MetaADEDB 2.0 @ LMMD
Hydroxyurea
(VSNHCAURESNICA-UHFFFAOYSA-N)
Structure
SMILES
NC(=O)NO
Type(s)
Approved
ATC code(s)
L01XX05
Molecular Formula:
CH4N2O2
Molecular Weight:
76.055
Log P:
0.1351
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
3
TPSA:
75.35
CAS Number(s):
127-07-1; 8029-68-3
Synonym(s)
1.
Hydroxyurea
2.
Hydroxycarbamid
3.
Hydrea
4.
Oncocarbide
External Link(s)
MeSHD006918
PubChem Compound3657
BindingDB50017811
ChEBI44423
CHEMBLCHEMBL467
DrugBankDB01005
DrugCentral1399
IUPHAR/BPS Guide to PHARMACOLOGY6822
KEGGcpd:C07044
dr:D00341
Therapeutic Target DatabaseD07CWD
ZINC8034120
100019199
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Product use in unapproved indicationFAERS: 49
Canada Vigilance: 3
Canada Vigilance
US FAERS
2Skin UlcerFAERS: 49
Canada Vigilance: 2
10682958CTD
SIDER
Canada Vigilance
US FAERS
3ThrombocytopeniaFAERS: 33
Canada Vigilance: 1
4692124
12620292
CTD
SIDER
Canada Vigilance
US FAERS
4NauseaFAERS: 27
Canada Vigilance: 1

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CTD
SIDER
Canada Vigilance
US FAERS
5Drug ineffectiveFAERS: 26
Canada Vigilance: 4
Canada Vigilance
OFFSIDES
US FAERS
6FatigueFAERS: 23
Canada Vigilance: 4
11061656CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
7Actinic keratosisFAERS: 22
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
8Cerebrovascular accidentFAERS: 20US FAERS
9HeadacheFAERS: 20
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
10Malignant neoplasm progressionFAERS: 19OFFSIDES
US FAERS
11AstheniaFAERS: 18OFFSIDES
SIDER
US FAERS
12PneumoniaFAERS: 18US FAERS
13ErythemaFAERS: 16

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CTD
SIDER
US FAERS
14PainFAERS: 16OFFSIDES
SIDER
US FAERS
15PregnancyFAERS: 15US FAERS
16Product use issueFAERS: 15US FAERS
17Squamous cell carcinomaFAERS: 15US FAERS
18ChillsFAERS: 14SIDER
US FAERS
19DizzinessFAERS: 14SIDER
US FAERS
20Maternal exposure during pregnancyFAERS: 14US FAERS
21Adverse eventFAERS: 13US FAERS
22VomitingFAERS: 13
Canada Vigilance: 1

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CTD
SIDER
Canada Vigilance
US FAERS
23ArthralgiaFAERS: 12US FAERS
24MalaiseFAERS: 12SIDER
US FAERS
25PancytopeniaFAERS: 12SIDER
US FAERS
26AlopeciaFAERS: 11SIDER
US FAERS
27DermatomyositisFAERS: 1118625537CTD
OFFSIDES
SIDER
US FAERS
28Drug administered to patient of inappropriate ageFAERS: 11US FAERS
29Nail pigmentationFAERS: 11OFFSIDES
SIDER
US FAERS
30Wrong technique in product usage processFAERS: 11US FAERS
31Basal cell carcinomaFAERS: 10OFFSIDES
US FAERS
32NeutropeniaFAERS: 10SIDER
US FAERS
33White blood cell count decreasedFAERS: 10
Canada Vigilance: 1
Canada Vigilance
US FAERS
34Abdominal PainFAERS: 9US FAERS
35Accidental exposureFAERS: 9US FAERS
36Cytogenetic analysis abnormalFAERS: 9US FAERS
37InfectionFAERS: 9SIDER
US FAERS
38MYELODYSPLASTIC SYNDROMEFAERS: 9US FAERS
39MyalgiaFAERS: 9US FAERS
40Platelet count abnormalFAERS: 9OFFSIDES
US FAERS
41PruritusFAERS: 97499134CTD
US FAERS
42Respiratory FailureFAERS: 9US FAERS
43Back PainFAERS: 8
Canada Vigilance: 2
Canada Vigilance
US FAERS
44Cerebral InfarctionFAERS: 8US FAERS
45DementiaFAERS: 8US FAERS
46Dry skinFAERS: 8
Canada Vigilance: 1
Canada Vigilance
US FAERS
47General physical health deteriorationFAERS: 8OFFSIDES
US FAERS
48LymphomaFAERS: 8US FAERS
49Product quality issueFAERS: 8US FAERS
50EpistaxisFAERS: 7OFFSIDES
US FAERS
51FractureFAERS: 7US FAERS
52LeukopeniaFAERS: 7

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CTD
SIDER
US FAERS
53Squamous cell carcinoma of skinFAERS: 7OFFSIDES
US FAERS
54Treatment related secondary malignancyFAERS: 7OFFSIDES
US FAERS
55Acute myocardial infarctionFAERS: 6US FAERS
