MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hepatitis B, Chronic

(UMLS:C0524909)

Definition:: INFLAMMATION of the LIVER in humans caused by HEPATITIS B VIRUS lasting six months or more. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
UMLS ID:: C0524909
MeSH ID:: D019694

Classification 1:

Name:

Virus Diseases
MeSH Tree Number(s):: C02.256.430.400.100|C02.440.435.100

Classification 2:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.552.380.350.100|C06.552.380.705.437.100

Synonym(s)

Hepatitis B, Chronic

Chronic hepatitis B

Chronic type B viral hepatitis

Chronic viral hepatitis B

HEPATITIS B CHRONIC

HEPATITIS, CHRONIC TYPE B

chronic hep b

chronic hepatitis B infection

chronic hepatitis b

10.

chronic hepatitis, B virus

11.

chronic viral hepatitis B infection

12.

hepatitis b chronic

13.

hepatitis b chronic viral

14.

hepatitis; virus, chronic, type B

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Clevudine	19581770	CTD
2	Colchicine	9701529	CTD
3	Cyclosporine	7657365	CTD
4	Everolimus	17346627	CTD
5	Famciclovir	11792996	CTD
6	Lamivudine	View details 7475613 9314118 9654535 9721816 10051494 10333144 10462384 10707871 10861652 10889166 11003363 11003633 11084057 11176135 11227671 11480792 11738102 11951067 12044531 12116023 12126723 12143063 12167344 12454840 12483247 12558905 12627352 12634582 12665914 12681069 12763376 12802750 12879950 14552720 14614664 14688454 14699491 14724824 14756274 14969833 14974368 15017612 15274664 15309715 15336449 15340535 15371578 15504290 15631357 15714490 15740536 15915463 16224157 16246192 16250037 16386595 16476009 16688836 16762627 16810760 16842441 16927289 16944240 16988516 17256746 17302259 17607775 17637268 17683493 17713159 17713642 17983801 17988233 18159148 18279995 18350610 18433925 18492018 19070393 19302908 19346146 19387534 19455108 19457141 19602924 19669266 19669311 19780875 19785947 19818142 19912686 20498322 20659226 20729619 20872709 21186528	CTD
7	Levamisole	10626183	CTD
8	Prednisolone	3781203	CTD
9	Prednisone	View details 1669052 7608474 8097249 20944818	CTD
10	Ribavirin	15751770 18756437	CTD
11	Telbivudine	View details 18159148 18201580 18798704 19225726 19302908	CTD
12	Tenofovir	View details 12143063 15017612 16871563 16988516 19602924 19669311	CTD
13	Thymopentin	12665914	CTD
14	Vidarabine Phosphate	9646223	CTD
15	Vidarabine	3781203 8097249	CTD
16	adefovir dipivoxil	View details 10869300 12143057 12962817 14647053 14699491 14756274 14997399 15125374 15655050 15740536 15915463 16224157 16278590 16386595 16699864 16729316 16842441 17087951 17196132 17256746 17400303 17431777 17561304 17637268 17683493 17713159 17898551 17983801 17988233 18279995 18433925 18572751 18971179 19119245 19222742 19302908 19346785 19387534 19602924 19669266 19704174 19780875 19818142 19912686 20386079 20498322 20558919	CTD
17	adefovir	View details 16338024 18350610 18367858 19152409 19346146 19712848 20332649 20559524 20659226 20729619 20872709	CTD
18	alfuzosin	15280514	CTD
