MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Pachygyria

(UMLS:C0266483)

UMLS ID:: C0266483
MeSH ID:: D054082

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.500.507.450.499

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.666.507.450.499

Synonym(s)

Pachygyria

Cerebral pachygyria

Fewer and broader ridges in brain

Macrogyria

macrogyria

pachygyria

Associated Drug(s)

	Name	Number of Reports	Data Source
1	efavirenz	FAERS: 5	US FAERS
2	Valproic Acid	FAERS: 4	US FAERS
3	Cabergoline	FAERS: 1	US FAERS
4	Oxcarbazepine	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Periventricular Nodular Heterotopia	48.8%
2	Classical Lissencephalies and Subcortical Band Heterotopias	28.5%
3	Hydranencephaly	27%
4	Neural Tube Defects	27%
5	Tethered Cord Syndrome	27%
6	Iniencephaly	27%
7	Craniorachischisis	27%
8	Exencephaly	27%
9	Septo-Optic Dysplasia	27%
10	Polymicrogyria	23.2%
11	Schizencephaly	23.2%
12	Dural Arteriovenous Fistula	20.4%
13	Dandy-Walker Syndrome	20%
14	Central Nervous System Cysts	19.6%
15	Microcephaly	18%
16	Macrocephaly	18%
17	Anencephaly	17.6%
18	Porencephaly	17.1%
19	Aicardi's syndrome	15.9%
20	Meningomyelocele	15.8%
21	Spina Bifida	15.8%
22	Holoprosencephaly	15.1%
23	Abnormalities, Drug-Induced	14.9%
24	Situs Inversus	14.9%
25	Tuberous Sclerosis	12.8%
26	Meningocele	12.7%
27	Encephalocele	12.7%
28	Smith-Magenis syndrome	12.5%
29	Eye Abnormalities	11.8%
30	Cardiovascular Abnormalities	11.8%
31	Beckwith-Wiedemann Syndrome	11.5%
32	Wolf-Hirschhorn Syndrome	11.5%
33	Skin Abnormalities	11.4%
34	Lymphatic Abnormalities	11.4%
35	Congenital Microtia	11.4%
36	Charcot-Marie-Tooth Disease	11.3%
37	Congenital diaphragmatic hernia	11.1%
38	Cri-du-Chat Syndrome	10.6%
39	Down Syndrome	10.6%
40	Trisomy 21	10.6%
41	Cranial nerve diseases	10.4%
42	Demyelinating Diseases	10.4%
43	Demyelination	10.4%
44	Neuromuscular Diseases	10.4%
45	Chronobiology Disorders	10.4%
46	Dermal Sinus	10.4%
47	Spina Bifida Cystica	10.4%
48	Spina Bifida Occulta	10.4%
49	Genetic Diseases, Inborn	9.8%
50	Alstrom Syndrome	9.7%
51	Urogenital Abnormalities	9.5%
52	Prader-Willi Syndrome	9.1%
53	Rubinstein-Taybi Syndrome	8.7%
54	Motor Neuron Disease	8.4%
55	Mobius Syndrome	8.3%
56	Ectodermal Dysplasia	8.2%
57	Aplasia Cutis Congenita	8.2%
58	Trauma, Nervous System	8.1%
59	Prune Belly Syndrome	8.1%
60	Twins, Conjoined	8.1%
61	Waardenburg Syndrome	8.1%
62	CHARGE Syndrome	8%
63	Nervous System Neoplasms	7.9%
64	Neurologic Manifestations	7.9%
65	Neurotoxicity Syndromes	7.9%
66	Fetal Diseases	7.4%
67	Stiff-Person Syndrome	7.3%
68	Refsum Disease	7.2%
69	Multiple System Atrophy	7.2%
70	Ocular Motility Disorders	7%
71	Cyclophoria	7%
72	Nail-Patella Syndrome	6.7%
73	Restless Legs Syndrome	6.7%
74	Polyradiculoneuropathy	6.7%
75	Polyradiculoneuritis	6.7%
76	Xeroderma	6.6%
77	Encephalomyelitis	6.6%
78	Prion Diseases	6.6%
79	Autonomic Dysreflexia	6.6%
80	Complex Regional Pain Syndromes	6.6%
81	Maxillofacial Abnormalities	6.6%
82	Dextrocardia	6.5%
83	Williams Syndrome	6.5%
84	Sleep Wake Disorders	6.4%
85	Cockayne Syndrome	6.4%
86	Abnormalities, Radiation-Induced	6.3%
87	Anophthalmos	6.2%
88	Anus, Imperforate	6.2%
89	Microphthalmos	6.2%
90	Limb Deformities, Congenital	6.2%
91	Craniofacial Abnormalities	6.2%
92	Myasthenic Syndromes, Congenital	6.2%
93	Anorectal Malformations	6.2%
94	Subacute Combined Degeneration	6.2%
95	Bloom Syndrome	6.1%
96	Marfan Syndrome	6.1%
97	Spinal Muscular Atrophy	5.9%
98	Progressive Muscular Atrophy	5.9%
99	Marchiafava-Bignami Disease	5.8%