56AngioedemaFAERS: 6US FAERS
57AzoospermiaFAERS: 6OFFSIDES
SIDER
US FAERS
58HypersensitivityFAERS: 6SIDER
US FAERS
59PhlebitisFAERS: 6US FAERS
60PneumonitisFAERS: 6US FAERS
61Product substitution issueFAERS: 6US FAERS
62Pulmonary EmbolismFAERS: 6US FAERS
63SepsisFAERS: 6US FAERS
64SplenomegalyFAERS: 6
Canada Vigilance: 1
Canada Vigilance
US FAERS
65White blood cell count abnormalFAERS: 6OFFSIDES
US FAERS
66Blood count abnormalFAERS: 5OFFSIDES
US FAERS
67Depressed Level of ConsciousnessFAERS: 5US FAERS
68DisorientationFAERS: 5SIDER
US FAERS
69Drug administration errorFAERS: 5US FAERS
70OverdoseFAERS: 5US FAERS
71Skin necrosisFAERS: 5OFFSIDES
SIDER
US FAERS
72Therapeutic response unexpected with drug substitutionFAERS: 5US FAERS
73ThrombosisFAERS: 59025160
12707224
CTD
US FAERS
74TremorFAERS: 5US FAERS
75UlcerFAERS: 5
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
76VasculitisFAERS: 59095664CTD
US FAERS
77Accidental overdoseFAERS: 4US FAERS
78Blood creatinine increasedFAERS: 4OFFSIDES
SIDER
US FAERS
79CellulitisFAERS: 4US FAERS
80Enterococcal infectionFAERS: 4US FAERS
81Erythema MultiformeFAERS: 4US FAERS
82FibrosisFAERS: 4SIDER
US FAERS
83Gastric ulcerFAERS: 4US FAERS
84HepatitisFAERS: 47374520
9091401
10433603
CTD
US FAERS
85LeukocytosisFAERS: 417136541CTD
US FAERS
86Lip and/or oral cavity cancerFAERS: 4US FAERS
87LymphopeniaFAERS: 4US FAERS
88Myocardial InfarctionFAERS: 415692605CTD
US FAERS
89No adverse eventFAERS: 4US FAERS
90Ovarian failureFAERS: 4OFFSIDES
US FAERS
91PalpitationsFAERS: 4US FAERS
92PancreatitisFAERS: 4OFFSIDES
SIDER
US FAERS
93Pulmonary FibrosisFAERS: 4SIDER
US FAERS
94SclerodermaFAERS: 4OFFSIDES
US FAERS
95StomatitisFAERS: 4
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
96ThrombocytosisFAERS: 411722451
12707224
15813844
CTD
US FAERS
97UrticariaFAERS: 4US FAERS
98Visual disturbanceFAERS: 4OFFSIDES
US FAERS
99Weight decreasedFAERS: 4
Canada Vigilance: 3
Canada Vigilance
US FAERS
100Abdominal discomfortFAERS: 3
Canada Vigilance: 2
Canada Vigilance
US FAERS
101AnorexiaFAERS: 3OFFSIDES
SIDER
US FAERS
102ArthropathyFAERS: 3US FAERS
103Atrial FibrillationFAERS: 3US FAERS
104Bacterial sepsisFAERS: 3US FAERS
105Blood alkaline phosphatase increasedFAERS: 3OFFSIDES
US FAERS
106Blood lactate dehydrogenase increasedFAERS: 3OFFSIDES
US FAERS
107Bowen's DiseaseFAERS: 3US FAERS
108Bronchopulmonary AspergillosisFAERS: 3US FAERS
109Burning sensationFAERS: 3US FAERS
110Circumstance or information capable of leading to medication errorFAERS: 3US FAERS
111Deep Vein ThrombosisFAERS: 3US FAERS
112Delusional disorder, persecutory typeFAERS: 3OFFSIDES
US FAERS
113DiverticulitisFAERS: 3US FAERS
114Drug dose omissionFAERS: 3US FAERS
115DysmorphismFAERS: 3US FAERS
116Epstein Barr virus positive mucocutaneous ulcerFAERS: 3US FAERS
117Exposure via body fluidFAERS: 3US FAERS
118Extremity necrosisFAERS: 3OFFSIDES
US FAERS
119General physical condition abnormalFAERS: 3US FAERS
120HerniaFAERS: 3US FAERS
121Histiocytosis haematophagicFAERS: 3US FAERS
122Incorrect dose administeredFAERS: 3US FAERS
123Joint swellingFAERS: 3US FAERS
124Low birth weight babyFAERS: 3US FAERS
125MacrocytosisFAERS: 3OFFSIDES
US FAERS
126MalariaFAERS: 3US FAERS
127Memory impairmentFAERS: 3US FAERS
128MyelofibrosisFAERS: 3US FAERS
129Oropharyngeal painFAERS: 3US FAERS
130Pancreatic carcinomaFAERS: 3US FAERS
131PolyhydramniosFAERS: 3US FAERS
132PolyneuropathyFAERS: 3US FAERS
133Premature MenopauseFAERS: 3US FAERS
134Prescribed overdoseFAERS: 3US FAERS
135Product counterfeitFAERS: 3US FAERS
136Product storage errorFAERS: 3US FAERS
137Pulmonary HypertensionFAERS: 3OFFSIDES
US FAERS
138Pyoderma GangrenosumFAERS: 3OFFSIDES
