MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Tracheobronchomegaly

(UMLS:C0040587)

Definition:: A rare and probably congenital condition characterized by great enlargement of the lumen of the trachea and the larger bronchi.
UMLS ID:: C0040587
MeSH ID:: D014137

Classification 1:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.127.930|C08.695.830|C08.907.830

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.740.830

Synonym(s)

Tracheobronchomegaly

Mounier-Kuhn Syndrome

Mounier-Kuhn syndrome

TRACHEOBRONCHOMEGALY

mounier kuhn syndrome

mounier-kuhn syndrome

tracheobronchomegaly

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Fluticasone	FAERS: 1		US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Bronchitis	41%
2	Choanal Atresia	40.4%
3	Laryngocele	40.4%
4	Tracheitis	37.6%
5	Bronchopneumonia	37.6%
6	Asthma	35.5%
7	Scimitar Syndrome	34.9%
8	Bronchitis, Chronic	33.1%
9	Kartagener Syndrome	32.8%
10	Bronchial Fistula	31.8%
11	Pleuropneumonia	30.8%
12	Bronchiolitis	30.7%
13	Bronchial Neoplasms	28.5%
14	Pleurisy	28.2%
15	Pneumonia	28.2%
16	Lobar Pneumonia	28.2%
17	Respiratory Distress Syndrome, Adult	28.2%
18	Pneumonitis	28.2%
19	Bronchospasm	28.2%
20	Bronchiectasis	28.2%
21	Tracheal Stenosis	28.2%
22	Bronchial Hyperreactivity	28.2%
23	Tracheal Neoplasms	27.7%
24	Lung diseases	26.1%
25	Pleural Diseases	26.1%
26	Respiration Disorders	26.1%
27	Thoracic Diseases	26.1%
28	Laryngostenosis	26%
29	Respiratory Distress Syndrome, Newborn	26%
30	Granuloma, Laryngeal	25.5%
31	Laryngitis	24.2%
32	Lung Diseases, Fungal	24.2%
33	Rhinitis	24.2%
34	Vocal Cord Dysfunction	24.2%
35	Lung Abscess	23.9%
36	Lung Neoplasms	23.9%
37	Pleural Neoplasms	23.9%
38	Tuberculosis, Pulmonary	23.8%
39	Asthma, Exercise-Induced	23.4%
40	Status Asthmaticus	23.4%
41	Pleural Effusion, Malignant	22.9%
42	Laryngeal Diseases	22.2%
43	Nose Diseases	22.2%
44	Primary Ciliary Dyskinesia	22%
45	Bronchiolitis Obliterans	21.8%
46	Respiratory Tract Infections	21.7%
47	Aspergillosis, Allergic Bronchopulmonary	21.5%
48	Granuloma, Respiratory Tract	21.4%
49	Respiratory Hypersensitivity	21.4%
50	Respiratory Tract Fistula	21.4%
51	Tracheobronchomegaly	21.1%
52	Meconium Aspiration Syndrome	20.9%
53	Asthma, Occupational	20.9%
54	Sinusitis	20.8%
55	Aspiration Pneumonia	20.7%
56	Hyaline Membrane Disease	19%
57	Idiopathic Pulmonary Fibrosis	18.9%
58	Laryngeal neoplasm	18.7%
59	Acute Chest Syndrome	18.3%
60	Pneumoconiosis	18.2%
61	Pneumonia, Viral	18.2%
62	Asthma, Aspirin-Induced	18.2%
63	Pneumonia, Bacterial	17.8%
64	Laryngospasm	17.6%
65	Multiple Pulmonary Nodules	17.5%
