MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Cri-du-Chat Syndrome

(UMLS:C0010314)

Definition:: An infantile syndrome characterized by a cat-like cry, failure to thrive, microcephaly, MENTAL RETARDATION, spastic quadriparesis, micro- and retrognathia, glossoptosis, bilateral epicanthus, hypertelorism, and tiny external genitalia. It is caused by a deletion of the short arm of chromosome 5 (5p-).
UMLS ID:: C0010314
MeSH ID:: D003410

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.597.606.360.180

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.077.262|C16.131.260.190|C16.320.180.190

Synonym(s)

Cri-du-Chat Syndrome

5P minus (partial) syndrome

5p Deletion Syndrome

5p Partial Monosomy Syndrome

5p deletion syndrome

5p minus syndrome

5p partial monosomy syndrome

5p syndrome

5p- syndrome

10.

CRI-DU-CHAT SYNDROME

11.

Cat-Cry Syndrome

12.

Chromosomal imbalance syndrome, pair 5, deletion, short arm

13.

Cri Du Chat Syndrome

14.

Cri du Chat Syndrome

15.

Cri du Chat syndrome

16.

Cri du chat syndrome

17.

Cri-du-chat syndrome

18.

Crying Cat Syndrome

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	aminoacetone		11559049	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Down Syndrome	63.6%
2	Trisomy 21	63.6%
3	Beckwith-Wiedemann Syndrome	58.8%
4	Wolf-Hirschhorn Syndrome	58.8%
5	Prader-Willi Syndrome	56.4%
6	Smith-Magenis syndrome	54%
7	Rubinstein-Taybi Syndrome	52.4%
8	Holoprosencephaly	50.8%
9	Williams Syndrome	45.2%
10	Fragile X Syndrome	40.7%
11	Aicardi's syndrome	35.6%
12	CHARGE Syndrome	35.4%
13	Ectodermal Dysplasia	33.9%
14	Aplasia Cutis Congenita	33.9%
15	Nail-Patella Syndrome	31.2%
16	Prune Belly Syndrome	29.1%
17	Waardenburg Syndrome	29.1%
18	Marfan Syndrome	29%
19	Kartagener Syndrome	29%
20	Cockayne Syndrome	28.8%
21	Abnormalities, Drug-Induced	28.2%
22	Situs Inversus	28.2%
23	Alstrom Syndrome	27.8%
24	Mobius Syndrome	27.2%
25	Polycystic Kidney Diseases	26.3%
26	Anencephaly	24.5%
27	Rett Syndrome	24.5%
28	Bloom Syndrome	24.3%
29	Eye Abnormalities	24.3%
30	Cardiovascular Abnormalities	24.3%
31	Smith-Lemli-Opitz Syndrome	24.2%
32	Skin Abnormalities	23.7%
33	Lymphatic Abnormalities	23.7%
34	Congenital Microtia	23.7%
35	Congenital diaphragmatic hernia	23.3%
36	Primary Ciliary Dyskinesia	23%
37	Dural Arteriovenous Fistula	22.5%
38	Ichthyosis, X-Linked	22.2%
39	Urogenital Abnormalities	20.9%
40	Mucopolysaccharidosis II	20.9%
41	Cystic Fibrosis	20.6%
42	Maxillofacial Abnormalities	20.4%
43	Dextrocardia	20.2%
44	Turner Syndrome	20.2%
45	Klinefelter Syndrome	19.9%
46	Polycystic Kidney, Autosomal Dominant	19.5%
47	Menkes Kinky Hair Syndrome	19.5%
48	Xeroderma	19.2%
49	POEMS Syndrome	18.9%
50	Classical Lissencephalies and Subcortical Band Heterotopias	18.6%
51	Twins, Conjoined	18.5%
52	Hydranencephaly	18.4%
53	Neural Tube Defects	18.4%
54	Tethered Cord Syndrome	18.4%
55	Iniencephaly	18.4%
56	Craniorachischisis	18.4%
57	Exencephaly	18.4%
58	Septo-Optic Dysplasia	18.4%
59	Cortical Dysplasia	18.4%
60	Myasthenic Syndromes, Congenital	18.4%
61	Malformations of Cortical Development	18.4%
62	Retinal Dysplasia	18.1%
63	Aniridia	18%
64	Epidermolysis Bullosa	17.7%
65	Zellweger Syndrome	17.7%
66	Tuberous Sclerosis	17.5%
67	Fetal Diseases	17.3%
68	Neoplastic Syndromes, Hereditary	17.3%
69	Muscular Dystrophy, Duchenne	17%
70	Multiple Epiphyseal Dysplasia	16.8%
71	Osteochondrodysplasias	16.8%
72	Pelger-Huet Anomaly	16.8%
73	Werner Syndrome	16.8%
74	Albinism	16.6%
75	Microcephaly	16.6%
76	Macrocephaly	16.6%
77	Scimitar Syndrome	16.6%
78	Cri-du-Chat Syndrome	16.5%
79	Adrenoleukodystrophy	16.5%
80	Anemia, Sickle Cell	16.5%
