MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Angioedemas, Hereditary

(UMLS:C0019243)

Definition:: Inherited disorders that are characterized by subcutaneous and submucosal EDEMA in the upper RESPIRATORY TRACT and GASTROINTESTINAL TRACT.
UMLS ID:: C0019243
MeSH ID:: D054179

Classification 1:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.079.500

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.320.078

Classification 3:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.862.945.066.500

Classification 4:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.543.480.904.066.500

Synonym(s)

Angioedemas, Hereditary

ANGIOEDEMA, HEREDITARY

Bannister; hereditary

C-1 esterase inhibitor deficiency

C-1 esterase inhibitor deficiency syndrome

C1 esterase inhibitor deficiency

C1 esterase inhibitor; deficiency

C1 inhibitor deficiency

C1 inhibitor deficiency ('hereditary angioedema')

10.

HAE - Hereditary angio-edema

11.

HAE - Hereditary angio-oedema

12.

HAE - Hereditary angioedema

13.

HANE - Hereditary angioneurotic edema

14.

HANE - Hereditary angioneurotic oedema

15.

HEREDITARY ANGIOEDEMA

16.

Hereditary Angioedema

17.

Hereditary Quincke's edema

18.

Hereditary Quincke's oedema

19.

Hereditary angio-edema

20.

Hereditary angio-oedema

21.

