MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Cystinuria

(UMLS:C0010691)

Definition:: An inherited disorder due to defective reabsorption of CYSTINE and other BASIC AMINO ACIDS by the PROXIMAL RENAL TUBULES. This form of aminoaciduria is characterized by the abnormally high urinary levels of cystine; LYSINE; ARGININE; and ORNITHINE. Mutations involve the amino acid transport protein gene SLC3A1.
UMLS ID:: C0010691
MeSH ID:: D003555

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.419.815.885.250

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.419.815.885.250

Classification 3:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.320.565.861.885.250

Classification 4:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.452.648.861.885.250

Synonym(s)

Cystinuria

CSNU - Cystinuria

CYSTINURIA

Cystinuria, NOS

High urine cystine levels

cystinuria

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Valproic Acid	FAERS: 2		US FAERS
2	Liraglutide	FAERS: 1		US FAERS
3	N-acetylpenicillamine		5706615	CTD
4	Penicillamine		View details 3752071 4048879 4169108 5641080 5694119 5953529 6027079 7342491 7370063 22843330	CTD
5	Tiopronin		808002 6811078	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Fanconi Syndrome	36.2%
2	Pseudohypoaldosteronism	36.2%
3	Liddle Syndrome	36.2%
4	Hyperphosphaturia	33.8%
5	Renal tubular acidosis	33.8%
6	Glycosuria, Renal	30.5%
7	Anuria	21.1%
8	Nephrolithiasis	21.1%
9	Zellweger Syndrome	19.7%
10	Hydronephrosis	19.4%
11	Hyperoxaluria	19.4%
12	Kidney Cortex Necrosis	19.4%
13	Kidney Papillary Necrosis	19.4%
14	Nephritis	19.4%
15	Nephrosclerosis	19.4%
16	Nephrosis	19.4%
17	Perinephritis	19.4%
18	Kidney Failure	19.4%
19	Uremia	19.4%
20	Oxalosis	19.4%
21	Renal Insufficiency	19.4%
22	Amino Acid Metabolism, Inborn Errors	18.8%
23	Carbohydrate Metabolism, Inborn Errors	18.8%
24	Metal Metabolism, Inborn Errors	18.8%
25	Progeria	18.8%
26	Lysosomal Storage Diseases	18.8%
27	Peroxisomal Disorders	18.8%
28	Nephrocalcinosis	18.7%
29	Familial Hypophosphatemic Rickets	17.2%
30	Brain Diseases, Metabolic, Inborn	17.2%
31	Tuberculosis, Renal	17.1%
32	Diabetes Insipidus	16.8%
33	Hepatorenal Syndrome	16.8%
34	Diabetic Nephropathy	16.7%
35	Renal hypertension	16.7%
36	Renal Artery Obstruction	16.7%
37	Renal Artery Stenosis	16.7%
38	Urinary Bladder Diseases	15.9%
39	Ureteral Diseases	15.9%
40	Urethral Diseases	15.9%
41	Urination Disorders	15.9%
42	Urolithiasis	15.9%
43	Smith-Lemli-Opitz Syndrome	15.7%
44	Kidney Neoplasm	15.2%
45	Galactosemias	14.9%
46	Urea Cycle Disorders, Inborn	14.9%
47	Tyrosinemias	14.9%
48	Urinary tract infection	13.8%
49	Leigh Disease	13.7%