100	Kartagener Syndrome	5.7%
101	Amyotrophic Lateral Sclerosis	5.6%
102	Ophthalmoplegic Migraine	5.6%
103	Parkinson Disease	5.6%
104	Spinal Cord Injuries	5.5%
105	Brain Diseases	5.5%
106	Dysautonomia	5.5%
107	Meningitis	5.5%
108	Movement Disorders	5.5%
109	Pachymeningitis	5.5%
110	Spinal Cord Diseases	5.5%
111	Vagus Nerve Disorder	5.5%
112	Glossopharyngeal Neuralgia	5.5%
113	Abducens Nerve Diseases	5.5%
114	Heavy Metal Poisoning, Nervous System	5.5%
115	Neuromuscular Junction Diseases	5.5%
116	Tauopathies	5.5%
117	Trochlear Nerve Diseases	5.5%
118	Peripheral Nervous System Diseases	5.5%
119	Meningoencephalitis	5.4%
120	Polycystic Kidney Diseases	5.4%
121	Peripheral Nerve Injuries	5.4%
122	Myasthenia Gravis	5.3%
123	Asterixis	5.3%
124	Ballismus	5.3%
125	Cystic Fibrosis	5.2%
126	Dystonia Musculorum Deformans	5.1%
127	POEMS Syndrome	5.1%
128	Scimitar Syndrome	5.1%
129	Blepharophimosis	5.1%
130	Laryngostenosis	5.1%
131	Mouth Abnormalities	5.1%
132	Esophageal Atresia	5%
133	Intestinal Atresia	5%
134	Horseshoe Kidney	5%
135	Pectus excavatum	5%
136	Abdominal Cramps	5%
137	Amniotic Band Syndrome	5%
138	Asphyxia Neonatorum	5%
139	Infant, Premature, Diseases	5%
140	Infantile Colic	5%
141	Klippel-Feil Syndrome	5%
142	Gastroschisis	5%
143	Synostosis	5%
144	Acrodermatitis	4.9%
145	Lymphangiectasis, Intestinal	4.9%
146	Gianotti-Crosti Syndrome	4.9%
147	Lewy Body Disease	4.9%
148	Pneumocephalus	4.9%
149	Poliomyelitis	4.9%
150	Myelitis	4.9%
151	Progressive bulbar palsy	4.9%
152	Bulbar palsy	4.9%
153	Guillain-Barre Syndrome	4.9%
154	Retinal Dysplasia	4.8%
155	Fragile X Syndrome	4.8%
156	Aniridia	4.8%
157	Epidermolysis Bullosa	4.7%
158	Chronic Fatigue Syndrome	4.6%
159	Neuroleptic Malignant Syndrome	4.6%
160	Myelinolysis, Central Pontine	4.6%
161	Sleep Disorders, Circadian Rhythm	4.6%
162	Striatonigral Degeneration	4.6%
163	Lambert-Eaton Myasthenic Syndrome	4.6%
164	Causalgia	4.5%
165	Ataxia Telangiectasia	4.4%
166	Botulism	4.4%
167	Central Nervous System Infection	4.4%
168	Myopathy	4.4%
169	Optic Neuropathy	4.4%
170	Meconium Aspiration Syndrome	4.4%
171	Epidural Abscess	4.3%
172	Olfactory Nerve Injuries	4.3%
173	Progressive supranuclear palsy	4.3%
174	Muscular Dystrophy	4.3%
175	Congenital nystagmus	4.3%
176	Arthrogryposis	4.2%
177	Choanal Atresia	4.2%
178	Tracheobronchomegaly	4.2%
179	Laryngocele	4.2%
180	Smith-Lemli-Opitz Syndrome	4.2%
181	Myelitis, Transverse	4.2%
182	Facial Nerve Diseases	4.2%
183	Craniocerebral Trauma	4.2%
184	Parasomnia	4.2%
185	Dyssomnias	4.2%
186	MPTP Poisoning	4.2%
187	Choledochal Cyst	4.2%
188	Hermaphroditism	4.2%
189	Disorders of Sex Development	4.2%
190	Craniosynostosis	4.2%
191	Myotonic Dystrophy	4.2%
192	Syndactyly	4.2%
193	Brachycephaly	4.2%
194	Lafora Disease	4.2%
195	Unverricht-Lundborg Syndrome	4.2%
196	Dyskinesia, Drug-Induced	4.2%
197	Cryptorchidism	4.2%
198	Hypospadias	4.2%
199	Vestibulocochlear Nerve Diseases	4.1%
200	Decerebrate State	4.1%
201	Hemiparesis	4.1%
202	Meningism	4.1%
203	Paresis	4.1%
204	Seizures	4.1%
205	Sensation Disorders	4.1%
206	Central Nervous System Neoplasms	4.1%
207	Complex partial seizures	4.1%
208	Monoparesis	4.1%
209	Neurogenic Inflammation	4.1%
210	Gait Disorders, Neurologic	4.1%
211	Neuromuscular Manifestations	4.1%
212	Sweating, Gustatory	4.1%
213	Auriculotemporal Syndrome	4.1%
214	Leukoencephalitis, Acute Hemorrhagic	4.1%
215	Myotonia Congenita	4.1%
216	Primary Ciliary Dyskinesia	4.1%
217	Encephalomyelitis, Acute Disseminated	4.1%
218	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	4.1%