66	Bronchial Diseases	17.4%
67	Tracheal Diseases	17.4%
68	Pneumonia, Lipid	17%
69	Altitude Sickness	16.9%
70	Atelectasis	16.9%
71	Chylothorax	16.9%
72	Hydropneumothorax	16.9%
73	Hydrothorax	16.9%
74	Pulmonary Hypertension	16.9%
75	Pneumothorax	16.9%
76	Pulmonary Alveolar Proteinosis	16.9%
77	Pulmonary Edema	16.9%
78	Pulmonary Fibrosis	16.9%
79	Respiratory Insufficiency	16.9%
80	Hamman-Rich syndrome	16.9%
81	Lung Diseases, Interstitial	16.9%
82	Respiratory Depression	16.9%
83	Lung Diseases, Obstructive	16.9%
84	Respiratory Failure	16.9%
85	Paranasal Sinus Neoplasms	16.6%
86	Bronchomalacia	16.5%
87	Tracheomalacia	16.5%
88	Cystic Fibrosis	15.9%
89	Radiation Pneumonitis	15.5%
90	Radiation Fibrosis	15.5%
91	Nose Neoplasms	15%
92	Rhinoscleroma	14.9%
93	Asbestosis	14.7%
94	Berylliosis	14.7%
95	Silicosis	14.7%
96	Hoarseness	14.3%
97	Granuloma, Lethal Midline	14.1%
98	Laryngeal Edema	14.1%
99	Nose Deformities, Acquired	14.1%
100	Lung Injury	14.1%
101	Hepatopulmonary Syndrome	14.1%
102	Respiratory Aspiration	14.1%
103	Holoprosencephaly	14.1%
104	Farmer's Lung	14.1%
105	Apnea	14%
106	Cheyne-Stokes Respiration	14%
107	Common Cold	14%
108	Dyspnea	14%
109	Hemothorax	14%
110	Hyperventilation	14%
111	Influenza	14%
112	Mouth Breathing	14%
113	Persistent Fetal Circulation Syndrome	14%
114	Tachypnea	14%
115	Laryngomalacia	14%
116	Catarrh	14%
117	Hay fever	13.9%
118	Rhinitis, Allergic, Perennial	13.9%
119	Pulmonary Embolism	13.9%
120	Pulmonary Eosinophilia	13.8%
121	Severe Acute Respiratory Syndrome	13.8%
122	Eosinophilic Pneumonia	13.8%
123	Laryngopharyngeal Reflux	13.8%
124	Beckwith-Wiedemann Syndrome	13.7%
125	Wolf-Hirschhorn Syndrome	13.7%
126	Maxillary Sinus Neoplasms	13.6%
127	Abnormalities, Drug-Induced	12.7%
128	Situs Inversus	12.7%
129	Airway Obstruction	12.5%
130	Choking	12.5%
131	Epiglottitis	12.5%
132	Chronic Obstructive Airway Disease	12.5%
133	Mediastinitis	12.5%
134	Middle Lobe Syndrome	12.5%
135	Acute Lung Injury	12.5%
136	Blastomycosis	12.2%
137	Pharyngitis	12.1%
138	Smith-Magenis syndrome	12.1%
139	Aicardi's syndrome	12%
140	Nasal Polyps	12%
141	Cri-du-Chat Syndrome	11.9%
142	Down Syndrome	11.9%
143	Trisomy 21	11.9%
144	Hemoptysis	11.9%
145	Pertussis	11.8%
146	Rubinstein-Taybi Syndrome	11.3%
147	Bronchopulmonary Dysplasia	10.9%
148	Eye Abnormalities	10.8%
149	Cardiovascular Abnormalities	10.8%
150	Ectodermal Dysplasia	10.6%
151	Aplasia Cutis Congenita	10.6%
152	Skin Abnormalities	10.6%
153	Lymphatic Abnormalities	10.6%
154	Congenital Microtia	10.6%
155	Prader-Willi Syndrome	10.5%
156	Voice Disorders	10.5%
157	Voice Disturbance	10.5%
