MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leukomalacia, Periventricular

(UMLS:C0023529)

Definition:: Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)
UMLS ID:: C0023529
MeSH ID:: D007969

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.300.700|C10.228.140.461.550

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.253.612

Classification 3:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.614.521.450

Synonym(s)

Leukomalacia, Periventricular

PVL

PVL - Periventricular leucomalacia

PVL - Periventricular leukomalacia

Periventricular Leukomalacia

Periventricular leucoencephalopathy

Periventricular leucomalacia

Periventricular leukoencephalopathy

Periventricular leukomalacia

10.

White matter necrosis

11.

leukomalacia periventricular

12.

periventricular leucomalacia

13.

periventricular leukomalacia

14.

pvl leukomalacia periventricular

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Betamethasone	12369299	CTD
2	Dexamethasone	2651132 11533345	CTD
3	Indomethacin	2329439 17980183	CTD
4	Magnesium Sulfate	12066082 15496867 16319938	CTD
5	N-(3-(aminomethyl)benzyl)acetamidine	20497644	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Basal Ganglia Cerebrovascular Disease	46.7%
2	Dementia, Vascular	44.9%
3	Brain Infarction	43.7%
4	Vascular Headaches	43.4%
5	Infarction, Middle Cerebral Artery	40.3%
6	Infarction, Anterior Cerebral Artery	40.3%
7	Infarction, Posterior Cerebral Artery	40.3%
8	Moyamoya Disease	40%
9	Carotid Artery Diseases	39.3%
10	Brain Ischemia	39.3%
11	Cerebrovascular accident	39.3%
12	Vasospasm, Intracranial	39.3%
13	Intracranial Arterial Diseases	39.3%
14	Basal Ganglia Hemorrhage	38.6%
15	Hypoxia-Ischemia, Brain	38.1%
16	Intracranial Embolism and Thrombosis	37.9%
17	Carotid Artery Injuries	37.1%
18	Cerebral Infarction	36.2%
19	Brain Stem Infarctions	36.2%
20	Vasculitis, Central Nervous System	34.7%
21	Subarachnoid Hemorrhage, Traumatic	33.7%
22	Carotid Artery Thrombosis	33.4%
23	Putaminal Hemorrhage	33%
24	Lateral Medullary Syndrome	32.5%
25	Meningoencephalitis	31.1%
26	Carotid Stenosis	30.8%
27	Intracranial Aneurysm	30.8%
28	Pituitary Apoplexy	30.7%
29	Carotid Artery, Internal, Dissection	30.2%
30	Subdural Effusion	29.5%
31	Cerebral Arterial Diseases	29.3%
32	Vertebrobasilar Insufficiency	29.3%
33	Basilar Artery Stenosis	29.3%
34	Vertebral Artery Stenosis	29.3%
35	Intracranial Hemorrhage, Hypertensive	29.3%
36	Transient Cerebral Ischemia	29.3%
37	Intracranial Arteriosclerosis	29.2%
38	Cerebral Atherosclerosis	29.2%
39	Cerebral Arteriosclerosis	29.2%
40	Dandy-Walker Syndrome	28.9%
41	Cerebral Thrombosis	28.5%
42	Intracranial Embolism	28.5%
43	Intracranial Thrombosis	28.5%
44	Akinetic Mutism	27.6%
45	Anoxic Encephalopathy	27.6%
46	Basal Ganglia Diseases	27.6%
47	Brain Damage, Chronic	27.6%
48	Cerebellar Diseases	27.6%
49	Encephalitis	27.6%
50	Epilepsy	27.6%
51	Hydrocephalus	27.6%
52	Congenital Hydrocephalus	27.6%
53	Hypothalamic Diseases	27.6%
54	Thalamic Diseases	27.6%
55	Intracranial Hypertension	27.6%
56	Aura	27.6%
57	Leukoencephalopathy	27.6%
58	Neuroaxonal Dystrophies	27.6%
59	Headache Disorders	27.6%
60	Intracranial Hypotension	27.6%
61	Brain Edema	27.6%
62	Brain Hypoxia	27.6%
63	Aqueductal Stenosis	27.6%
64	Encephalomyelitis	26.7%
65	Lupus Vasculitis, Central Nervous System	26.7%
66	Posterior Leukoencephalopathy Syndrome	26.6%
67	Posterior reversible encephalopathy syndrome	26.6%
68	Lewy Body Disease	26%
69	Multiple System Atrophy	25.7%
70	Pneumocephalus	25.5%
71	Parkinsonian Disorders	25.1%
72	Subarachnoid Hemorrhage	25.1%
73	Cerebral Hemorrhage	25.1%
74	Vertebral Artery Dissection	25%
75	Brain Abscess	24.9%
76	Epilepsy, Post-Traumatic	24.4%
77	Subclavian Steal Syndrome	24.3%
78	Sinus Thrombosis, Intracranial	23.8%
79	Brain Hemorrhage, Traumatic	23.8%
80	Brain Diseases, Metabolic	23.3%
81	Dementia	23.3%
82	Giant Cell Arteritis	23.1%
83	Temporal Arteritis	23.1%
84	Myoclonic Epilepsy	22.7%
85	Epilepsy, Temporal Lobe	22.7%
86	Epilepsy, Rolandic	22.7%
87	Benign Rolandic Epilepsy	22.7%
88	Brain Injuries	22.6%
89	Brain Neoplasms	22.5%
90	Huntington Disease	22.4%
91	Meige Syndrome	21.7%
92	Cerebral Ventriculitis	21.7%
93	Cavernous Sinus Thrombosis	21.6%
94	Sagittal Sinus Thrombosis	21.6%
95	Marchiafava-Bignami Disease	21%
96	Cerebellar Neoplasms	21%
97	Brain Death	20.8%
98	Cerebral Amyloid Angiopathy	20.8%
99	Dystonia Musculorum Deformans	20.5%
100	Parkinson Disease	20.2%
101	MELAS Syndrome	20.1%
102	Meningitis	20%
