MetaADEDB 2.0 @ LMMD
Salmeterol Xinafoate
(XTZNCVSCVHTPAI-UHFFFAOYSA-N)
Structure
SMILES
OC(=O)c1ccc2c(c1O)cccc2.OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O
Molecular Formula:
C36H45NO7
Molecular Weight:
603.745
Log P:
6.7419
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
6
TPSA:
139.48
CAS Number(s):
94749-08-3
Synonym(s)
1.
Salmeterol Xinafoate
2.
Salmeterol
3.
Serevent
4.
Xinafoate, Salmeterol
External Link(s)
MeSHD000068299
PubChem Compound54687251
56801
ChEBI9012
CHEMBLCHEMBL1082607
KEGGdr:D00687
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 41
Canada Vigilance: 13		Canada Vigilance
OFFSIDES
US FAERS
2Device use errorFAERS: 35US FAERS
3Drug dose omissionFAERS: 28US FAERS
4Product quality issueFAERS: 26
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
5Wrong technique in product usage processFAERS: 17US FAERS
6MalaiseFAERS: 13US FAERS
7Product complaintFAERS: 13
Canada Vigilance: 3		Canada Vigilance
US FAERS
8Wrong technique in device usage processFAERS: 13US FAERS
9Product dose omissionFAERS: 10US FAERS
10AsthmaFAERS: 9
Canada Vigilance: 4

View details

1687131
9164358
9385125
9707465
9731027
10359889
10480584
11449530
11694805
12166584
12449667
15025036
16973987
22607479
 		CTD
OFFSIDES
Canada Vigilance
US FAERS
11Intentional product misuseFAERS: 7US FAERS
12OverdoseFAERS: 7US FAERS
13Drug dispensing errorFAERS: 6US FAERS
14Extra dose administeredFAERS: 5US FAERS
15Medication ErrorFAERS: 5US FAERS
16PneumoniaFAERS: 5US FAERS
17BronchitisFAERS: 423548184CTD
OFFSIDES
US FAERS
18Chest discomfortFAERS: 4US FAERS
19DysphoniaFAERS: 4OFFSIDES
US FAERS
20HeadacheFAERS: 41349491
10516540		CTD
US FAERS
21Inappropriate schedule of drug administrationFAERS: 4US FAERS
22Intentional product use issueFAERS: 4US FAERS
23Myocardial InfarctionFAERS: 4US FAERS
24NasopharyngitisFAERS: 4OFFSIDES
US FAERS
25Chest PainFAERS: 3OFFSIDES
US FAERS
26Complication associated with deviceFAERS: 3US FAERS
27CystitisFAERS: 3US FAERS
28Expired product administeredFAERS: 3US FAERS
29Multiple allergiesFAERS: 3US FAERS
30NephrolithiasisFAERS: 3US FAERS
31Prescribed underdoseFAERS: 3US FAERS
32Product use in unapproved indicationFAERS: 3US FAERS
33Sensitivity to weather changeFAERS: 3US FAERS
34WheezingFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
35Accidental overdoseFAERS: 2US FAERS
36Adverse eventFAERS: 2OFFSIDES
US FAERS
37Circumstance or information capable of leading to medication errorFAERS: 2US FAERS
38DizzinessFAERS: 2US FAERS
39EczemaFAERS: 2US FAERS
40Inability to afford medicationFAERS: 2US FAERS
41Inappropriate schedule of product administrationFAERS: 2US FAERS
42Joint swellingFAERS: 2US FAERS
43Memory impairmentFAERS: 2US FAERS
44Mouth swellingFAERS: 2US FAERS
45Muscle tightnessFAERS: 2US FAERS
46NervousnessFAERS: 2US FAERS
47Oral painFAERS: 2US FAERS
48Product label confusionFAERS: 2US FAERS
49Product use issueFAERS: 2US FAERS
50Respiratory FailureFAERS: 2OFFSIDES
US FAERS
51StomatitisFAERS: 2US FAERS
52Abdominal discomfortFAERS: 1OFFSIDES
US FAERS
53AnosmiaFAERS: 1OFFSIDES
US FAERS
54AnxietyFAERS: 1OFFSIDES
US FAERS
55ArthralgiaFAERS: 1US FAERS
56ArthritisFAERS: 1US FAERS
