MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Talipes

(UMLS:C1301937)

Definition:: Deformity in which the foot is misaligned with respect to the TALUS in the ANKLE JOINT. While mostly congenital, as in CLUBFOOT, acquired deformities are included. Acquired talipedes are often associated with other foot deformities such as SYNDACTYLY and POLYDACTYLY.
UMLS ID:: C1301937
MeSH ID:: D000070558

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.330.488.655|C05.330.495.681|C05.660.585.512.380.813

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.621.585.512.500.681

Synonym(s)

Talipes

Talipes, NOS

Talipes, unspecified

feet talipes

talipes

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Paroxetine	FAERS: 323 Canada Vigilance: 3	Canada Vigilance OFFSIDES US FAERS
2	Fluoxetine	FAERS: 225	US FAERS
3	Sertraline	FAERS: 67	US FAERS
4	Valproic Acid	FAERS: 59	US FAERS
5	Citalopram	FAERS: 34	US FAERS
6	Lamotrigine	FAERS: 32	OFFSIDES US FAERS
7	Ondansetron	FAERS: 32	US FAERS
8	Citalopram	FAERS: 27 Canada Vigilance: 2	Canada Vigilance US FAERS
9	Valproic Acid	FAERS: 23	US FAERS
10	Paroxetine	FAERS: 21 Canada Vigilance: 6	Canada Vigilance US FAERS
11	Venlafaxine Hydrochloride	FAERS: 17 Canada Vigilance: 2	Canada Vigilance US FAERS
12	Methotrexate	FAERS: 16	US FAERS
13	Valproic Acid	FAERS: 15	US FAERS
14	Citalopram	FAERS: 12	US FAERS
15	Levetiracetam	FAERS: 12	US FAERS
16	Fluoxetine	FAERS: 11	US FAERS
17	Carbamazepine	FAERS: 10	US FAERS
18	Topiramate	FAERS: 10	US FAERS
19	Olanzapine	FAERS: 7	OFFSIDES US FAERS
20	Fingolimod Hydrochloride	FAERS: 5 Canada Vigilance: 1	Canada Vigilance US FAERS
21	Norgestrel	FAERS: 5	US FAERS
22	Isotretinoin	FAERS: 4	US FAERS
23	Risperidone	FAERS: 4	OFFSIDES US FAERS
24	Telmisartan	FAERS: 4	US FAERS
25	17 alpha-Hydroxyprogesterone Caproate	FAERS: 3	US FAERS
26	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride	FAERS: 3	OFFSIDES US FAERS
27	Cabergoline	FAERS: 3	OFFSIDES US FAERS
28	Dasatinib	FAERS: 3	US FAERS
29	Enalapril	FAERS: 3	US FAERS
30	Finasteride	FAERS: 3	US FAERS
31	Lithium	FAERS: 3	US FAERS
32	Metformin	FAERS: 3	US FAERS
33	Ofloxacin	FAERS: 3	US FAERS
34	Saquinavir	FAERS: 3	US FAERS
35	Acetaminophen	FAERS: 2	US FAERS
36	Buprenorphine	FAERS: 2	OFFSIDES US FAERS
37	Colchicine	FAERS: 2	US FAERS
38	Duloxetine Hydrochloride	FAERS: 2	US FAERS
39	Duloxetine Hydrochloride	FAERS: 2 Canada Vigilance: 1	Canada Vigilance US FAERS
40	Dutasteride	FAERS: 2	OFFSIDES US FAERS
41	Emtricitabine, Rilpivirine, Tenofovir Drug Combination	FAERS: 2	US FAERS
42	Ergotamine	FAERS: 2	US FAERS
43	Fondaparinux	FAERS: 2	US FAERS
44	Glatiramer Acetate	FAERS: 2	OFFSIDES US FAERS
45	Haloperidol	FAERS: 2	US FAERS