81	Thalassemia	16.5%
82	Sjogren-Larsson Syndrome	16.5%
83	Basal Cell Nevus Syndrome	16.2%
84	Acrocephalosyndactylia	16.1%
85	Refsum Disease	16%
86	Anophthalmos	15.6%
87	Anus, Imperforate	15.6%
88	Microphthalmos	15.6%
89	Limb Deformities, Congenital	15.6%
90	Craniofacial Abnormalities	15.6%
91	Anorectal Malformations	15.6%
92	Kallmann Syndrome	15.6%
93	Abnormalities, Radiation-Induced	15.5%
94	Charcot-Marie-Tooth Disease	15.4%
95	Dandy-Walker Syndrome	15.4%
96	Craniosynostosis	15.3%
97	Syndactyly	15.3%
98	Brachycephaly	15.3%
99	Muscular Dystrophy	15.2%
100	Porencephaly	15%
101	Central Nervous System Cysts	15%
102	Dwarfism	14.8%
103	Pseudoxanthoma Elasticum	14.5%
104	Osteogenesis Imperfecta	14.3%
105	Noonan Syndrome	14%
106	Myotonic Dystrophy	13.9%
107	Genetic Diseases, Inborn	13.8%
108	Cleft Palate	13.6%
109	Meconium Aspiration Syndrome	13.6%
110	Blepharophimosis	13.5%
111	Laryngostenosis	13.5%
112	Mouth Abnormalities	13.5%
113	Hyperkeratosis, Epidermolytic	13.5%
114	Esophageal Atresia	13.4%
115	Intestinal Atresia	13.4%
116	Horseshoe Kidney	13.4%
117	Pectus excavatum	13.4%
118	Xeroderma Pigmentosum	13.4%
119	Klippel-Feil Syndrome	13.3%
120	Gastroschisis	13.3%
121	Synostosis	13.3%
122	Acrodermatitis	13.3%
123	Lymphangiectasis, Intestinal	13.3%
124	Gianotti-Crosti Syndrome	13.3%
125	Familial Mediterranean Fever	13.2%
126	Meningomyelocele	13.2%
127	Spina Bifida	13.2%
128	Wiskott-Aldrich Syndrome	13.2%
129	Antley-Bixler Syndrome Phenotype	13.1%
130	Hepatolenticular Degeneration	13%
131	Neuronal Ceroid-Lipofuscinoses	12.9%
132	Jaw Abnormalities	12.8%
133	Autoimmune Lymphoproliferative Syndrome	12.7%
134	Poland Syndrome	12.6%
135	Angioedemas, Hereditary	12.4%
136	Sickle Cell Trait	12.2%
137	Ataxia Telangiectasia	12.2%
138	Abdominal Cramps	12.1%
139	Amniotic Band Syndrome	12.1%
140	Asphyxia Neonatorum	12.1%
141	Infant, Premature, Diseases	12.1%
142	Infantile Colic	12.1%
143	Arthrogryposis	11.9%
144	Choanal Atresia	11.9%
145	Tracheobronchomegaly	11.9%
146	Laryngocele	11.9%
147	Amyloid Neuropathies, Familial	11.9%
148	Choledochal Cyst	11.8%
149	Hermaphroditism	11.8%
150	Disorders of Sex Development	11.8%
151	Cryptorchidism	11.7%
152	Hypospadias	11.7%
153	Amelia	11.5%
154	Arachnodactyly	11.5%
155	Ectopia Cordis	11.5%
156	Ectromelia	11.5%
157	Hemimelia	11.5%
158	Phocomelia	11.5%
159	Sirenomelia	11.5%
160	Polydactyly	11.5%
161	Brachydactyly	11.5%
162	Plagiocephaly	11.5%
163	Lower Extremity Deformities, Congenital	11.5%
164	Upper Extremity Deformities, Congenital	11.5%
165	Single umbilical artery	11.5%
166	Meningocele	11.3%
167	Encephalocele	11.3%
168	Fabry Disease	11.3%
169	Canavan Disease	11.2%
170	Alexander Disease	11.2%
171	Dystonia Musculorum Deformans	11.1%
172	Amino Acid Metabolism, Inborn Errors	11%
173	Carbohydrate Metabolism, Inborn Errors	11%
174	Metal Metabolism, Inborn Errors	11%
175	Progeria	11%
176	Lysosomal Storage Diseases	11%
177	Cytochrome-c Oxidase Deficiency	11%
178	Peroxisomal Disorders	11%
179	Micrognathism	10.8%
180	Pierre Robin Syndrome	10.8%
181	Dermal Sinus	10.6%
182	Spina Bifida Cystica	10.6%
183	Spina Bifida Occulta	10.6%
184	Lissencephaly	10.6%
185	Polymicrogyria	10.6%
186	Pachygyria	10.6%
187	Schizencephaly	10.6%
188	Periventricular Nodular Heterotopia	10.6%
189	Laryngomalacia	10.6%
190	Pectus carinatum	10.5%
191	Glycogen storage disease type II	10.4%
192	Bladder Exstrophy	10.4%
193	Epispadias	10.4%
194	Myotonia Congenita	10.3%
195	Lafora Disease	10.3%
196	Unverricht-Lundborg Syndrome	10.3%
197	Multicystic Dysplastic Kidney	10.3%
198	Galactosemias	10.2%
199	Urea Cycle Disorders, Inborn	10.2%
200	Tyrosinemias	10.2%
