MetaADEDB 2.0 @ LMMD
Colchicine
(IAKHMKGGTNLKSZ-INIZCTEOSA-N)
Structure
SMILES
COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC
Molecular Formula:
C22H25NO6
Molecular Weight:
399.437
Log P:
3.2625
Hydrogen Bond Acceptor:
7
Hydrogen Bond Donor:
1
TPSA:
83.09
CAS Number(s):
64-86-8; 30512-31-3
Synonym(s)
1.
Colchicine
2.
Colchicine, (+-)-Isomer
3.
Colchicine, (R)-Isomer
External Link(s)
MeSHD003078
PubChem Compound6167
BindingDB50014846
ChEBI27882
CHEMBLCHEMBL107
DrugBankDB08117
DrugCentral726
IUPHAR/BPS Guide to PHARMACOLOGY2367
KEGGcpd:C07592
dr:D00570
Therapeutic Target DatabaseD09DHY
ZINC621853
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Toxicity to various agentsFAERS: 152
Canada Vigilance: 2		Canada Vigilance
US FAERS
2Drug ineffectiveFAERS: 101
Canada Vigilance: 1		Canada Vigilance
US FAERS
3VomitingFAERS: 70
Canada Vigilance: 4		10383025
16240705
20131255		CTD
SIDER
Canada Vigilance
US FAERS
4NauseaFAERS: 58
Canada Vigilance: 5		10383025CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
5No adverse eventFAERS: 54US FAERS
6OverdoseFAERS: 54US FAERS
7Suicide attemptFAERS: 45US FAERS
8Abdominal PainFAERS: 27
Canada Vigilance: 6		10383025
15318531
17497454		CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
9DizzinessFAERS: 25
Canada Vigilance: 2		10383025CTD
OFFSIDES
Canada Vigilance
US FAERS
10Product substitution issueFAERS: 23US FAERS
11Product use issueFAERS: 22US FAERS
12GoutFAERS: 21

View details

1064465
2023222
2265497
2360262
3035372
5760170
6071127
7725894
9491303
9848464
11096285
11810174
11876034
12410059
15585444
16669978
17049607
19893064
 		CTD
OFFSIDES
SIDER
US FAERS
13AstheniaFAERS: 20
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
SIDER
US FAERS
14HypotensionFAERS: 18
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
15Accidental exposureFAERS: 16US FAERS
16Cardiac ArrestFAERS: 16
Canada Vigilance: 2		Canada Vigilance
US FAERS
17PainFAERS: 1620131255CTD
OFFSIDES
US FAERS
18PancytopeniaFAERS: 14
Canada Vigilance: 1

View details

737005
15088997
15656036
17505274
 		CTD
SIDER
Canada Vigilance
US FAERS
19Aspartate Aminotransferase IncreasedFAERS: 13SIDER
US FAERS
20Blood lactate dehydrogenase increasedFAERS: 13US FAERS
21Completed SuicideFAERS: 13US FAERS
22DehydrationFAERS: 13OFFSIDES
SIDER
US FAERS
23Drug prescribing errorFAERS: 13US FAERS
24MyalgiaFAERS: 11SIDER
US FAERS
25Abdominal discomfortFAERS: 10OFFSIDES
SIDER
US FAERS
26Accidental exposure to productFAERS: 10US FAERS
27RhabdomyolysisFAERS: 1014713183
15389652
17497454		CTD
OFFSIDES
SIDER
US FAERS
28ThrombocytopeniaFAERS: 106532622
16240705
17497454		CTD
SIDER
US FAERS
29Drug resistanceFAERS: 9US FAERS
30LeukocytosisFAERS: 9US FAERS
31UrticariaFAERS: 9SIDER
US FAERS
32Acute kidney injuryFAERS: 8
Canada Vigilance: 1		16495211CTD
Canada Vigilance
US FAERS
33Blood creatine phosphokinase increasedFAERS: 8OFFSIDES
SIDER
US FAERS
34FatigueFAERS: 820824538
21145509		CTD
OFFSIDES
SIDER
US FAERS
35PregnancyFAERS: 8US FAERS
36Alanine Aminotransferase IncreasedFAERS: 7OFFSIDES
SIDER
US FAERS
37Drug dispensing errorFAERS: 7US FAERS
38Familial Mediterranean FeverFAERS: 7

