MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Polycystic Kidney Diseases

(UMLS:C0022680)

Definition:: Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.
UMLS ID:: C0022680
MeSH ID:: D007690

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.419.403.875

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.419.403.875

Classification 3:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.077.717|C16.320.184.625

Synonym(s)

Polycystic Kidney Diseases

Fibrocystic Renal Disease

PCK - Polycystic kidney disease

PKD - Polycystic Kidney Disease

PKD - Polycystic kidney disease

POLYCYSTIC KIDNEY

POLYCYSTIC KIDNEY DISEASE

POLYCYSTIC RENAL DISEASE

Polycystic Kidney

10.

Polycystic Kidney Disease

11.

Polycystic kidney

12.

Polycystic kidney disease

13.

Polycystic kidney dysplasia

14.

Polycystic kidney, unspecified

15.

Polycystic kidney, unspecified type

16.

congenital polycystic kidney

17.

cyst; kidney, multiple

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Methylprednisolone Acetate	3945365 8724899	CTD
2	Rosiglitazone	20507283	CTD
3	Saponins	12631339	CTD
4	Sirolimus	19321761	CTD
5	Triiodothyronine	8724899	CTD
6	hydrocortisone acetate	1882347 2313979	CTD
7	tubacin	28887310	CTD
8	tubastatin A	28887310	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Multicystic Dysplastic Kidney	32.8%
2	Beckwith-Wiedemann Syndrome	30.1%
3	Wolf-Hirschhorn Syndrome	30.1%
4	Smith-Magenis syndrome	26.6%
5	CHARGE Syndrome	26.6%
6	Holoprosencephaly	26.3%
7	Cri-du-Chat Syndrome	26.3%
8	Down Syndrome	26.3%
9	Trisomy 21	26.3%
10	Anuria	25.8%
11	Nephrolithiasis	25.8%
12	Primary Ciliary Dyskinesia	24.2%
13	Hydronephrosis	23.7%
14	Hyperoxaluria	23.7%
15	Kidney Cortex Necrosis	23.7%
16	Kidney Papillary Necrosis	23.7%
17	Nephritis	23.7%
18	Nephrosclerosis	23.7%
19	Nephrosis	23.7%
20	Perinephritis	23.7%
21	Kidney Failure	23.7%
22	Uremia	23.7%
23	Oxalosis	23.7%
24	Renal Insufficiency	23.7%
25	Ectodermal Dysplasia	23.5%
26	Aplasia Cutis Congenita	23.5%
27	Nail-Patella Syndrome	23.5%
28	Prader-Willi Syndrome	23.3%
29	Zellweger Syndrome	23.2%
30	Alstrom Syndrome	23.1%
31	Urogenital Abnormalities	23%
32	Aicardi's syndrome	22.7%
33	Rubinstein-Taybi Syndrome	22.7%
34	Kartagener Syndrome	22%
35	Cockayne Syndrome	21.1%
36	Prune Belly Syndrome	21%
37	Waardenburg Syndrome	21%
38	Marfan Syndrome	20.6%
39	Diabetes Insipidus	20.6%
40	Hepatorenal Syndrome	20.6%
41	Tuberculosis, Renal	20.5%
42	Diabetic Nephropathy	20.4%
43	Renal hypertension	20.4%
44	Renal Artery Obstruction	20.4%
45	Renal Artery Stenosis	20.4%
46	Nephrocalcinosis	20.3%
47	Kidney Neoplasm	18.5%
48	Mobius Syndrome	18.3%
49	Smith-Lemli-Opitz Syndrome	18.2%
50	Urinary Bladder Diseases	18%
51	Ureteral Diseases	18%
52	Urethral Diseases	18%
53	Urination Disorders	18%