201	Welander Distal Myopathy	10.1%
202	Anemia, Neonatal	10.1%
203	Persistent Fetal Circulation Syndrome	10.1%
204	Confusion	10%
205	Lethargy	10%
206	Memory Disorders	10%
207	Perceptual Disorders	10%
208	Psychomotor Disorders	10%
209	Anhedonia	10%
210	Disorientation	10%
211	Memory Loss	10%
212	Hemisensory Neglect	10%
213	Umbilical hernia	10%
214	Optic Atrophy, Hereditary, Leber	10%
215	Acute Chest Syndrome	9.9%
216	Aortic coarctation	9.9%
217	Cor Triatriatum	9.9%
218	Coronary Vessel Anomalies	9.9%
219	Dental Enamel Hypoplasia	9.9%
220	Patent ductus arteriosus	9.9%
221	Ebstein Anomaly	9.9%
222	Heart Septal Defects	9.9%
223	Hypodontia	9.9%
224	Macrostomia	9.9%
225	Microstomia	9.9%
226	Tetralogy of Fallot	9.9%
227	Transposition of Great Vessels	9.9%
228	Hypoplastic Left Heart Syndrome	9.9%
229	May-Thurner Syndrome	9.9%
230	Retrognathia	9.9%
231	Craniofacial Dysostosis	9.9%
232	Wolff-Parkinson-White Syndrome	9.8%
233	Duane Retraction Syndrome	9.7%
234	Cutis Laxa	9.6%
235	Retinitis Pigmentosa	9.5%
236	Congenital nystagmus	9.5%
237	Pigmentary retinopathy	9.5%
238	Porokeratosis	9.5%
239	Keratoderma, Palmoplantar	9.5%
240	Chronic granulomatous disease	9.4%
241	Hyperandrogenism	9.4%
242	Toxoplasmosis, Congenital	9.2%
243	Brain Diseases, Metabolic, Inborn	9.1%
244	Prognathism	9.1%
245	Mucopolysaccharidosis III	9%
246	Hyperphosphaturia	8.9%
247	Consciousness Disorders	8.8%
248	Depressed Level of Consciousness	8.8%
249	Neonatal Abstinence Syndrome	8.8%
250	Catatonia	8.7%
251	Long QT Syndrome	8.7%
252	Platybasia	8.7%
253	Tricuspid Atresia	8.7%
254	Arrhythmogenic Right Ventricular Dysplasia	8.7%
255	Gonadal Dysgenesis	8.6%
256	Bronchomalacia	8.6%
257	Adrenogenital Syndrome	8.6%
258	Tracheomalacia	8.6%
259	Ovotesticular Disorders of Sex Development	8.6%
260	Homocystinuria	8.6%
261	Fetal Growth Retardation	8.6%
262	Asterixis	8.6%
263	Ballismus	8.6%
264	Gaucher Disease	8.6%
265	Fetal Hypoxia	8.6%
266	Fetal Alcohol Spectrum Disorders	8.6%
267	Leigh Disease	8.6%
268	Huntington Disease	8.5%
269	Syphilis, Congenital	8.5%
270	Decerebrate State	8.4%
271	Hemiparesis	8.4%
272	Meningism	8.4%
273	Paresis	8.4%
274	Seizures	8.4%
275	Sensation Disorders	8.4%
276	Complex partial seizures	8.4%
277	Monoparesis	8.4%
278	Neurogenic Inflammation	8.4%
279	Gait Disorders, Neurologic	8.4%
280	Neuromuscular Manifestations	8.4%
281	Akathisia	8.4%
282	Restlessness	8.4%
283	Psychomotor Agitation	8.4%
284	Porphyrias, Hepatic	8.4%
285	Peutz-Jeghers Syndrome	8.3%
286	Thrombasthenia	8.3%
287	Antithrombin III Deficiency	8.3%
288	Protein C Deficiency	8.3%
289	Afibrinogenemia	8.2%
290	Factor VII Deficiency	8.2%
291	Factor X Deficiency	8.2%
292	Factor XII Deficiency	8.2%
293	Hemophilia A	8.2%
294	Activated Protein C Resistance	8.2%
295	Factor II deficiency	8.2%
296	Factor VIII Deficiency	8.2%
297	Factor V deficiency	8.2%
298	Factor XI Deficiency	8.2%
299	Hypoprothrombinemias	8.2%
300	Alkaptonuria	8.2%
301	Fanconi Anemia	8.2%
302	Glycogen Storage Disease	8.2%
303	Hypophosphatasia	8.2%
304	Propionic acidemia	8.2%
305	Dihydropyrimidine Dehydrogenase Deficiency	8.2%
306	Cystinosis	8.2%
307	Anemia, Diamond-Blackfan	8.2%
308	Aortopulmonary Septal Defect	8.2%
309	Double Outlet Right Ventricle	8.2%
310	Endocardial Cushion Defects	8.2%
311	Myocardial bridging	8.2%
312	Aorticopulmonary Septal Defect	8.2%
313	Tay-Sachs Disease	7.8%
314	Carbamoyl-Phosphate Synthase I Deficiency Disease	7.7%
315	Language Disorders	7.6%
316	Alexia	7.6%
317	Dyslexia	7.6%
318	Multiple Endocrine Neoplasia	7.5%
319	Congenital Hyperinsulinism	7.5%
320	Chorioamnionitis	7.5%
321	Niemann-Pick Disease, Type C	7.5%
