lenvatinib
(WOSKHXYHFSIKNG-UHFFFAOYSA-N)
Structure
- SMILES
- COc1cc2nccc(c2cc1C(=O)N)Oc1ccc(c(c1)Cl)NC(=O)NC1CC1
- Type(s)
- Approved; Investigational
- ATC code(s)
- L01XE29
- Molecular Formula:
- C21H19ClN4O4
- Molecular Weight:
- 426.853
- Log P:
- 5.2361
- Hydrogen Bond Acceptor:
- 8
- Hydrogen Bond Donor:
- 3
- TPSA:
- 115.57
- CAS Number(s):
- 417716-92-8
Synonym(s)
1.
lenvatinib
2.
4-(3-chloro-4-((cyclopropylaminocarbonyl)amino)phenoxy)-7-methoxy-6-quinolinecarboxamide
3.
4-(3-chloro-4-(N'-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide
4.
E 7080
5.
E-7080
6.
Lenvima
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Fatigue | FAERS: 293 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 2 | Malignant neoplasm progression | FAERS: 292 | US FAERS | |
| 3 | Proteinuria | FAERS: 207 | US FAERS | |
| 4 | Nausea | FAERS: 188 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 5 | Malaise | FAERS: 184 | US FAERS | |
| 6 | Vomiting | FAERS: 157 | US FAERS | |
| 7 | Dehydration | FAERS: 140 | US FAERS | |
| 8 | Hepatic Encephalopathy | FAERS: 139 | US FAERS | |
| 9 | Asthenia | FAERS: 115 | US FAERS | |
| 10 | Weight decreased | FAERS: 102 | US FAERS | |
| 11 | Headache | FAERS: 99 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | Stomatitis | FAERS: 79 | US FAERS | |
| 13 | Dysphonia | FAERS: 76 | US FAERS | |
| 14 | Ascites | FAERS: 75 | US FAERS | |
| 15 | Pneumonia | FAERS: 74 | US FAERS | |
| 16 | Hypothyroidism | FAERS: 62 | US FAERS | |
| 17 | Arthralgia | FAERS: 55 | US FAERS | |
| 18 | Dizziness | FAERS: 55 | US FAERS | |
| 19 | Abdominal Pain | FAERS: 52 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 20 | Constipation | FAERS: 52 | US FAERS | |
| 21 | Back Pain | FAERS: 50 | US FAERS | |
| 22 | Ammonia increased | FAERS: 46 | US FAERS | |
| 23 | Pain | FAERS: 43 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 24 | Aspartate Aminotransferase Increased | FAERS: 37 | US FAERS | |
| 25 | Epistaxis | FAERS: 37 | US FAERS | |
| 26 | jaundice | FAERS: 33 | US FAERS | |
| 27 | Thrombocytopenia | FAERS: 32 | US FAERS | |
| 28 | Cholecystitis | FAERS: 31 | US FAERS | |
| 29 | Cerebrovascular accident | FAERS: 30 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 30 | Cholangitis | FAERS: 30 | US FAERS | |
| 31 | Oropharyngeal pain | FAERS: 30 | US FAERS | |
| 32 | Pneumothorax | FAERS: 29 | US FAERS | |
| 33 | Alanine Aminotransferase Increased | FAERS: 28 | US FAERS | |
| 34 | Tumour haemorrhage | FAERS: 28 | US FAERS | |
| 35 | Oral pain | FAERS: 27 | US FAERS | |
| 36 | Myalgia | FAERS: 26 | US FAERS | |
| 37 | Myocardial Infarction | FAERS: 26 | US FAERS | |
| 38 | Acute kidney injury | FAERS: 25 | US FAERS | |
| 39 | Cerebral Infarction | FAERS: 25 | US FAERS | |
| 40 | Chest Pain | FAERS: 24 | US FAERS | |
| 41 | Urinary tract infection | FAERS: 24 | US FAERS | |
| 42 | Peripheral swelling | FAERS: 23 | US FAERS | |
| 43 | Product use in unapproved indication | FAERS: 23 | US FAERS | |
| 44 | Sepsis | FAERS: 23 | US FAERS | |