158	Mediastinal Cyst	10.5%
159	Pericardial Cyst	10.5%
160	Thymic Cyst	10.5%
161	Epistaxis	10.4%
162	Congenital diaphragmatic hernia	10.4%
163	Croup	10.3%
164	Histiocytosis, Langerhans-Cell	10.3%
165	Mediastinal Emphysema	10.3%
166	Pulmonary Emphysema	10.3%
167	Rhinitis, Vasomotor	10.3%
168	Pulmonary Aspergillosis	10.3%
169	Bronchopulmonary Aspergillosis	10.3%
170	Hypoventilation	10.3%
171	Acidosis, Respiratory	10.3%
172	Alkalosis, Respiratory	10.3%
173	Sarcoidosis, Pulmonary	10.3%
174	Sleep Apnea Syndromes	10.3%
175	Pulmonary Infarction	10.3%
176	Anencephaly	10.2%
177	Urogenital Abnormalities	9.3%
178	Vocal Cord Paralysis	9.2%
179	Maxillofacial Abnormalities	9%
180	Dural Arteriovenous Fistula	9%
181	Dextrocardia	8.9%
182	CHARGE Syndrome	8.9%
183	Tonsillitis	8.8%
184	Dyspnea, Paroxysmal	8.8%
185	Respiratory Paralysis	8.8%
186	Granulomatosis with polyangiitis	8.8%
187	Sleep Apnea, Obstructive	8.5%
188	Sleep Apnea, Central	8.5%
189	Marfan Syndrome	8.4%
190	Prune Belly Syndrome	8.3%
191	Twins, Conjoined	8.3%
192	Waardenburg Syndrome	8.3%
193	Nail-Patella Syndrome	7.8%
194	Xeroderma	7.8%
195	Mobius Syndrome	7.8%
196	Aphonia	7.7%
197	Retropharyngeal Abscess	7.7%
198	Dysphonia	7.7%
199	Anti-Glomerular Basement Membrane Disease	7.7%
200	Transfusion-Related Acute Lung Injury	7.4%
201	Invasive Pulmonary Aspergillosis	7.3%
202	Genetic Diseases, Inborn	7.2%
203	Alstrom Syndrome	7.2%
204	Acrocephalosyndactylia	7%
205	Anophthalmos	7%
206	Anus, Imperforate	7%
207	Hydranencephaly	7%
208	Microphthalmos	7%
209	Neural Tube Defects	7%
210	Tethered Cord Syndrome	7%
211	Iniencephaly	7%
212	Craniorachischisis	7%
213	Limb Deformities, Congenital	7%
214	Exencephaly	7%
215	Septo-Optic Dysplasia	7%
216	Craniofacial Abnormalities	7%
217	Cortical Dysplasia	7%
218	Malformations of Cortical Development	7%
219	Anorectal Malformations	7%
220	Microcephaly	6.9%
221	Macrocephaly	6.9%
222	Bloom Syndrome	6.9%
223	Nasopharyngitis	6.8%
224	Abnormalities, Radiation-Induced	6.8%
225	Cockayne Syndrome	6.8%
226	Polycystic Kidney Diseases	6.8%
227	Williams Syndrome	6.8%
228	Craniosynostosis	6.7%
229	Syndactyly	6.7%
230	Brachycephaly	6.7%
231	Fragile X Syndrome	6.7%
232	Turner Syndrome	6.6%
233	Classical Lissencephalies and Subcortical Band Heterotopias	6.4%
234	Peritonsillar Abscess	6.3%
235	Porencephaly	6.3%
236	Retinal Dysplasia	6.2%
237	Ichthyosis, X-Linked	6.2%
238	Aniridia	6.2%
239	Noonan Syndrome	6.1%
240	Epidermolysis Bullosa	6.1%
241	Fetal Diseases	6%
242	Smith-Lemli-Opitz Syndrome	6%
243	Blepharophimosis	6%
244	Mouth Abnormalities	6%
245	Cleft Palate	6%
246	Esophageal Atresia	5.9%