322	Familial Periodic Paralysis	7.5%
323	Friedreich Ataxia	7.4%
324	Congenital Hypothyroidism	7.4%
325	Pupil Disorders	7.4%
326	Dermatitis, Atopic	7.4%
327	Hydrops Fetalis	7.4%
328	Truncus Arteriosus, Persistent	7.3%
329	Goldenhar Syndrome	7.3%
330	Vertigo	7.1%
331	Mandibulofacial Dysostosis	7.1%
332	Romano-Ward Syndrome	7.1%
333	Gait Apraxia	7.1%
334	Hypolipoproteinemias	7%
335	Papillon-Lefevre Disease	7%
336	Hyperlipidemia, Familial Combined	7%
337	Hyperlipoproteinemia Type III	7%
338	Alice in Wonderland Syndrome	6.9%
339	Deformity	6.9%
340	Glycogen Storage Disease Type I	6.8%
341	Glycogen Storage Disease Type V	6.8%
342	Paralysis, Obstetric	6.7%
343	Retinopathy of Prematurity	6.7%
344	Behcet Syndrome	6.6%
345	Bronchopulmonary Dysplasia	6.6%
346	Leukomalacia, Periventricular	6.6%
347	Agnosia	6.6%
348	Apraxias	6.6%
349	Hallucinations	6.6%
350	Visual Agnosia	6.6%
351	Anosognosia	6.6%
352	Wernicke-Korsakoff Syndrome	6.6%
353	Denys-Drash Syndrome	6.5%
354	Talipes	6.4%
355	Voice Disorders	6.4%
356	Voice Disturbance	6.4%
357	Cranial nerve diseases	6.2%
358	Demyelinating Diseases	6.2%
359	Demyelination	6.2%
360	Neuromuscular Diseases	6.2%
361	Chronobiology Disorders	6.2%
362	Lactose Intolerance	6.1%
363	Variegate Porphyria	6.1%
364	Acute intermittent porphyria	6.1%
365	Porphyria Cutanea Tarda	6.1%
366	Gait Ataxia	6.1%
367	Hyperhomocysteinemia	6.1%
368	Renal Aminoacidurias	6.1%
369	Fanconi Syndrome	6.1%
370	Pseudohypoaldosteronism	6.1%
371	Liddle Syndrome	6.1%
372	Hyperlipoproteinemia Type IV	6.1%
373	Hyperlipoproteinemia Type V	6.1%
374	Congenital clubfoot	6%
375	Vertical Talus	6%
376	Hypokalemic periodic paralysis	5.9%
377	Ophthalmia Neonatorum	5.9%
378	Persistent Vegetative State	5.8%
379	Hypoalphalipoproteinemias	5.8%
380	Amnesia	5.8%
381	Delirium	5.8%
382	Respiratory Distress Syndrome, Newborn	5.8%
383	Dissociative Amnesia	5.8%
384	Global Amnesia	5.8%
385	Ophthalmoplegic Migraine	5.8%
386	Arteriovenous fistula	5.7%
387	Agraphia	5.7%
388	Anomia	5.7%
389	Cluttering	5.7%
390	Language Development Disorders	5.7%
391	Speech Disorders	5.7%
392	Syncope	5.7%
393	Stupor	5.7%
394	Dysgraphia	5.7%
395	Presyncope	5.7%
396	Dyslalia	5.7%
397	Motor Neuron Disease	5.6%
398	Gout	5.5%
399	Brain Death	5.5%
400	Coma, Post-Head Injury	5.5%
401	Reflex, Abnormal	5.5%
402	Hyporeflexia	5.5%
403	Hyperreflexia	5.5%
404	Multiple Endocrine Neoplasia Type 1	5.5%
405	Pseudohypoparathyroidism	5.5%
406	Stiff-Person Syndrome	5.5%
407	Nephroblastoma	5.5%
408	Renal tubular acidosis	5.4%
409	Multiple System Atrophy	5.4%
410	Dyskinesia, Drug-Induced	5.4%
411	Trauma, Nervous System	5.3%
412	Restless Legs Syndrome	5.2%
413	Auditory Perceptual Disorders	5.2%
414	Nervous System Neoplasms	5.2%
415	Neurotoxicity Syndromes	5.2%
416	Chorea	5.2%
417	Phantom pain	5.1%
418	Phantom Limb Pain	5.1%
419	Cystinuria	5.1%
420	Polyradiculoneuropathy	5%
421	Polyradiculoneuritis	5%
422	Adenomatous Polyposis Coli	5%
423	Familial Hypophosphatemic Rickets	5%
424	Ophthalmoplegia	5%
425	External Ophthalmoplegia	5%
426	Ocular Motility Disorders	5%
427	Cyclophoria	5%
428	Anosmia	4.9%
429	Ataxia	4.9%
430	Athetosis	4.9%
431	Catalepsy	4.9%
432	Dystonia	4.9%
433	Hemiplegia	4.9%
434	Locked-In Syndrome	4.9%
435	Muscle Hypertonia	4.9%
436	Muscle hypotonia	4.9%
437	Myoclonus	4.9%
438	Myotonia	4.9%
439	Paraplegia	4.9%
440	Pseudobulbar Palsy	4.9%
441	Quadriplegia	4.9%
442	Spasm	4.9%
443	Spastic Paraplegia	4.9%
444	Status Epilepticus	4.9%
445	Taste Disorders	4.9%
446	Tremor	4.9%
447	Monoplegia	4.9%
448	Hypokinesia	4.9%
449	Paraparesis	4.9%
450	Bradykinesia	4.9%
451	Waxy flexibility	4.9%
452	Action Tremor	4.9%
453	Resting Tremor	4.9%