| 45 | Abdominal discomfort | FAERS: 22 | US FAERS | |
| 46 | Dysgeusia | FAERS: 22 | US FAERS | |
| 47 | Hypotension | FAERS: 22 | US FAERS | |
| 48 | Blood creatinine increased | FAERS: 21 | US FAERS | |
| 49 | Dry skin | FAERS: 21 | US FAERS | |
| 50 | Blood thyroid stimulating hormone increased | FAERS: 20 | US FAERS | |
| 51 | Neck Pain | FAERS: 20 | US FAERS | |
| 52 | Pancreatitis | FAERS: 19 | US FAERS | |
| 53 | Posterior reversible encephalopathy syndrome | FAERS: 19 | US FAERS | |
| 54 | Bone pain | FAERS: 18 | US FAERS | |
| 55 | White blood cell count decreased | FAERS: 18 | US FAERS | |
| 56 | Pulmonary Embolism | FAERS: 17 | US FAERS | |
| 57 | Alopecia | FAERS: 15 | US FAERS | |
| 58 | Hyperthyroidism | FAERS: 15 | US FAERS | |
| 59 | Intestinal Perforation | FAERS: 15 | US FAERS | |
| 60 | Nephrotic Syndrome | FAERS: 15 | US FAERS | |
| 61 | Somnolence | FAERS: 15 | US FAERS | |
| 62 | Erythema | FAERS: 14 | US FAERS | |
| 63 | Infection | FAERS: 14 | US FAERS | |
| 64 | Musculoskeletal Pain | FAERS: 14 | US FAERS | |
| 65 | Portal Vein Thrombosis | FAERS: 14 | US FAERS | |
| 66 | Skin Ulcer | FAERS: 14 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 67 | Atrial Fibrillation | FAERS: 12 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 68 | Blood pressure fluctuation | FAERS: 12 | US FAERS | |
| 69 | Gastrointestinal perforation | FAERS: 12 | US FAERS | |
| 70 | Liver carcinoma ruptured | FAERS: 12 | US FAERS | |
| 71 | Nasopharyngitis | FAERS: 12 | US FAERS | |
| 72 | Blood sodium decreased | FAERS: 11 | US FAERS | |
| 73 | Pancytopenia | FAERS: 11 | US FAERS | |
| 74 | Tracheal fistula | FAERS: 11 | US FAERS | |
| 75 | Tremor | FAERS: 11 | US FAERS | |
| 76 | Blood potassium decreased | FAERS: 10 | US FAERS | |
| 77 | Drug ineffective | FAERS: 10 | US FAERS | |
| 78 | Dyspepsia | FAERS: 10 | US FAERS | |
| 79 | Abscess | FAERS: 9 | US FAERS | |
| 80 | Altered state of consciousness | FAERS: 9 | US FAERS | |
| 81 | Blood potassium increased | FAERS: 9 | US FAERS | |
| 82 | Chest discomfort | FAERS: 9 | US FAERS | |
| 83 | Ileus | FAERS: 9 | US FAERS | |
| 84 | Peritonitis | FAERS: 9 | US FAERS | |
| 85 | Acute myocardial infarction | FAERS: 8 | US FAERS | |
| 86 | Blood albumin decreased | FAERS: 8 | US FAERS | |
| 87 | Amnesia | FAERS: 7 | US FAERS | |
| 88 | Anxiety | FAERS: 7 | US FAERS | |
| 89 | Appendicitis | FAERS: 7 | US FAERS | |
| 90 | Ejection Fraction Decreased | FAERS: 7 | US FAERS | |
| 91 | Feeling Cold | FAERS: 7 | US FAERS | |
| 92 | Hyperkeratosis | FAERS: 7 | US FAERS | |
| 93 | Influenza | FAERS: 7 | US FAERS | |
| 94 | Joint swelling | FAERS: 7 | US FAERS | |
| 95 | Large intestine perforation | FAERS: 7 | US FAERS | |
| 96 | Mental status changes | FAERS: 7 | US FAERS | |
| 97 | Neutropenia | FAERS: 7 | US FAERS | |
| 98 | Neutrophil count decreased | FAERS: 7 | US FAERS | |
| 99 | Pruritus | FAERS: 7 | US FAERS | |
| 100 | Blood lactate dehydrogenase increased | FAERS: 6 | US FAERS | |
| 101 | Delirium | FAERS: 6 | US FAERS | |
