MetaADEDB 2.0 @ LMMD
Portal Hypertension
(UMLS:C0020541)
Definition:
Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN.
UMLS ID:
C0020541
MeSH ID:
D006975
Classification:
Name:
Digestive System Diseases
MeSH Tree Number(s):
C06.552.494
Synonym(s)
1.
Portal Hypertension
2.
HYPERTENSION PORTAL
3.
Hypertension;portal
4.
PHT - Portal hypertension
5.
PORTAL HYPERTENSION
6.
Portal hypertension
7.
Portal hypertension syndrome
8.
hypertension portal
9.
hypertension; portal
10.
portal hypertension
Associated Drug(s)
NameNumber of ReportsReference(s)Data Source
1DidanosineFAERS: 36OFFSIDES
SIDER
US FAERS
2AzathioprineFAERS: 21US FAERS
3Ruxolitinib phosphateFAERS: 15US FAERS
4MercaptopurineFAERS: 13US FAERS
5MethotrexateFAERS: 8US FAERS
6TacrolimusFAERS: 8
Canada Vigilance: 1		Canada Vigilance
US FAERS
7BosentanFAERS: 6OFFSIDES
US FAERS
8Sitagliptin PhosphateFAERS: 6US FAERS
9SorafenibFAERS: 6US FAERS
10obeticholic acidFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
11CysteamineFAERS: 5US FAERS
12EverolimusFAERS: 5US FAERS
13Imatinib MesylateFAERS: 5US FAERS
14IsotretinoinFAERS: 5US FAERS
15DasatinibFAERS: 4US FAERS
16LenalidomideFAERS: 4US FAERS
17MetforminFAERS: 4US FAERS
18TadalafilFAERS: 4US FAERS
19ThalidomideFAERS: 4US FAERS
20nitisinoneFAERS: 4OFFSIDES
US FAERS
21AcetaminophenFAERS: 3OFFSIDES
US FAERS
22Duloxetine HydrochlorideFAERS: 3US FAERS
23PCI 32765FAERS: 3US FAERS
24PraziquantelFAERS: 3US FAERS
25TenofovirFAERS: 3OFFSIDES
US FAERS
26Ursodeoxycholic AcidFAERS: 3US FAERS
27lumacaftor, ivacaftor drug combinationFAERS: 3US FAERS
28pramlintideFAERS: 3US FAERS
29AlendronateFAERS: 2US FAERS
30AmiodaroneFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
31CanagliflozinFAERS: 2US FAERS
32CarbamazepineFAERS: 2US FAERS
33ClopidogrelFAERS: 2US FAERS
34ClozapineFAERS: 2US FAERS
35CyclosporineFAERS: 2US FAERS
36DiclofenacFAERS: 2US FAERS
37DoxycyclineFAERS: 2US FAERS
38EpoprostenolFAERS: 2US FAERS
39HydroxychloroquineFAERS: 2US FAERS
40LamivudineFAERS: 2OFFSIDES
US FAERS
41LeucovorinFAERS: 2US FAERS
42LevetiracetamFAERS: 2US FAERS
43MethotrexateFAERS: 2US FAERS
44OctreotideFAERS: 2US FAERS
45Piperacillin/tazobactamFAERS: 2US FAERS
46RosiglitazoneFAERS: 2US FAERS
47TelbivudineFAERS: 2US FAERS
48TerbinafineFAERS: 2US FAERS
49ThioguanineFAERS: 2OFFSIDES
SIDER
US FAERS
50WarfarinFAERS: 2US FAERS
51Zoledronic AcidFAERS: 2US FAERS
52ambrisentanFAERS: 2US FAERS
53apixabanFAERS: 2US FAERS
54tofacitinibFAERS: 2US FAERS
55treprostinilFAERS: 2OFFSIDES
US FAERS
56Abiraterone AcetateFAERS: 1US FAERS
57AcetylcysteineFAERS: 1US FAERS
58AcitretinFAERS: 1US FAERS
59AmiodaroneFAERS: 1US FAERS
60Amoxicillin-Potassium Clavulanate CombinationFAERS: 1US FAERS