454	Dysosmia	4.9%
455	Quadriparesis	4.9%
456	Olfaction Disorders	4.9%
457	Myokymia	4.9%
458	Somatosensory Disorders	4.9%
459	Hyperkinesia	4.9%
460	Intention tremor	4.9%
461	Nesidioblastosis	4.9%
462	Amnesia, Transient Global	4.9%
463	Dyscalculia	4.9%
464	Gerstmann Syndrome	4.9%
465	Prosopagnosia	4.9%
466	Apraxia, Ideomotor	4.9%
467	Charles Bonnet Syndrome	4.9%
468	Alien Hand Syndrome	4.9%
469	MELAS Syndrome	4.9%
470	Subacute Combined Degeneration	4.8%
471	Progressive supranuclear palsy	4.8%
472	Aphasia	4.7%
473	Articulation Disorders	4.7%
474	Echolalia	4.7%
475	Stuttering	4.7%
476	Dysphasia	4.7%
477	Kernicterus	4.7%
478	Horner Syndrome	4.6%
479	Opsoclonus-Myoclonus Syndrome	4.5%
480	Arthritis, Gouty	4.5%
481	Sleep Wake Disorders	4.5%
482	Cerebrospinal Fluid Otorrhea	4.5%
483	Cerebrospinal Fluid Rhinorrhea	4.5%
484	Vocal Cord Paralysis	4.5%
485	Encephalomyelitis	4.5%
486	Prion Diseases	4.5%
487	Autonomic Dysreflexia	4.5%
488	Complex Regional Pain Syndromes	4.5%
489	Glycosuria, Renal	4.4%
490	Amyotrophic Lateral Sclerosis	4.4%
491	Vision Disorders	4.4%
492	Metamorphopsia	4.4%
493	Visual Impairment	4.4%
494	Anisocoria	4.3%
495	Facial paralysis	4.3%
496	Muscle Cramp	4.3%
497	Tonic Pupil	4.3%
498	Facial Paresis	4.3%
499	Dysacusis	4.3%
500	Retrograde amnesia	4.3%
501	Amnesia, Anterograde	4.3%
502	Spinal Muscular Atrophy	4.3%
503	Progressive Muscular Atrophy	4.3%
504	Dysarthria	4.3%
505	Hyaline Membrane Disease	4.2%
506	Muscular Atrophy	4.2%
507	Respiratory Paralysis	4.2%
508	Tetany	4.2%
509	Meningoencephalitis	4.1%
510	Mutism	4.1%
511	Selective Mutism	4.1%
512	Parkinson Disease	4%
513	Spinal Cord Injuries	3.9%
514	Alcohol Withdrawal Seizures	3.9%
515	Marchiafava-Bignami Disease	3.9%
516	Peripheral Nerve Injuries	3.9%
517	Lewy Body Disease	3.9%
518	Guillain-Barre Syndrome	3.8%
519	Myasthenia Gravis	3.8%
520	Muscle Weakness	3.8%
521	Cerebellar Ataxia	3.7%
522	Torticollis	3.7%
523	Amblyopia	3.7%
524	Aphonia	3.7%
525	Pneumocephalus	3.7%
526	Poliomyelitis	3.7%
527	Dysphonia	3.7%
528	Lambert-Eaton Myasthenic Syndrome	3.7%
529	Alexia, Pure	3.7%
530	Myelitis, Transverse	3.6%
531	Tardive Dyskinesia	3.5%
532	Striatonigral Degeneration	3.5%
533	Chronic Fatigue Syndrome	3.5%
534	Leukoencephalitis, Acute Hemorrhagic	3.5%
535	Sleep Disorders, Circadian Rhythm	3.4%
536	Brain Diseases	3.4%
537	Dysautonomia	3.4%
538	Meningitis	3.4%
539	Movement Disorders	3.4%
540	Pachymeningitis	3.4%
541	Spinal Cord Diseases	3.4%
542	Vagus Nerve Disorder	3.4%
543	Glossopharyngeal Neuralgia	3.4%
544	Abducens Nerve Diseases	3.4%
545	Heavy Metal Poisoning, Nervous System	3.4%
546	Neuromuscular Junction Diseases	3.4%
547	Tauopathies	3.4%
548	Trochlear Nerve Diseases	3.4%
549	Peripheral Nervous System Diseases	3.4%
550	Miller Fisher Syndrome	3.3%
551	Botulism	3.3%
552	Neuroleptic Malignant Syndrome	3.3%
553	Myelinolysis, Central Pontine	3.3%
554	Myelitis	3.3%
555	Progressive bulbar palsy	3.3%
556	Bulbar palsy	3.3%
557	Epidural Abscess	3.3%
558	Olfactory Nerve Injuries	3.3%
559	Causalgia	3.3%
560	Neuromyelitis Optica	3.3%
561	Dysgeusia	3.3%
562	Formication	3.3%
563	Hyperalgesia	3.3%
564	Hyperesthesia	3.3%
565	Hypesthesia	3.3%
566	Numbness	3.3%
567	Paresthesia	3.3%
568	Paraparesis, Spastic	3.3%
569	Trismus	3.3%
570	Epilepsia Partialis Continua	3.3%
571	Hypogeusia	3.3%
572	Brown-Sequard Syndrome	3.3%
573	Lockjaw	3.3%
574	Allodynia	3.3%
575	Ageusia	3.3%
576	MPTP Poisoning	3.2%
577	Shy-Drager Syndrome	3.1%
578	Encephalomyelitis, Acute Disseminated	3.1%
579	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	3.1%
580	Hoarseness	3%
581	Akathisia, Drug-Induced	3%
582	Facial Nerve Injuries	2.9%
