MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Rift Valley Fever

(UMLS:C0035613)

Definition:: An acute infection caused by the RIFT VALLEY FEVER VIRUS, an RNA arthropod-borne virus, affecting domestic animals and humans. In animals, symptoms include HEPATITIS; abortion (ABORTION, VETERINARY); and DEATH. In humans, symptoms range from those of a flu-like disease to hemorrhagic fever, ENCEPHALITIS, or BLINDNESS.
UMLS ID:: C0035613
MeSH ID:: D012295

Classification 1:

Name:

Virus Diseases
MeSH Tree Number(s):: C02.081.810|C02.407.810|C02.782.147.810|C02.782.417.762

Classification 2:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.552.380.315.430.812

Classification 3:

Name:

Animal Diseases
MeSH Tree Number(s):: C22.467.435.812

Synonym(s)

Rift Valley Fever

Enzootic hepatitis

RVF

RVF - Rift valley fever

Rift Valley fever

Rift Valley; fever

Rift valley fever

Viral hemorrhagic fever, Rift valley

Zinga fever

10.

fever; Rift Valley

11.

rift valley fever

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Everolimus	FAERS: 1		US FAERS
2	Fentanyl	FAERS: 1		US FAERS
3	Ribavirin	FAERS: 1	2546248	CTD US FAERS
4	Triumeq	FAERS: 1		US FAERS
5	Valsartan	FAERS: 1		US FAERS
6	isavuconazole	FAERS: 1		US FAERS
7	Cisapride			OFFSIDES
8	Medroxyprogesterone Acetate			OFFSIDES
9	Medroxyprogesterone			OFFSIDES
10	rofecoxib			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Hemorrhagic Fever, Crimean	50.8%
2	Dengue Fever	46.5%
3	Yellow Fever	46.5%
4	Phlebotomus Fever	40.8%
5	Hemorrhagic Fever with Renal Syndrome	38.6%
6	Hemorrhagic Fever, American	37.1%
7	Lassa Fever	37.1%
8	Hepatitis E	34.2%
9	West Nile Fever	31.1%
10	Zika Virus Infection	30.4%
11	Hepatitis C	28%
12	Hepatitis, Viral, Human	26.6%
13	Murine Acquired Immunodeficiency Syndrome	26.6%
14	Warts	25.8%
15	Orthomyxoviridae Infections	25.3%
16	Picornaviridae Infections	25.3%
17	Reoviridae Infections	25.3%
18	Retroviridae Infections	25.3%
19	Subacute Sclerosing Panencephalitis	25.1%
20	Hepatitis A	24.9%
21	Rift Valley Fever	24.8%
22	Condylomata Acuminata	23%
23	Acquired Immunodeficiency Syndrome	22.8%
24	AIDS related complex	22.8%
25	Simian Acquired Immunodeficiency Syndrome	22.5%
26	Hepatitis B	22%
27	Hepatitis C, Chronic	21.8%
28	Leukoencephalopathy, Progressive Multifocal	21.5%
29	Epstein-Barr Virus Infections	20.4%
30	Pseudorabies	20%
31	Herpangina	20%
32	Foot-and-Mouth Disease	19.9%
33	Viremia	18.9%
34	Epidermodysplasia Verruciformis	18.7%
35	HIV Infections	18%
36	Molluscum Contagiosum	18%
37	Hepatitis B, Chronic	17.8%
38	Opportunistic Infections	17.4%
39	Enterovirus Infections	17.3%
40	Flavivirus Infections	17.3%
41	Paramyxoviridae Infections	17.3%
42	Cardiovirus Infections	17.3%
43	Rhabdoviridae Infections	17.3%
44	Pneumonia, Viral	16.8%