46	Ibuprofen	FAERS: 2	US FAERS
47	Lithium Carbonate	FAERS: 2 Canada Vigilance: 1	Canada Vigilance US FAERS
48	Mebendazole	FAERS: 2	US FAERS
49	Medroxyprogesterone Acetate	FAERS: 2	US FAERS
50	Metformin	FAERS: 2	US FAERS
51	Modafinil	FAERS: 2	US FAERS
52	Ranitidine	FAERS: 2	US FAERS
53	Sertraline	FAERS: 2	US FAERS
54	Warfarin	FAERS: 2	US FAERS
55	Zolpidem	FAERS: 2	US FAERS
56	candesartan	FAERS: 2	US FAERS
57	carbidopa, levodopa drug combination	FAERS: 2	US FAERS
58	efavirenz	FAERS: 2	OFFSIDES US FAERS
59	montelukast	FAERS: 2	US FAERS
60	2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol	FAERS: 1	US FAERS
61	Acitretin	FAERS: 1	OFFSIDES US FAERS
62	Amitriptyline	FAERS: 1	US FAERS
63	Amlodipine	FAERS: 1	US FAERS
64	Atorvastatin	FAERS: 1	US FAERS
65	Azathioprine	FAERS: 1	US FAERS
66	Azelaic acid	FAERS: 1	US FAERS
67	Baclofen	FAERS: 1	US FAERS
68	Betamethasone	FAERS: 1	US FAERS
69	Cetirizine	FAERS: 1	US FAERS
70	Cetirizine	FAERS: 1	US FAERS
71	Citalopram	FAERS: 1 Canada Vigilance: 2	Canada Vigilance US FAERS
72	Clomiphene	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
73	Desogestrel	FAERS: 1	US FAERS
74	Dinoprostone	FAERS: 1	US FAERS
75	Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination	FAERS: 1	US FAERS
76	Ethylene Glycol	FAERS: 1	US FAERS
77	Fluticasone	FAERS: 1	US FAERS
78	Hydroxychloroquine	FAERS: 1	US FAERS
79	Imipramine	FAERS: 1	US FAERS
80	Ivermectin	FAERS: 1	US FAERS
81	Leflunomide	FAERS: 1	US FAERS
82	Letrozole	FAERS: 1	US FAERS
83	Losartan	FAERS: 1	US FAERS
84	Mefloquine	FAERS: 1	US FAERS
85	Mesalamine	FAERS: 1	US FAERS
86	Methimazole	FAERS: 1	US FAERS
87	Methotrexate	FAERS: 1	US FAERS
88	Metoclopramide	FAERS: 1	US FAERS
89	Misoprostol	FAERS: 1	US FAERS
90	Mycophenolic Acid	FAERS: 1	US FAERS
91	Naltrexone	FAERS: 1	US FAERS
92	NuvaRing	FAERS: 1	US FAERS
93	Pamidronate	FAERS: 1	US FAERS
94	Penicillamine	FAERS: 1	US FAERS
95	Phenytoin	FAERS: 1	US FAERS
96	Quetiapine Fumarate	FAERS: 1	US FAERS
97	Quetiapine Fumarate	FAERS: 1	US FAERS
98	Simvastatin	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
99	Sulfasalazine	FAERS: 1	US FAERS
100	Tenofovir	FAERS: 1	OFFSIDES US FAERS
101	Thyroxine	FAERS: 1	US FAERS
102	Tinzaparin	FAERS: 1	US FAERS
103	Tretinoin	FAERS: 1	US FAERS
104	Valacyclovir	FAERS: 1	US FAERS
105	Zanamivir	FAERS: 1	US FAERS
106	Zidovudine	FAERS: 1	OFFSIDES US FAERS
107	Zolpidem	FAERS: 1	US FAERS
108	Zonisamide	FAERS: 1	US FAERS
109	levocetirizine	FAERS: 1	US FAERS
110	montelukast	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
111	norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination	FAERS: 1	US FAERS
112	pitavastatin	FAERS: 1	US FAERS
113	rofecoxib	FAERS: 1	US FAERS
114	Acetazolamide		OFFSIDES