219	Reflex Sympathetic Dystrophy	4%
220	Subdural Effusion	4%
221	Parkinsonian Disorders	4%
222	Nocturnal Myoclonus Syndrome	4%
223	Opsoclonus-Myoclonus Syndrome	4%
224	Ichthyosis, X-Linked	4%
225	Huntington Disease	4%
226	Miller Fisher Syndrome	4%
227	Canavan Disease	3.9%
228	Alexander Disease	3.9%
229	Shy-Drager Syndrome	3.9%
230	Brain Injuries	3.9%
231	Neoplastic Syndromes, Hereditary	3.9%
232	Toxoplasmosis, Congenital	3.9%
233	Brain Neoplasms	3.9%
234	Multiple Sclerosis	3.9%
235	Spinal Cord Neoplasms	3.9%
236	Neuromyelitis Optica	3.9%
237	Horner Syndrome	3.8%
238	Akathisia, Drug-Induced	3.8%
239	Hepatolenticular Degeneration	3.8%
240	Anemia, Neonatal	3.7%
241	Multiple Epiphyseal Dysplasia	3.7%
242	Osteochondrodysplasias	3.7%
243	Pelger-Huet Anomaly	3.7%
244	Persistent Fetal Circulation Syndrome	3.7%
245	Werner Syndrome	3.7%
246	Facial Nerve Injuries	3.7%
247	Noonan Syndrome	3.7%
248	Umbilical hernia	3.7%
249	Pseudoxanthoma Elasticum	3.7%
250	Amelia	3.6%
251	Arachnodactyly	3.6%
252	Ectopia Cordis	3.6%
253	Ectromelia	3.6%
254	Hemimelia	3.6%
255	Phocomelia	3.6%
256	Sirenomelia	3.6%
257	Polydactyly	3.6%
258	Brachydactyly	3.6%
259	Plagiocephaly	3.6%
260	Lower Extremity Deformities, Congenital	3.6%
261	Upper Extremity Deformities, Congenital	3.6%
262	Single umbilical artery	3.6%
263	Laryngomalacia	3.6%
264	Pectus carinatum	3.6%
265	Bladder Exstrophy	3.5%
266	Epispadias	3.5%
267	Leukomalacia, Periventricular	3.5%
268	Multicystic Dysplastic Kidney	3.5%
269	Muscular Dystrophy, Duchenne	3.5%
270	Pupil Disorders	3.5%
271	Neurobehavioral Manifestations	3.5%
272	Leukoencephalopathy, Progressive Multifocal	3.4%
273	Paraneoplastic Encephalomyelitis	3.4%
274	Xeroderma Pigmentosum	3.3%
275	Uveomeningoencephalitic Syndrome	3.3%
276	Vasculitis, Central Nervous System	3.3%
277	Brain Abscess	3.3%
278	Ophthalmoplegia	3.3%
279	External Ophthalmoplegia	3.3%
280	Scrapie	3.3%
281	Sturge-Weber Syndrome	3.3%
282	Vertigo	3.3%
283	Central Cord Syndrome	3.3%
284	Alcohol-Induced Disorders, Nervous System	3.3%
285	Jet Lag Syndrome	3.3%
286	Zellweger Syndrome	3.3%
287	Presenile dementia	3.3%
288	Senile dementia	3.3%
289	Meningitis, Bacterial	3.3%
290	Meningitis, Fungal	3.3%
291	Limbic Encephalitis	3.2%
292	Myasthenia Gravis, Autoimmune, Experimental	3.2%
293	Akinetic Mutism	3.2%
294	Anoxic Encephalopathy	3.2%
295	Arachnoiditis	3.2%
296	Basal Ganglia Diseases	3.2%
297	Brain Damage, Chronic	3.2%
298	Cerebellar Diseases	3.2%
299	Encephalitis	3.2%
300	Encephalomalacia	3.2%
301	Epilepsy	3.2%
302	Hydrocephalus	3.2%
303	Congenital Hydrocephalus	3.2%
304	Hypothalamic Diseases	3.2%
305	Aseptic Meningitis	3.2%
306	Neuritis	3.2%
307	Polyneuritis	3.2%
308	Radiculitis	3.2%
309	Syringomyelia	3.2%
310	Thalamic Diseases	3.2%
311	Intracranial Hypertension	3.2%
312	Polyneuropathy	3.2%
313	Mononeuritis	3.2%
314	Aura	3.2%
315	Leukoencephalopathy	3.2%
316	Essential Tremor	3.2%
317	Neuroaxonal Dystrophies	3.2%
318	Familial Tremor	3.2%
319	Headache Disorders	3.2%
320	Mononeuropathies	3.2%
321	Intracranial Hypotension	3.2%
322	Brachial Plexus Neuropathies	3.2%
323	Radiculopathy	3.2%
324	Mononeuropathy Multiplex	3.2%
325	Nerve Root Compression	3.2%
326	Brain Edema	3.2%
327	Brain Hypoxia	3.2%
328	Aqueductal Stenosis	3.2%
329	Pneumorrhachis	3.2%
330	Writer's Cramp	3.2%
331	Chorea	3.2%
332	Amyloid Neuropathies, Familial	3.2%
333	Acrodynia	3.2%
334	Friedreich Ataxia	3.2%
335	Epilepsy, Post-Traumatic	3.2%
336	Meige Syndrome	3.2%
337	Brachial Plexus Neuritis	3.2%
338	Neuralgic Amyotrophy	3.2%
