MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Liver diseases

(UMLS:C0023895)

Definition:: Pathological processes of the LIVER.
UMLS ID:: C0023895
MeSH ID:: D008107

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.552

Synonym(s)

Liver diseases

Disease of liver

Disease of liver, NOS

Disease;liver

Disorder of liver

HEPATOCELLULAR DISEASE

Hepatic Disorder

Hepatic disease

Hepatopathy

10.

LD - Liver disease

11.

LIVER DISEASE

12.

Liver Disease

13.

Liver Diseases

14.

Liver Disorder

15.

Liver Disorders

16.

Liver and Intrahepatic Bile Duct Disorder

17.

Liver disease

Associated Drug(s)

	Name	Reference(s)	Data Source
1	1,1,1,2-tetrafluoro-2-chloroethane	9284778	CTD
2	1,2,4,5-tetrachlorobenzene	1949037	CTD
3	1,2,4-trichlorobenzene	1949037	CTD
4	1,3-dibromobenzene	9010591	CTD
5	1,3-dichlorobenzene	1853346 8661352	CTD
6	1,4-dioxane	17897969	CTD
7	1-Naphthylisothiocyanate	17184895 23411599	CTD
8	2,2',3',4,4',5-hexachlorobiphenyl	20961953	CTD
9	2,2,4-trimethylpentane	1715830	CTD
10	2,2-dichloro-1,1,1-trifluoroethane	7817129 9284778	CTD
11	2,3',4,4',5-pentachlorobiphenyl	20961953	CTD
12	2,3,3',4,4'-pentachlorobiphenyl	20961953	CTD
13	2,4,5,2',4',5'-hexachlorobiphenyl	20961953	CTD
14	2,4,6-trihydroxyacetophenone	11879983	CTD
15	2-dichlorobenzene	View details 1853346 1949037 8440869 8661352	CTD
16	3,4,3',4'-tetrachlorobiphenyl	20961953	CTD
17	3,4,5,3',4',5'-hexachlorobiphenyl	20961953	CTD
18	3,4,5,3',4'-pentachlorobiphenyl	20961953	CTD
19	3,4-dihydroxyphenylethanol	19393637	CTD
20	4,4'-diaminodiphenylmethane	26396155	CTD
21	4-dichlorobenzene	View details 1715830 1949037 7801330 8661352	CTD
22	ABVD protocol	2427187	CTD
23	Acetaminophen	View details 2780509 3086971 3206528 3670965 7084806 7979097 11587558 12587719 12969438 16508148 16610002 16611625 16922458 19014921 19460945 19784758 23411599	CTD
24	Acetylcysteine	9581680 16922458	CTD
25	Acrylamide	19862503	CTD
26	Agent Orange	11399444	CTD
27	Alcohols	6685305 16865776 16922458	CTD
28	Alloxan	19393637	CTD
29	Alpha-Amanitin	18296417	CTD
30	Alprostadil	9088814	CTD
31	Amiodarone	3414648 8522712 8679841	CTD
32	Amoxicillin-Potassium Clavulanate Combination	14986274	CTD
33	Amphetamine	8099372	CTD
34	Antimony Sodium Gluconate	7570843	CTD
35	Arsenicals	11134558 18834867	CTD
36	Azathioprine	View details 1420764 2060883 3287514 15980758 17504943 18431703 18788068 20848502 21168244	CTD
37	Barbital	3206528	CTD
38	Benzo(a)pyrene	17569222	CTD
39	Bilirubin	18431703	CTD
40	Busulfan	10955873	CTD
41	Cadmium Compounds	23636881	CTD
42	Calcimycin	2332587	CTD
43	Cannabidiol	31499052	CTD
44	Capsaicin	16956363	CTD
45	Carbon Monoxide	17173083	CTD
46	Carbon Tetrachloride	View details 1012282 3442185 3494838 6516898 8390255 9059516 10404535 15720792 15830285 16246199 16964402 17285989 17569222 21250784	CTD
47	Carmustine	10918425	CTD
48	Catechin	19428341	CTD
49	Ceftazidime	21227004	CTD
50	Ceftriaxone	21227004	CTD
51	Celecoxib	19007904	CTD
52	Cephalexin	7479194	CTD
53	Chenodeoxycholic Acid	25344563	CTD
