MetaADEDB 2.0 @ LMMD
Metoprolol
(RGHAZVBIOOEVQX-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)CCC(=O)O.COCCc1ccc(cc1)OCC(CNC(C)C)O.COCCc1ccc(cc1)OCC(CNC(C)C)O
Molecular Formula:
C34H56N2O10
Molecular Weight:
652.816
Log P:
3.9440
Hydrogen Bond Acceptor:
12
Hydrogen Bond Donor:
6
TPSA:
176.04
CAS Number(s):
98418-47-4
Synonym(s)
1.
Metoprolol
2.
Beloc-Duriles
3.
Betaloc
4.
Betaloc-Astra
5.
Betalok
6.
CGP-2175
7.
H 93-26
8.
Lopressor
9.
Metoprolol CR-XL
10.
Metoprolol Succinate
11.
Metoprolol Tartrate
12.
Seloken
13.
Spesicor
14.
Spesikor
15.
Toprol
16.
Toprol-XL
17.
Beloc Duriles
18.
Betaloc Astra
19.
CGP 2175
20.
CGP2175
21.
H 93 26
22.
H 9326
23.
Metoprolol CR XL
24.
Toprol XL
External Link(s)
MeSHD008790
PubChem Compound62937
ChEBI6905
CHEMBLCHEMBL2356097
KEGGdr:D00635
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 171US FAERS
2MalaiseFAERS: 129US FAERS
3DizzinessFAERS: 103US FAERS
4Product substitution issueFAERS: 93US FAERS
5PalpitationsFAERS: 92US FAERS
6HeadacheFAERS: 91US FAERS
7Product quality issueFAERS: 83US FAERS
8Drug dose omissionFAERS: 75US FAERS
9Feeling abnormalFAERS: 64US FAERS
10FatigueFAERS: 54US FAERS
11NauseaFAERS: 50US FAERS
12AnxietyFAERS: 44US FAERS
13Adverse eventFAERS: 40US FAERS
14BradycardiaFAERS: 37US FAERS
15HypotensionFAERS: 36US FAERS
16Chest PainFAERS: 35US FAERS
17Blood pressure inadequately controlledFAERS: 33US FAERS
18AstheniaFAERS: 32US FAERS
19Chest discomfortFAERS: 29US FAERS
20Therapeutic response unexpected with drug substitutionFAERS: 29US FAERS
21HypersensitivityFAERS: 28US FAERS
22Myocardial InfarctionFAERS: 28US FAERS
23Atrial FibrillationFAERS: 25US FAERS
24PruritusFAERS: 25US FAERS
25AlopeciaFAERS: 24US FAERS
26Intentional drug misuseFAERS: 24US FAERS
27Inappropriate schedule of drug administrationFAERS: 23US FAERS
28TachycardiaFAERS: 23US FAERS
29Blood pressure fluctuationFAERS: 22US FAERS
30Cerebrovascular accidentFAERS: 22US FAERS
31PainFAERS: 22US FAERS
32Intentional product misuseFAERS: 20US FAERS
33TremorFAERS: 20US FAERS
34Visual ImpairmentFAERS: 20US FAERS
35Pharmaceutical product complaintFAERS: 19US FAERS
36SyncopeFAERS: 18US FAERS
37Toxicity to various agentsFAERS: 18US FAERS
38Unevaluable eventFAERS: 18US FAERS
39SomnolenceFAERS: 17US FAERS
40Abdominal discomfortFAERS: 16US FAERS
41Diabetes MellitusFAERS: 16US FAERS
42Product use issueFAERS: 16US FAERS
43AsthmaFAERS: 15US FAERS
44TinnitusFAERS: 14US FAERS
45Activities of daily living impairedFAERS: 13US FAERS
46DyspepsiaFAERS: 13US FAERS
47Inappropriate schedule of product administrationFAERS: 13US FAERS
48NasopharyngitisFAERS: 13US FAERS
49NervousnessFAERS: 13US FAERS
50StressFAERS: 13US FAERS
51Angina PectorisFAERS: 12US FAERS
52Completed SuicideFAERS: 12US FAERS
53Memory impairmentFAERS: 12US FAERS
54VomitingFAERS: 12US FAERS
55Wrong technique in product usage processFAERS: 12US FAERS
56Abdominal PainFAERS: 11US FAERS
57ArthralgiaFAERS: 11US FAERS