50	Cytochrome-c Oxidase Deficiency	13.4%
51	Renal Osteodystrophy	13.4%
52	Renal rickets	13.4%
53	Ureterolithiasis	13.1%
54	AIDS-Associated Nephropathy	13%
55	Pseudohypoparathyroidism	12.9%
56	Multicystic Dysplastic Kidney	12.8%
57	Polycystic Kidney Diseases	12.8%
58	Menkes Kinky Hair Syndrome	12.7%
59	Urogenital Abnormalities	12.5%
60	Kidney Calculi	12%
61	Glycogen storage disease type II	11.9%
62	Hyperhomocysteinemia	11.7%
63	Hepatolenticular Degeneration	11.7%
64	Hypolipoproteinemias	11.6%
65	Adrenoleukodystrophy	11.6%
66	Homocystinuria	11.6%
67	Glomerulonephritis	11.5%
68	Nephritis, Interstitial	11.5%
69	Lipoid nephrosis	11.5%
70	Nephrotic Syndrome	11.5%
71	Pyelitis	11.5%
72	Pyonephrosis	11.5%
73	Nephrogenic Diabetes Insipidus	11.5%
74	Congenital Nephrogenic Diabetes Insipidus	11.5%
75	Acute kidney injury	11.5%
76	Pyelonephritis	11.5%
77	Lactose Intolerance	11.4%
78	Werner Syndrome	11.4%
79	Refsum Disease	11.2%
80	Alkaptonuria	11.2%
81	Glycogen Storage Disease	11.2%
82	Hypophosphatasia	11.2%
83	Propionic acidemia	11.2%
84	Dihydropyrimidine Dehydrogenase Deficiency	11.2%
85	Cystinosis	11.2%
86	Carbamoyl-Phosphate Synthase I Deficiency Disease	11.1%
87	Glycosuria	10.9%
88	Hyperlipidemia, Familial Combined	10.9%
89	Bladder Exstrophy	10.9%
90	Epispadias	10.9%
91	Albinism	10.7%
92	Hyperlipoproteinemia Type III	10.6%
93	Bladder neck obstruction	10.4%
94	Hyperlipoproteinemia Type IV	10.1%
95	Hyperlipoproteinemia Type V	10.1%
96	Amyloid Neuropathies, Familial	10.1%
97	Azotemia	10%
98	Ichthyosis, X-Linked	10%
99	Hypertension, Renovascular	9.9%
100	Mucopolysaccharidosis III	9.9%
101	Wasting Syndrome	9.9%
102	Mucopolysaccharidosis II	9.8%
103	Pyelocystitis	9.6%
104	Neuronal Ceroid-Lipofuscinoses	9.3%
105	Gaucher Disease	8.9%
106	Nephroblastoma	8.9%
107	Fabry Disease	8.8%
108	Acid-Base Imbalance	8.8%
109	Calcium Metabolism Disorders	8.8%
110	Iron Metabolism Disorders	8.8%
111	Phosphorus Metabolism Disorders	8.8%
112	Water-Electrolyte Imbalance	8.8%
113	Lipid Metabolism Disorders	8.8%
114	Mitochondrial Diseases	8.8%
115	Glucose Metabolism Disorders	8.8%
116	Cystitis	8.7%
117	Ureteral obstruction	8.7%
118	Ureterocele	8.7%
119	Urethral Obstruction	8.7%
120	Urethritis	8.7%
121	Vesico-Ureteral Reflux	8.7%
122	Urinary Retention	8.7%
123	Hemolytic-Uremic Syndrome	8.7%
124	Familial Periodic Paralysis	8.5%
125	Ureteral Calculi	8.5%
126	Mesoblastic Nephroma	8.2%
127	Polycystic Kidney, Autosomal Dominant	8.2%
128	Cockayne Syndrome	8.1%
129	Renal Cell Carcinoma	8.1%
130	Papillary Renal Cell Carcinoma	8.1%
131	Urinary Bladder Fistula	8.1%
132	Bladder Neoplasm	8.1%
133	Ureteral Neoplasms	8.1%
