MetaADEDB 2.0 @ LMMD
Droperidol
(RMEDXOLNCUSCGS-UHFFFAOYSA-N)
Structure
SMILES
Fc1ccc(cc1)C(=O)CCCN1CCC(=CC1)n1c(=O)[nH]c2c1cccc2
Type(s)
Approved; Vet_approved
ATC code(s)
N05AD08
Molecular Formula:
C22H22FN3O2
Molecular Weight:
379.427
Log P:
3.6163
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
58.1
CAS Number(s):
548-73-2
Synonym(s)
1.
Droperidol
2.
Dehydrobenzperidol
3.
Dehidrobenzperidol
4.
Droleptan
5.
Inapsine
External Link(s)
MeSHD004329
PubChem Compound3168
BindingDB50017705
ChEBI4717
CHEMBLCHEMBL1108
DrugBankDB00450
DrugCentral966
IUPHAR/BPS Guide to PHARMACOLOGY7172
KEGGdr:D00308
Therapeutic Target DatabaseD03CJL
ZINC19796080
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1RestlessnessFAERS: 8US FAERS
2AnxietyFAERS: 7
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
SIDER
US FAERS
3AgitationFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
4DystoniaFAERS: 4

View details

3415026
7933512
7990989
9557916
11075569
16338521
16387219
20169968
 		CTD
OFFSIDES
US FAERS
5Feeling abnormalFAERS: 4US FAERS
6Respiratory arrestFAERS: 3US FAERS
7Restless Legs SyndromeFAERS: 3US FAERS
8Sudden deathFAERS: 3OFFSIDES
SIDER
US FAERS
9TremorFAERS: 3
Canada Vigilance: 1		1130732CTD
Canada Vigilance
US FAERS
10Drug toxicityFAERS: 2US FAERS
11FatigueFAERS: 2US FAERS
12PalpitationsFAERS: 2SIDER
US FAERS
13Peripheral swellingFAERS: 2US FAERS
14Sinus bradycardiaFAERS: 2US FAERS
15TachycardiaFAERS: 2426993
434546
4562467		CTD
SIDER
US FAERS
16VomitingFAERS: 2

View details

1616115
2817476
3698040
6370028
7242608
12460844
12552051
16338521
 		CTD
US FAERS
17AkathisiaFAERS: 1SIDER
US FAERS
18AphasiaFAERS: 1US FAERS
19AtelectasisFAERS: 1OFFSIDES
US FAERS
20Atrial FibrillationFAERS: 1US FAERS
21Autonomic nervous system imbalanceFAERS: 1SIDER
US FAERS
22Back PainFAERS: 1US FAERS
23Blood magnesium abnormalFAERS: 1US FAERS
24Brain DeathFAERS: 1OFFSIDES
US FAERS
25BruxismFAERS: 1US FAERS
26Cardiac ArrestFAERS: 1SIDER
US FAERS
27CardiomegalyFAERS: 1US FAERS
28CatatoniaFAERS: 1OFFSIDES
US FAERS
29CyanosisFAERS: 1US FAERS
30DissociationFAERS: 1US FAERS
31Documented hypersensitivity to administered drugFAERS: 1US FAERS
32Drug ineffectiveFAERS: 1US FAERS
33Economic problemFAERS: 1OFFSIDES
US FAERS
34Emotional disorderFAERS: 1US FAERS
35EpilepsyFAERS: 1US FAERS
36ErythemaFAERS: 1US FAERS
37ExcitabilityFAERS: 1US FAERS
38ExcoriationFAERS: 1OFFSIDES
US FAERS
39Feeling jitteryFAERS: 1US FAERS
40FlushingFAERS: 1US FAERS
41MalaiseFAERS: 1US FAERS
42Muscle RigidityFAERS: 1

View details

1130732
5064016
5165426
5817964
11406684
 		CTD
SIDER
US FAERS
43Muscle tightnessFAERS: 1US FAERS
44Musculoskeletal PainFAERS: 1OFFSIDES
US FAERS
45Musculoskeletal stiffnessFAERS: 1OFFSIDES
US FAERS
46NauseaFAERS: 1