19	entecavir	View details 12454840 16762627 17244451 17653304 17917412 18537189 18554238 19070393 19226381 19457141 19669332 19704174 20305760 20659226 21186528	CTD
20	oxymatrine	15340535	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hepatitis C, Chronic	34.8%
2	Hepatitis E	33.5%
3	Hepatitis C	31.3%
4	Hepatitis A	30.2%
5	Hepatitis, Alcoholic	25.6%
6	Autoimmune hepatitis	22.2%
7	Hepatitis, Animal	21.7%
8	Hepatitis, Viral, Animal	21.1%
9	Fatty Liver	18.8%
10	Portal Hypertension	18.8%
11	Liver Cirrhosis	18.8%
12	Focal Nodular Hyperplasia	18.8%
13	Hepatic Insufficiency	18.8%
14	Steatohepatitis	18.8%
15	Liver neoplasms	18.1%
16	Rift Valley Fever	17.8%
17	Hepatitis, Viral, Human	16.9%
18	Biliary cirrhosis	16.5%
19	Liver Diseases, Parasitic	16.2%
20	Hepatic Veno-Occlusive Disease	15.9%
21	Peliosis Hepatis	15.9%
22	Hepatopulmonary Syndrome	15.9%
23	Hepatomegaly	15.7%
24	Hepatic Vein Thrombosis	15.6%
25	Liver Abscess	15.6%
26	Budd-Chiari Syndrome	15.6%
27	Fatty Liver, Alcoholic	15.3%
28	Liver Cirrhosis, Alcoholic	15.3%
29	Warts	14.6%
30	Herpesviridae Infections	13.9%
31	Polyomavirus Infections	13.9%
32	Chemical and Drug Induced Liver Injury	13.7%
33	Hepatorenal Syndrome	13.4%
34	Epstein-Barr Virus Infections	13.2%
35	Arbovirus Infections	12.9%
36	Liver Abscess, Amebic	12.1%
37	Esophageal and Gastric Varices	12%
38	Biliary Tract Diseases	11.9%
39	Gastrointestinal Diseases	11.9%
40	Pancreatic Diseases	11.9%
41	Porphyrias, Hepatic	11.8%
42	Hepatitis, Chronic	11.4%
43	Chronic active hepatitis	11.4%
44	Molluscum Contagiosum	11.3%
45	Hepatitis B, Chronic	10.9%
46	Condylomata Acuminata	10.9%
47	Dengue Fever	10.8%
48	Hepatitis B	10.8%
49	Yellow Fever	10.8%
50	Liver Failure	10.7%
51	Non-alcoholic Fatty Liver Disease	10.7%
52	Leukoencephalopathy, Progressive Multifocal	10.7%
53	Viremia	10.6%
54	Pseudorabies	10.1%
55	Digestive System Neoplasms	10%
56	Phlebotomus Fever	9.9%
57	Erythema Infectiosum	9.9%
58	Hemorrhagic Fever, Crimean	9.8%
59	Subacute Sclerosing Panencephalitis	9.7%
60	Opportunistic Infections	9.5%
61	Epidermodysplasia Verruciformis	9.3%
62	Pneumonia, Viral	9.2%
63	Gastrointestinal Neoplasms	9.1%
64	Pancreatic Fistula	9%
65	Liver Cirrhosis, Experimental	9%
66	Hepatocellular Adenoma	9%
67	Zika Virus Infection	8.8%
68	Murine Acquired Immunodeficiency Syndrome	8.6%
69	Cytomegalovirus Infections	8.5%
70	Smallpox	8.5%
71	Varicella Zoster Virus Infection	8.5%
72	Herpes Zoster Ophthalmicus	8.5%
73	West Nile Fever	8.4%
74	Zollinger-Ellison syndrome	8.3%
75	Keratitis, Herpetic	8.2%
76	Cytomegalovirus Retinitis	8.2%
77	Exanthema Subitum	8.2%
78	Acquired Immunodeficiency Syndrome	8.2%
79	AIDS related complex	8.2%
80	Chronic Fatigue Syndrome	8.1%
81	Sexually Transmitted Diseases	8.1%
82	Liver Neoplasms, Experimental	8%
83	Peritoneal Neoplasms	7.9%
84	Fascioliasis	7.8%
85	Echinococcosis, Hepatic	7.8%
86	Chemical and Drug Induced Liver Injury, Chronic	7.7%
87	Reye Syndrome	7.7%
88	Hemorrhagic Fever, American	7.6%
89	Lassa Fever	7.6%
90	Simian Acquired Immunodeficiency Syndrome	7.5%
91	Eczema Herpeticum	7.4%
92	Orthomyxoviridae Infections	7.3%