247	Intestinal Atresia	5.9%
248	Horseshoe Kidney	5.9%
249	Pectus excavatum	5.9%
250	Klippel-Feil Syndrome	5.9%
251	Gastroschisis	5.9%
252	Synostosis	5.9%
253	Acrodermatitis	5.9%
254	Lymphangiectasis, Intestinal	5.9%
255	Gianotti-Crosti Syndrome	5.9%
256	Eosinophilic Granuloma	5.7%
257	Jaw Abnormalities	5.6%
258	Poland Syndrome	5.5%
259	Klinefelter Syndrome	5.3%
260	Arthrogryposis	5.3%
261	Choledochal Cyst	5.2%
262	Hermaphroditism	5.2%
263	Disorders of Sex Development	5.2%
264	Cryptorchidism	5.2%
265	Hypospadias	5.2%
266	Central Nervous System Cysts	5.2%
267	Amelia	5.1%
268	Arachnodactyly	5.1%
269	Ectopia Cordis	5.1%
270	Ectromelia	5.1%
271	Hemimelia	5.1%
272	Meningomyelocele	5.1%
273	Phocomelia	5.1%
274	Sirenomelia	5.1%
275	Spina Bifida	5.1%
276	Polydactyly	5.1%
277	Brachydactyly	5.1%
278	Plagiocephaly	5.1%
279	Lower Extremity Deformities, Congenital	5.1%
280	Upper Extremity Deformities, Congenital	5.1%
281	Single umbilical artery	5.1%
282	Dandy-Walker Syndrome	5.1%
283	POEMS Syndrome	5.1%
284	Polycystic Kidney, Autosomal Dominant	5%
285	Sjogren-Larsson Syndrome	5%
286	Pseudoxanthoma Elasticum	5%
287	Micrognathism	4.8%
288	Pierre Robin Syndrome	4.8%
289	Pectus carinatum	4.6%
290	Bladder Exstrophy	4.6%
291	Epispadias	4.6%
292	Xeroderma Pigmentosum	4.5%
293	Kallmann Syndrome	4.5%
294	Multicystic Dysplastic Kidney	4.5%
295	Hyperkeratosis, Epidermolytic	4.5%
296	Charcot-Marie-Tooth Disease	4.5%
297	Antley-Bixler Syndrome Phenotype	4.5%
298	Aortic coarctation	4.4%
299	Cor Triatriatum	4.4%
300	Coronary Vessel Anomalies	4.4%
301	Dental Enamel Hypoplasia	4.4%
302	Patent ductus arteriosus	4.4%
303	Ebstein Anomaly	4.4%
304	Heart Septal Defects	4.4%
305	Hypodontia	4.4%
306	Macrostomia	4.4%
307	Meningocele	4.4%
308	Microstomia	4.4%
309	Tetralogy of Fallot	4.4%
310	Transposition of Great Vessels	4.4%
311	Hypoplastic Left Heart Syndrome	4.4%
312	May-Thurner Syndrome	4.4%
313	Encephalocele	4.4%
314	Craniofacial Dysostosis	4.4%
315	Wolff-Parkinson-White Syndrome	4.3%
316	Retrognathia	4.3%
317	Zellweger Syndrome	4.3%
318	Dermal Sinus	4.2%
319	Spina Bifida Cystica	4.2%
320	Spina Bifida Occulta	4.2%
321	Lissencephaly	4.2%
322	Polymicrogyria	4.2%
323	Pachygyria	4.2%
324	Schizencephaly	4.2%
325	Periventricular Nodular Heterotopia	4.2%
326	Abdominal Cramps	4.2%
327	Amniotic Band Syndrome	4.2%
328	Asphyxia Neonatorum	4.2%
329	Infant, Premature, Diseases	4.2%
330	Infantile Colic	4.2%
331	Hyperandrogenism	4.1%
332	Basal Cell Nevus Syndrome	4.1%
333	Tuberous Sclerosis	4.1%
334	Prognathism	4%
335	Refsum Disease	4%
336	Long QT Syndrome	3.8%
337	Platybasia	3.8%