134	Urethral Neoplasms	8.1%
135	Hypercalcemia	8.1%
136	Hypocalcemia	8.1%
137	Milk-Alkali Syndrome	8.1%
138	Antley-Bixler Syndrome Phenotype	8%
139	Hypoalphalipoproteinemias	7.7%
140	Balkan Nephropathy	7.7%
141	Focal glomerulosclerosis	7.7%
142	Kidney Failure, Chronic	7.7%
143	Gout	7.6%
144	Neoplastic Syndromes, Hereditary	7.6%
145	Cystic Fibrosis	7.6%
146	Bacteriuria	7.5%
147	Hematuria	7.5%
148	Oliguria	7.5%
149	Polyuria	7.5%
150	Proteinuria	7.5%
151	Pyuria	7.5%
152	Urinary Calculi	7.5%
153	CHARGE Syndrome	7.5%
154	Cystocele	7.4%
155	Urinary Incontinence	7.4%
156	Sjogren-Larsson Syndrome	7.4%
157	Osteopenia	7.4%
158	Glycogen Storage Disease Type I	7.4%
159	Glycogen Storage Disease Type V	7.4%
160	Brain Diseases, Metabolic	7.3%
161	Multiple Epiphyseal Dysplasia	7.3%
162	Osteochondrodysplasias	7.3%
163	Pelger-Huet Anomaly	7.3%
164	Myasthenic Syndromes, Congenital	7.3%
165	Fetal Diseases	7.2%
166	MELAS Syndrome	7%
167	Lipodystrophy	6.9%
168	Aicardi's syndrome	6.9%
169	Niemann-Pick Disease, Type C	6.8%
170	Glomerulonephritis, Membranoproliferative	6.8%
171	Hypospadias	6.7%
172	Enuresis	6.6%
173	Nail-Patella Syndrome	6.6%
174	Tay-Sachs Disease	6.6%
175	Canavan Disease	6.6%
176	Alexander Disease	6.6%
177	Dwarfism	6.5%
178	Horseshoe Kidney	6.4%
179	Rickets	6.4%
180	Ataxia Telangiectasia	6.3%
181	Muscular Dystrophy	6.3%
182	Osteogenesis Imperfecta	6.3%
183	Porphyrias, Hepatic	6.1%
184	Infertility	6.1%
185	Anemia, Sickle Cell	6.1%
186	Thalassemia	6.1%
187	Muscular Dystrophy, Duchenne	6%
188	Fanconi Anemia	6%
189	Kallmann Syndrome	5.9%
190	Anti-Glomerular Basement Membrane Disease	5.9%
191	Lupus Nephritis	5.8%
192	Beckwith-Wiedemann Syndrome	5.8%
193	Wolf-Hirschhorn Syndrome	5.8%
194	Atypical Hemolytic Uremic Syndrome	5.7%
195	Hermaphroditism	5.7%
196	Disorders of Sex Development	5.7%
197	Genital Diseases, Male	5.7%
198	Deformity	5.7%
199	Nutrition Disorders	5.7%
200	Hypokalemic periodic paralysis	5.6%
201	Autoimmune Lymphoproliferative Syndrome	5.6%
202	Congenital Hyperinsulinism	5.5%
203	Pregnancy Complications	5.5%
204	Angioedemas, Hereditary	5.5%
205	Bloom Syndrome	5.4%
206	Fragile X Syndrome	5.3%
207	Marfan Syndrome	5.3%
208	Urologic Neoplasms	5.3%
209	Denys-Drash Syndrome	5.2%
210	Urethral Stenosis	5.2%
211	Urethral stricture	5.2%
212	Smith-Magenis syndrome	5.1%
213	Cri-du-Chat Syndrome	5.1%
214	Down Syndrome	5.1%
215	Trisomy 21	5.1%
216	Prader-Willi Syndrome	5%
217	Arthritis, Gouty	5%
218	Kartagener Syndrome	4.9%
219	Wiskott-Aldrich Syndrome	4.9%
220	Alstrom Syndrome	4.8%
221	Optic Atrophy, Hereditary, Leber	4.8%
222	Xeroderma Pigmentosum	4.8%
223	Acidosis	4.8%
224	Alkalosis	4.8%
225	Amyloidosis	4.8%