115	Ambroxol		OFFSIDES
116	Atorvastatin	Canada Vigilance: 1	Canada Vigilance
117	Beclomethasone		OFFSIDES
118	Beclomethasone		OFFSIDES
119	Biperiden		OFFSIDES
120	Brimonidine Tartrate		OFFSIDES
121	Cephalexin		OFFSIDES
122	Clobazam		OFFSIDES
123	Clomiphene		SIDER
124	Clorazepate Dipotassium		OFFSIDES
125	Codeine		OFFSIDES
126	Cromolyn Sodium		OFFSIDES
127	Cromolyn Sodium		OFFSIDES
128	Diazepam		OFFSIDES
129	Fluconazole	Canada Vigilance: 1	Canada Vigilance
130	Fluorouracil		OFFSIDES
131	Fluticasone		OFFSIDES
132	Glucovance		OFFSIDES
133	Hydromorphone		OFFSIDES
134	Imipramine		OFFSIDES
135	Ketoconazole		OFFSIDES
136	Medroxyprogesterone		SIDER
137	Meperidine		OFFSIDES
138	Mianserin		OFFSIDES
139	Mometasone Furoate		OFFSIDES
140	Nelfinavir		OFFSIDES
141	Nevirapine		OFFSIDES
142	Nitrofurantoin		OFFSIDES
143	Nitrous Oxide		OFFSIDES
144	Nizatidine		OFFSIDES
145	Norethindrone Acetate		OFFSIDES
146	Nortriptyline		OFFSIDES
147	Oxymetazoline		OFFSIDES
148	Phenazopyridine		OFFSIDES
149	Prazosin		OFFSIDES
150	Pyridostigmine Bromide		OFFSIDES
151	Riluzole		OFFSIDES SIDER
152	Sodium Citrate		OFFSIDES
153	Tenofovir		OFFSIDES
154	Triamcinolone		OFFSIDES
155	Trihexyphenidyl		OFFSIDES
156	Ursodeoxycholic Acid		OFFSIDES
157	Vigabatrin		SIDER
158	Vitamin B 12		OFFSIDES
159	abacavir, lamivudine drug combination		OFFSIDES
160	alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination		OFFSIDES
161	cyamemazine		OFFSIDES
162	dipropylacetamide		OFFSIDES
163	etizolam		OFFSIDES
164	ferric citrate		OFFSIDES
165	ferrous fumarate		OFFSIDES
166	fosamprenavir		OFFSIDES
167	gadodiamide		OFFSIDES
168	lamivudine, zidovudine drug combination		OFFSIDES
169	propiomazine		OFFSIDES
170	sennoside A&B		OFFSIDES
171	tegaserod		OFFSIDES
172	tegaserod		OFFSIDES
173	urapidil		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Arthrogryposis	31.3%
2	Bunion	27.7%
3	Syndactyly	26.9%
4	Pectus carinatum	25.3%
5	Pectus excavatum	24.5%
6	Amelia	24%
7	Arachnodactyly	24%
8	Ectromelia	24%
9	Hemimelia	24%
10	Phocomelia	24%
11	Sirenomelia	24%
12	Polydactyly	24%
13	Brachydactyly	24%
14	Upper Extremity Deformities, Congenital	24%
15	Klippel-Feil Syndrome	23%
16	Synostosis	23%
17	Craniofacial Abnormalities	22.8%
18	Craniosynostosis	19.7%
19	Brachycephaly	19.7%
20	Acrocephalosyndactylia	19.6%
21	Gastroschisis	19.4%
22	Bone Diseases	19.4%
23	Fasciitis	19.4%
24	Arthropathy	19.4%
25	Platybasia	18.5%
26	Contracture	18.4%
27	Osteoarthropathy, Secondary Hypertrophic	18.4%
28	Fasciitis, Plantar	18.4%
29	Poland Syndrome	17.4%
30	Jaw Diseases	16.6%
31	Cartilage Diseases	16.3%
32	Foot Diseases	16.3%
33	Myopathy	16.3%
34	Rheumatism	16.3%
35	Chondromalacia	16.3%
36	Fibromyalgia	15.8%
37	Osteochondritis	15.8%
