MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Biliary Dyskinesia

(UMLS:C0005416)

Definition:: A motility disorder characterized by biliary COLIC, absence of GALLSTONES, and an abnormal GALLBLADDER ejection fraction. It is caused by gallbladder dyskinesia and/or SPHINCTER OF ODDI DYSFUNCTION.
UMLS ID:: C0005416
MeSH ID:: D001657

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.130.120.250.098

Synonym(s)

Biliary Dyskinesia

BILIARY DYSKINESIA

Biliary dyskinesia

biliary dyskinesia

biliary dyskinesias

biliary; dyskinesia

dyskinesia biliary

dyskinesia; biliary

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Isotretinoin	FAERS: 21		US FAERS
2	Estradiol	FAERS: 5	20337216	CTD US FAERS
3	Benicar hct	FAERS: 4		US FAERS
4	Olmesartan Medoxomil	FAERS: 4		US FAERS
5	rofecoxib	FAERS: 4		US FAERS
6	Exenatide	FAERS: 3		US FAERS
7	tegaserod	FAERS: 3		OFFSIDES US FAERS
8	Fenofibrate	FAERS: 2		US FAERS
9	Ketamine	FAERS: 2		US FAERS
10	Liraglutide	FAERS: 2		US FAERS
11	Metoclopramide	FAERS: 2		US FAERS
12	Teriparatide	FAERS: 2		US FAERS
13	Valproic Acid	FAERS: 2		US FAERS
14	candesartan cilexetil	FAERS: 2		US FAERS
15	drospirenone and ethinyl estradiol combination	FAERS: 2		US FAERS
16	zolmitriptan	FAERS: 2		US FAERS
17	4-hydroxybutyric acid	FAERS: 1		US FAERS
18	Amlodipine	FAERS: 1		US FAERS
19	Atorvastatin	FAERS: 1		US FAERS
20	Fentanyl	FAERS: 1		US FAERS
21	Lenalidomide	FAERS: 1		US FAERS
22	Omeprazole	FAERS: 1		US FAERS
23	Ortho Evra	FAERS: 1		US FAERS
24	Rosuvastatin Calcium	FAERS: 1		US FAERS
25	acetaminophen, aspirin, caffeine drug combination	FAERS: 1		US FAERS
26	bicalutamide	FAERS: 1		US FAERS
27	nintedanib	FAERS: 1		US FAERS
28	ponatinib	FAERS: 1		US FAERS
29	Acyclovir			OFFSIDES
30	Adapalene			OFFSIDES
31	Atropine			OFFSIDES
32	Azithromycin			OFFSIDES
33	Biotin			OFFSIDES
34	Bupropion			OFFSIDES
35	Buspirone			OFFSIDES
36	Carisoprodol			OFFSIDES
37	Clonazepam			OFFSIDES
38	Colestipol			OFFSIDES
39	Dextropropoxyphene			OFFSIDES
40	Dicyclomine			OFFSIDES
41	Doxycycline			OFFSIDES
42	Dronabinol			OFFSIDES
43	Epinephrine			OFFSIDES
44	Fluticasone-Salmeterol Drug Combination			OFFSIDES
45	Glipizide			OFFSIDES
46	Ibuprofen			OFFSIDES
47	Isoniazid			OFFSIDES
48	Lithium Carbonate			OFFSIDES
49	Loratadine			OFFSIDES
50	Midazolam			OFFSIDES
51	Nizatidine			OFFSIDES
52	Orlistat			OFFSIDES
53	Orphenadrine			OFFSIDES
54	Oxcarbazepine			OFFSIDES
55	Perindopril			OFFSIDES
56	Phentermine			OFFSIDES
57	Promethazine			OFFSIDES
58	Pyridoxine			OFFSIDES
59	Quinidine			OFFSIDES
60	Rabeprazole			OFFSIDES
61	Ribavirin			OFFSIDES
62	Sulfamethoxazole			OFFSIDES
63	Sumatriptan			OFFSIDES
64	Thiothixene			OFFSIDES
65	Tolterodine Tartrate			OFFSIDES
66	Topiramate			OFFSIDES
67	Trazodone			OFFSIDES
68	Tretinoin			OFFSIDES
69	Valacyclovir			OFFSIDES
70	Vitamin B 12			OFFSIDES
71	cefprozil			OFFSIDES
72	cyclobenzaprine			OFFSIDES
73	dolasetron			OFFSIDES
74	eletriptan			OFFSIDES
75	moexipril			OFFSIDES
76	naratriptan			OFFSIDES
77	norgestimate, ethinyl estradiol drug combination			OFFSIDES
78	tegaserod			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Choledocholithiasis	42.4%
