MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Gastric outlet obstruction

(UMLS:C0162651)

Definition:: The hindering of output from the STOMACH into the SMALL INTESTINE. This obstruction may be of mechanical or functional origin such as EDEMA from PEPTIC ULCER; NEOPLASMS; FOREIGN BODIES; or AGING.
UMLS ID:: C0162651
MeSH ID:: D017219

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405.748.340

Synonym(s)

Gastric outlet obstruction

GASTRIC OUT LET OBSTRUCTION

GASTRIC OUTLET OBSTRUCTION

Gastric outflow obstruction

gastric outlet obstruction

gastric outlet; obstruction

obstruction; gastric outlet

Associated Drug(s)

	Name	Number of Reports	Data Source
1	rofecoxib	FAERS: 9	US FAERS
2	Cisapride	FAERS: 2	OFFSIDES US FAERS
3	Fentanyl	FAERS: 2	US FAERS
4	Teriparatide	FAERS: 1	US FAERS
5	gemcitabine	FAERS: 1	US FAERS
6	Capecitabine		OFFSIDES
7	Leucovorin		OFFSIDES
8	Salmeterol Xinafoate		OFFSIDES
9	Vitamin E Nicotinate		OFFSIDES
10	carbidopa, levodopa drug combination		OFFSIDES
11	etizolam		OFFSIDES
12	lormetazepam		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Gastric Dilatation	46.7%
2	Gastritis	44.4%
3	Duodenogastric Reflux	40.7%
4	Peptic Ulcer	40.7%
5	Zollinger-Ellison syndrome	34.8%
6	Achlorhydria	31.1%
7	Gastric Antral Vascular Ectasia	31.1%
8	Esophageal Diseases	31%
9	Gastroenteritis	31%
10	Intestinal Diseases	31%
11	Duodenal Ulcer	30.8%
12	Peptic Ulcer Perforation	30.8%
13	Gastric ulcer	30.8%
14	Gastroparesis	30.8%
15	Stomach Neoplasms	29.1%
16	Dysentery	26.7%
17	Enteritis	26.7%
18	Enterocolitis	26.7%
19	Esophagitis	26.7%
20	Inflammatory Bowel Diseases	26.7%
21	Colitis	23.1%
22	Proctitis	23.1%
23	Dumping Syndrome	22.8%
24	Duodenitis	22%
25	Ileitis	22%
26	Erosive Duodenitis	22%
27	Proctocolitis	21.7%
28	Gastrointestinal Neoplasms	20.7%
29	Gastrointestinal Hemorrhage	20.5%
30	Tuberculosis, Gastrointestinal	20.1%
31	Cecal Diseases	20%
32	Colonic Diseases	20%
33	Esophageal Stenosis	20%
34	Ileal Diseases	20%
35	Intestinal Obstruction	20%
36	Intestinal Perforation	20%
37	Jejunal Diseases	20%
38	Pneumatosis Cystoides Intestinalis	20%
39	Rectal Diseases	20%
40	Cronkhite-Canada Syndrome	20%
41	Intestinal Polyposis	20%
42	Crohn Disease	19.6%
43	Duodenal Obstruction	19.6%
44	Enterocolitis, Neutropenic	19.6%
45	Necrotizing Enterocolitis	19.6%
46	Intestinal Neoplasms	18.5%
47	Biliary Tract Diseases	18.5%
48	Liver diseases	18.5%
49	Pancreatic Diseases	18.5%
50	Pouchitis	18.1%
51	Colorectal Neoplasms	18%
52	Esophageal and Gastric Varices	17.8%
53	Appendicitis	17.4%
54	Cecal Neoplasms	16.2%
55	Duodenal Neoplasms	16.2%
56	Mesenteric vascular insufficiency	15.5%
57	Esophageal Neoplasms	15.5%
58	Colonic Pseudo-Obstruction	15.3%
59	Esophageal Atresia	15.3%
60	Intestinal Atresia	15.3%
61	Mesenteric Vascular Occlusion	15.3%
62	Intestinal Fistula	15.1%
63	Enterocutaneous Fistula	15.1%
64	Colonic Diseases, Functional	14.8%
65	Esophageal motility disorders	14.8%
66	Fecal Incontinence	14.8%
67	Fecal Impaction	14.8%
68	Intussusception	14.8%
69	Mallory-Weiss Syndrome	14.8%
70	Megacolon	14.8%
71	Ileus	14.8%
72	Meconium ileus	14.8%
73	Enterocolitis, Pseudomembranous	14.6%
74	pseudomembranous colitis	14.6%
75	Dysentery, Bacillary	14.6%
76	Rectal Fistula	14.3%
77	Anal Fistula	14.3%
78	Esophageal Perforation	14.3%
79	Intestinal Diseases, Parasitic	14.3%
80	Colitis, Ischemic	13.7%
81	Barrett Esophagus	13.6%
82	Deglutition Disorders	13.6%
83	Anus Neoplasms	13.6%
84	Sigmoid Neoplasms	13.6%
85	Appendiceal Neoplasms	13.3%
86	Colonic Neoplasms	13.3%
87	Rectal Neoplasms	13.3%
88	Gastrointestinal Stromal Tumors	13.2%
89	Peptic Ulcer Hemorrhage	13.2%
90	Digestive System Neoplasms	12.2%
91	Esophageal Achalasia	12.2%
92	Anal Fissure	12.2%
93	Intestinal Pseudo-Obstruction	12.2%