Hereditary angioedema

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Danazol	View details 434701 2358093 3941465 7425772 9538488 19477491	CTD
2	Progesterone	9538488 19477491	CTD
3	Stanozolol	17765757	CTD
4	Tranexamic Acid	19477491	CTD
5	ecallantide	View details 17559913 23406939 23634741 23662043 23844784 23866957 23878046	CTD
6	icatibant	View details 23249729 23634741 23662043 23866957	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Dermatitis, Atopic	21.4%
2	Ichthyosis, X-Linked	19.8%
3	Malignant Atrophic Papulosis	19.7%
4	Albinism	19%
5	Fragile X Syndrome	18.1%
6	Behcet Syndrome	17.2%
7	Epidermolysis Bullosa	17.2%
8	Pseudoxanthoma Elasticum	16.8%
9	Polyarteritis Nodosa	16.7%
10	Takayasu Arteritis	16.7%
11	Ectodermal Dysplasia	16.6%
12	Aplasia Cutis Congenita	16.6%
13	Aicardi's syndrome	16.4%
14	Nail-Patella Syndrome	15.8%
15	Mucopolysaccharidosis II	15.7%
16	Menkes Kinky Hair Syndrome	15.7%
17	Porokeratosis	15.6%
18	Keratoderma, Palmoplantar	15.6%
19	Pyoderma Gangrenosum	15.4%
20	Xeroderma Pigmentosum	15%
21	Anemia, Sickle Cell	14.8%
22	Thalassemia	14.8%
23	Sjogren-Larsson Syndrome	14.8%
24	Muscular Dystrophy, Duchenne	14.8%
25	Alstrom Syndrome	14.6%
26	Marfan Syndrome	14.5%
27	Cutis Laxa	14.4%
28	CHARGE Syndrome	14.4%
29	Beckwith-Wiedemann Syndrome	14.2%
30	Wolf-Hirschhorn Syndrome	14.2%
31	Mucocutaneous Lymph Node Syndrome	14.1%
32	Kounis Syndrome	14.1%
33	Rett Syndrome	14%
34	Livedo Reticularis	14%
35	Cockayne Syndrome	13.9%
36	Neoplastic Syndromes, Hereditary	13.9%
37	Cystic Fibrosis	13.7%
38	Giant Cell Arteritis	13.7%
39	Temporal Arteritis	13.7%
40	Myocardial Ischemia	13.6%
41	Kartagener Syndrome	13.5%
42	Multiple Epiphyseal Dysplasia	13.4%
43	Osteochondrodysplasias	13.4%
44	Pelger-Huet Anomaly	13.4%
45	Werner Syndrome	13.4%
46	Myasthenic Syndromes, Congenital	13.4%
47	Aortic Aneurysm	13.3%
48	Aortitis	13.3%
49	Leriche Syndrome	13.3%
50	Periphlebitis	13.3%
51	Phlebitis	13.3%
52	Thromboangiitis Obliterans	13.3%
53	Autoimmune Lymphoproliferative Syndrome	13.1%
54	Fabry Disease	13.1%
55	Wiskott-Aldrich Syndrome	12.7%
56	Osteogenesis Imperfecta	12.6%
57	Smith-Magenis syndrome	12.6%
58	Cri-du-Chat Syndrome	12.4%
59	Down Syndrome	12.4%
60	Trisomy 21	12.4%
61	Ataxia Telangiectasia	12.3%
62	Retinal Vein Occlusion	12.2%
63	Sickle Cell Trait	12.2%
64	Skin Abnormalities	12.1%
65	Xeroderma	12.1%
66	Aneurysm	12.1%
67	Angiomatosis	12.1%
68	Aortic Diseases	12.1%
69	Arterial Occlusive Diseases	12.1%
70	Hyperemia	12.1%
71	Hypotension	12.1%
72	Superior Vena Cava Syndrome	12.1%
73	Telangiectasis	12.1%
74	Vasculitis	12.1%
75	Venous Insufficiency	12.1%
76	Peripheral Vascular Diseases	12.1%
77	Embolism and Thrombosis	12.1%
78	Angiodysplasia	12.1%
79	Capillary Leak Syndrome	12.1%
80	Prehypertension	12.1%
81	Holoprosencephaly	12%
82	Familial Mediterranean Fever	11.9%
83	Thrombophlebitis	11.9%
84	Adrenoleukodystrophy	11.9%
85	Dwarfism	11.8%
86	Myocardial Reperfusion Injury	11.8%
87	Smith-Lemli-Opitz Syndrome	11.8%
88	anaphylaxis	11.6%
89	Food Allergy	11.6%
90	Anaphylactic shock	11.6%
91	Postphlebitic Syndrome	11.5%
92	Neuronal Ceroid-Lipofuscinoses	11.5%
93	Muscular Dystrophy	11.4%
94	Hyperkeratosis, Epidermolytic	11.3%
95	Shwartzman Phenomenon	11.3%
96	Arteriovenous fistula	11.3%
97	Coronary Aneurysm	11.3%
98	Papillon-Lefevre Disease	11.2%
99	Aortic Rupture	11.2%
100	Scimitar Syndrome	11.1%
101	Prader-Willi Syndrome	11%
102	Williams Syndrome	10.9%
103	Glycogen storage disease type II	10.9%
104	Refsum Disease	10.8%
105	Vasculitis, Leukocytoclastic, Cutaneous	10.8%
106	Myotonic Dystrophy	10.8%
107	Porphyrias, Hepatic	10.7%
108	Hepatolenticular Degeneration	10.5%
109	Tuberous Sclerosis	10.5%
110	Rubinstein-Taybi Syndrome	10.5%
111	Vascular System Injuries	10.4%
112	Cardiovascular Abnormalities	10.4%
113	Carotid Artery Thrombosis	10.4%
114	Moyamoya Disease	10.3%
115	Blue Toe Syndrome	10.3%
116	Mucopolysaccharidosis III	10.3%
117	Compartment syndromes	10.2%
118	Hepatic Veno-Occlusive Disease	10.2%
119	Lupus Erythematosus, Cutaneous	10.2%
120	Panniculitis	10.2%
121	Peliosis Hepatis	10.2%
122	Systemic Scleroderma	10.2%
123	Varicocele	10.2%
124	Morphea	10.2%
