MetaADEDB 2.0 @ LMMD
Ethosuximide
(HAPOVYFOVVWLRS-UHFFFAOYSA-N)
Structure
SMILES
CC1(CC)CC(=O)NC1=O
Type(s)
Approved
ATC code(s)
N03AD01; N03AD51
Molecular Formula:
C7H11NO2
Molecular Weight:
141.168
Log P:
0.7780
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
1
TPSA:
46.17
CAS Number(s):
77-67-8
Synonym(s)
1.
Ethosuximide
2.
Ethosuccimid
3.
Emeside
4.
Ethylmethylsuccimide
5.
Ethymal
6.
Etosuximida Faes
7.
Petnidan
8.
Pyknolepsinum
9.
Suksilep
10.
Suxilep
11.
Zarontin
12.
Faes, Etosuximida
External Link(s)
MeSHD005013
PubChem Compound3291
BindingDB50240424
ChEBI4887
CHEMBLCHEMBL696
DrugBankDB00593
DrugCentral1087
IUPHAR/BPS Guide to PHARMACOLOGY7182
KEGGcpd:C07505
dr:D00539
Therapeutic Target DatabaseD0Q4XQ
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 22OFFSIDES
US FAERS
2HeadacheFAERS: 109776542CTD
SIDER
US FAERS
3FatigueFAERS: 9OFFSIDES
SIDER
US FAERS
4Product taste abnormalFAERS: 9US FAERS
5Pharmaceutical product complaintFAERS: 8OFFSIDES
US FAERS
6Product substitution issueFAERS: 8US FAERS
7VomitingFAERS: 8623072CTD
SIDER
US FAERS
8ArthralgiaFAERS: 79776542CTD
US FAERS
9EpilepsyFAERS: 6812426CTD
US FAERS
10Poor quality drug administeredFAERS: 6OFFSIDES
US FAERS
11DizzinessFAERS: 5SIDER
US FAERS
12NauseaFAERS: 5SIDER
US FAERS
13Abdominal discomfortFAERS: 4SIDER
US FAERS
14Depressed moodFAERS: 4US FAERS
15Immune thrombocytopenic purpuraFAERS: 4US FAERS
16Joint swellingFAERS: 4US FAERS
17Abdominal PainFAERS: 3SIDER
US FAERS
18AngerFAERS: 3US FAERS
19AnxietyFAERS: 3US FAERS
20AstheniaFAERS: 3SIDER
US FAERS
21Benign Rolandic EpilepsyFAERS: 3US FAERS
22CryingFAERS: 3US FAERS
23Drug effect incompleteFAERS: 3US FAERS
24DysgeusiaFAERS: 3US FAERS
25Feeling abnormalFAERS: 3OFFSIDES
US FAERS
26LymphadenopathyFAERS: 3US FAERS
27MalaiseFAERS: 3US FAERS
28Oropharyngeal painFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
29PainFAERS: 3US FAERS
30PseudolymphomaFAERS: 3US FAERS
31AgitationFAERS: 2SIDER
US FAERS
32Back PainFAERS: 2US FAERS
33Drug level changedFAERS: 2US FAERS
34Lupus-like syndromeFAERS: 2US FAERS
35Memory impairmentFAERS: 2US FAERS
36Mood swingsFAERS: 2US FAERS
37NervousnessFAERS: 2US FAERS
38Oral painFAERS: 2US FAERS
39PancytopeniaFAERS: 2SIDER
US FAERS
40ParanoiaFAERS: 2SIDER
US FAERS
41Poor quality product administeredFAERS: 2US FAERS
42Product physical issueFAERS: 2US FAERS
43Product quality issueFAERS: 2US FAERS
44Product size issueFAERS: 2US FAERS
45Product storage errorFAERS: 2US FAERS
46Product use complaintFAERS: 2US FAERS
47PruritusFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
48Reaction to excipientFAERS: 2US FAERS
49Restless Legs SyndromeFAERS: 2US FAERS
50SomnolenceFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
51ThrombocytopeniaFAERS: 2
Canada Vigilance: 1		623072CTD
Canada Vigilance
US FAERS
