MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Porokeratosis

(UMLS:C0162839)

Definition:: A heritable disorder of faulty keratinization characterized by the proliferation of abnormal clones of KERATINOCYTES and lesions showing varying atrophic patches surrounded by an elevated, keratotic border. These keratotic lesions can progress to overt cutaneous neoplasm. Several clinical variants are recognized, including porokeratosis of Mibelli, linear porokeratosis, disseminated superficial actinic porokeratosis, palmoplantar porokeratosis, and punctate porokeratosis.
UMLS ID:: C0162839
MeSH ID:: D017499

Classification 1:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.320.850.730

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.428.750|C17.800.827.730

Synonym(s)

Porokeratosis

Porokeratosis, NOS

porokeratosis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Temozolomide	FAERS: 7		US FAERS
2	Tacrolimus	FAERS: 6		US FAERS
3	Prednisone	FAERS: 5		US FAERS
4	Alendronate	FAERS: 2		US FAERS
5	Fingolimod Hydrochloride	FAERS: 2		US FAERS
6	Hydroxyurea	FAERS: 2		US FAERS
7	Paclitaxel	FAERS: 2		US FAERS
8	3-ingenyl angelate	FAERS: 1		US FAERS
9	Celecoxib	FAERS: 1		US FAERS
10	Cyclosporine	FAERS: 1		US FAERS
11	Dabigatran	FAERS: 1		US FAERS
12	Glatiramer Acetate	FAERS: 1		US FAERS
13	Testosterone	FAERS: 1		US FAERS
14	Valsartan	FAERS: 1		US FAERS
15	aliskiren	FAERS: 1		OFFSIDES US FAERS
16	palbociclib	FAERS: 1		US FAERS
17	Alitretinoin		16144296	CTD
18	Daunorubicin			OFFSIDES
19	Etoposide			OFFSIDES
20	Floxacillin			OFFSIDES
21	Ibandronic Acid			OFFSIDES
22	Pyridostigmine Bromide			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Keratoderma, Palmoplantar	60%
2	Epidermolysis Bullosa	50%
3	Dermatitis, Atopic	48.3%
4	Cutis Laxa	44.9%
5	Papillon-Lefevre Disease	44.3%
6	Xeroderma Pigmentosum	43.9%
7	Ectodermal Dysplasia	41.7%
8	Aplasia Cutis Congenita	41.7%
9	Pyoderma Gangrenosum	40%
10	Ichthyosis, X-Linked	39.5%
11	Pseudoxanthoma Elasticum	36.1%
12	Xeroderma	35.6%
13	Sjogren-Larsson Syndrome	35.6%
14	Albinism	35.5%
15	Hyperkeratosis, Epidermolytic	34.8%
16	Cholesteatoma	33.3%
17	Parakeratosis	33.3%
18	Lupus Erythematosus, Cutaneous	32.9%
19	Panniculitis	32.9%
20	Systemic Scleroderma	32.9%
21	Morphea	32.9%
22	Porphyrias, Hepatic	32.7%
23	Acne Vulgaris	32%
24	Contact Dermatitis	32%
25	Eczema	32%
26	Erythema Multiforme	32%
27	Intertrigo	32%
28	Neurodermatitis	32%
29	Rhinophyma	32%
30	Perioral Dermatitis	32%
31	Acne	32%
32	Breast Diseases	30.5%
33	Dermatitis	30.5%
34	Exanthema	30.5%
35	Facial Dermatoses	30.5%
36	Hair Diseases	30.5%