45	Erythema Infectiosum	16.2%
46	AIDS-Related Opportunistic Infections	16%
47	Arbovirus Infections	15.9%
48	Herpes Zoster Ophthalmicus	15.7%
49	Chronic Fatigue Syndrome	15.3%
50	Sexually Transmitted Diseases	15.3%
51	Common Cold	15.3%
52	Influenza	15.3%
53	Catarrh	15.3%
54	Keratitis, Herpetic	14.8%
55	Cytomegalovirus Retinitis	14.8%
56	HIV Seropositivity	14.8%
57	Exanthema Subitum	14.8%
58	Vesicular Stomatitis	14.5%
59	Porcine Reproductive and Respiratory Syndrome	14.4%
60	Herpesviridae Infections	13.6%
61	Polyomavirus Infections	13.6%
62	Coxsackievirus Infections	13.4%
63	Rubella	13.4%
64	Coronavirus Infections	13.4%
65	Nipah Virus Infection	13.4%
66	Hydrophobia	13.4%
67	Eczema Herpeticum	13.3%
68	Gastroenteritis, Transmissible, of Swine	12.7%
69	Hepatitis, Viral, Animal	12.3%
70	Genital Herpes	12.1%
71	HIV Wasting Syndrome	12.1%
72	AIDS Dementia Complex	12.1%
73	AIDS-Associated Nephropathy	12.1%
74	Herpes Labialis	12%
75	HTLV-I Infections	11.7%
76	Measles	11.5%
77	Pleurodynia, Epidemic	11.5%
78	Respiratory Syncytial Virus Infections	11.5%
79	HIV-Associated Lipodystrophy Syndrome	11%
80	Burkitt Lymphoma	10.8%
81	Superinfection	10.6%
82	Severe Acute Respiratory Syndrome	10.1%
83	Mumps	10%
84	Cytomegalovirus Infections	9.6%
85	Smallpox	9.6%
86	Varicella Zoster Virus Infection	9.6%
87	Poliomyelitis	9.4%
88	Hepatitis, Alcoholic	9.3%
89	Hepatitis, Chronic	8.4%
90	Chronic active hepatitis	8.4%
91	Chickenpox	7.7%
92	Liver neoplasms	6.8%
93	Bell Palsy	6.8%
94	Fatty Liver	6.6%
95	Portal Hypertension	6.6%
96	Liver Cirrhosis	6.6%
97	Focal Nodular Hyperplasia	6.6%
98	Hepatic Insufficiency	6.6%
99	Steatohepatitis	6.6%
100	Biliary cirrhosis	5.9%
101	Liver Diseases, Parasitic	5.9%
102	Hepatic Veno-Occlusive Disease	5.8%
103	Peliosis Hepatis	5.8%
104	Hepatopulmonary Syndrome	5.8%
105	Hepatomegaly	5.7%
106	Hepatic Vein Thrombosis	5.7%
107	Liver Abscess	5.7%
108	Budd-Chiari Syndrome	5.7%
109	Fatty Liver, Alcoholic	5.6%
110	Liver Cirrhosis, Alcoholic	5.6%
111	Infectious Mononucleosis	5.4%
112	Chemical and Drug Induced Liver Injury	5.2%
113	Hepatorenal Syndrome	5.1%
114	Bird Diseases	5%
115	Cat Diseases	5%
116	Cattle Diseases	5%
117	Dog Diseases	5%
118	Fish Diseases	5%
119	Horse Diseases	5%
120	Lameness, Animal	5%
121	Muscular Dystrophy, Animal	5%
122	Rodent Diseases	5%
123	Sheep Diseases	5%
124	Herpes Zoster Oticus	4.7%
125	Liver Abscess, Amebic	4.6%
126	Porphyrias, Hepatic	4.6%
127	Autoimmune hepatitis	4.4%
128	Parasitic Diseases, Animal	4.4%
129	Abortion, Veterinary	4.3%
130	Erysipelothrix infection	4.3%
131	Salmonella Infections, Animal	4.3%
132	Biliary Tract Diseases	4.2%
133	Gastrointestinal Diseases	4.2%
134	Pancreatic Diseases	4.2%
135	Esophageal and Gastric Varices	4.2%
136	Human anaplasmosis	3.8%
137	Digestive System Neoplasms	3.7%
