MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Poland Syndrome

(UMLS:C0032357)

Definition:: A syndrome which is characterized by symbrachydactyly and aplasia of the sternal head of pectoralis major.
UMLS ID:: C0032357
MeSH ID:: D011045

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.099.370.894.819.756|C05.660.585.800.756|C05.660.906.819.756

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.621.585.800.756|C16.131.621.906.819.756

Synonym(s)

Poland Syndrome

POLAND SYNDROME

Poland

Poland Anomaly

Poland anomalad

Poland anomaly

Poland syndrome

Poland's anomalad

Poland's syndactyly

10.

Poland's syndrome

11.

Unilateral defect of pectoralis muscle AND syndactyly of hand

12.

Unilateral defect of pectoralis muscle and syndactyly of hand

13.

anomaly polands

14.

poland anomaly

15.

poland syndrome

16.

poland's anomaly

17.

poland's syndrome

18.

polands syndrome

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Cocaine		15797189	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Acrocephalosyndactylia	58.1%
2	Craniosynostosis	42.8%
3	Brachycephaly	42.8%
4	Klippel-Feil Syndrome	37.4%
5	Pectus excavatum	37.2%
6	Arthrogryposis	36.1%
7	Pectus carinatum	34.8%
8	Craniofacial Abnormalities	32.2%
9	Antley-Bixler Syndrome Phenotype	30.4%
10	Amelia	30%
11	Arachnodactyly	30%
12	Ectromelia	30%
13	Hemimelia	30%
14	Phocomelia	30%
15	Sirenomelia	30%
16	Polydactyly	30%
17	Brachydactyly	30%
18	Lower Extremity Deformities, Congenital	30%
19	Upper Extremity Deformities, Congenital	30%
20	Gastroschisis	28.2%
21	Platybasia	27.3%
22	Rubinstein-Taybi Syndrome	26.8%
23	Craniofacial Dysostosis	25.7%
24	Holoprosencephaly	23.1%
25	Maxillofacial Abnormalities	20.4%
26	Plagiocephaly	18.9%
27	Talipes	17.4%
28	Osteoarthropathy, Secondary Hypertrophic	17.4%
29	Limb Deformities, Congenital	17.1%
30	Microcephaly	16.9%
31	Macrocephaly	16.9%
32	Synostosis	16.6%
33	Laryngomalacia	16.4%
34	Osteochondritis	15.2%
35	Marfan Syndrome	15.1%
36	Jaw Abnormalities	15%
37	Syndactyly	15%
38	Noonan Syndrome	14.9%
39	Mandibulofacial Dysostosis	14.8%
40	Abnormalities, Drug-Induced	14.6%
41	Situs Inversus	14.6%
42	Fasciitis	14.5%
43	Foot Deformities	14.5%
44	Arthropathy	14.5%
45	Multiple Epiphyseal Dysplasia	14.3%
46	Osteochondrodysplasias	14.3%
47	Beckwith-Wiedemann Syndrome	14.2%
48	Wolf-Hirschhorn Syndrome	14.2%
49	Nail-Patella Syndrome	14%
50	Gigantism	14%
51	Aicardi's syndrome	13.8%
52	Contracture	13.4%
53	Fasciitis, Plantar	13.4%
54	Congenital clubfoot	13.2%
55	Vertical Talus	13.2%
56	Eye Abnormalities	12.9%
