Diabetic Ketoacidosis
(UMLS:C0011880)
- Definition:
- A life-threatening complication of diabetes mellitus, primarily of TYPE 1 DIABETES MELLITUS with severe INSULIN deficiency and extreme HYPERGLYCEMIA. It is characterized by KETOSIS; DEHYDRATION; and depressed consciousness leading to COMA.
- UMLS ID:
- C0011880
- MeSH ID:
- D016883
Classification 1:
- Nutritional and Metabolic Diseases
- MeSH Tree Number(s):
- C18.452.076.176.652.500|C18.452.394.750.535
Classification 2:
- Endocrine System Diseases
- MeSH Tree Number(s):
- C19.246.099.812
Synonym(s)
1.
Diabetic Ketoacidosis
2.
ACIDOSIS, DIABETIC
3.
DIABETIC ACIDOSIS
4.
DIABETIC KETOACIDOSIS
5.
DKA
6.
DKA - Diabetic ketoacidosis
7.
DKA - diabetic ketoacidosis
8.
Diabetes Mellitus with Ketoacidosis
9.
Diabetes mellitus with ketoacidosis
10.
Diabetes with ketoacidosis
11.
Diabetic acidosis
12.
Diabetic acidosis without coma
13.
Diabetic acidosis, NOS
14.
Diabetic keto-acidosis
15.
Diabetic ketoacidosis
16.
Diabetic ketosis
Associated Drug(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Canagliflozin | FAERS: 1784 Canada Vigilance: 68 | Canada Vigilance US FAERS | |
| 2 | empagliflozin | FAERS: 599 Canada Vigilance: 59 | Canada Vigilance US FAERS | |
| 3 | Quetiapine Fumarate | FAERS: 562 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 4 | 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol | FAERS: 501 Canada Vigilance: 22 | Canada Vigilance US FAERS | |
| 5 | Olanzapine | FAERS: 365 Canada Vigilance: 5 | 17632228 | CTD SIDER Canada Vigilance US FAERS |
| 6 | Insulin Glargine | FAERS: 124 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 7 | Risperidone | FAERS: 69 | SIDER US FAERS | |
| 8 | insulin glulisine | FAERS: 55 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 9 | Invokamet | FAERS: 50 | US FAERS | |
| 10 | Liraglutide | FAERS: 42 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 11 | Insulin Detemir | FAERS: 38 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | Glyxambi | FAERS: 37 | US FAERS | |
| 13 | Dapagliflozin and metformin hydrochloride | FAERS: 30 | US FAERS | |
| 14 | Aripiprazole | FAERS: 28 Canada Vigilance: 1 | Canada Vigilance SIDER US FAERS | |
| 15 | Insulin degludec | FAERS: 28 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 16 | Dexamethasone | FAERS: 27 | US FAERS | |
| 17 | Clozapine | FAERS: 25 Canada Vigilance: 3 | 11430560 | CTD Canada Vigilance US FAERS |
| 18 | Synjardy | FAERS: 25 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 19 | Insulin | FAERS: 24 | US FAERS | |
| 20 | Exenatide | FAERS: 21 | US FAERS | |
| 21 | Metformin | FAERS: 20 | US FAERS | |
| 22 | Everolimus | FAERS: 19 | US FAERS | |
| 23 | Metformin | FAERS: 18 | US FAERS | |
| 24 | Tacrolimus | FAERS: 17 | US FAERS | |
| 25 | Dimethyl Fumarate | FAERS: 16 | US FAERS | |
| 26 | Gabapentin | FAERS: 11 | SIDER US FAERS | |
| 27 | Quetiapine Fumarate | FAERS: 11 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 28 | Sitagliptin Phosphate | FAERS: 11 | US FAERS | |
| 29 | Mirtazapine | FAERS: 10 | US FAERS | |
| 30 | Esomeprazole | FAERS: 9 | US FAERS | |
| 31 | Varenicline | FAERS: 9 | US FAERS | |
| 32 | Carbamazepine | FAERS: 8 | US FAERS | |