US FAERS
139Rheumatoid ArthritisFAERS: 3US FAERS
140SarcomaFAERS: 3US FAERS
141Skin lesionFAERS: 3US FAERS
142Sperm concentration decreasedFAERS: 3US FAERS
143Spermatozoa morphology abnormalFAERS: 3US FAERS
144Suicide attemptFAERS: 3US FAERS
145SyncopeFAERS: 3US FAERS
146VertigoFAERS: 3US FAERS
147treatment failureFAERS: 3US FAERS
148Activities of daily living impairedFAERS: 2US FAERS
149Acute kidney injuryFAERS: 2US FAERS
150AgeusiaFAERS: 2US FAERS
151AgranulocytosisFAERS: 2US FAERS
152AlveolitisFAERS: 2US FAERS
153Amyotrophic Lateral SclerosisFAERS: 2US FAERS
154Blast cells presentFAERS: 2US FAERS
155BlindnessFAERS: 2US FAERS
156Blood urea increasedFAERS: 2OFFSIDES
SIDER
US FAERS
157Bone painFAERS: 2US FAERS
158Chest PainFAERS: 2US FAERS
159Coagulation factor V level decreasedFAERS: 2US FAERS
160ColitisFAERS: 2US FAERS
161Craniofacial deformityFAERS: 2US FAERS
162CryotherapyFAERS: 2US FAERS
163DeafnessFAERS: 2US FAERS
164Diabetes MellitusFAERS: 2US FAERS
165Disseminated Intravascular CoagulationFAERS: 2US FAERS
166Drug exposure during pregnancyFAERS: 2OFFSIDES
US FAERS
167Drug ineffective for unapproved indicationFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
168Drug prescribing errorFAERS: 2US FAERS
169EczemaFAERS: 2US FAERS
170Erectile dysfunctionFAERS: 2US FAERS
171Escherichia infectionFAERS: 2US FAERS
172Febrile NeutropeniaFAERS: 2OFFSIDES
SIDER
US FAERS
173GastrectomyFAERS: 2US FAERS
174Hepatitis BFAERS: 2US FAERS
175HepatotoxicityFAERS: 2OFFSIDES
SIDER
US FAERS
176HoloprosencephalyFAERS: 2US FAERS
177HyperkeratosisFAERS: 2US FAERS
178Incorrect product storageFAERS: 2US FAERS
179InfertilityFAERS: 2US FAERS
180Intentional product use issueFAERS: 2US FAERS
181Intestinal PerforationFAERS: 2US FAERS
182LacerationFAERS: 2US FAERS
183LethargyFAERS: 2US FAERS
184Live BirthFAERS: 2US FAERS
185LymphadenopathyFAERS: 2US FAERS
186Medication ErrorFAERS: 2US FAERS
187Mole excisionFAERS: 2US FAERS
188Mycosis FungoidesFAERS: 2US FAERS
189Myelodysplastic syndrome transformationFAERS: 2OFFSIDES
US FAERS
190NephrolithiasisFAERS: 2US FAERS
191Neutrophil count decreasedFAERS: 2OFFSIDES
US FAERS
192Occupational exposure to productFAERS: 2US FAERS
193OligohydramniosFAERS: 2US FAERS
194Oral painFAERS: 2US FAERS
195Oropharyngeal blisteringFAERS: 2US FAERS
196OsteomyelitisFAERS: 2US FAERS
197Pharmaceutical product complaintFAERS: 2US FAERS
198PleurisyFAERS: 2OFFSIDES
US FAERS
199Poor quality sleepFAERS: 2US FAERS
200PorokeratosisFAERS: 2US FAERS
201Portal hypertensive gastropathyFAERS: 2US FAERS
202Product friableFAERS: 2US FAERS
203PseudohyperkalaemiaFAERS: 2US FAERS
204Pulmonary malformationFAERS: 2US FAERS
205Raoultella ornithinolytica infectionFAERS: 2US FAERS
206Rash erythematousFAERS: 2US FAERS
207SarcoidosisFAERS: 2OFFSIDES
US FAERS
208ScabFAERS: 2US FAERS
209Spinal column stenosisFAERS: 2US FAERS
210SuperinfectionFAERS: 2US FAERS
211Suspected counterfeit productFAERS: 2US FAERS
212Therapeutic procedureFAERS: 2US FAERS
213Tongue pigmentationFAERS: 2US FAERS
214Urinary IncontinenceFAERS: 2US FAERS
215Urinary tract infectionFAERS: 2US FAERS
216Venous InsufficiencyFAERS: 2OFFSIDES
US FAERS
217VitiligoFAERS: 2US FAERS
218Abdominal AbscessFAERS: 1US FAERS
219Abdominal hernia obstructiveFAERS: 1US FAERS
220AbscessFAERS: 1US FAERS
221Accidental exposure to productFAERS: 1US FAERS
222Acquired mitochondrial DNA mutationFAERS: 1US FAERS
223Acute Chest SyndromeFAERS: 1OFFSIDES
US FAERS
224AgitationFAERS: 1US FAERS
225Alanine Aminotransferase IncreasedFAERS: 1OFFSIDES
US FAERS
226Altered state of consciousnessFAERS: 1US FAERS
227Animal biteFAERS: 1US FAERS
228AnosmiaFAERS: 1US FAERS