38	Polymyalgia Rheumatica	15.8%
39	Metatarsalgia	15.7%
40	Craniofacial Dysostosis	14.8%
41	Gout	14.2%
42	Rubinstein-Taybi Syndrome	14.1%
43	Talipes	13.8%
44	Plagiocephaly	13.2%
45	Holoprosencephaly	13%
46	Ischemic contracture	12.9%
47	Temporomandibular Joint Disorders	12.9%
48	Maxillofacial Abnormalities	12.8%
49	Osteoarthritis, Spine	12.8%
50	Rheumatic Fever	12.7%
51	Laryngomalacia	12.1%
52	Jaw Abnormalities	11.9%
53	Nail-Patella Syndrome	11.5%
54	Hip Contracture	11.5%
55	Periarthritis	11.5%
56	Antley-Bixler Syndrome Phenotype	11.3%
57	Temporomandibular Joint Dysfunction Syndrome	11.3%
58	Rheumatoid Arthritis	11.3%
59	Juvenile arthritis	11.3%
60	Arthritis	10.9%
61	Bone Diseases, Developmental	10.9%
62	Bursitis	10.9%
63	Hyperostosis	10.9%
64	Joint Instability	10.9%
65	Myofascial Pain Syndromes	10.9%
66	Osteitis	10.9%
67	Osteitis Deformans	10.9%
68	Osteochondrosis	10.9%
69	Rhabdomyolysis	10.9%
70	Spinal Diseases	10.9%
71	Synovitis	10.9%
72	Joint laxity	10.9%
73	Polyarthritis	10.9%
74	Frozen shoulder	10.9%
75	Patellofemoral Pain Syndrome	10.9%
76	Microcephaly	10.7%
77	Macrocephaly	10.7%
78	Congenital clubfoot	10.2%
79	Vertical Talus	10.2%
80	Ankylosing spondylitis	10%
81	Gigantism	9.8%
82	Spinal Neoplasms	9.8%
83	Spondylitis	9.8%
84	Osteoarthritis, Knee	9.8%
85	Arthritis, Gouty	9.4%
86	Prognathism	9.4%
87	Bone Diseases, Endocrine	9.4%
88	Noonan Syndrome	9.2%
89	Bone Diseases, Infectious	9.2%
90	Bone neoplasms	9.2%
91	Compartment syndromes	9.2%
92	Maxillary Diseases	9.2%
93	Osteopenia	9.2%
94	Tendinitis	9.2%
95	Tendinopathy	9.2%
96	Bone Resorption	9.1%
97	Hemarthrosis	9.1%
98	Myositis	9.1%
99	Tietze's Syndrome	9.1%
100	Isaacs syndrome	9.1%
101	Aseptic Necrosis of Bone	9.1%
102	Myotonic Disorders	9.1%
103	Mandibulofacial Dysostosis	8.8%
104	Arthritis, Psoriatic	8.8%
105	Abnormalities, Drug-Induced	8.4%
106	Situs Inversus	8.4%
107	Rheumatoid Nodule	8.4%
108	Multiple Epiphyseal Dysplasia	8.1%
109	Osteochondrodysplasias	8.1%
110	Medial Tibial Stress Syndrome	7.9%
111	Bronchomalacia	7.8%
112	Tracheomalacia	7.8%
113	Micrognathism	7.8%
114	Pierre Robin Syndrome	7.8%
115	Mitochondrial Myopathies	7.8%
116	Muscle Cramp	7.8%
117	Eosinophilia-Myalgia Syndrome	7.8%
118	Muscle Rigidity	7.7%
119	Muscle Spasticity	7.7%
120	Cogwheel Rigidity	7.7%
121	Nuchal Rigidity	7.7%
122	Goldenhar Syndrome	7.7%
123	Marfan Syndrome	7.6%
124	Arthritis, Reactive	7.6%
125	Congenital Hypothyroidism	7.4%
126	Beckwith-Wiedemann Syndrome	7.4%
127	Wolf-Hirschhorn Syndrome	7.4%
128	Felty Syndrome	7.3%
129	Familial Periodic Paralysis	7.3%
130	Eye Abnormalities	7.3%
131	Cardiovascular Abnormalities	7.3%
132	Spondylarthropathies	7.3%
133	Porencephaly	7.3%
134	Dwarfism	7.2%
135	Retrognathia	7.2%
