MetaADEDB 2.0 @ LMMD
cefditoren pivoxil
(AFZFFLVORLEPPO-UVYJNCLZSA-N)
Structure
SMILES
CO/N=C(/c1csc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)OCOC(=O)C(C)(C)C)/C=C\c1scnc1C
Molecular Formula:
C25H28N6O7S3
Molecular Weight:
620.721
Log P:
3.2081
Hydrogen Bond Acceptor:
16
Hydrogen Bond Donor:
2
TPSA:
257.18
CAS Number(s):
117467-28-4
Synonym(s)
1.
cefditoren pivoxil
2.
(-)-(6R,7R)-2,2-dimethylpropionyloxymethyl 7-((Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido)-3-((Z)-2-(4-methylthiazol-5-yl)ethenyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate
3.
7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(2-(4-methylthiazol-5-yl)ethenyl)cephem-4-carboxylic acid pivaloyloxymethyl ester
4.
CDTR-PI
5.
ME 1207
6.
ME-1207
7.
Spectracef
External Link(s)
MeSHC057710
PubChem Compound6437877
ChEBI560555
CHEMBLCHEMBL454446
DrugCentral534
KEGGdr:D01628
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 37OFFSIDES
US FAERS
2Clostridium colitisFAERS: 36OFFSIDES
US FAERS
3NauseaFAERS: 26US FAERS
4Abdominal PainFAERS: 20OFFSIDES
US FAERS
5DyspepsiaFAERS: 14OFFSIDES
US FAERS
6UrticariaFAERS: 13US FAERS
7Drug ineffective for unapproved indicationFAERS: 11US FAERS
8HypersensitivityFAERS: 11US FAERS
9Abdominal discomfortFAERS: 7US FAERS
10PruritusFAERS: 7US FAERS
11AnorexiaFAERS: 6US FAERS
12DehydrationFAERS: 6OFFSIDES
US FAERS
13PneumoniaFAERS: 612501878
12501879
CTD
US FAERS
14VomitingFAERS: 6US FAERS
15CellulitisFAERS: 4OFFSIDES
US FAERS
16HeadacheFAERS: 4US FAERS
17Carnitine decreasedFAERS: 3OFFSIDES
US FAERS
18Chest discomfortFAERS: 3US FAERS
19ColitisFAERS: 3US FAERS
20DizzinessFAERS: 3US FAERS
21Altered state of consciousnessFAERS: 2US FAERS
22Bacteria stool identifiedFAERS: 2US FAERS
23Blood urea increasedFAERS: 2US FAERS
24CandidiasisFAERS: 2US FAERS
25Carnitine deficiencyFAERS: 2US FAERS
26Disease recurrenceFAERS: 2US FAERS
27ErythemaFAERS: 2US FAERS
28HepatitisFAERS: 2OFFSIDES
US FAERS
29MalaiseFAERS: 2US FAERS
30Oral candidiasisFAERS: 2US FAERS
31PalpitationsFAERS: 2US FAERS
32SomnolenceFAERS: 2US FAERS
33Stevens-Johnson SyndromeFAERS: 2US FAERS
34SwellingFAERS: 2US FAERS
35TremorFAERS: 2US FAERS
36AbscessFAERS: 1US FAERS
37AgnosiaFAERS: 1US FAERS
38Ammonia increasedFAERS: 1OFFSIDES
US FAERS
39ArthritisFAERS: 1US FAERS
40AstheniaFAERS: 1US FAERS
41Autoimmune neutropeniaFAERS: 1US FAERS
42Blood creatine abnormalFAERS: 1US FAERS
43Blood creatinine increasedFAERS: 1US FAERS
44Blood glucose decreasedFAERS: 1US FAERS
45Blood glucose increasedFAERS: 1US FAERS
46BronchitisFAERS: 1US FAERS
47Burning sensationFAERS: 1US FAERS
48Cardiac ArrestFAERS: 1US FAERS
49Catheter related infectionFAERS: 1US FAERS
50Central nervous system lesionFAERS: 1US FAERS
51CholecystitisFAERS: 1US FAERS
52CholelithiasisFAERS: 1US FAERS
53ConstipationFAERS: 1US FAERS
54Coronary Artery DiseaseFAERS: 1US FAERS
55CyanosisFAERS: 1US FAERS
56DysgeusiaFAERS: 1US FAERS
57Electroencephalogram abnormalFAERS: 1US FAERS
58Emotional distressFAERS: 1US FAERS
59Enterococcal infectionFAERS: 1US FAERS
60Enterocolitis viralFAERS: 1OFFSIDES
US FAERS
61EpistaxisFAERS: 1US FAERS
62Erectile dysfunctionFAERS: 1US FAERS
63Erythema MultiformeFAERS: 1US FAERS
64Facial PainFAERS: 1US FAERS
65Feeling ColdFAERS: 1US FAERS
66FlatulenceFAERS: 1US FAERS
67HemiparesisFAERS: 1US FAERS
68Hemisensory NeglectFAERS: 1US FAERS
69HypercapniaFAERS: 1US FAERS
70Lactose IntoleranceFAERS: 1US FAERS
71LaryngospasmFAERS: 1US FAERS
72LethargyFAERS: 1US FAERS
