Doxycycline
(FZKWRPSUNUOXKJ-CVHRZJFOSA-N)
Structure
- SMILES
- CN([C@@H]1C(=O)C(=C([C@@]2([C@H]1[C@@H](O)[C@@H]1[C@@H](C)c3cccc(c3C(=C1C2=O)O)O)O)O)C(=O)N)C.O
- Molecular Formula:
- C22H26N2O9
- Molecular Weight:
- 462.450
- Log P:
- 0.1318
- Hydrogen Bond Acceptor:
- 11
- Hydrogen Bond Donor:
- 7
- TPSA:
- 190.85
- CAS Number(s):
- 564-25-0; 17086-28-1
Synonym(s)
1.
Doxycycline
2.
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6alpha,12aalpha))-
3.
Alpha-6-Deoxyoxytetracycline
4.
Atridox
5.
BMY-28689
6.
BU-3839T
7.
Doryx
8.
Doxycycline Calcium
9.
Doxycycline Calcium Salt (1:2)
10.
Doxycycline Hemiethanolate
11.
Doxycycline Hyclate
12.
Doxycycline Monohydrate
13.
Doxycycline Monohydrochloride, 6-epimer
14.
Doxycycline Monohydrochloride, Dihydrate
15.
Doxycycline Phosphate (1:1)
16.
Doxycycline-Chinoin
17.
Hydramycin
18.
Oracea
19.
Periostat
20.
Vibra-Tabs
21.
Vibramycin
22.
Vibramycin Novum
23.
Vibravenos
24.
Alpha 6 Deoxyoxytetracycline
25.
BMY 28689
26.
BMY28689
27.
BU 3839T
28.
BU3839T
29.
Doxycycline Chinoin
30.
Doxycycline Monohydrochloride, 6 epimer
31.
Vibra Tabs
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Headache | FAERS: 16 | US FAERS | |
| 2 | Malaise | FAERS: 13 | US FAERS | |
| 3 | Nausea | FAERS: 9 | US FAERS | |
| 4 | Pain | FAERS: 8 | US FAERS | |
| 5 | Vomiting | FAERS: 8 | US FAERS | |
| 6 | Pruritus | FAERS: 7 | US FAERS | |
| 7 | Fatigue | FAERS: 6 | US FAERS | |
| 8 | Myalgia | FAERS: 6 | US FAERS | |
| 9 | Tinnitus | FAERS: 6 | US FAERS | |
| 10 | Dyspepsia | FAERS: 5 | US FAERS | |
| 11 | Urticaria | FAERS: 5 | US FAERS | |
| 12 | Abdominal Pain | FAERS: 4 | US FAERS | |
| 13 | Anxiety | FAERS: 4 | US FAERS | |
| 14 | Arthralgia | FAERS: 4 | US FAERS | |
| 15 | Asthenia | FAERS: 4 | US FAERS | |
| 16 | Chills | FAERS: 4 | US FAERS | |
| 17 | Dizziness | FAERS: 3 | US FAERS | |
| 18 | Ear discomfort | FAERS: 3 | US FAERS | |
| 19 | Erythema | FAERS: 3 | US FAERS | |
| 20 | Hyperacusis | FAERS: 3 | US FAERS | |
| 21 | Hypersensitivity | FAERS: 3 | US FAERS | |
| 22 | Oropharyngeal pain | FAERS: 3 | US FAERS | |
| 23 | Rash erythematous | FAERS: 3 | US FAERS | |
| 24 | Syncope | FAERS: 3 | US FAERS | |
| 25 | jaundice | FAERS: 3 | US FAERS | |
| 26 | Burning sensation | FAERS: 2 | US FAERS | |
| 27 | Diplopia | FAERS: 2 | US FAERS | |
| 28 | Drug ineffective | FAERS: 2 | US FAERS | |
| 29 | Eye pain | FAERS: 2 | US FAERS | |
| 30 | Food aversion | FAERS: 2 | US FAERS | |
| 31 | Genital infection fungal | FAERS: 2 | US FAERS | |
| 32 | Nail pigmentation | FAERS: 2 | US FAERS | |
| 33 | Peripheral swelling | FAERS: 2 | US FAERS | |
| 34 | Rhabdomyolysis | FAERS: 2 | US FAERS | |
| 35 | Abnormal sleep-related event | FAERS: 1 | US FAERS | |
| 36 | Anosmia | FAERS: 1 | US FAERS | |
| 37 | Autoimmune hepatitis | FAERS: 1 | US FAERS | |
| 38 | Back Pain | FAERS: 1 | US FAERS | |
| 39 | Cardiac Arrest | FAERS: 1 | US FAERS | |
| 40 | Chest Pain | FAERS: 1 | US FAERS | |
| 41 | Chest discomfort | FAERS: 1 | US FAERS | |
| 42 | Cholestasis | FAERS: 1 | US FAERS | |
| 43 | Cold sweat | FAERS: 1 | US FAERS | |
| 44 | Conversion disorder | FAERS: 1 | US FAERS | |