37	Hand Dermatoses	30.5%
38	keratoacanthoma	30.5%
39	Nail Diseases	30.5%
40	Photosensitivity Disorders	30.5%
41	Prurigo	30.5%
42	Pyoderma	30.5%
43	Rosacea	30.5%
44	Sebaceous Gland Diseases	30.5%
45	Skin Diseases, Vesiculobullous	30.5%
46	Skin Ulcer	30.5%
47	Sweat Gland Diseases	30.5%
48	Skin Diseases, Papulosquamous	30.5%
49	Skin Diseases, Vascular	30.5%
50	Acneiform Eruptions	30.5%
51	Ocular Rosacea	30.5%
52	Subcorneal pustular dermatosis	30.5%
53	Erythematotelangiectatic Rosacea	30.5%
54	Papulopustular Rosacea	30.5%
55	Chronic Actinic Dermatitis	30.5%
56	Dermatitis, Phototoxic	29.5%
57	Pityriasis Lichenoides et Varioliformis Acuta	29.5%
58	Pityriasis Lichenoides	29.5%
59	Phototoxicity	29.5%
60	Acrodermatitis	28.9%
61	Gianotti-Crosti Syndrome	28.9%
62	Skin Abnormalities	28.8%
63	Foot Ulcer	27.8%
64	Actinic keratosis	27%
65	Dermatitis Herpetiformis	27%
66	Sebaceous Gland Neoplasms	26.7%
67	Panniculitis, Lupus Erythematosus	26.4%
68	Necrobiosis Lipoidica Diabeticorum	25.6%
69	Foot Diseases	25.4%
70	Dermatitis, Photoallergic	25.2%
71	Skin Diseases, Infectious	24.7%
72	Skin Neoplasms	24.7%
73	Pigmentation Disorders	24.7%
74	Behcet Syndrome	24.4%
75	Lipomatosis	24.3%
76	Pruritus	24.3%
77	Erythema	24.3%
78	Necrolytic Migratory Erythema	24.3%
79	Cutaneous Fistula	24.3%
80	Nephrogenic Fibrosing Dermopathy	24.3%
81	Nephrogenic Systemic Fibrosis	24.3%
82	Variegate Porphyria	23.9%
83	Acute intermittent porphyria	23.9%
84	Porphyria Cutanea Tarda	23.9%
85	Dermatitis, Irritant	23.7%
86	Acne Conglobata	23.7%
87	Erythema Induratum	23.2%
88	Dermatomyositis	23%
89	Urticaria Pigmentosa	23%
90	Nail-Patella Syndrome	22.3%
91	Lupus Erythematosus, Discoid	21.3%
92	Scleroderma, Limited	21.3%
93	Dermatitis, Occupational	20.5%
94	Mastocytosis	20.1%
95	Erythema Infectiosum	20.1%
96	Anhidrosis	20%
97	Pressure Ulcer	20%
98	Exanthema Subitum	20%
99	Folliculitis	20%
100	Foot Dermatoses	20%
101	Gynecomastia	20%
102	Hypertrichosis	20%
103	Hypohidrosis	20%
104	Hypotrichosis	20%
105	Leg Ulcer	20%
106	Miliaria	20%
107	Parapsoriasis	20%
108	Pityriasis	20%
109	Psoriasis	20%
110	Sweet Syndrome	20%
111	Hidradenitis	20%
112	Onycholysis	20%
113	Miliaria Rubra	20%
114	Hyperpigmentation	20%
115	Lichenoid Eruptions	20%
116	Chloracne	20%
117	Dermatitis, Allergic Contact	19.8%
118	Erythema Nodosum	19.7%
119	Toxic Epidermal Necrolysis	19.6%
120	Stevens-Johnson Syndrome	19.6%
121	Diaper Rash	19.6%
122	Tinea Capitis	18.2%
123	Onychomycosis	18.2%
124	Connective Tissue Diseases	17.5%
125	Ecthyma	17.3%
126	Granuloma Annulare	16.6%
127	Acantholysis	16.2%
128	Breast Cyst	16.2%
129	Pemphigoid, Benign Mucous Membrane	16.2%