138	Liver Failure	3.6%
139	Non-alcoholic Fatty Liver Disease	3.6%
140	Gastrointestinal Neoplasms	3.4%
141	Pancreatic Fistula	3.4%
142	Hepatocellular Adenoma	3.3%
143	Zollinger-Ellison syndrome	3.2%
144	Liver Cirrhosis, Experimental	3.2%
145	Peritoneal Neoplasms	3.1%
146	Strongyle Infections, Equine	3.1%
147	Liver Neoplasms, Experimental	3.1%
148	Monkey Diseases	2.9%
149	Poultry Diseases	2.9%
150	Fascioliasis	2.8%
151	Echinococcosis, Hepatic	2.8%
152	Chemical and Drug Induced Liver Injury, Chronic	2.8%
153	Pancreatic Neoplasm	2.8%
154	Zellweger Syndrome	2.8%
155	Reye Syndrome	2.8%
156	Mesenteric vascular insufficiency	2.7%
157	Esophageal Atresia	2.6%
158	Intestinal Atresia	2.6%
159	Mesenteric Vascular Occlusion	2.6%
160	Hepatolenticular Degeneration	2.6%
161	Intestinal Fistula	2.6%
162	Enterocutaneous Fistula	2.6%
163	Bile Duct Neoplasms	2.5%
164	gallbladder neoplasm	2.5%
165	Intestinal Neoplasms	2.5%
166	Stomach Neoplasms	2.5%
167	Variegate Porphyria	2.5%
168	Acute intermittent porphyria	2.5%
169	Porphyria Cutanea Tarda	2.5%
170	Choledochal Cyst	2.4%
171	Helminthiasis, Animal	2.3%
172	Protozoan Infections, Animal	2.3%
173	Esophageal Neoplasms	2.3%
174	Scrapie	2.3%
175	Bile Duct Diseases	2.2%
176	Cholelithiasis	2.2%
177	Chylous Ascites	2.2%
178	Esophageal Diseases	2.2%
179	Gastroenteritis	2.2%
180	Intestinal Diseases	2.2%
181	Pancreatic Insufficiency	2.2%
182	Pancreatitis	2.2%
183	Pneumoperitoneum	2.2%
184	Stomach Diseases	2.2%
185	Liver Failure, Acute	2.2%
186	End Stage Liver Disease	2.2%
187	Dysentery	2.1%
188	Enteritis	2.1%
189	Enterocolitis	2.1%
190	Esophagitis	2.1%
191	Gastritis	2.1%
192	Inflammatory Bowel Diseases	2.1%
193	Cholecystolithiasis	2.1%
194	Colorectal Neoplasms	2.1%
195	Pancreatic Cyst	1.9%
196	Anus, Imperforate	1.9%
197	Gastrointestinal Hemorrhage	1.9%
198	Hemoperitoneum	1.9%
199	Mesenteric Panniculitis	1.9%
200	Panniculitis, Peritoneal	1.9%
201	Peritonitis	1.9%
202	Peritoneal Fibrosis	1.9%
203	Encapsulating Peritoneal Sclerosis	1.9%
204	Anorectal Malformations	1.9%
205	Biliary Fistula	1.9%
206	Gastric Fistula	1.9%
207	Tuberculosis, Gastrointestinal	1.9%
208	Gastrointestinal Stromal Tumors	1.9%
209	Rectal Fistula	1.8%
210	Anal Fistula	1.8%
211	Furunculosis	1.8%
212	furuncle	1.8%
213	Cecal Neoplasms	1.8%
214	Duodenal Neoplasms	1.8%
215	Proctocolitis	1.8%
216	Colitis	1.7%
217	Duodenogastric Reflux	1.7%
218	Peptic Ulcer	1.7%
219	Proctitis	1.7%
220	Choledocholithiasis	1.7%
221	Hepatic Encephalopathy	1.7%
222	Duodenitis	1.7%
223	Ileitis	1.7%
224	Erosive Duodenitis	1.7%
225	Cystic Fibrosis	1.6%
226	Cryptosporidiosis	1.5%
227	Congenital Hyperinsulinism	1.5%
228	Appendicitis	1.5%
229	Massive Hepatic Necrosis	1.4%
230	Babesiosis	1.3%
231	Toxocariasis	1.3%
232	Dirofilariasis	1.3%