| 45 | Dehydration | FAERS: 1 | US FAERS | |
| 46 | Depressed mood | FAERS: 1 | US FAERS | |
| 47 | Discomfort | FAERS: 1 | US FAERS | |
| 48 | Drug ineffective for unapproved indication | FAERS: 1 | US FAERS | |
| 49 | Drug prescribing error | FAERS: 1 | US FAERS | |
| 50 | Dysphonia | FAERS: 1 | US FAERS | |
| 51 | Dysuria | FAERS: 1 | US FAERS | |
| 52 | Ecchymosis | FAERS: 1 | US FAERS | |
| 53 | Epistaxis | FAERS: 1 | US FAERS | |
| 54 | Exfoliative rash | FAERS: 1 | US FAERS | |
| 55 | Facial Pain | FAERS: 1 | US FAERS | |
| 56 | Facial paralysis | FAERS: 1 | US FAERS | |
| 57 | Feeling Cold | FAERS: 1 | US FAERS | |
| 58 | Feeling of body temperature change | FAERS: 1 | US FAERS | |
| 59 | Feelings of worthlessness | FAERS: 1 | US FAERS | |
| 60 | Fibromyalgia | FAERS: 1 | US FAERS | |
| 61 | Fixed eruption | FAERS: 1 | US FAERS | |
| 62 | Flatulence | FAERS: 1 | US FAERS | |
| 63 | Foreign body in respiratory tract | FAERS: 1 | US FAERS | |
| 64 | Gastrointestinal Pain | FAERS: 1 | US FAERS | |
| 65 | Hepatic necrosis | FAERS: 1 | US FAERS | |
| 66 | Hepatitis | FAERS: 1 | US FAERS | |
| 67 | Hepatotoxicity | FAERS: 1 | US FAERS | |
| 68 | Hypobarism | FAERS: 1 | US FAERS | |
| 69 | Inflammation | FAERS: 1 | US FAERS | |
| 70 | Intentional product misuse | FAERS: 1 | US FAERS | |
| 71 | Intracranial Hypotension | FAERS: 1 | US FAERS | |
| 72 | Lactose Intolerance | FAERS: 1 | US FAERS | |
| 73 | Leukopenia | FAERS: 1 | US FAERS | |
| 74 | Lip swelling | FAERS: 1 | US FAERS | |
| 75 | Lower respiratory tract infection | FAERS: 1 | US FAERS | |
| 76 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 77 | Mouth swelling | FAERS: 1 | US FAERS | |
| 78 | Neck Pain | FAERS: 1 | US FAERS | |
| 79 | Negative thoughts | FAERS: 1 | US FAERS | |
| 80 | Nervousness | FAERS: 1 | US FAERS | |
| 81 | Neurosyphilis | FAERS: 1 | US FAERS | |
| 82 | Onychalgia | FAERS: 1 | US FAERS | |
| 83 | Onycholysis | FAERS: 1 | US FAERS | |
| 84 | Oral candidiasis | FAERS: 1 | US FAERS | |
| 85 | Oral pain | FAERS: 1 | US FAERS | |
| 86 | Pain of skin | FAERS: 1 | US FAERS | |
| 87 | Palpitations | FAERS: 1 | US FAERS | |
| 88 | Pancytopenia | FAERS: 1 | US FAERS | |
| 89 | Paranoia | FAERS: 1 | US FAERS | |
| 90 | Penile swelling | FAERS: 1 | US FAERS | |
| 91 | Photophobia | FAERS: 1 | US FAERS | |
| 92 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 93 | Product use issue | FAERS: 1 | US FAERS | |
| 94 | Pseudoporphyria | FAERS: 1 | US FAERS | |
| 95 | Pulmonary Embolism | FAERS: 1 | US FAERS | |
| 96 | Shock | FAERS: 1 | US FAERS | |
| 97 | Sinus Tachycardia | FAERS: 1 | US FAERS | |
| 98 | Somnolence | FAERS: 1 | US FAERS | |
| 99 | Sunburn | FAERS: 1 | US FAERS | |
| 100 | Supraventricular tachycardia | FAERS: 1 | US FAERS | |
| 101 | Swelling | FAERS: 1 | US FAERS | |
| 102 | Toxicity to various agents | FAERS: 1 | US FAERS | |
| 103 | Tremor | FAERS: 1 | US FAERS | |
| 104 | Vertigo | FAERS: 1 | US FAERS | |
| 105 | Visual Impairment | FAERS: 1 | US FAERS | |
| 106 | Weight decreased | FAERS: 1 | US FAERS |
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