103	Movement Disorders	20%
104	Pachymeningitis	20%
105	Spinal Cord Diseases	20%
106	Spinal Cord Vascular Diseases	20%
107	Shy-Drager Syndrome	20%
108	Ocular Motility Disorders	19.8%
109	Cyclophoria	19.8%
110	Myelitis	19.8%
111	Epidural Abscess	19.7%
112	Amblyopia	19%
113	Juvenile Myoclonic Epilepsy	18.9%
114	Myoclonic Epilepsies, Progressive	18.9%
115	Leukoencephalopathy, Progressive Multifocal	18.8%
116	Creutzfeldt-Jakob disease	18.7%
117	Cerebral Palsy	18.3%
118	Epilepsies, Partial	18.3%
119	Epilepsy, Generalized	18.3%
120	Pseudotumor Cerebri	18.3%
121	Hypertensive Encephalopathy	18.3%
122	Simple Partial Seizures	18.3%
123	Epilepsy, Reflex	18.3%
124	Headache Disorders, Primary	18.3%
125	Headache Disorders, Secondary	18.3%
126	Medication overuse headache	18.3%
127	Hepatolenticular Degeneration	18.1%
128	Neuroleptic Malignant Syndrome	18%
129	Myelinolysis, Central Pontine	18%
130	Progressive supranuclear palsy	17.8%
131	Striatonigral Degeneration	17.5%
132	Central Nervous System Infection	17.2%
133	Pituitary Adenoma	16.9%
134	Pituitary Neoplasms	16.9%
135	Lafora Disease	16.9%
136	Unverricht-Lundborg Syndrome	16.9%
137	Limbic Encephalitis	16.7%
138	Amnesia, Transient Global	16.3%
139	Fabry Disease	16.1%
140	Stiff-Person Syndrome	16%
141	Presenile dementia	16%
142	Senile dementia	16%
143	Hematoma, Subdural	15.8%
144	Hematoma, Epidural, Cranial	15.8%
145	Leukoencephalitis, Acute Hemorrhagic	15.8%
146	Pituitary Diseases	15.8%
147	Retinopathy of Prematurity	15.6%
148	Prion Diseases	15.6%
149	Canavan Disease	15.4%
150	Alexander Disease	15.4%
151	Bronchopulmonary Dysplasia	15.3%
152	Kluver-Bucy Syndrome	15.3%
153	MPTP Poisoning	15%
154	Brain Injuries, Diffuse	14.9%
155	Traumatic Brain Injury	14.9%
156	Cerebellar Ataxia	14.8%
157	Supratentorial Neoplasms	14.8%
158	Ataxia Telangiectasia	14.6%
159	Toxoplasmosis, Cerebral	14.5%
160	Friedreich Ataxia	14.5%
161	Persistent Vegetative State	14.3%
162	Spinal Muscular Atrophy	14.2%
163	Progressive Muscular Atrophy	14.2%
164	Meningitis, Bacterial	14.1%
165	Meningitis, Fungal	14.1%
166	Subacute Combined Degeneration	14.1%
167	Poliomyelitis	14%
168	Hematoma, Subdural, Intracranial	14%
169	Hematoma, Subdural, Chronic	14%
170	Hematoma, Subdural, Acute	14%
171	Paraneoplastic Cerebellar Degeneration	13.9%
172	Encephalomalacia	13.8%
173	Spinal Cord Injuries	13.7%
174	Post-Traumatic Headache	13.7%
175	Tension Headache	13.7%
176	Epilepsy, Complex Partial	13.7%
177	Migraine Disorders	13.7%
178	Abdominal Migraine	13.7%
179	Status Migrainosus	13.7%
180	Cervicogenic Headache	13.7%
181	Ophthalmoplegic Migraine	13.7%
182	Encephalomyelitis, Acute Disseminated	13.5%
183	Myocardial Ischemia	13.5%
184	Respiratory Distress Syndrome, Newborn	13.5%
185	Adrenoleukodystrophy	13.4%
186	Asterixis	13.3%
187	Ballismus	13.3%
188	Kernicterus	13.3%
189	Miller Fisher Syndrome	13.2%
190	Amyotrophic Lateral Sclerosis	13.2%
191	Aortic Aneurysm	13.2%
192	Aortitis	13.2%
193	Leriche Syndrome	13.2%
194	Periphlebitis	13.2%
195	Phlebitis	13.2%
196	Thromboangiitis Obliterans	13.2%
197	Brain Diseases, Metabolic, Inborn	13.2%
198	Reye Syndrome	13.1%
199	Spinal Cord Ischemia	13.1%
200	Hepatic Encephalopathy	13.1%
201	Toxoplasmosis, Congenital	12.7%
202	Cranial nerve diseases	12.3%
203	Demyelinating Diseases	12.3%
204	Demyelination	12.3%
205	Neuromuscular Diseases	12.3%
206	Chronobiology Disorders	12.3%
207	Retinal Vein Occlusion	12.2%
208	Thoracic Outlet Syndrome	12.2%
209	Chronic Fatigue Syndrome	12.1%
210	Abdominal Cramps	12%
211	Amniotic Band Syndrome	12%
212	Aneurysm	12%
213	Angiomatosis	12%
214	Aortic Diseases	12%
215	Arterial Occlusive Diseases	12%
216	Asphyxia Neonatorum	12%
217	Hyperemia	12%
218	Hypotension	12%
219	Superior Vena Cava Syndrome	12%
220	Telangiectasis	12%
221	Vasculitis	12%
222	Venous Insufficiency	12%
223	Peripheral Vascular Diseases	12%
224	Embolism and Thrombosis	12%
225	Angiodysplasia	12%
226	Infantile Colic	12%
227	Capillary Leak Syndrome	12%
228	Prehypertension	12%
229	Arachnoiditis	11.8%
230	Aseptic Meningitis	11.8%
231	Syringomyelia	11.8%
232	Essential Tremor	11.8%
233	Familial Tremor	11.8%
234	Pneumorrhachis	11.8%
235	Writer's Cramp	11.8%
236	Thrombophlebitis	11.8%
237	Hand-Arm Vibration Syndrome	11.8%
238	Myocardial Reperfusion Injury	11.7%
239	Cerebrovascular Disorders	11.7%
240	Mobius Syndrome	11.7%
241	Cerebrovascular Insufficiency	11.7%
242	Mitochondrial Encephalomyopathies	11.6%
243	Empty Sella Syndrome	11.6%
244	Hyperpituitarism	11.6%
245	Hypopituitarism	11.6%
