MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Retinopathy of Prematurity

(UMLS:C0035344)

Definition:: A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
UMLS ID:: C0035344
MeSH ID:: D012178

Classification 1:

Name:

Eye Diseases
MeSH Tree Number(s):: C11.768.836

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.614.521.731

Synonym(s)

Retinopathy of Prematurity

RETROLENTAL FIBROPLASIA

RLF

RLF - Retrolental fibroplasia

ROP - Retinopathy of prematurity

Retinopathy of prematurity

Retinopathy of prematurity, unspecified

Retrolental Fibroplasia

Retrolental fibroplasia

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Indomethacin	FAERS: 64		SIDER US FAERS
2	Oxygen	FAERS: 41	View details 16303979 22148982 25203536 25375125	CTD US FAERS
3	Paroxetine	FAERS: 7		US FAERS
4	Ibuprofen	FAERS: 5		US FAERS
5	Olmesartan Medoxomil	FAERS: 5		US FAERS
6	Clomiphene	FAERS: 4		US FAERS
7	Methotrexate	FAERS: 4		US FAERS
8	Sertraline	FAERS: 4		US FAERS
9	Ondansetron	FAERS: 3		US FAERS
10	Sildenafil Citrate	FAERS: 3		US FAERS
11	entecavir	FAERS: 3		US FAERS
12	Sildenafil Citrate	FAERS: 2		US FAERS
13	Acetaminophen	FAERS: 1		US FAERS
14	Aspirin	FAERS: 1		US FAERS
15	Bosentan	FAERS: 1		US FAERS
16	Fluoxetine	FAERS: 1		US FAERS
17	Hydrocortisone	FAERS: 1		US FAERS
18	Methamphetamine	FAERS: 1		US FAERS
19	Methamphetamine	FAERS: 1		US FAERS
20	Methimazole	FAERS: 1		US FAERS
21	Oseltamivir	FAERS: 1		US FAERS
22	Tacrolimus	FAERS: 1		US FAERS
23	Topiramate	FAERS: 1		US FAERS
24	sapropterin	FAERS: 1		US FAERS
25	treprostinil	FAERS: 1		US FAERS
26	Ampicillin			OFFSIDES
27	Atazanavir Sulfate			OFFSIDES
28	Caffeine			SIDER
29	Ceftazidime			OFFSIDES
30	Clindamycin			OFFSIDES
31	Clobetasol			OFFSIDES
32	Clobetasol			OFFSIDES
33	Dexamethasone			OFFSIDES SIDER
34	Dexmedetomidine			OFFSIDES
35	Dobutamine			OFFSIDES
36	Epoprostenol			OFFSIDES
37	Imipramine			OFFSIDES
38	Labetalol			OFFSIDES
39	Lansoprazole			OFFSIDES
40	Methotrimeprazine			OFFSIDES
41	Nevirapine			OFFSIDES
42	Nitric Oxide			OFFSIDES
43	Paroxetine	Canada Vigilance: 1		Canada Vigilance
44	Riluzole		16303979	CTD
45	Tenofovir			OFFSIDES
46	Terbutaline			OFFSIDES
47	Vitamin E		3754046	CTD
48	Zidovudine			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Retinal Degeneration	28.1%
2	Angioid Streaks	27.9%
3	Retinal Detachment	27.9%
4	Retinitis	27.9%
5	Retinal Dysplasia	23.8%
6	Bronchopulmonary Dysplasia	23.5%
7	Retinal Hemorrhage	22.1%
8	Abdominal Cramps	20.9%
9	Amniotic Band Syndrome	20.9%
10	Asphyxia Neonatorum	20.9%
11	Infantile Colic	20.9%
12	Retinal Artery Occlusion	20.7%
13	Retinal Vasculitis	20.7%
14	Hypertensive Retinopathy	20.7%
15	Retinal Neovascularization	20.5%
16	Macular degeneration	20.5%
17	Retinal Drusen	20.5%