233	Carcinoma, Pancreatic Ductal	1.3%
234	Crohn Disease	1.3%
235	Duodenal Obstruction	1.3%
236	Enterocolitis, Neutropenic	1.3%
237	Necrotizing Enterocolitis	1.3%
238	Adenomatous Polyposis Coli	1.2%
239	Cecal Diseases	1.2%
240	Cholangitis	1.2%
241	Cholecystitis	1.2%
242	Cholestasis	1.2%
243	Colonic Diseases	1.2%
244	Common Bile Duct Diseases	1.2%
245	Esophageal Stenosis	1.2%
246	Ileal Diseases	1.2%
247	Intestinal Obstruction	1.2%
248	Intestinal Perforation	1.2%
249	Jejunal Diseases	1.2%
250	Pneumatosis Cystoides Intestinalis	1.2%
251	Rectal Diseases	1.2%
252	Gastric Dilatation	1.2%
253	Pancreatitis, Chronic	1.2%
254	Gastric outlet obstruction	1.2%
255	Cronkhite-Canada Syndrome	1.2%
256	Intestinal Polyposis	1.2%
257	Appendiceal Neoplasms	1.2%
258	Colonic Neoplasms	1.2%
259	Rectal Neoplasms	1.2%
260	Enterocolitis, Pseudomembranous	1.1%
261	pseudomembranous colitis	1.1%
262	Dysentery, Bacillary	1.1%
263	Pouchitis	1.1%
264	Anus Neoplasms	1.1%
265	Sigmoid Neoplasms	1.1%
266	Esophageal Perforation	1.1%
267	Intestinal Diseases, Parasitic	1.1%
268	Barrett Esophagus	1.1%
269	Deglutition Disorders	1.1%
270	Achlorhydria	1.1%
271	Pancreatic Pseudocyst	1.1%
272	Gastric Antral Vascular Ectasia	1.1%
273	Peptic Ulcer Hemorrhage	1%
274	Gastroparesis	1%
275	Pancreatitis, Alcoholic	1%
276	Duodenal Ulcer	1%
277	Peptic Ulcer Perforation	1%
278	Gastric ulcer	1%
279	Melena	0.9%
280	Colitis, Ischemic	0.9%
281	Hematemesis	0.9%
282	Nesidioblastosis	0.8%
283	insulinoma	0.8%
284	Gastrinoma	0.8%
285	Glucagonoma	0.8%
286	Vipoma	0.8%
287	Colonic Pseudo-Obstruction	0.7%
288	Cholestasis, Extrahepatic	0.7%
289	Biliary Dyskinesia	0.7%
290	Cholangitis, Sclerosing	0.7%
291	Colonic Diseases, Functional	0.7%
292	Esophageal motility disorders	0.7%
293	Fecal Incontinence	0.7%
294	Fecal Impaction	0.7%
295	Intussusception	0.7%
296	Mallory-Weiss Syndrome	0.7%
297	Megacolon	0.7%
298	Pyloric Stenosis	0.7%
299	Acalculous Cholecystitis	0.7%
300	Ileus	0.7%
301	Meconium ileus	0.7%
302	Hemorrhoids	0.6%
303	Afferent Loop Syndrome	0.6%
304	Celiac Disease	0.6%
305	Short Bowel Syndrome	0.6%
306	Sprue, Tropical	0.6%
307	Steatorrhea	0.6%
308	Rectocele	0.6%
309	Sprue	0.6%
310	Diverticulitis	0.6%
311	Dumping Syndrome	0.6%
312	Rectal Prolapse	0.6%
313	Giardiasis	0.6%
314	Diverticulum	0.6%
315	Diverticulosis	0.6%
316	Peutz-Jeghers Syndrome	0.5%
317	Lactose Intolerance	0.5%
318	Esophageal Achalasia	0.5%
319	Anal Fissure	0.5%
320	Intestinal Pseudo-Obstruction	0.5%
321	Irritable Bowel Syndrome	0.5%
322	Superior Mesenteric Artery Syndrome	0.5%
323	Emphysematous Cholecystitis	0.5%
324	Neurogenic Bowel	0.5%
325	Sphincter of Oddi Dysfunction	0.5%
326	Anal Ulcer	0.5%
327	Pruritus Ani	0.4%
328	Laryngopharyngeal Reflux	0.3%
329	CREST Syndrome	0.3%

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