246	Hypophysitis	11.6%
247	Optic Neuropathy, Ischemic	11.5%
248	Anterior Ischemic Optic Neuropathy	11.5%
249	Leukomalacia, Periventricular	11.5%
250	Myelitis, Transverse	11.5%
251	Postphlebitic Syndrome	11.5%
252	Cluster Headache	11.4%
253	Migraine with Aura	11.4%
254	Familial Hemiplegic Migraine	11.4%
255	Chronic Paroxysmal Hemicrania	11.4%
256	SUNCT Syndrome	11.4%
257	Paroxysmal Hemicrania	11.4%
258	Malignant Atrophic Papulosis	11.3%
259	Shwartzman Phenomenon	11.3%
260	Spinal Cord Neoplasms	11.3%
261	Motor Neuron Disease	11.2%
262	Coronary Aneurysm	11.2%
263	Aortic Rupture	11.1%
264	Diffuse Axonal Injury	11.1%
265	Brain Stem Neoplasms	11.1%
266	Tuberculosis, Meningeal	10.8%
267	Subacute Sclerosing Panencephalitis	10.6%
268	Arteriovenous fistula	10.6%
269	Trauma, Nervous System	10.6%
270	Restless Legs Syndrome	10.4%
271	Auditory Perceptual Disorders	10.4%
272	Sturge-Weber Syndrome	10.4%
273	Congenital nystagmus	10.4%
274	Akathisia, Drug-Induced	10.4%
275	Nervous System Neoplasms	10.3%
276	Neurologic Manifestations	10.3%
277	Vascular System Injuries	10.3%
278	Neurotoxicity Syndromes	10.3%
279	Cystic Fibrosis	10.3%
280	Opsoclonus-Myoclonus Syndrome	10.2%
281	Blue Toe Syndrome	10.2%
282	Wernicke Encephalopathy	10.2%
283	AIDS Dementia Complex	10.2%
284	Frontotemporal dementia	10.1%
285	Compartment syndromes	10.1%
286	Hepatic Veno-Occlusive Disease	10.1%
287	Peliosis Hepatis	10.1%
288	Varicocele	10.1%
289	Polyradiculoneuropathy	10%
290	Polyradiculoneuritis	10%
291	Anemia, Neonatal	10%
292	Diabetic Angiopathies	10%
293	Persistent Fetal Circulation Syndrome	10%
294	Reperfusion Injury	10%
295	Splenic Infarction	10%
296	Vascular Neoplasms	10%
297	Central Nervous System Fungal Infections	10%
298	Conus Medullaris Syndrome	10%
299	Vasoplegia	10%
300	Hemorrhoids	9.9%
301	Refsum Disease	9.9%
302	Umbilical hernia	9.9%
303	Hyaline Membrane Disease	9.9%
304	Aortic Aneurysm, Abdominal	9.8%
305	Aortic Aneurysm, Thoracic	9.8%
306	Coronary Thrombosis	9.8%
307	Coronary Artery Disease	9.8%
308	Scimitar Syndrome	9.8%
309	Anterior Spinal Artery Syndrome	9.8%
310	Brain Contusion	9.7%
311	Hyperprolactinemia	9.5%
312	Pick Disease of the Brain	9.4%
313	Dyskinesia, Drug-Induced	9.3%
314	Choroid Plexus Papilloma	9.2%
315	Cardiovascular Abnormalities	9.2%
316	Xeroderma	9.2%
317	Smith-Magenis syndrome	9.2%
318	Brain Concussion	9.1%
319	Meconium Aspiration Syndrome	9%
320	Sleep Wake Disorders	9%
321	May-Thurner Syndrome	8.9%
322	Autonomic Dysreflexia	8.9%
323	Complex Regional Pain Syndromes	8.9%
324	Coronary heart disease	8.8%
325	Myocardial Infarction	8.8%
326	Acute Coronary Syndrome	8.8%
327	Galactosemias	8.8%
328	Urea Cycle Disorders, Inborn	8.8%
329	Tyrosinemias	8.8%
330	Hypotension, Orthostatic	8.7%
331	Post-Exercise Hypotension	8.7%
332	Neonatal Abstinence Syndrome	8.7%
333	Dural Arteriovenous Fistula	8.7%
334	Central Nervous System Bacterial Infections	8.7%
335	Mesenteric vascular insufficiency	8.7%
336	Meningitis, Cryptococcal	8.6%
337	Scrapie	8.5%
338	Central Cord Syndrome	8.5%
339	Meningitis, Listeria	8.5%
340	Meningitis, Haemophilus	8.5%
341	Meningitis, Pneumococcal	8.5%
342	Angioedema	8.5%
343	Colitis, Ischemic	8.5%
344	Syphilis, Congenital	8.5%
345	Chorea	8.4%
346	Polyarteritis Nodosa	8.4%
347	Takayasu Arteritis	8.4%
348	Menkes Kinky Hair Syndrome	8.3%
349	West Nile Fever	8.3%
350	Central Nervous System Cysts	8.3%
351	Alice in Wonderland Syndrome	8.3%
352	Acromegaly	8.2%
353	Aneurysm, Dissecting	7.9%
354	Arteriosclerosis	7.9%
355	Arteritis	7.9%
356	Embolism	7.9%
357	Erythromelalgia	7.9%
358	Fibromuscular Dysplasia	7.9%
359	Malignant Hypertension	7.9%
360	Raynaud Disease	7.9%
361	Thromboembolism	7.9%
362	Thrombosis	7.9%
363	Essential Hypertension	7.9%
364	Aneurysm, Ruptured	7.9%
365	Iliac Aneurysm	7.9%
366	Pulmonary artery stenosis	7.9%
367	White Coat Hypertension	7.9%
368	Systemic Vasculitis	7.9%
369	Embolus	7.9%
370	Tuberous Sclerosis	7.9%
371	Homocystinuria	7.9%
372	Leigh Disease	7.8%
373	Hydranencephaly	7.8%
374	Neural Tube Defects	7.8%
375	Tethered Cord Syndrome	7.8%
376	Iniencephaly	7.8%
377	Craniorachischisis	7.8%
378	Exencephaly	7.8%
379	Septo-Optic Dysplasia	7.8%
380	Cortical Dysplasia	7.8%
381	Malformations of Cortical Development	7.8%
382	Aicardi's syndrome	7.7%
383	Peripheral Nerve Injuries	7.7%
384	Guillain-Barre Syndrome	7.7%
385	Myasthenia Gravis	7.6%
386	Kounis Syndrome	7.6%
387	Congenital Hyperinsulinism	7.5%
388	Angina Pectoris	7.5%
389	Torticollis	7.4%
390	Angioedemas, Hereditary	7.4%