2	Cholangitis	34.4%
3	Cholestasis	34.4%
4	Cholelithiasis	25.4%
5	Cholestasis, Extrahepatic	22.6%
6	Cholangitis, Sclerosing	22.6%
7	Bile Duct Neoplasms	21.7%
8	Cholecystolithiasis	19.8%
9	Choledochal Cyst	17.7%
10	Gastrointestinal Diseases	16.4%
11	Liver diseases	16.4%
12	Pancreatic Diseases	16.4%
13	Cholecystitis	14.8%
14	gallbladder neoplasm	13.8%
15	Biliary cirrhosis	13.5%
16	Digestive System Neoplasms	10.8%
17	Acalculous Cholecystitis	9.7%
18	Gastrointestinal Neoplasms	8.5%
19	Liver neoplasms	8.5%
20	Chylous Ascites	8.5%
21	Esophageal Diseases	8.5%
22	Fatty Liver	8.5%
23	Gastroenteritis	8.5%
24	Hepatitis	8.5%
25	Portal Hypertension	8.5%
26	Intestinal Diseases	8.5%
27	Liver Cirrhosis	8.5%
28	Pancreatic Fistula	8.5%
29	Pancreatic Insufficiency	8.5%
30	Pancreatitis	8.5%
31	Pneumoperitoneum	8.5%
32	Stomach Diseases	8.5%
33	Focal Nodular Hyperplasia	8.5%
34	Hepatic Insufficiency	8.5%
35	Steatohepatitis	8.5%
36	Emphysematous Cholecystitis	7.2%
37	Mesenteric vascular insufficiency	6.8%
38	Peritoneal Neoplasms	6.8%
39	Esophageal Atresia	6.7%
40	Intestinal Atresia	6.7%
41	Mesenteric Vascular Occlusion	6.7%
42	Intestinal Fistula	6.7%
43	Enterocutaneous Fistula	6.7%
44	Dysentery	6.6%
45	Enteritis	6.6%
46	Enterocolitis	6.6%
47	Esophageal and Gastric Varices	6.6%
48	Esophagitis	6.6%
49	Gastritis	6.6%
50	Inflammatory Bowel Diseases	6.6%
51	Zollinger-Ellison syndrome	6.4%
52	Liver Diseases, Parasitic	6%
53	Intestinal Neoplasms	5.9%
54	Stomach Neoplasms	5.9%
55	Hepatic Veno-Occlusive Disease	5.7%
56	Pancreatic Cyst	5.7%
57	Peliosis Hepatis	5.7%
58	Hepatopulmonary Syndrome	5.7%
59	Pancreatic Neoplasm	5.7%
60	Anus, Imperforate	5.6%
61	Gastrointestinal Hemorrhage	5.6%
62	Hemoperitoneum	5.6%
63	Hepatomegaly	5.6%
64	Mesenteric Panniculitis	5.6%
65	Panniculitis, Peritoneal	5.6%
66	Peritonitis	5.6%
67	Peritoneal Fibrosis	5.6%
68	Encapsulating Peritoneal Sclerosis	5.6%
69	Anorectal Malformations	5.6%
70	Biliary Fistula	5.6%
71	Gastric Fistula	5.6%
72	Hepatic Vein Thrombosis	5.5%
73	Liver Abscess	5.5%
74	Budd-Chiari Syndrome	5.5%
75	Tuberculosis, Gastrointestinal	5.5%
76	Colitis	5.4%
77	Duodenogastric Reflux	5.4%
78	Peptic Ulcer	5.4%
79	Proctitis	5.4%
80	Esophageal Neoplasms	4.9%
81	Cecal Diseases	4.9%
82	Colonic Diseases	4.9%
83	Esophageal Stenosis	4.9%
84	Hepatitis, Chronic	4.9%
85	Ileal Diseases	4.9%
86	Intestinal Obstruction	4.9%
87	Intestinal Perforation	4.9%
88	Jejunal Diseases	4.9%
89	Pneumatosis Cystoides Intestinalis	4.9%
90	Rectal Diseases	4.9%
91	Gastric Dilatation	4.9%
92	Liver Failure	4.9%
93	Pancreatitis, Chronic	4.9%
94	Gastric outlet obstruction	4.9%
95	Gastrointestinal Stromal Tumors	4.9%
96	Cronkhite-Canada Syndrome	4.9%
97	Non-alcoholic Fatty Liver Disease	4.9%
98	Chronic active hepatitis	4.9%
99	Intestinal Polyposis	4.9%
100	Fatty Liver, Alcoholic	4.9%
101	Hepatitis, Alcoholic	4.9%
102	Liver Cirrhosis, Alcoholic	4.9%
103	Duodenitis	4.8%
104	Ileitis	4.8%
105	Erosive Duodenitis	4.8%
106	Colorectal Neoplasms	4.6%
107	Proctocolitis	4.5%
108	Rectal Fistula	4.5%
109	Anal Fistula	4.5%
110	Chemical and Drug Induced Liver Injury	4.3%
111	Crohn Disease	4.3%