339	Cerebral Ventriculitis	3.2%
340	Polycystic Kidney, Autosomal Dominant	3.2%
341	Acrocephalosyndactylia	3.2%
342	Dwarfism	3.1%
343	Turner Syndrome	3.1%
344	Jaw Abnormalities	3.1%
345	Sjogren-Larsson Syndrome	3.1%
346	Duane Retraction Syndrome	3.1%
347	Neonatal Abstinence Syndrome	3.1%
348	Kallmann Syndrome	3.1%
349	Neuronal Ceroid-Lipofuscinoses	3%
350	Fetal Growth Retardation	3%
351	Osteogenesis Imperfecta	3%
352	Fetal Hypoxia	3%
353	Fetal Alcohol Spectrum Disorders	3%
354	Basal Cell Nevus Syndrome	3%
355	Aortic coarctation	2.9%
356	Cor Triatriatum	2.9%
357	Coronary Vessel Anomalies	2.9%
358	Dental Enamel Hypoplasia	2.9%
359	Patent ductus arteriosus	2.9%
360	Ebstein Anomaly	2.9%
361	Heart Septal Defects	2.9%
362	Hypodontia	2.9%
363	Macrostomia	2.9%
364	Microstomia	2.9%
365	Syphilis, Congenital	2.9%
366	Tetralogy of Fallot	2.9%
367	Transposition of Great Vessels	2.9%
368	Hypoplastic Left Heart Syndrome	2.9%
369	May-Thurner Syndrome	2.9%
370	Craniofacial Dysostosis	2.9%
371	Wolff-Parkinson-White Syndrome	2.9%
372	Rett Syndrome	2.9%
373	Cleft Palate	2.9%
374	Vocal Cord Paralysis	2.9%
375	Lupus Vasculitis, Central Nervous System	2.9%
376	Voice Disorders	2.8%
377	Voice Disturbance	2.8%
378	Adrenoleukodystrophy	2.8%
379	Tarsal Tunnel Syndrome	2.8%
380	Cauda Equina Syndrome	2.8%
381	Posterior Leukoencephalopathy Syndrome	2.8%
382	Posterior reversible encephalopathy syndrome	2.8%
383	Antley-Bixler Syndrome Phenotype	2.8%
384	Brain Death	2.8%
385	Coma, Post-Head Injury	2.8%
386	Poland Syndrome	2.7%
387	Amblyopia	2.7%
388	Anemia, Sickle Cell	2.7%
389	Thalassemia	2.7%
390	Paraneoplastic Cerebellar Degeneration	2.7%
391	Familial Mediterranean Fever	2.7%
392	Cerebrospinal Fluid Otorrhea	2.7%
393	Cerebrospinal Fluid Rhinorrhea	2.7%
394	Neuritis, Autoimmune, Experimental	2.7%
395	Gait Ataxia	2.7%
396	Cerebellar Neoplasms	2.7%
397	Creutzfeldt-Jakob disease	2.6%
398	Basal Ganglia Cerebrovascular Disease	2.6%
399	Dementia, Vascular	2.6%
400	Brain Hemorrhage, Traumatic	2.6%
401	Welander Distal Myopathy	2.6%
402	Brain Injuries, Diffuse	2.6%
403	Traumatic Brain Injury	2.6%
404	Cerebellar Ataxia	2.6%
405	Supratentorial Neoplasms	2.6%
406	Torticollis	2.6%
407	Multiple Sclerosis, Chronic Progressive	2.6%
408	Multiple Sclerosis, Relapsing-Remitting	2.6%
409	Autoimmune Lymphoproliferative Syndrome	2.5%
410	Klinefelter Syndrome	2.5%
411	Congenital Hyperinsulinism	2.5%
412	Brain Diseases, Metabolic	2.5%
413	Cerebrovascular Disorders	2.5%
414	Myositis	2.5%
415	Optic Atrophy	2.5%
416	Optic Neuritis	2.5%
417	Papilledema	2.5%
418	Strabismus	2.5%
419	Tolosa-Hunt Syndrome	2.5%
420	Cerebrovascular Insufficiency	2.5%
421	Isaacs syndrome	2.5%
422	Arsenic Poisoning	2.5%
423	Dementia	2.5%
424	Myotonic Disorders	2.5%
425	Central Nervous System Fungal Infections	2.5%
426	Conus Medullaris Syndrome	2.5%
427	Spinal Cord Vascular Diseases	2.5%
428	Chorioamnionitis	2.5%
429	Familial Periodic Paralysis	2.5%
430	Angioedemas, Hereditary	2.5%
431	Long QT Syndrome	2.5%
432	Platybasia	2.5%
433	Tricuspid Atresia	2.5%
434	Arrhythmogenic Right Ventricular Dysplasia	2.5%
435	Brain Diseases, Metabolic, Inborn	2.5%
436	Diabetic Neuropathies	2.4%
437	Facial Injuries	2.4%
438	Facial Neuralgia	2.4%
439	Diabetic Amyotrophy	2.4%
440	Diabetic Autonomic Neuropathy	2.4%
441	Sleep Talking	2.4%
442	Manganese Poisoning	2.4%
443	Sleep Disorders, Intrinsic	2.4%
444	Orthostatic intolerance	2.4%
445	Gonadal Dysgenesis	2.4%
446	Bronchomalacia	2.4%
447	Adrenogenital Syndrome	2.4%
448	Alcohol Withdrawal Seizures	2.4%