391	Lambert-Eaton Myasthenic Syndrome	7.3%
392	Alstrom Syndrome	7.3%
393	Zellweger Syndrome	7.3%
394	Holoprosencephaly	7.2%
395	Lemierre Syndrome	7.1%
396	Embolism, Amniotic Fluid	7.1%
397	Charcot-Marie-Tooth Disease	6.9%
398	Heart Diseases	6.8%
399	Deformity	6.8%
400	Genetic Diseases, Inborn	6.8%
401	Sleep Disorders, Circadian Rhythm	6.8%
402	CREST Syndrome	6.8%
403	Glycogen storage disease type II	6.7%
404	Dysautonomia	6.7%
405	Paralysis, Obstetric	6.7%
406	Retinal Artery Occlusion	6.7%
407	Retinal Vasculitis	6.7%
408	Hypertensive Retinopathy	6.7%
409	Vagus Nerve Disorder	6.7%
410	Glossopharyngeal Neuralgia	6.7%
411	Abducens Nerve Diseases	6.7%
412	Heavy Metal Poisoning, Nervous System	6.7%
413	Myasthenic Syndromes, Congenital	6.7%
414	Neuromuscular Junction Diseases	6.7%
415	Tauopathies	6.7%
416	Trochlear Nerve Diseases	6.7%
417	Peripheral Nervous System Diseases	6.7%
418	Botulism	6.6%
419	Anterior Compartment Syndrome	6.6%
420	Progressive bulbar palsy	6.6%
421	Vasculitis, Leukocytoclastic, Cutaneous	6.6%
422	Gastric Antral Vascular Ectasia	6.6%
423	Carbamoyl-Phosphate Synthase I Deficiency Disease	6.6%
424	Abdominal Compartment Syndrome	6.6%
425	Bulbar palsy	6.6%
426	Cri-du-Chat Syndrome	6.6%
427	Down Syndrome	6.6%
428	Trisomy 21	6.6%
429	Varicose Ulcer	6.6%
430	Olfactory Nerve Injuries	6.6%
431	Primary Graft Dysfunction	6.6%
432	Ichthyosis, X-Linked	6.5%
433	Causalgia	6.5%
434	Neuromyelitis Optica	6.5%
435	Coronary Occlusion	6.5%
436	Microvascular Angina	6.5%
437	Coronary Stenosis	6.5%
438	ST segment elevation myocardial infarction	6.5%
439	Tuberculosis, Central Nervous System	6.5%
440	Marfan Syndrome	6.4%
441	Nelson Syndrome	6.4%
442	Prolactinoma	6.3%
443	Growth Hormone-Secreting Pituitary Adenoma	6.3%
444	Myotonic Dystrophy	6.3%
445	Dextrocardia	6.2%
446	Tricuspid Atresia	6.2%
447	Arrhythmogenic Right Ventricular Dysplasia	6.2%
448	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	6.1%
449	Anencephaly	6.1%
450	Pseudoxanthoma Elasticum	6%
451	Tardive Dyskinesia	6%
452	Cockayne Syndrome	5.9%
453	Williams Syndrome	5.9%
454	Arteriosclerosis Obliterans	5.9%
455	Atherosclerosis	5.9%
456	Air Embolism	5.9%
457	Endarteritis	5.9%
458	Ophthalmia Neonatorum	5.9%
459	Venous Thrombosis	5.9%
460	Deep Vein Thrombosis	5.9%
461	Venous Thromboembolism	5.9%
462	Prader-Willi Syndrome	5.8%
463	Facial Nerve Injuries	5.8%
464	Horner Syndrome	5.8%
465	Myotonia Congenita	5.8%
466	Fetal Diseases	5.7%
467	Myopathy	5.7%
468	Pregnancy Complications, Cardiovascular	5.7%
469	Optic Neuropathy	5.7%
470	Mesenteric Vascular Occlusion	5.7%
471	Mucocutaneous Lymph Node Syndrome	5.7%
472	Diabetic Retinopathy	5.7%
473	Rubinstein-Taybi Syndrome	5.7%
474	Beckwith-Wiedemann Syndrome	5.7%
475	Livedo Reticularis	5.7%
476	Wolf-Hirschhorn Syndrome	5.7%
477	Renal hypertension	5.6%
478	Multiple Sclerosis	5.6%
479	Renal Artery Obstruction	5.6%
480	Renal Artery Stenosis	5.6%
481	Neuroaspergillosis	5.6%
482	Facial Nerve Diseases	5.6%
483	Craniocerebral Trauma	5.6%
484	Parasomnia	5.6%
485	Dyssomnias	5.6%
486	Kartagener Syndrome	5.6%
487	Hemangioma, Cavernous	5.6%
488	Shock, Cardiogenic	5.6%
489	Scurvy	5.6%
490	Angina, Unstable	5.6%
491	Vestibulocochlear Nerve Diseases	5.6%
492	Decerebrate State	5.6%
493	Hemiparesis	5.6%
494	Meningism	5.6%
495	Paresis	5.6%
496	Seizures	5.6%
497	Sensation Disorders	5.6%
498	Central Nervous System Neoplasms	5.6%
499	Complex partial seizures	5.6%
500	Monoparesis	5.6%
501	Neurogenic Inflammation	5.6%
502	Gait Disorders, Neurologic	5.6%
503	Neuromuscular Manifestations	5.6%
504	Sweating, Gustatory	5.5%
505	Auriculotemporal Syndrome	5.5%
506	Gaucher Disease	5.5%
507	Reflex Sympathetic Dystrophy	5.5%
508	Nocturnal Myoclonus Syndrome	5.5%
509	Fragile X Syndrome	5.4%
510	Coronary Restenosis	5.4%
511	Sjogren-Larsson Syndrome	5.4%
512	Classical Lissencephalies and Subcortical Band Heterotopias	5.3%
513	Behcet Syndrome	5.3%
514	Myasthenia Gravis, Autoimmune, Experimental	5.2%
515	Aortic coarctation	5.2%
516	Cor Triatriatum	5.2%
517	Coronary Vessel Anomalies	5.2%
518	Patent ductus arteriosus	5.2%
519	Ebstein Anomaly	5.2%
520	Heart Septal Defects	5.2%
521	Tetralogy of Fallot	5.2%
522	Transposition of Great Vessels	5.2%
523	Hypoplastic Left Heart Syndrome	5.2%
524	Jet Lag Syndrome	5.1%
525	Pseudorabies	5.1%
526	Tay-Sachs Disease	5%
527	Amyloid Neuropathies, Familial	5%
528	Ophthalmoplegia	5%
529	External Ophthalmoplegia	5%
530	Intermittent Claudication	5%
531	Pulmonary Embolism	5%
532	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	5%