54	Urolithiasis	18%
55	Bladder Exstrophy	17.7%
56	Epispadias	17.7%
57	Bloom Syndrome	17.5%
58	Pyelonephritis	17.5%
59	Fragile X Syndrome	17.3%
60	Renal Aminoacidurias	16.6%
61	Fanconi Syndrome	16.6%
62	Pseudohypoaldosteronism	16.6%
63	Liddle Syndrome	16.6%
64	Kidney Calculi	16.1%
65	Ichthyosis, X-Linked	16.1%
66	Ureterolithiasis	16%
67	Abnormalities, Drug-Induced	15.9%
68	Situs Inversus	15.9%
69	Glycosuria, Renal	15.9%
70	AIDS-Associated Nephropathy	15.8%
71	Glomerulonephritis	15.7%
72	Nephritis, Interstitial	15.7%
73	Lipoid nephrosis	15.7%
74	Nephrotic Syndrome	15.7%
75	Pyelitis	15.7%
76	Pyonephrosis	15.7%
77	Nephrogenic Diabetes Insipidus	15.7%
78	Congenital Nephrogenic Diabetes Insipidus	15.7%
79	Acute kidney injury	15.7%
80	Hyperphosphaturia	15.6%
81	Urinary tract infection	15.6%
82	Cystic Fibrosis	15.4%
83	Renal tubular acidosis	14.7%
84	Fetal Diseases	14%
85	Pyelocystitis	14%
86	Eye Abnormalities	13.8%
87	Neoplastic Syndromes, Hereditary	13.8%
88	Cardiovascular Abnormalities	13.8%
89	Nephroblastoma	13.6%
90	Azotemia	13.6%
91	Horseshoe Kidney	13.5%
92	Skin Abnormalities	13.4%
93	Lymphatic Abnormalities	13.4%
94	Congenital Microtia	13.4%
95	Hypertension, Renovascular	13.4%
96	Multiple Epiphyseal Dysplasia	13.3%
97	Osteochondrodysplasias	13.3%
98	Pelger-Huet Anomaly	13.3%
99	Werner Syndrome	13.3%
100	Myasthenic Syndromes, Congenital	13.3%
101	Congenital diaphragmatic hernia	13.2%
102	Bladder neck obstruction	13.2%
103	Albinism	13.2%
104	Anemia, Sickle Cell	13.1%
105	Anencephaly	13.1%
106	Thalassemia	13.1%
107	Hypospadias	13.1%
108	POEMS Syndrome	13.1%
109	Muscular Dystrophy, Duchenne	13.1%
110	Williams Syndrome	13.1%
111	Renal Osteodystrophy	12.8%
112	Renal rickets	12.8%
113	Kallmann Syndrome	12.8%
114	Cystinuria	12.8%
115	Basal Cell Nevus Syndrome	12.1%
116	Retinal Dysplasia	12%
117	Hermaphroditism	11.9%
118	Disorders of Sex Development	11.9%
119	Aniridia	11.9%
120	Mucopolysaccharidosis II	11.8%
121	Turner Syndrome	11.8%
122	Epidermolysis Bullosa	11.7%
123	Dwarfism	11.7%
124	Hemolytic-Uremic Syndrome	11.7%
125	Balkan Nephropathy	11.7%
126	Focal glomerulosclerosis	11.7%
127	Kidney Failure, Chronic	11.7%
128	Xeroderma	11.6%
129	Maxillofacial Abnormalities	11.6%
130	Dural Arteriovenous Fistula	11.6%
131	Sjogren-Larsson Syndrome	11.5%
132	Dextrocardia	11.5%
133	Ureteral Calculi	11.4%
134	Muscular Dystrophy	11.3%
135	Osteogenesis Imperfecta	11.3%
136	Rett Syndrome	11.1%
137	Classical Lissencephalies and Subcortical Band Heterotopias	11.1%
138	Menkes Kinky Hair Syndrome	11.1%
139	Mesoblastic Nephroma	11%
140	Renal Cell Carcinoma	11%
141	Papillary Renal Cell Carcinoma	11%
142	Tuberous Sclerosis	10.9%
143	Cystitis	10.6%
144	Ureteral obstruction	10.6%
145	Ureterocele	10.6%
146	Urethral Obstruction	10.6%