View details

1499522
1575022
9848464
12910572
14632592
16889161
17505274
20661070
 		CTD
US FAERS
39HeadacheFAERS: 7
Canada Vigilance: 1		10383025CTD
SIDER
Canada Vigilance
US FAERS
40HepatotoxicityFAERS: 7US FAERS
41LeukopeniaFAERS: 7
Canada Vigilance: 2		6532622
16240705		CTD
SIDER
Canada Vigilance
US FAERS
42Weight decreasedFAERS: 7
Canada Vigilance: 1		Canada Vigilance
US FAERS
43Accidental exposure to product by childFAERS: 6US FAERS
44AlopeciaFAERS: 6405656
843157
15088997		CTD
SIDER
US FAERS
45ArthralgiaFAERS: 6SIDER
US FAERS
46Blood creatinine decreasedFAERS: 6US FAERS
47Blood urea increasedFAERS: 6US FAERS
48ConstipationFAERS: 6US FAERS
49Disseminated Intravascular CoagulationFAERS: 64562795CTD
SIDER
US FAERS
50DyspepsiaFAERS: 6US FAERS
51Inappropriate schedule of drug administrationFAERS: 6US FAERS
52MalaiseFAERS: 6
Canada Vigilance: 1		Canada Vigilance
US FAERS
53Metabolic acidosisFAERS: 6SIDER
US FAERS
54Oropharyngeal painFAERS: 6US FAERS
55Prescribed overdoseFAERS: 6US FAERS
56Accidental overdoseFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
57Back PainFAERS: 5US FAERS
58CardiotoxicityFAERS: 5US FAERS
59Drug dose omissionFAERS: 5US FAERS
60Economic problemFAERS: 5US FAERS
61Incorrect route of drug administrationFAERS: 5US FAERS
62Myocardial InfarctionFAERS: 5US FAERS
63MyopathyFAERS: 5SIDER
US FAERS
64PneumoniaFAERS: 5US FAERS
65SwellingFAERS: 5US FAERS
66Abdominal tendernessFAERS: 4US FAERS
67Blood creatinine increasedFAERS: 4OFFSIDES
SIDER
US FAERS
68BradycardiaFAERS: 4OFFSIDES
US FAERS
69Cerebrovascular accidentFAERS: 4US FAERS
70Chest PainFAERS: 4OFFSIDES
US FAERS
71Incorrect dose administeredFAERS: 4
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
72LethargyFAERS: 4OFFSIDES
US FAERS
73PallorFAERS: 4US FAERS
74PalpitationsFAERS: 4US FAERS
75PancreatitisFAERS: 4843157
15088997		CTD
US FAERS
76PresyncopeFAERS: 4US FAERS
77PruritusFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
78TachycardiaFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
79Trisomy 21FAERS: 4US FAERS
80Wrong technique in product usage processFAERS: 4US FAERS
81intensive careFAERS: 4US FAERS
82AgeusiaFAERS: 3US FAERS
83ArthritisFAERS: 3US FAERS
84Blood pH decreasedFAERS: 3US FAERS
85CyanosisFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
86Disease recurrenceFAERS: 3US FAERS
87ErythemaFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
88Feeling abnormalFAERS: 3US FAERS
89GastroenteritisFAERS: 3843157CTD
US FAERS
90HypersensitivityFAERS: 3SIDER
US FAERS
91HypophagiaFAERS: 3US FAERS
92Lip swellingFAERS: 3US FAERS
93LymphadenopathyFAERS: 3US FAERS
94Medication ErrorFAERS: 3US FAERS
95Mental status changesFAERS: 3OFFSIDES