| 102 | Disseminated Intravascular Coagulation | FAERS: 6 | US FAERS | |
| 103 | Enterocolitis | FAERS: 6 | US FAERS | |
| 104 | Flatulence | FAERS: 6 | US FAERS | |
| 105 | Memory impairment | FAERS: 6 | US FAERS | |
| 106 | Protein urine present | FAERS: 6 | US FAERS | |
| 107 | Respiratory Failure | FAERS: 6 | US FAERS | |
| 108 | Syncope | FAERS: 6 | US FAERS | |
| 109 | Thyroglobulin increased | FAERS: 6 | US FAERS | |
| 110 | Thyroiditis | FAERS: 6 | US FAERS | |
| 111 | Aphonia | FAERS: 5 | US FAERS | |
| 112 | Arthritis | FAERS: 5 | US FAERS | |
| 113 | Asphyxia | FAERS: 5 | US FAERS | |
| 114 | Biliary Fistula | FAERS: 5 | US FAERS | |
| 115 | Blood glucose decreased | FAERS: 5 | US FAERS | |
| 116 | Blood glucose increased | FAERS: 5 | US FAERS | |
| 117 | Blood magnesium decreased | FAERS: 5 | US FAERS | |
| 118 | Blood urine present | FAERS: 5 | US FAERS | |
| 119 | Cellulitis | FAERS: 5 | US FAERS | |
| 120 | Chills | FAERS: 5 | US FAERS | |
| 121 | Cold sweat | FAERS: 5 | US FAERS | |
| 122 | Cystitis | FAERS: 5 | US FAERS | |
| 123 | Disorientation | FAERS: 5 | US FAERS | |
| 124 | Dysuria | FAERS: 5 | US FAERS | |
| 125 | Electrolyte imbalance | FAERS: 5 | US FAERS | |
| 126 | Gastric ulcer | FAERS: 5 | US FAERS | |
| 127 | Gingivitis | FAERS: 5 | US FAERS | |
| 128 | Lung Abscess | FAERS: 5 | US FAERS | |
| 129 | Pneumatosis intestinalis | FAERS: 5 | US FAERS | |
| 130 | Septic Shock | FAERS: 5 | US FAERS | |
| 131 | Vertigo | FAERS: 5 | US FAERS | |
| 132 | Acne | FAERS: 4 | US FAERS | |
| 133 | Angina Pectoris | FAERS: 4 | US FAERS | |
| 134 | Aphasia | FAERS: 4 | US FAERS | |
| 135 | Blood urea increased | FAERS: 4 | US FAERS | |
| 136 | Cancer Pain | FAERS: 4 | US FAERS | |
| 137 | Colitis | FAERS: 4 | US FAERS | |
| 138 | Creatinine renal clearance decreased | FAERS: 4 | US FAERS | |
| 139 | Depressed Level of Consciousness | FAERS: 4 | US FAERS | |
| 140 | Feeling abnormal | FAERS: 4 | US FAERS | |
| 141 | Gait inability | FAERS: 4 | US FAERS | |
| 142 | Gastritis | FAERS: 4 | US FAERS | |
| 143 | General physical health deterioration | FAERS: 4 | US FAERS | |
| 144 | Hepatitis | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 145 | Hypersomnia | FAERS: 4 | US FAERS | |
| 146 | Hypertensive crisis | FAERS: 4 | US FAERS | |
| 147 | Hypophagia | FAERS: 4 | US FAERS | |
| 148 | Infectious pleural effusion | FAERS: 4 | US FAERS | |
| 149 | Leukoencephalopathy | FAERS: 4 | US FAERS | |
| 150 | Liver Abscess | FAERS: 4 | US FAERS | |
| 151 | Nervousness | FAERS: 4 | US FAERS | |
| 152 | Pericardial effusion | FAERS: 4 | US FAERS | |
| 153 | Product use issue | FAERS: 4 | US FAERS | |
| 154 | Sudden death | FAERS: 4 | US FAERS | |
| 155 | Throat irritation | FAERS: 4 | US FAERS | |
| 156 | Thrombosis | FAERS: 4 | US FAERS | |
| 157 | Tongue discomfort | FAERS: 4 | US FAERS | |
| 158 | Tooth Infection | FAERS: 4 | US FAERS | |
| 159 | Urticaria | FAERS: 4 | US FAERS | |
| 160 | Wound Infection | FAERS: 4 | US FAERS | |
| 161 | Accidental underdose | FAERS: 3 | US FAERS | |