| 33 | Gatifloxacin | FAERS: 8 | US FAERS | |
| 34 | insulin aspart, insulin aspart protamine drug combination 30:70 | FAERS: 8 | US FAERS | |
| 35 | Capecitabine | FAERS: 7 | US FAERS | |
| 36 | Prednisone | FAERS: 7 | US FAERS | |
| 37 | Pregabalin | FAERS: 7 | US FAERS | |
| 38 | Isotretinoin | FAERS: 6 | US FAERS | |
| 39 | semaglutide | FAERS: 6 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 40 | Prednisolone | FAERS: 5 | US FAERS | |
| 41 | teriflunomide | FAERS: 5 | US FAERS | |
| 42 | 5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-hydroxymethyl-6,8-dioxabicyclo(3.2.1)octane-2,3,4-triol | FAERS: 4 | US FAERS | |
| 43 | Albuterol | FAERS: 4 | US FAERS | |
| 44 | Atomoxetine Hydrochloride | FAERS: 4 | US FAERS | |
| 45 | Atorvastatin | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 46 | Docetaxel | FAERS: 4 | US FAERS | |
| 47 | Fingolimod Hydrochloride | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 48 | Imatinib Mesylate | FAERS: 4 | US FAERS | |
| 49 | Methadone | FAERS: 4 | US FAERS | |
| 50 | NuvaRing | FAERS: 4 | US FAERS | |
| 51 | Paliperidone Palmitate | FAERS: 4 | SIDER US FAERS | |
| 52 | 4-Aminopyridine | FAERS: 3 | US FAERS | |
| 53 | Amitriptyline | FAERS: 3 | US FAERS | |
| 54 | Asenapine | FAERS: 3 | US FAERS | |
| 55 | Bosentan | FAERS: 3 | US FAERS | |
| 56 | Clarithromycin | FAERS: 3 | US FAERS | |
| 57 | Droxidopa | FAERS: 3 | US FAERS | |
| 58 | Duloxetine Hydrochloride | FAERS: 3 | US FAERS | |
| 59 | Fentanyl | FAERS: 3 | US FAERS | |
| 60 | Lithium Carbonate | FAERS: 3 | US FAERS | |
| 61 | Oseltamivir | FAERS: 3 | US FAERS | |
| 62 | Pioglitazone | FAERS: 3 | US FAERS | |
| 63 | Sorafenib | FAERS: 3 | US FAERS | |
| 64 | Sulfamethoxazole | FAERS: 3 | US FAERS | |
| 65 | Vorinostat | FAERS: 3 | US FAERS | |
| 66 | ambrisentan | FAERS: 3 | US FAERS | |
| 67 | ceritinib | FAERS: 3 | US FAERS | |
| 68 | ledipasvir, sofosbuvir drug combination | FAERS: 3 | US FAERS | |
| 69 | rofecoxib | FAERS: 3 | US FAERS | |
| 70 | tofacitinib | FAERS: 3 | US FAERS | |
| 71 | treprostinil | FAERS: 3 | US FAERS | |
| 72 | ziprasidone | FAERS: 3 | US FAERS | |
| 73 | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | FAERS: 2 | US FAERS | |
| 74 | Acetaminophen | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 75 | Baclofen | FAERS: 2 | US FAERS | |
| 76 | Ciprofloxacin | FAERS: 2 | US FAERS | |
| 77 | Dabigatran | FAERS: 2 | US FAERS | |
| 78 | Deferasirox | FAERS: 2 | US FAERS | |
| 79 | Digoxin | FAERS: 2 | US FAERS | |
| 80 | Diltiazem | FAERS: 2 | US FAERS | |
| 81 | Diltiazem | FAERS: 2 | US FAERS | |
| 82 | Fluoxetine | FAERS: 2 | US FAERS | |
| 83 | Insulin Lispro | FAERS: 2 | US FAERS | |
| 84 | Ivermectin | FAERS: 2 | US FAERS | |
| 85 | Lamotrigine | FAERS: 2 | US FAERS | |
| 86 | Linagliptin | FAERS: 2 | US FAERS | |
| 87 | Linezolid | FAERS: 2 | US FAERS | |
| 88 | Lisinopril | FAERS: 2 | US FAERS | |
| 89 | Medroxyprogesterone Acetate | FAERS: 2 | US FAERS | |
| 90 | Naltrexone | FAERS: 2 | US FAERS | |
| 91 | Niacin | FAERS: 2 | US FAERS | |
| 92 | Oseltamivir | FAERS: 2 | US FAERS | |
| 93 | Paroxetine | FAERS: 2 | US FAERS | |
| 94 | Rivaroxaban | FAERS: 2 | US FAERS | |
| 95 | Rosiglitazone | FAERS: 2 | US FAERS | |