58PneumoniaFAERS: 11US FAERS
59Drug ineffective for unapproved indicationFAERS: 10US FAERS
60OverdoseFAERS: 10US FAERS
61ConstipationFAERS: 9US FAERS
62Drug dispensing errorFAERS: 9US FAERS
63FlatulenceFAERS: 9US FAERS
64Medication ErrorFAERS: 9US FAERS
65Suicide attemptFAERS: 9US FAERS
66SwellingFAERS: 9US FAERS
67Weight decreasedFAERS: 9US FAERS
68DiscomfortFAERS: 8US FAERS
69DisorientationFAERS: 8US FAERS
70DysgeusiaFAERS: 8US FAERS
71Joint swellingFAERS: 8US FAERS
72UrticariaFAERS: 8US FAERS
73Burning sensationFAERS: 7US FAERS
74Cardiac FlutterFAERS: 7US FAERS
75ErythemaFAERS: 7US FAERS
76Feeling ColdFAERS: 7US FAERS
77Incorrect dose administeredFAERS: 7US FAERS
78Musculoskeletal stiffnessFAERS: 7US FAERS
79Oropharyngeal painFAERS: 7US FAERS
80WheezingFAERS: 7US FAERS
81AngioedemaFAERS: 6US FAERS
82ArthritisFAERS: 6US FAERS
83Atrioventricular BlockFAERS: 6US FAERS
84Back PainFAERS: 6US FAERS
85BronchitisFAERS: 6US FAERS
86Cardiac ArrestFAERS: 6US FAERS
87ChillsFAERS: 6US FAERS
88LethargyFAERS: 6US FAERS
89Medication residueFAERS: 6US FAERS
90Peripheral swellingFAERS: 6US FAERS
91PsoriasisFAERS: 6US FAERS
92Reaction to drug excipientsFAERS: 6US FAERS
93Supraventricular tachycardiaFAERS: 6US FAERS
94VertigoFAERS: 6US FAERS
95AmnesiaFAERS: 5US FAERS
96Blood cholesterol increasedFAERS: 5US FAERS
97Circumstance or information capable of leading to medication errorFAERS: 5US FAERS
98Drug effect incompleteFAERS: 5US FAERS
99DysphoniaFAERS: 5US FAERS
100EpistaxisFAERS: 5US FAERS
101EructationFAERS: 5US FAERS
102Impaired work abilityFAERS: 5US FAERS
103MyalgiaFAERS: 5US FAERS
104PresyncopeFAERS: 5US FAERS
105Product dose omissionFAERS: 5US FAERS
106Sinus bradycardiaFAERS: 5US FAERS
107Urinary tract infectionFAERS: 5US FAERS
108Ventricular arrhythmiaFAERS: 5US FAERS
109Wrong drug administeredFAERS: 5US FAERS
110Wrong technique in drug usage processFAERS: 5US FAERS
111AbasiaFAERS: 4US FAERS
112BronchospasmFAERS: 4US FAERS
113CardiotoxicityFAERS: 4US FAERS
114CataractFAERS: 4US FAERS
115Cold sweatFAERS: 4US FAERS
116DeafnessFAERS: 4US FAERS
117DementiaFAERS: 4US FAERS
118Depressed moodFAERS: 4US FAERS
119DiplopiaFAERS: 4US FAERS
120Drug prescribing errorFAERS: 4US FAERS
121Feeling jitteryFAERS: 4US FAERS
122FlushingFAERS: 4US FAERS
123GoutFAERS: 4US FAERS
124InfluenzaFAERS: 4US FAERS
125Lip swellingFAERS: 4US FAERS
126Macular degenerationFAERS: 4US FAERS
127Musculoskeletal PainFAERS: 4US FAERS
128Product solubility abnormalFAERS: 4US FAERS
129Product taste abnormalFAERS: 4US FAERS
130Sinus TachycardiaFAERS: 4US FAERS
131Therapeutic response unexpectedFAERS: 4US FAERS
132AgeusiaFAERS: 3US FAERS
133AngerFAERS: 3US FAERS
134AphoniaFAERS: 3US FAERS
135BlindnessFAERS: 3US FAERS
136Cardiac discomfortFAERS: 3US FAERS
137ChokingFAERS: 3US FAERS
138Coronary Artery DiseaseFAERS: 3US FAERS
139DehydrationFAERS: 3US FAERS
140Drug administration errorFAERS: 3US FAERS
141Ear discomfortFAERS: 3US FAERS