52Toxicity to various agentsFAERS: 2US FAERS
53TremorFAERS: 21350061CTD
US FAERS
54UrticariaFAERS: 2SIDER
US FAERS
55Weight decreasedFAERS: 2SIDER
US FAERS
56Wrong technique in drug usage processFAERS: 2US FAERS
57AchlorhydriaFAERS: 1US FAERS
58Alanine Aminotransferase IncreasedFAERS: 1US FAERS
59AlopeciaFAERS: 1US FAERS
60Amino acid level increasedFAERS: 1US FAERS
61AngioedemaFAERS: 1OFFSIDES
US FAERS
62Apparent deathFAERS: 1US FAERS
63AscitesFAERS: 1US FAERS
64Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
65Barbiturates positiveFAERS: 1US FAERS
66Bile output decreasedFAERS: 1US FAERS
67BlindnessFAERS: 1US FAERS
68Blood alkaline phosphatase increasedFAERS: 1US FAERS
69Body height below normalFAERS: 1US FAERS
70Central nervous system lesionFAERS: 1US FAERS
71CheilitisFAERS: 1US FAERS
72ChokingFAERS: 1US FAERS
73Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
74Complement factor decreasedFAERS: 1US FAERS
75Complex partial seizuresFAERS: 1OFFSIDES
US FAERS
76CystitisFAERS: 1US FAERS
77DisorientationFAERS: 1US FAERS
78Dissociative AmnesiaFAERS: 1US FAERS
79Drug level above therapeuticFAERS: 1US FAERS
80Drug prescribing errorFAERS: 1US FAERS
81Drug screen positiveFAERS: 1US FAERS
82Electroencephalogram abnormalFAERS: 1US FAERS
83Emotional disorderFAERS: 1US FAERS
84Emotional distressFAERS: 1US FAERS
85EnuresisFAERS: 1US FAERS
86ErythemaFAERS: 1US FAERS
87Euphoric moodFAERS: 1SIDER
US FAERS
88Eye irritationFAERS: 1US FAERS
89Failure to ThriveFAERS: 1OFFSIDES
US FAERS
90GastritisFAERS: 1US FAERS
91Growth retardationFAERS: 1US FAERS
92HypersensitivityFAERS: 1SIDER
US FAERS
93Impaired driving abilityFAERS: 1OFFSIDES
US FAERS
94Irritable Bowel SyndromeFAERS: 1US FAERS
95Joint sprainFAERS: 1US FAERS
96LethargyFAERS: 114978727CTD
OFFSIDES
SIDER
US FAERS
97Ligament ruptureFAERS: 1US FAERS
98Livedo ReticularisFAERS: 1US FAERS
99LymphopeniaFAERS: 19776542CTD
US FAERS
100Middle insomniaFAERS: 1US FAERS
101MyalgiaFAERS: 1US FAERS
102Myoclonic EpilepsyFAERS: 1US FAERS
103MyopiaFAERS: 1SIDER
US FAERS
104No adverse eventFAERS: 1US FAERS
105OverdoseFAERS: 1US FAERS
106Patient uncooperativeFAERS: 1US FAERS
107PericarditisFAERS: 1US FAERS
108PetechiaeFAERS: 1US FAERS
109PleurisyFAERS: 1US FAERS
110PoisoningFAERS: 1US FAERS
111PolyserositisFAERS: 1US FAERS
112Pressure of speechFAERS: 1OFFSIDES
US FAERS
113Product contaminationFAERS: 1US FAERS
114Product solubility abnormalFAERS: 1US FAERS
115Pulmonary EmbolismFAERS: 1US FAERS
116Reaction to drug excipientsFAERS: 1US FAERS
117RetchingFAERS: 1US FAERS
118Skin lacerationFAERS: 1US FAERS
119SluggishnessFAERS: 1US FAERS
120StaringFAERS: 1US FAERS
121Therapeutic response changedFAERS: 1US FAERS
122Therapeutic response unexpected with drug substitutionFAERS: 1US FAERS
123Therapy non-responderFAERS: 1US FAERS
124Tooth ExtractionFAERS: 1US FAERS