338	Tricuspid Atresia	3.8%
339	Arrhythmogenic Right Ventricular Dysplasia	3.8%
340	Gonadal Dysgenesis	3.8%
341	Adrenogenital Syndrome	3.8%
342	Ovotesticular Disorders of Sex Development	3.8%
343	Aortopulmonary Septal Defect	3.6%
344	Double Outlet Right Ventricle	3.6%
345	Endocardial Cushion Defects	3.6%
346	Neoplastic Syndromes, Hereditary	3.6%
347	Myocardial bridging	3.6%
348	Aorticopulmonary Septal Defect	3.6%
349	Anemia, Neonatal	3.5%
350	Multiple Epiphyseal Dysplasia	3.5%
351	Osteochondrodysplasias	3.5%
352	Pelger-Huet Anomaly	3.5%
353	Werner Syndrome	3.5%
354	Myasthenic Syndromes, Congenital	3.5%
355	Umbilical hernia	3.5%
356	Anemia, Sickle Cell	3.4%
357	Thalassemia	3.4%
358	Albinism	3.4%
359	Muscular Dystrophy, Duchenne	3.4%
360	Truncus Arteriosus, Persistent	3.2%
361	Goldenhar Syndrome	3.2%
362	Mandibulofacial Dysostosis	3.2%
363	Romano-Ward Syndrome	3.1%
364	Dwarfism	3.1%
365	Neonatal Abstinence Syndrome	3%
366	Mucopolysaccharidosis II	3%
367	Fetal Growth Retardation	3%
368	Muscular Dystrophy	3%
369	Osteogenesis Imperfecta	3%
370	Fetal Hypoxia	3%
371	Congenital nystagmus	3%
372	Fetal Alcohol Spectrum Disorders	3%
373	Toxoplasmosis, Congenital	2.9%
374	Syphilis, Congenital	2.9%
375	Rett Syndrome	2.9%
376	Talipes	2.8%
377	Menkes Kinky Hair Syndrome	2.8%
378	Familial Mediterranean Fever	2.8%
379	Wiskott-Aldrich Syndrome	2.7%
380	Congenital clubfoot	2.7%
381	Vertical Talus	2.7%
382	Autoimmune Lymphoproliferative Syndrome	2.6%
383	Congenital Hyperinsulinism	2.6%
384	Chorioamnionitis	2.6%
385	Angioedemas, Hereditary	2.6%
386	Sickle Cell Trait	2.5%
387	Arteriovenous fistula	2.5%
388	Myotonic Dystrophy	2.4%
389	Neuronal Ceroid-Lipofuscinoses	2.4%
390	Adrenoleukodystrophy	2.4%
391	Paralysis, Obstetric	2.3%
392	Retinopathy of Prematurity	2.3%
393	Amino Acid Metabolism, Inborn Errors	2.3%
394	Carbohydrate Metabolism, Inborn Errors	2.3%
395	Metal Metabolism, Inborn Errors	2.3%
396	Progeria	2.3%
397	Lysosomal Storage Diseases	2.3%
398	Cytochrome-c Oxidase Deficiency	2.3%
399	Peroxisomal Disorders	2.3%
400	Hepatolenticular Degeneration	2.2%
401	Fabry Disease	2.2%
402	Denys-Drash Syndrome	2.1%
403	Amyloid Neuropathies, Familial	2.1%
404	Glycogen storage disease type II	2%
405	Ophthalmia Neonatorum	2%
406	Galactosemias	2%
407	Urea Cycle Disorders, Inborn	2%
408	Tyrosinemias	2%
409	Hydrops Fetalis	2%
410	Cutis Laxa	2%
411	Retinitis Pigmentosa	2%
412	Pigmentary retinopathy	2%
413	Porokeratosis	2%
414	Keratoderma, Palmoplantar	2%
415	Chronic granulomatous disease	2%
416	Welander Distal Myopathy	1.9%
417	Ataxia Telangiectasia	1.9%
418	Mucopolysaccharidosis III	1.8%
