MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Neurogenic Bowel

(UMLS:C0695242)

Definition:: Loss or absence of normal intestinal function due to nerve damage or birth defects. It is characterized by the inability to control the elimination of stool from the body.
UMLS ID:: C0695242
MeSH ID:: D055496

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405.469.158.272.804

Synonym(s)

Neurogenic Bowel

BOWEL NEUROGENIC

Neurogenic bowel

bowel; neurogenic

neurogenic bowel

neurogenic; bowel

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Alendronate	FAERS: 4		US FAERS
2	Paroxetine	FAERS: 3		US FAERS
3	rofecoxib	FAERS: 3		OFFSIDES US FAERS
4	Dimethyl Fumarate	FAERS: 2		US FAERS
5	teriflunomide	FAERS: 2		US FAERS
6	4-Aminopyridine	FAERS: 1		US FAERS
7	Cisapride	FAERS: 1		US FAERS
8	Fingolimod Hydrochloride	FAERS: 1		US FAERS
9	Glatiramer Acetate	FAERS: 1		US FAERS
10	Itraconazole	FAERS: 1		US FAERS
11	Liraglutide	FAERS: 1		US FAERS
12	Mifepristone	FAERS: 1		US FAERS
13	Morphine	FAERS: 1		US FAERS
14	Paclitaxel	FAERS: 1		US FAERS
15	Paroxetine	FAERS: 1		US FAERS
16	Prasugrel Hydrochloride	FAERS: 1		US FAERS
17	Prepopik	FAERS: 1		US FAERS
18	Sertraline	FAERS: 1		US FAERS
19	Teriparatide	FAERS: 1		US FAERS
20	Testosterone	FAERS: 1		US FAERS
21	Valproic Acid	FAERS: 1		US FAERS
22	Zoledronic Acid	FAERS: 1		US FAERS
23	apremilast	FAERS: 1		US FAERS
24	betamethasone acetate phosphate	FAERS: 1		US FAERS
25	Alcohols			OFFSIDES
26	Anastrozole			OFFSIDES
27	Atropine			OFFSIDES
28	Bisacodyl			OFFSIDES
29	Bupropion			OFFSIDES
30	Chlorhexidine			OFFSIDES
31	Dioctyl Sulfosuccinic Acid			OFFSIDES
32	Ibuprofen			OFFSIDES
33	Letrozole			OFFSIDES
34	Methylphenidate			OFFSIDES
35	Naloxone			OFFSIDES
36	Nicotine			OFFSIDES
37	Pamidronate			OFFSIDES
38	Penicillin V			OFFSIDES
39	Pergolide			OFFSIDES
40	Phenytoin		2492459	CTD
41	Piperacillin, Tazobactam Drug Combination			OFFSIDES
42	Primidone		2492459	CTD
43	Rabeprazole			OFFSIDES
44	Simethicone			OFFSIDES
45	Thalidomide			OFFSIDES
46	Valproic Acid		2492459	CTD
47	chlorhexidine gluconate			OFFSIDES
48	dexamethasone acetate			OFFSIDES
49	metaxalone			OFFSIDES
50	trospium chloride			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Irritable Bowel Syndrome	49.2%
2	Colonic Pseudo-Obstruction	38.3%
3	Megacolon	36%
4	Colitis	32.4%
5	Cecal Diseases	28.5%
6	Ileal Diseases	28.5%
7	Intestinal Obstruction	28.5%
8	Intestinal Perforation	28.5%
9	Jejunal Diseases	28.5%
10	Pneumatosis Cystoides Intestinalis	28.5%
11	Rectal Diseases	28.5%
12	Cronkhite-Canada Syndrome	28.5%
13	Intestinal Polyposis	28.5%
14	Dysentery	27.3%
15	Enteritis	27.3%
16	Enterocolitis	27.3%
17	Inflammatory Bowel Diseases	27.3%
18	Proctocolitis	24.5%
19	Colorectal Neoplasms	22.7%
20	Esophageal Diseases	22.7%
21	Gastroenteritis	22.7%
22	Stomach Diseases	22.7%
23	Duodenal Obstruction	22.5%