142Eye painFAERS: 3US FAERS
143GlaucomaFAERS: 3US FAERS
144Head discomfortFAERS: 3US FAERS
145HyperthyroidismFAERS: 3US FAERS
146Limb discomfortFAERS: 3US FAERS
147Medication residue presentFAERS: 3US FAERS
148Multiple allergiesFAERS: 3US FAERS
149Neonatal tachycardiaFAERS: 3US FAERS
150Night sweatsFAERS: 3US FAERS
151No adverse eventFAERS: 3US FAERS
152PallorFAERS: 3US FAERS
153Poor quality sleepFAERS: 3US FAERS
154Product formulation issueFAERS: 3US FAERS
155RetchingFAERS: 3US FAERS
156Skin UlcerFAERS: 3US FAERS
157Sleep disorder due to general medical condition, insomnia typeFAERS: 3US FAERS
158ThirstFAERS: 3US FAERS
159Throat irritationFAERS: 3US FAERS
160ThrombosisFAERS: 3US FAERS
161AgitationFAERS: 2US FAERS
162Allergic reaction to excipientFAERS: 2US FAERS
163AlveolitisFAERS: 2US FAERS
164AneurysmFAERS: 2US FAERS
165Aortic AneurysmFAERS: 2US FAERS
166ApathyFAERS: 2US FAERS
167AphagiaFAERS: 2US FAERS
168Apparent deathFAERS: 2US FAERS
169ArthropathyFAERS: 2US FAERS
170AsphyxiaFAERS: 2US FAERS
171Atrial tachycardiaFAERS: 2US FAERS
172Back disorderFAERS: 2US FAERS
173Bladder painFAERS: 2US FAERS
174Blood glucose decreasedFAERS: 2US FAERS
175Bone painFAERS: 2US FAERS
176Bowel movement irregularityFAERS: 2US FAERS
177Counterfeit drug administeredFAERS: 2US FAERS
178CystitisFAERS: 2US FAERS
179Depressed Level of ConsciousnessFAERS: 2US FAERS
180Disease recurrenceFAERS: 2US FAERS
181DiverticulitisFAERS: 2US FAERS
182Drug level fluctuatingFAERS: 2US FAERS
183Dry skinFAERS: 2US FAERS
184DysuriaFAERS: 2US FAERS
185Erectile dysfunctionFAERS: 2US FAERS
186Escherichia infectionFAERS: 2US FAERS
187FibromyalgiaFAERS: 2US FAERS
188GastritisFAERS: 2US FAERS
189General physical health deteriorationFAERS: 2US FAERS
190Gluten sensitivityFAERS: 2US FAERS
191HungerFAERS: 2US FAERS
192Hypertensive crisisFAERS: 2US FAERS
193Initial insomniaFAERS: 2US FAERS
194Intentional dose omissionFAERS: 2US FAERS
195Intentional product use issueFAERS: 2US FAERS
196Intercepted drug dispensing errorFAERS: 2US FAERS
197Lactose IntoleranceFAERS: 2US FAERS
198LaryngitisFAERS: 2US FAERS
199Limb injuryFAERS: 2US FAERS
200Lower respiratory tract infectionFAERS: 2US FAERS
201Mental impairmentFAERS: 2US FAERS
202Mental status changesFAERS: 2US FAERS
203Middle insomniaFAERS: 2US FAERS
204NephrolithiasisFAERS: 2US FAERS
205OverweightFAERS: 2US FAERS
206Pancreatic carcinomaFAERS: 2US FAERS
207Peripheral arterial occlusive diseaseFAERS: 2US FAERS
208PhotophobiaFAERS: 2US FAERS
209Product dispensing errorFAERS: 2US FAERS
210Product use complaintFAERS: 2US FAERS
211Product use in unapproved indicationFAERS: 2US FAERS
212Productive CoughFAERS: 2US FAERS
213Respiratory DepressionFAERS: 2US FAERS
214RestlessnessFAERS: 2US FAERS
215SepsisFAERS: 2US FAERS
216Sick Sinus SyndromeFAERS: 2US FAERS
217Single functional kidneyFAERS: 2US FAERS
218SinusitisFAERS: 2US FAERS
219SluggishnessFAERS: 2US FAERS