229AnxietyFAERS: 1US FAERS
230Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
231AsphyxiaFAERS: 1OFFSIDES
US FAERS
232Aspiration bone marrow abnormalFAERS: 1US FAERS
233AsthmaFAERS: 1US FAERS
234Atrioventricular BlockFAERS: 1US FAERS
235BacteriuriaFAERS: 1US FAERS
236BiopsyFAERS: 1US FAERS
237Bladder NeoplasmFAERS: 1US FAERS
238Blast cell count increasedFAERS: 1OFFSIDES
US FAERS
239Blood cholesterol increasedFAERS: 1US FAERS
240Blood creatine phosphokinase increasedFAERS: 1US FAERS
241Blood folate decreasedFAERS: 1US FAERS
242Blood glucose decreasedFAERS: 1US FAERS
243Blood homocysteine increasedFAERS: 1US FAERS
244Blood iron increasedFAERS: 1OFFSIDES
US FAERS
245Blood magnesium increasedFAERS: 1OFFSIDES
US FAERS
246Blood phosphorus increasedFAERS: 1OFFSIDES
US FAERS
247Blood potassium decreasedFAERS: 1US FAERS
248Blood potassium increasedFAERS: 1OFFSIDES
US FAERS
249Blood sodium decreasedFAERS: 1US FAERS
250Blood thyroid stimulating hormone decreasedFAERS: 1US FAERS
251Blood urine presentFAERS: 1US FAERS
252BronchopneumopathyFAERS: 1US FAERS
253BronchospasmFAERS: 1US FAERS
254Capillary FragilityFAERS: 1US FAERS
255Capsule physical issueFAERS: 1US FAERS
256Cardiac ArrestFAERS: 1US FAERS
257Cardiac neoplasm unspecifiedFAERS: 1US FAERS
258Cartilage injuryFAERS: 1US FAERS
259CataractFAERS: 1US FAERS
260Central nervous system lesionFAERS: 1US FAERS
261ChokingFAERS: 1US FAERS
262CholelithiasisFAERS: 1US FAERS
263CholestasisFAERS: 1US FAERS
264ChromaturiaFAERS: 1US FAERS
265Clostridium difficile colitisFAERS: 1US FAERS
266Colon cancer recurrentFAERS: 1US FAERS
267Complication associated with deviceFAERS: 1US FAERS
268Corneal OpacityFAERS: 1US FAERS
269Coronary Artery DiseaseFAERS: 1US FAERS
270Creatinine renal clearance decreasedFAERS: 1US FAERS
271Cyst removalFAERS: 1US FAERS
272CystitisFAERS: 1US FAERS
273CytopeniaFAERS: 1US FAERS
274DehydrationFAERS: 1US FAERS
275DeliriumFAERS: 1US FAERS
276Depressed moodFAERS: 1US FAERS
277Device malfunctionFAERS: 1US FAERS
278Diffuse Large B-Cell LymphomaFAERS: 1US FAERS
279DiscomfortFAERS: 1SIDER
US FAERS
280Drug dispensing errorFAERS: 1US FAERS
281Drug monitoring procedure incorrectly performedFAERS: 1US FAERS
282Drug resistanceFAERS: 1OFFSIDES
US FAERS
283Drug screen positiveFAERS: 1US FAERS
284Drug withdrawal syndromeFAERS: 1US FAERS
285Dry gangreneFAERS: 1US FAERS
286Duodenal UlcerFAERS: 1US FAERS
287DysgeusiaFAERS: 1US FAERS
288DysgraphiaFAERS: 1OFFSIDES
US FAERS
289DysphoniaFAERS: 1US FAERS
290Early satietyFAERS: 1US FAERS
291ElectrocoagulationFAERS: 1US FAERS
292Electrolyte imbalanceFAERS: 1US FAERS
293EmbolismFAERS: 1OFFSIDES
US FAERS
294Emotional disorderFAERS: 1US FAERS
295Exposure via fatherFAERS: 1US FAERS
296Eye irritationFAERS: 1US FAERS
297Eye painFAERS: 1US FAERS
298Feeding tube userFAERS: 1US FAERS
299Feeling abnormalFAERS: 1SIDER
US FAERS
300FlushingFAERS: 1US FAERS
301Forceps deliveryFAERS: 1US FAERS
302Full blood count decreasedFAERS: 1US FAERS
303Full blood count increasedFAERS: 1US FAERS
304GangreneFAERS: 1OFFSIDES
SIDER
US FAERS
305Gastric infectionFAERS: 1US FAERS
306GastrostomyFAERS: 1US FAERS
307Gene MutationFAERS: 1US FAERS
308GlioblastomaFAERS: 1US FAERS
309GlossitisFAERS: 1US FAERS
310GoutFAERS: 1US FAERS
311GranulomaFAERS: 1US FAERS
312HaematotoxicityFAERS: 1US FAERS
313Hepatitis B virus test positiveFAERS: 1US FAERS
314Human papilloma virus test positiveFAERS: 1US FAERS
315HydronephrosisFAERS: 1US FAERS
316Hyperkeratosis palmaris and plantarisFAERS: 1US FAERS
317HyperthyroidismFAERS: 1US FAERS
318HypertrichosisFAERS: 1US FAERS
319Hyperviscosity syndromeFAERS: 1US FAERS
320HypoperfusionFAERS: 1US FAERS
321HypotensionFAERS: 1US FAERS