533	Ischemic contracture	5%
534	Cryoglobulinemia	4.9%
535	Meningomyelocele	4.9%
536	Spina Bifida	4.9%
537	No-Reflow Phenomenon	4.9%
538	Pupil Disorders	4.9%
539	Neurobehavioral Manifestations	4.9%
540	Nesidioblastosis	4.9%
541	Diabetic Foot	4.9%
542	Neurosyphilis	4.9%
543	Niemann-Pick Disease, Type C	4.8%
544	Paraneoplastic Encephalomyelitis	4.8%
545	Uveomeningoencephalitic Syndrome	4.8%
546	CHARGE Syndrome	4.8%
547	Muscular Dystrophy	4.7%
548	Vertigo	4.7%
549	Alcohol-Induced Disorders, Nervous System	4.7%
550	Hyperkeratosis, Epidermolytic	4.7%
551	Acrodynia	4.7%
552	Noonan Syndrome	4.6%
553	Angina Pectoris, Variant	4.6%
554	Neuronal Ceroid-Lipofuscinoses	4.5%
555	Long QT Syndrome	4.5%
556	Muscular Dystrophy, Duchenne	4.5%
557	Vocal Cord Paralysis	4.5%
558	Ectodermal Dysplasia	4.4%
559	Aplasia Cutis Congenita	4.4%
560	Aortic Valve Stenosis	4.4%
561	Cardiomyopathy, Dilated	4.4%
562	Pulmonary Valve Stenosis	4.4%
563	Purpura, Hyperglobulinemic	4.3%
564	Brachial Plexus Neuritis	4.3%
565	Neuralgic Amyotrophy	4.3%
566	Lyme Neuroborreliosis	4.3%
567	Voice Disorders	4.2%
568	Voice Disturbance	4.2%
569	Meningocele	4.2%
570	Encephalocele	4.2%
571	Malaria, Cerebral	4.2%
572	Duane Retraction Syndrome	4.2%
573	Bacterial Endocarditis	4.2%
574	Nail-Patella Syndrome	4.2%
575	Wolff-Parkinson-White Syndrome	4.2%
576	Neurocysticercosis	4.2%
577	Hypertension, Renovascular	4.2%
578	Rett Syndrome	4.2%
579	Hereditary Angioedema Type III	4.2%
580	Hereditary Angioedema Types I and II	4.2%
581	Hepatic Vein Thrombosis	4.1%
582	Budd-Chiari Syndrome	4.1%
583	Waterhouse-Friderichsen Syndrome	4.1%
584	Pulmonary Infarction	4.1%
585	Cerebrospinal Fluid Otorrhea	4.1%
586	Cerebrospinal Fluid Rhinorrhea	4.1%
587	Neuritis, Autoimmune, Experimental	4.1%
588	Gait Ataxia	4.1%
589	Abnormalities, Drug-Induced	4%
590	Cardiac Tamponade	4%
591	Endocarditis	4%
592	Cardiac Arrest	4%
593	Heart failure	4%
594	Pericardial effusion	4%
595	Pericarditis	4%
596	Pneumopericardium	4%
597	Cor pulmonale	4%
598	Situs Inversus	4%
599	Ventricular Outflow Obstruction	4%
600	Ventricular Dysfunction	4%
601	Cardiomyopathies	4%
602	Pleuropericarditis	4%
603	Turner Syndrome	4%
604	Coma, Post-Head Injury	4%
605	Waldenstrom Macroglobulinemia	3.9%
606	Multiple Myeloma	3.9%
607	Neuritis	3.9%
608	Polyneuritis	3.9%
609	Radiculitis	3.9%
610	Polyneuropathy	3.9%
611	Mononeuritis	3.9%
612	Mononeuropathies	3.9%
613	Brachial Plexus Neuropathies	3.9%
614	Radiculopathy	3.9%
615	Mononeuropathy Multiplex	3.9%
616	Nerve Root Compression	3.9%
617	Aortopulmonary Septal Defect	3.9%
618	Double Outlet Right Ventricle	3.9%
619	Endocardial Cushion Defects	3.9%
620	Myocardial bridging	3.9%
621	Aorticopulmonary Septal Defect	3.9%
622	Alcohol Withdrawal Seizures	3.9%
623	Microcephaly	3.9%
624	Macrocephaly	3.9%
625	Optic Atrophy, Hereditary, Leber	3.9%
626	Ectopia Cordis	3.8%
627	Single umbilical artery	3.8%
628	Tarsal Tunnel Syndrome	3.8%
629	Cauda Equina Syndrome	3.8%
630	Heart Block	3.8%
631	Tachycardia	3.8%
632	Tachyarrhythmia	3.8%
633	Mucopolysaccharidosis II	3.8%
634	Familial Periodic Paralysis	3.7%
635	Multiple Sclerosis, Chronic Progressive	3.7%
636	Multiple Sclerosis, Relapsing-Remitting	3.7%
637	Reflex, Abnormal	3.7%
638	Hyporeflexia	3.7%
639	Hyperreflexia	3.7%
640	Porencephaly	3.6%
641	Akathisia	3.6%
642	Restlessness	3.6%
643	Psychomotor Agitation	3.6%
644	Hypertrophic Cardiomyopathy	3.5%
645	Hypertrophic obstructive cardiomyopathy	3.5%
646	Dermal Sinus	3.5%
647	Spina Bifida Cystica	3.5%
648	Spina Bifida Occulta	3.5%
649	Lissencephaly	3.5%
650	Polymicrogyria	3.5%
651	Pachygyria	3.5%
652	Schizencephaly	3.5%
653	Periventricular Nodular Heterotopia	3.5%
654	Granulomatosis with polyangiitis	3.5%
655	Optic Nerve Glioma	3.5%
656	Eye Abnormalities	3.4%
657	Neoplastic Syndromes, Hereditary	3.4%
658	Romano-Ward Syndrome	3.4%
659	Skin Abnormalities	3.4%
660	Cardiac Output, High	3.4%
661	Myocardial Stunning	3.4%
662	Lymphatic Abnormalities	3.4%
663	Low Cardiac Output Syndrome	3.4%
664	Congenital Microtia	3.4%
665	Truncus Arteriosus, Persistent	3.3%
666	Cardiomegaly	3.3%
667	Multiple Epiphyseal Dysplasia	3.3%
668	Myositis	3.3%
669	Optic Atrophy	3.3%
670	Optic Neuritis	3.3%
671	Osteochondrodysplasias	3.3%
672	Papilledema	3.3%
673	Pelger-Huet Anomaly	3.3%
674	Postpericardiotomy Syndrome	3.3%
675	Strabismus	3.3%
676	Tolosa-Hunt Syndrome	3.3%
677	Werner Syndrome	3.3%
678	Isaacs syndrome	3.3%
679	Arsenic Poisoning	3.3%
680	Myotonic Disorders	3.3%
681	Cardiac Hypertrophy	3.3%