125	Cerebrovascular Disorders	10.1%
126	Diabetic Angiopathies	10.1%
127	Reperfusion Injury	10.1%
128	Splenic Infarction	10.1%
129	Cerebrovascular Insufficiency	10.1%
130	Vascular Neoplasms	10.1%
131	Spinal Cord Vascular Diseases	10.1%
132	Vasoplegia	10.1%
133	Hemorrhoids	10%
134	Mastocytosis	10%
135	Respiratory Hypersensitivity	10%
136	Thoracic Outlet Syndrome	10%
137	Primary Ciliary Dyskinesia	10%
138	Acrodermatitis	10%
139	Gianotti-Crosti Syndrome	10%
140	Amino Acid Metabolism, Inborn Errors	9.9%
141	Carbohydrate Metabolism, Inborn Errors	9.9%
142	Metal Metabolism, Inborn Errors	9.9%
143	Progeria	9.9%
144	Lysosomal Storage Diseases	9.9%
145	Cytochrome-c Oxidase Deficiency	9.9%
146	Peroxisomal Disorders	9.9%
147	Acute Chest Syndrome	9.9%
148	May-Thurner Syndrome	9.9%
149	Intracranial Embolism and Thrombosis	9.9%
150	Polycystic Kidney Diseases	9.9%
151	Carotid Stenosis	9.8%
152	Intracranial Aneurysm	9.8%
153	Aortic Aneurysm, Abdominal	9.8%
154	Aortic Aneurysm, Thoracic	9.8%
155	Vasculitis, Central Nervous System	9.8%
156	Coronary Thrombosis	9.8%
157	Coronary Artery Disease	9.8%
158	Homocystinuria	9.8%
159	Amyloid Neuropathies, Familial	9.8%
160	Galactosemias	9.8%
161	Urea Cycle Disorders, Inborn	9.8%
162	Tyrosinemias	9.8%
163	Chronic granulomatous disease	9.7%
164	Gaucher Disease	9.4%
165	Kallmann Syndrome	9.4%
166	Dermatitis Herpetiformis	9.3%
167	Asthma, Aspirin-Induced	9.2%
168	Varicose Ulcer	9.1%
169	Breast Diseases	9.1%
170	Dermatitis	9.1%
171	Exanthema	9.1%
172	Facial Dermatoses	9.1%
173	Hair Diseases	9.1%
174	Hand Dermatoses	9.1%
175	Immune Complex Diseases	9.1%
176	keratoacanthoma	9.1%
177	Keratosis	9.1%
178	Nail Diseases	9.1%
179	Photosensitivity Disorders	9.1%
180	Prurigo	9.1%
181	Pyoderma	9.1%
182	Rosacea	9.1%
183	Sebaceous Gland Diseases	9.1%
184	Skin Diseases, Vesiculobullous	9.1%
185	Skin Ulcer	9.1%
186	Sweat Gland Diseases	9.1%
187	Skin Diseases, Papulosquamous	9.1%
188	Acneiform Eruptions	9.1%
189	Ocular Rosacea	9.1%
190	Latex allergy	9.1%
191	Subcorneal pustular dermatosis	9.1%
192	Erythematotelangiectatic Rosacea	9.1%
193	Papulopustular Rosacea	9.1%
194	Chronic Actinic Dermatitis	9.1%
195	Retinal Dysplasia	9.1%
196	Aniridia	9%
197	Tay-Sachs Disease	9%
198	Optic Atrophy, Hereditary, Leber	8.9%
199	Hand-Arm Vibration Syndrome	8.9%
200	Hyperphosphaturia	8.9%
201	Coronary heart disease	8.8%
202	Myocardial Infarction	8.8%
203	Acute Coronary Syndrome	8.8%
204	CREST Syndrome	8.8%
205	Optic Neuropathy, Ischemic	8.7%
206	Anterior Ischemic Optic Neuropathy	8.7%
207	Mesenteric vascular insufficiency	8.7%
208	Retinitis Pigmentosa	8.6%
209	Pigmentary retinopathy	8.6%
210	Classical Lissencephalies and Subcortical Band Heterotopias	8.6%
211	Canavan Disease	8.5%
212	Alexander Disease	8.5%
213	Colitis, Ischemic	8.5%
214	Niemann-Pick Disease, Type C	8.5%
215	Zellweger Syndrome	8.4%
216	Welander Distal Myopathy	8.4%
217	Leigh Disease	8.4%
218	Intracranial Arteriosclerosis	8.4%
219	Cerebral Atherosclerosis	8.4%
220	Cerebral Arteriosclerosis	8.4%
221	Peutz-Jeghers Syndrome	8.4%
222	Acne Vulgaris	8.3%
223	Contact Dermatitis	8.3%
224	Eczema	8.3%
225	Erythema Multiforme	8.3%
226	Intertrigo	8.3%
227	Neurodermatitis	8.3%
228	Rhinophyma	8.3%
229	Perioral Dermatitis	8.3%
230	Acne	8.3%
231	Deformity	8.3%
232	Alkaptonuria	8.2%
233	Glycogen Storage Disease	8.2%
234	Hypophosphatasia	8.2%
235	Propionic acidemia	8.2%
236	Dihydropyrimidine Dehydrogenase Deficiency	8.2%
237	Cystinosis	8.2%
238	Polycystic Kidney, Autosomal Dominant	8.1%
239	Variegate Porphyria	8%
240	Acute intermittent porphyria	8%
241	Porphyria Cutanea Tarda	8%
242	Aneurysm, Dissecting	7.9%
243	Arteriosclerosis	7.9%
244	Arteritis	7.9%
245	Embolism	7.9%
246	Erythromelalgia	7.9%
247	Fibromuscular Dysplasia	7.9%
248	Malignant Hypertension	7.9%
249	Raynaud Disease	7.9%
250	Thromboembolism	7.9%
251	Thrombosis	7.9%
252	Essential Hypertension	7.9%
253	Aneurysm, Ruptured	7.9%
254	Iliac Aneurysm	7.9%
255	Pulmonary artery stenosis	7.9%
256	White Coat Hypertension	7.9%
257	Systemic Vasculitis	7.9%
258	Embolus	7.9%
259	Carbamoyl-Phosphate Synthase I Deficiency Disease	7.9%
260	Dextrocardia	7.9%
261	Foot Diseases	7.8%