322HypothyroidismFAERS: 1US FAERS
323HysterectomyFAERS: 1US FAERS
324Idiopathic Pulmonary FibrosisFAERS: 1US FAERS
325IleusFAERS: 1US FAERS
326Immune thrombocytopenic purpuraFAERS: 1US FAERS
327Impaired self-careFAERS: 1US FAERS
328Inappropriate schedule of drug administrationFAERS: 1US FAERS
329Inappropriate schedule of product administrationFAERS: 1US FAERS
330IncontinenceFAERS: 1US FAERS
331Incorrect drug administration durationFAERS: 1US FAERS
332Incorrect route of drug administrationFAERS: 1US FAERS
333Incorrect route of product administrationFAERS: 1US FAERS
334Increased tendency to bruiseFAERS: 1US FAERS
335Intellectual DisabilityFAERS: 1US FAERS
336Intentional product misuseFAERS: 1US FAERS
337Intentional self-injuryFAERS: 1US FAERS
338JC virus infectionFAERS: 1US FAERS
339Joint injuryFAERS: 1US FAERS
340Keratosis pilarisFAERS: 1US FAERS
341Lactose IntoleranceFAERS: 1OFFSIDES
US FAERS
342LaryngotracheitisFAERS: 1US FAERS
343LeprosyFAERS: 1US FAERS
344LeukapheresisFAERS: 1US FAERS
345Leukocytoclastic vasculitisFAERS: 1US FAERS
346LeukoencephalopathyFAERS: 1US FAERS
347Light chain analysis increasedFAERS: 1US FAERS
348Limb discomfortFAERS: 1US FAERS
349Limb operationFAERS: 1US FAERS
350Lip swellingFAERS: 1US FAERS
351Loose toothFAERS: 1US FAERS
352Macular degenerationFAERS: 1US FAERS
353MarasmusFAERS: 1US FAERS
354Meconium Aspiration SyndromeFAERS: 1US FAERS
355Mental RetardationFAERS: 1US FAERS
356Mental status changesFAERS: 1OFFSIDES
US FAERS
357Metabolic acidosisFAERS: 1US FAERS
358Multiple MyelomaFAERS: 1US FAERS
359Multiple allergiesFAERS: 1US FAERS
360Muscle FatigueFAERS: 1US FAERS
361Muscle fibrosisFAERS: 1US FAERS
362Musculoskeletal PainFAERS: 1US FAERS
363Musculoskeletal chest painFAERS: 1US FAERS
364Musculoskeletal stiffnessFAERS: 1OFFSIDES
US FAERS
365MyocarditisFAERS: 1US FAERS
366MyositisFAERS: 19796402
12894095
CTD
US FAERS
367NecrosisFAERS: 1US FAERS
368Neonatal aspirationFAERS: 1US FAERS
369Nephrotic SyndromeFAERS: 1US FAERS
370NeuralgiaFAERS: 1US FAERS
371Neuropathic painFAERS: 1US FAERS
372NeuropathyFAERS: 1US FAERS
373Neutropenic sepsisFAERS: 1OFFSIDES
US FAERS
374Night sweatsFAERS: 1US FAERS
375OnychoclasisFAERS: 1US FAERS
376OnycholysisFAERS: 1US FAERS
377Open woundFAERS: 1US FAERS
378Optic AtrophyFAERS: 1US FAERS
379Oral candidiasisFAERS: 1US FAERS
380Pain of skinFAERS: 1US FAERS
381PallorFAERS: 1US FAERS
382PanniculitisFAERS: 1OFFSIDES
US FAERS
383Paternal exposure timing unspecifiedFAERS: 1US FAERS
384Peripheral swellingFAERS: 1US FAERS
385PetechiaeFAERS: 1US FAERS
386PharyngitisFAERS: 1US FAERS
387Pharyngolaryngeal PainFAERS: 1US FAERS
388Philadelphia chromosome positiveFAERS: 1US FAERS
389PhotodermatosisFAERS: 1US FAERS
390Platelet TransfusionFAERS: 1US FAERS
391Pneumococcal sepsisFAERS: 1US FAERS
392PoisoningFAERS: 1SIDER
US FAERS
393Portal Vein ThrombosisFAERS: 1OFFSIDES
US FAERS
394Posterior reversible encephalopathy syndromeFAERS: 1US FAERS
395Postoperative wound complicationFAERS: 1US FAERS
396Pre-EclampsiaFAERS: 1OFFSIDES
US FAERS
397Precancerous skin lesionFAERS: 1US FAERS
398Product dosage form issueFAERS: 1US FAERS
399Product formulation issueFAERS: 1US FAERS
400Product preparation errorFAERS: 1US FAERS
401Product prescribing errorFAERS: 1US FAERS
402Product size issueFAERS: 1US FAERS
403ProteinuriaFAERS: 1US FAERS
404PsoriasisFAERS: 1

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CTD
US FAERS
405Pulmonary toxicityFAERS: 1US FAERS
406Quality of life decreasedFAERS: 1US FAERS
407Red blood cell burr cells presentFAERS: 1US FAERS
408Red blood cell schistocytes presentFAERS: 1US FAERS
409Renal Cell CarcinomaFAERS: 1US FAERS