US FAERS
96NeutropeniaFAERS: 3SIDER
US FAERS
97Respiratory distressFAERS: 3US FAERS
98SepsisFAERS: 3405656
17505274		CTD
US FAERS
99SinusitisFAERS: 3US FAERS
100SyncopeFAERS: 3US FAERS
101Therapy cessationFAERS: 3US FAERS
102Throat irritationFAERS: 3US FAERS
103Ventricular FibrillationFAERS: 3US FAERS
104White blood cell count decreasedFAERS: 3US FAERS
105AcidosisFAERS: 2US FAERS
106Activities of daily living impairedFAERS: 2US FAERS
107AgitationFAERS: 2US FAERS
108AnxietyFAERS: 2US FAERS
109AphagiaFAERS: 2US FAERS
110Cerebral PalsyFAERS: 2US FAERS
111Clostridium difficile infectionFAERS: 2US FAERS
112Corneal PerforationFAERS: 2US FAERS
113DiscomfortFAERS: 2US FAERS
114Drug administered to patient of inappropriate ageFAERS: 2US FAERS
115Drug level increasedFAERS: 2US FAERS
116Drug toxicityFAERS: 2OFFSIDES
US FAERS
117FlatulenceFAERS: 2US FAERS
118Gastric ulcerFAERS: 2US FAERS
119General physical health deteriorationFAERS: 2OFFSIDES
US FAERS
120HepatomegalyFAERS: 2US FAERS
121Histiocytosis haematophagicFAERS: 2US FAERS
122Intercepted product dispensing errorFAERS: 2US FAERS
123Intestinal ObstructionFAERS: 2US FAERS
124Invasive Ductal Breast CarcinomaFAERS: 2US FAERS
125Joint swellingFAERS: 2US FAERS
126KeratoconusFAERS: 2US FAERS
127NasopharyngitisFAERS: 2OFFSIDES
US FAERS
128PCO2 decreasedFAERS: 2US FAERS
129Paternal exposure before pregnancyFAERS: 2US FAERS
130Peripheral swellingFAERS: 2US FAERS
131Product quality issueFAERS: 2US FAERS
132Rash erythematousFAERS: 2US FAERS
133Renal painFAERS: 2US FAERS
134SomnolenceFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
135SplenomegalyFAERS: 2US FAERS
136Stevens-Johnson SyndromeFAERS: 2US FAERS
137StressFAERS: 2US FAERS
138TalipesFAERS: 2US FAERS
139Toxic Epidermal NecrolysisFAERS: 2US FAERS
140Troponin I increasedFAERS: 2US FAERS
141Visual ImpairmentFAERS: 2US FAERS
142Abdominal rigidityFAERS: 1US FAERS
143Abdominal symptomFAERS: 1US FAERS
144Accidental drug intake by childFAERS: 1US FAERS
145Acute cardiac eventFAERS: 1US FAERS
146Acute respiratory failureFAERS: 1US FAERS
147Adverse eventFAERS: 1US FAERS
148Alanine aminotransferase abnormalFAERS: 1US FAERS
149Ankle FractureFAERS: 1US FAERS
150AnuriaFAERS: 117497454CTD
SIDER
US FAERS
151Apparent deathFAERS: 1US FAERS
152ArthropathyFAERS: 1OFFSIDES
US FAERS
153Aspartate aminotransferase abnormalFAERS: 1US FAERS
154Atrial FibrillationFAERS: 1US FAERS
155Base excess decreasedFAERS: 1US FAERS
156Biopsy muscle abnormalFAERS: 1US FAERS
157Blood creatinine abnormalFAERS: 1US FAERS
158Blood glucose decreasedFAERS: 1OFFSIDES
US FAERS
159Blood osmolarity decreasedFAERS: 1US FAERS
160Blood potassium decreasedFAERS: 1US FAERS
161Blood sodium decreasedFAERS: 1US FAERS