130	Pemphigus	16.2%
131	Piedra	16.2%
132	Sunburn	16.2%
133	Argyria	16%
134	Hirsutism	16%
135	Lactation Disorder	16%
136	Mastitis	16%
137	Urticaria	16%
138	Adiposis Dolorosa	15.9%
139	Pruritus Vulvae	15.9%
140	Mastocytoma	15.8%
141	Pruritus Ani	15.8%
142	Angioedemas, Hereditary	15.6%
143	Keratosis	15.3%
144	Menkes Kinky Hair Syndrome	15%
145	Lichen Planus	14.9%
146	Melanosis	14.9%
147	Chloasma	14.9%
148	Pityriasis Rosea	14.9%
149	Pityriasis Rubra Pilaris	14.9%
150	Vitiligo	14.9%
151	Lichen Nitidus	14.9%
152	Hidradenitis Suppurativa	14.8%
153	Osteogenesis Imperfecta	14.5%
154	Erythema Chronicum Migrans	13.7%
155	Dermatomycoses	13.5%
156	Mucocutaneous Lymph Node Syndrome	13.5%
157	Skin Diseases, Bacterial	13.5%
158	Tinea Pedis	13.4%
159	Drug Eruptions	13.3%
160	Lipodystrophy	13.3%
161	Livedo Reticularis	13.3%
162	Porokeratosis	13.3%
163	Malignant Atrophic Papulosis	13.3%
164	Polyarteritis Nodosa	13.2%
165	Takayasu Arteritis	13.2%
166	Neoplastic Syndromes, Hereditary	12.7%
167	Marfan Syndrome	12.5%
168	Aicardi's syndrome	12.4%
169	CHARGE Syndrome	12.4%
170	Acanthosis Nigricans	12.3%
171	Alopecia Areata	12.3%
172	Lentigo	12.3%
173	Fragile X Syndrome	12.2%
174	Multiple Epiphyseal Dysplasia	12.2%
175	Osteochondrodysplasias	12.2%
176	Pelger-Huet Anomaly	12.2%
177	Werner Syndrome	12.2%
178	Myasthenic Syndromes, Congenital	12.2%
179	Peutz-Jeghers Syndrome	12.1%
180	Alopecia	12.1%
181	Sweating, Gustatory	12.1%
182	Androgenetic Alopecia	12.1%
183	Auriculotemporal Syndrome	12.1%
184	Lice Infestations	11.9%
185	Varicose Ulcer	11.9%
186	Breast Neoplasms, Male	11.9%
187	Triple Negative Breast Neoplasms	11.9%
188	Cystic Fibrosis	11.9%
189	Galactorrhea	11.8%
190	Mycetoma	11.8%
191	Mucopolysaccharidosis II	11.5%
192	Anemia, Sickle Cell	11.3%
193	Thalassemia	11.3%
194	Muscular Dystrophy, Duchenne	11.3%
195	Beckwith-Wiedemann Syndrome	11.1%
196	Wolf-Hirschhorn Syndrome	11.1%
197	Dwarfism	10.5%
198	Cockayne Syndrome	10.3%
199	Collagen Diseases	10.2%
200	Mixed Connective Tissue Disease	10.2%
201	Mucinoses	10.2%
202	Larva Migrans	10.1%
203	Leishmaniasis	10.1%
204	Molluscum Contagiosum	10.1%
205	Muscular Dystrophy	10.1%
206	Lichen Planus, Oral	10%
207	Angioedema	10%
208	Familial Mediterranean Fever	10%
209	Onchocerciasis	10%
210	Chromoblastomycosis	9.9%
211	Dermatophytosis	9.9%
212	Sporotrichosis	9.9%
213	Tinea	9.9%
214	Tinea Versicolor	9.9%
215	Trichophytosis	9.9%
216	Hyalohyphomycosis	9.9%
217	Acute Generalized Exanthematous Pustulosis	9.8%
218	Alstrom Syndrome	9.8%
219	Rett Syndrome	9.8%
220	Smith-Magenis syndrome	9.6%
221	Cri-du-Chat Syndrome	9.5%