449	Tracheomalacia	2.4%
450	Ovotesticular Disorders of Sex Development	2.4%
451	Anosmia	2.4%
452	Ataxia	2.4%
453	Athetosis	2.4%
454	Catalepsy	2.4%
455	Dystonia	2.4%
456	Hemiplegia	2.4%
457	Locked-In Syndrome	2.4%
458	Meningeal Neoplasms	2.4%
459	Muscle Hypertonia	2.4%
460	Muscle hypotonia	2.4%
461	Myoclonus	2.4%
462	Myotonia	2.4%
463	Neuralgia	2.4%
464	Paraplegia	2.4%
465	Pseudobulbar Palsy	2.4%
466	Quadriplegia	2.4%
467	Spasm	2.4%
468	Spastic Paraplegia	2.4%
469	Status Epilepticus	2.4%
470	Taste Disorders	2.4%
471	Tremor	2.4%
472	Monoplegia	2.4%
473	Hypokinesia	2.4%
474	Paraparesis	2.4%
475	Bradykinesia	2.4%
476	Waxy flexibility	2.4%
477	Action Tremor	2.4%
478	Resting Tremor	2.4%
479	Dysosmia	2.4%
480	Quadriparesis	2.4%
481	Mercury Poisoning, Nervous System	2.4%
482	Olfaction Disorders	2.4%
483	Myokymia	2.4%
484	Lead Poisoning, Nervous System	2.4%
485	Vestibular Neuronitis	2.4%
486	Somatosensory Disorders	2.4%
487	Neuropathic pain	2.4%
488	Hyperkinesia	2.4%
489	Intention tremor	2.4%
490	Carotid Artery Injuries	2.4%
491	Menkes Kinky Hair Syndrome	2.4%
492	Hyperkeratosis, Epidermolytic	2.4%
493	Myoclonic Epilepsy	2.4%
494	Epilepsy, Temporal Lobe	2.4%
495	Epilepsy, Rolandic	2.4%
496	Benign Rolandic Epilepsy	2.4%
497	Albinism	2.4%
498	Reflex, Abnormal	2.3%
499	Hyporeflexia	2.3%
500	Hyperreflexia	2.3%
501	Optic Atrophy, Hereditary, Leber	2.3%
502	Akathisia	2.3%
503	Restlessness	2.3%
504	Psychomotor Agitation	2.3%
505	Tuberculosis, Meningeal	2.3%
506	Carpal Tunnel Syndrome	2.3%
507	Vascular Headaches	2.3%
508	neurofibroma	2.2%
509	Hypoxia-Ischemia, Brain	2.2%
510	Sciatica	2.2%
511	Tardive Dyskinesia	2.2%
512	Persistent Vegetative State	2.2%
513	Cerebral Palsy	2.1%
514	Epilepsies, Partial	2.1%
515	Epilepsy, Generalized	2.1%
516	Pseudotumor Cerebri	2.1%
517	Sciatic Neuropathy	2.1%
518	Hypertensive Encephalopathy	2.1%
519	Ulnar Neuropathies	2.1%
520	Lesion of Sciatic Nerve	2.1%
521	Simple Partial Seizures	2.1%
522	Epilepsy, Reflex	2.1%
523	Ulnar Neuritis	2.1%
524	Radial nerve compression	2.1%
525	Radial Tunnel Syndrome	2.1%
526	Peroneal Neuropathies	2.1%
527	Radial Neuropathy	2.1%
528	Median Neuropathy	2.1%
529	Sciatic Nerve Palsy	2.1%
530	Femoral Neuropathy	2.1%
531	Tibial Neuropathy	2.1%
532	Ulnar Nerve Palsy	2.1%
533	Postural Orthostatic Tachycardia Syndrome	2.1%
534	Radial nerve palsy	2.1%
535	Headache Disorders, Primary	2.1%
536	Headache Disorders, Secondary	2.1%
537	Medication overuse headache	2.1%
538	Micrognathism	2.1%
539	Pierre Robin Syndrome	2.1%
540	Alice in Wonderland Syndrome	2.1%
541	Vertebral Artery Dissection	2.1%
542	Mucopolysaccharidosis II	2.1%
543	Amnesia, Transient Global	2.1%
544	Hand-Arm Vibration Syndrome	2.1%
545	Paralysis, Obstetric	2.1%
546	Retinopathy of Prematurity	2.1%
547	Gait Apraxia	2.1%
548	Amino Acid Metabolism, Inborn Errors	2%
549	Carbohydrate Metabolism, Inborn Errors	2%
550	Metal Metabolism, Inborn Errors	2%
551	Progeria	2%
552	Wiskott-Aldrich Syndrome	2%
553	Lysosomal Storage Diseases	2%
554	Cytochrome-c Oxidase Deficiency	2%
555	Peroxisomal Disorders	2%
556	Vision Disorders	2%
557	Metamorphopsia	2%
558	Visual Impairment	2%
559	Bronchopulmonary Dysplasia	2%
560	Fibromyalgia	2%
561	Optic Neuropathy, Ischemic	2%
562	Anterior Ischemic Optic Neuropathy	2%
563	Central Nervous System Bacterial Infections	2%
564	Medial Tibial Stress Syndrome	2%
565	Brain Concussion	2%
566	Optic Nerve Glioma	2%
567	Facial Hemiatrophy	2%
568	Melkersson-Rosenthal Syndrome	2%
569	Mitochondrial Myopathies	2%
570	Juvenile Myoclonic Epilepsy	2%