410Renal tubular acidosisFAERS: 1OFFSIDES
US FAERS
411Renal tubular disorderFAERS: 1US FAERS
412Respiratory distressFAERS: 1US FAERS
413Restless Legs SyndromeFAERS: 1US FAERS
414RetchingFAERS: 1US FAERS
415RhabdomyolysisFAERS: 1US FAERS
416Right ventricular failureFAERS: 1US FAERS
417ScleremaFAERS: 1US FAERS
418Scleroderma-like reactionFAERS: 1US FAERS
419ScreamingFAERS: 1US FAERS
420Severe Acute Respiratory SyndromeFAERS: 1OFFSIDES
US FAERS
421Silent myocardial infarctionFAERS: 1US FAERS
422Sinus operationFAERS: 1US FAERS
423SinusitisFAERS: 1US FAERS
424Sjogren's SyndromeFAERS: 1US FAERS
425Skin ErosionFAERS: 1US FAERS
426Skin irritationFAERS: 1US FAERS
427SomnolenceFAERS: 1SIDER
US FAERS
428Spermatozoa progressive motility decreasedFAERS: 1US FAERS
429StressFAERS: 1US FAERS
430TeratomaFAERS: 1US FAERS
431Therapy non-responderFAERS: 1OFFSIDES
US FAERS
432Thoracic Outlet SyndromeFAERS: 1US FAERS
433TonsillectomyFAERS: 1US FAERS
434Tooth ExtractionFAERS: 1OFFSIDES
US FAERS
435Tooth LossFAERS: 1US FAERS
436ToothacheFAERS: 1US FAERS
437Transaminases increasedFAERS: 1US FAERS
438Treponema test positiveFAERS: 1US FAERS
439Upper respiratory tract inflammationFAERS: 1US FAERS
440Urethral StenosisFAERS: 1US FAERS
441Vascular purpuraFAERS: 1US FAERS
442Vasculitic rashFAERS: 1US FAERS
443Venous thrombosis limbFAERS: 1US FAERS
444Ventricular DysfunctionFAERS: 1US FAERS
445Ventricular FibrillationFAERS: 1US FAERS
446Visual ImpairmentFAERS: 1US FAERS
447Vulvovaginal pruritusFAERS: 1US FAERS
448Weaning failureFAERS: 1US FAERS
449Wheelchair userFAERS: 1US FAERS
450WheezingFAERS: 1US FAERS
451Wound InfectionFAERS: 1US FAERS
452Wrong drug administeredFAERS: 1US FAERS
453XerosisFAERS: 1US FAERS
454cancer surgeryFAERS: 1US FAERS
455keratoacanthomaFAERS: 1US FAERS
456nervous system disorderFAERS: 1SIDER
US FAERS
457skin abrasionFAERS: 1US FAERS
458AbasiaOFFSIDES
459Abdominal adhesionsOFFSIDES
460Abnormal visionOFFSIDES
461Abnormalities, Drug-Induced4012644CTD
462AdenitisOFFSIDES
463Adenocarcinoma1142528CTD
OFFSIDES
464AdenomaOFFSIDES
465Albuminuria24084325CTD
466AmenorrheaOFFSIDES
467Anaplastic astrocytomaOFFSIDES
468Anemia, Hemolytic15558807CTD
469Anemia, Macrocytic4726895
5120187
10606163
CTD
470Anemia, Sickle Cell

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CTD
471Anemia

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CTD
472AnhedoniaOFFSIDES
473AnisocytosisOFFSIDES
474Ankle FractureOFFSIDES
475Anticholinergic SyndromeOFFSIDES
476Anticonvulsant drug level decreasedOFFSIDES
477AnuriaOFFSIDES
478AphagiaSIDER
479AppendectomyOFFSIDES
480ArteriosclerosisOFFSIDES
481AscitesOFFSIDES
482AtaxiaOFFSIDES
483AtelectasisOFFSIDES
484Atrial FlutterOFFSIDES
485Avascular necrosisOFFSIDES
486Bacteria blood identifiedOFFSIDES
487Bacterial EndocarditisOFFSIDES
488Basophil percentage decreasedOFFSIDES
489Behcet Syndrome11426495
16440777
CTD
490BicytopeniaOFFSIDES
491Biliary dilatationOFFSIDES
492Bilirubin conjugated increasedOFFSIDES
493Blast cell count decreasedOFFSIDES
494BlepharitisSIDER
495BlepharoptosisOFFSIDES
496Blood and lymphatic system disordersSIDER
497Blood chloride increasedOFFSIDES
498Blood iron decreasedCanada Vigilance: 1Canada Vigilance
SIDER
499Blood phosphorus decreasedOFFSIDES
500Blood potassiumOFFSIDES
501Blood uric acidOFFSIDES
502Body TemperatureOFFSIDES
503Bone marrow depressionSIDER
504Brain Diseases1168328CTD
505Bronchoalveolar LavageOFFSIDES
506Campylobacter infectionOFFSIDES
507Cardiac TamponadeOFFSIDES
508Catheter related infectionOFFSIDES
509Cerebral ventricle dilatationOFFSIDES
510Chemical and Drug Induced Liver Injury28437613CTD
511CholangiolitisOFFSIDES
512CholecystitisOFFSIDES
