MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Mallory-Weiss Syndrome

(UMLS:C0024633)

Definition:: A condition characterized by mucosal tears at the ESOPHAGOGASTRIC JUNCTION, sometimes with HEMATEMESIS. Typically it is caused by forceful bouts of retching or VOMITING.
UMLS ID:: C0024633
MeSH ID:: D008309

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405.117.468.524

Synonym(s)

Mallory-Weiss Syndrome

ESOPHAGUS TEAR

GASTROESOPHAGEAL MUCOSAL LACERATION-HEMORRHAGE SYNDROME

GASTROESOPHAGEAL MUCOSAL TEAR

Gastro-esophageal laceration syndrome

Gastro-esophageal laceration-hemorrhage syndrome

Gastro-oesophageal laceration-haemorrhage syndrome

Gastroesophageal laceration-haemorrhage syndrome

Gastroesophageal laceration-hemorrhage syndrome

10.

MALLORY WEISS SYNDROME

11.

MALLORY WEISS TEAR

12.

MALLORY-WEISS SYNDROME

13.

MALLORY-WEISS TEAR

14.

Mallory Weiss Syndrome

15.

Mallory Weiss syndrome

16.

Mallory-Weiss

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Rivaroxaban	FAERS: 23	US FAERS
2	Isotretinoin	FAERS: 14	US FAERS
3	Ibuprofen	FAERS: 11	US FAERS
4	Warfarin	FAERS: 11	US FAERS
5	Sunitinib	FAERS: 10	US FAERS
6	Dabigatran	FAERS: 8	US FAERS
7	Warfarin	FAERS: 7	US FAERS
8	Alendronate	FAERS: 6	US FAERS
9	Aspirin	FAERS: 6	US FAERS
10	Acetaminophen	FAERS: 5	US FAERS
11	Varenicline	FAERS: 5	US FAERS
12	Benicar hct	FAERS: 4	US FAERS
13	Olmesartan Medoxomil	FAERS: 4	US FAERS
14	Omeprazole	FAERS: 4	US FAERS
15	Sorafenib	FAERS: 4	US FAERS
16	apixaban	FAERS: 4	OFFSIDES US FAERS
17	rofecoxib	FAERS: 4	OFFSIDES US FAERS
18	Aripiprazole	FAERS: 3	US FAERS
19	Clopidogrel	FAERS: 3	US FAERS
20	Deferasirox	FAERS: 3	US FAERS
21	Ruxolitinib phosphate	FAERS: 3	US FAERS
22	Atomoxetine Hydrochloride	FAERS: 2	US FAERS
23	Bortezomib	FAERS: 2	OFFSIDES US FAERS
24	Dabigatran	FAERS: 2	US FAERS
25	Diclofenac	FAERS: 2	US FAERS
26	Donepezil	FAERS: 2	US FAERS
27	Insulin Glargine	FAERS: 2	US FAERS
28	Lamotrigine	FAERS: 2	US FAERS
29	Levofloxacin	FAERS: 2	US FAERS
30	Naproxen	FAERS: 2	US FAERS
31	PCI 32765	FAERS: 2	US FAERS
32	ixazomib	FAERS: 2	US FAERS
33	reviparin	FAERS: 2	US FAERS
34	Amoxicillin	FAERS: 1	OFFSIDES US FAERS
35	Busulfan	FAERS: 1	US FAERS
36	Cinacalcet	FAERS: 1	US FAERS
37	Cinacalcet	FAERS: 1	OFFSIDES US FAERS
38	Dimethyl Fumarate	FAERS: 1	US FAERS
39	Docetaxel	FAERS: 1	US FAERS
40	Doxycycline	FAERS: 1	US FAERS
41	Duloxetine Hydrochloride	FAERS: 1	US FAERS
42	Epirubicin	FAERS: 1	US FAERS
43	Epoprostenol	FAERS: 1	US FAERS
44	Erlotinib Hydrochloride	FAERS: 1	US FAERS
45	Ezetimibe, Simvastatin Drug Combination	FAERS: 1	US FAERS
46	Felbamate	FAERS: 1	US FAERS
47	Fluoxetine	FAERS: 1	US FAERS
48	Gentamicins	FAERS: 1	US FAERS
49	Guaifenesin	FAERS: 1	US FAERS
50	Hydromorphone	FAERS: 1	US FAERS
51	INCB018424	FAERS: 1	US FAERS
52	Itraconazole	FAERS: 1	US FAERS
53	Ketorolac Tromethamine	FAERS: 1	US FAERS
54	Memantine	FAERS: 1	US FAERS
55	Methylprednisolone	FAERS: 1	US FAERS
56	Mitomycin	FAERS: 1	US FAERS
57	Nebivolol	FAERS: 1	US FAERS