93	Picornaviridae Infections	7.3%
94	Reoviridae Infections	7.3%
95	Retroviridae Infections	7.3%
96	Mesenteric vascular insufficiency	7.2%
97	Pancreatic Neoplasm	7.1%
98	Esophageal Atresia	7.1%
99	Intestinal Atresia	7.1%
100	Mesenteric Vascular Occlusion	7.1%
101	Intestinal Fistula	7.1%
102	Enterocutaneous Fistula	7.1%
103	Liver Failure, Acute	6.8%
104	End Stage Liver Disease	6.8%
105	Bile Duct Neoplasms	6.7%
106	gallbladder neoplasm	6.7%
107	Intestinal Neoplasms	6.7%
108	Stomach Neoplasms	6.7%
109	Variegate Porphyria	6.7%
110	Acute intermittent porphyria	6.7%
111	Porphyria Cutanea Tarda	6.7%
112	Zellweger Syndrome	6.6%
113	Genital Herpes	6.6%
114	Hemorrhagic Fever with Renal Syndrome	6.5%
115	Herpes Labialis	6.5%
116	Bile Duct Diseases	6.3%
117	Cholelithiasis	6.3%
118	Chylous Ascites	6.3%
119	Esophageal Diseases	6.3%
120	Gastroenteritis	6.3%
121	Intestinal Diseases	6.3%
122	Pancreatic Insufficiency	6.3%
123	Pancreatitis	6.3%
124	Pneumoperitoneum	6.3%
125	Stomach Diseases	6.3%
126	Choledochal Cyst	6.3%
127	Hepatolenticular Degeneration	6.2%
128	Esophageal Neoplasms	6%
129	Dysentery	6%
130	Enteritis	6%
131	Enterocolitis	6%
132	Esophagitis	6%
133	Gastritis	6%
134	Inflammatory Bowel Diseases	6%
135	Cholecystolithiasis	6%
136	Chickenpox	5.8%
137	Burkitt Lymphoma	5.7%
138	HIV Infections	5.6%
139	Colorectal Neoplasms	5.6%
140	AIDS-Related Opportunistic Infections	5.5%
141	Bell Palsy	5.4%
142	Pancreatic Cyst	5.3%
143	Superinfection	5.3%
144	Anus, Imperforate	5.2%
145	Gastrointestinal Hemorrhage	5.2%
146	Hemoperitoneum	5.2%
147	Mesenteric Panniculitis	5.2%
148	Panniculitis, Peritoneal	5.2%
149	Peritonitis	5.2%
150	Peritoneal Fibrosis	5.2%
151	Encapsulating Peritoneal Sclerosis	5.2%
152	Anorectal Malformations	5.2%
153	Biliary Fistula	5.2%
154	Gastric Fistula	5.2%
155	Tuberculosis, Gastrointestinal	5.2%
156	Proctocolitis	5.2%
157	Gastrointestinal Stromal Tumors	5.1%
158	Rectal Fistula	5.1%
159	Anal Fistula	5.1%
160	Cecal Neoplasms	5%
161	Duodenal Neoplasms	5%
162	Colitis	4.9%
163	Duodenogastric Reflux	4.9%
164	Peptic Ulcer	4.9%
165	Proctitis	4.9%
166	Choledocholithiasis	4.9%
167	Hepatic Encephalopathy	4.9%
168	Duodenitis	4.8%
169	Ileitis	4.8%
170	Erosive Duodenitis	4.8%
171	Massive Hepatic Necrosis	4.8%
172	Enterovirus Infections	4.6%
173	Flavivirus Infections	4.6%
174	Paramyxoviridae Infections	4.6%
175	Cardiovirus Infections	4.6%
176	Rhabdoviridae Infections	4.6%
177	Herpangina	4.3%
178	Appendicitis	4.2%
179	HIV Seropositivity	4.2%
180	Cystic Fibrosis	4%
181	Foot-and-Mouth Disease	3.9%
182	Congenital Hyperinsulinism	3.9%
183	Common Cold	3.9%
184	Influenza	3.9%
185	Catarrh	3.9%
186	Crohn Disease	3.8%
187	Duodenal Obstruction	3.8%
188	Enterocolitis, Neutropenic	3.8%
189	Necrotizing Enterocolitis	3.8%
190	Infectious Mononucleosis	3.7%
191	Cecal Diseases	3.6%
192	Cholangitis	3.6%
193	Cholecystitis	3.6%
194	Cholestasis	3.6%
195	Colonic Diseases	3.6%
196	Common Bile Duct Diseases	3.6%
197	Esophageal Stenosis	3.6%
198	Ileal Diseases	3.6%
199	Intestinal Obstruction	3.6%
200	Intestinal Perforation	3.6%