682	Congenital diaphragmatic hernia	3.3%
683	Rheumatic Heart Disease	3.3%
684	Albinism	3.3%
685	Diabetic Neuropathies	3.3%
686	Facial Injuries	3.3%
687	Facial Neuralgia	3.3%
688	Diabetic Amyotrophy	3.3%
689	Diabetic Autonomic Neuropathy	3.3%
690	Sleep Talking	3.3%
691	Manganese Poisoning	3.3%
692	Sleep Disorders, Intrinsic	3.3%
693	Orthostatic intolerance	3.3%
694	Anemia, Sickle Cell	3.3%
695	Thalassemia	3.3%
696	Anosmia	3.3%
697	Ataxia	3.3%
698	Athetosis	3.3%
699	Catalepsy	3.3%
700	Dystonia	3.3%
701	Hemiplegia	3.3%
702	Locked-In Syndrome	3.3%
703	Meningeal Neoplasms	3.3%
704	Muscle Hypertonia	3.3%
705	Muscle hypotonia	3.3%
706	Myoclonus	3.3%
707	Myotonia	3.3%
708	Neuralgia	3.3%
709	Paraplegia	3.3%
710	Pseudobulbar Palsy	3.3%
711	Quadriplegia	3.3%
712	Spasm	3.3%
713	Spastic Paraplegia	3.3%
714	Status Epilepticus	3.3%
715	Taste Disorders	3.3%
716	Tremor	3.3%
717	POEMS Syndrome	3.3%
718	Monoplegia	3.3%
719	Hypokinesia	3.3%
720	Paraparesis	3.3%
721	Bradykinesia	3.3%
722	Waxy flexibility	3.3%
723	Action Tremor	3.3%
724	Resting Tremor	3.3%
725	Dysosmia	3.3%
726	Quadriparesis	3.3%
727	Mercury Poisoning, Nervous System	3.3%
728	Olfaction Disorders	3.3%
729	Myokymia	3.3%
730	Lead Poisoning, Nervous System	3.3%
731	Vestibular Neuronitis	3.3%
732	Somatosensory Disorders	3.3%
733	Neuropathic pain	3.3%
734	Hyperkinesia	3.3%
735	Intention tremor	3.3%
736	Rheumatoid Vasculitis	3.3%
737	Polycystic Kidney Diseases	3.3%
738	Carpal Tunnel Syndrome	3.3%
739	Welander Distal Myopathy	3.3%
740	Supravalvular aortic stenosis	3.3%
741	Lown-Ganong-Levine Syndrome	3.3%
742	Smith-Lemli-Opitz Syndrome	3.3%
743	Sick Sinus Syndrome	3.2%
744	neurofibroma	3.2%
745	Gait Apraxia	3.2%
746	Sciatica	3.2%
747	Primary Ciliary Dyskinesia	3%
748	Acoustic Neuroma	3%
749	Retinal Dysplasia	3%
750	Kearns-Sayre syndrome	3%
751	Aniridia	3%
752	Urogenital Abnormalities	3%
753	Dwarfism	2.9%
754	Epidermolysis Bullosa	2.9%
755	Maxillofacial Abnormalities	2.9%
756	Vision Disorders	2.9%
757	Metamorphopsia	2.9%
758	Visual Impairment	2.9%
759	Fibromyalgia	2.9%
760	Medial Tibial Stress Syndrome	2.9%
761	Facial Hemiatrophy	2.9%
762	Fetal Growth Retardation	2.9%
763	Melkersson-Rosenthal Syndrome	2.9%
764	Mitochondrial Myopathies	2.9%
765	Anisocoria	2.8%
766	Confusion	2.8%
767	Facial paralysis	2.8%
768	Lethargy	2.8%
769	Memory Disorders	2.8%
770	Muscle Cramp	2.8%
771	Osteogenesis Imperfecta	2.8%
772	Perceptual Disorders	2.8%
773	Psychomotor Disorders	2.8%
774	Tonic Pupil	2.8%
775	Eosinophilia-Myalgia Syndrome	2.8%
776	Anhedonia	2.8%
777	Disorientation	2.8%
778	Fetal Hypoxia	2.8%
779	Facial Paresis	2.8%
780	Memory Loss	2.8%
781	Hemisensory Neglect	2.8%
782	Dysacusis	2.8%
783	Fetal Alcohol Spectrum Disorders	2.8%
784	Sleep Bruxism	2.8%
785	Muscular Atrophy	2.8%
786	Respiratory Paralysis	2.8%
787	Tetany	2.8%
788	Adams-Stokes Syndrome	2.8%
789	Atrioventricular Block	2.8%
790	Bundle-Branch Block	2.8%
791	Atrial Premature Complexes	2.8%
792	Sinoatrial Block	2.8%
793	Tachycardia, Paroxysmal	2.8%
794	Supraventricular tachycardia	2.8%
795	Tachycardia, Ventricular	2.8%
796	Tachycardia, Reciprocating	2.8%
797	Kallmann Syndrome	2.8%
798	Cubital Tunnel Syndrome	2.8%
799	Hypokalemic periodic paralysis	2.6%
800	Aortic Valve Insufficiency	2.6%
801	Restrictive cardiomyopathy	2.6%
802	Endocardial Fibroelastosis	2.6%
803	Heart Rupture, Post-Infarction	2.6%
804	Mitral Valve Insufficiency	2.6%
805	Mitral Valve Stenosis	2.6%
806	Myocarditis	2.6%
807	Pericarditis, Constrictive	2.6%
808	Familial Mediterranean Fever	2.6%
809	Prune Belly Syndrome	2.6%
810	Pulmonary Valve Insufficiency	2.6%
811	Tricuspid Valve Insufficiency	2.6%
812	Tricuspid Valve Stenosis	2.6%
813	Twins, Conjoined	2.6%
814	Ventricular Dysfunction, Left	2.6%
815	Right Ventricular Dysfunction	2.6%
816	Endomyocardial Fibrosis	2.6%
817	Carditis	2.6%
818	Heart Failure, Systolic	2.6%
819	Heart Failure, Diastolic	2.6%
820	Waardenburg Syndrome	2.6%
821	Wiskott-Aldrich Syndrome	2.6%
822	Sciatic Neuropathy	2.6%
823	Ulnar Neuropathies	2.6%
824	Lesion of Sciatic Nerve	2.6%
825	Ulnar Neuritis	2.6%
826	Radial nerve compression	2.6%
827	Radial Tunnel Syndrome	2.6%
828	Peroneal Neuropathies	2.6%
829	Radial Neuropathy	2.6%
830	Median Neuropathy	2.6%
831	Sciatic Nerve Palsy	2.6%
832	Femoral Neuropathy	2.6%
833	Tibial Neuropathy	2.6%
834	Ulnar Nerve Palsy	2.6%
835	Postural Orthostatic Tachycardia Syndrome	2.6%
836	Radial nerve palsy	2.6%
837	Subacute Bacterial Endocarditis	2.5%
838	Autoimmune Lymphoproliferative Syndrome	2.5%
