8%
43	Gastrointestinal Hemorrhage	26.6%
44	Tuberculosis, Gastrointestinal	26.3%
45	Enteritis	25.9%
46	Stomach Neoplasms	24.4%
47	Enterocolitis, Pseudomembranous	24%
48	pseudomembranous colitis	24%
49	Dysentery, Bacillary	24%
50	Gastroenteritis	22%
51	Biliary Tract Diseases	21.5%
52	Liver diseases	21.5%
53	Pancreatic Diseases	21.5%
54	Esophageal Neoplasms	21.4%
55	Ileitis	20.8%
56	Colonic Diseases, Functional	20.3%
57	Fecal Incontinence	20.3%
58	Fecal Impaction	20.3%
59	Intussusception	20.3%
60	Megacolon	20.3%
61	Ileus	20.3%
62	Meconium ileus	20.3%
63	Ileal Diseases	20.1%
64	Colitis, Ischemic	19.7%
65	Esophageal Atresia	19.7%
66	Duodenal Ulcer	19.4%
67	Peptic Ulcer Perforation	19.4%
68	Gastric ulcer	19.4%
69	Esophageal and Gastric Varices	19.4%
70	Adenomatous Polyposis Coli	19.2%
71	Colonic Pseudo-Obstruction	18.9%
72	Appendiceal Neoplasms	18.2%
73	Colonic Neoplasms	18.2%
74	Rectal Neoplasms	18.2%
75	Anus Neoplasms	18.1%
76	Sigmoid Neoplasms	18.1%
77	Esophageal Stenosis	18.1%
78	Gastric Dilatation	18.1%
79	Gastric outlet obstruction	18.1%
80	Digestive System Neoplasms	17.4%
81	Hemorrhoids	16.6%
82	Afferent Loop Syndrome	16.4%
83	Celiac Disease	16.4%
84	Short Bowel Syndrome	16.4%
85	Sprue, Tropical	16.4%
86	Steatorrhea	16.4%
87	Rectocele	16.4%
88	Sprue	16.4%
89	Rectal Prolapse	16.3%
90	Gastrointestinal Stromal Tumors	16.2%
91	Esophageal Perforation	15.2%
92	Liver neoplasms	15%
93	Pancreatic Fistula	14.9%
94	Barrett Esophagus	14.8%
95	Deglutition Disorders	14.8%
96	Achlorhydria	14.6%
97	Gastric Antral Vascular Ectasia	14.6%
98	Peptic Ulcer Hemorrhage	14.5%
99	Gastroparesis	14.5%
100	Giardiasis	14%
101	Pouchitis	13.8%
102	Anal Fissure	13.5%
103	Intestinal Pseudo-Obstruction	13.5%
104	Irritable Bowel Syndrome	13.5%
105	Superior Mesenteric Artery Syndrome	13.5%
106	Neurogenic Bowel	13.5%
107	Anal Ulcer	13.5%
108	Peritoneal Neoplasms	12.8%
109	Diverticulitis	12.5%
110	Melena	12.3%
111	Hematemesis	12.1%
112	Peutz-Jeghers Syndrome	11.8%
113	Lactose Intolerance	11.7%
114	Pancreatic Neoplasm	11.3%
115	Bile Duct Diseases	11%
116	Cholelithiasis	11%
117	Chylous Ascites	11%
118	Fatty Liver	11%
119	Hepatitis	11%
120	Portal Hypertension	11%
121	Intestinal Diseases	11%
122	Liver Cirrhosis	11%
123	Pancreatic Insufficiency	11%
124	Pancreatitis	11%
125	Pneumoperitoneum	11%
126	Focal Nodular Hyperplasia	11%
127	Hepatic Insufficiency	11%
128	Steatohepatitis	11%
129	Pruritus Ani	10.9%
130	Esophageal motility disorders	10.8%
131	Mallory-Weiss Syndrome	10.8%
132	Pyloric Stenosis	10.8%
133	Diverticulum	10.6%
134	Diverticulosis	10.6%
135	Bile Duct Neoplasms	10.4%
136	gallbladder neoplasm	10.4%
137	Choledochal Cyst	10%
