MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Colonic Diseases, Functional

(UMLS:C0009374)

Definition:: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.
UMLS ID:: C0009374
MeSH ID:: D003109

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405.469.158.272

Synonym(s)

Colonic Diseases, Functional

colon; disease, functional

disease (or disorder); colon, functional

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Meprobamate	3489028	CTD
2	Nifedipine	2716305	CTD
3	tridihexethyl	3489028	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Megacolon	48.4%
2	Colitis	42.4%
3	Proctocolitis	36%
4	Cecal Diseases	34.4%
5	Ileal Diseases	34.4%
6	Intestinal Obstruction	34.4%
7	Intestinal Perforation	34.4%
8	Jejunal Diseases	34.4%
9	Pneumatosis Cystoides Intestinalis	34.4%
10	Rectal Diseases	34.4%
11	Cronkhite-Canada Syndrome	34.4%
12	Intestinal Polyposis	34.4%
13	Dysentery	33%
14	Enteritis	33%
15	Enterocolitis	33%
16	Inflammatory Bowel Diseases	33%
17	Colorectal Neoplasms	30.3%
18	Duodenal Obstruction	30.1%
19	Duodenitis	27.4%
20	Ileitis	27.4%
21	Erosive Duodenitis	27.4%
22	Esophageal Diseases	25.4%
23	Gastroenteritis	25.4%
24	Stomach Diseases	25.4%
25	Duodenogastric Reflux	25%
26	Peptic Ulcer	25%
27	Proctitis	25%
28	Sigmoid Neoplasms	24.8%
29	Intestinal Diseases, Parasitic	24.7%
30	Zollinger-Ellison syndrome	24%
31	Colitis, Ischemic	23.5%
32	Fecal Incontinence	22.6%
33	Fecal Impaction	22.6%
34	Intussusception	22.6%
35	Ileus	22.6%
36	Meconium ileus	22.6%
37	Mesenteric vascular insufficiency	22.2%
38	Intestinal Atresia	21.8%
39	Mesenteric Vascular Occlusion	21.8%
40	Intestinal Neoplasms	21.7%
41	Intestinal Fistula	21.7%
42	Enterocutaneous Fistula	21.7%
43	Crohn Disease	21.5%
44	Enterocolitis, Neutropenic	21.5%
45	Necrotizing Enterocolitis	21.5%
46	Colonic Neoplasms	20.7%
47	Pouchitis	20.3%
48	Rectal Fistula	20.1%
49	Anal Fistula	20.1%
50	Esophagitis	19.8%
51	Gastritis	19.8%
52	Cecal Neoplasms	19.3%
53	Duodenal Neoplasms	19.3%
54	Appendicitis	18.9%
55	Duodenal Ulcer	17.6%
56	Peptic Ulcer Perforation	17.6%
57	Gastric ulcer	17.6%
58	Adenomatous Polyposis Coli	17.1%
59	Gastrointestinal Neoplasms	17.1%
60	Gastrointestinal Hemorrhage	16.9%
61	Anal Fissure	16.8%
62	Intestinal Pseudo-Obstruction	16.8%
63	Superior Mesenteric Artery Syndrome	16.8%
64	Anal Ulcer	16.8%
65	Tuberculosis, Gastrointestinal	16.5%
66	Biliary Tract Diseases	16.4%
67	Liver diseases	16.4%
68	Pancreatic Diseases	16.4%
69	Enterocolitis, Pseudomembranous	16.1%
70	pseudomembranous colitis	16.1%
71	Dysentery, Bacillary	16.1%
72	Hemorrhoids	15.6%
73	Afferent Loop Syndrome	15.2%
74	Celiac Disease	15.2%
75	Short Bowel Syndrome	15.2%
76	Sprue, Tropical	15.2%
77	Steatorrhea	15.2%
78	Rectocele	15.2%
79	Sprue	15.2%
80	Rectal Prolapse	15.1%
81	Anus Neoplasms	14.9%
82	Esophageal Stenosis	14.8%
83	Gastric Dilatation	14.8%
84	Gastric outlet obstruction	14.8%
85	Appendiceal Neoplasms	14.3%
86	Rectal Neoplasms	14.3%
87	Stomach Neoplasms	13.8%
88	Esophageal and Gastric Varices	13.2%
89	Giardiasis	11.9%
90	Esophageal Atresia	11.8%
91	Esophageal Neoplasms	11.5%
92	Pruritus Ani	11.4%
93	Digestive System Neoplasms	10.8%
94	Esophageal Perforation	10.6%
95	Barrett Esophagus	10.1%
96	Deglutition Disorders	10.1%
97	Achlorhydria	9.9%
98	Gastric Antral Vascular Ectasia	9.9%
99	Gastrointestinal Stromal Tumors	9.8%
100	Peptic Ulcer Hemorrhage	9.8%
101	Gastroparesis	9.8%
102	Esophageal motility disorders	9.7%