220SomnambulismFAERS: 2US FAERS
221TensionFAERS: 2US FAERS
222Therapy non-responderFAERS: 2US FAERS
223jaundiceFAERS: 2US FAERS
224Accidental drug intake by childFAERS: 1US FAERS
225Accidental exposure to productFAERS: 1US FAERS
226AcidosisFAERS: 1US FAERS
227Acute myocardial infarctionFAERS: 1US FAERS
228Alcohol problemFAERS: 1US FAERS
229Allergy to chemicalsFAERS: 1US FAERS
230Altered state of consciousnessFAERS: 1US FAERS
231AnhedoniaFAERS: 1US FAERS
232AnorexiaFAERS: 1US FAERS
233AnosmiaFAERS: 1US FAERS
234AphasiaFAERS: 1US FAERS
235ArteriosclerosisFAERS: 1US FAERS
236Arthropod biteFAERS: 1US FAERS
237Arthropod stingFAERS: 1US FAERS
238AtaxiaFAERS: 1US FAERS
239Atypical pneumoniaFAERS: 1US FAERS
240Autonomic nervous system imbalanceFAERS: 1US FAERS
241BedriddenFAERS: 1US FAERS
242BilirubinuriaFAERS: 1US FAERS
243Blood alkaline phosphatase increasedFAERS: 1US FAERS
244Blood cholesterol abnormalFAERS: 1US FAERS
245Blood creatine phosphokinase MB increasedFAERS: 1US FAERS
246Blood creatine phosphokinase increasedFAERS: 1US FAERS
247Blood glucose increasedFAERS: 1US FAERS
248Blood insulin decreasedFAERS: 1US FAERS
249Blood pressure difference of extremitiesFAERS: 1US FAERS
250Blood pressure immeasurableFAERS: 1US FAERS
251Blood sodium abnormalFAERS: 1US FAERS
252Blood sodium decreasedFAERS: 1US FAERS
253Blood sodium increasedFAERS: 1US FAERS
254Blood testosterone decreasedFAERS: 1US FAERS
255Brain natriuretic peptide increasedFAERS: 1US FAERS
256Breakthrough PainFAERS: 1US FAERS
257BruxismFAERS: 1US FAERS
258Carotid aneurysm ruptureFAERS: 1US FAERS
259Carpal Tunnel SyndromeFAERS: 1US FAERS
260CellulitisFAERS: 1US FAERS
261Cerebral ThrombosisFAERS: 1US FAERS
262ChemotherapyFAERS: 1US FAERS
263CholelithiasisFAERS: 1US FAERS
264Coma scale abnormalFAERS: 1US FAERS
265CryingFAERS: 1US FAERS
266CyanosisFAERS: 1US FAERS
267Decorticate postureFAERS: 1US FAERS
268DeliriumFAERS: 1US FAERS
269Dermatitis HerpetiformisFAERS: 1US FAERS
270Device dislocationFAERS: 1US FAERS
271Device related infectionFAERS: 1US FAERS
272Diabetes mellitus inadequate controlFAERS: 1US FAERS
273Drug ToleranceFAERS: 1US FAERS
274Drug abuseFAERS: 1US FAERS
275Drug effect delayedFAERS: 1US FAERS
276Drug exposure during pregnancyFAERS: 1US FAERS
277Drug screen false positiveFAERS: 1US FAERS
278Drug toxicityFAERS: 1US FAERS
279DysarthriaFAERS: 1US FAERS
280Ear congestionFAERS: 1US FAERS
281EczemaFAERS: 1US FAERS
282Ejection Fraction DecreasedFAERS: 1US FAERS
283Electrocardiogram abnormalFAERS: 1US FAERS
284Electromyogram abnormalFAERS: 1US FAERS
285Embolic strokeFAERS: 1US FAERS
286EncephalitisFAERS: 1US FAERS
287EndometriosisFAERS: 1US FAERS
288Eosinophilic granulomatosis with polyangiitisFAERS: 1US FAERS
289Epigastric discomfortFAERS: 1US FAERS
290Erythema MultiformeFAERS: 1US FAERS
291ErythropsiaFAERS: 1US FAERS
292Excessive eye blinkingFAERS: 1US FAERS
293Exfoliative rashFAERS: 1US FAERS
294Exposure during breast feedingFAERS: 1US FAERS