226	Calcinosis	4.8%
227	Hyperglycemia	4.8%
228	Hyperinsulinism	4.8%
229	Hyperkalemia	4.8%
230	Hypernatremia	4.8%
231	Hypoglycemia	4.8%
232	Hypokalemia	4.8%
233	Hyponatremia	4.8%
234	Familial Mediterranean Fever	4.8%
235	Xanthomatosis	4.8%
236	Hypophosphatemia	4.8%
237	Metabolic acidosis	4.8%
238	Dyslipidemias	4.8%
239	Iron Overload	4.8%
240	Xanthoma	4.8%
241	Sexually Transmitted Diseases	4.8%
242	Genital Herpes	4.6%
243	Holoprosencephaly	4.6%
244	Ectodermal Dysplasia	4.5%
245	Aplasia Cutis Congenita	4.5%
246	Albuminuria	4.4%
247	Hemoglobinuria	4.4%
248	Urge Incontinence	4.4%
249	Myotonic Dystrophy	4.4%
250	Endometriosis	4.3%
251	Uterine Diseases	4.3%
252	Vaginal Diseases	4.3%
253	Vulvar Diseases	4.3%
254	Endometrioma	4.3%
255	Mitochondrial Encephalomyopathies	4.3%
256	Friedreich Ataxia	4.3%
257	Genital Neoplasms, Male	4.2%
258	Chorioamnionitis	4.2%
259	Meconium Aspiration Syndrome	4.2%
260	Diabetes Mellitus	4.2%
261	Rubinstein-Taybi Syndrome	4.1%
262	Gestational Diabetes	4.1%
263	Rett Syndrome	4.1%
264	Tuberous Sclerosis	4.1%
265	Dehydration	4.1%
266	Lipomatosis	4.1%
267	Water Intoxication	4.1%
268	Achlorhydria	4%
269	Osteoporosis	4%
270	Bone Demineralization, Pathologic	4%
271	Post-Traumatic Osteoporosis	4%
272	Williams Syndrome	4%
273	Celiac Disease	4%
274	Sprue, Tropical	4%
275	Steatorrhea	4%
276	Sprue	4%
277	Diurnal Enuresis	3.9%
278	Cryptorchidism	3.9%
279	Osteomalacia	3.8%
280	Primary Ciliary Dyskinesia	3.8%
281	Retinal Dysplasia	3.7%
282	Aniridia	3.7%
283	Genital Neoplasms, Female	3.6%
284	Epidermolysis Bullosa	3.6%
285	Variegate Porphyria	3.6%
286	Acute intermittent porphyria	3.6%
287	Porphyria Cutanea Tarda	3.6%
288	HIV Wasting Syndrome	3.6%
289	Sickle Cell Trait	3.6%
290	Cutis Laxa	3.5%
291	Mitochondrial Myopathies	3.5%
292	Retinitis Pigmentosa	3.5%
293	Myelinolysis, Central Pontine	3.5%
294	Pigmentary retinopathy	3.5%
295	Porokeratosis	3.5%
296	Keratoderma, Palmoplantar	3.5%
297	Chronic granulomatous disease	3.5%
298	Reye Syndrome	3.5%
299	Vesicovaginal Fistula	3.4%
300	Hepatic Encephalopathy	3.4%
301	Diabetic Ketoacidosis	3.4%
302	Welander Distal Myopathy	3.4%
303	Uterine Neoplasms	3.4%
304	Vaginal Neoplasms	3.4%
305	Vulvar Neoplasms	3.4%
306	Uterine Cancer	3.4%
307	Nesidioblastosis	3.4%
308	Kernicterus	3.3%
309	Uterine Inversion	3.2%
310	Endometritis	3.2%
311	Fetal Growth Retardation	3.2%
312	Fetal Hypoxia	3.1%
313	Fetal Alcohol Spectrum Disorders	3.1%
314	Gonadal Dysgenesis	3.1%
315	Adrenogenital Syndrome	3.1%
316	Ovotesticular Disorders of Sex Development	3.1%
317	Duane Retraction Syndrome	3.1%
318	Peutz-Jeghers Syndrome	3%
319	Myotonia Congenita	3%