136	Skin Abnormalities	7.1%
137	Lymphatic Abnormalities	7.1%
138	Congenital Microtia	7.1%
139	Chronic Fatigue Syndrome	7.1%
140	Cleft Palate	7%
141	Congenital diaphragmatic hernia	7%
142	Aicardi's syndrome	7%
143	Muscular Dystrophy	6.9%
144	Discitis	6.9%
145	Giant Cell Epulis	6.9%
146	Muscle Weakness	6.9%
147	Ainhum	6.9%
148	Dysostoses	6.9%
149	Fibrodysplasia Ossificans Progressiva	6.9%
150	Myoglobinuria	6.9%
151	Myositis Ossificans	6.9%
152	Spinal Stenosis	6.9%
153	Spondylosis	6.9%
154	Tenosynovitis	6.9%
155	Intervertebral Disc Degeneration	6.9%
156	Sacroiliitis	6.9%
157	Musculoskeletal Pain	6.8%
158	Basal Cell Nevus Syndrome	6.8%
159	Arthralgia	6.8%
160	Polyarthralgia	6.8%
161	Myotonic Dystrophy	6.7%
162	Limb Deformities, Congenital	6.6%
163	Smith-Magenis syndrome	6.5%
164	Rheumatoid Vasculitis	6.5%
165	Cri-du-Chat Syndrome	6.4%
166	Down Syndrome	6.4%
167	Trisomy 21	6.4%
168	Urogenital Abnormalities	6.3%
169	Cockayne Syndrome	6.2%
170	Tuberculosis, Spinal	6%
171	Eosinophilic Granuloma	6%
172	Myalgia	6%
173	Sicca Syndrome	5.9%
174	Sjogren's Syndrome	5.9%
175	Arthritis, Infectious	5.8%
176	Foot Deformities	5.8%
177	Ectodermal Dysplasia	5.8%
178	Aplasia Cutis Congenita	5.8%
179	Anterior Compartment Syndrome	5.7%
180	Osteomyelitis	5.7%
181	Osteoporosis	5.7%
182	Periostitis	5.7%
183	Enthesopathy	5.7%
184	Bone Demineralization, Pathologic	5.7%
185	Post-Traumatic Osteoporosis	5.7%
186	Arthritis, Experimental	5.7%
187	Abdominal Compartment Syndrome	5.7%
188	Prader-Willi Syndrome	5.7%
189	Alveolar Bone Loss	5.7%
190	Femur Head Necrosis	5.7%
191	Polymyositis	5.7%
192	Osteolysis	5.7%
193	Genetic Diseases, Inborn	5.6%
194	Osteogenesis Imperfecta	5.5%
195	Palatal Neoplasms	5.4%
196	Myotonia Congenita	5.2%
197	CHARGE Syndrome	5.2%
198	Hip Dislocation	5%
199	Shoulder Dislocation	5%
200	Hip Dysplasia	5%
201	Orbital Myositis	4.9%
202	Dupuytren Contracture	4.9%
203	Anencephaly	4.9%
204	Pyomyositis	4.9%
205	Acromegaly	4.9%
206	Joint Tuberculosis	4.9%
207	Tuberculosis, Osteoarticular	4.9%
208	Bone Tuberculosis	4.9%
209	Muscular Dystrophy, Duchenne	4.9%
210	Chondrodysplasia Punctata	4.9%
211	Enchondromatosis	4.9%
212	Lordosis	4.9%
213	Osteosclerosis	4.9%
214	Spondylolysis	4.9%
215	kyphosis	4.9%
216	Kashin-Beck Disease	4.9%
217	Fetal Diseases	4.7%
218	Abnormalities, Radiation-Induced	4.7%
219	Xeroderma	4.6%
220	Mobius Syndrome	4.6%
221	Hypokalemic periodic paralysis	4.6%
222	Welander Distal Myopathy	4.5%
223	Prune Belly Syndrome	4.4%
224	Twins, Conjoined	4.4%
225	Waardenburg Syndrome	4.4%
226	Lower Extremity Deformities, Congenital	4.3%
227	Dural Arteriovenous Fistula	4.3%
228	Dextrocardia	4.3%
229	Rickets	4.3%
230	Pseudohypoparathyroidism	4.3%
231	Kartagener Syndrome	4.3%