103	Mallory-Weiss Syndrome	9.7%
104	Pyloric Stenosis	9.7%
105	Colonic Pseudo-Obstruction	9.3%
106	Peutz-Jeghers Syndrome	9.2%
107	Lactose Intolerance	9.1%
108	Liver neoplasms	8.5%
109	Bile Duct Diseases	8.5%
110	Cholelithiasis	8.5%
111	Chylous Ascites	8.5%
112	Fatty Liver	8.5%
113	Hepatitis	8.5%
114	Portal Hypertension	8.5%
115	Liver Cirrhosis	8.5%
116	Pancreatic Fistula	8.5%
117	Pancreatic Insufficiency	8.5%
118	Pancreatitis	8.5%
119	Pneumoperitoneum	8.5%
120	Focal Nodular Hyperplasia	8.5%
121	Hepatic Insufficiency	8.5%
122	Steatohepatitis	8.5%
123	Melena	7.5%
124	Hematemesis	7.3%
125	Esophageal Achalasia	7.2%
126	Peritoneal Neoplasms	6.8%
127	Cryptosporidiosis	6.7%
128	Cholecystolithiasis	6.6%
129	Diverticulitis	6.5%
130	Dumping Syndrome	6.5%
131	Biliary cirrhosis	6.1%
132	Liver Diseases, Parasitic	6%
133	Bile Duct Neoplasms	5.9%
134	gallbladder neoplasm	5.9%
135	Hepatic Veno-Occlusive Disease	5.7%
136	Pancreatic Cyst	5.7%
137	Peliosis Hepatis	5.7%
138	Hepatopulmonary Syndrome	5.7%
139	Pancreatic Neoplasm	5.7%
140	Anus, Imperforate	5.6%
141	Hemoperitoneum	5.6%
142	Hepatomegaly	5.6%
143	Mesenteric Panniculitis	5.6%
144	Panniculitis, Peritoneal	5.6%
145	Peritonitis	5.6%
146	Peritoneal Fibrosis	5.6%
147	Encapsulating Peritoneal Sclerosis	5.6%
148	Anorectal Malformations	5.6%
149	Biliary Fistula	5.6%
150	Gastric Fistula	5.6%
151	Hepatic Vein Thrombosis	5.5%
152	Liver Abscess	5.5%
153	Budd-Chiari Syndrome	5.5%
154	Choledochal Cyst	5.4%
155	Choledocholithiasis	5.4%
156	Diverticulum	5%
157	Diverticulosis	5%
158	Cholangitis	4.9%
159	Cholecystitis	4.9%
160	Cholestasis	4.9%
161	Common Bile Duct Diseases	4.9%
162	Hepatitis, Chronic	4.9%
163	Liver Failure	4.9%
164	Pancreatitis, Chronic	4.9%
165	Non-alcoholic Fatty Liver Disease	4.9%
166	Chronic active hepatitis	4.9%
167	Fatty Liver, Alcoholic	4.9%
168	Hepatitis, Alcoholic	4.9%
169	Liver Cirrhosis, Alcoholic	4.9%
170	Chemical and Drug Induced Liver Injury	4.3%
171	Hepatorenal Syndrome	4.2%
172	Laryngopharyngeal Reflux	4.1%
173	Hepatocellular Adenoma	3.9%
174	Hepatitis, Animal	3.5%
175	Hepatitis, Viral, Human	3.5%
176	Cystic Fibrosis	3.5%
177	Porphyrias, Hepatic	3.4%
178	Congenital Hyperinsulinism	3.4%
179	Liver Abscess, Amebic	3.3%
180	Liver Neoplasms, Experimental	3.3%
181	Liver Cirrhosis, Experimental	3.3%
182	Pancreatic Pseudocyst	3.3%
183	Pancreatitis, Alcoholic	3.3%
184	Cholestasis, Extrahepatic	3.2%
185	Biliary Dyskinesia	3.2%
186	Cholangitis, Sclerosing	3.2%
187	Liver Failure, Acute	3.2%
188	Acalculous Cholecystitis	3.2%
189	End Stage Liver Disease	3.2%
190	Fascioliasis	2.5%
191	Echinococcosis, Hepatic	2.5%
192	Chemical and Drug Induced Liver Injury, Chronic	2.5%
193	Reye Syndrome	2.5%
194	Carcinoma, Pancreatic Ductal	2.4%
195	Massive Hepatic Necrosis	2.4%
196	Emphysematous Cholecystitis	2.4%
197	Sphincter of Oddi Dysfunction	2.4%
198	Hepatitis B, Chronic	2.3%
199	Hepatitis C, Chronic	2.3%
200	Autoimmune hepatitis	2.2%
201	CREST Syndrome	2.1%
202	Nesidioblastosis	1.9%
203	Variegate Porphyria	1.9%
204	Acute intermittent porphyria	1.9%
205	Porphyria Cutanea Tarda	1.9%
206	insulinoma	1.8%
207	Gastrinoma	1.8%
208	Glucagonoma	1.8%
209	Hepatitis, Viral, Animal	1.8%
210	Hepatitis E	1.7%
211	Hepatitis B	1.7%
212	Hepatitis C	1.7%
213	Hepatitis A	1.7%
214	Hepatic Encephalopathy	1.6%
215	Vipoma	1.6%
216	Zellweger Syndrome	1.5%
217	Hepatolenticular Degeneration	1.4%
218	Rift Valley Fever	0.7%

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