54	Chlorpromazine	1175890 14986274	CTD
55	Chlorpropamide	10216414	CTD
56	Chlortetracycline	5973157	CTD
57	Cholic Acid	8698195 25344563	CTD
58	Chromium	12324196	CTD
59	Cimetidine	6141900	CTD
60	Clindamycin	7089634	CTD
61	Clofibrate	View details 8994295 9207284 10550479 10569642	CTD
62	Clozapine	8121527	CTD
63	Colchicine	2566048 10455999 17497454	CTD
64	Copper Sulfate	21229307	CTD
65	Cyclophosphamide	9251722 17580253	CTD
66	Cyclosporine	10455999 12469693	CTD
67	Cyproterone Acetate	8181926	CTD
68	Cytarabine	3463209 6223674 7858489	CTD
69	D-Galactosamine	15946935	CTD
70	Dacarbazine	2707742 3802121	CTD
71	Dactinomycin	169340	CTD
72	Danazol	6102641 16710600	CTD
73	Dapsone	8698924 15947852 17053738	CTD
74	Daptomycin	18381844	CTD
75	Daunorubicin	2352357	CTD
76	Deferoxamine	11401411	CTD
77	Dexamethasone	6650953	CTD
78	Diclofenac	14566034 15834531 16867024	CTD
79	Didanosine	18261327	CTD
80	Diethylhexyl Phthalate	3206528 9207284	CTD
81	Diethylnitrosamine	View details 6149821 8994295 10550479 17034775 18397917	CTD
82	Diltiazem	1472086	CTD
83	Dinoprostone	15816358	CTD
84	Disopyramide	6834895 7351137	CTD
85	Docosahexaenoic Acids	17056761	CTD
86	Doxorubicin	View details 135666 11401411 19429242 19459743	CTD
87	Doxycycline	13130401	CTD
88	Enalapril	1880490	CTD
89	Enflurane	7647582	CTD
90	Estradiol	20337216	CTD
91	Estramustine	866798 11844837	CTD
92	Ethambutol	188103 10599213	CTD
93	Ethosuximide	6847455	CTD
94	Etoposide	7858489 10918425	CTD
95	Fenofibrate	9033862 18157972	CTD
96	Fenretinide	6226123	CTD
97	Floxuridine	2522675 2848277 8862076	CTD
98	Fluconazole	14966256 17580253	CTD
99	Fluorouracil	8862076 9382546	CTD
100	Flutamide	View details 10431581 10500955 11411099 13129633	CTD
101	Fluvoxamine	15349014	CTD
102	Folic Acid	16877991	CTD
103	Fosinopril	11941910	CTD
104	Furosemide	2894691 3148942	CTD
105	Gabexate	15830285	CTD
106	Haloperidol	595591	CTD
107	Halothane	View details 1035409 1119708 2589676 2818932 3689669 5595515 5757486 6008975 6141900 6685305 7286784 7817129	CTD
108	Homocysteine	23665415	CTD
109	Idarubicin	7858489	CTD
110	Imatinib Mesylate	17364993	CTD
111	Indomethacin	2112558 15784032	CTD
112	Isoflurane	7647582	CTD
113	Isoniazid	10599213	CTD
114	Itraconazole	10592406	CTD
115	Ketoconazole	2728148 8267481	CTD
116	Labetalol	8124849	CTD
117	Lincomycin	7089634	CTD
118	Mebendazole	21254932	CTD
119	Melatonin	16508148 17376055	CTD
120	Melphalan	10955873 12606622	CTD
121	Mercaptopurine	67817 1058041 21272804	CTD
122	Mercuric Chloride	21787585	CTD
123	Metformin	10216414	CTD
124	Methimazole	11193444 18383979	CTD
125	Methionine	616159 10231861	CTD
126	Methotrexate	View details 67817 1058041 5469272 7577576 25145655	CTD
127	Minocycline	10928400	CTD
128	Mitoxantrone	20427751	CTD
129	N-(2-hydroxyethyl)retinamide	6226123	CTD
130	N-Acetylcysteinamide	25922074	CTD
131	N-Methyl-3,4-methylenedioxyamphetamine	8099372	CTD
132	N-vinyl-2-pyrrolidinone	22037397	CTD
133	Nafenopin	9251722	CTD
134	Naproxen	16867024	CTD
135	Nevirapine	18261327	CTD
136	Nicardipine	1766214	CTD
137	Nicotine	15925865	CTD