| 162 | Atrial thrombosis | FAERS: 3 | US FAERS | |
| 163 | Blood count abnormal | FAERS: 3 | US FAERS | |
| 164 | Bradycardia | FAERS: 3 | US FAERS | |
| 165 | Bronchial Fistula | FAERS: 3 | US FAERS | |
| 166 | Bronchitis | FAERS: 3 | US FAERS | |
| 167 | Cardiac Tamponade | FAERS: 3 | US FAERS | |
| 168 | Carotid artery perforation | FAERS: 3 | US FAERS | |
| 169 | Cerebellar infarction | FAERS: 3 | US FAERS | |
| 170 | Cholecystitis infective | FAERS: 3 | US FAERS | |
| 171 | Coronary Artery Disease | FAERS: 3 | US FAERS | |
| 172 | Disease Progression | FAERS: 3 | US FAERS | |
| 173 | Diverticular perforation | FAERS: 3 | US FAERS | |
| 174 | Drug dose omission | FAERS: 3 | US FAERS | |
| 175 | Erythema Multiforme | FAERS: 3 | US FAERS | |
| 176 | Eye pain | FAERS: 3 | US FAERS | |
| 177 | Facial Pain | FAERS: 3 | US FAERS | |
| 178 | Gastroenteritis | FAERS: 3 | US FAERS | |
| 179 | Hypoxia | FAERS: 3 | US FAERS | |
| 180 | Intestinal Obstruction | FAERS: 3 | US FAERS | |
| 181 | Loose tooth | FAERS: 3 | US FAERS | |
| 182 | Loss of personal independence in daily activities | FAERS: 3 | US FAERS | |
| 183 | Malnutrition | FAERS: 3 | US FAERS | |
| 184 | Neoplasm swelling | FAERS: 3 | US FAERS | |
| 185 | Nephrolithiasis | FAERS: 3 | US FAERS | |
| 186 | Night sweats | FAERS: 3 | US FAERS | |
| 187 | Oral candidiasis | FAERS: 3 | US FAERS | |
| 188 | Periodontitis | FAERS: 3 | US FAERS | |
| 189 | Pleurisy | FAERS: 3 | US FAERS | |
| 190 | Productive Cough | FAERS: 3 | US FAERS | |
| 191 | Prothrombin level decreased | FAERS: 3 | US FAERS | |
| 192 | Pulmonary Fibrosis | FAERS: 3 | US FAERS | |
| 193 | Skin lesion | FAERS: 3 | US FAERS | |
| 194 | Stoma Site Infection | FAERS: 3 | US FAERS | |
| 195 | Stoma site pain | FAERS: 3 | US FAERS | |
| 196 | Swelling | FAERS: 3 | US FAERS | |
| 197 | Transaminases increased | FAERS: 3 | US FAERS | |
| 198 | Trismus | FAERS: 3 | US FAERS | |
| 199 | Trousseau's syndrome | FAERS: 3 | US FAERS | |
| 200 | Ulcer | FAERS: 3 | US FAERS | |
| 201 | Urinary Incontinence | FAERS: 3 | US FAERS | |
| 202 | Visual Impairment | FAERS: 3 | US FAERS | |
| 203 | Acute Coronary Syndrome | FAERS: 2 | US FAERS | |
| 204 | Ageusia | FAERS: 2 | US FAERS | |
| 205 | Agitation | FAERS: 2 | US FAERS | |
| 206 | Arterial thrombosis | FAERS: 2 | US FAERS | |
| 207 | Atrioventricular Block | FAERS: 2 | US FAERS | |
| 208 | Blood albumin increased | FAERS: 2 | US FAERS | |
| 209 | Blood cholesterol increased | FAERS: 2 | US FAERS | |
| 210 | Blood iron decreased | FAERS: 2 | US FAERS | |
| 211 | Blood sodium increased | FAERS: 2 | US FAERS | |
| 212 | Burning sensation | FAERS: 2 | US FAERS | |
| 213 | Cataract | FAERS: 2 | US FAERS | |
| 214 | Chromaturia | FAERS: 2 | US FAERS | |
| 215 | Compression fracture | FAERS: 2 | US FAERS | |
| 216 | Conjunctivitis | FAERS: 2 | US FAERS | |
| 217 | Deep Vein Thrombosis | FAERS: 2 | US FAERS | |
| 218 | Diabetes Mellitus | FAERS: 2 | US FAERS | |
| 219 | Diplopia | FAERS: 2 | US FAERS | |
| 220 | Discomfort | FAERS: 2 | US FAERS | |