320	Penile Neoplasms	3%
321	Prostatic Neoplasms	3%
322	Thrombasthenia	3%
323	Antithrombin III Deficiency	3%
324	Necrobiosis Lipoidica Diabeticorum	3%
325	Protein C Deficiency	3%
326	Afibrinogenemia	3%
327	Dystonia Musculorum Deformans	3%
328	Factor VII Deficiency	3%
329	Factor X Deficiency	3%
330	Factor XII Deficiency	3%
331	Hemophilia A	3%
332	Activated Protein C Resistance	3%
333	Factor II deficiency	3%
334	Factor VIII Deficiency	3%
335	Factor V deficiency	3%
336	Factor XI Deficiency	3%
337	Hypoprothrombinemias	3%
338	Lafora Disease	3%
339	Unverricht-Lundborg Syndrome	3%
340	Anemia, Diamond-Blackfan	3%
341	Pseudoxanthoma Elasticum	3%
342	Acute Chest Syndrome	2.9%
343	Abdominal Cramps	2.9%
344	Abnormalities, Drug-Induced	2.9%
345	Amniotic Band Syndrome	2.9%
346	Asphyxia Neonatorum	2.9%
347	Child Nutrition Disorders	2.9%
348	Epididymitis	2.9%
349	Hypervitaminosis A	2.9%
350	Infant Nutrition Disorders	2.9%
351	Infant, Premature, Diseases	2.9%
352	Penile Diseases	2.9%
353	Prostatic Diseases	2.9%
354	Situs Inversus	2.9%
355	Spermatic Cord Torsion	2.9%
356	Hemospermia	2.9%
357	Malnutrition	2.9%
358	Infantile Colic	2.9%
359	Testicular Hydrocele	2.9%
360	Wernicke Encephalopathy	2.9%
361	Dyspareunia	2.9%
362	HIV-Associated Lipodystrophy Syndrome	2.9%
363	Xeroderma	2.9%
364	Mobius Syndrome	2.9%
365	Acidosis, Lactic	2.9%
366	Calciphylaxis	2.9%
367	Hemosiderosis	2.9%
368	Ketosis	2.9%
369	Ketonuria	2.9%
370	Ketoacidosis	2.9%
371	Ketonemia	2.9%
372	Vascular calcification	2.9%
373	Turner Syndrome	2.8%
374	Uterine Rupture	2.8%
375	Multiple Endocrine Neoplasia	2.8%
376	Polyhydramnios	2.8%
377	Obstetric Labor Complications	2.8%
378	Ectopic Pregnancy	2.8%
379	Pregnancy, Prolonged	2.8%
380	Puerperal Disorders	2.8%
381	Oligohydramnios	2.8%
382	Prenatal Injuries	2.8%
383	Fallopian Tube Neoplasms	2.7%
384	Congenital Hypothyroidism	2.7%
385	Dermatitis, Atopic	2.7%
386	Klinefelter Syndrome	2.5%
387	Hyperandrogenism	2.5%
388	Eye Abnormalities	2.5%
389	Cardiovascular Abnormalities	2.5%
390	Basal Cell Nevus Syndrome	2.5%
391	Skin Abnormalities	2.5%
392	Testicular Diseases	2.5%
393	Varicocele	2.5%
394	Lymphatic Abnormalities	2.5%
395	Congenital Microtia	2.5%
396	Behcet Syndrome	2.4%
397	Anemia, Neonatal	2.4%
398	Persistent Fetal Circulation Syndrome	2.4%
399	Spermatocele	2.4%
400	Congenital diaphragmatic hernia	2.4%
401	Umbilical hernia	2.4%
402	Abruptio Placentae	2.4%
403	Placenta Accreta	2.4%
404	Acidosis, Respiratory	2.4%
405	Adiposis Dolorosa	2.4%
406	Alkalosis, Respiratory	2.4%
407	Kearns-Sayre syndrome	2.4%
408	Insulin Resistance	2.4%
409	Osteoporosis, Postmenopausal	2.4%
410	Endometrial Hyperplasia	2.4%