571	Myoclonic Epilepsies, Progressive	2%
572	Anisocoria	2%
573	Confusion	2%
574	Facial paralysis	2%
575	Lethargy	2%
576	Memory Disorders	2%
577	Muscle Cramp	2%
578	Perceptual Disorders	2%
579	Psychomotor Disorders	2%
580	Tonic Pupil	2%
581	Eosinophilia-Myalgia Syndrome	2%
582	Anhedonia	2%
583	Disorientation	2%
584	Facial Paresis	2%
585	Memory Loss	2%
586	Hemisensory Neglect	2%
587	Dysacusis	2%
588	Toxoplasmosis, Cerebral	2%
589	Sleep Bruxism	2%
590	Muscular Atrophy	2%
591	Respiratory Paralysis	2%
592	Tetany	1.9%
593	Aortopulmonary Septal Defect	1.9%
594	Double Outlet Right Ventricle	1.9%
595	Endocardial Cushion Defects	1.9%
596	Myocardial bridging	1.9%
597	Aorticopulmonary Septal Defect	1.9%
598	Hyperandrogenism	1.9%
599	Cubital Tunnel Syndrome	1.9%
600	Diffuse Axonal Injury	1.9%
601	Brain Stem Neoplasms	1.9%
602	Retrognathia	1.9%
603	Meningitis, Cryptococcal	1.9%
604	Meningitis, Listeria	1.9%
605	Meningitis, Haemophilus	1.9%
606	Meningitis, Pneumococcal	1.9%
607	Frontotemporal dementia	1.9%
608	Kernicterus	1.9%
609	Mitochondrial Encephalomyopathies	1.9%
610	Ophthalmia Neonatorum	1.8%
611	Galactosemias	1.8%
612	Urea Cycle Disorders, Inborn	1.8%
613	Tyrosinemias	1.8%
614	Pituitary Adenoma	1.8%
615	Pituitary Neoplasms	1.8%
616	Acoustic Neuroma	1.8%
617	MELAS Syndrome	1.7%
618	Prognathism	1.7%
619	Pituitary Diseases	1.7%
620	Basal Ganglia Hemorrhage	1.7%
621	Respiratory Distress Syndrome, Newborn	1.7%
622	Fabry Disease	1.7%
623	Consciousness Disorders	1.7%
624	Mental Retardation	1.7%
625	Muscle Weakness	1.7%
626	Depressed Level of Consciousness	1.7%
627	Mental deficiency	1.7%
628	Intellectual Disability	1.7%
629	Bell Palsy	1.7%
630	Cutis Laxa	1.7%
631	Catatonia	1.7%
632	Retinitis Pigmentosa	1.7%
633	Pigmentary retinopathy	1.7%
634	Herpes Zoster Oticus	1.6%
635	Thoracic Outlet Syndrome	1.6%
636	Porokeratosis	1.6%
637	Keratoderma, Palmoplantar	1.6%
638	Aphonia	1.6%
639	Sleep Deprivation	1.6%
640	Dysphonia	1.6%
641	Chronic granulomatous disease	1.6%
642	Pituitary Apoplexy	1.6%
643	Auditory Perceptual Disorders	1.6%
644	Carotid Artery Diseases	1.6%
645	Brain Ischemia	1.6%
646	Esotropia	1.6%
647	Exotropia	1.6%
648	Hypotension, Orthostatic	1.6%
649	Sleep Apnea Syndromes	1.6%
650	Cerebrovascular accident	1.6%
651	Polymyositis	1.6%
652	Kluver-Bucy Syndrome	1.6%
653	Vasospasm, Intracranial	1.6%
654	Spinal Cord Ischemia	1.6%
655	Intracranial Arterial Diseases	1.6%
656	Post-Exercise Hypotension	1.6%
657	Giant Cell Arteritis	1.6%
658	Temporal Arteritis	1.6%
659	Hypokalemic periodic paralysis	1.6%
660	Mandibulofacial Dysostosis	1.6%
661	Disorders of Excessive Somnolence	1.6%
662	Sleep Initiation and Maintenance Disorders	1.6%
663	Night Terrors	1.6%
664	Somnambulism	1.6%
665	Trigeminal Nerve Disorder	1.6%
666	Transient Insomnia	1.6%
667	Sleep Paralysis	1.6%
668	Chronic Insomnia	1.6%
669	REM Sleep Behavior Disorder	1.6%
670	Hypersomnia	1.6%
671	Romano-Ward Syndrome	1.6%
672	Brain Contusion	1.6%
673	Sickle Cell Trait	1.6%
674	Dysgeusia	1.6%
675	Formication	1.6%
676	Hyperalgesia	1.6%
677	Hyperesthesia	1.6%
678	Hypesthesia	1.6%
679	Language Disorders	1.6%
680	Numbness	1.6%
681	Paresthesia	1.6%
682	Paraparesis, Spastic	1.6%
683	Trismus	1.6%
684	Epilepsia Partialis Continua	1.6%
685	Hypogeusia	1.6%
686	Meningeal Carcinomatosis	1.6%
687	Brown-Sequard Syndrome	1.6%
688	Lockjaw	1.6%
689	Allodynia	1.6%
690	Lead Poisoning, Nervous System, Childhood	1.6%
691	Lead Poisoning, Nervous System, Adult	1.6%
692	Brain Infarction	1.6%
693	Ageusia	1.6%