162Blood urea abnormalFAERS: 1US FAERS
163Bone marrow depressionFAERS: 1US FAERS
164Bowel movement irregularityFAERS: 1US FAERS
165Cardiac DeathFAERS: 1US FAERS
166Cardiac FlutterFAERS: 1US FAERS
167Cardiac enzymes increasedFAERS: 1US FAERS
168Carpal Tunnel SyndromeFAERS: 1US FAERS
169Central nervous system lesionFAERS: 1US FAERS
170Cerebral disorderFAERS: 1US FAERS
171ChillsFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
172Congenital HypothyroidismFAERS: 1US FAERS
173ConjunctivitisFAERS: 1US FAERS
174CraniosynostosisFAERS: 1US FAERS
175Dark circles under eyesFAERS: 1US FAERS
176Depressed Level of ConsciousnessFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
177Depressed moodFAERS: 1US FAERS
178DiplopiaFAERS: 1US FAERS
179Disease complicationFAERS: 1US FAERS
180DiverticulitisFAERS: 1
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
181Drug abuseFAERS: 1US FAERS
182Drug administration errorFAERS: 1US FAERS
183Drug effect delayedFAERS: 1US FAERS
184Drug effect incompleteFAERS: 1US FAERS
185Drug ineffective for unapproved indicationFAERS: 1US FAERS
186Duodenal UlcerFAERS: 1US FAERS
187DysgeusiaFAERS: 1US FAERS
188DysphoniaFAERS: 1US FAERS
189DysuriaFAERS: 1US FAERS
190EcchymosisFAERS: 1US FAERS
191Echocardiogram abnormalFAERS: 1US FAERS
192EczemaFAERS: 1US FAERS
193Electrolyte imbalanceFAERS: 1US FAERS
194EmbolismFAERS: 1US FAERS
195Enzyme abnormalityFAERS: 1US FAERS
196EpistaxisFAERS: 1OFFSIDES
US FAERS
197EructationFAERS: 1US FAERS
198Extra dose administeredFAERS: 1US FAERS
199Feeling jitteryFAERS: 1US FAERS
200FibromyalgiaFAERS: 1US FAERS
201FlushingFAERS: 1US FAERS
202Gait inabilityFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
203GastritisFAERS: 1US FAERS
204Granulocytes abnormalFAERS: 1US FAERS
205HepatitisFAERS: 1OFFSIDES
US FAERS
206HypoventilationFAERS: 1US FAERS
207HypoxiaFAERS: 1OFFSIDES
US FAERS
208Impaired work abilityFAERS: 1US FAERS
209IncontinenceFAERS: 1OFFSIDES
US FAERS
210Incorrect drug administration durationFAERS: 1US FAERS
211Incorrect drug administration rateFAERS: 1US FAERS
212InfectionFAERS: 1US FAERS
213InflammationFAERS: 19848464
15318531		CTD
US FAERS
214Infrequent bowel movementsFAERS: 1US FAERS
215Intentional drug misuseFAERS: 1US FAERS
216Intentional product use issueFAERS: 1US FAERS
217Intercepted drug prescribing errorFAERS: 1US FAERS
218Intercepted product prescribing errorFAERS: 1US FAERS
219Intestinal infarctionFAERS: 1US FAERS
220IridoceleFAERS: 1US FAERS
221Ligament painFAERS: 1US FAERS
222Ligament ruptureFAERS: 1US FAERS
223Limb discomfortFAERS: 1US FAERS
224Livedo ReticularisFAERS: 1US FAERS
225Loss of personal independence in daily activitiesFAERS: 1US FAERS