411	Pyometra	2.4%
412	Vaginitis	2.4%
413	Vulvitis	2.4%
414	Vaginal Discharge	2.4%
415	Vulvodynia	2.4%
416	Pregnancy Complications, Cardiovascular	2.4%
417	Pregnancy Complications, Neoplastic	2.4%
418	Salpingitis	2.4%
419	Vulvovaginitis	2.4%
420	Pregnancy Complications, Hematologic	2.3%
421	Pregnancy Complications, Infectious	2.3%
422	Fetal Death	2.3%
423	Perinatal death	2.3%
424	Morning Sickness	2.3%
425	Hyperkeratosis, Epidermolytic	2.2%
426	Classical Lissencephalies and Subcortical Band Heterotopias	2.2%
427	Huntington Disease	2.2%
428	ovarian neoplasm	2.2%
429	Neonatal Abstinence Syndrome	2.1%
430	Charcot-Marie-Tooth Disease	2.1%
431	Latent Autoimmune Diabetes in Adults	2.1%
432	Diabetes Mellitus, Experimental	2.1%
433	Congenital nystagmus	2.1%
434	Puerperal Infection	2.1%
435	Toxoplasmosis, Congenital	2.1%
436	Postpartum Hemorrhage	2.1%
437	Syphilis, Congenital	2.1%
438	Tetany	2.1%
439	Oophoritis	2.1%
440	Papillon-Lefevre Disease	2.1%
441	Cerebral Amyloid Angiopathy	2%
442	Endometrial Neoplasms	2%
443	Ovarian Diseases	2%
444	Adnexitis	2%
445	Pruritus Vulvae	2%
446	Uterine hemorrhage	2%
447	Vaginal Fistula	2%
448	Pelvic Inflammatory Disease	2%
449	Hydrops Fetalis	2%
450	Uterine Prolapse	2%
451	Vaginal Prolapse	2%
452	Hypercholesterolemia	1.9%
453	Hyperlipoproteinemias	1.9%
454	Hypertriglyceridemia	1.9%
455	Uterine Cervical Incompetence	1.9%
456	Adenomatous Polyposis Coli	1.9%
457	Anencephaly	1.8%
458	Primary amyloidosis	1.8%
459	Prostatic Neoplasms, Castration-Resistant	1.8%
460	Carcinoma, Endometrioid	1.7%
461	Testicular Neoplasms	1.6%
462	Maxillofacial Abnormalities	1.6%
463	Dural Arteriovenous Fistula	1.6%
464	Abnormalities, Radiation-Induced	1.6%
465	Amyotrophic Lateral Sclerosis	1.6%
466	Dextrocardia	1.6%
467	Multiple Endocrine Neoplasia Type 1	1.6%
468	Balanitis	1.6%
469	Benign prostatic hypertrophy	1.6%
470	Deficiency Diseases	1.6%
471	Phimosis	1.6%
472	Priapism	1.6%
473	prostatitis	1.6%
474	Prune Belly Syndrome	1.6%
475	Starvation	1.6%
476	Twins, Conjoined	1.6%
477	Prostatic Adenoma	1.6%
478	Refeeding Syndrome	1.6%
479	Benign Prostatic Hyperplasia	1.6%
480	Prostatic Hypertrophy	1.6%
481	Prostatic Hyperplasia	1.6%
482	Waardenburg Syndrome	1.6%
483	Ophthalmia Neonatorum	1.5%
484	CREST Syndrome	1.4%
485	Abortion, Habitual	1.4%
486	Dystocia	1.4%
487	Eclampsia	1.4%
488	Fetal Membranes, Premature Rupture	1.4%
489	Placental Insufficiency	1.4%
490	Pre-Eclampsia	1.4%
491	Prenatal Exposure Delayed Effects	1.4%
492	HELLP Syndrome	1.4%
493	Placenta, Retained	1.4%
494	Uterine Cervicitis	1.4%
495	Leukorrhea	1.4%
496	Parametritis	1.4%
497	Candidiasis, Vulvovaginal	1.4%
498	Anophthalmos	1.4%