View details

4812365
6196992
6370028
7242608
12552051
16338521
 		CTD
OFFSIDES
US FAERS
47Neck PainFAERS: 1US FAERS
48Nerve injuryFAERS: 1US FAERS
49Neuroleptic Malignant SyndromeFAERS: 111406684CTD
OFFSIDES
SIDER
US FAERS
50OpisthotonusFAERS: 1US FAERS
51PainFAERS: 1

View details

4051164
7128786
7933512
12460844
16300977
 		CTD
OFFSIDES
US FAERS
52PleurisyFAERS: 1US FAERS
53Pulmonary congestionFAERS: 1US FAERS
54SomnolenceFAERS: 1SIDER
US FAERS
55Tardive DyskinesiaFAERS: 1SIDER
US FAERS
56Toxicologic test abnormalFAERS: 1US FAERS
57TrismusFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
58Ventricle ruptureFAERS: 1US FAERS
59Ventricular FibrillationFAERS: 1US FAERS
60Vital functions abnormalFAERS: 1US FAERS
61Actinic keratosisOFFSIDES
62Akathisia, Drug-Induced

View details

2817476
6123780
7933512
11075569
12552051
 		CTD
63Altered state of consciousnessSIDER
64AlveoloplastyOFFSIDES
65AnalgesiaOFFSIDES
66Anaphylactic shockSIDER
67Angioedema8155111
8599504		CTD
SIDER
68AnhedoniaOFFSIDES
69AnoxiaOFFSIDES
70Anoxic EncephalopathyOFFSIDES
71Anxiety Disorders

View details

3415026
4683937
7048838
12460844
12552051
15321332
 		CTD
72Apnea6196992CTD
OFFSIDES
73ArthropathyOFFSIDES
74AstheniaOFFSIDES
75Athetosis4812365CTD
76Atrial FlutterOFFSIDES
77Bacterial sepsisOFFSIDES
78Basal Ganglia Diseases

View details

2233626
3415026
7426261
7933512
10411778
12378031
16104540
 		CTD
79Basal cell carcinomaOFFSIDES
80BlastomycosisOFFSIDES
81BlepharospasmOFFSIDES
82Blood albumin decreasedOFFSIDES
83Blood creatinine increasedOFFSIDES
84Blood glucose decreasedOFFSIDES
85Blood testosterone decreasedOFFSIDES
86Bone density decreasedOFFSIDES
87Bone lesionOFFSIDES
88Bone painOFFSIDES
89Bradycardia5817964
16387219
22744888		CTD
90Bronchial FistulaOFFSIDES
91BronchospasmSIDER
92BursitisOFFSIDES
93Cancer PainOFFSIDES
94Cardiovascular Diseases3698040
14724874		CTD
95Catheter placementOFFSIDES
96Cerebral atrophyOFFSIDES
97Cervical cord compressionOFFSIDES
98ChillsSIDER
99ChylothoraxOFFSIDES
100Cognition Disorders6838742CTD
101Compression fractureOFFSIDES
102Confusion1267895
4683937		CTD
103ContractureOFFSIDES
104CryingOFFSIDES
105Cyst removalOFFSIDES
106Cytolytic hepatitisOFFSIDES
107DebridementOFFSIDES
108Delirium4713950CTD
109DemyelinationOFFSIDES
110Dental abscessOFFSIDES
111Dental cariesOFFSIDES
112Denture wearerOFFSIDES
113DermatitisSIDER
114DiabetesOFFSIDES
115Diplopia1130732CTD
116Disorders of Excessive Somnolence1267895
11406684
12552051		CTD
117DiverticulitisOFFSIDES
118DizzinessSIDER
119DrowsinessSIDER
120Dyskinesia, Drug-Induced1147302
3717542		CTD
121DyslaliaOFFSIDES
122DysphoniaCanada Vigilance: 1Canada Vigilance
123Dysthymic DisorderOFFSIDES
124Emotional distressOFFSIDES
125End-tidal CO2 increasedOFFSIDES
126EndocarditisOFFSIDES
127Endotracheal intubation complicationOFFSIDES
128Erectile dysfunctionOFFSIDES
129Feeling ColdOFFSIDES
130Feeling of body temperature changeOFFSIDES
131Fever11406684CTD
132FibromyalgiaOFFSIDES
133FormicationOFFSIDES
134GangreneOFFSIDES
135Gaze palsyOFFSIDES
136Genital erosionOFFSIDES
137GlossoptosisOFFSIDES
138GranulomaOFFSIDES
139Hallucinations4562467CTD
140Heart Block18323319CTD
141Histamine level increasedOFFSIDES
142Hyperacusis12552051CTD
143HypersensitivitySIDER
144HyperventilationOFFSIDES
145Hypoglossal Nerve DisorderOFFSIDES
146HypophagiaOFFSIDES
147HypotensionCanada Vigilance: 112460844CTD
SIDER
Canada Vigilance
148HypoxiaOFFSIDES
149Incorrect drug administration rateOFFSIDES
150Increased bronchial secretionOFFSIDES
151Infection in an immunocompromised hostOFFSIDES
152Intervertebral Disc DegenerationOFFSIDES
153Intervertebral disc disorderOFFSIDES
154Jaw lesion excisionOFFSIDES
155LacerationOFFSIDES
156Lactose IntoleranceOFFSIDES
157LaparotomyOFFSIDES
158LaryngospasmSIDER
159LethargyOFFSIDES
160Life expectancy shortenedOFFSIDES
161Long QT Syndrome