18	Retinal Necrosis Syndrome, Acute	20.5%
19	Retinoschisis	20.5%
20	Respiratory Distress Syndrome, Newborn	19.4%
21	Retinitis Pigmentosa	18.4%
22	Pigmentary retinopathy	18.4%
23	Chorioretinitis	18.1%
24	Retinal Vein Occlusion	16.5%
25	Eye Abnormalities	16.4%
26	Diabetic Retinopathy	16.3%
27	Congenital nystagmus	16.3%
28	Leukomalacia, Periventricular	15.6%
29	Anemia, Neonatal	15.5%
30	Persistent Fetal Circulation Syndrome	15.5%
31	Umbilical hernia	15.3%
32	Aniridia	14.7%
33	Asthenopia	14.6%
34	Conjunctival Diseases	14.6%
35	Corneal Diseases	14.6%
36	Eyelid Diseases	14.6%
37	Lacrimal Apparatus Diseases	14.6%
38	Lens Diseases	14.6%
39	Ocular Hypertension	14.6%
40	Ocular Hypotension	14.6%
41	Scleral Diseases	14.6%
42	Vitreous Detachment	14.6%
43	Posterior Vitreous Detachment	14.6%
44	Cystic Fibrosis	14.1%
45	Hyaline Membrane Disease	14.1%
46	Blepharophimosis	13.9%
47	Cytomegalovirus Retinitis	13.6%
48	Neonatal Abstinence Syndrome	12.7%
49	Xeroderma	12.5%
50	Mobius Syndrome	12.5%
51	Deformity	12.2%
52	Genetic Diseases, Inborn	12.2%
53	Toxoplasmosis, Congenital	12.1%
54	Syphilis, Congenital	12.1%
55	Xerophthalmia	12.1%
56	Low Tension Glaucoma	12.1%
57	Iridocorneal endothelial syndrome	12.1%
58	Meconium Aspiration Syndrome	11.9%
59	Retinoblastoma	11.8%
60	Ophthalmia Neonatorum	11.6%
61	Duane Retraction Syndrome	11.5%
62	Uveal Neoplasms	11.1%
63	Eyelid Neoplasms	11%
64	CHARGE Syndrome	11%
65	Eye Infection	10.9%
66	Eye Manifestations	10.9%
67	Eye Neoplasms	10.9%
68	Optic Neuropathy	10.9%
69	Keratoconjunctivitis Sicca	10.7%
70	Aicardi's syndrome	10.6%
71	Anophthalmos	10.3%
72	Microphthalmos	10.3%
73	Paralysis, Obstetric	10.3%
74	Congenital Hyperinsulinism	10.2%
75	Keratoconjunctivitis	10.2%
76	Corneal Ulcer	9.6%
77	Choroid Hemorrhage	9.5%
78	Pars Planitis	9.4%
79	Anisometropia	9.3%
80	Aphakia	9.3%
81	Astigmatism	9.3%
82	Blepharitis	9.3%
83	Blepharoptosis	9.3%
84	Blepharospasm	9.3%
85	Choroid Diseases	9.3%
86	Conjunctivitis	9.3%
87	Corneal edema	9.3%
88	Corneal Opacity	9.3%
89	Dacryocystitis	9.3%
90	Dry Eye Syndromes	9.3%
91	Ectropion	9.3%
92	Enophthalmos	9.3%
93	Entropion	9.3%
94	Episcleritis	9.3%
95	Exophthalmos	9.3%
96	Glaucoma	9.3%
97	Iris Diseases	9.3%
98	Keratitis	9.3%
99	Keratoconus	9.3%
100	Lacrimal Duct Obstruction	9.3%
101	Lens dislocation	9.3%
102	Lens Subluxation	9.3%
103	Mydriasis	9.3%
104	Myopia	9.3%
105	Presbyopia	9.3%
106	Pterygium	9.3%
107	Scleritis	9.3%
108	Uveitis	9.3%
109	Corneal Neovascularization	9.3%
110	Orbital Pseudotumor	9.3%
111	Cataract	9.3%
112	Pinguecula	9.3%
113	Trichiasis	9.3%
114	Fetal Diseases	9.1%
115	Corneal Scar	9%
116	Choroiditis	8.8%
117	Iridocyclitis	8.8%
118	Iritis	8.8%
119	Ocular Motility Disorders	8.7%
120	Cyclophoria	8.7%
121	Pupil Disorders	8.6%
122	Eye Hemorrhage	8.5%
123	Vision Disorders	8.4%