499	Anus, Imperforate	1.4%
500	Hydranencephaly	1.4%
501	Microphthalmos	1.4%
502	Neural Tube Defects	1.4%
503	Paralysis, Obstetric	1.4%
504	Premature Ejaculation	1.4%
505	Retinopathy of Prematurity	1.4%
506	Tethered Cord Syndrome	1.4%
507	Iniencephaly	1.4%
508	Craniorachischisis	1.4%
509	Limb Deformities, Congenital	1.4%
510	Erectile dysfunction	1.4%
511	Exencephaly	1.4%
512	Septo-Optic Dysplasia	1.4%
513	Craniofacial Abnormalities	1.4%
514	Cortical Dysplasia	1.4%
515	Malformations of Cortical Development	1.4%
516	Anorectal Malformations	1.4%
517	Orchitis	1.3%
518	Chlamydia Infections	1.3%
519	Gonorrhea	1.3%
520	Bronchopulmonary Dysplasia	1.3%
521	Scimitar Syndrome	1.3%
522	Abortion, Veterinary	1.2%
523	Pregnancy Complications, Parasitic	1.2%
524	Bacterial Vaginosis	1.2%
525	Lactation Disorder	1.2%
526	Mastitis	1.2%
527	Depression, Postpartum	1.2%
528	Embryo Loss	1.2%
529	Syphilis	1.2%
530	Fetal Resorption	1.2%
531	granulosa cell tumor	1.2%
532	Carcinoma, Ovarian Epithelial	1.2%
533	Hyperemesis Gravidarum	1.2%
534	Trichomonas Vaginitis	1.2%
535	Uterine Perforation	1.2%
536	Ovarian Hyperstimulation Syndrome	1.2%
537	Frontotemporal dementia	1.2%
538	Metrorrhagia	1.2%
539	Blepharophimosis	1.2%
540	Laryngostenosis	1.2%
541	Mouth Abnormalities	1.2%
542	Respiratory Distress Syndrome, Newborn	1.2%
543	Esophageal Atresia	1.2%
544	Intestinal Atresia	1.2%
545	Pectus excavatum	1.2%
546	Klippel-Feil Syndrome	1.2%
547	Gastroschisis	1.2%
548	Synostosis	1.2%
549	Acrodermatitis	1.2%
550	Lymphangiectasis, Intestinal	1.2%
551	Gianotti-Crosti Syndrome	1.2%
552	Craniosynostosis	1.1%
553	Syndactyly	1.1%
554	Brachycephaly	1.1%
555	Trophoblastic Neoplasms	1.1%
556	Embolism, Amniotic Fluid	1%
557	Corpus Luteum Cyst	1%
558	Ovarian Cysts	1%
559	Arthrogryposis	1%
560	Choanal Atresia	1%
561	Tracheobronchomegaly	1%
562	Laryngocele	1%
563	Breech Presentation	1%
564	Choledochal Cyst	1%
565	Anovulation	1%
566	Menorrhagia	1%
567	Stillbirth	1%
568	Premature Menopause	1%
569	Central Nervous System Cysts	1%
570	Dandy-Walker Syndrome	1%
571	Leukomalacia, Periventricular	1%
572	POEMS Syndrome	1%
573	Microcephaly	1%
574	Macrocephaly	1%
575	Obesity	1%
576	Noonan Syndrome	1%
577	Azoospermia	1%
578	Kwashiorkor	1%
579	Magnesium Deficiency	1%
580	Oligospermia	1%
581	Potassium Deficiency	1%
582	Protein Deficiency	1%
583	Impotence, Vasculogenic	1%
584	Avitaminosis	1%
585	Asthenozoospermia	1%
586	Teratozoospermia	1%
587	Aspermia	1%
588	Laryngomalacia	0.9%
589	Pectus carinatum	0.9%
590	Acrocephalosyndactylia	0.9%
591	Endometrial Stromal Sarcoma	0.9%
592	Lymphogranuloma Venereum	0.9%
593	Jaw Abnormalities	0.8%
594	Cleft Palate	0.8%