232	Shoulder Pain	4.2%
233	Osteoporosis, Postmenopausal	4%
234	Melorheostosis	3.9%
235	Osteopetrosis	3.9%
236	Spondylolisthesis	3.9%
237	Mitochondrial Encephalomyopathies	3.8%
238	Anophthalmos	3.7%
239	Anus, Imperforate	3.7%
240	Hydranencephaly	3.7%
241	Microphthalmos	3.7%
242	Neural Tube Defects	3.7%
243	Tethered Cord Syndrome	3.7%
244	Iniencephaly	3.7%
245	Craniorachischisis	3.7%
246	Exencephaly	3.7%
247	Septo-Optic Dysplasia	3.7%
248	Cortical Dysplasia	3.7%
249	Malformations of Cortical Development	3.7%
250	Anorectal Malformations	3.7%
251	Bloom Syndrome	3.7%
252	Polycystic Kidney Diseases	3.7%
253	Williams Syndrome	3.7%
254	Cystic Fibrosis	3.6%
255	Scimitar Syndrome	3.5%
256	Mastoiditis	3.5%
257	Petrositis	3.5%
258	Retinal Dysplasia	3.4%
259	Aniridia	3.3%
260	Epidermolysis Bullosa	3.3%
261	Blepharophimosis	3.2%
262	Laryngostenosis	3.2%
263	Mouth Abnormalities	3.2%
264	Esophageal Atresia	3.2%
265	Intestinal Atresia	3.2%
266	Horseshoe Kidney	3.2%
267	Meconium Aspiration Syndrome	3.2%
268	Acrodermatitis	3.2%
269	Lymphangiectasis, Intestinal	3.2%
270	Gianotti-Crosti Syndrome	3.2%
271	Dermatomyositis	3.1%
272	Alstrom Syndrome	3.1%
273	Osteomalacia	3%
274	Smith-Lemli-Opitz Syndrome	3%
275	Ichthyosis, X-Linked	3%
276	Choanal Atresia	2.8%
277	Tracheobronchomegaly	2.8%
278	Laryngocele	2.8%
279	Choledochal Cyst	2.8%
280	Hermaphroditism	2.8%
281	Disorders of Sex Development	2.8%
282	Abdominal Cramps	2.8%
283	Amniotic Band Syndrome	2.8%
284	Asphyxia Neonatorum	2.8%
285	Infant, Premature, Diseases	2.8%
286	Infantile Colic	2.8%
287	Cryptorchidism	2.8%
288	Hypospadias	2.8%
289	Central Nervous System Cysts	2.8%
290	Dandy-Walker Syndrome	2.8%
291	POEMS Syndrome	2.8%
292	Pseudoxanthoma Elasticum	2.7%
293	Fragile X Syndrome	2.7%
294	Primary Ciliary Dyskinesia	2.6%
295	Xeroderma Pigmentosum	2.5%
296	Bladder Exstrophy	2.5%
297	Epispadias	2.5%
298	Multicystic Dysplastic Kidney	2.5%
299	Neoplastic Syndromes, Hereditary	2.4%
300	Anemia, Neonatal	2.3%
301	Pelger-Huet Anomaly	2.3%
302	Persistent Fetal Circulation Syndrome	2.3%
303	Werner Syndrome	2.3%
304	Myasthenic Syndromes, Congenital	2.3%
305	Umbilical hernia	2.3%
306	Nose Neoplasms	2.3%
307	Sjogren-Larsson Syndrome	2.2%
308	Renal Osteodystrophy	2.2%
309	Renal rickets	2.2%
310	MELAS Syndrome	2.2%
311	Zellweger Syndrome	2.2%
312	Radicular Cyst	2.2%
313	Turner Syndrome	2.1%
314	Kallmann Syndrome	2.1%
315	Neonatal Abstinence Syndrome	2.1%
316	Ectopia Cordis	2%
317	Meningomyelocele	2%
318	Spina Bifida	2%
319	Single umbilical artery	2%
320	Polycystic Kidney, Autosomal Dominant	2%
321	Fetal Growth Retardation	2%
322	Fetal Hypoxia	2%
323	Congenital nystagmus	2%
324	Fetal Alcohol Spectrum Disorders	2%