57	Cardiovascular Abnormalities	12.9%
58	Dwarfism	12.9%
59	Jaw Diseases	12.8%
60	Smith-Magenis syndrome	12.7%
61	Skin Abnormalities	12.7%
62	Lymphatic Abnormalities	12.7%
63	Congenital Microtia	12.7%
64	Cri-du-Chat Syndrome	12.6%
65	Down Syndrome	12.6%
66	Trisomy 21	12.6%
67	Cartilage Diseases	12.6%
68	Foot Diseases	12.6%
69	Myopathy	12.6%
70	Rheumatism	12.6%
71	Chondromalacia	12.6%
72	Congenital diaphragmatic hernia	12.5%
73	Hyperostosis	12.3%
74	Osteitis	12.3%
75	Osteitis Deformans	12.3%
76	Osteochondrosis	12.3%
77	Spinal Diseases	12.3%
78	Goldenhar Syndrome	12%
79	Porencephaly	11.8%
80	Fibromyalgia	11.7%
81	Polymyalgia Rheumatica	11.7%
82	Metatarsalgia	11.7%
83	Ectodermal Dysplasia	11.4%
84	Aplasia Cutis Congenita	11.4%
85	Urogenital Abnormalities	11.4%
86	Prader-Willi Syndrome	11.3%
87	Cockayne Syndrome	11.2%
88	Gout	11%
89	Basal Cell Nevus Syndrome	10.9%
90	Bone Diseases, Endocrine	10.9%
91	Bone Diseases, Infectious	10.7%
92	Bone neoplasms	10.7%
93	Osteopenia	10.7%
94	Prognathism	10.6%
95	Bone Resorption	10.6%
96	Aseptic Necrosis of Bone	10.6%
97	Bronchomalacia	10.5%
98	Tracheomalacia	10.5%
99	Spinal Neoplasms	10.3%
100	Spondylitis	10.3%
101	Micrognathism	10.1%
102	Pierre Robin Syndrome	10.1%
103	Cleft Palate	10%
104	Congenital Hypothyroidism	10%
105	Bone Diseases	10%
106	Poland Syndrome	9.9%
107	CHARGE Syndrome	9.8%
108	Anencephaly	9.7%
109	Genetic Diseases, Inborn	9.4%
110	Kartagener Syndrome	9.3%
111	Retrognathia	9.3%
112	Temporomandibular Joint Disorders	9.2%
113	Rheumatic Fever	9.2%
114	Ischemic contracture	8.9%
115	Osteogenesis Imperfecta	8.9%
116	Abnormalities, Radiation-Induced	8.8%
117	Xeroderma	8.7%
118	Mobius Syndrome	8.7%
119	Dural Arteriovenous Fistula	8.7%
120	Dextrocardia	8.6%
121	Osteoarthritis, Spine	8.6%
122	Rheumatoid Arthritis	8.2%
123	Juvenile arthritis	8.2%
124	Fetal Diseases	8.1%
125	Prune Belly Syndrome	8%
126	Twins, Conjoined	8%
127	Waardenburg Syndrome	8%
128	Arthritis	7.7%
129	Bursitis	7.7%
130	Joint Instability	7.7%
131	Myofascial Pain Syndromes	7.7%
132	Rhabdomyolysis	7.7%
133	Synovitis	7.7%
134	Joint laxity	7.7%
135	Polyarthritis	7.7%
136	Frozen shoulder	7.7%
137	Patellofemoral Pain Syndrome	7.7%
138	Hip Contracture	7.6%
139	Periarthritis	7.6%
140	Temporomandibular Joint Dysfunction Syndrome	7.5%
141	Eosinophilic Granuloma	7.4%
142	Scimitar Syndrome	7.2%
143	Polycystic Kidney Diseases	7.2%
144	Williams Syndrome	7.2%
145	Muscular Dystrophy	7%
146	Anophthalmos	7%
147	Anus, Imperforate	7%
148	Hydranencephaly	7%
149	Microphthalmos	7%
150	Neural Tube Defects	7%
151	Tethered Cord Syndrome	7%
152	Iniencephaly	7%