124	Metamorphopsia	8.4%
125	Visual Impairment	8.4%
126	Eye Injuries	8.3%
127	Beckwith-Wiedemann Syndrome	8.1%
128	Wolf-Hirschhorn Syndrome	8.1%
129	Hordeolum	7.9%
130	Color blindness	7.8%
131	Ichthyosis, X-Linked	7.8%
132	Trachoma	7.4%
133	Albinism	7.1%
134	Abnormalities, Drug-Induced	7%
135	Situs Inversus	7%
136	Endophthalmitis	6.9%
137	Optic Atrophy	6.9%
138	Optic Neuritis	6.9%
139	Papilledema	6.9%
140	Pemphigoid, Benign Mucous Membrane	6.9%
141	Strabismus	6.9%
142	Tolosa-Hunt Syndrome	6.9%
143	Orbital Cellulitis	6.9%
144	Retrobulbar Hemorrhage	6.9%
145	Corneal Endothelial Cell Loss	6.9%
146	Hyphema	6.8%
147	Vitreous Hemorrhage	6.8%
148	Acanthamoeba Keratitis	6.8%
149	Angle Closure Glaucoma	6.8%
150	Glaucoma, Open-Angle	6.8%
151	Panuveitis	6.8%
152	Exfoliation Syndrome	6.8%
153	Smith-Magenis syndrome	6.8%
154	Keratitis, Herpetic	6.8%
155	Bacterial conjunctivitis	6.7%
156	Cri-du-Chat Syndrome	6.7%
157	Down Syndrome	6.7%
158	Trisomy 21	6.7%
159	Holoprosencephaly	6.7%
160	Nesidioblastosis	6.6%
161	Corneal Perforation	6.6%
162	Alstrom Syndrome	6.6%
163	Sjogren-Larsson Syndrome	6.4%
164	Optic Atrophy, Hereditary, Leber	6.2%
165	Hyperkeratosis, Epidermolytic	5.9%
166	Ectodermal Dysplasia	5.8%
167	Aplasia Cutis Congenita	5.8%
168	Nail-Patella Syndrome	5.7%
169	Prader-Willi Syndrome	5.7%
170	Fragile X Syndrome	5.6%
171	Anterior uveitis	5.6%
172	Uveitis, Posterior	5.6%
173	Optic Neuropathy, Ischemic	5.6%
174	Anterior Ischemic Optic Neuropathy	5.6%
175	Rubinstein-Taybi Syndrome	5.5%
176	Neoplastic Syndromes, Hereditary	5.5%
177	Cardiovascular Abnormalities	5.5%
178	Anisocoria	5.4%
179	Tonic Pupil	5.4%
180	Eye pain	5.4%
181	Orbital Myositis	5.4%
182	Panophthalmitis	5.4%
183	Diplopia	5.4%
184	Scotoma	5.4%
185	Photophobia	5.4%
186	Amaurosis	5.4%
187	Blindness	5.4%
188	Skin Abnormalities	5.3%
189	Lymphatic Abnormalities	5.3%
190	Congenital Microtia	5.3%
191	Multiple Epiphyseal Dysplasia	5.2%
192	Osteochondrodysplasias	5.2%
193	Pelger-Huet Anomaly	5.2%
194	Werner Syndrome	5.2%
195	Myasthenic Syndromes, Congenital	5.2%
196	Congenital diaphragmatic hernia	5.1%
197	Kernicterus	5.1%
198	Esotropia	5%
199	Exotropia	5%
200	Choroidal Neovascularization	5%
201	Kartagener Syndrome	5%
202	Cockayne Syndrome	5%
203	Kearns-Sayre syndrome	5%
204	Marfan Syndrome	4.9%
205	Anencephaly	4.7%
206	Mandibulofacial Dysostosis	4.7%
207	Familial Mediterranean Fever	4.5%
208	Prune Belly Syndrome	4.5%
209	Twins, Conjoined	4.5%
210	Waardenburg Syndrome	4.5%
211	Ophthalmoplegia	4.5%
212	External Ophthalmoplegia	4.5%
213	Amblyopia	4.5%
214	Anemia, Sickle Cell	4.5%
215	Thalassemia	4.5%
216	Muscular Dystrophy, Duchenne	4.4%
217	Polycystic Kidney Diseases	4.4%
218	Williams Syndrome	4.4%
219	Urogenital Abnormalities	4.3%
220	Dwarfism	4.3%