595	Amelia	0.8%
596	Arachnodactyly	0.8%
597	Ectopia Cordis	0.8%
598	Ectromelia	0.8%
599	Hemimelia	0.8%
600	Meningomyelocele	0.8%
601	Phocomelia	0.8%
602	Sirenomelia	0.8%
603	Spina Bifida	0.8%
604	Polydactyly	0.8%
605	Brachydactyly	0.8%
606	Plagiocephaly	0.8%
607	Lower Extremity Deformities, Congenital	0.8%
608	Upper Extremity Deformities, Congenital	0.8%
609	Single umbilical artery	0.8%
610	Porencephaly	0.8%
611	Premature Birth	0.8%
612	Poland Syndrome	0.7%
613	Aortic coarctation	0.7%
614	Cor Triatriatum	0.7%
615	Coronary Vessel Anomalies	0.7%
616	Dental Enamel Hypoplasia	0.7%
617	Patent ductus arteriosus	0.7%
618	Ebstein Anomaly	0.7%
619	Heart Septal Defects	0.7%
620	Hyaline Membrane Disease	0.7%
621	Hypodontia	0.7%
622	Macrostomia	0.7%
623	Meningocele	0.7%
624	Microstomia	0.7%
625	Tetralogy of Fallot	0.7%
626	Transposition of Great Vessels	0.7%
627	Hypoplastic Left Heart Syndrome	0.7%
628	May-Thurner Syndrome	0.7%
629	Encephalocele	0.7%
630	Craniofacial Dysostosis	0.7%
631	Polycystic Ovary Syndrome	0.7%
632	Wolff-Parkinson-White Syndrome	0.7%
633	Obesity, Abdominal	0.7%
634	Galactorrhea	0.7%
635	Ascorbic Acid Deficiency	0.6%
636	Vitamin A Deficiency	0.6%
637	Vitamin D Deficiency	0.6%
638	Vitamin E Deficiency	0.6%
639	Marasmus	0.6%
640	Long QT Syndrome	0.6%
641	Platybasia	0.6%
642	Tricuspid Atresia	0.6%
643	Arrhythmogenic Right Ventricular Dysplasia	0.6%
644	Bronchomalacia	0.6%
645	Tracheomalacia	0.6%
646	Pediatric Obesity	0.6%
647	Leydig Cell Tumor	0.6%
648	Micrognathism	0.6%
649	Pierre Robin Syndrome	0.6%
650	Dermal Sinus	0.5%
651	Spina Bifida Cystica	0.5%
652	Spina Bifida Occulta	0.5%
653	Lissencephaly	0.5%
654	Polymicrogyria	0.5%
655	Pachygyria	0.5%
656	Schizencephaly	0.5%
657	Periventricular Nodular Heterotopia	0.5%
658	Retrognathia	0.5%
659	Choriocarcinoma	0.5%
660	Folic Acid Deficiency	0.5%
661	Pellagra	0.5%
662	Thiamine Deficiency	0.5%
663	Vitamin B 12 Deficiency	0.5%
664	Vitamin B 6 Deficiency	0.5%
665	Pyridoxine Deficiency	0.5%
666	Prognathism	0.5%
667	Vitamin K Deficiency	0.5%
668	Aortopulmonary Septal Defect	0.5%
669	Double Outlet Right Ventricle	0.5%
670	Endocardial Cushion Defects	0.5%
671	Myocardial bridging	0.5%
672	Aorticopulmonary Septal Defect	0.5%
673	Mandibulofacial Dysostosis	0.4%
674	Romano-Ward Syndrome	0.4%
675	Beriberi	0.4%
676	Scurvy	0.3%
677	Hydatidiform Mole	0.3%
678	Truncus Arteriosus, Persistent	0.3%
679	Goldenhar Syndrome	0.3%
680	Anemia, Pernicious	0.3%
681	Arteriovenous fistula	0.3%
682	Talipes	0.3%
683	Congenital clubfoot	0.2%
684	Vertical Talus	0.2%
685	Subacute Combined Degeneration	0.2%

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