153	Craniorachischisis	7%
154	Exencephaly	7%
155	Septo-Optic Dysplasia	7%
156	Cortical Dysplasia	7%
157	Malformations of Cortical Development	7%
158	Anorectal Malformations	7%
159	Bloom Syndrome	6.9%
160	Ainhum	6.8%
161	Spinal Stenosis	6.8%
162	Spondylosis	6.8%
163	Intervertebral Disc Degeneration	6.8%
164	Chondrodysplasia Punctata	6.8%
165	Enchondromatosis	6.8%
166	Osteosclerosis	6.8%
167	Kashin-Beck Disease	6.8%
168	Compartment syndromes	6.7%
169	Maxillary Diseases	6.7%
170	Tendinitis	6.7%
171	Tendinopathy	6.7%
172	Cystic Fibrosis	6.7%
173	Alstrom Syndrome	6.7%
174	Arthritis, Gouty	6.7%
175	Retinal Dysplasia	6.7%
176	Hemarthrosis	6.6%
177	Myositis	6.6%
178	Tietze's Syndrome	6.6%
179	Isaacs syndrome	6.6%
180	Myotonic Disorders	6.6%
181	Aniridia	6.6%
182	Epidermolysis Bullosa	6.5%
183	Ankylosing spondylitis	6.4%
184	Myotonic Dystrophy	6.3%
185	Ichthyosis, X-Linked	6.3%
186	Familial Periodic Paralysis	6.2%
187	Discitis	6.2%
188	Osteoarthritis, Knee	6.2%
189	Blepharophimosis	6.2%
190	Laryngostenosis	6.2%
191	Mouth Abnormalities	6.2%
192	Smith-Lemli-Opitz Syndrome	6.1%
193	Esophageal Atresia	6.1%
194	Intestinal Atresia	6.1%
195	Horseshoe Kidney	6.1%
196	Acrodermatitis	6.1%
197	Lymphangiectasis, Intestinal	6.1%
198	Gianotti-Crosti Syndrome	6.1%
199	Meconium Aspiration Syndrome	6%
200	Osteomyelitis	5.9%
201	Osteoporosis	5.9%
202	Periostitis	5.9%
203	Bone Demineralization, Pathologic	5.9%
204	Post-Traumatic Osteoporosis	5.9%
205	Medial Tibial Stress Syndrome	5.9%
206	Alveolar Bone Loss	5.9%
207	Femur Head Necrosis	5.9%
208	Osteolysis	5.9%
209	Mitochondrial Myopathies	5.8%
210	Muscle Cramp	5.8%
211	Eosinophilia-Myalgia Syndrome	5.8%
212	Fragile X Syndrome	5.8%
213	Muscle Rigidity	5.8%
214	Muscle Spasticity	5.8%
215	Cogwheel Rigidity	5.8%
216	Nuchal Rigidity	5.8%
217	Arthritis, Psoriatic	5.7%
218	Choanal Atresia	5.5%
219	Tracheobronchomegaly	5.5%
220	Laryngocele	5.5%
221	Tuberculosis, Spinal	5.5%
222	Choledochal Cyst	5.5%
223	Hermaphroditism	5.5%
224	Disorders of Sex Development	5.5%
225	Pseudoxanthoma Elasticum	5.5%
226	Muscular Dystrophy, Duchenne	5.5%
227	Cryptorchidism	5.5%
228	Hypospadias	5.5%
229	Central Nervous System Cysts	5.4%
230	Rheumatoid Nodule	5.4%
231	Dandy-Walker Syndrome	5.4%
232	Bone Diseases, Developmental	5.4%
233	POEMS Syndrome	5.4%
234	Chronic Fatigue Syndrome	5.3%
235	Primary Ciliary Dyskinesia	5.3%
236	Giant Cell Epulis	5.2%
237	Muscle Weakness	5.2%
238	Turner Syndrome	5.2%
239	Musculoskeletal Pain	5.2%
240	Acromegaly	5.1%
241	Joint Tuberculosis	5.1%
242	Tuberculosis, Osteoarticular	5.1%