58	Pioglitazone	FAERS: 1	US FAERS
59	Prasugrel Hydrochloride	FAERS: 1	US FAERS
60	Prasugrel Hydrochloride	FAERS: 1	US FAERS
61	Raloxifene Hydrochloride	FAERS: 1	US FAERS
62	Rivastigmine	FAERS: 1 Canada Vigilance: 1	Canada Vigilance OFFSIDES US FAERS
63	Sertraline	FAERS: 1	US FAERS
64	Sildenafil Citrate	FAERS: 1	US FAERS
65	Sitagliptin Phosphate	FAERS: 1	US FAERS
66	Sunitinib	FAERS: 1	US FAERS
67	Temozolomide	FAERS: 1	OFFSIDES US FAERS
68	Thalidomide	FAERS: 1	US FAERS
69	Tramadol hydrochloride and acetaminophen	FAERS: 1	US FAERS
70	Zoledronic Acid	FAERS: 1	OFFSIDES US FAERS
71	apremilast	FAERS: 1	US FAERS
72	cefuroxime axetil	FAERS: 1	OFFSIDES US FAERS
73	edoxaban	FAERS: 1	US FAERS
74	entecavir	FAERS: 1	US FAERS
75	gemcitabine	FAERS: 1	US FAERS
76	pazopanib	FAERS: 1	US FAERS
77	regorafenib	FAERS: 1	US FAERS
78	romidepsin	FAERS: 1	US FAERS
79	tofacitinib	FAERS: 1	US FAERS
80	Alosenn		OFFSIDES
81	Aluminum Hydroxide		OFFSIDES
82	Amifostine		OFFSIDES
83	Amisulpride		OFFSIDES
84	Amlodipine		OFFSIDES
85	Bisacodyl		OFFSIDES
86	Carbamazepine		OFFSIDES
87	Carbimazole		OFFSIDES
88	Cefazolin		OFFSIDES
89	Cephalexin		OFFSIDES
90	Chlorpropamide		OFFSIDES
91	Clopidogrel		OFFSIDES
92	Clozapine	Canada Vigilance: 1	Canada Vigilance
93	Dextromethorphan		OFFSIDES
94	Didanosine		OFFSIDES
95	Dioctyl Sulfosuccinic Acid		OFFSIDES
96	Disopyramide		OFFSIDES
97	Dronabinol		OFFSIDES
98	Ethylene Glycol		OFFSIDES
99	Flunitrazepam		OFFSIDES
100	Glipizide		OFFSIDES
101	Glyburide		OFFSIDES
102	Hydroxyurea		OFFSIDES
103	Ibandronic Acid		OFFSIDES
104	Irinotecan		OFFSIDES
105	Kanamycin		OFFSIDES
106	Lanthanum carbonate hydrate		OFFSIDES
107	Mannitol		OFFSIDES
108	Meperidine		OFFSIDES
109	Metformin		OFFSIDES
110	Methotrimeprazine		OFFSIDES
111	Metoclopramide		OFFSIDES
112	Minocycline		OFFSIDES
113	Nabumetone		OFFSIDES
114	NuvaRing		OFFSIDES
115	Pemetrexed		OFFSIDES
116	Phenylephrine		OFFSIDES
117	Pirenzepine		OFFSIDES
118	Prednisone acetate		OFFSIDES
119	Rosiglitazone		OFFSIDES
120	Sevelamer		OFFSIDES
121	Sodium picosulfate		OFFSIDES
122	Taurine		OFFSIDES
123	Temazepam		OFFSIDES
124	Tretinoin		OFFSIDES
125	Valacyclovir		OFFSIDES
126	alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination		OFFSIDES
127	almotriptan		OFFSIDES
128	anagrelide		OFFSIDES
129	bicalutamide		OFFSIDES
130	efavirenz		OFFSIDES
131	ferrous fumarate		OFFSIDES
132	gadoversetamide		OFFSIDES
133	imidapril		OFFSIDES
134	magnesium citrate		OFFSIDES
135	norgestimate, ethinyl estradiol drug combination		OFFSIDES
136	sennoside A&B		OFFSIDES
137	tegaserod		OFFSIDES
138	tramazoline		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Esophageal Stenosis	34.4%
2	Esophagitis	33%
3	Esophageal and Gastric Varices	26.4%
4	Gastroenteritis	25.4%
5	Intestinal Diseases	25.4%
6	Stomach Diseases	25.4%
7	Barrett Esophagus	23.6%
8	Deglutition Disorders	23.6%
9	Esophageal motility disorders	22.6%
10	Esophageal Atresia	21.8%
11	Dysentery	19.8%
12	Enteritis	19.8%
13	Enterocolitis	19.8%
14	Gastritis	19.8%