| 221 | Dysarthria | FAERS: 2 | US FAERS | |
| 222 | Embolism | FAERS: 2 | US FAERS | |
| 223 | Enterocutaneous Fistula | FAERS: 2 | US FAERS | |
| 224 | Epilepsy | FAERS: 2 | US FAERS | |
| 225 | Escherichia urinary tract infection | FAERS: 2 | US FAERS | |
| 226 | Exfoliative rash | FAERS: 2 | US FAERS | |
| 227 | Eye Infection | FAERS: 2 | US FAERS | |
| 228 | Febrile Neutropenia | FAERS: 2 | US FAERS | |
| 229 | Fibromyalgia | FAERS: 2 | US FAERS | |
| 230 | Flank Pain | FAERS: 2 | US FAERS | |
| 231 | Fracture | FAERS: 2 | US FAERS | |
| 232 | Gastric infection | FAERS: 2 | US FAERS | |
| 233 | Gastrointestinal inflammation | FAERS: 2 | US FAERS | |
| 234 | Glossitis | FAERS: 2 | US FAERS | |
| 235 | Hernia | FAERS: 2 | US FAERS | |
| 236 | Hypersensitivity | FAERS: 2 | US FAERS | |
| 237 | Inappropriate schedule of product administration | FAERS: 2 | US FAERS | |
| 238 | Intra-abdominal fluid collection | FAERS: 2 | US FAERS | |
| 239 | Intracranial Aneurysm | FAERS: 2 | US FAERS | |
| 240 | Joint stiffness | FAERS: 2 | US FAERS | |
| 241 | Lethargy | FAERS: 2 | US FAERS | |
| 242 | Limb injury | FAERS: 2 | US FAERS | |
| 243 | Liver function test decreased | FAERS: 2 | US FAERS | |
| 244 | Microalbuminuria | FAERS: 2 | US FAERS | |
| 245 | Musculoskeletal chest pain | FAERS: 2 | US FAERS | |
| 246 | Musculoskeletal stiffness | FAERS: 2 | US FAERS | |
| 247 | Nail Infection | FAERS: 2 | US FAERS | |
| 248 | Necrosis | FAERS: 2 | US FAERS | |
| 249 | Oral mucosal eruption | FAERS: 2 | US FAERS | |
| 250 | Osteogenesis Imperfecta | FAERS: 2 | US FAERS | |
| 251 | Osteolysis | FAERS: 2 | US FAERS | |
| 252 | Osteomyelitis | FAERS: 2 | US FAERS | |
| 253 | Osteonecrosis of Jaw | FAERS: 2 | US FAERS | |
| 254 | Pain of skin | FAERS: 2 | US FAERS | |
| 255 | Paraplegia | FAERS: 2 | US FAERS | |
| 256 | Pathological fracture | FAERS: 2 | US FAERS | |
| 257 | Pharyngeal fistula | FAERS: 2 | US FAERS | |
| 258 | Primary Adrenal Insufficiency | FAERS: 2 | US FAERS | |
| 259 | Protein total increased | FAERS: 2 | US FAERS | |
| 260 | Pulmonary artery thrombosis | FAERS: 2 | US FAERS | |
| 261 | Pyelonephritis | FAERS: 2 | US FAERS | |
| 262 | Retching | FAERS: 2 | US FAERS | |
| 263 | Rhinitis | FAERS: 2 | US FAERS | |
| 264 | Skin reaction | FAERS: 2 | US FAERS | |
| 265 | Sphincter of Oddi Dysfunction | FAERS: 2 | US FAERS | |
| 266 | Subcutaneous Abscess | FAERS: 2 | US FAERS | |
| 267 | Superior Vena Cava Syndrome | FAERS: 2 | US FAERS | |
| 268 | Supraventricular tachycardia | FAERS: 2 | US FAERS | |
| 269 | Tachycardia | FAERS: 2 | US FAERS | |
| 270 | Tendon discomfort | FAERS: 2 | US FAERS | |
| 271 | Thyroid hormones decreased | FAERS: 2 | US FAERS | |
| 272 | Tooth Loss | FAERS: 2 | US FAERS | |
| 273 | Upper airway obstruction | FAERS: 2 | US FAERS | |
| 274 | Urinary Retention | FAERS: 2 | US FAERS | |
| 275 | Vertebral Artery Dissection | FAERS: 2 | US FAERS | |
| 276 | Wound dehiscence | FAERS: 2 | US FAERS | |
| 277 | Zinc deficiency | FAERS: 2 | US FAERS | |