583	Central Nervous System Infection	2.9%
584	Myopathy	2.9%
585	Optic Neuropathy	2.9%
586	Leukoencephalopathy, Progressive Multifocal	2.9%
587	Brain Injuries	2.8%
588	Diplopia	2.8%
589	Muscle Rigidity	2.8%
590	Muscle Spasticity	2.8%
591	Scotoma	2.8%
592	Photophobia	2.8%
593	Cogwheel Rigidity	2.8%
594	Hemifacial Spasm	2.8%
595	Amaurosis	2.8%
596	Blindness	2.8%
597	Nuchal Rigidity	2.8%
598	Brain Neoplasms	2.8%
599	Multiple Sclerosis	2.8%
600	Spinal Cord Neoplasms	2.8%
601	Facial Nerve Diseases	2.8%
602	Craniocerebral Trauma	2.8%
603	Parasomnia	2.8%
604	Dyssomnias	2.8%
605	Hemianopsia	2.8%
606	Hyperacusis	2.8%
607	Tinnitus	2.8%
608	Phonophobia	2.8%
609	Hearing Loss	2.8%
610	Sarcopenia	2.8%
611	Vestibulocochlear Nerve Diseases	2.8%
612	Central Nervous System Neoplasms	2.8%
613	Sweating, Gustatory	2.8%
614	Auriculotemporal Syndrome	2.8%
615	Reflex Sympathetic Dystrophy	2.7%
616	Subdural Effusion	2.7%
617	Parkinsonian Disorders	2.7%
618	Nocturnal Myoclonus Syndrome	2.7%
619	Myasthenia Gravis, Autoimmune, Experimental	2.6%
620	Vasculitis, Central Nervous System	2.6%
621	Jet Lag Syndrome	2.6%
622	Limbic Encephalitis	2.6%
623	Brain Abscess	2.5%
624	Lupus Vasculitis, Central Nervous System	2.5%
625	Color blindness	2.5%
626	Epilepsy, Post-Traumatic	2.4%
627	Paraneoplastic Encephalomyelitis	2.4%
628	Uveomeningoencephalitic Syndrome	2.4%
629	Scrapie	2.4%
630	Sturge-Weber Syndrome	2.4%
631	Central Cord Syndrome	2.4%
632	Alcohol-Induced Disorders, Nervous System	2.4%
633	Presenile dementia	2.4%
634	Senile dementia	2.4%
635	Meningitis, Bacterial	2.4%
636	Meningitis, Fungal	2.4%
637	Acrodynia	2.3%
638	Meige Syndrome	2.2%
639	Brachial Plexus Neuritis	2.2%
640	Neuralgic Amyotrophy	2.2%
641	Cerebral Ventriculitis	2.2%
642	Dementia, Vascular	2.1%
643	Brain Hemorrhage, Traumatic	2.1%
644	Amaurosis Fugax	2.1%
645	Blindness, Cortical	2.1%
646	Deafness	2.1%
647	Hearing Loss, Sudden	2.1%
648	Hearing Loss, Bilateral	2.1%
649	Hearing Loss, High-Frequency	2.1%
650	Hearing Loss, Mixed Conductive-Sensorineural	2.1%
651	Hearing Loss, Unilateral	2.1%
652	Complete Hearing Loss	2.1%
653	Deaf Mutism	2.1%
654	Paraneoplastic Cerebellar Degeneration	2.1%
655	Neuritis, Autoimmune, Experimental	2%
656	Cerebellar Neoplasms	2%
657	Akinetic Mutism	2%
658	Anoxic Encephalopathy	2%
659	Arachnoiditis	2%
660	Basal Ganglia Diseases	2%
661	Brain Damage, Chronic	2%
662	Cerebellar Diseases	2%
663	Encephalitis	2%
664	Encephalomalacia	2%
665	Epilepsy	2%
666	Hydrocephalus	2%
667	Congenital Hydrocephalus	2%
668	Hypothalamic Diseases	2%
669	Aseptic Meningitis	2%
670	Neuritis	2%
671	Polyneuritis	2%
672	Radiculitis	2%
673	Syringomyelia	2%
674	Thalamic Diseases	2%
675	Intracranial Hypertension	2%
676	Polyneuropathy	2%
677	Mononeuritis	2%
678	Aura	2%
679	Leukoencephalopathy	2%
680	Essential Tremor	2%
681	Neuroaxonal Dystrophies	2%
682	Familial Tremor	2%
683	Headache Disorders	2%
684	Mononeuropathies	2%
685	Intracranial Hypotension	2%
686	Brachial Plexus Neuropathies	2%
687	Radiculopathy	2%
688	Mononeuropathy Multiplex	2%
689	Nerve Root Compression	2%
690	Brain Edema	2%
691	Brain Hypoxia	2%
692	Aqueductal Stenosis	2%
693	Pneumorrhachis	2%
694	Writer's Cramp	2%
695	Carotid Artery Injuries	2%
696	Tarsal Tunnel Syndrome	1.9%
697	Cauda Equina Syndrome	1.9%
698	Posterior Leukoencephalopathy Syndrome	1.9%
699	Posterior reversible encephalopathy syndrome	1.9%
700	Creutzfeldt-Jakob disease	1.9%
701	Basal Ganglia Cerebrovascular Disease	1.9%
702	Brain Injuries, Diffuse	1.9%
703	Traumatic Brain Injury	1.9%
704	Supratentorial Neoplasms	1.9%
705	Multiple Sclerosis, Chronic Progressive	1.9%