15	Inflammatory Bowel Diseases	19.8%
16	Esophageal Neoplasms	18.1%
17	Gastrointestinal Neoplasms	17.1%
18	Gastrointestinal Hemorrhage	16.9%
19	Esophageal Achalasia	16.8%
20	Zollinger-Ellison syndrome	16.6%
21	Tuberculosis, Gastrointestinal	16.5%
22	Biliary Tract Diseases	16.4%
23	Liver diseases	16.4%
24	Pancreatic Diseases	16.4%
25	Colitis	16.3%
26	Duodenogastric Reflux	16.3%
27	Peptic Ulcer	16.3%
28	Proctitis	16.3%
29	Cecal Diseases	14.8%
30	Colonic Diseases	14.8%
31	Ileal Diseases	14.8%
32	Intestinal Obstruction	14.8%
33	Intestinal Perforation	14.8%
34	Jejunal Diseases	14.8%
35	Pneumatosis Cystoides Intestinalis	14.8%
36	Rectal Diseases	14.8%
37	Gastric Dilatation	14.8%
38	Gastric outlet obstruction	14.8%
39	Cronkhite-Canada Syndrome	14.8%
40	Intestinal Polyposis	14.8%
41	Duodenitis	14.5%
42	Ileitis	14.5%
43	Erosive Duodenitis	14.5%
44	Intestinal Neoplasms	13.8%
45	Stomach Neoplasms	13.8%
46	Proctocolitis	13.6%
47	Crohn Disease	12.9%
48	Duodenal Obstruction	12.9%
49	Enterocolitis, Neutropenic	12.9%
50	Necrotizing Enterocolitis	12.9%
51	Appendicitis	12.3%
52	Mesenteric vascular insufficiency	12%
53	Colorectal Neoplasms	12%
54	Intestinal Atresia	11.8%
55	Mesenteric Vascular Occlusion	11.8%
56	Intestinal Fistula	11.7%
57	Enterocutaneous Fistula	11.7%
58	Duodenal Ulcer	11.2%
59	Peptic Ulcer Perforation	11.2%
60	Gastric ulcer	11.2%
61	Digestive System Neoplasms	10.8%
62	Pouchitis	10.8%
63	Cecal Neoplasms	10.7%
64	Duodenal Neoplasms	10.7%
65	Intestinal Diseases, Parasitic	10.6%
66	Achlorhydria	9.9%
67	Gastric Antral Vascular Ectasia	9.9%
68	Gastrointestinal Stromal Tumors	9.8%
69	Peptic Ulcer Hemorrhage	9.8%
70	Gastroparesis	9.8%
71	Rectal Fistula	9.7%
72	Anal Fistula	9.7%
73	Colonic Diseases, Functional	9.7%
74	Enterocolitis, Pseudomembranous	9.7%
75	Fecal Incontinence	9.7%
76	Fecal Impaction	9.7%
77	Intussusception	9.7%
78	Megacolon	9.7%
79	Pyloric Stenosis	9.7%
80	pseudomembranous colitis	9.7%
81	Ileus	9.7%
82	Dysentery, Bacillary	9.7%
83	Meconium ileus	9.7%
84	Laryngopharyngeal Reflux	9.6%
85	Colonic Pseudo-Obstruction	8.8%
86	Colitis, Ischemic	8.6%
87	Liver neoplasms	8.5%
88	Bile Duct Diseases	8.5%
89	Cholelithiasis	8.5%
90	Chylous Ascites	8.5%
91	Fatty Liver	8.5%
92	Hepatitis	8.5%
93	Portal Hypertension	8.5%
94	Liver Cirrhosis	8.5%
95	Pancreatic Fistula	8.5%
96	Pancreatic Insufficiency	8.5%
97	Pancreatitis	8.5%
98	Pneumoperitoneum	8.5%
99	Focal Nodular Hyperplasia	8.5%
100	Hepatic Insufficiency	8.5%
101	Steatohepatitis	8.5%
102	Appendiceal Neoplasms	7.9%
103	Colonic Neoplasms	7.9%
104	Rectal Neoplasms	7.9%
105	Anus Neoplasms	7.7%
106	Sigmoid Neoplasms	7.7%
107	Melena	7.5%
108	Hematemesis	7.3%
109	Anal Fissure	7.2%
110	Intestinal Pseudo-Obstruction	7.2%
111	Irritable Bowel Syndrome	7.2%
112	Superior Mesenteric Artery Syndrome	7.2%
113	Neurogenic Bowel	7.2%
114	Anal Ulcer	7.2%
115	Peritoneal Neoplasms	6.8%
116	Adenomatous Polyposis Coli	6.8%
117	Hemorrhoids	6.7%
118	Cholecystolithiasis	6.6%
119	Afferent Loop Syndrome	6.5%