325	Toxoplasmosis, Congenital	2%
326	Syphilis, Congenital	2%
327	Anemia, Sickle Cell	1.8%
328	Thalassemia	1.8%
329	Charcot-Marie-Tooth Disease	1.8%
330	Classical Lissencephalies and Subcortical Band Heterotopias	1.8%
331	Autoimmune Lymphoproliferative Syndrome	1.8%
332	Congenital Hyperinsulinism	1.8%
333	Chorioamnionitis	1.8%
334	Aortic coarctation	1.8%
335	Cor Triatriatum	1.8%
336	Coronary Vessel Anomalies	1.8%
337	Dental Enamel Hypoplasia	1.8%
338	Patent ductus arteriosus	1.8%
339	Ebstein Anomaly	1.8%
340	Heart Septal Defects	1.8%
341	Hypodontia	1.8%
342	Macrostomia	1.8%
343	Meningocele	1.8%
344	Microstomia	1.8%
345	Tetralogy of Fallot	1.8%
346	Transposition of Great Vessels	1.8%
347	Hypoplastic Left Heart Syndrome	1.8%
348	May-Thurner Syndrome	1.8%
349	Encephalocele	1.8%
350	Tuberous Sclerosis	1.7%
351	Angioedemas, Hereditary	1.7%
352	Wolff-Parkinson-White Syndrome	1.7%
353	Kearns-Sayre syndrome	1.7%
354	Albinism	1.7%
355	Refsum Disease	1.6%
356	Klinefelter Syndrome	1.5%
357	Long QT Syndrome	1.5%
358	Tricuspid Atresia	1.5%
359	Arrhythmogenic Right Ventricular Dysplasia	1.5%
360	Gonadal Dysgenesis	1.5%
361	Adrenogenital Syndrome	1.5%
362	Ovotesticular Disorders of Sex Development	1.5%
363	Hyperkeratosis, Epidermolytic	1.5%
364	Familial Hypophosphatemic Rickets	1.5%
365	Wiskott-Aldrich Syndrome	1.5%
366	Familial Mediterranean Fever	1.5%
367	Ophthalmia Neonatorum	1.4%
368	Ataxia Telangiectasia	1.3%
369	Paralysis, Obstetric	1.2%
370	Retinopathy of Prematurity	1.2%
371	Amino Acid Metabolism, Inborn Errors	1.2%
372	Carbohydrate Metabolism, Inborn Errors	1.2%
373	Metal Metabolism, Inborn Errors	1.2%
374	Progeria	1.2%
375	Lysosomal Storage Diseases	1.2%
376	Cytochrome-c Oxidase Deficiency	1.2%
377	Peroxisomal Disorders	1.2%
378	Bronchopulmonary Dysplasia	1.2%
379	Dermal Sinus	1.2%
380	Spina Bifida Cystica	1.2%
381	Spina Bifida Occulta	1.2%
382	Lissencephaly	1.2%
383	Polymicrogyria	1.2%
384	Pachygyria	1.2%
385	Schizencephaly	1.2%
386	Periventricular Nodular Heterotopia	1.2%
387	Hyperandrogenism	1.2%
388	Menkes Kinky Hair Syndrome	1.2%
389	Rett Syndrome	1.2%
390	Neuronal Ceroid-Lipofuscinoses	1.1%
391	Respiratory Distress Syndrome, Newborn	1.1%
392	Mucopolysaccharidosis II	1.1%
393	Cutis Laxa	1.1%
394	Retinitis Pigmentosa	1.1%
395	Pigmentary retinopathy	1.1%
396	Porokeratosis	1.1%
397	Keratoderma, Palmoplantar	1.1%
398	Chronic granulomatous disease	1.1%
399	Aortopulmonary Septal Defect	1%
400	Double Outlet Right Ventricle	1%
401	Endocardial Cushion Defects	1%
402	Myocardial bridging	1%
403	Aorticopulmonary Septal Defect	1%
404	Hepatolenticular Degeneration	1%
405	Amyloid Neuropathies, Familial	1%
406	Sickle Cell Trait	1%
407	Duane Retraction Syndrome	0.9%