706	Multiple Sclerosis, Relapsing-Remitting	1.9%
707	Tuberculosis, Meningeal	1.8%
708	Kearns-Sayre syndrome	1.7%
709	Optic Nerve Glioma	1.7%
710	Brain Diseases, Metabolic	1.7%
711	Cerebrovascular Disorders	1.7%
712	Myositis	1.7%
713	Optic Atrophy	1.7%
714	Optic Neuritis	1.7%
715	Papilledema	1.7%
716	Strabismus	1.7%
717	Tolosa-Hunt Syndrome	1.7%
718	Cerebrovascular Insufficiency	1.7%
719	Isaacs syndrome	1.7%
720	Arsenic Poisoning	1.7%
721	Dementia	1.7%
722	Myotonic Disorders	1.7%
723	Central Nervous System Fungal Infections	1.7%
724	Conus Medullaris Syndrome	1.7%
725	Spinal Cord Vascular Diseases	1.7%
726	Diabetic Neuropathies	1.7%
727	Facial Injuries	1.7%
728	Facial Neuralgia	1.7%
729	Diabetic Amyotrophy	1.7%
730	Diabetic Autonomic Neuropathy	1.7%
731	Sleep Talking	1.7%
732	Manganese Poisoning	1.7%
733	Sleep Disorders, Intrinsic	1.7%
734	Orthostatic intolerance	1.7%
735	Meningeal Neoplasms	1.6%
736	Neuralgia	1.6%
737	Mercury Poisoning, Nervous System	1.6%
738	Lead Poisoning, Nervous System	1.6%
739	Vestibular Neuronitis	1.6%
740	Neuropathic pain	1.6%
741	Carpal Tunnel Syndrome	1.6%
742	Vascular Headaches	1.6%
743	Vertebral Artery Dissection	1.6%
744	Toxoplasmosis, Cerebral	1.6%
745	neurofibroma	1.6%
746	Hypoxia-Ischemia, Brain	1.6%
747	Myoclonic Epilepsy	1.6%
748	Epilepsy, Temporal Lobe	1.6%
749	Epilepsy, Rolandic	1.6%
750	Benign Rolandic Epilepsy	1.6%
751	Sciatica	1.6%
752	Brain Concussion	1.6%
753	Acoustic Neuroma	1.5%
754	Pituitary Adenoma	1.5%
755	Pituitary Neoplasms	1.5%
756	Hand-Arm Vibration Syndrome	1.5%
757	Mitochondrial Encephalomyopathies	1.5%
758	Fibromyalgia	1.4%
759	Optic Neuropathy, Ischemic	1.4%
760	Anterior Ischemic Optic Neuropathy	1.4%
761	Central Nervous System Bacterial Infections	1.4%
762	Medial Tibial Stress Syndrome	1.4%
763	Facial Hemiatrophy	1.4%
764	Melkersson-Rosenthal Syndrome	1.4%
765	Mitochondrial Myopathies	1.4%
766	Meningitis, Cryptococcal	1.4%
767	Eosinophilia-Myalgia Syndrome	1.4%
768	Meningitis, Listeria	1.4%
769	Meningitis, Haemophilus	1.4%
770	Meningitis, Pneumococcal	1.4%
771	Frontotemporal dementia	1.4%
772	Sleep Bruxism	1.4%
773	Cubital Tunnel Syndrome	1.4%
774	Diffuse Axonal Injury	1.4%
775	Brain Stem Neoplasms	1.4%
776	Basal Ganglia Hemorrhage	1.4%
777	Juvenile Myoclonic Epilepsy	1.4%
778	Myoclonic Epilepsies, Progressive	1.4%
779	Giant Cell Arteritis	1.3%
780	Temporal Arteritis	1.3%
781	Subarachnoid Hemorrhage, Traumatic	1.3%
782	Carotid Artery, Internal, Dissection	1.3%
783	Cerebral Palsy	1.3%
784	Epilepsies, Partial	1.3%
785	Epilepsy, Generalized	1.3%
786	Pseudotumor Cerebri	1.3%
787	Sciatic Neuropathy	1.3%
788	Hypertensive Encephalopathy	1.3%
789	Ulnar Neuropathies	1.3%
790	Lesion of Sciatic Nerve	1.3%
791	Simple Partial Seizures	1.3%
792	Epilepsy, Reflex	1.3%
793	Ulnar Neuritis	1.3%
794	Radial nerve compression	1.3%
795	Radial Tunnel Syndrome	1.3%
796	Peroneal Neuropathies	1.3%
797	Radial Neuropathy	1.3%
798	Median Neuropathy	1.3%
799	Sciatic Nerve Palsy	1.3%
800	Femoral Neuropathy	1.3%
801	Tibial Neuropathy	1.3%
802	Ulnar Nerve Palsy	1.3%
803	Postural Orthostatic Tachycardia Syndrome	1.3%
804	Radial nerve palsy	1.3%
805	Headache Disorders, Primary	1.3%
806	Headache Disorders, Secondary	1.3%
807	Medication overuse headache	1.3%
808	Subacute Sclerosing Panencephalitis	1.3%
809	Bell Palsy	1.3%
810	Herpes Zoster Oticus	1.2%
811	Sleep Deprivation	1.2%
812	Pituitary Apoplexy	1.2%
813	Brain Contusion	1.2%
814	Brain Infarction	1.2%
815	Putaminal Hemorrhage	1.2%
816	Choroid Plexus Papilloma	1.2%
817	Pituitary Diseases	1.1%
818	Infarction, Middle Cerebral Artery	1.1%
819	Infarction, Anterior Cerebral Artery	1.1%