57Atypical pneumoniaFAERS: 1US FAERS
58BlindnessFAERS: 1US FAERS
59Blood glucose abnormalFAERS: 1US FAERS
60Blood potassium decreasedFAERS: 1US FAERS
61Buccal mucosal rougheningFAERS: 1US FAERS
62Cataract operationFAERS: 1US FAERS
63CheilitisFAERS: 1US FAERS
64ConvalescentFAERS: 1US FAERS
65DementiaFAERS: 1US FAERS
66Dermatitis acneiformFAERS: 1US FAERS
67Device use issueFAERS: 1US FAERS
68DiverticulitisFAERS: 1OFFSIDES
US FAERS
69Drug prescribing errorFAERS: 1US FAERS
70DysgeusiaFAERS: 1
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
71Electrolyte depletionFAERS: 1US FAERS
72Failure to ThriveFAERS: 1US FAERS
73FatigueFAERS: 1US FAERS
74Feeling abnormalFAERS: 1US FAERS
75FractureFAERS: 1US FAERS
76GlaucomaFAERS: 1US FAERS
77Gluten sensitivityFAERS: 1US FAERS
78Hospice CareFAERS: 1US FAERS
79HypersensitivityFAERS: 1US FAERS
80Incorrect dose administeredFAERS: 1US FAERS
81Incorrect product storageFAERS: 1US FAERS
82Infective exacerbation of chronic obstructive airways diseaseFAERS: 1US FAERS
83Inhalation TherapyFAERS: 1OFFSIDES
US FAERS
84Intentional device use issueFAERS: 1US FAERS
85Intercepted drug administration errorFAERS: 1US FAERS
86Intestinal resectionFAERS: 1US FAERS
87Lip swellingFAERS: 1US FAERS
88Live BirthFAERS: 1US FAERS
89Medical device discomfortFAERS: 1US FAERS
90Metabolic acidosisFAERS: 1US FAERS
91MetastasisFAERS: 1US FAERS
92NauseaFAERS: 1US FAERS
93Oropharyngeal painFAERS: 1US FAERS
94Oxygen supplementationFAERS: 1US FAERS
95PainFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
96PalpitationsFAERS: 1US FAERS
97PneumothoraxFAERS: 1OFFSIDES
US FAERS
98Poor quality device usedFAERS: 1US FAERS
99Prescribed overdoseFAERS: 1US FAERS
100Product formulation issueFAERS: 1US FAERS
101Product preparation errorFAERS: 1US FAERS
102Product storage errorFAERS: 1US FAERS
103Product taste abnormalFAERS: 1US FAERS
104Productive CoughFAERS: 1OFFSIDES
US FAERS
105PruritusFAERS: 1US FAERS
106Pulmonary painFAERS: 1US FAERS
107Rash erythematousFAERS: 1US FAERS
108Rheumatoid ArthritisFAERS: 1US FAERS
109Sinus TachycardiaFAERS: 1US FAERS
110Sinus painFAERS: 1US FAERS
111SinusitisFAERS: 1OFFSIDES
US FAERS
112SomnolenceFAERS: 1US FAERS
113Therapeutic response unexpectedFAERS: 1US FAERS
114Throat cancerFAERS: 1US FAERS
115Throat irritationFAERS: 1US FAERS
116Toxicity to various agentsFAERS: 1US FAERS
117TremorFAERS: 1

View details

1349491
1687131
9707465
10516540
 		CTD
US FAERS
118Uterine CancerFAERS: 1OFFSIDES
US FAERS
119Uterine contractions during pregnancyFAERS: 1US FAERS
120Visual ImpairmentFAERS: 1US FAERS
121VomitingFAERS: 1US FAERS
122Weight decreasedFAERS: 1US FAERS
123Wrong patient received medicationFAERS: 1US FAERS
124ACTH stimulation test abnormalOFFSIDES
125Abdominal InfectionOFFSIDES
126Abdominal adhesionsOFFSIDES
127Abdominal tendernessOFFSIDES
128Abnormal cervical smearOFFSIDES
129Abnormal sleep-related eventOFFSIDES
130AbscessOFFSIDES
131Acute Coronary SyndromeOFFSIDES
132Acute bronchitisOFFSIDES
133Acute otitis mediaOFFSIDES
134Acute prerenal failureOFFSIDES
135Acute respiratory failureOFFSIDES
136Acute sinusitisOFFSIDES
137AdrenalitisOFFSIDES
138AgeusiaOFFSIDES