222	Down Syndrome	9.5%
223	Trisomy 21	9.5%
224	Homocystinuria	9.3%
225	Wiskott-Aldrich Syndrome	8.8%
226	Deformity	8.8%
227	Autoimmune Lymphoproliferative Syndrome	8.7%
228	CREST Syndrome	8.7%
229	Warts	8.7%
230	Kartagener Syndrome	8.7%
231	Holoprosencephaly	8.6%
232	Mucopolysaccharidosis III	8.5%
233	Candidiasis, Chronic Mucocutaneous	8.5%
234	Cutaneous Candidiasis	8.5%
235	Cartilage Diseases	8.5%
236	Erysipelas	8.5%
237	Rheumatism	8.5%
238	Serum Sickness	8.5%
239	Staphylococcal Skin Infections	8.5%
240	Chondromalacia	8.5%
241	Erythrasma	8.4%
242	Carcinoma, Lobular	8.4%
243	Arthritis, Psoriatic	8.4%
244	Sickle Cell Trait	8.4%
245	Prader-Willi Syndrome	8.3%
246	Leishmaniasis, Cutaneous	8.2%
247	Lupus Erythematosus, Systemic	8.2%
248	Overlap syndrome	8.2%
249	Eczema Herpeticum	8.2%
250	Fusariosis	8.2%
251	Amino Acid Metabolism, Inborn Errors	8%
252	Carbohydrate Metabolism, Inborn Errors	8%
253	Metal Metabolism, Inborn Errors	8%
254	Progeria	8%
255	Lysosomal Storage Diseases	8%
256	Smith-Lemli-Opitz Syndrome	8%
257	Cytochrome-c Oxidase Deficiency	8%
258	Peroxisomal Disorders	8%
259	Neuronal Ceroid-Lipofuscinoses	8%
260	Myotonic Dystrophy	7.9%
261	Giant Cell Arteritis	7.9%
262	Temporal Arteritis	7.9%
263	Rubinstein-Taybi Syndrome	7.6%
264	Primary Ciliary Dyskinesia	7.5%
265	Polycystic Kidney Diseases	7.5%
266	Williams Syndrome	7.5%
267	Kallmann Syndrome	7.5%
268	Tuberous Sclerosis	7.5%
269	Adrenoleukodystrophy	7.4%
270	Hereditary Angioedema Type III	7.3%
271	Hereditary Angioedema Types I and II	7.3%
272	Epidermodysplasia Verruciformis	7.1%
273	Herpes Labialis	7.1%
274	Hepatolenticular Degeneration	7.1%
275	Fetal Diseases	7%
276	Diabetic Foot	7%
277	Refsum Disease	7%
278	Staphylococcal Scalded Skin Syndrome	7%
279	Fabry Disease	6.9%
280	Amyloid Neuropathies, Familial	6.9%
281	Retinal Dysplasia	6.8%
282	Aniridia	6.8%
283	Retinitis Pigmentosa	6.7%
284	Pigmentary retinopathy	6.7%
285	Dupuytren Contracture	6.7%
286	Noonan Syndrome	6.7%
287	Scleromyxedema	6.7%
288	Acute Chest Syndrome	6.6%
289	Chronic granulomatous disease	6.6%
290	Blastomycosis	6.6%
291	Welander Distal Myopathy	6.6%
292	Glycogen storage disease type II	6.6%
293	HIV-Associated Lipodystrophy Syndrome	6.5%
294	Galactosemias	6.5%
295	Urea Cycle Disorders, Inborn	6.5%
296	Tyrosinemias	6.5%
297	carbuncle	6.2%
298	Condylomata Acuminata	6.2%
299	Furunculosis	6.2%
300	furuncle	6.2%
301	Impetigo	6.1%
302	Ataxia Telangiectasia	6.1%
303	Rhinoscleroma	6.1%
304	Alkaptonuria	5.9%
305	Glycogen Storage Disease	5.9%
306	Hypophosphatasia	5.9%
307	Propionic acidemia	5.9%
308	Dihydropyrimidine Dehydrogenase Deficiency	5.9%