24	Duodenitis	20.5%
25	Ileitis	20.5%
26	Erosive Duodenitis	20.5%
27	Intestinal Diseases, Parasitic	20.5%
28	Duodenogastric Reflux	19.5%
29	Peptic Ulcer	19.5%
30	Proctitis	19.5%
31	Zollinger-Ellison syndrome	19.1%
32	Mesenteric vascular insufficiency	18.7%
33	Intestinal Atresia	18.4%
34	Mesenteric Vascular Occlusion	18.4%
35	Intestinal Fistula	18.3%
36	Enterocutaneous Fistula	18.3%
37	Intestinal Neoplasms	18%
38	Fecal Incontinence	16.8%
39	Fecal Impaction	16.8%
40	Intussusception	16.8%
41	Ileus	16.8%
42	Meconium ileus	16.8%
43	Esophagitis	16.4%
44	Gastritis	16.4%
45	Crohn Disease	16%
46	Enterocolitis, Neutropenic	16%
47	Necrotizing Enterocolitis	16%
48	Colitis, Ischemic	16%
49	Sigmoid Neoplasms	15.5%
50	Gastrointestinal Neoplasms	15.3%
51	Biliary Tract Diseases	15.3%
52	Liver diseases	15.3%
53	Pancreatic Diseases	15.3%
54	Rectal Fistula	15.2%
55	Anal Fistula	15.2%
56	Gastrointestinal Hemorrhage	15.1%
57	Tuberculosis, Gastrointestinal	14.8%
58	Appendicitis	14.7%
59	Cecal Neoplasms	14.4%
60	Duodenal Neoplasms	14.4%
61	Colonic Neoplasms	13.7%
62	Pouchitis	13.5%
63	Duodenal Ulcer	12.2%
64	Peptic Ulcer Perforation	12.2%
65	Gastric ulcer	12.2%
66	Esophageal Stenosis	12.2%
67	Gastric Dilatation	12.2%
68	Gastric outlet obstruction	12.2%
69	Enterocolitis, Pseudomembranous	12%
70	pseudomembranous colitis	12%
71	Dysentery, Bacillary	12%
72	Adenomatous Polyposis Coli	11.8%
73	Hemorrhoids	11.6%
74	Stomach Neoplasms	11.5%
75	Afferent Loop Syndrome	11.4%
76	Celiac Disease	11.4%
77	Short Bowel Syndrome	11.4%
78	Sprue, Tropical	11.4%
79	Steatorrhea	11.4%
80	Rectocele	11.4%
81	Sprue	11.4%
82	Rectal Prolapse	11.2%
83	Anal Fissure	11.1%
84	Intestinal Pseudo-Obstruction	11.1%
85	Superior Mesenteric Artery Syndrome	11.1%
86	Anal Ulcer	11.1%
87	Esophageal and Gastric Varices	10.9%
88	Digestive System Neoplasms	10.2%
89	Esophageal Atresia	10%
90	Esophageal Neoplasms	9.6%
91	Appendiceal Neoplasms	9.5%
92	Rectal Neoplasms	9.5%
93	Anus Neoplasms	9.2%
94	Giardiasis	8.9%
95	Esophageal Perforation	8.8%
96	Barrett Esophagus	8.4%
97	Deglutition Disorders	8.4%
98	Achlorhydria	8.2%
99	Gastric Antral Vascular Ectasia	8.2%
100	Gastrointestinal Stromal Tumors	8.2%
101	Peptic Ulcer Hemorrhage	8.1%
102	Gastroparesis	8.1%
103	Liver neoplasms	7.7%
104	Pancreatic Fistula	7.6%
105	Bile Duct Diseases	7.6%
106	Cholelithiasis	7.6%
107	Chylous Ascites	7.6%
108	Fatty Liver	7.6%
109	Hepatitis	7.6%
110	Portal Hypertension	7.6%
111	Liver Cirrhosis	7.6%
112	Pancreatic Insufficiency	7.6%
113	Pancreatitis	7.6%
114	Pneumoperitoneum	7.6%
115	Focal Nodular Hyperplasia	7.6%
116	Hepatic Insufficiency	7.6%
117	Steatohepatitis	7.6%
118	Pruritus Ani	7.5%
119	Esophageal motility disorders	7.2%
120	Mallory-Weiss Syndrome	7.2%
121	Pyloric Stenosis	7.2%
122	Peutz-Jeghers Syndrome	6.9%
123	Lactose Intolerance	6.8%
124	Melena	6.2%