139Agonal death struggleOFFSIDES
140AgoraphobiaOFFSIDES
141Alcohol problemOFFSIDES
142AmenorrheaOFFSIDES
143Amniotic fluid volume decreasedOFFSIDES
144AmyloidosisOFFSIDES
145Anal abscessOFFSIDES
146Anal inflammationOFFSIDES
147Anemia9434678CTD
148Angioedema10982225CTD
149Angle Closure GlaucomaOFFSIDES
150AnhedoniaOFFSIDES
151Anoxic EncephalopathyOFFSIDES
152Antigliadin antibody positiveOFFSIDES
153Antimicrobial susceptibility test resistantOFFSIDES
154Aortic valve calcificationOFFSIDES
155AphoniaOFFSIDES
156AsphyxiaOFFSIDES
157Asthma, Exercise-Induced10984370CTD
158AtelectasisOFFSIDES
159Atrial pressure increasedOFFSIDES
160Atrophic vulvovaginitisOFFSIDES
161Avascular necrosisOFFSIDES
162Axillary vein thrombosisOFFSIDES
163Bacterial rhinitisOFFSIDES
164Bipolar DisorderOFFSIDES
165Bladder spasmOFFSIDES
166Bladder tamponadeOFFSIDES
167Blighted ovumOFFSIDES
168Blood corticotrophinOFFSIDES
169Blood cortisol decreasedOFFSIDES
170Blood creatine phosphokinase MM increasedOFFSIDES
171Blood ethanol increasedOFFSIDES
172Blood gases abnormalOFFSIDES
173Blood growth hormone decreasedOFFSIDES
174Blood immunoglobulin G decreasedOFFSIDES
175Blood lactate dehydrogenaseOFFSIDES
176Blood magnesium increasedOFFSIDES
177Blood pH decreasedOFFSIDES
178Blood phosphorus increasedOFFSIDES
179Blood pressure immeasurableOFFSIDES
180Bone callus excessiveOFFSIDES
181Bone fistulaOFFSIDES
182Bone lesionOFFSIDES
183Bone painOFFSIDES
184Brain DeathOFFSIDES
185Brain HypoxiaOFFSIDES
186Breech PresentationOFFSIDES
187Bronchial ObstructionOFFSIDES
188Bronchial irritationOFFSIDES
189Bronchial secretion retentionOFFSIDES
190BronchiectasisOFFSIDES
191Bronchitis, Chronic17687719CTD
192Bronchoalveolar LavageOFFSIDES
193Bronchopleural FistulaOFFSIDES
194Bullous lung diseaseOFFSIDES
195BursitisOFFSIDES
196CalcinosisOFFSIDES
197Cardiac DeathOFFSIDES
198Cardiac asthmaOFFSIDES
199Cardiac infectionOFFSIDES
200Catheter related infectionOFFSIDES
201Catheter site inflammationOFFSIDES
202Catheter site painOFFSIDES
203Cervicobrachial syndromeOFFSIDES
204Chemical injuryOFFSIDES
205Chest wall painOFFSIDES
206Choking sensationOFFSIDES
207ChondromalaciaOFFSIDES
208Chronic Obstructive Airway DiseaseOFFSIDES
209Chronic sinusitisOFFSIDES
210ClaustrophobiaOFFSIDES
211Cleft PalateOFFSIDES
212Clostridium colitisOFFSIDES
213Cold sweatOFFSIDES
214ColitisOFFSIDES
215Colon adenomaOFFSIDES
216Complications of maternal exposure to therapeutic drugsOFFSIDES
217Compression fractureOFFSIDES
218Cor pulmonaleOFFSIDES
219Croup infectiousOFFSIDES
220CyanosisOFFSIDES
221CystoceleOFFSIDES
222CystOFFSIDES
223Delusional disorder, unspecified typeOFFSIDES
224Dental discomfortOFFSIDES
225Dental prosthesis userOFFSIDES
226Denture wearerOFFSIDES
227Depressed moodOFFSIDES
228Device ineffectiveOFFSIDES
229Device malfunctionCanada Vigilance: 1Canada Vigilance
230Diabetic foot infectionOFFSIDES
231Diabetic ulcerOFFSIDES
232Diffuse panbronchiolitisOFFSIDES
233DiverticulosisOFFSIDES
234Drug ToleranceOFFSIDES
235Drug addictOFFSIDES
236Drug exposure during pregnancyOFFSIDES
237Drug withdrawal headacheOFFSIDES
238DysgraphiaOFFSIDES
239DyspepsiaCanada Vigilance: 1Canada Vigilance
240Dyspnoea exacerbatedOFFSIDES