226LymphopeniaFAERS: 1US FAERS
227Maternal exposure during breast feedingFAERS: 1US FAERS
228MicrocephalyFAERS: 1US FAERS
229Motion SicknessFAERS: 1US FAERS
230Multi-organ disorderFAERS: 1US FAERS
231Musculoskeletal chest painFAERS: 1OFFSIDES
US FAERS
232MydriasisFAERS: 1US FAERS
233Neck PainFAERS: 1US FAERS
234Nephrogenic Diabetes InsipidusFAERS: 1US FAERS
235NephrolithiasisFAERS: 1US FAERS
236Neutrophil Pelger-Huet anomaly presentFAERS: 1US FAERS
237Night sweatsFAERS: 1US FAERS
238OligodipsiaFAERS: 1US FAERS
239OliguriaFAERS: 1
Canada Vigilance: 1		16240705
17497454		CTD
SIDER
Canada Vigilance
US FAERS
240Oral painFAERS: 1US FAERS
241Pericardial effusionFAERS: 1OFFSIDES
US FAERS
242PhotophobiaFAERS: 1US FAERS
243PneumothoraxFAERS: 1OFFSIDES
US FAERS
244Polyarteritis NodosaFAERS: 1US FAERS
245Pre-EclampsiaFAERS: 1US FAERS
246Prescription drug used without a prescriptionFAERS: 1US FAERS
247Pulmonary EmbolismFAERS: 1US FAERS
248Pulmonary FibrosisFAERS: 1US FAERS
249Respiratory FailureFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
250Respiratory arrestFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
251Restless Legs SyndromeFAERS: 1US FAERS
252RestlessnessFAERS: 1US FAERS
253ScabFAERS: 1US FAERS
254Serum amyloid A protein increasedFAERS: 1US FAERS
255ShockFAERS: 1
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
256Skin UlcerFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
257Skin WrinklingFAERS: 1US FAERS
258StomatitisFAERS: 1SIDER
US FAERS
259Sudden deathFAERS: 1US FAERS
260SynovitisFAERS: 1US FAERS
261Systolic dysfunctionFAERS: 1US FAERS
262TachyphreniaFAERS: 1US FAERS
263ThrombocytosisFAERS: 1US FAERS
264Tongue erythemaFAERS: 1US FAERS
265Transaminases increasedFAERS: 1US FAERS
266Troponin increasedFAERS: 1US FAERS
267UlcerFAERS: 1US FAERS
268Unevaluable eventFAERS: 1US FAERS
269Urinary IncontinenceFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
270Urinary tract infectionFAERS: 1US FAERS
271Urine flow decreasedFAERS: 1US FAERS
272Walking aid userFAERS: 1US FAERS
273Wheelchair userFAERS: 1US FAERS
274jaundiceFAERS: 1
Canada Vigilance: 1		15318531CTD
Canada Vigilance
US FAERS
275nervous system disorderFAERS: 1SIDER
US FAERS
276Abdominal CrampsSIDER
277Abnormalities, Drug-Induced4012644CTD
278Acetonaemic vomitingOFFSIDES
279Acid refluxOFFSIDES
280AgranulocytosisSIDER
281AlveolitisOFFSIDES
282Amnesia2924118CTD
283Amyloidosis1499522
1604496
17505274		CTD
284Anemia, Megaloblastic15656036CTD
285Anemia6532622CTD
286Aneuploidy28087838CTD
287Aneurysm5760170CTD
288AngioedemaSIDER
289AnhedoniaOFFSIDES
290AnorexiaOFFSIDES
291ArteriosclerosisOFFSIDES
292Arteriovenous fistula thrombosisOFFSIDES
293Arthritis, Gouty