243	Bone Tuberculosis	5.1%
244	Arthralgia	5.1%
245	Polyarthralgia	5.1%
246	Pseudohypoparathyroidism	5.1%
247	Xeroderma Pigmentosum	5.1%
248	Bladder Exstrophy	4.9%
249	Epispadias	4.9%
250	Multicystic Dysplastic Kidney	4.9%
251	Abdominal Cramps	4.9%
252	Amniotic Band Syndrome	4.9%
253	Asphyxia Neonatorum	4.9%
254	Infant, Premature, Diseases	4.9%
255	Infantile Colic	4.9%
256	Felty Syndrome	4.8%
257	Sjogren-Larsson Syndrome	4.8%
258	Spondylarthropathies	4.8%
259	Myotonia Congenita	4.8%
260	Arthritis, Reactive	4.6%
261	Myalgia	4.6%
262	Rickets	4.6%
263	Zellweger Syndrome	4.5%
264	Bunion	4.4%
265	Fibrodysplasia Ossificans Progressiva	4.4%
266	Myoglobinuria	4.4%
267	Myositis Ossificans	4.4%
268	Tenosynovitis	4.4%
269	Sacroiliitis	4.4%
270	Kallmann Syndrome	4.4%
271	Melorheostosis	4.4%
272	Osteopetrosis	4.4%
273	Rheumatoid Vasculitis	4.4%
274	Neoplastic Syndromes, Hereditary	4.3%
275	Classical Lissencephalies and Subcortical Band Heterotopias	4.3%
276	Polycystic Kidney, Autosomal Dominant	4.3%
277	Anemia, Neonatal	4.2%
278	Pelger-Huet Anomaly	4.2%
279	Persistent Fetal Circulation Syndrome	4.2%
280	Werner Syndrome	4.2%
281	Myasthenic Syndromes, Congenital	4.2%
282	Umbilical hernia	4.2%
283	Ectopia Cordis	4.1%
284	Meningomyelocele	4.1%
285	Spina Bifida	4.1%
286	Single umbilical artery	4.1%
287	Lordosis	4.1%
288	Spondylolysis	4.1%
289	kyphosis	4.1%
290	Welander Distal Myopathy	4.1%
291	Sicca Syndrome	4%
292	Sjogren's Syndrome	4%
293	Palatal Neoplasms	4%
294	Charcot-Marie-Tooth Disease	3.9%
295	Arthritis, Infectious	3.8%
296	Anterior Compartment Syndrome	3.8%
297	Enthesopathy	3.8%
298	Arthritis, Experimental	3.8%
299	Abdominal Compartment Syndrome	3.8%
300	Tuberous Sclerosis	3.8%
301	Polymyositis	3.8%
302	Neonatal Abstinence Syndrome	3.7%
303	Klinefelter Syndrome	3.7%
304	Fetal Growth Retardation	3.7%
305	Fetal Hypoxia	3.7%
306	Congenital nystagmus	3.7%
307	Fetal Alcohol Spectrum Disorders	3.7%
308	Hypokalemic periodic paralysis	3.7%
309	Toxoplasmosis, Congenital	3.6%
310	Aortic coarctation	3.6%
311	Cor Triatriatum	3.6%
312	Coronary Vessel Anomalies	3.6%
313	Dental Enamel Hypoplasia	3.6%
314	Patent ductus arteriosus	3.6%
315	Ebstein Anomaly	3.6%
316	Heart Septal Defects	3.6%
317	Hypodontia	3.6%
318	Macrostomia	3.6%
319	Meningocele	3.6%
320	Microstomia	3.6%
321	Syphilis, Congenital	3.6%
322	Tetralogy of Fallot	3.6%
323	Transposition of Great Vessels	3.6%
324	Hypoplastic Left Heart Syndrome	3.6%
325	May-Thurner Syndrome	3.6%
326	Encephalocele	3.6%
327	Refsum Disease	3.6%
328	Wolff-Parkinson-White Syndrome	3.6%
329	Anemia, Sickle Cell	3.6%