221	Primary Ciliary Dyskinesia	4.2%
222	Smith-Lemli-Opitz Syndrome	4.1%
223	Fetal Growth Retardation	4.1%
224	Uveomeningoencephalitic Syndrome	4.1%
225	Muscular Dystrophy	4.1%
226	Osteogenesis Imperfecta	4.1%
227	Fetal Hypoxia	4.1%
228	Fetal Alcohol Spectrum Disorders	4.1%
229	Herpes Zoster Ophthalmicus	4.1%
230	Hemianopsia	4%
231	Amaurosis Fugax	4%
232	Blindness, Cortical	4%
233	Rett Syndrome	4%
234	Maxillofacial Abnormalities	4%
235	Dural Arteriovenous Fistula	4%
236	Dextrocardia	3.9%
237	Epidermolysis Bullosa	3.8%
238	Classical Lissencephalies and Subcortical Band Heterotopias	3.6%
239	Mucopolysaccharidosis II	3.6%
240	Behcet Syndrome	3.6%
241	Kallmann Syndrome	3.5%
242	Anus, Imperforate	3.4%
243	Hydranencephaly	3.4%
244	Neural Tube Defects	3.4%
245	Tethered Cord Syndrome	3.4%
246	Iniencephaly	3.4%
247	Craniorachischisis	3.4%
248	Limb Deformities, Congenital	3.4%
249	Exencephaly	3.4%
250	Septo-Optic Dysplasia	3.4%
251	Craniofacial Abnormalities	3.4%
252	Cortical Dysplasia	3.4%
253	Autoimmune Lymphoproliferative Syndrome	3.4%
254	Malformations of Cortical Development	3.4%
255	Anorectal Malformations	3.4%
256	Graves Disease	3.4%
257	Amino Acid Metabolism, Inborn Errors	3.4%
258	Bloom Syndrome	3.4%
259	Carbohydrate Metabolism, Inborn Errors	3.4%
260	Chorioamnionitis	3.4%
261	Metal Metabolism, Inborn Errors	3.4%
262	Progeria	3.4%
263	Lysosomal Storage Diseases	3.4%
264	Cytochrome-c Oxidase Deficiency	3.4%
265	Peroxisomal Disorders	3.4%
266	Horner Syndrome	3.4%
267	Angioedemas, Hereditary	3.4%
268	Wiskott-Aldrich Syndrome	3.3%
269	Sickle Cell Trait	3.3%
270	Polycystic Kidney, Autosomal Dominant	3.3%
271	Menkes Kinky Hair Syndrome	3.3%
272	Tuberous Sclerosis	3.3%
273	Neuronal Ceroid-Lipofuscinoses	3.1%
274	Microcephaly	3%
275	Macrocephaly	3%
276	Refsum Disease	3%
277	Scimitar Syndrome	3%
278	Pseudoxanthoma Elasticum	3%
279	Opsoclonus-Myoclonus Syndrome	3%
280	Myotonic Dystrophy	2.9%
281	Abnormalities, Radiation-Induced	2.9%
282	Craniosynostosis	2.8%
283	Syndactyly	2.8%
284	Brachycephaly	2.8%
285	Charcot-Marie-Tooth Disease	2.8%
286	Antley-Bixler Syndrome Phenotype	2.8%
287	Turner Syndrome	2.8%
288	Laryngostenosis	2.8%
289	Mouth Abnormalities	2.8%
290	Zellweger Syndrome	2.8%
291	Cutis Laxa	2.7%
292	Esophageal Atresia	2.7%
293	Intestinal Atresia	2.7%
294	Horseshoe Kidney	2.7%
295	Pectus excavatum	2.7%
296	Porencephaly	2.7%
297	Klippel-Feil Syndrome	2.7%
298	Gastroschisis	2.7%
299	Synostosis	2.7%
300	Klinefelter Syndrome	2.7%
301	Acrodermatitis	2.7%
302	Lymphangiectasis, Intestinal	2.7%
303	Xeroderma Pigmentosum	2.7%
304	Porokeratosis	2.7%
305	Gianotti-Crosti Syndrome	2.7%
306	Keratoderma, Palmoplantar	2.7%
307	Acrocephalosyndactylia	2.7%
308	Chronic granulomatous disease	2.7%
309	Welander Distal Myopathy	2.7%