112	Duodenal Obstruction	4.3%
113	Enterocolitis, Neutropenic	4.3%
114	Necrotizing Enterocolitis	4.3%
115	Cecal Neoplasms	4.3%
116	Duodenal Neoplasms	4.3%
117	Hepatorenal Syndrome	4.2%
118	Appendicitis	4.1%
119	Hepatocellular Adenoma	3.9%
120	Duodenal Ulcer	3.7%
121	Peptic Ulcer Perforation	3.7%
122	Gastric ulcer	3.7%
123	Pouchitis	3.6%
124	Esophageal Perforation	3.5%
125	Hepatitis, Animal	3.5%
126	Hepatitis, Viral, Human	3.5%
127	Intestinal Diseases, Parasitic	3.5%
128	Cystic Fibrosis	3.5%
129	Barrett Esophagus	3.4%
130	Deglutition Disorders	3.4%
131	Porphyrias, Hepatic	3.4%
132	Congenital Hyperinsulinism	3.4%
133	Liver Abscess, Amebic	3.3%
134	Liver Neoplasms, Experimental	3.3%
135	Achlorhydria	3.3%
136	Liver Cirrhosis, Experimental	3.3%
137	Pancreatic Pseudocyst	3.3%
138	Gastric Antral Vascular Ectasia	3.3%
139	Peptic Ulcer Hemorrhage	3.3%
140	Gastroparesis	3.3%
141	Pancreatitis, Alcoholic	3.3%
142	Colonic Diseases, Functional	3.2%
143	Enterocolitis, Pseudomembranous	3.2%
144	Esophageal motility disorders	3.2%
145	Fecal Incontinence	3.2%
146	Fecal Impaction	3.2%
147	Intussusception	3.2%
148	Mallory-Weiss Syndrome	3.2%
149	Megacolon	3.2%
150	Pyloric Stenosis	3.2%
151	Liver Failure, Acute	3.2%
152	End Stage Liver Disease	3.2%
153	pseudomembranous colitis	3.2%
154	Ileus	3.2%
155	Dysentery, Bacillary	3.2%
156	Meconium ileus	3.2%
157	Appendiceal Neoplasms	3.2%
158	Colonic Neoplasms	3.2%
159	Rectal Neoplasms	3.2%
160	Anus Neoplasms	2.9%
161	Sigmoid Neoplasms	2.9%
162	Colonic Pseudo-Obstruction	2.9%
163	Colitis, Ischemic	2.9%
164	Adenomatous Polyposis Coli	2.6%
165	Fascioliasis	2.5%
166	Echinococcosis, Hepatic	2.5%
167	Melena	2.5%
168	Chemical and Drug Induced Liver Injury, Chronic	2.5%
169	Reye Syndrome	2.5%
170	Hematemesis	2.4%
171	Carcinoma, Pancreatic Ductal	2.4%
172	Massive Hepatic Necrosis	2.4%
173	Esophageal Achalasia	2.4%
174	Anal Fissure	2.4%
175	Intestinal Pseudo-Obstruction	2.4%
176	Irritable Bowel Syndrome	2.4%
177	Superior Mesenteric Artery Syndrome	2.4%
178	Neurogenic Bowel	2.4%
179	Anal Ulcer	2.4%
180	Hepatitis B, Chronic	2.3%
181	Hepatitis C, Chronic	2.3%
182	Hemorrhoids	2.2%
183	Autoimmune hepatitis	2.2%
184	Afferent Loop Syndrome	2.2%
185	Celiac Disease	2.2%
186	Short Bowel Syndrome	2.2%
187	Sprue, Tropical	2.2%
188	Steatorrhea	2.2%
189	Rectocele	2.2%
190	Sprue	2.2%
191	Diverticulitis	2.2%
192	Dumping Syndrome	2.2%
193	Rectal Prolapse	2.2%
194	Nesidioblastosis	1.9%
195	Variegate Porphyria	1.9%
196	Acute intermittent porphyria	1.9%
197	Porphyria Cutanea Tarda	1.9%
198	insulinoma	1.8%
199	Gastrinoma	1.8%
200	Glucagonoma	1.8%
201	Hepatitis, Viral, Animal	1.8%
202	Giardiasis	1.7%
203	Hepatitis E	1.7%
204	Hepatitis B	1.7%
205	Hepatitis C	1.7%
206	Diverticulum	1.7%
207	Hepatitis A	1.7%
208	Diverticulosis	1.7%
209	Hepatic Encephalopathy	1.6%
210	Pruritus Ani	1.6%
211	Vipoma	1.6%
212	Zellweger Syndrome	1.5%
213	Laryngopharyngeal Reflux	1.4%
214	Hepatolenticular Degeneration	1.4%
215	Peutz-Jeghers Syndrome	1.3%
216	Lactose Intolerance	1.3%
217	Cryptosporidiosis	1%
218	Rift Valley Fever	0.7%
219	CREST Syndrome	0.7%

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