61AzithromycinFAERS: 1US FAERS
62AztreonamFAERS: 1US FAERS
63BortezomibFAERS: 1OFFSIDES
US FAERS
64CID 129626832FAERS: 1US FAERS
65CapecitabineFAERS: 1US FAERS
66CarboplatinFAERS: 1US FAERS
67CaspofunginFAERS: 1US FAERS
68ChlorpropamideFAERS: 1US FAERS
69DecitabineFAERS: 1US FAERS
70DeferasiroxFAERS: 1US FAERS
71DeferoxamineFAERS: 1US FAERS
72DocetaxelFAERS: 1US FAERS
73EsomeprazoleFAERS: 1US FAERS
74FinasterideFAERS: 1US FAERS
75INCB018424FAERS: 1US FAERS
76LapatinibFAERS: 1US FAERS
77LeflunomideFAERS: 1US FAERS
78LopinavirFAERS: 1OFFSIDES
US FAERS
79MetforminFAERS: 1US FAERS
80MinocyclineFAERS: 1US FAERS
81Mycophenolic AcidFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
82NebivololFAERS: 1US FAERS
83NevirapineFAERS: 1OFFSIDES
US FAERS
84NuvaRingFAERS: 1US FAERS
85OctreotideFAERS: 1US FAERS
86OlanzapineFAERS: 1US FAERS
87OmeprazoleFAERS: 1US FAERS
88Paliperidone PalmitateFAERS: 1US FAERS
89Raloxifene HydrochlorideFAERS: 1US FAERS
90RifaximinFAERS: 1US FAERS
91RiluzoleFAERS: 1US FAERS
92RivaroxabanFAERS: 1US FAERS
93Rosuvastatin CalciumFAERS: 1US FAERS
94StavudineFAERS: 1OFFSIDES
US FAERS
95SulfamethoxazoleFAERS: 1US FAERS
96SunitinibFAERS: 1US FAERS
97TerbinafineFAERS: 1US FAERS
98ValganciclovirFAERS: 1US FAERS
99ValsartanFAERS: 1US FAERS
100VemurafenibFAERS: 1US FAERS
101VoseviFAERS: 1US FAERS
102acetaminophen, codeine drug combinationFAERS: 1US FAERS
103anagrelideFAERS: 1US FAERS
104cabozantinibFAERS: 1US FAERS
105cefuroxime axetilFAERS: 1OFFSIDES
US FAERS
106dolutegravirFAERS: 1US FAERS
107eltrombopagFAERS: 1US FAERS
108fexofenadineFAERS: 1US FAERS
109glycerol phenylbutyrateFAERS: 1US FAERS
110ledipasvir, sofosbuvir drug combinationFAERS: 1US FAERS
111liposomal doxorubicinFAERS: 1US FAERS
112macitentanFAERS: 1US FAERS
113olaparibFAERS: 1US FAERS
114palbociclibFAERS: 1US FAERS
115pirfenidoneFAERS: 1US FAERS
116reviparinFAERS: 1US FAERS
117rofecoxibFAERS: 1US FAERS
118sofosbuvir-velpatasvir drug combinationFAERS: 1US FAERS
119teduglutideFAERS: 1US FAERS
120telithromycinFAERS: 1OFFSIDES
US FAERS
121tipranavirFAERS: 1OFFSIDES
US FAERS
122valdecoxibFAERS: 1US FAERS
1232-[(E)-[1-(2-Amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid;(2S)-2,6-diaminohexanoic acidCanada Vigilance: 1Canada Vigilance
124AlbendazoleOFFSIDES
125AlcoholsOFFSIDES
126Aminocaproic AcidOFFSIDES
127Aspirin-oxycodone hydrochloride-oxycodone terephthalate combinationOFFSIDES
128AspirinCanada Vigilance: 1Canada Vigilance
129AtovaquoneOFFSIDES
130BenztropineOFFSIDES
131BezafibrateOFFSIDES
132BisacodylOFFSIDES
133BudesonideOFFSIDES
134BumetanideOFFSIDES
135BuprenorphineOFFSIDES
136CefadroxilOFFSIDES
137ClofarabineOFFSIDES
138CloxacillinOFFSIDES
139CodeineOFFSIDES