262	Environmental Illness	7.8%
263	Dermatitis, Allergic Contact	7.7%
264	Cerebral Thrombosis	7.7%
265	Intracranial Embolism	7.7%
266	Intracranial Thrombosis	7.7%
267	Skin Diseases, Infectious	7.6%
268	Skin Neoplasms	7.6%
269	Pigmentation Disorders	7.6%
270	Turner Syndrome	7.6%
271	Duane Retraction Syndrome	7.6%
272	Lipomatosis	7.5%
273	Pruritus	7.5%
274	Erythema	7.5%
275	Necrolytic Migratory Erythema	7.5%
276	Cutaneous Fistula	7.5%
277	Nephrogenic Fibrosing Dermopathy	7.5%
278	Nephrogenic Systemic Fibrosis	7.5%
279	Angina Pectoris	7.5%
280	Dermatomyositis	7.5%
281	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	7.5%
282	Noonan Syndrome	7.5%
283	Myotonia Congenita	7.4%
284	Thrombasthenia	7.4%
285	Antithrombin III Deficiency	7.4%
286	Protein C Deficiency	7.4%
287	Brain Diseases, Metabolic, Inborn	7.4%
288	Afibrinogenemia	7.4%
289	Dystonia Musculorum Deformans	7.4%
290	Factor VII Deficiency	7.4%
291	Factor X Deficiency	7.4%
292	Factor XII Deficiency	7.4%
293	Hemophilia A	7.4%
294	Leukomalacia, Periventricular	7.4%
295	Activated Protein C Resistance	7.4%
296	Factor II deficiency	7.4%
297	Factor VIII Deficiency	7.4%
298	Factor V deficiency	7.4%
299	Factor XI Deficiency	7.4%
300	Hypoprothrombinemias	7.4%
301	Fanconi Anemia	7.4%
302	Lafora Disease	7.4%
303	Unverricht-Lundborg Syndrome	7.4%
304	Dermatitis, Photoallergic	7.3%
305	Anemia, Diamond-Blackfan	7.3%
306	Glycogen Storage Disease Type I	7.3%
307	Glycogen Storage Disease Type V	7.3%
308	Brain Infarction	7.3%
309	Charcot-Marie-Tooth Disease	7.3%
310	Antley-Bixler Syndrome Phenotype	7.3%
311	Hydrops Fetalis	7.2%
312	Lemierre Syndrome	7.2%
313	Embolism, Amniotic Fluid	7.1%
314	Drug Eruptions	7.1%
315	Sebaceous Gland Neoplasms	7.1%
316	Subarachnoid Hemorrhage, Traumatic	7%
317	Carotid Artery, Internal, Dissection	7%
318	Tricuspid Atresia	7%
319	Arrhythmogenic Right Ventricular Dysplasia	7%
320	Hypolipoproteinemias	7%
321	Hyperlipidemia, Familial Combined	7%
322	Hyperlipoproteinemia Type III	7%
323	Fetal Diseases	6.9%
324	Milk Allergy	6.9%
325	Wheat Hypersensitivity	6.9%
326	Heart Diseases	6.9%
327	Necrobiosis Lipoidica Diabeticorum	6.8%
328	Multiple Endocrine Neoplasia	6.8%
329	Erythema Nodosum	6.8%
330	Serum Sickness	6.8%
331	Infarction, Middle Cerebral Artery	6.7%
332	Infarction, Anterior Cerebral Artery	6.7%
333	Infarction, Posterior Cerebral Artery	6.7%
334	Pemphigus	6.7%
335	Retinal Artery Occlusion	6.7%
336	Retinal Vasculitis	6.7%
337	Hypertensive Retinopathy	6.7%
338	Congenital Hypothyroidism	6.7%
339	Klinefelter Syndrome	6.6%
340	Anterior Compartment Syndrome	6.6%
341	Gastric Antral Vascular Ectasia	6.6%
342	Abdominal Compartment Syndrome	6.6%
343	Sinus Thrombosis, Intracranial	6.6%
344	Carotid Artery Diseases	6.6%
345	Brain Ischemia	6.6%
346	Hypotension, Orthostatic	6.6%
347	Cerebrovascular accident	6.6%
348	Foot Ulcer	6.6%
349	Vasospasm, Intracranial	6.6%
350	Spinal Cord Ischemia	6.6%
351	Intracranial Arterial Diseases	6.6%
352	Primary Graft Dysfunction	6.6%
353	Post-Exercise Hypotension	6.6%
354	Panniculitis, Lupus Erythematosus	6.6%
355	Coronary Occlusion	6.6%
356	Microvascular Angina	6.6%
357	Coronary Stenosis	6.6%
358	Vertebral Artery Dissection	6.6%
359	ST segment elevation myocardial infarction	6.6%
360	Dermatitis, Phototoxic	6.3%
361	Pityriasis Lichenoides et Varioliformis Acuta	6.3%
362	Pityriasis Lichenoides	6.3%
363	Phototoxicity	6.3%
364	Hypoalphalipoproteinemias	6.3%
365	Dural Arteriovenous Fistula	6.2%
366	Familial Periodic Paralysis	6.2%
367	Lactose Intolerance	6.1%
368	Diabetic Foot	6.1%
369	Aortic coarctation	6.1%
370	Cor Triatriatum	6.1%
371	Coronary Vessel Anomalies	6.1%
372	Patent ductus arteriosus	6.1%
373	Ebstein Anomaly	6.1%
374	Heart Septal Defects	6.1%
375	Tetralogy of Fallot	6.1%
376	Transposition of Great Vessels	6.1%
377	Hypoplastic Left Heart Syndrome	6.1%
378	Hyperhomocysteinemia	6.1%
379	Renal Aminoacidurias	6.1%
380	Fanconi Syndrome	6.1%
381	Pseudohypoaldosteronism	6.1%
382	Liddle Syndrome	6.1%
383	Erythema Induratum	6.1%
384	Hyperlipoproteinemia Type IV	6.1%
385	Hyperlipoproteinemia Type V	6.1%
386	Basal Cell Nevus Syndrome	6.1%
387	Cavernous Sinus Thrombosis	6.1%