513Choroidal DetachmentOFFSIDES
514Chromosome Breakage23573231CTD
515Chronic ulcerative colitisOFFSIDES
516Clonal EvolutionOFFSIDES
517Colonic Neoplasms2932908CTD
518Compression fractureOFFSIDES
519ConstipationSIDER
520Coronary artery insufficiencyOFFSIDES
521Creatinine increasedSIDER
522Culture positiveOFFSIDES
523Cytolytic hepatitisOFFSIDES
524Dacryostenosis acquiredOFFSIDES
525Dental prosthesis placementOFFSIDES
526Dermatitis7499134CTD
SIDER
527DermatophytosisOFFSIDES
528Device interactionOFFSIDES
529Diarrhea12620292CTD
OFFSIDES
530Disease ProgressionOFFSIDES
531Disease complicationOFFSIDES
532DistressSIDER
533Dreamy stateOFFSIDES
534DrowsinessSIDER
535Drug Eruptions19784527CTD
536Drug ToleranceOFFSIDES
537Drug exposure before pregnancyOFFSIDES
538Drug exposure via breast milkOFFSIDES
539Drug level below therapeuticOFFSIDES
540Drug withdrawal headacheOFFSIDES
541DyspepsiaSIDER
542DysuriaSIDER
543Ectromelia15772364CTD
544EctropionOFFSIDES
545Edema22898132CTD
546Embryo Loss22898132CTD
547Emotional distressSIDER
548Endodontic procedureOFFSIDES
549Enterobacter sepsisOFFSIDES
550EnterocolitisOFFSIDES
551Epidermal necrosisOFFSIDES
552Epigastric discomfortSIDER
553Erythema InfectiosumSIDER
554Erythema NodosumOFFSIDES
555ErythromelalgiaOFFSIDES
556Escherichia sepsisOFFSIDES
557Esophageal StenosisOFFSIDES
558Fatty LiverOFFSIDES
559Febrile infectionOFFSIDES
560Feeding and Eating Disorders4883783CTD
561Fluid overloadOFFSIDES
562Folic Acid Deficiency5120187CTD
563Foot Ulcer

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CTD
564Fungus stool identifiedOFFSIDES
565Gastric irritationSIDER
566GastrinomaOFFSIDES
567Gastrointestinal Hemorrhage16398570CTD
568Gastrointestinal hypermotilityOFFSIDES
569Gastrointestinal hypomotilityOFFSIDES
570Gastrointestinal inflammationOFFSIDES
571Gastrointestinal obstructionOFFSIDES
572Gastrointestinal ulcerSIDER
573Gene mutation identification testOFFSIDES
574Glioblastoma MultiformeOFFSIDES
575GlobulinuriaOFFSIDES
576GranulocytosisOFFSIDES
577Growth Disorders22898132CTD
578HIV Infections

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CTD
579Hand Dermatoses9692318CTD
580Head BangingOFFSIDES
581Head and Neck Neoplasms5775014CTD
582Hepatic InsufficiencySIDER
583Hepatic Vein ThrombosisOFFSIDES
584Hepatitis AOFFSIDES
585Hepatojugular refluxOFFSIDES
586HepatosplenomegalyOFFSIDES
587HydrocephalusOFFSIDES
588HydropneumothoraxOFFSIDES
589HydrothoraxOFFSIDES
590HypercapniaOFFSIDES
591Hyperpigmentation4643395
7499134
9256830
CTD
592HypersplenismSIDER
593HypokinesiaOFFSIDES
594Hyponatremia15103940CTD
595HypophagiaCanada Vigilance: 1Canada Vigilance
596HypospadiasOFFSIDES
597HypoxiaOFFSIDES
598Ileal StenosisOFFSIDES
599ImmunosuppressionOFFSIDES
600Incision site complicationOFFSIDES
601Incision site erythemaOFFSIDES
602InfestationSIDER
603InflammationCanada Vigilance: 1Canada Vigilance
604Injury asphyxiationOFFSIDES
605IntoxicationSIDER
606IntubationOFFSIDES
607Iron OverloadOFFSIDES
608Keratitis siccaOFFSIDES
609Keratoderma, Palmoplantar8763456CTD
610Kidney Diseases9256830CTD
611Kidney FailureOFFSIDES
612Left ventricular end-diastolic pressure increasedOFFSIDES
613Leg Ulcer

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CTD
SIDER
614Leukemia secondarySIDER
615Leukopenia neonatalOFFSIDES
616LeukostasisOFFSIDES
617Lichen PlanusOFFSIDES
618Limb Deformities, Congenital23696560CTD
619Lipodystrophy acquiredOFFSIDES
620ListeriosisOFFSIDES
621Liver Neoplasms, Experimental8093813CTD
622LividityOFFSIDES
623Localised intraabdominal fluid collectionOFFSIDES
624Lupus ErythematosusSIDER
625LymphedemaOFFSIDES
626Lymphocyte count decreasedOFFSIDES
627Mallory-Weiss SyndromeOFFSIDES
