MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Potassium Deficiency

(UMLS:C0032827)

Definition:: A condition due to decreased dietary intake of potassium, as in starvation or failure to administer in intravenous solutions, or to gastrointestinal loss in diarrhea, chronic laxative abuse, vomiting, gastric suction, or bowel diversion. Severe potassium deficiency may produce muscular weakness and lead to paralysis and respiratory failure. Muscular malfunction may result in hypoventilation, paralytic ileus, hypotension, muscle twitches, tetany, and rhabomyolysis. Nephropathy from potassium deficit impairs the concentrating mechanism, producing POLYURIA and decreased maximal urinary concentrating ability with secondary POLYDIPSIA. (Merck Manual, 16th ed)
UMLS ID:: C0032827
MeSH ID:: D011191

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.654.521.500.617

Synonym(s)

Potassium Deficiency

K deficiency

POTASSIUM DEFICIENCY

Potassium deficiency

deficiency k

deficiency potassium

deficiency; potassium

k deficiency

potassium deficiencies

10.

potassium deficiency

11.

potassium; deficiency

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Fructose	17855639	CTD
2	Hydrochlorothiazide	2454086	CTD
3	Prednisone		SIDER
4	Triamcinolone		SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Magnesium Deficiency	48.4%
2	Protein Deficiency	48.4%
3	Avitaminosis	48.4%
4	Ascorbic Acid Deficiency	36%
5	Vitamin A Deficiency	36%
6	Vitamin D Deficiency	36%
7	Vitamin E Deficiency	36%
8	Marasmus	36%
9	Starvation	34.4%
10	Refeeding Syndrome	34.4%
11	Folic Acid Deficiency	29.9%
12	Pellagra	29.9%
13	Thiamine Deficiency	29.9%
14	Vitamin B 12 Deficiency	29.9%
15	Vitamin B 6 Deficiency	29.9%
16	Pyridoxine Deficiency	29.9%
17	Beriberi	26.8%
18	Child Nutrition Disorders	25.4%
19	Hypervitaminosis A	25.4%
20	Infant Nutrition Disorders	25.4%
21	Wasting Syndrome	23%
22	Kwashiorkor	22.6%
23	Vitamin K Deficiency	18.4%
24	Anemia, Pernicious	17.9%
25	Metabolic Diseases	16.4%
26	Rickets	16.2%
27	Hyperhomocysteinemia	15.3%
28	Scurvy	15.2%
29	Osteomalacia	13.4%
30	Wernicke Encephalopathy	10.8%
31	Subacute Combined Degeneration	9.4%
32	Acid-Base Imbalance	8.5%
33	Calcium Metabolism Disorders	8.5%
34	Iron Metabolism Disorders	8.5%
35	Phosphorus Metabolism Disorders	8.5%
36	Water-Electrolyte Imbalance	8.5%
37	Lipid Metabolism Disorders	8.5%
38	Mitochondrial Diseases	8.5%
39	Glucose Metabolism Disorders	8.5%
40	Renal Osteodystrophy	8.4%
41	Renal rickets	8.4%
42	Hypercalcemia	6.6%
43	Hypocalcemia	6.6%
44	Milk-Alkali Syndrome	6.6%
45	HIV Wasting Syndrome	6.5%
46	Familial Hypophosphatemic Rickets	6.1%
47	Obesity	5.8%
48	Osteopenia	5.7%
49	Brain Diseases, Metabolic	5.6%
50	Lipodystrophy	5%
51	Acidosis	4.9%
52	Alkalosis	4.9%
53	Amyloidosis	4.9%
54	Calcinosis	4.9%
55	Hyperglycemia	4.9%
56	Hyperinsulinism	4.9%
57	Hyperkalemia	4.9%
58	Hypernatremia	4.9%
59	Hypoglycemia	4.9%
60	Hypokalemia	4.9%
61	Hyponatremia	4.9%
62	Xanthomatosis	4.9%
63	Hypophosphatemia	4.9%
64	Metabolic acidosis	4.9%
65	Dyslipidemias	4.9%
66	Iron Overload	4.9%
67	Xanthoma	4.9%
68	Obesity, Abdominal	4.8%
69	Pseudohypoparathyroidism	4.4%
70	Brain Diseases, Metabolic, Inborn	3.9%
71	Pediatric Obesity	3.8%
72	Diabetes Mellitus	3.5%
73	Leigh Disease	3.4%
74	Dehydration	3.4%
75	Lipomatosis	3.4%
76	Water Intoxication	3.4%
77	Werner Syndrome	3.4%
78	Achlorhydria	3.3%
79	Amino Acid Metabolism, Inborn Errors	3.3%
80	Bloom Syndrome	3.3%
81	Carbohydrate Metabolism, Inborn Errors	3.3%
82	Metal Metabolism, Inborn Errors	3.3%
83	Osteoporosis	3.3%