330	Thalassemia	3.6%
331	Osteoporosis, Postmenopausal	3.5%
332	Albinism	3.5%
333	Hyperkeratosis, Epidermolytic	3.5%
334	Hip Dislocation	3.4%
335	Shoulder Dislocation	3.4%
336	Hip Dysplasia	3.4%
337	Orbital Myositis	3.4%
338	Dupuytren Contracture	3.3%
339	Pyomyositis	3.3%
340	Autoimmune Lymphoproliferative Syndrome	3.3%
341	Congenital Hyperinsulinism	3.3%
342	Chorioamnionitis	3.3%
343	Angioedemas, Hereditary	3.2%
344	Long QT Syndrome	3.2%
345	Tricuspid Atresia	3.2%
346	Arrhythmogenic Right Ventricular Dysplasia	3.2%
347	Gonadal Dysgenesis	3.2%
348	Adrenogenital Syndrome	3.2%
349	Ovotesticular Disorders of Sex Development	3.2%
350	Dysostoses	3.2%
351	Mastoiditis	3.1%
352	Petrositis	3.1%
353	Hyperandrogenism	3%
354	Wiskott-Aldrich Syndrome	2.9%
355	Shoulder Pain	2.9%
356	Spondylolisthesis	2.8%
357	Osteomalacia	2.8%
358	Dermal Sinus	2.7%
359	Spina Bifida Cystica	2.7%
360	Spina Bifida Occulta	2.7%
361	Lissencephaly	2.7%
362	Polymicrogyria	2.7%
363	Pachygyria	2.7%
364	Schizencephaly	2.7%
365	Periventricular Nodular Heterotopia	2.7%
366	Familial Mediterranean Fever	2.7%
367	Mitochondrial Encephalomyopathies	2.7%
368	Ophthalmia Neonatorum	2.6%
369	Menkes Kinky Hair Syndrome	2.6%
370	Ataxia Telangiectasia	2.5%
371	Mucopolysaccharidosis II	2.5%
372	Aortopulmonary Septal Defect	2.4%
373	Double Outlet Right Ventricle	2.4%
374	Endocardial Cushion Defects	2.4%
375	Rett Syndrome	2.4%
376	Myocardial bridging	2.4%
377	Aorticopulmonary Septal Defect	2.4%
378	Paralysis, Obstetric	2.3%
379	Retinopathy of Prematurity	2.3%
380	Amino Acid Metabolism, Inborn Errors	2.3%
381	Carbohydrate Metabolism, Inborn Errors	2.3%
382	Metal Metabolism, Inborn Errors	2.3%
383	Progeria	2.3%
384	Lysosomal Storage Diseases	2.3%
385	Cytochrome-c Oxidase Deficiency	2.3%
386	Peroxisomal Disorders	2.3%
387	Bronchopulmonary Dysplasia	2.3%
388	Neuronal Ceroid-Lipofuscinoses	2.3%
389	Hepatolenticular Degeneration	2.2%
390	Amyloid Neuropathies, Familial	2.1%
391	Nose Neoplasms	2.1%
392	Adrenoleukodystrophy	2.1%
393	Romano-Ward Syndrome	2.1%
394	Sickle Cell Trait	2.1%
395	Renal Osteodystrophy	2.1%
396	Renal rickets	2.1%
397	Respiratory Distress Syndrome, Newborn	2.1%
398	Cutis Laxa	2%
399	Retinitis Pigmentosa	2%
400	Pigmentary retinopathy	2%
401	Porokeratosis	2%
402	Keratoderma, Palmoplantar	2%
403	Chronic granulomatous disease	2%
404	Dermatomyositis	1.9%
405	Hydrops Fetalis	1.9%
406	MELAS Syndrome	1.9%
407	Duane Retraction Syndrome	1.8%
408	Porphyrias, Hepatic	1.8%
409	Peutz-Jeghers Syndrome	1.8%
410	Thrombasthenia	1.8%
411	Antithrombin III Deficiency	1.8%
412	Protein C Deficiency	1.8%