241DysuriaOFFSIDES
242Economic problemOFFSIDES
243Edema8899116CTD
244Electrocardiogram ST-T segment abnormalOFFSIDES
245Electromechanical dissociationOFFSIDES
246Embolic strokeOFFSIDES
247Emotional distressOFFSIDES
248Endodontic procedureOFFSIDES
249EnophthalmosOFFSIDES
250Enterovesical FistulaOFFSIDES
251Enuresis8649105CTD
OFFSIDES
252Eosinophilic PneumoniaOFFSIDES
253Epstein-Barr virus associated lymphoproliferative disorderOFFSIDES
254Erythema NodosumOFFSIDES
255Esophageal StenosisOFFSIDES
256Eustachian tube disorderOFFSIDES
257Expired drug administeredOFFSIDES
258Exposure to allergenOFFSIDES
259Exposure to toxic agentOFFSIDES
260Eye InfectionOFFSIDES
261Eye RednessOFFSIDES
262Eyelid margin crustingOFFSIDES
263Facial NeuralgiaOFFSIDES
264Factor V deficiencyOFFSIDES
265Factor XI DeficiencyOFFSIDES
266Femoral pulseOFFSIDES
267Flank PainOFFSIDES
268Foreign body aspirationOFFSIDES
269Gastric infectionOFFSIDES
270Gastrointestinal tract adenomaOFFSIDES
271Gestational DiabetesOFFSIDES
272Gingival HyperplasiaOFFSIDES
273GingivectomyOFFSIDES
274GoiterOFFSIDES
275GranulomaOFFSIDES
276Hepatojugular refluxOFFSIDES
277HiccoughOFFSIDES
278Hilar lymphadenopathyOFFSIDES
279Histamine level increasedOFFSIDES
280HoarsenessOFFSIDES
281HydrocephalusOFFSIDES
282Hypertrophy20219844CTD
283HypometabolismOFFSIDES
284HyporeflexiaOFFSIDES
285HypoxiaOFFSIDES
286IleitisOFFSIDES
287Increased upper airway secretionOFFSIDES
288Increased viscosity of bronchial secretionOFFSIDES
289Infective tenosynovitisOFFSIDES
290Inflammation12823118CTD
291Infusion site bruisingOFFSIDES
292Infusion site rashOFFSIDES
293Injection site burningOFFSIDES
294Injection site erythemaOFFSIDES
295Injection site inflammationOFFSIDES
296Injection site stingingOFFSIDES
297Insulin tolerance test abnormalOFFSIDES
298Intention tremorOFFSIDES
299Intentional device misuseCanada Vigilance: 1Canada Vigilance
300Joint sprainOFFSIDES
301Jugular vein distensionOFFSIDES
302Klebsiella sepsisOFFSIDES
303Laboratory test interferenceOFFSIDES
304LacerationOFFSIDES
305Lactose IntoleranceOFFSIDES
306Latex allergyOFFSIDES
307Left ventricular end-diastolic pressure decreasedOFFSIDES
308Life expectancy shortenedOFFSIDES
309Listeria sepsisOFFSIDES
310Liver AbscessOFFSIDES
311Local reactionOFFSIDES
312Lumbar radiculopathyOFFSIDES
313Lung hyperinflationOFFSIDES
314Lysosomal Storage Diseases28551711CTD
315Malignant tumour excisionOFFSIDES
316Mastication disorderOFFSIDES
317Maxillofacial operationOFFSIDES
318Mediastinal massOFFSIDES
319Medical device complicationOFFSIDES
320Metastatic NeoplasmOFFSIDES
321Middle insomniaOFFSIDES
322Migraine with AuraOFFSIDES
323Monoclonal immunoglobulin presentOFFSIDES
324MorpheaOFFSIDES
325Mucosal erosionOFFSIDES
326Multiple drug overdoseOFFSIDES
327Muscle flap operationOFFSIDES
328Muscle hypertrophyOFFSIDES
329Musculoskeletal chest painCanada Vigilance: 1Canada Vigilance
330Musculoskeletal discomfortOFFSIDES
331Musculoskeletal stiffnessOFFSIDES
332Myasthenia GravisOFFSIDES
333Nasal discomfortOFFSIDES
334Nasal sinus drainageOFFSIDES
335Nephrotic SyndromeOFFSIDES
336Nerve BlockOFFSIDES
337Nerve Root CompressionOFFSIDES
338Nervous tensionOFFSIDES