147	Urethritis	10.6%
148	Vesico-Ureteral Reflux	10.6%
149	Urinary Retention	10.6%
150	Denys-Drash Syndrome	10.5%
151	Familial Mediterranean Fever	10.5%
152	Twins, Conjoined	10.5%
153	Wiskott-Aldrich Syndrome	10.5%
154	Glomerulonephritis, Membranoproliferative	10.4%
155	Refsum Disease	10.4%
156	Klinefelter Syndrome	10.3%
157	Autoimmune Lymphoproliferative Syndrome	10.1%
158	Cryptorchidism	10%
159	Meconium Aspiration Syndrome	9.9%
160	Angioedemas, Hereditary	9.9%
161	Urinary Bladder Fistula	9.8%
162	Bladder Neoplasm	9.8%
163	Ureteral Neoplasms	9.8%
164	Urethral Neoplasms	9.8%
165	Sickle Cell Trait	9.7%
166	Pseudoxanthoma Elasticum	9.7%
167	Myotonic Dystrophy	9.5%
168	Scimitar Syndrome	9.4%
169	Neuronal Ceroid-Lipofuscinoses	9.4%
170	Adrenoleukodystrophy	9.4%
171	Acrocephalosyndactylia	9.2%
172	Bacteriuria	9.1%
173	Glycosuria	9.1%
174	Hematuria	9.1%
175	Oliguria	9.1%
176	Polyuria	9.1%
177	Proteinuria	9.1%
178	Pyuria	9.1%
179	Urinary Calculi	9.1%
180	Cystocele	9.1%
181	Urinary Incontinence	9.1%
182	Hyperkeratosis, Epidermolytic	9%
183	Microcephaly	8.9%
184	Macrocephaly	8.9%
185	Anti-Glomerular Basement Membrane Disease	8.9%
186	Xeroderma Pigmentosum	8.9%
187	Anophthalmos	8.9%
188	Anus, Imperforate	8.9%
189	Hydranencephaly	8.9%
190	Microphthalmos	8.9%
191	Neural Tube Defects	8.9%
192	Tethered Cord Syndrome	8.9%
193	Iniencephaly	8.9%
194	Craniorachischisis	8.9%
195	Limb Deformities, Congenital	8.9%
196	Exencephaly	8.9%
197	Septo-Optic Dysplasia	8.9%
198	Craniofacial Abnormalities	8.9%
199	Cortical Dysplasia	8.9%
200	Malformations of Cortical Development	8.9%
201	Anorectal Malformations	8.9%
202	Lupus Nephritis	8.9%
203	Abnormalities, Radiation-Induced	8.8%
204	Amino Acid Metabolism, Inborn Errors	8.8%
205	Carbohydrate Metabolism, Inborn Errors	8.8%
206	Metal Metabolism, Inborn Errors	8.8%
207	Progeria	8.8%
208	Lysosomal Storage Diseases	8.8%
209	Cytochrome-c Oxidase Deficiency	8.8%
210	Peroxisomal Disorders	8.8%
211	Atypical Hemolytic Uremic Syndrome	8.7%
212	Hepatolenticular Degeneration	8.7%
213	Craniosynostosis	8.7%
214	Syndactyly	8.7%
215	Brachycephaly	8.7%
216	Charcot-Marie-Tooth Disease	8.7%
217	Antley-Bixler Syndrome Phenotype	8.7%
218	Fabry Disease	8.6%
219	Familial Hypophosphatemic Rickets	8.3%
220	Amyloid Neuropathies, Familial	8.3%
221	Porencephaly	8.1%
222	Enuresis	8.1%
223	Hyperandrogenism	8.1%
224	Glycogen storage disease type II	8%
225	Gonadal Dysgenesis	8%
226	Adrenogenital Syndrome	8%
227	Ovotesticular Disorders of Sex Development	8%
228	Abdominal Cramps	8%
229	Amniotic Band Syndrome	8%
230	Asphyxia Neonatorum	8%
231	Infant, Premature, Diseases	8%
232	Infantile Colic	8%
233	Noonan Syndrome	7.9%
234	Acute Chest Syndrome	7.9%
235	Galactosemias	7.8%
236	Urea Cycle Disorders, Inborn	7.8%
237	Tyrosinemias	7.8%