| 278 | furuncle | FAERS: 2 | US FAERS | |
| 279 | Abdominal Abscess | FAERS: 1 | US FAERS | |
| 280 | Abdominal Infection | FAERS: 1 | US FAERS | |
| 281 | Accidental overdose | FAERS: 1 | US FAERS | |
| 282 | Acute prerenal failure | FAERS: 1 | US FAERS | |
| 283 | Acute respiratory failure | FAERS: 1 | US FAERS | |
| 284 | Allergic sinusitis | FAERS: 1 | US FAERS | |
| 285 | Amylase increased | FAERS: 1 | US FAERS | |
| 286 | Anal abscess | FAERS: 1 | US FAERS | |
| 287 | Anuria | FAERS: 1 | US FAERS | |
| 288 | Aortic Aneurysm | FAERS: 1 | US FAERS | |
| 289 | Aspergilloma | FAERS: 1 | US FAERS | |
| 290 | Asterixis | FAERS: 1 | US FAERS | |
| 291 | Asthma | FAERS: 1 | US FAERS | |
| 292 | Bedridden | FAERS: 1 | US FAERS | |
| 293 | Benign Prostatic Hyperplasia | FAERS: 1 | US FAERS | |
| 294 | Bicytopenia | FAERS: 1 | US FAERS | |
| 295 | Biliary Colic | FAERS: 1 | US FAERS | |
| 296 | Biliary sepsis | FAERS: 1 | US FAERS | |
| 297 | Blindness | FAERS: 1 | US FAERS | |
| 298 | Blood calcium abnormal | FAERS: 1 | US FAERS | |
| 299 | Blood creatine increased | FAERS: 1 | US FAERS | |
| 300 | Blood creatine phosphokinase increased | FAERS: 1 | US FAERS | |
| 301 | Blood iron increased | FAERS: 1 | US FAERS | |
| 302 | Blood triglycerides increased | FAERS: 1 | US FAERS | |
| 303 | Body temperature fluctuation | FAERS: 1 | US FAERS | |
| 304 | Bone abscess | FAERS: 1 | US FAERS | |
| 305 | Bowel movement irregularity | FAERS: 1 | US FAERS | |
| 306 | Brain Abscess | FAERS: 1 | US FAERS | |
| 307 | Bronchial Obstruction | FAERS: 1 | US FAERS | |
| 308 | Bronchiectasis | FAERS: 1 | US FAERS | |
| 309 | Bronchopleural Fistula | FAERS: 1 | US FAERS | |
| 310 | Cachexia | FAERS: 1 | US FAERS | |
| 311 | Candida sepsis | FAERS: 1 | US FAERS | |
| 312 | Cardiac dysfunction | FAERS: 1 | US FAERS | |
| 313 | Carotid artery occlusion | FAERS: 1 | US FAERS | |
| 314 | Cavernous Sinus Thrombosis | FAERS: 1 | US FAERS | |
| 315 | Cerebral Thrombosis | FAERS: 1 | US FAERS | |
| 316 | Cheilitis | FAERS: 1 | US FAERS | |
| 317 | Choking sensation | FAERS: 1 | US FAERS | |
| 318 | Cholelithiasis | FAERS: 1 | US FAERS | |
| 319 | Cytopenia | FAERS: 1 | US FAERS | |
| 320 | Deafness | FAERS: 1 | US FAERS | |
| 321 | Dermatitis acneiform | FAERS: 1 | US FAERS | |
| 322 | Dermatitis | FAERS: 1 | US FAERS | |
| 323 | Device related infection | FAERS: 1 | US FAERS | |
| 324 | Diaphragmalgia | FAERS: 1 | US FAERS | |
| 325 | Disability | FAERS: 1 | US FAERS | |
| 326 | Diverticulitis | FAERS: 1 | US FAERS | |
| 327 | Drowning | FAERS: 1 | US FAERS | |
| 328 | Duodenal Ulcer | FAERS: 1 | US FAERS | |
| 329 | Duodenal perforation | FAERS: 1 | US FAERS | |
| 330 | Duodenitis | FAERS: 1 | US FAERS | |
| 331 | Endophthalmitis | FAERS: 1 | US FAERS | |
| 332 | Enteritis | FAERS: 1 | US FAERS | |
| 333 | Epileptic encephalopathy | FAERS: 1 | US FAERS | |
| 334 | Escherichia sepsis | FAERS: 1 | US FAERS | |
| 335 | Facial paralysis | FAERS: 1 | US FAERS | |
| 336 | Failure to Thrive | FAERS: 1 | US FAERS | |