| 96 | Simvastatin | FAERS: 2 | US FAERS | |
| 97 | Sodium picosulfate | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 98 | Thyroxine | FAERS: 2 | US FAERS | |
| 99 | Valproic Acid | FAERS: 2 | US FAERS | |
| 100 | Vilazodone Hydrochloride | FAERS: 2 | US FAERS | |
| 101 | betamethasone dipropionate, calcipotriol drug combination | FAERS: 2 | US FAERS | |
| 102 | etonogestrel | FAERS: 2 | US FAERS | |
| 103 | paricalcitol | FAERS: 2 | US FAERS | |
| 104 | pramlintide | FAERS: 2 | US FAERS | |
| 105 | reviparin | FAERS: 2 | US FAERS | |
| 106 | 17 alpha-Hydroxyprogesterone Caproate | FAERS: 1 | US FAERS | |
| 107 | 2-[(E)-[1-(2-Amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid;(2S)-2,6-diaminohexanoic acid | FAERS: 1 | US FAERS | |
| 108 | 4-hydroxybutyric acid | FAERS: 1 | US FAERS | |
| 109 | Acyclovir | FAERS: 1 | US FAERS | |
| 110 | Adrenocorticotropic Hormone | FAERS: 1 | US FAERS | |
| 111 | Afatinib | FAERS: 1 | US FAERS | |
| 112 | Albuterol | FAERS: 1 | US FAERS | |
| 113 | Amiodarone | FAERS: 1 | US FAERS | |
| 114 | Amoxicillin-Potassium Clavulanate Combination | FAERS: 1 | US FAERS | |
| 115 | Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination | FAERS: 1 | US FAERS | |
| 116 | BMS201038 | FAERS: 1 | US FAERS | |
| 117 | Betamethasone | FAERS: 1 | US FAERS | |
| 118 | Cabozantinib S-malate | FAERS: 1 | US FAERS | |
| 119 | Caffeine | FAERS: 1 | US FAERS | |
| 120 | Celecoxib | FAERS: 1 | US FAERS | |
| 121 | Cyclosporine | FAERS: 1 | US FAERS | |
| 122 | Dabigatran | FAERS: 1 | US FAERS | |
| 123 | Dapagliflozin propanediol | FAERS: 1 | US FAERS | |
| 124 | Dapsone | FAERS: 1 | US FAERS | |
| 125 | Dasatinib | FAERS: 1 | US FAERS | |
| 126 | Desipramine | FAERS: 1 | US FAERS | |
| 127 | Dipyrone | FAERS: 1 | US FAERS | |
| 128 | Dronabinol | FAERS: 1 | US FAERS | |
| 129 | Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination | FAERS: 1 | US FAERS | |
| 130 | Epoprostenol | FAERS: 1 | US FAERS | |
| 131 | Finasteride | FAERS: 1 | US FAERS | |
| 132 | Gefitinib | FAERS: 1 | US FAERS | |
| 133 | Glatiramer Acetate | FAERS: 1 | US FAERS | |
| 134 | Glipizide | FAERS: 1 | US FAERS | |
| 135 | Glyburide | FAERS: 1 | US FAERS | |
| 136 | Goserelin | FAERS: 1 | US FAERS | |
| 137 | Hydrochlorothiazide | FAERS: 1 | US FAERS | |
| 138 | Hydrocortisone | FAERS: 1 | US FAERS | |
| 139 | Insulin, Isophane | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 140 | Irinotecan | FAERS: 1 | US FAERS | |
| 141 | Kombiglyze XR | FAERS: 1 | US FAERS | |
| 142 | LCZ 696 | FAERS: 1 | US FAERS | |
| 143 | Labetalol | FAERS: 1 | US FAERS | |
| 144 | Lenalidomide | FAERS: 1 | US FAERS | |
| 145 | Levetiracetam | FAERS: 1 | US FAERS | |
| 146 | Levofloxacin | FAERS: 1 | US FAERS | |
| 147 | Lisdexamfetamine Dimesylate | FAERS: 1 | US FAERS | |
| 148 | Lorazepam | FAERS: 1 | US FAERS | |
| 149 | Lurasidone Hydrochloride | FAERS: 1 | US FAERS | |
| 150 | Methylprednisolone Acetate | FAERS: 1 | US FAERS | |
| 151 | Methylprednisolone Hemisuccinate | FAERS: 1 | US FAERS | |
| 152 | Methylprednisolone Hemisuccinate | FAERS: 1 | US FAERS | |
| 153 | Methylprednisolone | FAERS: 1 | US FAERS | |
| 154 | Metoclopramide | FAERS: 1 | US FAERS | |