419	Optic Atrophy, Hereditary, Leber	1.8%
420	Hyperphosphaturia	1.8%
421	Canavan Disease	1.8%
422	Alexander Disease	1.8%
423	Duane Retraction Syndrome	1.7%
424	Porphyrias, Hepatic	1.7%
425	Alkaptonuria	1.7%
426	Glycogen Storage Disease	1.7%
427	Hypophosphatasia	1.7%
428	Propionic acidemia	1.7%
429	Dihydropyrimidine Dehydrogenase Deficiency	1.7%
430	Cystinosis	1.7%
431	Peutz-Jeghers Syndrome	1.7%
432	Myotonia Congenita	1.7%
433	Thrombasthenia	1.7%
434	Antithrombin III Deficiency	1.7%
435	Protein C Deficiency	1.7%
436	Brain Diseases, Metabolic, Inborn	1.7%
437	Afibrinogenemia	1.7%
438	Dystonia Musculorum Deformans	1.7%
439	Factor VII Deficiency	1.7%
440	Factor X Deficiency	1.7%
441	Factor XII Deficiency	1.7%
442	Hemophilia A	1.7%
443	Leukomalacia, Periventricular	1.7%
444	Activated Protein C Resistance	1.7%
445	Factor II deficiency	1.7%
446	Factor VIII Deficiency	1.7%
447	Factor V deficiency	1.7%
448	Factor XI Deficiency	1.7%
449	Hypoprothrombinemias	1.7%
450	Gaucher Disease	1.7%
451	Fanconi Anemia	1.7%
452	Nesidioblastosis	1.7%
453	Lafora Disease	1.7%
454	Unverricht-Lundborg Syndrome	1.7%
455	Anemia, Diamond-Blackfan	1.7%
456	Homocystinuria	1.7%
457	Leigh Disease	1.7%
458	Multiple Endocrine Neoplasia	1.6%
459	Tay-Sachs Disease	1.5%
460	Congenital Hypothyroidism	1.5%
461	Dermatitis, Atopic	1.5%
462	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.5%
463	Niemann-Pick Disease, Type C	1.5%
464	Hypolipoproteinemias	1.4%
465	Papillon-Lefevre Disease	1.4%
466	Hyperlipidemia, Familial Combined	1.4%
467	Hyperlipoproteinemia Type III	1.4%
468	Glycogen Storage Disease Type I	1.4%
469	Glycogen Storage Disease Type V	1.4%
470	Kernicterus	1.4%
471	Behcet Syndrome	1.4%
472	Familial Periodic Paralysis	1.3%
473	Lactose Intolerance	1.3%
474	Variegate Porphyria	1.3%
475	Acute intermittent porphyria	1.3%
476	Porphyria Cutanea Tarda	1.3%
477	Hyperhomocysteinemia	1.3%
478	Renal Aminoacidurias	1.3%
479	Fanconi Syndrome	1.3%
480	Pseudohypoaldosteronism	1.3%
481	Liddle Syndrome	1.3%
482	Hyperlipoproteinemia Type IV	1.3%
483	Hyperlipoproteinemia Type V	1.3%
484	Huntington Disease	1.2%
485	Hypoalphalipoproteinemias	1.2%
486	Gout	1.1%
487	Multiple Endocrine Neoplasia Type 1	1.1%
488	Pseudohypoparathyroidism	1.1%
489	Friedreich Ataxia	1.1%
490	Nephroblastoma	1.1%
491	Renal tubular acidosis	1.1%
492	Hypokalemic periodic paralysis	1.1%
493	Cystinuria	1%
494	Adenomatous Polyposis Coli	1%
495	Familial Hypophosphatemic Rickets	1%
496	Arthritis, Gouty	0.9%
497	Glycosuria, Renal	0.9%
498	MELAS Syndrome	0.8%

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