295External ear painFAERS: 1US FAERS
296Extra dose administeredFAERS: 1US FAERS
297Eye symptomFAERS: 1US FAERS
298Eyelid skin drynessFAERS: 1US FAERS
299Feeling of body temperature changeFAERS: 1US FAERS
300Femoral artery occlusionFAERS: 1US FAERS
301Food AllergyFAERS: 1US FAERS
302Full blood count decreasedFAERS: 1US FAERS
303Gastrointestinal hypomotilityFAERS: 1US FAERS
304General physical condition abnormalFAERS: 1US FAERS
305HemiparesisFAERS: 1US FAERS
306HepatotoxicityFAERS: 1US FAERS
307HerniaFAERS: 1US FAERS
308HypersomniaFAERS: 1US FAERS
309HypogeusiaFAERS: 1US FAERS
310HypokinesiaFAERS: 1US FAERS
311HypothyroidismFAERS: 1US FAERS
312HypoventilationFAERS: 1US FAERS
313HysterectomyFAERS: 1US FAERS
314Inappropriate affectFAERS: 1US FAERS
315IncontinenceFAERS: 1US FAERS
316Incorrect drug administration durationFAERS: 1US FAERS
317Incorrect drug administration rateFAERS: 1US FAERS
318Incorrect route of drug administrationFAERS: 1US FAERS
319Increased upper airway secretionFAERS: 1US FAERS
320InflammationFAERS: 1US FAERS
321Intentional self-injuryFAERS: 1US FAERS
322Intercepted drug prescribing errorFAERS: 1US FAERS
323Intermittent ClaudicationFAERS: 1US FAERS
324Intestinal ObstructionFAERS: 1US FAERS
325Intracranial AneurysmFAERS: 1US FAERS
326Irritable Bowel SyndromeFAERS: 1US FAERS
327Joint Range of Motion DecreasedFAERS: 1US FAERS
328LacerationFAERS: 1US FAERS
329Left ventricular end-diastolic pressure increasedFAERS: 1US FAERS
330Leriche SyndromeFAERS: 1US FAERS
331Ligament ruptureFAERS: 1US FAERS
332Lip exfoliationFAERS: 1US FAERS
333LymphadenopathyFAERS: 1US FAERS
334MastectomyFAERS: 1US FAERS
335Maternal exposure during pregnancyFAERS: 1US FAERS
336MenopauseFAERS: 1US FAERS
337MonoplegiaFAERS: 1US FAERS
338Mood swingsFAERS: 1US FAERS
339Mouth swellingFAERS: 1US FAERS
340Multiple SclerosisFAERS: 1US FAERS
341Muscle SpasticityFAERS: 1US FAERS
342Muscle tightnessFAERS: 1US FAERS
343Myasthenia GravisFAERS: 1US FAERS
344Neonatal disorderFAERS: 1US FAERS
345Nerve injuryFAERS: 1US FAERS
346Neuropsychiatric syndromeFAERS: 1US FAERS
347Non-cardiac chest painFAERS: 1US FAERS
348Nonspecific reactionFAERS: 1US FAERS
349Ocular icterusFAERS: 1US FAERS
350Organic brain syndromeFAERS: 1US FAERS
351Oropharyngeal plaqueFAERS: 1US FAERS
352OsteomyelitisFAERS: 1US FAERS
353OsteopeniaFAERS: 1US FAERS
354Otitis ExternaFAERS: 1US FAERS
355Pacemaker generated rhythmFAERS: 1US FAERS
356Pain of skinFAERS: 1US FAERS
357PancreatitisFAERS: 1US FAERS
358PancytopeniaFAERS: 1US FAERS
359ParanoiaFAERS: 1US FAERS
360Peripheral artery stenosisFAERS: 1US FAERS
361Peripheral venous diseaseFAERS: 1US FAERS
362Physical assaultFAERS: 1US FAERS
363PneumonitisFAERS: 1US FAERS
364PneumothoraxFAERS: 1US FAERS
365PolyuriaFAERS: 1US FAERS
366Poor peripheral circulationFAERS: 1US FAERS
367Poor quality drug administeredFAERS: 1US FAERS
368Pre-existing condition improvedFAERS: 1US FAERS