388	Sagittal Sinus Thrombosis	6.1%
389	Cerebral Infarction	6.1%
390	Brain Stem Infarctions	6.1%
391	Meconium Aspiration Syndrome	6%
392	MELAS Syndrome	6%
393	Cryoglobulinemia	6%
394	Arteriosclerosis Obliterans	5.9%
395	Atherosclerosis	5.9%
396	Air Embolism	5.9%
397	Endarteritis	5.9%
398	Venous Thrombosis	5.9%
399	Deep Vein Thrombosis	5.9%
400	Venous Thromboembolism	5.9%
401	Toxic Epidermal Necrolysis	5.9%
402	Stevens-Johnson Syndrome	5.9%
403	Carotid Artery Injuries	5.9%
404	Autoimmune Diseases	5.9%
405	Connective Tissue Diseases	5.9%
406	Immunologic Deficiency Syndromes	5.9%
407	Immunoproliferative Disorders	5.9%
408	Immune reconstitution syndrome	5.9%
409	Immune Reconstitution Inflammatory Syndrome	5.9%
410	Mobius Syndrome	5.9%
411	Pregnancy Complications, Cardiovascular	5.8%
412	Mesenteric Vascular Occlusion	5.7%
413	Diabetic Retinopathy	5.7%
414	Sturge-Weber Syndrome	5.7%
415	Renal hypertension	5.7%
416	Renal Artery Obstruction	5.7%
417	Renal Artery Stenosis	5.7%
418	Hemangioma, Cavernous	5.6%
419	Shock, Cardiogenic	5.6%
420	Basal Ganglia Cerebrovascular Disease	5.6%
421	Vascular Headaches	5.6%
422	Scurvy	5.6%
423	Urticaria Pigmentosa	5.6%
424	Multiple Myeloma	5.6%
425	Angina, Unstable	5.6%
426	Gout	5.5%
427	Lupus Erythematosus, Discoid	5.5%
428	Scleroderma, Limited	5.5%
429	Hypokalemic periodic paralysis	5.5%
430	Multiple Endocrine Neoplasia Type 1	5.5%
431	Pseudohypoparathyroidism	5.5%
432	Cystinuria	5.5%
433	Friedreich Ataxia	5.4%
434	Lateral Medullary Syndrome	5.4%
435	Coronary Restenosis	5.4%
436	Renal tubular acidosis	5.4%
437	Familial Hypophosphatemic Rickets	5.4%
438	Huntington Disease	5.4%
439	Long QT Syndrome	5.4%
440	Abdominal Cramps	5.4%
441	Abnormalities, Drug-Induced	5.4%
442	Amniotic Band Syndrome	5.4%
443	Asphyxia Neonatorum	5.4%
444	Infant, Premature, Diseases	5.4%
445	Situs Inversus	5.4%
446	Infantile Colic	5.4%
447	Basal Ganglia Hemorrhage	5.3%
448	Lupus Vasculitis, Central Nervous System	5.3%
449	Anencephaly	5.2%
450	Wolff-Parkinson-White Syndrome	5.1%
451	Lupus Erythematosus, Systemic	5.1%
452	Overlap syndrome	5.1%
453	Intermittent Claudication	5%
454	Pulmonary Embolism	5%
455	Erythema Infectiosum	5%
456	Exanthema Subitum	5%
457	Ischemic contracture	5%
458	Anhidrosis	5%
459	Cholesteatoma	5%
460	Pressure Ulcer	5%
461	Folliculitis	5%
462	Foot Dermatoses	5%
463	Gynecomastia	5%
464	Hypertrichosis	5%
465	Hypohidrosis	5%
466	Hypotrichosis	5%
467	Leg Ulcer	5%
468	Miliaria	5%
469	Parakeratosis	5%
470	Parapsoriasis	5%
471	Pityriasis	5%
472	Psoriasis	5%
473	Sweet Syndrome	5%
474	Hidradenitis	5%
475	Onycholysis	5%
476	Miliaria Rubra	5%
477	Hyperpigmentation	5%
478	Lichenoid Eruptions	5%
479	Chloracne	5%
480	Ectopia Cordis	4.9%
481	No-Reflow Phenomenon	4.9%
482	Single umbilical artery	4.9%
483	Nephroblastoma	4.9%
484	Dermatitis, Irritant	4.9%
485	Acne Conglobata	4.9%
486	Transfusion Reaction	4.9%
487	Hypotensive Transfusion Reaction	4.9%
488	Cerebral Arterial Diseases	4.9%
489	Vertebrobasilar Insufficiency	4.9%
490	Anterior Spinal Artery Syndrome	4.9%
491	Basilar Artery Stenosis	4.9%
492	Vertebral Artery Stenosis	4.9%
493	Intracranial Hemorrhage, Hypertensive	4.9%
494	Transient Cerebral Ischemia	4.9%
495	Aortopulmonary Septal Defect	4.9%
496	Double Outlet Right Ventricle	4.9%
497	Endocardial Cushion Defects	4.9%
498	Myocardial bridging	4.9%
499	Aorticopulmonary Septal Defect	4.9%
500	Arthritis, Gouty	4.9%
501	Waldenstrom Macroglobulinemia	4.8%
502	Rheumatoid Vasculitis	4.7%
503	Granulomatosis with polyangiitis	4.7%
504	Angina Pectoris, Variant	4.6%
505	Eye Abnormalities	4.6%
506	Maxillofacial Abnormalities	4.6%
507	Putaminal Hemorrhage	4.6%
508	Lymphatic Abnormalities	4.5%
509	Congenital Microtia	4.5%
510	Adenomatous Polyposis Coli	4.5%
511	Anemia, Neonatal	4.5%
512	Persistent Fetal Circulation Syndrome	4.5%
513	Congenital diaphragmatic hernia	4.4%
514	Umbilical hernia	4.4%
515	Dementia, Vascular	4.4%
516	Glycosuria, Renal	4.4%
517	Aortic Valve Stenosis	4.4%
518	Cardiomyopathy, Dilated	4.4%
519	Pulmonary Valve Stenosis	4.4%
520	Asthma	4.4%
521	Ecthyma	4.4%
522	Shy-Drager Syndrome	4.4%
523	Purpura, Hyperglobulinemic	4.4%