820	Infarction, Posterior Cerebral Artery	1.1%
821	Thoracic Outlet Syndrome	1.1%
822	Myalgia	1.1%
823	Carotid Artery Diseases	1.1%
824	Brain Ischemia	1.1%
825	Esotropia	1.1%
826	Exotropia	1.1%
827	Hypotension, Orthostatic	1.1%
828	Sleep Apnea Syndromes	1.1%
829	Cerebrovascular accident	1.1%
830	Polymyositis	1.1%
831	Kluver-Bucy Syndrome	1.1%
832	Vasospasm, Intracranial	1.1%
833	Spinal Cord Ischemia	1.1%
834	Intracranial Arterial Diseases	1.1%
835	Post-Exercise Hypotension	1.1%
836	Disorders of Excessive Somnolence	1.1%
837	Sleep Initiation and Maintenance Disorders	1.1%
838	Night Terrors	1.1%
839	Somnambulism	1.1%
840	Trigeminal Nerve Disorder	1.1%
841	Transient Insomnia	1.1%
842	Sleep Paralysis	1.1%
843	Chronic Insomnia	1.1%
844	REM Sleep Behavior Disorder	1.1%
845	Hypersomnia	1.1%
846	Meningeal Carcinomatosis	1.1%
847	Lead Poisoning, Nervous System, Childhood	1.1%
848	Lead Poisoning, Nervous System, Adult	1.1%
849	Tuberculosis, Central Nervous System	1.1%
850	Hematoma, Subdural	1.1%
851	Hematoma, Epidural, Cranial	1.1%
852	Cerebral Infarction	1%
853	Brain Stem Infarctions	1%
854	Moyamoya Disease	1%
855	Alcohol Withdrawal Delirium	1%
856	Neurofibrosarcoma	1%
857	West Nile Fever	1%
858	Polyradiculopathy	1%
859	Post-Traumatic Headache	1%
860	Tension Headache	1%
861	Epilepsy, Complex Partial	1%
862	Migraine Disorders	1%
863	Abdominal Migraine	1%
864	Status Migrainosus	1%
865	Cervicogenic Headache	1%
866	Eye Injuries	1%
867	Orbital Myositis	1%
868	Reye Syndrome	0.9%
869	Neuroaspergillosis	0.9%
870	Pyomyositis	0.9%
871	Intracranial Embolism and Thrombosis	0.9%
872	Hepatic Encephalopathy	0.9%
873	Lateral Medullary Syndrome	0.9%
874	Pseudorabies	0.9%
875	Hematoma, Subdural, Intracranial	0.8%
876	Hematoma, Subdural, Chronic	0.8%
877	Hematoma, Subdural, Acute	0.8%
878	Empty Sella Syndrome	0.8%
879	Hyperpituitarism	0.8%
880	Hypopituitarism	0.8%
881	Hypophysitis	0.8%
882	Meningioma	0.8%
883	Cluster Headache	0.8%
884	Migraine with Aura	0.8%
885	Familial Hemiplegic Migraine	0.8%
886	Chronic Paroxysmal Hemicrania	0.8%
887	SUNCT Syndrome	0.8%
888	Paroxysmal Hemicrania	0.8%
889	Cerebral Arterial Diseases	0.8%
890	Vertebrobasilar Insufficiency	0.8%
891	Anterior Spinal Artery Syndrome	0.8%
892	Basilar Artery Stenosis	0.8%
893	Vertebral Artery Stenosis	0.8%
894	Sleep Apnea, Obstructive	0.8%
895	Sleep Apnea, Central	0.8%
896	Intracranial Hemorrhage, Hypertensive	0.8%
897	Transient Cerebral Ischemia	0.8%
898	Neurosyphilis	0.8%
899	Narcolepsy	0.8%
900	Trigeminal Neuralgia	0.8%
901	Kleine-Levin Syndrome	0.8%
902	Wernicke Encephalopathy	0.7%
903	AIDS Dementia Complex	0.7%
904	Lyme Neuroborreliosis	0.7%
905	Eye Burns	0.7%
906	Malaria, Cerebral	0.7%
907	Carotid Stenosis	0.7%
908	Intracranial Aneurysm	0.7%
909	Neurocysticercosis	0.7%
910	Intracranial Arteriosclerosis	0.7%
911	Cerebral Atherosclerosis	0.7%
912	Subarachnoid Hemorrhage	0.7%
913	Cerebral Arteriosclerosis	0.7%
914	Cerebral Hemorrhage	0.7%
915	Cerebral Thrombosis	0.7%
916	Intracranial Embolism	0.7%
917	Intracranial Thrombosis	0.7%
918	Waterhouse-Friderichsen Syndrome	0.7%
919	Hyperprolactinemia	0.7%
920	Subclavian Steal Syndrome	0.7%
921	Pick Disease of the Brain	0.7%
922	Cataplexy	0.7%
923	Dermatomyositis	0.6%
924	Corneal Scar	0.6%
925	Carotid Artery Thrombosis	0.6%
926	Acromegaly	0.6%
927	Cerebral Amyloid Angiopathy	0.6%
928	Sinus Thrombosis, Intracranial	0.6%
929	Cavernous Sinus Thrombosis	0.5%
930	Sagittal Sinus Thrombosis	0.5%
931	Corneal Perforation	0.5%
932	Nelson Syndrome	0.5%
933	Prolactinoma	0.5%
934	Growth Hormone-Secreting Pituitary Adenoma	0.5%

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