238	Cleft Palate	7.8%
239	Blepharophimosis	7.7%
240	Laryngostenosis	7.7%
241	Mouth Abnormalities	7.7%
242	Chorioamnionitis	7.7%
243	Cutis Laxa	7.6%
244	Esophageal Atresia	7.6%
245	Intestinal Atresia	7.6%
246	Pectus excavatum	7.6%
247	Klippel-Feil Syndrome	7.6%
248	Retinitis Pigmentosa	7.6%
249	Gastroschisis	7.6%
250	Synostosis	7.6%
251	Pigmentary retinopathy	7.6%
252	Acrodermatitis	7.5%
253	Lymphangiectasis, Intestinal	7.5%
254	Porokeratosis	7.5%
255	Gianotti-Crosti Syndrome	7.5%
256	Keratoderma, Palmoplantar	7.5%
257	Chronic granulomatous disease	7.5%
258	Welander Distal Myopathy	7.4%
259	Jaw Abnormalities	7.3%
260	Ataxia Telangiectasia	7.3%
261	Poland Syndrome	7.2%
262	Mucopolysaccharidosis III	7.2%
263	Optic Atrophy, Hereditary, Leber	7.1%
264	Urethral Stenosis	7%
265	Urethral stricture	7%
266	Canavan Disease	7%
267	Alexander Disease	7%
268	Infertility	6.9%
269	Fetal Growth Retardation	6.9%
270	Fetal Hypoxia	6.9%
271	Fetal Alcohol Spectrum Disorders	6.9%
272	Deformity	6.8%
273	Genetic Diseases, Inborn	6.8%
274	Arthrogryposis	6.8%
275	Choanal Atresia	6.8%
276	Tracheobronchomegaly	6.8%
277	Laryngocele	6.8%
278	Choledochal Cyst	6.7%
279	Duane Retraction Syndrome	6.7%
280	Porphyrias, Hepatic	6.7%
281	Anemia, Neonatal	6.6%
282	Persistent Fetal Circulation Syndrome	6.6%
283	Central Nervous System Cysts	6.6%
284	Gaucher Disease	6.6%
285	Dandy-Walker Syndrome	6.6%
286	Umbilical hernia	6.6%
287	Peutz-Jeghers Syndrome	6.6%
288	Myotonia Congenita	6.6%
289	Thrombasthenia	6.6%
290	Antithrombin III Deficiency	6.6%
291	Protein C Deficiency	6.6%
292	Brain Diseases, Metabolic, Inborn	6.6%
293	Afibrinogenemia	6.5%
294	Dystonia Musculorum Deformans	6.5%
295	Factor VII Deficiency	6.5%
296	Factor X Deficiency	6.5%
297	Factor XII Deficiency	6.5%
298	Hemophilia A	6.5%
299	Activated Protein C Resistance	6.5%
300	Factor II deficiency	6.5%
301	Factor VIII Deficiency	6.5%
302	Factor V deficiency	6.5%
303	Factor XI Deficiency	6.5%
304	Hypoprothrombinemias	6.5%
305	Amelia	6.5%
306	Arachnodactyly	6.5%
307	Ectopia Cordis	6.5%
308	Ectromelia	6.5%
309	Hemimelia	6.5%
310	Meningomyelocele	6.5%
311	Phocomelia	6.5%
312	Sirenomelia	6.5%
313	Spina Bifida	6.5%
314	Polydactyly	6.5%
315	Brachydactyly	6.5%
316	Plagiocephaly	6.5%
317	Lower Extremity Deformities, Congenital	6.5%
318	Upper Extremity Deformities, Congenital	6.5%
319	Single umbilical artery	6.5%
320	Fanconi Anemia	6.5%
321	Homocystinuria	6.5%
322	Alkaptonuria	6.5%
323	Glycogen Storage Disease	6.5%
324	Hypophosphatasia	6.5%
325	Propionic acidemia	6.5%
326	Dihydropyrimidine Dehydrogenase Deficiency	6.5%
327	Cystinosis	6.5%
328	Lafora Disease	6.5%
329	Unverricht-Lundborg Syndrome	6.5%
330	Anemia, Diamond-Blackfan	6.5%
331	Leigh Disease	6.5%
332	Micrognathism	6.2%
333	Pierre Robin Syndrome	6.2%