694	Tuberculosis, Central Nervous System	1.6%
695	Polyradiculopathy	1.6%
696	Post-Traumatic Headache	1.6%
697	Tension Headache	1.6%
698	Epilepsy, Complex Partial	1.6%
699	Migraine Disorders	1.6%
700	Abdominal Migraine	1.6%
701	Status Migrainosus	1.6%
702	Cervicogenic Headache	1.6%
703	Subarachnoid Hemorrhage, Traumatic	1.6%
704	Carotid Artery, Internal, Dissection	1.6%
705	Choroid Plexus Papilloma	1.6%
706	Subacute Sclerosing Panencephalitis	1.5%
707	Homocystinuria	1.4%
708	Putaminal Hemorrhage	1.4%
709	Truncus Arteriosus, Persistent	1.4%
710	Leigh Disease	1.4%
711	Goldenhar Syndrome	1.4%
712	Myalgia	1.4%
713	Porphyrias, Hepatic	1.4%
714	Infarction, Middle Cerebral Artery	1.4%
715	Infarction, Anterior Cerebral Artery	1.4%
716	Infarction, Posterior Cerebral Artery	1.4%
717	Alexia	1.4%
718	Dyslexia	1.4%
719	Peutz-Jeghers Syndrome	1.4%
720	Thrombasthenia	1.4%
721	Antithrombin III Deficiency	1.4%
722	Protein C Deficiency	1.4%
723	Afibrinogenemia	1.4%
724	Factor VII Deficiency	1.4%
725	Factor X Deficiency	1.4%
726	Factor XII Deficiency	1.4%
727	Hemophilia A	1.4%
728	Activated Protein C Resistance	1.4%
729	Factor II deficiency	1.4%
730	Factor VIII Deficiency	1.4%
731	Factor V deficiency	1.4%
732	Factor XI Deficiency	1.4%
733	Hypoprothrombinemias	1.4%
734	Glycogen storage disease type II	1.4%
735	Fanconi Anemia	1.3%
736	Nesidioblastosis	1.3%
737	Eye Injuries	1.3%
738	Anemia, Diamond-Blackfan	1.3%
739	Cluster Headache	1.3%
740	Migraine with Aura	1.3%
741	Familial Hemiplegic Migraine	1.3%
742	Chronic Paroxysmal Hemicrania	1.3%
743	SUNCT Syndrome	1.3%
744	Paroxysmal Hemicrania	1.3%
745	Cerebral Infarction	1.3%
746	Brain Stem Infarctions	1.3%
747	Orbital Myositis	1.3%
748	Diplopia	1.3%
749	Muscle Rigidity	1.3%
750	Muscle Spasticity	1.3%
751	Scotoma	1.3%
752	Photophobia	1.3%
753	Cogwheel Rigidity	1.3%
754	Hemifacial Spasm	1.3%
755	Amaurosis	1.3%
756	Blindness	1.3%
757	Nuchal Rigidity	1.3%
758	Reye Syndrome	1.3%
759	Neuroaspergillosis	1.3%
760	Pyomyositis	1.3%
761	Hematoma, Subdural	1.3%
762	Hematoma, Epidural, Cranial	1.3%
763	Intracranial Embolism and Thrombosis	1.3%
764	Hepatic Encephalopathy	1.3%
765	Agnosia	1.3%
766	Apraxias	1.3%
767	Hallucinations	1.3%
768	Hemianopsia	1.3%
769	Hyperacusis	1.3%
770	Tinnitus	1.3%
771	Visual Agnosia	1.3%
772	Anosognosia	1.3%
773	Wernicke-Korsakoff Syndrome	1.3%
774	Phonophobia	1.3%
775	Hearing Loss	1.3%
776	Sarcopenia	1.3%
777	Hydrops Fetalis	1.3%
778	Moyamoya Disease	1.3%
779	Neurofibrosarcoma	1.2%
780	Hoarseness	1.2%
781	Acute Chest Syndrome	1.2%
782	Empty Sella Syndrome	1.2%
783	Hyperpituitarism	1.2%
784	Hypopituitarism	1.2%
785	Hypophysitis	1.2%
786	Alcohol Withdrawal Delirium	1.2%
787	Arteriovenous fistula	1.2%
788	Talipes	1.2%
789	Multiple Endocrine Neoplasia	1.2%
790	Alkaptonuria	1.2%
791	Glycogen Storage Disease	1.2%
792	Hypophosphatasia	1.2%
793	Propionic acidemia	1.2%
794	Dihydropyrimidine Dehydrogenase Deficiency	1.2%
795	Cystinosis	1.2%
796	Kearns-Sayre syndrome	1.2%
797	Cerebral Arterial Diseases	1.2%
798	Vertebrobasilar Insufficiency	1.2%
799	Anterior Spinal Artery Syndrome	1.2%
800	Basilar Artery Stenosis	1.2%
801	Vertebral Artery Stenosis	1.2%
802	Sleep Apnea, Obstructive	1.2%
803	Sleep Apnea, Central	1.2%
804	Intracranial Hemorrhage, Hypertensive	1.2%
805	Transient Cerebral Ischemia	1.2%
806	Narcolepsy	1.2%
807	Trigeminal Neuralgia	1.2%
808	Kleine-Levin Syndrome	1.2%
809	Agraphia	1.2%
810	Anomia	1.2%
811	Cluttering	1.2%
812	Language Development Disorders	1.2%
813	Speech Disorders	1.2%
814	Syncope	1.2%