140CyclopentolateOFFSIDES
141DacarbazineOFFSIDES
142DactinomycinOFFSIDES
143DapsoneOFFSIDES
144DarunavirOFFSIDES
145EphedrineOFFSIDES
146EpoprostenolOFFSIDES
147FlavoxateOFFSIDES
148FluconazoleOFFSIDES
149FluorouracilOFFSIDES
150FosinoprilOFFSIDES
151FurosemideOFFSIDES
152GatifloxacinOFFSIDES
153GemfibrozilOFFSIDES
154Hydrocortisone sodium succinateOFFSIDES
155ImiquimodOFFSIDES
156IndinavirOFFSIDES
157IrinotecanOFFSIDES
158KetoconazoleOFFSIDES
159KetoprofenOFFSIDES
160LactuloseOFFSIDES
161LoratadineOFFSIDES
162Medroxyprogesterone AcetateOFFSIDES
163MedroxyprogesteroneOFFSIDES
164MelphalanOFFSIDES
165MeperidineOFFSIDES
166MethocarbamolOFFSIDES
167MethotrimeprazineOFFSIDES
168MetoclopramideOFFSIDES
169MidodrineOFFSIDES
170NadololOFFSIDES
171NaloxoneOFFSIDES
172NebivololOFFSIDES
173NelfinavirOFFSIDES
174NiacinOFFSIDES
175NitrazepamOFFSIDES
176OxazepamOFFSIDES
177PamidronateOFFSIDES
178PentamidineOFFSIDES
179PergolideOFFSIDES
180PiroxicamOFFSIDES
181Povidone-IodineOFFSIDES
182PrazepamOFFSIDES
183PyridoxineOFFSIDES
184QuinidineOFFSIDES
185RifampinOFFSIDES
186RitonavirOFFSIDES
187SaquinavirOFFSIDES
SIDER
188SevelamerOFFSIDES
189SevelamerOFFSIDES
190Sildenafil CitrateOFFSIDES
191SimethiconeOFFSIDES
192Sodium ferric gluconate complexOFFSIDES
193SulfadiazineOFFSIDES
194TazobactamOFFSIDES
195TenofovirOFFSIDES
196TestosteroneOFFSIDES
197ThiotepaOFFSIDES
198ThiothixeneOFFSIDES
199TolcaponeOFFSIDES
200TorsemideOFFSIDES
201TretinoinOFFSIDES
202TriamcinoloneOFFSIDES
203TrihexyphenidylOFFSIDES
204Trimethoprim, Sulfamethoxazole Drug CombinationOFFSIDES
205TrimipramineOFFSIDES
206ValganciclovirOFFSIDES
207VincristineOFFSIDES
208Vitamin K 1OFFSIDES
209ZidovudineOFFSIDES
210ZolpidemOFFSIDES
211abacavirOFFSIDES
212binedalineOFFSIDES
213calcipotrieneOFFSIDES
214chlorhexidine gluconateOFFSIDES
215efavirenzOFFSIDES
216fosamprenavirOFFSIDES
217gadodiamideOFFSIDES
218gadoversetamideOFFSIDES
219hydrocodone tartrate, ibuprofen drug combinationOFFSIDES
220liposomal amphotericin BOFFSIDES
221tetrazepamOFFSIDES
222urinastatinOFFSIDES
Similar ADE(s)
NameSemantic Similarity
1Fatty Liver42.9%
2Hepatitis42.9%
3Liver Cirrhosis42.9%
4Focal Nodular Hyperplasia42.9%
5Hepatic Insufficiency42.9%
6Steatohepatitis42.9%
7Biliary cirrhosis33.9%
8Hepatitis, Chronic31%
9Liver Failure31%
10Non-alcoholic Fatty Liver Disease31%
11Chronic active hepatitis31%
12Fatty Liver, Alcoholic30.1%
13Hepatitis, Alcoholic30.1%
14Liver Cirrhosis, Alcoholic30.1%
15Liver Diseases, Parasitic30%
16Hepatic Veno-Occlusive Disease28.6%
17Peliosis Hepatis28.6%
18Hepatopulmonary Syndrome28.6%
19Liver neoplasms28.1%
20Hepatomegaly27.9%
21Hepatic Vein Thrombosis27.4%
22Liver Abscess27.4%
23Budd-Chiari Syndrome27.4%