628Mastication disorderOFFSIDES
629MegacolonOFFSIDES
630MelanonychiaSIDER
631Metastatic NeoplasmSIDER
632MicrocytosisOFFSIDES
633Micronuclei, Chromosome-Defective24211769CTD
634Mitral Valve StenosisOFFSIDES
635Monocyte percentage decreasedOFFSIDES
636MononeuritisOFFSIDES
637Myelocyte count decreasedOFFSIDES
638MyelocytosisOFFSIDES
639MyelodysplasiaOFFSIDES
640MyelosuppressionSIDER
641MyopiaOFFSIDES
642Nail Diseases9256830CTD
643Nasal discomfortOFFSIDES
644Nephritis, Interstitial9221195CTD
645Nephrogenic Fibrosing DermopathyOFFSIDES
646Neural Tube Defects4012644
25527867
CTD
647Neurologic Manifestations10465092CTD
648Obesity surgeryOFFSIDES
649Ocular ToxicityOFFSIDES
650Ocular icterusOFFSIDES
651OligospermiaSIDER
652Open reduction of fractureOFFSIDES
653OphthalmoplegiaOFFSIDES
654Oral Ulcer11177373CTD
655Oral mucosal hypertrophyOFFSIDES
656Oral polypectomyOFFSIDES
657Oropharyngitis fungalOFFSIDES
658Osteitis DeformansOFFSIDES
659OsteopeniaOFFSIDES
660OsteoporosisOFFSIDES
661Pancreatic PseudocystOFFSIDES
662PapuleSIDER
663ParacentesisOFFSIDES
664ParaparesisOFFSIDES
665Paroxysmal arrhythmiaOFFSIDES
666Pelvic abscessOFFSIDES
667Performance status decreasedOFFSIDES
668Perianal abscessOFFSIDES
669PeriarthritisOFFSIDES
670Pericardial effusionOFFSIDES
671PericarditisOFFSIDES
672Peripheral Nervous System Diseases10716503
10716516
CTD
673Pigmentation Disorders12894095CTD
674Polycythemia Vera

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CTD
675Porphyria non-acuteOFFSIDES
676Post inflammatory pigmentation changeOFFSIDES
677Postoperative abscessOFFSIDES
678Prenatal Injuries25527867CTD
679Primary Myelofibrosis8638610CTD
680Prolapse repairOFFSIDES
681Promyelocyte count decreasedOFFSIDES
682Prostatic Neoplasms1142528CTD
683Protein total increasedOFFSIDES
684Prothrombin level abnormalOFFSIDES
685Prothrombin level decreasedOFFSIDES
686Pseudomonal sepsisOFFSIDES
687Pseudomyxoma PeritoneiOFFSIDES
688Pulmonary arterial hypertensionOFFSIDES
689Pulmonary vasculitisOFFSIDES
690Purulent dischargeOFFSIDES
691Radiation associated painOFFSIDES
692Radiation injurySIDER
693Radiation mucositisOFFSIDES
694Radiation skin injurySIDER
695RalesOFFSIDES
696Raynaud Disease6846998
12620292
CTD
697Recall phenomenonSIDER
698Rectal ProlapseOFFSIDES
699Red blood cell sickled cells presentOFFSIDES
700Red man syndromeOFFSIDES
701Reticulocyte count increasedOFFSIDES
702ReticulocytopeniaSIDER
703Rheumatoid factor increasedOFFSIDES
704RhonchiOFFSIDES
705Septic ShockOFFSIDES
706SeromaOFFSIDES
707Sinus bradycardiaOFFSIDES
708Skin IndurationOFFSIDES
709Skin Neoplasms20231502CTD
710Skin hypertrophyOFFSIDES
711Skin neoplasm excisionOFFSIDES
712Skin tightnessOFFSIDES
713Skin toxicityOFFSIDES
714SplenectomyOFFSIDES
715Splenic sequestrationSIDER
716Stem cell transplantOFFSIDES
717StridorOFFSIDES
718T-Cell LymphomaOFFSIDES
719Temperature intoleranceOFFSIDES
720Teratogenesis22898132
23696560
CTD
721Therapeutic response changedCanada Vigilance: 1Canada Vigilance
722Therapeutic response unexpectedOFFSIDES
723Thoracic cavity drainageOFFSIDES
724Thrombocythemia, Essential

View details

CTD
725Thromboembolism19636672CTD
726Tongue blisteringCanada Vigilance: 1Canada Vigilance
727Tooth InfectionOFFSIDES
728Transfusion ReactionOFFSIDES
729Transmission of drug via semenOFFSIDES
730Tumor Lysis Syndrome12708945CTD
731Varicose Ulcer19810313CTD
732Vascular Diseases14965870CTD
733Vascular calcificationOFFSIDES
734Viral pericarditisOFFSIDES
735Vitreous DetachmentOFFSIDES
736bone marrow fibrosisOFFSIDES
737effusionOFFSIDES
738jaundiceCanada Vigilance: 2Canada Vigilance
739leukemia4883783
11317962
17686055
CTD
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