138	Cholecystolithiasis	9.7%
139	Biliary cirrhosis	9.7%
140	Cryptosporidiosis	9.3%
141	Liver Diseases, Parasitic	9.2%
142	Hepatic Veno-Occlusive Disease	9%
143	Pancreatic Cyst	9%
144	Peliosis Hepatis	9%
145	Hepatopulmonary Syndrome	9%
146	Anus, Imperforate	8.9%
147	Hemoperitoneum	8.9%
148	Hepatomegaly	8.9%
149	Mesenteric Panniculitis	8.9%
150	Panniculitis, Peritoneal	8.9%
151	Peritonitis	8.9%
152	Peritoneal Fibrosis	8.9%
153	Encapsulating Peritoneal Sclerosis	8.9%
154	Anorectal Malformations	8.9%
155	Biliary Fistula	8.8%
156	Gastric Fistula	8.8%
157	Hepatic Vein Thrombosis	8.8%
158	Liver Abscess	8.8%
159	Budd-Chiari Syndrome	8.8%
160	Dumping Syndrome	8.6%
161	Fatty Liver, Alcoholic	8.1%
162	Hepatitis, Alcoholic	8.1%
163	Liver Cirrhosis, Alcoholic	8.1%
164	Choledocholithiasis	7.7%
165	Chemical and Drug Induced Liver Injury	7.6%
166	Hepatorenal Syndrome	7.4%
167	Esophageal Achalasia	7.1%
168	Hepatocellular Adenoma	6.9%
169	Cystic Fibrosis	6.5%
170	Porphyrias, Hepatic	6.4%
171	Congenital Hyperinsulinism	6.4%
172	Liver Abscess, Amebic	6.1%
173	Liver Neoplasms, Experimental	6.1%
174	Cholangitis	6%
175	Cholecystitis	6%
176	Cholestasis	6%
177	Common Bile Duct Diseases	6%
178	Hepatitis, Chronic	6%
179	Liver Failure	6%
180	Pancreatitis, Chronic	6%
181	Non-alcoholic Fatty Liver Disease	6%
182	Chronic active hepatitis	6%
183	Hepatitis, Animal	5.1%
184	Hepatitis, Viral, Human	5.1%
185	Liver Cirrhosis, Experimental	4.9%
186	Pancreatic Pseudocyst	4.9%
187	Carcinoma, Pancreatic Ductal	4.8%
188	Pancreatitis, Alcoholic	4.8%
189	Laryngopharyngeal Reflux	4.4%
190	Fascioliasis	4.1%
191	Echinococcosis, Hepatic	4.1%
192	Chemical and Drug Induced Liver Injury, Chronic	4.1%
193	Reye Syndrome	4%
194	Cholestasis, Extrahepatic	3.6%
195	Biliary Dyskinesia	3.6%
196	Cholangitis, Sclerosing	3.6%
197	Liver Failure, Acute	3.6%
198	Acalculous Cholecystitis	3.6%
199	End Stage Liver Disease	3.6%
200	Nesidioblastosis	3.4%
201	Variegate Porphyria	3.4%
202	Acute intermittent porphyria	3.4%
203	Porphyria Cutanea Tarda	3.4%
204	Hepatitis B, Chronic	3.4%
205	Hepatitis C, Chronic	3.4%
206	Zellweger Syndrome	3.4%
207	CREST Syndrome	3.2%
208	insulinoma	3.2%
209	Gastrinoma	3.2%
210	Glucagonoma	3.2%
211	Hepatolenticular Degeneration	3.1%
212	Autoimmune hepatitis	2.9%
213	Vipoma	2.9%
214	Hepatitis, Viral, Animal	2.5%
215	Hepatitis E	2.5%
216	Hepatitis B	2.5%
217	Hepatitis C	2.5%
218	Hepatitis A	2.4%
219	Hepatic Encephalopathy	2.4%
220	Massive Hepatic Necrosis	2.4%
221	Emphysematous Cholecystitis	2.4%
222	Sphincter of Oddi Dysfunction	2.4%
223	Rift Valley Fever	1.1%

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