24Liver Failure, Acute25.4%
25End Stage Liver Disease25.4%
26Biliary Tract Diseases23.1%
27Gastrointestinal Diseases23.1%
28Pancreatic Diseases23.1%
29Massive Hepatic Necrosis22.7%
30Hepatitis, Animal22%
31Hepatitis, Viral, Human22%
32Chemical and Drug Induced Liver Injury21.4%
33Hepatorenal Syndrome20.5%
34Liver Cirrhosis, Experimental20.5%
35Liver Abscess, Amebic20.3%
36Hepatitis B, Chronic18.8%
37Hepatitis C, Chronic18.8%
38Autoimmune hepatitis17.2%
39Porphyrias, Hepatic16.4%
40Hepatocellular Adenoma16%
41Fascioliasis15.5%
42Echinococcosis, Hepatic15.4%
43Chemical and Drug Induced Liver Injury, Chronic15.3%
44Reye Syndrome15.1%
45Digestive System Neoplasms15%
46Bile Duct Diseases14.3%
47Cholelithiasis14.3%
48Chylous Ascites14.3%
49Esophageal Diseases14.3%
50Gastroenteritis14.3%
51Intestinal Diseases14.3%
52Pancreatic Insufficiency14.3%
53Pancreatitis14.3%
54Pneumoperitoneum14.3%
55Stomach Diseases14.3%
56Gastrointestinal Neoplasms14%
57Zollinger-Ellison syndrome13.9%
58Pancreatic Fistula13.9%
59Dysentery13.6%
60Enteritis13.6%
61Enterocolitis13.6%
62Esophagitis13.6%
63Gastritis13.6%
64Inflammatory Bowel Diseases13.6%
65Cholecystolithiasis13.6%
66Hepatitis, Viral, Animal13.5%
67Liver Neoplasms, Experimental13.5%
68Hepatitis E13%
69Hepatitis B12.8%
70Hepatitis C12.8%
71Proctocolitis12.7%
72Hepatitis A12.7%
73Hepatic Encephalopathy12.5%
74Duodenitis12.4%
75Ileitis12.4%
76Erosive Duodenitis12.4%
77Colitis12.4%
78Duodenogastric Reflux12.4%
79Peptic Ulcer12.4%
80Proctitis12.4%
81Choledocholithiasis12.4%
82Mesenteric vascular insufficiency12.3%
83Bile Duct Neoplasms12.1%
84gallbladder neoplasm12.1%
85Intestinal Neoplasms12.1%
86Stomach Neoplasms12.1%
87Esophageal Atresia12.1%
88Intestinal Atresia12.1%
89Mesenteric Vascular Occlusion12.1%
90Intestinal Fistula12%
91Enterocutaneous Fistula12%
92Variegate Porphyria11.9%
93Acute intermittent porphyria11.9%
94Porphyria Cutanea Tarda11.9%
95Colorectal Neoplasms11.7%
96Crohn Disease11.1%
97Duodenal Obstruction11.1%
98Peritoneal Neoplasms11.1%
99Enterocolitis, Neutropenic11.1%
100Necrotizing Enterocolitis11.1%
101Pouchitis11%
102Cecal Neoplasms10.9%
103Duodenal Neoplasms10.9%
104Rectal Fistula10.6%
105Anal Fistula10.6%
106Duodenal Ulcer10.5%
107Peptic Ulcer Perforation10.5%
108Gastric ulcer10.5%
109Cecal Diseases10.3%
110Cholangitis10.3%
111Cholecystitis10.3%
112Cholestasis10.3%
113Colonic Diseases10.3%
114Common Bile Duct Diseases10.3%
115Esophageal Stenosis10.3%
116Ileal Diseases10.3%
117Intestinal Obstruction10.3%
118Intestinal Perforation10.3%
119Jejunal Diseases10.3%
120Pneumatosis Cystoides Intestinalis10.3%
121Rectal Diseases10.3%
122Gastric Dilatation10.3%
123Pancreatitis, Chronic10.3%