309	Cystinosis	5.9%
310	Optic Atrophy, Hereditary, Leber	5.9%
311	Hyperphosphaturia	5.9%
312	Duane Retraction Syndrome	5.8%
313	Canavan Disease	5.8%
314	Alexander Disease	5.8%
315	Cellulitis	5.7%
316	Myotonia Congenita	5.7%
317	Thrombasthenia	5.7%
318	Antithrombin III Deficiency	5.7%
319	Protein C Deficiency	5.7%
320	Brain Diseases, Metabolic, Inborn	5.7%
321	Afibrinogenemia	5.7%
322	Dystonia Musculorum Deformans	5.7%
323	Factor VII Deficiency	5.7%
324	Factor X Deficiency	5.7%
325	Factor XII Deficiency	5.7%
326	Hemophilia A	5.7%
327	Activated Protein C Resistance	5.7%
328	Factor II deficiency	5.7%
329	Factor VIII Deficiency	5.7%
330	Factor V deficiency	5.7%
331	Factor XI Deficiency	5.7%
332	Hypoprothrombinemias	5.7%
333	Fanconi Anemia	5.6%
334	Lafora Disease	5.6%
335	Unverricht-Lundborg Syndrome	5.6%
336	Anemia, Diamond-Blackfan	5.6%
337	Polycystic Kidney, Autosomal Dominant	5.6%
338	Classical Lissencephalies and Subcortical Band Heterotopias	5.6%
339	Zellweger Syndrome	5.6%
340	Mesenteric Panniculitis	5.4%
341	Panniculitis, Peritoneal	5.4%
342	Tietze's Syndrome	5.4%
343	Orbital Cellulitis	5.4%
344	Myxoid cyst	5.4%
345	Gaucher Disease	5.4%
346	Leigh Disease	5.4%
347	Myxedema	5.3%
348	Meconium Aspiration Syndrome	5.1%
349	Multiple Endocrine Neoplasia	5.1%
350	Laryngomalacia	5.1%
351	Abdominal Cramps	5.1%
352	Abnormalities, Drug-Induced	5.1%
353	Amniotic Band Syndrome	5.1%
354	Asphyxia Neonatorum	5.1%
355	Infant, Premature, Diseases	5.1%
356	Situs Inversus	5.1%
357	Infantile Colic	5.1%
358	Pectus carinatum	5.1%
359	Congenital Hypothyroidism	5%
360	Tay-Sachs Disease	4.9%
361	Hypolipoproteinemias	4.9%
362	Charcot-Marie-Tooth Disease	4.9%
363	Antley-Bixler Syndrome Phenotype	4.9%
364	Hyperlipidemia, Familial Combined	4.9%
365	Glycogen Storage Disease Type I	4.9%
366	Glycogen Storage Disease Type V	4.9%
367	Hyperlipoproteinemia Type III	4.9%
368	Carbamoyl-Phosphate Synthase I Deficiency Disease	4.9%
369	Mobius Syndrome	4.8%
370	Niemann-Pick Disease, Type C	4.7%
371	Osteochondritis	4.5%
372	Polymyalgia Rheumatica	4.5%
373	Keloid	4.4%
374	Basal Cell Nevus Syndrome	4.4%
375	Familial Periodic Paralysis	4.3%
376	Bronchomalacia	4.2%
377	Tracheomalacia	4.2%
378	Eye Abnormalities	4.2%
379	Lactose Intolerance	4.2%
380	Cardiovascular Abnormalities	4.2%
381	Hyperhomocysteinemia	4.2%
382	Renal Aminoacidurias	4.2%
383	Fanconi Syndrome	4.2%
384	Pseudohypoaldosteronism	4.2%
385	Liddle Syndrome	4.2%
386	Hyperlipoproteinemia Type IV	4.2%
387	Hyperlipoproteinemia Type V	4.2%
388	Lymphatic Abnormalities	4.1%
389	Congenital Microtia	4.1%
390	Hypoalphalipoproteinemias	4.1%