369Procedural complicationFAERS: 1US FAERS
370Product coating issueFAERS: 1US FAERS
371Product container issueFAERS: 1US FAERS
372Product counterfeitFAERS: 1US FAERS
373Product label issueFAERS: 1US FAERS
374Product lot number issueFAERS: 1US FAERS
375Product measured potency issueFAERS: 1US FAERS
376Product packaging issueFAERS: 1US FAERS
377Product physical issueFAERS: 1US FAERS
378Product prescribing errorFAERS: 1US FAERS
379Product residue presentFAERS: 1US FAERS
380Product shape issueFAERS: 1US FAERS
381Product size issueFAERS: 1US FAERS
382Product storage errorFAERS: 1US FAERS
383Product supply issueFAERS: 1US FAERS
384Pulmonary EmbolismFAERS: 1US FAERS
385Quality of life decreasedFAERS: 1US FAERS
386Reaction to excipientFAERS: 1US FAERS
387Renal abscessFAERS: 1US FAERS
388Renal cystFAERS: 1US FAERS
389Renal painFAERS: 1US FAERS
390Respiratory ParalysisFAERS: 1US FAERS
391Respiratory distressFAERS: 1US FAERS
392Restless Legs SyndromeFAERS: 1US FAERS
393Retinal DegenerationFAERS: 1US FAERS
394RhabdomyolysisFAERS: 1US FAERS
395Rheumatoid ArthritisFAERS: 1US FAERS
396Rotator cuff syndromeFAERS: 1US FAERS
397SarcoidosisFAERS: 1US FAERS
398ScreamingFAERS: 1US FAERS
399Sexual DysfunctionFAERS: 1US FAERS
400Shoulder PainFAERS: 1US FAERS
401Sinus headacheFAERS: 1US FAERS
402Skin lacerationFAERS: 1US FAERS
403Skin reactionFAERS: 1US FAERS
404Sleep disorder due to a general medical conditionFAERS: 1US FAERS
405Spinal column stenosisFAERS: 1US FAERS
406SunburnFAERS: 1US FAERS
407Symptom recurrenceFAERS: 1US FAERS
408Tablet issueFAERS: 1US FAERS
409Tablet physical issueFAERS: 1US FAERS
410Terminal stateFAERS: 1US FAERS
411Therapeutic agent-diagnostic test interactionFAERS: 1US FAERS
412Therapeutic product contaminationFAERS: 1US FAERS
413Therapeutic product effect decreasedFAERS: 1US FAERS
414Therapeutic product effective for unapproved indicationFAERS: 1US FAERS
415Therapeutic response changedFAERS: 1US FAERS
416Therapy cessationFAERS: 1US FAERS
417Therapy changeFAERS: 1US FAERS
418Therapy regimen changedFAERS: 1US FAERS
419Thermal burnFAERS: 1US FAERS
420ThrombocytopeniaFAERS: 1US FAERS
421ToothacheFAERS: 1US FAERS
422Transcription medication errorFAERS: 1US FAERS
423Unresponsive to stimuliFAERS: 1US FAERS
424Upper-airway cough syndromeFAERS: 1US FAERS
425Urinary IncontinenceFAERS: 1US FAERS
426Uterine spasmFAERS: 1US FAERS
427Vascular stenosisFAERS: 1US FAERS
428Vascular stent occlusionFAERS: 1US FAERS
429Venous InsufficiencyFAERS: 1US FAERS
430Visual disturbanceFAERS: 1US FAERS
431Vitreous floatersFAERS: 1US FAERS
432Vulvovaginal burning sensationFAERS: 1US FAERS
433Vulvovaginal drynessFAERS: 1US FAERS
434Vulvovaginal pruritusFAERS: 1US FAERS
435Withdrawal hypertensionFAERS: 1US FAERS
436Wrong product administeredFAERS: 1US FAERS
437heart rateFAERS: 1US FAERS
438kyphosisFAERS: 1US FAERS
439nervous system disorderFAERS: 1US FAERS
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