524	Dermatitis, Occupational	4.3%
525	Truncus Arteriosus, Persistent	4.3%
526	Tinea Capitis	4.3%
527	Onychomycosis	4.3%
528	Romano-Ward Syndrome	4.3%
529	Granuloma Annulare	4.2%
530	Bacterial Endocarditis	4.2%
531	Acute Generalized Exanthematous Pustulosis	4.2%
532	Hypertension, Renovascular	4.2%
533	Subarachnoid Hemorrhage	4.2%
534	Hypoxia-Ischemia, Brain	4.2%
535	Cerebral Hemorrhage	4.2%
536	Acantholysis	4.2%
537	Breast Cyst	4.2%
538	Actinic keratosis	4.2%
539	Pemphigoid, Benign Mucous Membrane	4.2%
540	Piedra	4.2%
541	Sick Building Syndrome	4.2%
542	Sunburn	4.2%
543	Multiple Chemical Sensitivity	4.2%
544	Hepatic Vein Thrombosis	4.2%
545	Budd-Chiari Syndrome	4.2%
546	Argyria	4.1%
547	Hirsutism	4.1%
548	Lactation Disorder	4.1%
549	Mastitis	4.1%
550	Acrocephalosyndactylia	4.1%
551	Adiposis Dolorosa	4.1%
552	Pruritus Vulvae	4.1%
553	Mastocytoma	4.1%
554	Pruritus Ani	4.1%
555	Pulmonary Infarction	4.1%
556	Glomerulonephritis, Membranoproliferative	4.1%
557	Subclavian Steal Syndrome	4.1%
558	Cardiac Tamponade	4%
559	Endocarditis	4%
560	Cardiac Arrest	4%
561	Heart failure	4%
562	Pericardial effusion	4%
563	Pericarditis	4%
564	Pneumopericardium	4%
565	Cor pulmonale	4%
566	Ventricular Outflow Obstruction	4%
567	Ventricular Dysfunction	4%
568	Cardiomyopathies	4%
569	Pleuropericarditis	4%
570	Urogenital Abnormalities	4%
571	Prune Belly Syndrome	4%
572	Twins, Conjoined	4%
573	Waardenburg Syndrome	4%
574	Denys-Drash Syndrome	3.9%
575	Neonatal Abstinence Syndrome	3.9%
576	Microcephaly	3.9%
577	Macrocephaly	3.9%
578	Aspergillosis, Allergic Bronchopulmonary	3.9%
579	Fetal Growth Retardation	3.8%
580	Fetal Hypoxia	3.8%
581	Congenital nystagmus	3.8%
582	Fetal Alcohol Spectrum Disorders	3.8%
583	Heart Block	3.8%
584	Tachycardia	3.8%
585	Tachyarrhythmia	3.8%
586	Toxoplasmosis, Congenital	3.8%
587	Syphilis, Congenital	3.8%
588	Pituitary Apoplexy	3.7%
589	Porencephaly	3.7%
590	Craniosynostosis	3.6%
591	Syndactyly	3.6%
592	Brachycephaly	3.6%
593	Dermatomycoses	3.6%
594	Skin Diseases, Bacterial	3.6%
595	Hypertrophic Cardiomyopathy	3.6%
596	Hypertrophic obstructive cardiomyopathy	3.6%
597	Erythema Chronicum Migrans	3.6%
598	Lipodystrophy	3.6%
599	Kernicterus	3.5%
600	POEMS Syndrome	3.5%
601	Cerebral Amyloid Angiopathy	3.5%
602	Cleft Palate	3.5%
603	Cardiac Output, High	3.4%
604	Myocardial Stunning	3.4%
605	Low Cardiac Output Syndrome	3.4%
606	Anophthalmos	3.4%
607	Anus, Imperforate	3.4%
608	Cardiomegaly	3.4%
609	Hydranencephaly	3.4%
610	Microphthalmos	3.4%
611	Neural Tube Defects	3.4%
612	Paralysis, Obstetric	3.4%
613	Postpericardiotomy Syndrome	3.4%
614	Retinopathy of Prematurity	3.4%
615	Tethered Cord Syndrome	3.4%
616	Iniencephaly	3.4%
617	Craniorachischisis	3.4%
618	Limb Deformities, Congenital	3.4%
619	Exencephaly	3.4%
620	Septo-Optic Dysplasia	3.4%
621	Craniofacial Abnormalities	3.4%
622	Cortical Dysplasia	3.4%
623	Cardiac Hypertrophy	3.4%
624	Malformations of Cortical Development	3.4%
625	Anorectal Malformations	3.4%
626	Congenital Hyperinsulinism	3.3%
627	Chorioamnionitis	3.3%
628	Rheumatic Heart Disease	3.3%
629	Bloom Syndrome	3.3%
630	Bronchopulmonary Dysplasia	3.3%
631	Asthma, Exercise-Induced	3.3%
632	Status Asthmaticus	3.3%
633	Hidradenitis Suppurativa	3.3%
634	Supravalvular aortic stenosis	3.3%
635	Lown-Ganong-Levine Syndrome	3.3%
636	Diaper Rash	3.3%
637	Sick Sinus Syndrome	3.3%
638	Poland Syndrome	3.2%
639	Laryngomalacia	3.2%
640	Pectus carinatum	3.2%
641	Jaw Abnormalities	3.2%
642	Thrombocytopenic purpura	3.2%
643	Collagen Diseases	3%
644	Mixed Connective Tissue Disease	3%
645	Antiphospholipid Syndrome	3%
646	Mucinoses	3%
647	Lichen Planus	3%
648	Melanosis	3%
649	Chloasma	3%
650	Pityriasis Rosea	3%
651	Pityriasis Rubra Pilaris	3%
652	Vitiligo	3%
653	Lichen Nitidus	3%
654	Asthma, Occupational	3%
655	Rheumatoid Arthritis	3%
656	Juvenile arthritis	3%
657	Abnormalities, Radiation-Induced	2.9%
658	Blepharophimosis	2.9%
659	Farmer's Lung	2.9%
660	Laryngostenosis	2.9%
661	Mouth Abnormalities	2.9%
662	Respiratory Distress Syndrome, Newborn	2.9%
663	Esophageal Atresia	2.9%
664	Intestinal Atresia	2.9%
665	Horseshoe Kidney	2.9%
666	Pectus excavatum	2.9%
667	Hay fever	2.9%