413	Brain Diseases, Metabolic, Inborn	1.8%
414	Afibrinogenemia	1.8%
415	Dystonia Musculorum Deformans	1.8%
416	Factor VII Deficiency	1.8%
417	Factor X Deficiency	1.8%
418	Factor XII Deficiency	1.8%
419	Hemophilia A	1.8%
420	Leukomalacia, Periventricular	1.8%
421	Activated Protein C Resistance	1.8%
422	Factor II deficiency	1.8%
423	Factor VIII Deficiency	1.8%
424	Factor V deficiency	1.8%
425	Factor XI Deficiency	1.8%
426	Hypoprothrombinemias	1.8%
427	Truncus Arteriosus, Persistent	1.8%
428	Fanconi Anemia	1.8%
429	Nesidioblastosis	1.8%
430	Lafora Disease	1.8%
431	Unverricht-Lundborg Syndrome	1.8%
432	Anemia, Diamond-Blackfan	1.8%
433	Acute Chest Syndrome	1.8%
434	Fabry Disease	1.8%
435	Arteriovenous fistula	1.8%
436	Galactosemias	1.7%
437	Urea Cycle Disorders, Inborn	1.7%
438	Tyrosinemias	1.7%
439	Canavan Disease	1.7%
440	Alexander Disease	1.7%
441	Familial Hypophosphatemic Rickets	1.7%
442	Denys-Drash Syndrome	1.7%
443	Multiple Endocrine Neoplasia	1.7%
444	Dermatitis, Atopic	1.6%
445	Optic Atrophy, Hereditary, Leber	1.6%
446	Hyperphosphaturia	1.6%
447	Kernicterus	1.5%
448	Behcet Syndrome	1.5%
449	Glycogen storage disease type II	1.5%
450	Alkaptonuria	1.4%
451	Glycogen Storage Disease	1.4%
452	Hypophosphatasia	1.4%
453	Propionic acidemia	1.4%
454	Dihydropyrimidine Dehydrogenase Deficiency	1.4%
455	Cystinosis	1.4%
456	Huntington Disease	1.4%
457	Homocystinuria	1.3%
458	Leigh Disease	1.3%
459	Mucopolysaccharidosis III	1.3%
460	Nephroblastoma	1.2%
461	Hyaline Membrane Disease	1.2%
462	Hypolipoproteinemias	1.2%
463	Papillon-Lefevre Disease	1.2%
464	Radicular Cyst	1.2%
465	Hyperlipidemia, Familial Combined	1.2%
466	Hyperlipoproteinemia Type III	1.2%
467	Adenomatous Polyposis Coli	1.1%
468	Kearns-Sayre syndrome	1.1%
469	Lactose Intolerance	1.1%
470	Variegate Porphyria	1.1%
471	Acute intermittent porphyria	1.1%
472	Porphyria Cutanea Tarda	1.1%
473	Hyperhomocysteinemia	1.1%
474	Renal Aminoacidurias	1.1%
475	Fanconi Syndrome	1.1%
476	Pseudohypoaldosteronism	1.1%
477	Liddle Syndrome	1.1%
478	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.1%
479	Hyperlipoproteinemia Type IV	1.1%
480	Hyperlipoproteinemia Type V	1.1%
481	Gaucher Disease	1%
482	Multiple Endocrine Neoplasia Type 1	1%
483	Friedreich Ataxia	1%
484	Renal tubular acidosis	1%
485	Glycogen Storage Disease Type I	0.9%
486	Glycogen Storage Disease Type V	0.9%
487	Glycosuria, Renal	0.8%
488	Hypoalphalipoproteinemias	0.8%
489	Niemann-Pick Disease, Type C	0.8%
490	Tay-Sachs Disease	0.8%
491	Cystinuria	0.7%

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