408	Porphyrias, Hepatic	0.9%
409	Adrenoleukodystrophy	0.9%
410	Peutz-Jeghers Syndrome	0.9%
411	Thrombasthenia	0.9%
412	Antithrombin III Deficiency	0.9%
413	Protein C Deficiency	0.9%
414	Brain Diseases, Metabolic, Inborn	0.9%
415	Afibrinogenemia	0.9%
416	Dystonia Musculorum Deformans	0.9%
417	Factor VII Deficiency	0.9%
418	Factor X Deficiency	0.9%
419	Factor XII Deficiency	0.9%
420	Hemophilia A	0.9%
421	Leukomalacia, Periventricular	0.9%
422	Activated Protein C Resistance	0.9%
423	Factor II deficiency	0.9%
424	Factor VIII Deficiency	0.9%
425	Factor V deficiency	0.9%
426	Factor XI Deficiency	0.9%
427	Hypoprothrombinemias	0.9%
428	Fanconi Anemia	0.9%
429	Nesidioblastosis	0.9%
430	Lafora Disease	0.9%
431	Unverricht-Lundborg Syndrome	0.9%
432	Anemia, Diamond-Blackfan	0.9%
433	Romano-Ward Syndrome	0.9%
434	Hydrops Fetalis	0.9%
435	Multiple Endocrine Neoplasia	0.8%
436	Dermatitis, Atopic	0.8%
437	Acute Chest Syndrome	0.8%
438	Canavan Disease	0.8%
439	Alexander Disease	0.8%
440	Galactosemias	0.8%
441	Urea Cycle Disorders, Inborn	0.8%
442	Tyrosinemias	0.8%
443	Fabry Disease	0.7%
444	Kernicterus	0.7%
445	Behcet Syndrome	0.7%
446	Optic Atrophy, Hereditary, Leber	0.7%
447	Hyperphosphaturia	0.7%
448	Arteriovenous fistula	0.7%
449	Denys-Drash Syndrome	0.7%
450	Truncus Arteriosus, Persistent	0.7%
451	Alkaptonuria	0.7%
452	Glycogen Storage Disease	0.7%
453	Hypophosphatasia	0.7%
454	Propionic acidemia	0.7%
455	Dihydropyrimidine Dehydrogenase Deficiency	0.7%
456	Cystinosis	0.7%
457	Huntington Disease	0.7%
458	Nephroblastoma	0.6%
459	Glycogen storage disease type II	0.6%
460	Homocystinuria	0.6%
461	Leigh Disease	0.6%
462	Hyaline Membrane Disease	0.6%
463	Hypolipoproteinemias	0.6%
464	Papillon-Lefevre Disease	0.6%
465	Hyperlipidemia, Familial Combined	0.6%
466	Hyperlipoproteinemia Type III	0.6%
467	Adenomatous Polyposis Coli	0.6%
468	Mucopolysaccharidosis III	0.5%
469	Lactose Intolerance	0.5%
470	Variegate Porphyria	0.5%
471	Acute intermittent porphyria	0.5%
472	Porphyria Cutanea Tarda	0.5%
473	Hyperhomocysteinemia	0.5%
474	Renal Aminoacidurias	0.5%
475	Fanconi Syndrome	0.5%
476	Pseudohypoaldosteronism	0.5%
477	Liddle Syndrome	0.5%
478	Hyperlipoproteinemia Type IV	0.5%
479	Hyperlipoproteinemia Type V	0.5%
480	Multiple Endocrine Neoplasia Type 1	0.5%
481	Friedreich Ataxia	0.5%
482	Renal tubular acidosis	0.4%
483	Carbamoyl-Phosphate Synthase I Deficiency Disease	0.4%
484	Glycogen Storage Disease Type I	0.4%
485	Glycogen Storage Disease Type V	0.4%
486	Gaucher Disease	0.4%
487	Glycosuria, Renal	0.4%
488	Hypoalphalipoproteinemias	0.3%
489	Cystinuria	0.3%
490	Niemann-Pick Disease, Type C	0.3%
491	Tay-Sachs Disease	0.2%

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