| 337 | Feeding tube user | FAERS: 1 | US FAERS | |
| 338 | Folliculitis | FAERS: 1 | US FAERS | |
| 339 | Fungal test positive | FAERS: 1 | US FAERS | |
| 340 | Gangrene | FAERS: 1 | US FAERS | |
| 341 | Gastroenteritis norovirus | FAERS: 1 | US FAERS | |
| 342 | Gastrointestinal infection | FAERS: 1 | US FAERS | |
| 343 | Gastrointestinal ulcer perforation | FAERS: 1 | US FAERS | |
| 344 | Gastrointestinal ulcer | FAERS: 1 | US FAERS | |
| 345 | Gastrostomy | FAERS: 1 | US FAERS | |
| 346 | Gout | FAERS: 1 | US FAERS | |
| 347 | Granulocyte count decreased | FAERS: 1 | US FAERS | |
| 348 | Head discomfort | FAERS: 1 | US FAERS | |
| 349 | Heat illness | FAERS: 1 | US FAERS | |
| 350 | Hemiplegia | FAERS: 1 | US FAERS | |
| 351 | Hepatic Infection | FAERS: 1 | US FAERS | |
| 352 | Hepatic Vein Thrombosis | FAERS: 1 | US FAERS | |
| 353 | Hepatic hydrothorax | FAERS: 1 | US FAERS | |
| 354 | Hepatorenal Syndrome | FAERS: 1 | US FAERS | |
| 355 | Hepatotoxicity | FAERS: 1 | US FAERS | |
| 356 | Hunger | FAERS: 1 | US FAERS | |
| 357 | Hypertensive Encephalopathy | FAERS: 1 | US FAERS | |
| 358 | Hypogeusia | FAERS: 1 | US FAERS | |
| 359 | Hypoglossal nerve paralysis | FAERS: 1 | US FAERS | |
| 360 | Incision site impaired healing | FAERS: 1 | US FAERS | |
| 361 | Incoherent | FAERS: 1 | US FAERS | |
| 362 | Incontinence | FAERS: 1 | US FAERS | |
| 363 | Incorrect dose administered | FAERS: 1 | US FAERS | |
| 364 | Incorrect drug administration duration | FAERS: 1 | US FAERS | |
| 365 | Increased tendency to bruise | FAERS: 1 | US FAERS | |
| 366 | Increased viscosity of upper respiratory secretion | FAERS: 1 | US FAERS | |
| 367 | Inflammation | FAERS: 1 | US FAERS | |
| 368 | Irritable Bowel Syndrome | FAERS: 1 | US FAERS | |
| 369 | Joint injury | FAERS: 1 | US FAERS | |
| 370 | Lactose Intolerance | FAERS: 1 | US FAERS | |
| 371 | Leukopenia | FAERS: 1 | US FAERS | |
| 372 | Lipase increased | FAERS: 1 | US FAERS | |
| 373 | Lower respiratory tract infection | FAERS: 1 | US FAERS | |
| 374 | Lyme Disease | FAERS: 1 | US FAERS | |
| 375 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 376 | Lymphangiosis carcinomatosa | FAERS: 1 | US FAERS | |
| 377 | MYELODYSPLASTIC SYNDROME | FAERS: 1 | US FAERS | |
| 378 | Macule | FAERS: 1 | US FAERS | |
| 379 | Mechanical ileus | FAERS: 1 | US FAERS | |
| 380 | Mediastinitis | FAERS: 1 | US FAERS | |
| 381 | Mental impairment | FAERS: 1 | US FAERS | |
| 382 | Metrorrhagia | FAERS: 1 | US FAERS | |
| 383 | Miliaria | FAERS: 1 | US FAERS | |
| 384 | Mouth swelling | FAERS: 1 | US FAERS | |
| 385 | Myocardial necrosis marker increased | FAERS: 1 | US FAERS | |
| 386 | Myocarditis | FAERS: 1 | US FAERS | |
| 387 | Neuralgia | FAERS: 1 | US FAERS | |
| 388 | Non-cardiac chest pain | FAERS: 1 | US FAERS | |
| 389 | Nutritional condition abnormal | FAERS: 1 | US FAERS | |
| 390 | Oropharyngeal discomfort | FAERS: 1 | US FAERS | |
| 391 | Pain management | FAERS: 1 | US FAERS | |
| 392 | Pallor | FAERS: 1 | US FAERS | |
| 393 | Palpitations | FAERS: 1 | US FAERS | |