138	Nifedipine	2332587	CTD
139	Nitrofurantoin	14966256	CTD
140	Oleanolic Acid	8847885 15720792	CTD
141	Oxygen	View details 24058562 25352008 27363631 28966130	CTD
142	PCB 180	20961953	CTD
143	Patulin	26584762	CTD
144	Penicillamine	21364284 24901380	CTD
145	Pentamidine	1519856	CTD
146	Phenobarbital	View details 3689669 6149821 9268606 9879813 19363144 22037397	CTD
147	Phenytoin	14986274	CTD
148	Piperonyl Butoxide	9268606 9879813	CTD
149	Piroxicam	16867024	CTD
150	Polychlorinated Dibenzodioxins	2472021 11399444	CTD
151	Polyvinyl Chloride	15211785 16270392	CTD
152	Prajmaline	1261401	CTD
153	Prednisone	1058041 8698924	CTD
154	Propofol	9875925 23353162	CTD
155	Propranolol	11193444	CTD
156	Quercetin	9581680 20620188	CTD
157	Resveratrol	View details 9581680 18277952 23353162 25352008	CTD
158	Rifampin	View details 188103 623706 694100 997458 4834100 8209524 10599213 13677879	CTD
159	Ritonavir	20003457	CTD
160	Rosiglitazone	14562008	CTD
161	Rotenone	28374803	CTD
162	S-Adenosylmethionine	1327655	CTD
163	Silymarin	17213517	CTD
164	Simvastatin	22031447	CTD
165	Sodium Fluoride	20859737	CTD
166	Stavudine	18261327	CTD
167	Streptozocin	View details 135666 199092 4352784 15384252 31499052	CTD
168	Sulfapral	4629449	CTD
169	Sulindac	View details 8256166 14566034 14986274 16867024	CTD
170	Tamoxifen	17431437	CTD
171	Tetrachloroethylene	17267091	CTD
172	Tetracycline	5875218	CTD
173	Thiabendazole	21513789	CTD
174	Thioacetamide	15158337 16337175 18374380	CTD
175	Thiotepa	10918425 10955873	CTD
176	Thyroxine	17230007	CTD
177	Ticlopidine	9798669	CTD
178	Tretinoin	9378467 18275266	CTD
179	Trichloroethylene	19367038	CTD
180	Trimethoprim, Sulfamethoxazole Drug Combination	80611 7479194 10877016	CTD
181	Trimethoprim	7479194	CTD
182	Tropisetron	23285267	CTD
183	Ursodeoxycholic Acid	View details 2391071 15802798 17888421 19493473 19811448 21115542	CTD
184	Valproic Acid	3092003 6772435	CTD
185	Vecuronium Bromide	8614883	CTD
186	Vincristine	169340	CTD
187	Vitamin A	10424294 16175620	CTD
188	Vitamin B 12	6533326	CTD
189	Vitamin E	18377885 21787585	CTD
190	Zidovudine	8004891	CTD
191	Zimeldine	6215083	CTD
192	Zinc Sulfate	16865776	CTD
193	aceclofenac	16867024	CTD
194	aflatoxin G1	17569222	CTD
195	allyl alcohol	26396155	CTD
196	anethole	2467866	CTD
197	asarone	8157216	CTD
198	astringin	22022464	CTD
199	baicalin	22019745	CTD
200	beta Carotene	10424294	CTD
201	breviscapine	27363631	CTD
202	caffeic acid phenethyl ester	18397917	CTD
203	cardamonin	28966130	CTD
204	chlorobenzene	1949037	CTD
205	chlorpyrifos-ethyl	15991261	CTD
206	clentiazem	1472086	CTD
207	clometacin	16867024	CTD
208	cobaltiprotoporphyrin	23525258	CTD
209	crocin	26584762	CTD
210	cyanoginosin LR	18296417	CTD
211	cypermethrin	15991261 21229307	CTD
212	diisodecyl phthalate	20358181	CTD
213	droxicam	16867024	CTD
214	echinacoside	17222497	CTD
215	ethyl tert-butyl ether	22102104	CTD
216	fanasil, pyrimethamine drug combination	3155635	CTD
217	fluindione	21284358	CTD
218	fosfestrol	4629449	CTD
219	hexabromobenzene	437040	CTD
220	isophorone	1715830	CTD