839	Consciousness Disorders	2.5%
840	Mental Retardation	2.5%
841	Muscle Weakness	2.5%
842	Depressed Level of Consciousness	2.5%
843	Mental deficiency	2.5%
844	Intellectual Disability	2.5%
845	Bell Palsy	2.5%
846	Catatonia	2.5%
847	Chorioamnionitis	2.5%
848	Herpes Zoster Oticus	2.5%
849	Aphonia	2.5%
850	Sleep Deprivation	2.5%
851	Dysphonia	2.5%
852	Carcinoid Heart Disease	2.4%
853	Sickle Cell Trait	2.4%
854	Polycystic Kidney, Autosomal Dominant	2.4%
855	Tachycardia, Atrioventricular Nodal Reentry	2.3%
856	Tachycardia, Ectopic Atrial	2.3%
857	Tachycardia, Ectopic Junctional	2.3%
858	Sinus Tachycardia	2.3%
859	Torsades de Pointes	2.3%
860	Accelerated Idioventricular Rhythm	2.3%
861	Acrocephalosyndactylia	2.3%
862	Anophthalmos	2.2%
863	Anus, Imperforate	2.2%
864	Microphthalmos	2.2%
865	Xeroderma Pigmentosum	2.2%
866	Limb Deformities, Congenital	2.2%
867	Craniofacial Abnormalities	2.2%
868	Anorectal Malformations	2.2%
869	Klinefelter Syndrome	2.2%
870	Abnormalities, Radiation-Induced	2.2%
871	Amino Acid Metabolism, Inborn Errors	2.2%
872	Sinus Arrhythmia	2.2%
873	Atrial Fibrillation	2.2%
874	Atrial Flutter	2.2%
875	Bloom Syndrome	2.2%
876	Carbohydrate Metabolism, Inborn Errors	2.2%
877	Edema, Cardiac	2.2%
878	Metal Metabolism, Inborn Errors	2.2%
879	Progeria	2.2%
880	Ventricular Fibrillation	2.2%
881	Lysosomal Storage Diseases	2.2%
882	Ventricular Flutter	2.2%
883	Parasystole	2.2%
884	Paroxysmal atrial fibrillation	2.2%
885	Cytochrome-c Oxidase Deficiency	2.2%
886	Peroxisomal Disorders	2.2%
887	Bradycardia	2.2%
888	Diabetic Cardiomyopathies	2.2%
889	Myalgia	2.2%
890	Cardiomyopathy, Alcoholic	2.2%
891	Esotropia	2.2%
892	Exotropia	2.2%
893	Sleep Apnea Syndromes	2.2%
894	Sudden Cardiac Death	2.2%
895	Polymyositis	2.2%
896	Left Ventricular Hypertrophy	2.2%
897	Right Ventricular Hypertrophy	2.2%
898	Chagas Cardiomyopathy	2.2%
899	Craniosynostosis	2.2%
900	Syndactyly	2.2%
901	Brachycephaly	2.2%
902	Disorders of Excessive Somnolence	2.2%
903	Sleep Initiation and Maintenance Disorders	2.2%
904	Night Terrors	2.2%
905	Somnambulism	2.2%
906	Trigeminal Nerve Disorder	2.2%
907	Transient Insomnia	2.2%
908	Sleep Paralysis	2.2%
909	Chronic Insomnia	2.2%
910	REM Sleep Behavior Disorder	2.2%
911	Hypersomnia	2.2%
912	Antley-Bixler Syndrome Phenotype	2.2%
913	Dysgeusia	2.2%
914	Formication	2.2%
915	Hyperalgesia	2.2%
916	Hyperesthesia	2.2%
917	Hypesthesia	2.2%
918	Language Disorders	2.2%
919	Numbness	2.2%
920	Paresthesia	2.2%
921	Paraparesis, Spastic	2.2%
922	Trismus	2.2%
923	Epilepsia Partialis Continua	2.2%
924	Hypogeusia	2.2%
925	Meningeal Carcinomatosis	2.2%
926	Brown-Sequard Syndrome	2.2%
927	Lockjaw	2.2%
928	Allodynia	2.2%
929	Lead Poisoning, Nervous System, Childhood	2.2%
930	Lead Poisoning, Nervous System, Adult	2.2%
931	Ageusia	2.2%
932	Alexia	2.2%
933	Dyslexia	2.2%
934	Basal Cell Nevus Syndrome	2%
935	Hoarseness	2%
936	Acute Chest Syndrome	2%
937	Alcohol Withdrawal Delirium	2%
938	Neurofibrosarcoma	2%
939	Aortic Valve Prolapse	2%
940	Tricuspid Valve Prolapse	2%
941	Takotsubo Cardiomyopathy	2%
942	Polyradiculopathy	2%
943	Hydrops Fetalis	1.9%
944	Cleft Palate	1.9%
945	Blepharophimosis	1.9%
946	Eye Injuries	1.9%
947	Laryngostenosis	1.9%
948	Mouth Abnormalities	1.9%
949	Cutis Laxa	1.9%
950	Esophageal Atresia	1.9%
951	Intestinal Atresia	1.9%
952	Horseshoe Kidney	1.9%
953	Pectus excavatum	1.9%
954	Klippel-Feil Syndrome	1.9%
955	Retinitis Pigmentosa	1.9%
956	Gastroschisis	1.9%
957	Synostosis	1.9%
958	Orbital Myositis	1.9%
959	Pigmentary retinopathy	1.9%
960	Acrodermatitis	1.9%
961	Lymphangiectasis, Intestinal	1.9%
962	Porokeratosis	1.9%
963	Gianotti-Crosti Syndrome	1.9%
964	Keratoderma, Palmoplantar	1.9%
965	Diplopia	1.9%
966	Muscle Rigidity	1.9%
967	Muscle Spasticity	1.9%
968	Scotoma	1.9%
969	Photophobia	1.9%
970	Cogwheel Rigidity	1.9%
971	Hemifacial Spasm	1.9%
972	Amaurosis	1.9%
973	Blindness	1.9%
974	Nuchal Rigidity	1.9%
975	Dyspnea, Paroxysmal	1.9%
976	Chronic granulomatous disease	1.9%
977	Pyomyositis	1.9%
978	Agnosia	1.9%
979	Apraxias	1.9%
980	Hallucinations	1.9%
981	Hemianopsia	1.9%
982	Hyperacusis	1.9%
983	Tinnitus	1.9%
984	Visual Agnosia	1.9%
985	Anosognosia	1.9%
986	Wernicke-Korsakoff Syndrome	1.9%
987	Phonophobia	1.9%
988	Hearing Loss	1.9%
989	Sarcopenia	1.9%
990	Jaw Abnormalities	1.8%
991	Poland Syndrome	1.8%
992	Mucopolysaccharidosis III	1.8%
993	Hyperphosphaturia	1.8%
994	Arthrogryposis	1.7%
995	Choanal Atresia	1.7%
996	Tracheobronchomegaly	1.7%
997	Laryngocele	1.7%
998	Choledochal Cyst	1.7%