310	Miller Fisher Syndrome	2.6%
311	Adrenoleukodystrophy	2.6%
312	Amyloid Neuropathies, Familial	2.6%
313	Hepatolenticular Degeneration	2.5%
314	Amelia	2.5%
315	Arachnodactyly	2.5%
316	Ectopia Cordis	2.5%
317	Ectromelia	2.5%
318	Hemimelia	2.5%
319	Meningomyelocele	2.5%
320	Noonan Syndrome	2.5%
321	Phocomelia	2.5%
322	Sirenomelia	2.5%
323	Spina Bifida	2.5%
324	Polydactyly	2.5%
325	Brachydactyly	2.5%
326	Plagiocephaly	2.5%
327	Lower Extremity Deformities, Congenital	2.5%
328	Upper Extremity Deformities, Congenital	2.5%
329	Single umbilical artery	2.5%
330	Acute Chest Syndrome	2.5%
331	Alkaptonuria	2.5%
332	Glycogen Storage Disease	2.5%
333	Hypophosphatasia	2.5%
334	Propionic acidemia	2.5%
335	Dihydropyrimidine Dehydrogenase Deficiency	2.5%
336	Cystinosis	2.5%
337	Sicca Syndrome	2.5%
338	Sjogren's Syndrome	2.5%
339	Fabry Disease	2.5%
340	Galactosemias	2.5%
341	Urea Cycle Disorders, Inborn	2.5%
342	Tyrosinemias	2.5%
343	Glycogen storage disease type II	2.4%
344	Hydrops Fetalis	2.4%
345	Basal Cell Nevus Syndrome	2.4%
346	Poland Syndrome	2.3%
347	Arthrogryposis	2.3%
348	Choanal Atresia	2.3%
349	Mucopolysaccharidosis III	2.3%
350	Tracheobronchomegaly	2.3%
351	Laryngocele	2.3%
352	Jaw Abnormalities	2.3%
353	Cleft Palate	2.3%
354	Choledochal Cyst	2.3%
355	Hermaphroditism	2.3%
356	Disorders of Sex Development	2.3%
357	Cryptorchidism	2.3%
358	Porphyrias, Hepatic	2.3%
359	Hypospadias	2.3%
360	Ataxia Telangiectasia	2.3%
361	Central Nervous System Cysts	2.3%
362	Dandy-Walker Syndrome	2.2%
363	Peutz-Jeghers Syndrome	2.2%
364	Myotonia Congenita	2.2%
365	Thrombasthenia	2.2%
366	Antithrombin III Deficiency	2.2%
367	Protein C Deficiency	2.2%
368	Brain Diseases, Metabolic, Inborn	2.2%
369	Ophthalmoplegic Migraine	2.2%
370	Afibrinogenemia	2.2%
371	Dystonia Musculorum Deformans	2.2%
372	Factor VII Deficiency	2.2%
373	Factor X Deficiency	2.2%
374	Factor XII Deficiency	2.2%
375	Hemophilia A	2.2%
376	POEMS Syndrome	2.2%
377	Activated Protein C Resistance	2.2%
378	Factor II deficiency	2.2%
379	Factor VIII Deficiency	2.2%
380	Factor V deficiency	2.2%
381	Factor XI Deficiency	2.2%
382	Hypoprothrombinemias	2.2%
383	Fanconi Anemia	2.2%
384	Progressive supranuclear palsy	2.2%
385	Lafora Disease	2.2%
386	Unverricht-Lundborg Syndrome	2.2%
387	Anemia, Diamond-Blackfan	2.2%
388	Hyperphosphaturia	2.2%
389	Canavan Disease	2.1%
390	Alexander Disease	2.1%
391	Dermal Sinus	2.1%
392	Spina Bifida Cystica	2.1%
393	Spina Bifida Occulta	2.1%
394	Lissencephaly	2.1%
395	Polymicrogyria	2.1%
396	Pachygyria	2.1%
397	Schizencephaly	2.1%
398	Periventricular Nodular Heterotopia	2.1%
399	Glycogen Storage Disease Type I	2.1%
400	Glycogen Storage Disease Type V	2.1%
401	Aortic coarctation	2%
402	Cor Triatriatum	2%
403	Coronary Vessel Anomalies	2%