339NeuroglycopeniaOFFSIDES
340Neuroleptic Malignant SyndromeOFFSIDES
341NeuromaOFFSIDES
342Neuropathic painOFFSIDES
343Nodal osteoarthritisOFFSIDES
344Nonspecific reactionOFFSIDES
345Occult blood positiveOFFSIDES
346OphthalmoplegiaOFFSIDES
347Optic AtrophyOFFSIDES
348Optic Disc EdemaOFFSIDES
349Optic NeuritisOFFSIDES
350Oral dischargeOFFSIDES
351Oral fungal infectionOFFSIDES
352Oral infectionOFFSIDES
353Oral polypectomyOFFSIDES
354Oropharyngeal candidiasisOFFSIDES
355Oropharyngeal swellingOFFSIDES
356Oropharyngitis fungalOFFSIDES
357OsteopeniaOFFSIDES
358OsteoporosisOFFSIDES
359OverweightOFFSIDES
360PO2 decreasedOFFSIDES
361Pain of skinOFFSIDES
362Palliative CareOFFSIDES
363Pancreatic enzymes abnormalOFFSIDES
364Paranasal sinus discomfortOFFSIDES
365ParanoiaOFFSIDES
366PeriodontitisOFFSIDES
367Pharmaceutical product complaintOFFSIDES
368Pharyngolaryngeal PainOFFSIDES
369Pilonidal CystOFFSIDES
370PlagiocephalyOFFSIDES
371PneumoconiosisOFFSIDES
372PolydactylyOFFSIDES
373Poor personal hygieneOFFSIDES
374Poor quality drug administeredOFFSIDES
375Postoperative adhesionOFFSIDES
376Postoperative constipationOFFSIDES
377Product residue presentCanada Vigilance: 1Canada Vigilance
378Progesterone receptor assayOFFSIDES
379PseudarthrosisOFFSIDES
380Psychiatric decompensationOFFSIDES
381Pulmonary HypertensionOFFSIDES
382Pulmonary function test decreasedOFFSIDES
383RadiculitisOFFSIDES
384Rectal polypOFFSIDES
385Respiratory TherapyOFFSIDES
386Respiratory tract congestionOFFSIDES
387Respiratory tract irritationOFFSIDES
388Retinal DegenerationOFFSIDES
389RetrocollisOFFSIDES
390RhinitisOFFSIDES
391RhinorrheaOFFSIDES
392RhonchiOFFSIDES
393Right atrial dilatationOFFSIDES
394Right ventricular systolic pressure decreasedOFFSIDES
395Risus sardonicusOFFSIDES
396SchizophreniaOFFSIDES
397SclerodermaOFFSIDES
398Sensory level abnormalOFFSIDES
399SequestrectomyOFFSIDES
400SigmoiditisOFFSIDES
401Skin lacerationOFFSIDES
402Skin lesionOFFSIDES
403Skull X-ray abnormalOFFSIDES
404Smooth Muscle Tumor20219844CTD
405Sputum culture positiveOFFSIDES
406Sputum retentionOFFSIDES
407StaringOFFSIDES
408Status EpilepticusOFFSIDES
409SubileusOFFSIDES
410Sudden deathOFFSIDES
411Suture insertionOFFSIDES
412SyndactylyOFFSIDES
413T-cell lymphoma recurrentOFFSIDES
414Tachycardia20219844CTD
415Tarsal Tunnel SyndromeOFFSIDES
416Therapy non-responderOFFSIDES
417ThoracotomyOFFSIDES
418Tinea PedisOFFSIDES
419Tinea VersicolorOFFSIDES
420Tinea crurisOFFSIDES
421Tongue blisteringOFFSIDES
422Tooth ExtractionOFFSIDES
423Tooth InfectionOFFSIDES
424Tooth LossOFFSIDES
425Tracheal StenosisOFFSIDES
426TracheobronchitisOFFSIDES
427Transmission of drug via semenOFFSIDES
428Tympanic Membrane PerforationOFFSIDES
429Ultrasound abdomen abnormalOFFSIDES
430Urticaria10982225CTD
431Uterine Neoplasms20219844CTD
432Venous occlusionOFFSIDES
433Ventricular FlutterOFFSIDES
434Ventricular internal diameter abnormalOFFSIDES
435Vertigo7875287CTD
436Visual disturbanceOFFSIDES
437Vitamin K DeficiencyOFFSIDES
438Wound InfectionOFFSIDES
439Wound dehiscenceOFFSIDES
440Wound infection bacterialOFFSIDES
441effusionOFFSIDES
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