391	Klinefelter Syndrome	4.1%
392	Anemia, Neonatal	4.1%
393	Persistent Fetal Circulation Syndrome	4.1%
394	Congenital diaphragmatic hernia	4%
395	Umbilical hernia	4%
396	Huntington Disease	4%
397	Rheumatoid Arthritis	3.9%
398	Juvenile arthritis	3.9%
399	Anencephaly	3.9%
400	Hydrops Fetalis	3.8%
401	Lupus Nephritis	3.8%
402	Gout	3.7%
403	Multiple Endocrine Neoplasia Type 1	3.7%
404	Pseudohypoparathyroidism	3.7%
405	Friedreich Ataxia	3.7%
406	Renal tubular acidosis	3.7%
407	Turner Syndrome	3.6%
408	Nephroblastoma	3.6%
409	Urogenital Abnormalities	3.5%
410	Hypokalemic periodic paralysis	3.5%
411	Cystinuria	3.5%
412	Neonatal Abstinence Syndrome	3.4%
413	Fetal Growth Retardation	3.4%
414	Fetal Hypoxia	3.4%
415	Congenital nystagmus	3.4%
416	Fetal Alcohol Spectrum Disorders	3.4%
417	Maxillofacial Abnormalities	3.3%
418	Dural Arteriovenous Fistula	3.3%
419	Prune Belly Syndrome	3.3%
420	Twins, Conjoined	3.3%
421	Waardenburg Syndrome	3.3%
422	Toxoplasmosis, Congenital	3.3%
423	Dextrocardia	3.3%
424	Syphilis, Congenital	3.3%
425	Rheumatoid Nodule	3.3%
426	Adenomatous Polyposis Coli	3.3%
427	Familial Hypophosphatemic Rickets	3.2%
428	Arthritis, Gouty	3.1%
429	Glycosuria, Renal	2.9%
430	Congenital Hyperinsulinism	2.9%
431	Chorioamnionitis	2.9%
432	Felty Syndrome	2.8%
433	Anophthalmos	2.7%
434	Anus, Imperforate	2.7%
435	Hydranencephaly	2.7%
436	Microphthalmos	2.7%
437	Neural Tube Defects	2.7%
438	Paralysis, Obstetric	2.7%
439	Retinopathy of Prematurity	2.7%
440	Tethered Cord Syndrome	2.7%
441	Iniencephaly	2.7%
442	Craniorachischisis	2.7%
443	Limb Deformities, Congenital	2.7%
444	Exencephaly	2.7%
445	Septo-Optic Dysplasia	2.7%
446	Craniofacial Abnormalities	2.7%
447	Cortical Dysplasia	2.7%
448	Malformations of Cortical Development	2.7%
449	Anorectal Malformations	2.7%
450	Bloom Syndrome	2.7%
451	Bronchopulmonary Dysplasia	2.6%
452	Scimitar Syndrome	2.6%
453	Microcephaly	2.6%
454	Macrocephaly	2.6%
455	Abnormalities, Radiation-Induced	2.5%
456	Acrocephalosyndactylia	2.5%
457	Denys-Drash Syndrome	2.5%
458	Rheumatoid Vasculitis	2.5%
459	Craniosynostosis	2.5%
460	Syndactyly	2.5%
461	Brachycephaly	2.5%
462	MELAS Syndrome	2.4%
463	Porencephaly	2.3%
464	Blepharophimosis	2.3%
465	Laryngostenosis	2.3%
466	Mouth Abnormalities	2.3%
467	Respiratory Distress Syndrome, Newborn	2.3%
468	Esophageal Atresia	2.2%
469	Intestinal Atresia	2.2%
470	Horseshoe Kidney	2.2%
471	Pectus excavatum	2.2%
472	Klippel-Feil Syndrome	2.2%
473	Gastroschisis	2.2%
474	Synostosis	2.2%
475	Lymphangiectasis, Intestinal	2.2%
476	Sicca Syndrome	2.2%
477	Sjogren's Syndrome	2.2%
478	Ophthalmia Neonatorum	2.2%