404	Dental Enamel Hypoplasia	2%
405	Patent ductus arteriosus	2%
406	Ebstein Anomaly	2%
407	Heart Septal Defects	2%
408	Hypodontia	2%
409	Macrostomia	2%
410	Meningocele	2%
411	Microstomia	2%
412	Tetralogy of Fallot	2%
413	Transposition of Great Vessels	2%
414	Hypoplastic Left Heart Syndrome	2%
415	May-Thurner Syndrome	2%
416	Encephalocele	2%
417	Homocystinuria	2%
418	Craniofacial Dysostosis	2%
419	Leigh Disease	2%
420	Hypolipoproteinemias	2%
421	Papillon-Lefevre Disease	2%
422	Wolff-Parkinson-White Syndrome	2%
423	Hyperlipidemia, Familial Combined	2%
424	Multiple Endocrine Neoplasia	2%
425	Laryngomalacia	2%
426	Hyperlipoproteinemia Type III	2%
427	Neuromyelitis Optica	2%
428	Gaucher Disease	2%
429	Pectus carinatum	2%
430	Micrognathism	1.9%
431	Pierre Robin Syndrome	1.9%
432	Bladder Exstrophy	1.9%
433	Congenital Hypothyroidism	1.9%
434	Epispadias	1.9%
435	Dermatitis, Atopic	1.9%
436	Multicystic Dysplastic Kidney	1.9%
437	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.8%
438	Tay-Sachs Disease	1.8%
439	Retrognathia	1.7%
440	Niemann-Pick Disease, Type C	1.7%
441	Familial Periodic Paralysis	1.7%
442	Long QT Syndrome	1.7%
443	Platybasia	1.7%
444	Tricuspid Atresia	1.7%
445	Arrhythmogenic Right Ventricular Dysplasia	1.7%
446	Gonadal Dysgenesis	1.7%
447	Bronchomalacia	1.7%
448	Adrenogenital Syndrome	1.7%
449	Tracheomalacia	1.7%
450	Ovotesticular Disorders of Sex Development	1.7%
451	Lactose Intolerance	1.7%
452	Variegate Porphyria	1.7%
453	Acute intermittent porphyria	1.7%
454	Porphyria Cutanea Tarda	1.7%
455	Hyperhomocysteinemia	1.7%
456	Aortopulmonary Septal Defect	1.7%
457	Double Outlet Right Ventricle	1.7%
458	Endocardial Cushion Defects	1.7%
459	Myocardial bridging	1.7%
460	Aorticopulmonary Septal Defect	1.7%
461	Renal Aminoacidurias	1.6%
462	Fanconi Syndrome	1.6%
463	Pseudohypoaldosteronism	1.6%
464	Liddle Syndrome	1.6%
465	Hypoalphalipoproteinemias	1.6%
466	Hyperlipoproteinemia Type IV	1.6%
467	Hyperlipoproteinemia Type V	1.6%
468	Hyperandrogenism	1.6%
469	Optic Nerve Glioma	1.6%
470	Prognathism	1.6%
471	Huntington Disease	1.5%
472	Truncus Arteriosus, Persistent	1.5%
473	Goldenhar Syndrome	1.5%
474	Gout	1.4%
475	Multiple Endocrine Neoplasia Type 1	1.4%
476	Pseudohypoparathyroidism	1.4%
477	Friedreich Ataxia	1.4%
478	Renal tubular acidosis	1.4%
479	Hypokalemic periodic paralysis	1.4%
480	Romano-Ward Syndrome	1.4%
481	Cystinuria	1.4%
482	Nephroblastoma	1.3%
483	Denys-Drash Syndrome	1.3%
484	Talipes	1.2%
485	Adenomatous Polyposis Coli	1.2%
486	Arthritis, Gouty	1.2%
487	Congenital clubfoot	1.2%
488	Vertical Talus	1.2%
489	Familial Hypophosphatemic Rickets	1.1%
490	Glycosuria, Renal	1.1%
491	Arteriovenous fistula	1%
492	MELAS Syndrome	0.9%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234