84	Progeria	3.3%
85	Lysosomal Storage Diseases	3.3%
86	Bone Demineralization, Pathologic	3.3%
87	Cytochrome-c Oxidase Deficiency	3.3%
88	Peroxisomal Disorders	3.3%
89	Post-Traumatic Osteoporosis	3.3%
90	Prader-Willi Syndrome	3.3%
91	Celiac Disease	3.3%
92	Sprue, Tropical	3.3%
93	Steatorrhea	3.3%
94	Sprue	3.3%
95	Lactose Intolerance	3.2%
96	Acidosis, Lactic	3.2%
97	Calciphylaxis	3.2%
98	Hemosiderosis	3.2%
99	Hypolipoproteinemias	3.2%
100	Ketosis	3.2%
101	Ketonuria	3.2%
102	Ketoacidosis	3.2%
103	Ketonemia	3.2%
104	Vascular calcification	3.2%
105	Carbamoyl-Phosphate Synthase I Deficiency Disease	3%
106	Hyperlipoproteinemia Type IV	2.9%
107	Hyperlipoproteinemia Type V	2.9%
108	Diabetic Ketoacidosis	2.8%
109	Hyperlipidemia, Familial Combined	2.8%
110	Smith-Lemli-Opitz Syndrome	2.8%
111	Galactosemias	2.8%
112	Urea Cycle Disorders, Inborn	2.8%
113	Tyrosinemias	2.8%
114	Mitochondrial Encephalomyopathies	2.7%
115	Congenital Hyperinsulinism	2.7%
116	Hyperlipoproteinemia Type III	2.6%
117	Mitochondrial Myopathies	2.5%
118	Myelinolysis, Central Pontine	2.5%
119	Glycosuria	2.5%
120	Reye Syndrome	2.5%
121	Hepatic Encephalopathy	2.4%
122	Hyperphosphaturia	2.4%
123	Hypercholesterolemia	2.4%
124	Hyperlipoproteinemias	2.4%
125	Hypertriglyceridemia	2.4%
126	Hypoalphalipoproteinemias	2.4%
127	Homocystinuria	2.2%
128	Acidosis, Respiratory	2.2%
129	Adiposis Dolorosa	2.2%
130	Alkalosis, Respiratory	2.2%
131	Alkaptonuria	2.2%
132	Glycogen Storage Disease	2.2%
133	Hypophosphatasia	2.2%
134	Insulin Resistance	2.2%
135	Osteoporosis, Postmenopausal	2.2%
136	Propionic acidemia	2.2%
137	Dihydropyrimidine Dehydrogenase Deficiency	2.2%
138	Cystinosis	2.2%
139	Renal tubular acidosis	2.1%
140	Glycogen storage disease type II	2.1%
141	Gaucher Disease	2.1%
142	Amyloid Neuropathies, Familial	2%
143	Porphyrias, Hepatic	2%
144	Necrobiosis Lipoidica Diabeticorum	2%
145	Fanconi Anemia	1.9%
146	Nesidioblastosis	1.9%
147	Neuronal Ceroid-Lipofuscinoses	1.9%
148	HIV-Associated Lipodystrophy Syndrome	1.8%
149	Zellweger Syndrome	1.8%
150	MELAS Syndrome	1.8%
151	Menkes Kinky Hair Syndrome	1.8%
152	Adrenoleukodystrophy	1.7%
153	Gestational Diabetes	1.7%
154	Latent Autoimmune Diabetes in Adults	1.7%
155	Tay-Sachs Disease	1.7%
156	Diabetes Mellitus, Experimental	1.7%
157	Niemann-Pick Disease, Type C	1.6%
158	Hepatolenticular Degeneration	1.6%
159	Nephrocalcinosis	1.6%
160	Tetany	1.6%
161	Friedreich Ataxia	1.6%
162	Refsum Disease	1.6%
163	Glycosuria, Renal	1.6%
164	Cerebral Amyloid Angiopathy	1.6%
165	Glycogen Storage Disease Type I	1.6%
166	Glycogen Storage Disease Type V	1.6%
167	Mucopolysaccharidosis III	1.6%
168	Fabry Disease	1.6%
169	Kernicterus	1.4%
170	Cockayne Syndrome	1.4%
171	Familial Periodic Paralysis	1.3%
172	Primary amyloidosis	1.3%
173	Kearns-Sayre syndrome	1.3%
174	Variegate Porphyria	1.3%
175	Acute intermittent porphyria	1.3%
176	Porphyria Cutanea Tarda	1.3%
177	Renal Aminoacidurias	1.3%
178	Fanconi Syndrome	1.3%
179	Pseudohypoaldosteronism	1.3%
180	Liddle Syndrome	1.3%
181	Ataxia Telangiectasia	1.3%
182	Optic Atrophy, Hereditary, Leber	1.2%
183	Sjogren-Larsson Syndrome	1.1%
184	Xeroderma Pigmentosum	1.1%
185	Gout	1.1%
186	Amyotrophic Lateral Sclerosis	1.1%
187	Antley-Bixler Syndrome Phenotype	1.1%
188	Canavan Disease	1.1%
189	Alexander Disease	1.1%
190	Mucopolysaccharidosis II	1.1%
191	Hypokalemic periodic paralysis	1%
192	Frontotemporal dementia	1%
193	Cystinuria	1%
194	CREST Syndrome	0.9%
195	Albinism	0.8%
196	Arthritis, Gouty	0.8%
197	Ichthyosis, X-Linked	0.7%

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