479	Cleft Palate	2.1%
480	Jaw Abnormalities	2%
481	Poland Syndrome	2%
482	Amelia	2%
483	Arachnodactyly	2%
484	Ectopia Cordis	2%
485	Ectromelia	2%
486	Hemimelia	2%
487	Meningomyelocele	2%
488	Phocomelia	2%
489	Sirenomelia	2%
490	Spina Bifida	2%
491	Polydactyly	2%
492	Brachydactyly	2%
493	Plagiocephaly	2%
494	Lower Extremity Deformities, Congenital	2%
495	Upper Extremity Deformities, Congenital	2%
496	Single umbilical artery	2%
497	Arthrogryposis	2%
498	Choanal Atresia	2%
499	Tracheobronchomegaly	2%
500	Laryngocele	2%
501	Choledochal Cyst	1.9%
502	Hermaphroditism	1.9%
503	Disorders of Sex Development	1.9%
504	Cryptorchidism	1.9%
505	Hypospadias	1.9%
506	Central Nervous System Cysts	1.9%
507	Dandy-Walker Syndrome	1.9%
508	Leukomalacia, Periventricular	1.9%
509	POEMS Syndrome	1.9%
510	Nesidioblastosis	1.9%
511	Lupus Vasculitis, Central Nervous System	1.9%
512	Micrognathism	1.7%
513	Pierre Robin Syndrome	1.7%
514	Bladder Exstrophy	1.7%
515	Epispadias	1.7%
516	Multicystic Dysplastic Kidney	1.7%
517	Aortic coarctation	1.7%
518	Cor Triatriatum	1.7%
519	Coronary Vessel Anomalies	1.7%
520	Dental Enamel Hypoplasia	1.7%
521	Patent ductus arteriosus	1.7%
522	Ebstein Anomaly	1.7%
523	Heart Septal Defects	1.7%
524	Hyaline Membrane Disease	1.7%
525	Hypodontia	1.7%
526	Macrostomia	1.7%
527	Meningocele	1.7%
528	Microstomia	1.7%
529	Tetralogy of Fallot	1.7%
530	Transposition of Great Vessels	1.7%
531	Hypoplastic Left Heart Syndrome	1.7%
532	May-Thurner Syndrome	1.7%
533	Encephalocele	1.7%
534	Craniofacial Dysostosis	1.6%
535	Dermal Sinus	1.6%
536	Spina Bifida Cystica	1.6%
537	Wolff-Parkinson-White Syndrome	1.6%
538	Spina Bifida Occulta	1.6%
539	Lissencephaly	1.6%
540	Polymicrogyria	1.6%
541	Pachygyria	1.6%
542	Schizencephaly	1.6%
543	Periventricular Nodular Heterotopia	1.6%
544	Retrognathia	1.6%
545	Kernicterus	1.5%
546	Hyperandrogenism	1.5%
547	Long QT Syndrome	1.4%
548	Platybasia	1.4%
549	Tricuspid Atresia	1.4%
550	Arrhythmogenic Right Ventricular Dysplasia	1.4%
551	Gonadal Dysgenesis	1.4%
552	Adrenogenital Syndrome	1.4%
553	Ovotesticular Disorders of Sex Development	1.4%
554	Prognathism	1.4%
555	Aortopulmonary Septal Defect	1.4%
556	Double Outlet Right Ventricle	1.4%
557	Endocardial Cushion Defects	1.4%
558	Myocardial bridging	1.4%
559	Aorticopulmonary Septal Defect	1.4%
560	Truncus Arteriosus, Persistent	1.2%
561	Goldenhar Syndrome	1.2%
562	Mandibulofacial Dysostosis	1.2%
563	Romano-Ward Syndrome	1.2%
564	Talipes	1.1%
565	Congenital clubfoot	1%
566	Vertical Talus	1%
567	Arteriovenous fistula	0.9%

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