View details

3701734
5655316
14713183
17497454
20661070
 		CTD
294Arthritis, Psoriatic17408446CTD
295AscitesOFFSIDES
296Ataxia9460408CTD
297AtelectasisOFFSIDES
298Atrial FlutterOFFSIDES
299AuraOFFSIDES
300Avascular necrosisOFFSIDES
301Axonal neuropathySIDER
302AzoospermiaSIDER
303Band neutrophil percentage increasedOFFSIDES
304Behcet Syndrome

View details

2566048
6788612
9775117
9848464
11087798
12692989
15870978
 		CTD
305Benign Prostatic HyperplasiaOFFSIDES
306Bladder painSIDER
307Bladder spasmSIDER
308Blood 1,25-dihydroxycholecalciferol decreasedOFFSIDES
309Blood GlucoseOFFSIDES
310Blood chloride decreasedOFFSIDES
311Blood pressure fluctuationOFFSIDES
312Blood uric acidOFFSIDES
313Bone Marrow Diseases405656
737005
15088997		CTD
314Bone marrow toxicityOFFSIDES
315Bone painOFFSIDES
316Brain Diseases7403241CTD
317Brain Injuries2924118CTD
318Breast CystOFFSIDES
319BronchitisOFFSIDES
320CalcinosisOFFSIDES
321CalciphylaxisOFFSIDES
322CellulitisOFFSIDES
323Chemical and Drug Induced Liver Injury22331495
26881866		CTD
324Choking sensationOFFSIDES
325Cholestasis3733464
15318531		CTD
326ChromaturiaCanada Vigilance: 1Canada Vigilance
OFFSIDES
327CirrhosisOFFSIDES
328Clostridium difficile colitisOFFSIDES
329ClumsinessOFFSIDES
330Cognition Disorders

View details

17135773
17652827
18980205
18992766
 		CTD
331Concomitant disease aggravatedOFFSIDES
332Condylomata Acuminata843157CTD
333ConfabulationOFFSIDES
334Congenital tricuspid valve incompetenceOFFSIDES
335Conjunctival depositOFFSIDES
336Creatine Phosphokinase IncreasedSIDER
337Creatinine increasedSIDER
338DemyelinationOFFSIDES
339DermatitisSIDER
340DiabetesOFFSIDES
341Diabetic RetinopathyOFFSIDES
342Diarrhea

View details

5538601
16240705
17497454
20131255
 		CTD
OFFSIDES
343Diastolic dysfunctionOFFSIDES
344DiverticulumOFFSIDES
345Down Syndrome4179378
4182734		CTD
346Drug Overdose17505274CTD
347Drug administered at inappropriate siteOFFSIDES
348Dry skinOFFSIDES
349Dyspnea14744269CTD
350Ejection fraction abnormalOFFSIDES
351Electromechanical dissociationOFFSIDES
352Emotional distressOFFSIDES
353EnteritisOFFSIDES
354Enterocolitis15088997CTD
OFFSIDES
355Eye painOFFSIDES
356Flat affectOFFSIDES
357Fluid overloadOFFSIDES
358GangreneOFFSIDES
359Gastrointestinal Diseases10455999
17505274		CTD
360Gastrointestinal PainSIDER
361Gastrointestinal toxicityOFFSIDES
362Genital burning sensationOFFSIDES
363Glaucoma, Open-Angle12446362CTD
364GlomerulonephritisOFFSIDES
365GranulocytosisOFFSIDES
366Guillain-Barre Syndrome17097509CTD
367HemiparesisOFFSIDES
368HemiplegiaOFFSIDES
369Hemorrhage405656CTD
370Hepatitis AOFFSIDES
371Hepatitis B, Chronic9701529CTD
372HepatosplenomegalyOFFSIDES
373HyperkeratosisOFFSIDES
374Hypernatremia10383025CTD
375HyperpigmentationOFFSIDES
376HypertransaminasaemiaOFFSIDES
377Hyperuricemia6071127CTD
378Hyponatremia405656CTD
379HypothyroidismSIDER
380Hypotrichosis17505274CTD
381ImmunosuppressionOFFSIDES
382Infusion site mobility decreasedOFFSIDES
383Injection site inflammationCanada Vigilance: 1Canada Vigilance
384Injection site painCanada Vigilance: 1Canada Vigilance
385Insulin-requiring type 2 diabetes mellitusOFFSIDES
386Intestinal Diseases14623787CTD
387Iron OverloadOFFSIDES
388Joint Range of Motion DecreasedOFFSIDES
389Joint stiffnessOFFSIDES
390Kidney Diseases3122121CTD
391Kidney FailureOFFSIDES
392Lactose IntoleranceSIDER
393Large intestine perforationOFFSIDES
394Liver Cirrhosis23146695CTD
395Liver Failure, Acute15088997CTD
396Liver diseases2566048
10455999
17497454		CTD
397Lower respiratory tract infection viralOFFSIDES
398LymphedemaOFFSIDES
399Lysosomal Storage Diseases28551711CTD
400MalabsorptionSIDER
401MalnutritionSIDER
402Memory Disorders9449054
18992766		CTD
403Micronuclei, Chromosome-Defective28389280
29733868		CTD
404Migraine with AuraOFFSIDES
405Movement Disorders21494842CTD
406Mucosal erosionOFFSIDES
407Multiple Myeloma1064465CTD
408Multiple Organ Failure15088997
17497454
17505274		CTD
409Muscle Weakness