201	Jejunal Diseases	3.6%
202	Pneumatosis Cystoides Intestinalis	3.6%
203	Rectal Diseases	3.6%
204	Gastric Dilatation	3.6%
205	Pancreatitis, Chronic	3.6%
206	Gastric outlet obstruction	3.6%
207	Cronkhite-Canada Syndrome	3.6%
208	Intestinal Polyposis	3.6%
209	Appendiceal Neoplasms	3.6%
210	Colonic Neoplasms	3.6%
211	Rectal Neoplasms	3.6%
212	Pouchitis	3.4%
213	Adenomatous Polyposis Coli	3.4%
214	Anus Neoplasms	3.3%
215	Sigmoid Neoplasms	3.3%
216	HIV Wasting Syndrome	3.3%
217	AIDS Dementia Complex	3.2%
218	AIDS-Associated Nephropathy	3.2%
219	Carcinoma, Pancreatic Ductal	3.2%
220	Coxsackievirus Infections	3.2%
221	Rubella	3.2%
222	Coronavirus Infections	3.2%
223	Nipah Virus Infection	3.2%
224	Hydrophobia	3.2%
225	Enterocolitis, Pseudomembranous	3.2%
226	pseudomembranous colitis	3.2%
227	Dysentery, Bacillary	3.2%
228	Duodenal Ulcer	3.2%
229	Peptic Ulcer Perforation	3.2%
230	Gastric ulcer	3.2%
231	Esophageal Perforation	3.1%
232	Intestinal Diseases, Parasitic	3.1%
233	Barrett Esophagus	3%
234	Deglutition Disorders	3%
235	Achlorhydria	3%
236	Pancreatic Pseudocyst	3%
237	Gastric Antral Vascular Ectasia	3%
238	Peptic Ulcer Hemorrhage	3%
239	Gastroparesis	3%
240	Pancreatitis, Alcoholic	3%
241	HIV-Associated Lipodystrophy Syndrome	2.9%
242	Herpes Zoster Oticus	2.9%
243	Colitis, Ischemic	2.8%
244	Porcine Reproductive and Respiratory Syndrome	2.7%
245	HTLV-I Infections	2.7%
246	Melena	2.6%
247	Measles	2.6%
248	Pleurodynia, Epidemic	2.6%
249	Respiratory Syncytial Virus Infections	2.6%
250	Hematemesis	2.6%
251	Colonic Pseudo-Obstruction	2.4%
252	Vesicular Stomatitis	2.4%
253	Cholestasis, Extrahepatic	2.3%
254	Biliary Dyskinesia	2.3%
255	Cholangitis, Sclerosing	2.3%
256	Colonic Diseases, Functional	2.3%
257	Esophageal motility disorders	2.3%
258	Fecal Incontinence	2.3%
259	Fecal Impaction	2.3%
260	Intussusception	2.3%
261	Mallory-Weiss Syndrome	2.3%
262	Megacolon	2.3%
263	Pyloric Stenosis	2.3%
264	Acalculous Cholecystitis	2.3%
265	Ileus	2.3%
266	Meconium ileus	2.3%
267	insulinoma	2.3%
268	Gastrinoma	2.2%
269	Glucagonoma	2.2%
270	Nesidioblastosis	2.2%
271	Gastroenteritis, Transmissible, of Swine	2.2%
272	Severe Acute Respiratory Syndrome	2.2%
273	Mumps	2.1%
274	Poliomyelitis	2%
275	Vipoma	2%
276	Hemorrhoids	1.9%
277	Afferent Loop Syndrome	1.9%
278	Celiac Disease	1.9%
279	Short Bowel Syndrome	1.9%
280	Sprue, Tropical	1.9%
281	Steatorrhea	1.9%
282	Rectocele	1.9%
283	Sprue	1.9%
284	Diverticulitis	1.9%
285	Dumping Syndrome	1.9%
286	Rectal Prolapse	1.9%
287	Giardiasis	1.7%
288	Diverticulum	1.6%
289	Diverticulosis	1.6%
290	Esophageal Achalasia	1.6%
291	Anal Fissure	1.6%
292	Intestinal Pseudo-Obstruction	1.6%
293	Irritable Bowel Syndrome	1.6%
294	Superior Mesenteric Artery Syndrome	1.6%
295	Emphysematous Cholecystitis	1.6%
296	Neurogenic Bowel	1.6%
297	Sphincter of Oddi Dysfunction	1.6%
298	Anal Ulcer	1.6%
299	Peutz-Jeghers Syndrome	1.4%
300	Lactose Intolerance	1.4%
301	Pruritus Ani	1.4%
302	Cryptosporidiosis	1.2%
303	Laryngopharyngeal Reflux	1.1%
304	CREST Syndrome	0.8%

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