| 394 | Pancreatic carcinoma | FAERS: 1 | US FAERS | |
| 395 | Paranoia | FAERS: 1 | US FAERS | |
| 396 | Parophthalmia | FAERS: 1 | US FAERS | |
| 397 | Parotitis | FAERS: 1 | US FAERS | |
| 398 | Performance status decreased | FAERS: 1 | US FAERS | |
| 399 | Peritonsillitis | FAERS: 1 | US FAERS | |
| 400 | Pharyngeal swelling | FAERS: 1 | US FAERS | |
| 401 | Pneumonitis | FAERS: 1 | US FAERS | |
| 402 | Post procedural fever | FAERS: 1 | US FAERS | |
| 403 | Postoperative abscess | FAERS: 1 | US FAERS | |
| 404 | Procedural hypotension | FAERS: 1 | US FAERS | |
| 405 | Product packaging difficult to open | FAERS: 1 | US FAERS | |
| 406 | Product use complaint | FAERS: 1 | US FAERS | |
| 407 | Protein total abnormal | FAERS: 1 | US FAERS | |
| 408 | Pulmonary Hypertension | FAERS: 1 | US FAERS | |
| 409 | Pulmonary sepsis | FAERS: 1 | US FAERS | |
| 410 | Purpura | FAERS: 1 | US FAERS | |
| 411 | Quality of life decreased | FAERS: 1 | US FAERS | |
| 412 | Recall phenomenon | FAERS: 1 | US FAERS | |
| 413 | Rectal discharge | FAERS: 1 | US FAERS | |
| 414 | Renal abscess | FAERS: 1 | US FAERS | |
| 415 | Renal pain | FAERS: 1 | US FAERS | |
| 416 | Respiratory distress | FAERS: 1 | US FAERS | |
| 417 | Retroperitoneal fibrosis | FAERS: 1 | US FAERS | |
| 418 | Rhabdomyolysis | FAERS: 1 | US FAERS | |
| 419 | Saliva altered | FAERS: 1 | US FAERS | |
| 420 | Sarcoidosis | FAERS: 1 | US FAERS | |
| 421 | Shunt thrombosis | FAERS: 1 | US FAERS | |
| 422 | Sinus Tachycardia | FAERS: 1 | US FAERS | |
| 423 | Sinus bradycardia | FAERS: 1 | US FAERS | |
| 424 | Sinusitis | FAERS: 1 | US FAERS | |
| 425 | Skin irritation | FAERS: 1 | US FAERS | |
| 426 | Sneezing | FAERS: 1 | US FAERS | |
| 427 | Squamous cell carcinoma | FAERS: 1 | US FAERS | |
| 428 | Stevens-Johnson Syndrome | FAERS: 1 | US FAERS | |
| 429 | Stridor | FAERS: 1 | US FAERS | |
| 430 | Stubbornness | FAERS: 1 | US FAERS | |
| 431 | Subileus | FAERS: 1 | US FAERS | |
| 432 | Sudden Cardiac Death | FAERS: 1 | US FAERS | |
| 433 | Suicide attempt | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 434 | Sunburn | FAERS: 1 | US FAERS | |
| 435 | Superinfection | FAERS: 1 | US FAERS | |
| 436 | Swelling of eyelid | FAERS: 1 | US FAERS | |
| 437 | Tachyarrhythmia | FAERS: 1 | US FAERS | |
| 438 | Therapy change | FAERS: 1 | US FAERS | |
| 439 | Thyroglobulin decreased | FAERS: 1 | US FAERS | |
| 440 | Thyroid hormones increased | FAERS: 1 | US FAERS | |
| 441 | Tongue blistering | FAERS: 1 | US FAERS | |
| 442 | Tongue erythema | FAERS: 1 | US FAERS | |
| 443 | Toxicity to various agents | FAERS: 1 | US FAERS | |
| 444 | Tracheal Stenosis | FAERS: 1 | US FAERS | |
| 445 | Vascular pseudoaneurysm ruptured | FAERS: 1 | US FAERS | |
| 446 | Vascular rupture | FAERS: 1 | US FAERS | |
| 447 | Vocal Cord Paralysis | FAERS: 1 | US FAERS | |
| 448 | Wheezing | FAERS: 1 | US FAERS | |
| 449 | colonoscopy | FAERS: 1 | US FAERS | |
| 450 | Neoplasms, Experimental | 21225632 | CTD |
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