125	Peritoneal Neoplasms	6.1%
126	Hematemesis	6.1%
127	Cholecystolithiasis	5.5%
128	Liver Diseases, Parasitic	5.4%
129	Hepatic Veno-Occlusive Disease	5.1%
130	Pancreatic Cyst	5.1%
131	Peliosis Hepatis	5.1%
132	Hepatopulmonary Syndrome	5.1%
133	Pancreatic Neoplasm	5.1%
134	Anus, Imperforate	5%
135	Hemoperitoneum	5%
136	Hepatomegaly	5%
137	Mesenteric Panniculitis	5%
138	Panniculitis, Peritoneal	5%
139	Peritonitis	5%
140	Peritoneal Fibrosis	5%
141	Encapsulating Peritoneal Sclerosis	5%
142	Anorectal Malformations	5%
143	Cryptosporidiosis	5%
144	Biliary Fistula	5%
145	Gastric Fistula	5%
146	Hepatic Vein Thrombosis	4.9%
147	Liver Abscess	4.9%
148	Budd-Chiari Syndrome	4.9%
149	Bile Duct Neoplasms	4.9%
150	gallbladder neoplasm	4.9%
151	Biliary cirrhosis	4.9%
152	Diverticulitis	4.8%
153	Dumping Syndrome	4.8%
154	Esophageal Achalasia	4.8%
155	Choledochal Cyst	4.7%
156	Choledocholithiasis	4.3%
157	Cholangitis	4.1%
158	Cholecystitis	4.1%
159	Cholestasis	4.1%
160	Common Bile Duct Diseases	4.1%
161	Fatty Liver, Alcoholic	4.1%
162	Hepatitis, Alcoholic	4.1%
163	Hepatitis, Chronic	4.1%
164	Liver Cirrhosis, Alcoholic	4.1%
165	Liver Failure	4.1%
166	Pancreatitis, Chronic	4.1%
167	Non-alcoholic Fatty Liver Disease	4.1%
168	Chronic active hepatitis	4.1%
169	Chemical and Drug Induced Liver Injury	3.9%
170	Hepatorenal Syndrome	3.7%
171	Diverticulum	3.7%
172	Diverticulosis	3.7%
173	Hepatocellular Adenoma	3.3%
174	Cystic Fibrosis	3.1%
175	Porphyrias, Hepatic	3%
176	Congenital Hyperinsulinism	3%
177	Hepatitis, Animal	2.9%
178	Hepatitis, Viral, Human	2.9%
179	Liver Abscess, Amebic	2.8%
180	Liver Neoplasms, Experimental	2.8%
181	Liver Cirrhosis, Experimental	2.7%
182	Pancreatic Pseudocyst	2.7%
183	Pancreatitis, Alcoholic	2.7%
184	Laryngopharyngeal Reflux	2.5%
185	Cholestasis, Extrahepatic	2.4%
186	Biliary Dyskinesia	2.4%
187	Cholangitis, Sclerosing	2.4%
188	Liver Failure, Acute	2.4%
189	Acalculous Cholecystitis	2.4%
190	End Stage Liver Disease	2.4%
191	Fascioliasis	2.1%
192	Echinococcosis, Hepatic	2.1%
193	Chemical and Drug Induced Liver Injury, Chronic	2.1%
194	Reye Syndrome	2%
195	Carcinoma, Pancreatic Ductal	2%
196	Autoimmune hepatitis	1.7%
197	Nesidioblastosis	1.6%
198	Variegate Porphyria	1.6%
199	Acute intermittent porphyria	1.6%
200	Porphyria Cutanea Tarda	1.6%
201	Hepatitis B, Chronic	1.6%
202	Hepatitis C, Chronic	1.6%
203	Massive Hepatic Necrosis	1.6%
204	Emphysematous Cholecystitis	1.6%
205	Sphincter of Oddi Dysfunction	1.6%
206	CREST Syndrome	1.4%
207	insulinoma	1.4%
208	Gastrinoma	1.4%
209	Glucagonoma	1.4%
210	Zellweger Syndrome	1.3%
211	Hepatitis, Viral, Animal	1.3%
212	Hepatitis E	1.3%
213	Hepatitis B	1.2%
214	Hepatitis C	1.2%
215	Hepatitis A	1.2%
216	Hepatolenticular Degeneration	1.2%
217	Hepatic Encephalopathy	1.2%
218	Vipoma	1.2%
219	Rift Valley Fever	0.5%

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