668	Rhinitis, Allergic, Perennial	2.9%
669	Klippel-Feil Syndrome	2.9%
670	Gastroschisis	2.9%
671	Synostosis	2.9%
672	Micrognathism	2.9%
673	Pierre Robin Syndrome	2.9%
674	Lymphangiectasis, Intestinal	2.8%
675	Adams-Stokes Syndrome	2.8%
676	Atrioventricular Block	2.8%
677	Bundle-Branch Block	2.8%
678	Atrial Premature Complexes	2.8%
679	Sinoatrial Block	2.8%
680	Tachycardia, Paroxysmal	2.8%
681	Supraventricular tachycardia	2.8%
682	Tachycardia, Ventricular	2.8%
683	Tachycardia, Reciprocating	2.8%
684	Amelia	2.7%
685	Arachnodactyly	2.7%
686	Ectromelia	2.7%
687	Hemimelia	2.7%
688	Meningomyelocele	2.7%
689	Phocomelia	2.7%
690	Sirenomelia	2.7%
691	Spina Bifida	2.7%
692	Polydactyly	2.7%
693	Brachydactyly	2.7%
694	Plagiocephaly	2.7%
695	Lower Extremity Deformities, Congenital	2.7%
696	Upper Extremity Deformities, Congenital	2.7%
697	Tinea Pedis	2.7%
698	Autoimmune thrombocytopenia	2.7%
699	Immune thrombocytopenic purpura	2.7%
700	Bronchomalacia	2.7%
701	Tracheomalacia	2.7%
702	Mycetoma	2.7%
703	Aortic Valve Insufficiency	2.6%
704	Restrictive cardiomyopathy	2.6%
705	Endocardial Fibroelastosis	2.6%
706	Heart Rupture, Post-Infarction	2.6%
707	Mitral Valve Insufficiency	2.6%
708	Mitral Valve Stenosis	2.6%
709	Myocarditis	2.6%
710	Pericarditis, Constrictive	2.6%
711	Pulmonary Valve Insufficiency	2.6%
712	Tricuspid Valve Insufficiency	2.6%
713	Tricuspid Valve Stenosis	2.6%
714	Ventricular Dysfunction, Left	2.6%
715	Right Ventricular Dysfunction	2.6%
716	Endomyocardial Fibrosis	2.6%
717	Carditis	2.6%
718	Heart Failure, Systolic	2.6%
719	Heart Failure, Diastolic	2.6%
720	Ophthalmia Neonatorum	2.6%
721	Cartilage Diseases	2.6%
722	Rheumatism	2.6%
723	Chondromalacia	2.6%
724	Retrognathia	2.6%
725	Subacute Bacterial Endocarditis	2.6%
726	Arthrogryposis	2.6%
727	Choanal Atresia	2.6%
728	Tracheobronchomegaly	2.6%
729	Laryngocele	2.6%
730	Lymphoproliferative Disorders	2.5%
731	Choledochal Cyst	2.5%
732	Hermaphroditism	2.5%
733	Disorders of Sex Development	2.5%
734	Addison Disease	2.5%
735	Paraproteinemias	2.5%
736	Autoimmune thyroiditis	2.5%
737	Primary Adrenal Insufficiency	2.5%
738	Cryptorchidism	2.5%
739	Hypospadias	2.5%
740	Alopecia	2.5%
741	Lymphopenia	2.5%
742	Sweating, Gustatory	2.5%
743	Androgenetic Alopecia	2.5%
744	Auriculotemporal Syndrome	2.5%
745	Central Nervous System Cysts	2.5%
746	Autoimmune hepatitis	2.5%
747	Dandy-Walker Syndrome	2.5%
748	Lice Infestations	2.5%
749	Breast Neoplasms, Male	2.5%
750	Triple Negative Breast Neoplasms	2.5%
751	Nesidioblastosis	2.5%
752	Galactorrhea	2.5%
753	Carcinoid Heart Disease	2.5%
754	Dermal Sinus	2.5%
755	Spina Bifida Cystica	2.5%
756	Spina Bifida Occulta	2.5%
757	Mastocytosis, Systemic	2.5%
758	Lissencephaly	2.5%
759	Polymicrogyria	2.5%
760	Pachygyria	2.5%
761	Schizencephaly	2.5%
762	Periventricular Nodular Heterotopia	2.5%
763	Hematoma, Subdural	2.4%
764	Hematoma, Epidural, Cranial	2.4%
765	Hyperandrogenism	2.4%
766	Prognathism	2.4%
767	Dental Enamel Hypoplasia	2.4%
768	Hyaline Membrane Disease	2.4%
769	Hypodontia	2.4%
770	Macrostomia	2.4%
771	Meningocele	2.4%
772	Microstomia	2.4%
773	Encephalocele	2.4%
774	Craniofacial Dysostosis	2.3%
775	Tachycardia, Atrioventricular Nodal Reentry	2.3%
776	Tachycardia, Ectopic Atrial	2.3%
777	Tachycardia, Ectopic Junctional	2.3%
778	Sinus Tachycardia	2.3%
779	Torsades de Pointes	2.3%
780	Accelerated Idioventricular Rhythm	2.3%
781	HIV-Associated Lipodystrophy Syndrome	2.3%
782	Bladder Exstrophy	2.2%
783	Epispadias	2.2%
784	Brain Hemorrhage, Traumatic	2.2%
785	Sinus Arrhythmia	2.2%
786	Atrial Fibrillation	2.2%
787	Atrial Flutter	2.2%
788	Edema, Cardiac	2.2%
789	Ventricular Fibrillation	2.2%
790	Ventricular Flutter	2.2%
791	Parasystole	2.2%
792	Paroxysmal atrial fibrillation	2.2%
793	Bradycardia	2.2%
794	Diabetic Cardiomyopathies	2.2%
795	Multicystic Dysplastic Kidney	2.2%
796	Cardiomyopathy, Alcoholic	2.2%
797	Sudden Cardiac Death	2.2%
798	Left Ventricular Hypertrophy	2.2%
799	Right Ventricular Hypertrophy	2.2%
800	Chagas Cardiomyopathy	2.2%
801	Hypergammaglobulinemia	2.2%
802	Hematoma, Subdural, Intracranial	2.2%
803	Hematoma, Subdural, Chronic	2.2%
804	Hematoma, Subdural, Acute	2.2%