View details

1776799
15385011
15915019
16733113
16757186
18323319
18648229
20210726
 		CTD
162MeningiomaOFFSIDES
163Migraine Disorders12552051CTD
164Mucosal erosionOFFSIDES
165Multiple drug overdoseOFFSIDES
166Muscle Hypertonia12378031CTD
167Muscular DystrophyOFFSIDES
168Musculoskeletal discomfortOFFSIDES
169Myoclonus7027723CTD
170MyoglobinaemiaOFFSIDES
171NephrolithiasisOFFSIDES
172Oculogyric crisisOFFSIDES
SIDER
173Oculomucocutaneous syndromeOFFSIDES
174OliguriaOFFSIDES
175OphthalmoplegiaOFFSIDES
176Orthosis userOFFSIDES
177OsteomyelitisOFFSIDES
178Pain, Postoperative10411778CTD
179Pancreatic enzymes increasedOFFSIDES
180ParesisCanada Vigilance: 1Canada Vigilance
181Parkinsonian Disorders1130732CTD
182Pericardial effusionOFFSIDES
183Periodontal infectionOFFSIDES
184Personality Disorders16387219
20868907		CTD
185Photophobia12552051CTD
186Physical disabilityOFFSIDES
187Postoperative Complications

View details

717770
1267895
1616115
12173200
 		CTD
188Postoperative Nausea and Vomiting

View details

58198
3415026
7598243
9539593
9649989
11075569
12173200
12378031
12707137
15721732
20169968
 		CTD
189Primary sequestrumOFFSIDES
190Procedural vomitingOFFSIDES
191Product quality issueOFFSIDES
192Psychomotor Agitation3944073
12460844		CTD
193Psychotic Disorders15138973
15268653		CTD
194Pyogenic granulomaOFFSIDES
195Renal tubular necrosisOFFSIDES
196Respiratory Insufficiency5817964
12460844		CTD
197RhabdomyolysisOFFSIDES
198Risus sardonicusOFFSIDES
199Seizures9174307
12460844		CTD
200Senile dementiaOFFSIDES
201ShiveringSIDER
202ShockSIDER
203Sick Sinus SyndromeOFFSIDES
204Spinal Cord Diseases3674497CTD
205Spinal corpectomyOFFSIDES
206Spinal fusion surgeryOFFSIDES
207Stem cell transplantOFFSIDES
208Stenotrophomonas infectionOFFSIDES
209Subdural EffusionOFFSIDES
210SyncopeSIDER
211Systolic hypertensionOFFSIDES
212Tachycardia, Ventricular1167743CTD
213Therapy non-responderOFFSIDES
214Tooth ExtractionOFFSIDES
215Torsades de Pointes9681092
17122267
19291568		CTD
216UrticariaCanada Vigilance: 1Canada Vigilance
217Vascular bypass graftOFFSIDES
218Ventricular arrhythmiaSIDER
219Vertebral wedgingOFFSIDES
220bone marrow fibrosisOFFSIDES
221kyphosisOFFSIDES
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