999	Hermaphroditism	1.7%
1000	Disorders of Sex Development	1.7%
1001	Cryptorchidism	1.7%
1002	Porphyrias, Hepatic	1.7%
1003	Hypospadias	1.7%
1004	Amnesia	1.6%
1005	Delirium	1.6%
1006	Dissociative Amnesia	1.6%
1007	Color blindness	1.6%
1008	Global Amnesia	1.6%
1009	Peutz-Jeghers Syndrome	1.6%
1010	Thrombasthenia	1.6%
1011	Antithrombin III Deficiency	1.6%
1012	Protein C Deficiency	1.6%
1013	Afibrinogenemia	1.6%
1014	Amelia	1.6%
1015	Arachnodactyly	1.6%
1016	Ectromelia	1.6%
1017	Factor VII Deficiency	1.6%
1018	Factor X Deficiency	1.6%
1019	Factor XII Deficiency	1.6%
1020	Hemimelia	1.6%
1021	Hemophilia A	1.6%
1022	Phocomelia	1.6%
1023	Sirenomelia	1.6%
1024	Polydactyly	1.6%
1025	Brachydactyly	1.6%
1026	Plagiocephaly	1.6%
1027	Lower Extremity Deformities, Congenital	1.6%
1028	Activated Protein C Resistance	1.6%
1029	Upper Extremity Deformities, Congenital	1.6%
1030	Factor II deficiency	1.6%
1031	Factor VIII Deficiency	1.6%
1032	Factor V deficiency	1.6%
1033	Factor XI Deficiency	1.6%
1034	Hypoprothrombinemias	1.6%
1035	Meningioma	1.6%
1036	Fanconi Anemia	1.6%
1037	Alkaptonuria	1.6%
1038	Glycogen Storage Disease	1.6%
1039	Hypophosphatasia	1.6%
1040	Propionic acidemia	1.6%
1041	Sinus Arrest, Cardiac	1.6%
1042	Dihydropyrimidine Dehydrogenase Deficiency	1.6%
1043	Cystinosis	1.6%
1044	Sleep Apnea, Obstructive	1.6%
1045	Sleep Apnea, Central	1.6%
1046	Anemia, Diamond-Blackfan	1.6%
1047	Narcolepsy	1.6%
1048	Trigeminal Neuralgia	1.6%
1049	Kleine-Levin Syndrome	1.6%
1050	Agraphia	1.6%
1051	Anomia	1.6%
1052	Cluttering	1.6%
1053	Language Development Disorders	1.6%
1054	Speech Disorders	1.6%
1055	Syncope	1.6%
1056	Stupor	1.6%
1057	Dysgraphia	1.6%
1058	Presyncope	1.6%
1059	Dyslalia	1.6%
1060	Micrognathism	1.5%
1061	Pierre Robin Syndrome	1.5%
1062	Multiple Endocrine Neoplasia	1.5%
1063	Laryngomalacia	1.5%
1064	Pectus carinatum	1.5%
1065	Bladder Exstrophy	1.5%
1066	Congenital Hypothyroidism	1.5%
1067	Epispadias	1.5%
1068	Dermatitis, Atopic	1.5%
1069	Multicystic Dysplastic Kidney	1.5%
1070	Phantom pain	1.4%
1071	Phantom Limb Pain	1.4%
1072	Dental Enamel Hypoplasia	1.4%
1073	Eye Burns	1.4%
1074	Hypodontia	1.4%
1075	Macrostomia	1.4%
1076	Microstomia	1.4%
1077	Retrognathia	1.4%
1078	Craniofacial Dysostosis	1.4%
1079	Hypolipoproteinemias	1.4%
1080	Papillon-Lefevre Disease	1.4%
1081	Amaurosis Fugax	1.4%
1082	Blindness, Cortical	1.4%
1083	Dyscalculia	1.4%
1084	Hyperlipidemia, Familial Combined	1.4%
1085	Hyperlipoproteinemia Type III	1.4%
1086	Deafness	1.4%
1087	Hearing Loss, Sudden	1.4%
1088	Gerstmann Syndrome	1.4%
1089	Hearing Loss, Bilateral	1.4%
1090	Hearing Loss, High-Frequency	1.4%
1091	Hearing Loss, Mixed Conductive-Sensorineural	1.4%
1092	Prosopagnosia	1.4%
1093	Apraxia, Ideomotor	1.4%
1094	Charles Bonnet Syndrome	1.4%
1095	Hearing Loss, Unilateral	1.4%
1096	Complete Hearing Loss	1.4%
1097	Alien Hand Syndrome	1.4%
1098	Deaf Mutism	1.4%
1099	Glycogen Storage Disease Type I	1.4%
1100	Glycogen Storage Disease Type V	1.4%
1101	Cataplexy	1.3%
1102	Aphasia	1.3%
1103	Articulation Disorders	1.3%
1104	Echolalia	1.3%
1105	Stuttering	1.3%
1106	Dysphasia	1.3%
1107	Hyperandrogenism	1.3%
1108	Prognathism	1.3%
1109	Dermatomyositis	1.2%
1110	Corneal Scar	1.2%
1111	Platybasia	1.2%
1112	Gonadal Dysgenesis	1.2%
1113	Bronchomalacia	1.2%
1114	Adrenogenital Syndrome	1.2%
1115	Tracheomalacia	1.2%
1116	Ovotesticular Disorders of Sex Development	1.2%
1117	Lactose Intolerance	1.2%
1118	Variegate Porphyria	1.2%
1119	Acute intermittent porphyria	1.2%
1120	Porphyria Cutanea Tarda	1.2%
1121	Hyperhomocysteinemia	1.2%
1122	Retrograde amnesia	1.2%
1123	Amnesia, Anterograde	1.2%
1124	Renal Aminoacidurias	1.2%
1125	Fanconi Syndrome	1.2%
1126	Pseudohypoaldosteronism	1.2%
1127	Liddle Syndrome	1.2%
1128	Hyperlipoproteinemia Type IV	1.2%
1129	Hyperlipoproteinemia Type V	1.2%
1130	Dysarthria	1.2%
1131	Mutism	1.2%
1132	Selective Mutism	1.2%
1133	Hypoalphalipoproteinemias	1.2%
1134	Denys-Drash Syndrome	1.1%
1135	Gout	1.1%
1136	Multiple Endocrine Neoplasia Type 1	1.1%
1137	Pseudohypoparathyroidism	1.1%
1138	Nephroblastoma	1.1%
1139	Renal tubular acidosis	1.1%
1140	Alexia, Pure	1%
1141	Goldenhar Syndrome	1%
1142	Corneal Perforation	1%
1143	Mandibulofacial Dysostosis	1%
1144	Cystinuria	1%
1145	Adenomatous Polyposis Coli	1%
1146	Familial Hypophosphatemic Rickets	1%
1147	Talipes	0.9%
1148	Arthritis, Gouty	0.9%
1149	Glycosuria, Renal	0.9%
1150	Congenital clubfoot	0.9%
1151	Vertical Talus	0.9%

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