MetaADEDB 2.0 @ LMMD
Toremifene
(XFCLJVABOIYOMF-QPLCGJKRSA-N)
Structure
SMILES
ClCC/C(=C(\c1ccccc1)/c1ccc(cc1)OCCN(C)C)/c1ccccc1
Type(s)
Approved; Investigational
ATC code(s)
L02BA02
Molecular Formula:
C26H28ClNO
Molecular Weight:
405.960
Log P:
6.2150
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
12.47
CAS Number(s):
89778-26-7; 89778-29-0
Synonym(s)
1.
Toremifene
2.
FC-1157a
3.
Fareston
4.
Toremifene Citrate
5.
Toremifene Citrate (1:1)
6.
Toremifene, (E)-Isomer
7.
Citrate, Toremifene
8.
FC 1157a
9.
FC1157a
External Link(s)
MeSHD017312
PubChem Compound3005573
BindingDB50393326
58492
ChEBI9635
CHEMBLCHEMBL1655
DrugBankDB00539
DrugCentral2709
IUPHAR/BPS Guide to PHARMACOLOGY4325
KEGGcpd:C08166
dr:D08620
Therapeutic Target DatabaseD04VFJ
ZINC12404516
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Endometrial HyperplasiaFAERS: 2SIDER
US FAERS
2Endometrial hypertrophyFAERS: 2OFFSIDES
SIDER
US FAERS
3Breast cancer recurrentFAERS: 1US FAERS
4Cerebrovascular accidentFAERS: 1US FAERS
5Drug administered to patient of inappropriate ageFAERS: 1US FAERS
6Endometrial sarcomaFAERS: 1US FAERS
7InfectionFAERS: 1US FAERS
8Malignant neoplasm progressionFAERS: 1OFFSIDES
US FAERS
9Pelvic PainFAERS: 1US FAERS
10Product dose omissionFAERS: 1US FAERS
11Product use in unapproved indicationFAERS: 1US FAERS
12Rectosigmoid cancerFAERS: 1US FAERS
13Abdominal PainOFFSIDES
14Abdominal discomfortOFFSIDES
15Abnormal visionSIDER
16AbscessOFFSIDES
17Acute Coronary SyndromeSIDER
18AdenocarcinomaOFFSIDES
19AlopeciaSIDER
20Angina PectorisSIDER
21AnorexiaSIDER
22AppendectomyOFFSIDES
23ArthritisOFFSIDES
SIDER
24Aspiration PneumoniaOFFSIDES
25AstheniaSIDER
26AtaxiaSIDER
27Back PainSIDER
28Basal cell carcinomaOFFSIDES
29Blast cell count decreasedOFFSIDES
30Blood GlucoseOFFSIDES
31Blood albumin decreasedOFFSIDES
32Blood alkaline phosphatase increasedOFFSIDES
33Blood creatinine decreasedOFFSIDES
34Blood lactate dehydrogenase increasedOFFSIDES
35Blood potassium decreasedOFFSIDES
36Blood urea increasedOFFSIDES
37Blurred visionOFFSIDES
38Bone density decreasedOFFSIDES
39Bone trimmingOFFSIDES
40BursitisOFFSIDES
41CataractOFFSIDES
SIDER
42Cell marker increasedOFFSIDES
43CheilitisOFFSIDES
44Chest PainSIDER
45ChillsSIDER
46Congenital tricuspid valve incompetenceOFFSIDES
47ConstipationSIDER
48Corneal InfectionOFFSIDES
49Corneal OpacitySIDER
50CystSIDER
51DebridementOFFSIDES
52Deep Vein ThrombosisSIDER
53DermatitisSIDER
54DiplopiaSIDER
55Disseminated Intravascular CoagulationOFFSIDES
56DiverticulumOFFSIDES
57DizzinessSIDER
58DysgeusiaOFFSIDES
59Ear and labyrinth disordersSIDER
60EmbolismSIDER
61Enamel anomalyOFFSIDES