125Tooth LossFAERS: 1US FAERS
126Toxic Epidermal NecrolysisFAERS: 1US FAERS
127White blood cell count decreasedFAERS: 1US FAERS
128jaundiceFAERS: 1US FAERS
129Abdominal wall cystOFFSIDES
130AgranulocytosisSIDER
131Akathisia, Drug-Induced645680CTD
132Ammonia increasedOFFSIDES
133AnhidrosisOFFSIDES
134Anorexia623072CTD
SIDER
135ApathyOFFSIDES
136AtaxiaCanada Vigilance: 1Canada Vigilance
SIDER
137AutomatismOFFSIDES
138BlepharospasmOFFSIDES
139Blood and lymphatic system disordersSIDER
140BradycardiaOFFSIDES
141Brain Diseases25111975CTD
142Brain stem syndromeOFFSIDES
143Carnitine decreasedOFFSIDES
144CausalgiaOFFSIDES
145Cerebral artery stenosisOFFSIDES
146Chemical and Drug Induced Liver Injury25111975CTD
147Complicated fractureOFFSIDES
148Congenital heart diseaseOFFSIDES
149Depressed Level of ConsciousnessCanada Vigilance: 1Canada Vigilance
OFFSIDES
150DermatitisSIDER
151Disturbance in sexual arousalSIDER
152DrowsinessSIDER
153Drug addictOFFSIDES
154Dyskinesia, Drug-Induced6811702CTD
155Edema25111975CTD
156Educational problemOFFSIDES
157EosinophiliaSIDER
158Epilepsies, Partial3922381CTD
159Erythema MultiformeSIDER
160Fever8842769CTD
161FormicationOFFSIDES
162Gastrointestinal PainSIDER
163Gingival HypertrophySIDER
164Hematuria9776542CTD
165HepatotoxicityOFFSIDES
166HerniaOFFSIDES
167HiccoughOFFSIDES
168HirsutismSIDER
169HydronephrosisOFFSIDES
170Hyperalgesia15082137CTD
171HyperkinesiaSIDER
172HypospadiasOFFSIDES
173HypoxiaOFFSIDES
174Impaired work abilityOFFSIDES
175Inappropriate affectOFFSIDES
176Incorrect dose administeredOFFSIDES
177Joint injuryOFFSIDES
178Kidney Diseases8842769
9776542		CTD
179Lactose IntoleranceOFFSIDES
180LeukopeniaSIDER
181Liver diseases6847455CTD
182Lupus Erythematosus, Systemic9776542CTD
183MacroglossiaOFFSIDES
184MalnutritionSIDER
185Memory Disorders26420483CTD
186Microscopic hematuriaSIDER
187Muscle necrosisOFFSIDES
188Nephrotic SyndromeCanada Vigilance: 1623072CTD
Canada Vigilance
189Nerve Degeneration12192617CTD
190Nervous tensionOFFSIDES
191Oculocephalogyric reflex absentOFFSIDES
192OsteolysisOFFSIDES
193OsteopeniaOFFSIDES
194OsteoporosisOFFSIDES
195Personality Disorders9498910CTD
196PhimosisOFFSIDES
197PlagiocephalyOFFSIDES
198Pre-EclampsiaOFFSIDES
199Prenatal Exposure Delayed Effects9498910CTD
200PriapismOFFSIDES
201Proteinuria623072CTD
202Pyloric StenosisOFFSIDES
203Rash erythematousSIDER
204Respiratory DepressionCanada Vigilance: 1Canada Vigilance
205Seizures

View details

779804
841172
1970362
2507307
2978064
3137016
3607518
4414729
5355257
8469708
11738929
15475178
 		CTD
206Stent occlusionOFFSIDES
207Stevens-Johnson Syndrome25811541CTD
SIDER
208StridorOFFSIDES
209Thoracic vertebral fractureOFFSIDES
210Upset stomachSIDER
211Urine flow decreasedOFFSIDES
212nervous system disorderSIDER
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