221	lathosterol	12189593	CTD
222	lead nitrate	21229307	CTD
223	lemon oil	1715830	CTD
224	liposomal amphotericin B	2332587	CTD
225	mancozeb	2792977	CTD
226	menthofuran	23106769	CTD
227	methanobactin	21364284	CTD
228	naringenin	16945181	CTD
229	nefazodone	18344530	CTD
230	nickel sulfate	15535990	CTD
231	nimesulide	16867024	CTD
232	notoginsenoside R1	18176958	CTD
233	pentachlorobenzene	1949037	CTD
234	perhexiline maleate	205835	CTD
235	propiconazole	19363144	CTD
236	pyrazinobutazone	2600947	CTD
237	reviparin	8623174	CTD
238	rofecoxib	15834531	CTD
239	rosmarinic acid	25455894	CTD
240	salvianolic acid	17244260	CTD
241	sirtinol	19448212	CTD
242	sodium bisulfide	24058562	CTD
243	sultamicillin	2686918	CTD
244	tenoxicam	16867024	CTD
245	tetrahydroneopterin	8390255	CTD
246	tipranavir	20003457	CTD
247	titanium dioxide	19501137	CTD
248	tizanidine	15834531	CTD
249	triadimefon	19363144	CTD
250	trovafloxacin	11549784 11549788	CTD
251	turmeric extract	View details 16956363 17569222 18377885 19459743	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Biliary Tract Diseases	33.3%
2	Gastrointestinal Diseases	33.3%
3	Pancreatic Diseases	33.3%
4	Zollinger-Ellison syndrome	24.3%
5	Proctocolitis	24.1%
6	Dysentery	23.8%
7	Enteritis	23.8%
8	Enterocolitis	23.8%
9	Esophagitis	23.8%
10	Gastritis	23.8%
11	Inflammatory Bowel Diseases	23.8%
12	Cholecystolithiasis	23.8%
13	Bile Duct Diseases	23.1%
14	Cholelithiasis	23.1%
15	Chylous Ascites	23.1%
16	Duodenitis	23.1%
17	Esophageal Diseases	23.1%
18	Gastroenteritis	23.1%
19	Ileitis	23.1%
20	Intestinal Diseases	23.1%
21	Pancreatic Insufficiency	23.1%
22	Pancreatitis	23.1%
23	Pneumoperitoneum	23.1%
24	Stomach Diseases	23.1%
25	Erosive Duodenitis	23.1%
26	Colitis	22.4%
27	Duodenogastric Reflux	22.4%
28	Peptic Ulcer	22.4%
29	Proctitis	22.4%
30	Choledocholithiasis	22.4%
31	Gastrointestinal Neoplasms	21.8%
32	Pancreatic Fistula	21.6%
33	Pouchitis	21.5%
34	Colorectal Neoplasms	21.4%
35	Digestive System Neoplasms	21.1%
36	Crohn Disease	20.9%
37	Duodenal Obstruction	20.9%
38	Enterocolitis, Neutropenic	20.9%
39	Necrotizing Enterocolitis	20.9%
40	Bile Duct Neoplasms	20.7%
41	gallbladder neoplasm	20.7%
42	Intestinal Neoplasms	20.7%
43	Stomach Neoplasms	20.7%
44	Duodenal Ulcer	20.2%
45	Peptic Ulcer Perforation	20.2%
46	Gastric ulcer	20.2%
47	Cecal Neoplasms	20.1%
48	Duodenal Neoplasms	20.1%
49	Mesenteric vascular insufficiency	20%
50	Esophageal Atresia	19.6%
51	Intestinal Atresia	19.6%
52	Mesenteric Vascular Occlusion	19.6%
53	Intestinal Fistula	19.5%
54	Enterocutaneous Fistula	19.5%
55	Anus Neoplasms	19.4%
56	Sigmoid Neoplasms	19.4%
57	Colonic Pseudo-Obstruction	19.2%
58	Rectal Fistula	19%
59	Anal Fistula	19%
60	Appendiceal Neoplasms	18.7%
61	Colonic Neoplasms	18.7%
62	Rectal Neoplasms	18.7%
63	Cecal Diseases	18.5%
64	Cholangitis	18.5%
65	Cholecystitis	18.5%
66	Cholestasis	18.5%
67	Colonic Diseases	18.5%
68	Common Bile Duct Diseases	18.5%
69	Esophageal Stenosis	18.5%
70	Ileal Diseases	18.5%
71	Intestinal Obstruction	18.5%
72	Intestinal Perforation	18.5%