62Endometrial cancer stage IIIOFFSIDES
63Erosive gastritisOFFSIDES
64Ethmoid sinus surgeryOFFSIDES
65FatigueSIDER
66Fatty LiverOFFSIDES
67Female Urogenital Diseases16709447CTD
68FibromyalgiaOFFSIDES
69Flank PainOFFSIDES
70Gamma-Glutamyltransferase IncreasedOFFSIDES
71Gingival blisterOFFSIDES
72GlaucomaOFFSIDES
SIDER
73GoiterOFFSIDES
74HeadacheSIDER
75HepatitisOFFSIDES
76HordeolumOFFSIDES
77HydronephrosisOFFSIDES
78Intervertebral Disc DegenerationOFFSIDES
79Jaw lesion excisionOFFSIDES
80KeratopathySIDER
81Lactose IntoleranceOFFSIDES
82Left Ventricular HypertrophyOFFSIDES
83LethargySIDER
84Leukopenia neonatalOFFSIDES
85LeukopeniaSIDER
86LeukorrheaSIDER
87Liver neoplasms7586193
8402624
8972233		CTD
88LymphedemaOFFSIDES
89Lysosomal Storage Diseases28551711CTD
90Malignant melanoma in situOFFSIDES
91MalnutritionSIDER
92Maxillofacial operationOFFSIDES
93Mood swingsSIDER
94Muscle necrosisOFFSIDES
95Musculoskeletal chest painOFFSIDES
96Musculoskeletal stiffnessSIDER
97Myocardial InfarctionSIDER
98NasopharyngitisOFFSIDES
99NauseaSIDER
100Nephrogenic Fibrosing DermopathyOFFSIDES
101Nephrotic SyndromeOFFSIDES
102NocturiaOFFSIDES
103Non-alcoholic Fatty Liver Disease10348023
11078796		CTD
104Oral Cavity FistulaOFFSIDES
105Oroantral FistulaOFFSIDES
106OsteolysisOFFSIDES
107OsteomyelitisOFFSIDES
108PainSIDER
109ParesisSIDER
110Patellofemoral Pain SyndromeOFFSIDES
111Peritoneal DialysisOFFSIDES
112Pituitary Neoplasms8402624
8972233		CTD
113Poor quality sleepOFFSIDES
114Precancerous Conditions8402624
8972233		CTD
115Primary sequestrumOFFSIDES
116PruritusSIDER
117Pulmonary EmbolismSIDER
118Pulmonary thrombosisOFFSIDES
119PurulenceOFFSIDES
120Purulent dischargeOFFSIDES
121Pyogenic granulomaOFFSIDES
122Renal cystOFFSIDES
123RhinorrheaOFFSIDES
124SacroiliitisOFFSIDES
125ScleremaOFFSIDES
126Secondary sequestrumOFFSIDES
127SequestrectomyOFFSIDES
128Sinus antrostomyOFFSIDES
129Sinus operationOFFSIDES
130Sinus polypOFFSIDES
131SinusitisOFFSIDES
132Skin neoplasm excisionOFFSIDES
133Spermatocele16709447CTD
134Spinal column stenosisOFFSIDES
135StiffnessSIDER
136Suture ruptureOFFSIDES
137SweatingSIDER
138Testicular Neoplasms8972233CTD
139ThrombocytopeniaSIDER
140ThrombophlebitisSIDER
141ThrombosisSIDER
142Tooth ExtractionOFFSIDES
143Tooth InfectionOFFSIDES
144TremorSIDER
145Urge IncontinenceOFFSIDES
146Uterine CancerOFFSIDES
147Uterine PolypOFFSIDES
SIDER
148Vaginal DischargeSIDER
149Venous Thrombosis11816466CTD
150VertigoSIDER
151Visual ImpairmentSIDER
152Vitreous DetachmentOFFSIDES
153VomitingSIDER
154Wound DebridementOFFSIDES
155jaundiceSIDER
156nervous system disorderSIDER
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