View details

5538601
7725894
8234983
9323377
10904571
11810174
12122515
14632592
14744269
15585444
16669978
17049607
17421021
19143894
20661070
 		CTD
OFFSIDES
410Muscle necrosisOFFSIDES
411Muscular Atrophy8234983CTD
412Musculoskeletal discomfortSIDER
413Musculoskeletal stiffnessOFFSIDES
414MyelosuppressionSIDER
415Myoglobin blood increasedOFFSIDES
416Myoglobinuria1499522CTD
417Myotonia8965841
9533795		CTD
SIDER
418Myotonic Disorders12954545CTD
419Necrosis171611
12576187
26881866		CTD
420Neoplasms21472861CTD
421NephroangiosclerosisOFFSIDES
422Nephrogenic Fibrosing DermopathyOFFSIDES
423Neural Tube Defects4012644CTD
424NeuritisSIDER
425Neuromuscular Diseases

View details

843157
1466611
1472131
1485821
1604496
2525778
2725561
3035372
7725894
7923972
8965841
9491303
9533795
9809829
10686640
12122515
12371628
12692989
14573738
16148013
16248366
16669978
17097509
17421021
18490798
 		CTD
426Neuropathic painOFFSIDES
427Ocular icterusOFFSIDES
428OligospermiaSIDER
429Optic Atrophy6187703CTD
430Oropharyngeal discomfortOFFSIDES
431OrthopneaOFFSIDES
432PemphigusOFFSIDES
433PericarditisOFFSIDES
434Peripheral Nervous System Diseases9491303
11921069		CTD
435Peripheral motor neuropathySIDER
436PetechiaeCanada Vigilance: 1Canada Vigilance
437Pharyngitis bacterialOFFSIDES
438Pharyngolaryngeal PainSIDER
439PhlebitisCanada Vigilance: 1Canada Vigilance
440PolyneuropathyOFFSIDES
441Polyuria10383025
16708563		CTD
442Porphyria Cutanea Tarda4105790CTD
443Product prescribing issueCanada Vigilance: 1Canada Vigilance
444Productive CoughOFFSIDES
445Propofol Infusion SyndromeOFFSIDES
446Psoriasis9848464CTD
447PurpuraSIDER
448Pyoderma GangrenosumOFFSIDES
449Quadriplegia16148013CTD
450Quality of life decreasedOFFSIDES
451Reflex, Abnormal8234983CTD
452Renal Insufficiency

View details

405656
1499522
10455999
16240705
17497454
 		CTD
453Renal cystOFFSIDES
454Renal tubular necrosisOFFSIDES
455Respiratory Insufficiency843157CTD
456Retinal Artery OcclusionOFFSIDES
457RhinorrheaOFFSIDES
458Seizures6509321
6884477		CTD
459Septic ShockOFFSIDES
460SerositisOFFSIDES
461Shwartzman Phenomenon4562795CTD
462Skin IndurationOFFSIDES
463Skin hypertrophyOFFSIDES
464Skin lesionOFFSIDES
465Skin tightnessOFFSIDES
466Striatonigral Degeneration18564367CTD
467Sweet Syndrome9848464CTD
468Tension HeadacheOFFSIDES
469Terminal stateOFFSIDES
470ThrombophlebitisCanada Vigilance: 1Canada Vigilance
471Unresponsive to stimuliCanada Vigilance: 1Canada Vigilance
OFFSIDES
472Urinary tract infection fungalOFFSIDES
473Vacuolar myopathy

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8234983
9394328
11810174
12399640
12954545
16669978
 		CTD
474Vascular purpuraSIDER
475Viral upper respiratory tract infectionOFFSIDES
476Vision Disorders17421021CTD
477Vitamin B 12 Deficiency15656036CTD
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