73	Jejunal Diseases	18.5%
74	Pneumatosis Cystoides Intestinalis	18.5%
75	Rectal Diseases	18.5%
76	Gastric Dilatation	18.5%
77	Pancreatitis, Chronic	18.5%
78	Gastric outlet obstruction	18.5%
79	Cronkhite-Canada Syndrome	18.5%
80	Intestinal Polyposis	18.5%
81	Gastrointestinal Stromal Tumors	17.4%
82	Esophageal Neoplasms	17.1%
83	Peritoneal Neoplasms	17.1%
84	Appendicitis	16.5%
85	Cholestasis, Extrahepatic	16.4%
86	Biliary Dyskinesia	16.4%
87	Cholangitis, Sclerosing	16.4%
88	Colonic Diseases, Functional	16.4%
89	Esophageal motility disorders	16.4%
90	Fecal Incontinence	16.4%
91	Fecal Impaction	16.4%
92	Intussusception	16.4%
93	Mallory-Weiss Syndrome	16.4%
94	Megacolon	16.4%
95	Pyloric Stenosis	16.4%
96	Acalculous Cholecystitis	16.4%
97	Ileus	16.4%
98	Meconium ileus	16.4%
99	Choledochal Cyst	15.7%
100	Enterocolitis, Pseudomembranous	15.4%
101	pseudomembranous colitis	15.4%
102	Dysentery, Bacillary	15.4%
103	Esophageal Achalasia	15.3%
104	Anal Fissure	15.3%
105	Intestinal Pseudo-Obstruction	15.3%
106	Irritable Bowel Syndrome	15.3%
107	Superior Mesenteric Artery Syndrome	15.3%
108	Emphysematous Cholecystitis	15.3%
109	Neurogenic Bowel	15.3%
110	Sphincter of Oddi Dysfunction	15.3%
111	Anal Ulcer	15.3%
112	Colitis, Ischemic	15.3%
113	Pancreatic Cyst	15%
114	Anus, Imperforate	14.6%
115	Gastrointestinal Hemorrhage	14.6%
116	Hemoperitoneum	14.6%
117	Mesenteric Panniculitis	14.6%
118	Panniculitis, Peritoneal	14.6%
119	Peritonitis	14.6%
120	Peritoneal Fibrosis	14.6%
121	Encapsulating Peritoneal Sclerosis	14.6%
122	Anorectal Malformations	14.6%
123	Biliary Fistula	14.5%
124	Gastric Fistula	14.5%
125	Tuberculosis, Gastrointestinal	14.3%
126	Pancreatic Neoplasm	14.3%
127	Adenomatous Polyposis Coli	14.2%
128	Esophageal Perforation	12.8%
129	Intestinal Diseases, Parasitic	12.8%
130	Barrett Esophagus	12.2%
131	Deglutition Disorders	12.2%
132	Achlorhydria	11.9%
133	Esophageal and Gastric Varices	11.9%
134	Pancreatic Pseudocyst	11.9%
135	Gastric Antral Vascular Ectasia	11.9%
136	Peptic Ulcer Hemorrhage	11.8%
137	Gastroparesis	11.8%
138	Pancreatitis, Alcoholic	11.8%
139	Liver neoplasms	10.9%
140	Hemorrhoids	10.8%
141	Afferent Loop Syndrome	10.6%
142	Celiac Disease	10.6%
143	Short Bowel Syndrome	10.6%
144	Sprue, Tropical	10.6%
145	Steatorrhea	10.6%
146	Rectocele	10.6%
147	Sprue	10.6%
148	Diverticulitis	10.5%
149	Dumping Syndrome	10.5%
150	Rectal Prolapse	10.5%
151	Pruritus Ani	9.9%
152	Laryngopharyngeal Reflux	9.9%
153	Melena	8.8%
154	Cystic Fibrosis	8.8%
155	Hematemesis	8.6%
156	insulinoma	8.5%
157	Gastrinoma	8.5%
158	Glucagonoma	8.5%
159	Congenital Hyperinsulinism	8.5%
160	Carcinoma, Pancreatic Ductal	8.4%
161	Giardiasis	8.1%
162	Diverticulum	7.9%
163	Diverticulosis	7.9%
164	Vipoma	7.4%
165	Biliary cirrhosis	7.4%
166	Hepatocellular Adenoma	6.8%
167	Nesidioblastosis	6.8%
168	Peutz-Jeghers Syndrome	6.2%
169	Lactose Intolerance	6.1%
170	Liver Neoplasms, Experimental	5.7%
171	Cryptosporidiosis	4.4%
172	CREST Syndrome	4.1%

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