120	Celiac Disease	6.5%
121	Short Bowel Syndrome	6.5%
122	Sprue, Tropical	6.5%
123	Steatorrhea	6.5%
124	Rectocele	6.5%
125	Sprue	6.5%
126	Diverticulitis	6.5%
127	Dumping Syndrome	6.5%
128	Rectal Prolapse	6.5%
129	Biliary cirrhosis	6.1%
130	Liver Diseases, Parasitic	6%
131	Bile Duct Neoplasms	5.9%
132	gallbladder neoplasm	5.9%
133	Hepatic Veno-Occlusive Disease	5.7%
134	Pancreatic Cyst	5.7%
135	Peliosis Hepatis	5.7%
136	Hepatopulmonary Syndrome	5.7%
137	Pancreatic Neoplasm	5.7%
138	Anus, Imperforate	5.6%
139	Hemoperitoneum	5.6%
140	Hepatomegaly	5.6%
141	Mesenteric Panniculitis	5.6%
142	Panniculitis, Peritoneal	5.6%
143	Peritonitis	5.6%
144	Peritoneal Fibrosis	5.6%
145	Encapsulating Peritoneal Sclerosis	5.6%
146	Anorectal Malformations	5.6%
147	Biliary Fistula	5.6%
148	Gastric Fistula	5.6%
149	Hepatic Vein Thrombosis	5.5%
150	Liver Abscess	5.5%
151	Budd-Chiari Syndrome	5.5%
152	Choledochal Cyst	5.4%
153	Choledocholithiasis	5.4%
154	Giardiasis	5.1%
155	Diverticulum	5%
156	Diverticulosis	5%
157	Cholangitis	4.9%
158	Cholecystitis	4.9%
159	Cholestasis	4.9%
160	Common Bile Duct Diseases	4.9%
161	Hepatitis, Chronic	4.9%
162	Liver Failure	4.9%
163	Pancreatitis, Chronic	4.9%
164	Non-alcoholic Fatty Liver Disease	4.9%
165	Chronic active hepatitis	4.9%
166	Fatty Liver, Alcoholic	4.9%
167	Hepatitis, Alcoholic	4.9%
168	Liver Cirrhosis, Alcoholic	4.9%
169	Pruritus Ani	4.9%
170	CREST Syndrome	4.8%
171	Chemical and Drug Induced Liver Injury	4.3%
172	Hepatorenal Syndrome	4.2%
173	Peutz-Jeghers Syndrome	4%
174	Hepatocellular Adenoma	3.9%
175	Lactose Intolerance	3.9%
176	Hepatitis, Animal	3.5%
177	Hepatitis, Viral, Human	3.5%
178	Cystic Fibrosis	3.5%
179	Porphyrias, Hepatic	3.4%
180	Congenital Hyperinsulinism	3.4%
181	Liver Abscess, Amebic	3.3%
182	Liver Neoplasms, Experimental	3.3%
183	Liver Cirrhosis, Experimental	3.3%
184	Pancreatic Pseudocyst	3.3%
185	Pancreatitis, Alcoholic	3.3%
186	Cholestasis, Extrahepatic	3.2%
187	Biliary Dyskinesia	3.2%
188	Cholangitis, Sclerosing	3.2%
189	Liver Failure, Acute	3.2%
190	Acalculous Cholecystitis	3.2%
191	End Stage Liver Disease	3.2%
192	Cryptosporidiosis	2.9%
193	Fascioliasis	2.5%
194	Echinococcosis, Hepatic	2.5%
195	Chemical and Drug Induced Liver Injury, Chronic	2.5%
196	Reye Syndrome	2.5%
197	Carcinoma, Pancreatic Ductal	2.4%
198	Massive Hepatic Necrosis	2.4%
199	Emphysematous Cholecystitis	2.4%
200	Sphincter of Oddi Dysfunction	2.4%
201	Hepatitis B, Chronic	2.3%
202	Hepatitis C, Chronic	2.3%
203	Autoimmune hepatitis	2.2%
204	Nesidioblastosis	1.9%
205	Variegate Porphyria	1.9%
206	Acute intermittent porphyria	1.9%
207	Porphyria Cutanea Tarda	1.9%
208	insulinoma	1.8%
209	Gastrinoma	1.8%
210	Glucagonoma	1.8%
211	Hepatitis, Viral, Animal	1.8%
212	Hepatitis E	1.7%
213	Hepatitis B	1.7%
214	Hepatitis C	1.7%
215	Hepatitis A	1.7%
216	Hepatic Encephalopathy	1.6%
217	Vipoma	1.6%
218	Zellweger Syndrome	1.5%
219	Hepatolenticular Degeneration	1.4%
220	Rift Valley Fever	0.7%

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