815	Stupor	1.2%
816	Dysgraphia	1.2%
817	Presyncope	1.2%
818	Dyslalia	1.2%
819	Lateral Medullary Syndrome	1.2%
820	Congenital Hypothyroidism	1.2%
821	Dermatitis, Atopic	1.2%
822	West Nile Fever	1.2%
823	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.2%
824	Pseudorabies	1.1%
825	Amnesia	1.1%
826	Delirium	1.1%
827	Dissociative Amnesia	1.1%
828	Color blindness	1.1%
829	Global Amnesia	1.1%
830	Meningioma	1.1%
831	Neurosyphilis	1.1%
832	Hyperphosphaturia	1.1%
833	Hematoma, Subdural, Intracranial	1%
834	Hematoma, Subdural, Chronic	1%
835	Hematoma, Subdural, Acute	1%
836	Behcet Syndrome	1%
837	Denys-Drash Syndrome	1%
838	Hyperprolactinemia	1%
839	Congenital clubfoot	1%
840	Vertical Talus	1%
841	Subclavian Steal Syndrome	1%
842	Pick Disease of the Brain	1%
843	Cataplexy	1%
844	Aphasia	1%
845	Articulation Disorders	1%
846	Echolalia	1%
847	Stuttering	1%
848	Dysphasia	1%
849	Eye Burns	1%
850	Hyaline Membrane Disease	1%
851	Malaria, Cerebral	1%
852	Gaucher Disease	1%
853	Carotid Stenosis	1%
854	Intracranial Aneurysm	1%
855	Hypolipoproteinemias	1%
856	Papillon-Lefevre Disease	1%
857	Neurocysticercosis	1%
858	Amaurosis Fugax	1%
859	Blindness, Cortical	1%
860	Dyscalculia	1%
861	Intracranial Arteriosclerosis	1%
862	Cerebral Atherosclerosis	1%
863	Hyperlipidemia, Familial Combined	1%
864	Subarachnoid Hemorrhage	1%
865	Cerebral Arteriosclerosis	1%
866	Cerebral Hemorrhage	1%
867	Hyperlipoproteinemia Type III	1%
868	Cerebral Thrombosis	1%
869	Intracranial Embolism	1%
870	Intracranial Thrombosis	1%
871	Deafness	1%
872	Hearing Loss, Sudden	1%
873	Gerstmann Syndrome	1%
874	Hearing Loss, Bilateral	1%
875	Hearing Loss, High-Frequency	1%
876	Hearing Loss, Mixed Conductive-Sensorineural	1%
877	Prosopagnosia	1%
878	Apraxia, Ideomotor	1%
879	Charles Bonnet Syndrome	1%
880	Hearing Loss, Unilateral	1%
881	Complete Hearing Loss	1%
882	Alien Hand Syndrome	1%
883	Deaf Mutism	1%
884	Wernicke Encephalopathy	0.9%
885	AIDS Dementia Complex	0.9%
886	Phantom pain	0.9%
887	Phantom Limb Pain	0.9%
888	Lyme Neuroborreliosis	0.9%
889	Mucopolysaccharidosis III	0.9%
890	Dysarthria	0.9%
891	Dermatomyositis	0.8%
892	Corneal Scar	0.8%
893	Nephroblastoma	0.8%
894	Mutism	0.8%
895	Selective Mutism	0.8%
896	Acromegaly	0.8%
897	Lactose Intolerance	0.8%
898	Variegate Porphyria	0.8%
899	Acute intermittent porphyria	0.8%
900	Porphyria Cutanea Tarda	0.8%
901	Hyperhomocysteinemia	0.8%
902	Waterhouse-Friderichsen Syndrome	0.8%
903	Retrograde amnesia	0.8%
904	Amnesia, Anterograde	0.8%
905	Renal Aminoacidurias	0.8%
906	Fanconi Syndrome	0.8%
907	Pseudohypoaldosteronism	0.8%
908	Liddle Syndrome	0.8%
909	Carotid Artery Thrombosis	0.8%
910	Hyperlipoproteinemia Type IV	0.8%
911	Hyperlipoproteinemia Type V	0.8%
912	Cerebral Amyloid Angiopathy	0.8%
913	Glycogen Storage Disease Type I	0.8%
914	Glycogen Storage Disease Type V	0.8%
915	Sinus Thrombosis, Intracranial	0.8%
916	Tay-Sachs Disease	0.8%
917	Niemann-Pick Disease, Type C	0.8%
918	Adenomatous Polyposis Coli	0.7%
919	Alexia, Pure	0.7%
920	Cavernous Sinus Thrombosis	0.7%
921	Sagittal Sinus Thrombosis	0.7%
922	Gout	0.7%
923	Multiple Endocrine Neoplasia Type 1	0.7%
924	Pseudohypoparathyroidism	0.7%
925	Renal tubular acidosis	0.7%
926	Corneal Perforation	0.7%
927	Hypoalphalipoproteinemias	0.6%
928	Nelson Syndrome	0.6%
929	Prolactinoma	0.6%
930	Growth Hormone-Secreting Pituitary Adenoma	0.6%
931	Glycosuria, Renal	0.5%
932	Cystinuria	0.5%
933	Arthritis, Gouty	0.5%
934	Familial Hypophosphatemic Rickets	0.5%

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