| 155 | Morphine | FAERS: 1 | US FAERS | |
| 156 | Mycophenolic Acid | FAERS: 1 | US FAERS | |
| 157 | NVP-BYL719 | FAERS: 1 | US FAERS | |
| 158 | Octreotide | FAERS: 1 | US FAERS | |
| 159 | Octreotide | FAERS: 1 | US FAERS | |
| 160 | Paclitaxel | FAERS: 1 | US FAERS | |
| 161 | Paliperidone Palmitate | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 162 | Pamidronate | FAERS: 1 | US FAERS | |
| 163 | Pemetrexed | FAERS: 1 | US FAERS | |
| 164 | Perindopril | FAERS: 1 | US FAERS | |
| 165 | Qtern | FAERS: 1 | US FAERS | |
| 166 | Ranolazine | FAERS: 1 | US FAERS | |
| 167 | Ribavirin | FAERS: 1 | US FAERS | |
| 168 | Rivastigmine | FAERS: 1 | US FAERS | |
| 169 | Rosiglitazone | FAERS: 1 | US FAERS | |
| 170 | Rosuvastatin Calcium | FAERS: 1 | US FAERS | |
| 171 | Sirolimus | FAERS: 1 | US FAERS | |
| 172 | Sodium Chloride | FAERS: 1 | US FAERS | |
| 173 | Telmisartan | FAERS: 1 | US FAERS | |
| 174 | Temozolomide | FAERS: 1 | US FAERS | |
| 175 | Terazosin | FAERS: 1 | US FAERS | |
| 176 | Teriparatide | FAERS: 1 | US FAERS | |
| 177 | Thalidomide | FAERS: 1 | US FAERS | |
| 178 | Theophylline | FAERS: 1 | US FAERS | |
| 179 | Triamcinolone Acetonide | FAERS: 1 | US FAERS | |
| 180 | Triumeq | FAERS: 1 | US FAERS | |
| 181 | Valacyclovir | FAERS: 1 | US FAERS | |
| 182 | Valproic Acid | FAERS: 1 | US FAERS | |
| 183 | Vemurafenib | FAERS: 1 | US FAERS | |
| 184 | Verapamil | FAERS: 1 | US FAERS | |
| 185 | Verapamil | FAERS: 1 | US FAERS | |
| 186 | Viekira Pak | FAERS: 1 | US FAERS | |
| 187 | Warfarin | FAERS: 1 | US FAERS | |
| 188 | aliskiren | FAERS: 1 | US FAERS | |
| 189 | amitriptyline, chlordiazepoxide drug combination | FAERS: 1 | US FAERS | |
| 190 | brexpiprazole | FAERS: 1 | US FAERS | |
| 191 | caffeine citrate | FAERS: 1 | US FAERS | |
| 192 | desloratadine | FAERS: 1 | US FAERS | |
| 193 | dexamethasone 21-phosphate | FAERS: 1 | US FAERS | |
| 194 | difluprednate | FAERS: 1 | US FAERS | |
| 195 | dolutegravir | FAERS: 1 | US FAERS | |
| 196 | drospirenone and ethinyl estradiol combination | FAERS: 1 | US FAERS | |
| 197 | efavirenz | FAERS: 1 | US FAERS | |
| 198 | entecavir | FAERS: 1 | US FAERS | |
| 199 | eribulin | FAERS: 1 | US FAERS | |
| 200 | gadobutrol | FAERS: 1 | US FAERS | |
| 201 | glimepiride | FAERS: 1 | US FAERS | |
| 202 | icatibant | FAERS: 1 | US FAERS | |
| 203 | ivacaftor | FAERS: 1 | US FAERS | |
| 204 | lanreotide | FAERS: 1 | US FAERS | |
| 205 | lumacaftor, ivacaftor drug combination | FAERS: 1 | US FAERS | |
| 206 | macitentan | FAERS: 1 | US FAERS | |
| 207 | niraparib | FAERS: 1 | US FAERS | |
| 208 | obeticholic acid | FAERS: 1 | US FAERS | |
| 209 | patiromer | FAERS: 1 | US FAERS | |
| 210 | pomalidomide | FAERS: 1 | US FAERS | |
| 211 | sapropterin | FAERS: 1 | US FAERS | |
| 212 | venetoclax | FAERS: 1 | US FAERS | |
| 213 | ziprasidone | FAERS: 1 | US FAERS | |
| 214 | Clofibrate | 416322 | CTD | |
| 215 | Diazoxide | SIDER | ||
| 216 | Fluoxetine | SIDER | ||
| 217 | Ondansetron | 19490041 | CTD | |
| 218 | Potassium | 11430560 | CTD | |
| 219 | Somatuline Autogel | Canada Vigilance: 1 | Canada Vigilance | |
| 220 | Tolvaptan | SIDER |
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