805	Latent Autoimmune Diabetes in Adults	2.2%
806	Agammaglobulinemia	2.2%
807	HIV Infections	2.1%
808	Larva Migrans	2.1%
809	Leishmaniasis	2.1%
810	Molluscum Contagiosum	2.1%
811	Transfusion-Related Acute Lung Injury	2.1%
812	Dupuytren Contracture	2.1%
813	Onchocerciasis	2.1%
814	Chromoblastomycosis	2.1%
815	Dermatophytosis	2.1%
816	Sporotrichosis	2.1%
817	Tinea	2.1%
818	Tinea Versicolor	2.1%
819	Trichophytosis	2.1%
820	Hyalohyphomycosis	2.1%
821	Platybasia	2.1%
822	Primary amyloidosis	2.1%
823	Gonadal Dysgenesis	2.1%
824	Monoclonal Gammopathy of Undetermined Significance	2.1%
825	Adrenogenital Syndrome	2.1%
826	Ovotesticular Disorders of Sex Development	2.1%
827	Lupus Nephritis	2%
828	Aortic Valve Prolapse	2%
829	Tricuspid Valve Prolapse	2%
830	Takotsubo Cardiomyopathy	2%
831	Goldenhar Syndrome	2%
832	Acanthosis Nigricans	2%
833	Alopecia Areata	2%
834	Lentigo	2%
835	Warts	1.9%
836	Dyspnea, Paroxysmal	1.9%
837	Graves Disease	1.9%
838	Cellulitis	1.9%
839	Anti-Glomerular Basement Membrane Disease	1.9%
840	Candidiasis, Chronic Mucocutaneous	1.9%
841	Cutaneous Candidiasis	1.9%
842	Erysipelas	1.8%
843	Staphylococcal Skin Infections	1.8%
844	Erythrasma	1.8%
845	Carcinoma, Lobular	1.8%
846	Mandibulofacial Dysostosis	1.8%
847	Arthritis, Psoriatic	1.8%
848	Talipes	1.7%
849	Congenital clubfoot	1.7%
850	Vertical Talus	1.7%
851	Lichen Planus, Oral	1.7%
852	Scleromyxedema	1.7%
853	Felty Syndrome	1.6%
854	Sinus Arrest, Cardiac	1.6%
855	Blastomycosis	1.5%
856	Leishmaniasis, Cutaneous	1.4%
857	Eczema Herpeticum	1.4%
858	Mesenteric Panniculitis	1.4%
859	Panniculitis, Peritoneal	1.4%
860	Tietze's Syndrome	1.4%
861	Orbital Cellulitis	1.4%
862	Myxoid cyst	1.4%
863	Fusariosis	1.4%
864	Myxedema	1.4%
865	Plasmacytoma	1.4%
866	Tumor Lysis Syndrome	1.4%
867	HTLV-I Infections	1.4%
868	Job Syndrome	1.4%
869	Rhinoscleroma	1.4%
870	Sicca Syndrome	1.3%
871	Sjogren's Syndrome	1.3%
872	Epidermodysplasia Verruciformis	1.2%
873	Herpes Labialis	1.2%
874	Staphylococcal Scalded Skin Syndrome	1.2%
875	Osteochondritis	1.2%
876	Polymyalgia Rheumatica	1.2%
877	Lymphoma	1.2%
878	Myasthenia Gravis	1.2%
879	Uveomeningoencephalitic Syndrome	1.2%
880	Heavy Chain Disease	1.2%
881	Keloid	1.2%
882	HIV Seropositivity	1.2%
883	Sezary Syndrome	1.1%
884	Condylomata Acuminata	1.1%
885	Furunculosis	1.1%
886	furuncle	1.1%
887	Impetigo	1.1%
888	Stiff-Person Syndrome	1.1%
889	Polyradiculoneuropathy	1.1%
890	Polyradiculoneuritis	1.1%
891	Acquired Immunodeficiency Syndrome	1%
892	AIDS related complex	1%
893	Infectious Mononucleosis	1%
894	Schnitzler Syndrome	1%
895	Myasthenia Gravis, Autoimmune, Experimental	1%
896	AIDS-Related Opportunistic Infections	0.9%
897	Kearns-Sayre syndrome	0.9%
898	HIV Wasting Syndrome	0.9%
899	AIDS Dementia Complex	0.9%
900	AIDS-Associated Nephropathy	0.9%
901	carbuncle	0.9%
902	Lambert-Eaton Myasthenic Syndrome	0.8%
903	Multiple Sclerosis	0.7%
904	Hodgkin Disease	0.7%
905	Leukemia, Plasma Cell	0.7%
906	Lymphoma, Non-Hodgkin	0.7%
907	Rheumatoid Nodule	0.7%
908	Leukemia, T-Cell	0.7%
909	Leukemia, B-Cell	0.7%
910	Neuromyelitis Optica	0.7%
911	Leukoencephalitis, Acute Hemorrhagic	0.7%
912	Composite Lymphoma	0.6%
913	Encephalomyelitis, Acute Disseminated	0.6%
914	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	0.6%
915	Neuritis, Autoimmune, Experimental	0.6%
916	Lymphangioleiomyomatosis	0.6%
917	Guillain-Barre Syndrome	0.5%
918	Multiple Sclerosis, Chronic Progressive	0.5%
919	Multiple Sclerosis, Relapsing-Remitting	0.5%
920	Lymphoma, Follicular	0.5%
921	T-Cell Lymphoma	0.5%
922	Mantle cell lymphoma	0.5%
923	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	0.5%
924	Leukemia, Large Granular Lymphocytic	0.5%
925	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	0.5%
926	Myelitis, Transverse	0.4%
927	Lymphoma, T-Cell, Cutaneous	0.3%
928	Lymphoma, AIDS-Related	0.3%
929	Enteropathy-Associated T-Cell Lymphoma	0.3%
930	Primary Effusion Lymphoma	0.3%
931	Lymphomatoid Granulomatosis	0.3%
932	Mycosis Fungoides	0.3%
933	Lymphomatoid Papulosis	0.3%
934	Plasmablastic lymphoma	0.3%
935	Miller Fisher Syndrome	0.3%
936	Burkitt Lymphoma	0.3%

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