73Lip exfoliationFAERS: 1US FAERS
74Lip swellingFAERS: 1US FAERS
75Medication ErrorFAERS: 1US FAERS
76Mental impairmentFAERS: 1US FAERS
77Mental status changesFAERS: 1US FAERS
78Metabolic acidosisFAERS: 1US FAERS
79MetrorrhagiaFAERS: 1US FAERS
80Myocardial InfarctionFAERS: 1US FAERS
81MyocarditisFAERS: 1US FAERS
82Oculomucocutaneous syndromeFAERS: 1US FAERS
83Oropharyngeal swellingFAERS: 1US FAERS
84PainFAERS: 1US FAERS
85PallorFAERS: 1OFFSIDES
US FAERS
86ParanoiaFAERS: 1US FAERS
87PolyarthritisFAERS: 1US FAERS
88Serum SicknessFAERS: 1US FAERS
89Serum sickness-like reactionFAERS: 1US FAERS
90Sudden deathFAERS: 1US FAERS
91TachycardiaFAERS: 1US FAERS
92Therapy non-responderFAERS: 1US FAERS
93ThrombocytopeniaFAERS: 1US FAERS
94Urinary tract infectionFAERS: 1US FAERS
95Ventricular hypertrophyFAERS: 1US FAERS
96Visual ImpairmentFAERS: 1US FAERS
97jaundiceFAERS: 1US FAERS
98Abdominal massOFFSIDES
99AcneOFFSIDES
100AdenitisOFFSIDES
101ApathyOFFSIDES
102AppendicitisOFFSIDES
103AsthmaOFFSIDES
104Blood calcium abnormalOFFSIDES
105Blood creatine phosphokinase increasedOFFSIDES
106Blood lactate dehydrogenase increasedOFFSIDES
107Bronchitis, Chronic12501879CTD
108Carcinoembryonic antigen increasedOFFSIDES
109Cerebellar infarctionOFFSIDES
110CholangiolitisOFFSIDES
111Chronic sinusitisOFFSIDES
112Colonic StenosisOFFSIDES
113Community-Acquired Infections12501878
12501879
CTD
114Concomitant disease aggravatedOFFSIDES
115CryingOFFSIDES
116Culture wound positiveOFFSIDES
117Dental discomfortOFFSIDES
118Depressed Level of ConsciousnessOFFSIDES
119Diabetes InsipidusOFFSIDES
120DiarrheaOFFSIDES
121Diverticular fistulaOFFSIDES
122Diverticular perforationOFFSIDES
123DiverticulumOFFSIDES
124Dry skinOFFSIDES
125Electromechanical dissociationOFFSIDES
126Endodontic procedureOFFSIDES
127Endoscopy abnormalOFFSIDES
128EnterocolitisOFFSIDES
129Euphoric moodOFFSIDES
130Eustachian tube disorderOFFSIDES
131FasciitisOFFSIDES
132FibromyalgiaOFFSIDES
133Food PoisoningOFFSIDES
134Gastric Antral Vascular EctasiaOFFSIDES
135Gastric mucosal lesionOFFSIDES
136GastroenteritisOFFSIDES
137Gastrointestinal motility disorderOFFSIDES
138General physical health deteriorationOFFSIDES
139Haemophilus Infections12501879CTD
140Hay feverOFFSIDES
141HemiplegiaOFFSIDES
142High density lipoprotein increasedOFFSIDES
143HydronephrosisOFFSIDES
144Intervertebral Disc DegenerationOFFSIDES
145IritisOFFSIDES
146Loose toothOFFSIDES
147Lymphocyte count decreasedOFFSIDES
148Lymphocyte stimulation test positiveOFFSIDES
149Mixed liver injuryOFFSIDES
150MumpsOFFSIDES
151Muscle strainOFFSIDES
152Myoglobin blood increasedOFFSIDES
153MyringitisOFFSIDES
154NasopharyngitisOFFSIDES
155NoduleOFFSIDES
156Ocular icterusOFFSIDES
157Oropharyngeal painOFFSIDES
158Palpable purpuraOFFSIDES
159Pharyngitis12501879CTD
160Pharyngolaryngeal PainOFFSIDES
161Pneumococcal Infections12501879CTD
162Purulent dischargeOFFSIDES
163Relapsing FeverOFFSIDES
164Renal cystOFFSIDES
165Retinal VasculitisOFFSIDES
166Risus sardonicusOFFSIDES
167SchizophreniaOFFSIDES
168Skin WrinklingOFFSIDES
169Spinal fusion surgeryOFFSIDES
170Staphylococcal abscessOFFSIDES
171Streptococcal Infections12501878CTD
172Tinea crurisOFFSIDES
173Tooth ExtractionOFFSIDES
174Type III immune complex mediated reactionOFFSIDES
175Upper respiratory tract inflammationOFFSIDES
176Urine chloride decreasedOFFSIDES
177Urine sodium decreasedOFFSIDES
178Water IntoxicationOFFSIDES
179Wound InfectionOFFSIDES
180YawningOFFSIDES
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