124Gastric outlet obstruction10.3%
125Cronkhite-Canada Syndrome10.3%
126Intestinal Polyposis10.3%
127Gastrointestinal Stromal Tumors10.1%
128Esophageal Neoplasms10.1%
129Anus Neoplasms9.8%
130Sigmoid Neoplasms9.8%
131Choledochal Cyst9.7%
132Appendiceal Neoplasms9.7%
133Colonic Neoplasms9.7%
134Rectal Neoplasms9.7%
135Colonic Pseudo-Obstruction9.6%
136Pancreatic Cyst9.5%
137Anus, Imperforate9.3%
138Gastrointestinal Hemorrhage9.3%
139Hemoperitoneum9.3%
140Mesenteric Panniculitis9.3%
141Pancreatic Neoplasm9.3%
142Panniculitis, Peritoneal9.3%
143Peritonitis9.3%
144Peritoneal Fibrosis9.3%
145Encapsulating Peritoneal Sclerosis9.3%
146Anorectal Malformations9.3%
147Appendicitis9.2%
148Biliary Fistula9.2%
149Gastric Fistula9.2%
150Tuberculosis, Gastrointestinal9.1%
151Cholestasis, Extrahepatic8.5%
152Biliary Dyskinesia8.5%
153Cholangitis, Sclerosing8.5%
154Colonic Diseases, Functional8.5%
155Esophageal motility disorders8.5%
156Fecal Incontinence8.5%
157Fecal Impaction8.5%
158Intussusception8.5%
159Mallory-Weiss Syndrome8.5%
160Megacolon8.5%
161Pyloric Stenosis8.5%
162Acalculous Cholecystitis8.5%
163Ileus8.5%
164Meconium ileus8.5%
165Enterocolitis, Pseudomembranous8.3%
166pseudomembranous colitis8.3%
167Dysentery, Bacillary8.3%
168Colitis, Ischemic8%
169Esophageal Achalasia7.6%
170Anal Fissure7.6%
171Intestinal Pseudo-Obstruction7.6%
172Irritable Bowel Syndrome7.6%
173Superior Mesenteric Artery Syndrome7.6%
174Emphysematous Cholecystitis7.6%
175Neurogenic Bowel7.6%
176Sphincter of Oddi Dysfunction7.6%
177Anal Ulcer7.6%
178Adenomatous Polyposis Coli7.5%
179Esophageal Perforation7.3%
180Intestinal Diseases, Parasitic7.3%
181Zellweger Syndrome7.2%
182Barrett Esophagus7%
183Deglutition Disorders7%
184Achlorhydria6.8%
185Esophageal and Gastric Varices6.8%
186Pancreatic Pseudocyst6.8%
187Gastric Antral Vascular Ectasia6.8%
188Peptic Ulcer Hemorrhage6.7%
189Gastroparesis6.7%
190Pancreatitis, Alcoholic6.7%
191Hepatolenticular Degeneration6.6%
192Rift Valley Fever6.6%
193Hemorrhoids5.7%
194Cystic Fibrosis5.7%
195Afferent Loop Syndrome5.6%
196Celiac Disease5.6%
197Short Bowel Syndrome5.6%
198Sprue, Tropical5.6%
199Steatorrhea5.6%
200Rectocele5.6%
201Sprue5.6%
202Diverticulitis5.6%
203Dumping Syndrome5.6%
204Rectal Prolapse5.6%
205Congenital Hyperinsulinism5.5%
206Melena5.1%
207Pruritus Ani5%
208Hematemesis5%
209Carcinoma, Pancreatic Ductal4.9%
210Laryngopharyngeal Reflux4.8%
211insulinoma4.6%
212Gastrinoma4.6%
213Glucagonoma4.6%
214Giardiasis4.3%
215Diverticulum4.2%
216Diverticulosis4.2%
217Vipoma4%
218Nesidioblastosis4%
219Peutz-Jeghers Syndrome3.4%
220Lactose Intolerance3.3%
221Cryptosporidiosis2.4%
222CREST Syndrome2.1%
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