94	Irritable Bowel Syndrome	12.2%
95	Superior Mesenteric Artery Syndrome	12.2%
96	Neurogenic Bowel	12.2%
97	Anal Ulcer	12.2%
98	Adenomatous Polyposis Coli	11%
99	Bile Duct Diseases	10.3%
100	Cholelithiasis	10.3%
101	Chylous Ascites	10.3%
102	Fatty Liver	10.3%
103	Hepatitis	10.3%
104	Portal Hypertension	10.3%
105	Liver Cirrhosis	10.3%
106	Liver neoplasms	10.3%
107	Pancreatic Insufficiency	10.3%
108	Pancreatitis	10.3%
109	Pneumoperitoneum	10.3%
110	Focal Nodular Hyperplasia	10.3%
111	Hepatic Insufficiency	10.3%
112	Steatohepatitis	10.3%
113	Pancreatic Fistula	10.3%
114	Hemorrhoids	10.1%
115	Melena	10.1%
116	Afferent Loop Syndrome	9.9%
117	Celiac Disease	9.9%
118	Short Bowel Syndrome	9.9%
119	Sprue, Tropical	9.9%
120	Steatorrhea	9.9%
121	Rectocele	9.9%
122	Sprue	9.9%
123	Hematemesis	9.8%
124	Diverticulitis	9.8%
125	Rectal Prolapse	9.8%
126	Cholecystolithiasis	8.9%
127	Biliary cirrhosis	8.6%
128	Peritoneal Neoplasms	8.2%
129	Pruritus Ani	8.2%
130	Bile Duct Neoplasms	7.9%
131	gallbladder neoplasm	7.9%
132	Giardiasis	7.7%
133	Choledocholithiasis	7.7%
134	Laryngopharyngeal Reflux	7.5%
135	Diverticulum	7.5%
136	Diverticulosis	7.5%
137	Liver Diseases, Parasitic	7.3%
138	Hepatic Veno-Occlusive Disease	7%
139	Pancreatic Cyst	7%
140	Peliosis Hepatis	7%
141	Hepatopulmonary Syndrome	7%
142	Pancreatic Neoplasm	6.9%
143	Choledochal Cyst	6.8%
144	Anus, Imperforate	6.8%
145	Hemoperitoneum	6.8%
146	Hepatomegaly	6.8%
147	Mesenteric Panniculitis	6.8%
148	Panniculitis, Peritoneal	6.8%
149	Peritonitis	6.8%
150	Peritoneal Fibrosis	6.8%
151	Encapsulating Peritoneal Sclerosis	6.8%
152	Anorectal Malformations	6.8%
153	Biliary Fistula	6.7%
154	Gastric Fistula	6.7%
155	Hepatic Vein Thrombosis	6.7%
156	Liver Abscess	6.7%
157	Budd-Chiari Syndrome	6.7%
158	Cholangitis	6.7%
159	Cholecystitis	6.7%
160	Cholestasis	6.7%
161	Common Bile Duct Diseases	6.7%
162	Hepatitis, Chronic	6.7%
163	Liver Failure	6.7%
164	Pancreatitis, Chronic	6.7%
165	Non-alcoholic Fatty Liver Disease	6.7%
166	Chronic active hepatitis	6.7%
167	Fatty Liver, Alcoholic	6.6%
168	Hepatitis, Alcoholic	6.6%
169	Liver Cirrhosis, Alcoholic	6.6%
170	Peutz-Jeghers Syndrome	6%
171	Lactose Intolerance	5.9%
172	Hepatocellular Adenoma	5.3%
173	Chemical and Drug Induced Liver Injury	5.3%
174	Hepatorenal Syndrome	5%
175	Cholestasis, Extrahepatic	4.9%
176	Biliary Dyskinesia	4.9%
177	Cholangitis, Sclerosing	4.9%
178	Liver Failure, Acute	4.9%
179	Acalculous Cholecystitis	4.9%
180	End Stage Liver Disease	4.9%
181	Hepatitis, Animal	4.8%
182	Hepatitis, Viral, Human	4.8%
183	Liver Abscess, Amebic	4.5%
184	Liver Cirrhosis, Experimental	4.4%
185	Liver Neoplasms, Experimental	4.4%
186	Pancreatic Pseudocyst	4.4%
187	Pancreatitis, Alcoholic	4.4%
188	Cryptosporidiosis	4.3%
189	Cystic Fibrosis	4.2%
190	Massive Hepatic Necrosis	4.1%
191	Emphysematous Cholecystitis	4.1%
192	Sphincter of Oddi Dysfunction	4.1%
193	Porphyrias, Hepatic	4.1%
194	Congenital Hyperinsulinism	4.1%
195	Hepatitis B, Chronic	3.6%
196	Hepatitis C, Chronic	3.6%
197	CREST Syndrome	3.5%
198	Fascioliasis	3.4%
199	Autoimmune hepatitis	3.4%
200	Echinococcosis, Hepatic	3.4%
201	Chemical and Drug Induced Liver Injury, Chronic	3.3%
202	Reye Syndrome	3.3%
203	Carcinoma, Pancreatic Ductal	3.3%
204	insulinoma	2.8%
205	Gastrinoma	2.8%
206	Glucagonoma	2.8%
207	Hepatitis, Viral, Animal	2.7%
208	Nesidioblastosis	2.6%
209	Variegate Porphyria	2.6%
210	Acute intermittent porphyria	2.6%
211	Porphyria Cutanea Tarda	2.6%
212	Hepatitis E	2.6%
213	Hepatitis B	2.5%
214	Hepatitis C	2.5%
215	Hepatitis A	2.5%
216	Hepatic Encephalopathy	2.5%
217	Vipoma	2.4%
218	Zellweger Syndrome	1.8%
219	Hepatolenticular Degeneration	1.6%
220	Rift Valley Fever	1.2%

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