334	Genital Diseases, Male	6.1%
335	Tay-Sachs Disease	6%
336	Albuminuria	6%
337	Hemoglobinuria	6%
338	Urge Incontinence	6%
339	Multiple Endocrine Neoplasia	6%
340	Laryngomalacia	6%
341	Pectus carinatum	6%
342	Urologic Neoplasms	5.9%
343	Congenital Hypothyroidism	5.9%
344	Dermatitis, Atopic	5.9%
345	Carbamoyl-Phosphate Synthase I Deficiency Disease	5.9%
346	Hydrops Fetalis	5.8%
347	Neonatal Abstinence Syndrome	5.8%
348	Pregnancy Complications	5.8%
349	Niemann-Pick Disease, Type C	5.8%
350	Congenital nystagmus	5.7%
351	Toxoplasmosis, Congenital	5.6%
352	Aortic coarctation	5.6%
353	Cor Triatriatum	5.6%
354	Coronary Vessel Anomalies	5.6%
355	Dental Enamel Hypoplasia	5.6%
356	Patent ductus arteriosus	5.6%
357	Ebstein Anomaly	5.6%
358	Heart Septal Defects	5.6%
359	Hypodontia	5.6%
360	Macrostomia	5.6%
361	Meningocele	5.6%
362	Microstomia	5.6%
363	Syphilis, Congenital	5.6%
364	Tetralogy of Fallot	5.6%
365	Transposition of Great Vessels	5.6%
366	Hypoplastic Left Heart Syndrome	5.6%
367	May-Thurner Syndrome	5.6%
368	Encephalocele	5.6%
369	Retrognathia	5.6%
370	Craniofacial Dysostosis	5.6%
371	Hypolipoproteinemias	5.6%
372	Papillon-Lefevre Disease	5.6%
373	Wolff-Parkinson-White Syndrome	5.6%
374	Hyperlipidemia, Familial Combined	5.6%
375	Hyperlipoproteinemia Type III	5.5%
376	Dermal Sinus	5.4%
377	Spina Bifida Cystica	5.4%
378	Spina Bifida Occulta	5.4%
379	Lissencephaly	5.4%
380	Polymicrogyria	5.4%
381	Pachygyria	5.4%
382	Schizencephaly	5.4%
383	Periventricular Nodular Heterotopia	5.4%
384	Glycogen Storage Disease Type I	5.4%
385	Glycogen Storage Disease Type V	5.4%
386	Sexually Transmitted Diseases	5.4%
387	Diurnal Enuresis	5.3%
388	Behcet Syndrome	5.3%
389	Genital Herpes	5.2%
390	Prognathism	5.2%
391	Congenital Hyperinsulinism	5%
392	Familial Periodic Paralysis	4.9%
393	Long QT Syndrome	4.9%
394	Platybasia	4.9%
395	Tricuspid Atresia	4.9%
396	Arrhythmogenic Right Ventricular Dysplasia	4.9%
397	Endometriosis	4.9%
398	Uterine Diseases	4.9%
399	Vaginal Diseases	4.9%
400	Vulvar Diseases	4.9%
401	Endometrioma	4.9%
402	Bronchomalacia	4.9%
403	Tracheomalacia	4.9%
404	Lactose Intolerance	4.9%
405	Variegate Porphyria	4.9%
406	Acute intermittent porphyria	4.9%
407	Porphyria Cutanea Tarda	4.9%
408	Hyperhomocysteinemia	4.9%
409	Hyperlipoproteinemia Type IV	4.8%
410	Hyperlipoproteinemia Type V	4.8%
411	Genital Neoplasms, Male	4.8%
412	Huntington Disease	4.8%
413	Vesicovaginal Fistula	4.7%
414	Aortopulmonary Septal Defect	4.6%
415	Double Outlet Right Ventricle	4.6%
416	Endocardial Cushion Defects	4.6%
417	Myocardial bridging	4.6%
418	Aorticopulmonary Septal Defect	4.6%
419	Hypoalphalipoproteinemias	4.6%
420	Paralysis, Obstetric	4.4%
421	Retinopathy of Prematurity	4.4%
422	Gout	4.4%
423	Multiple Endocrine Neoplasia Type 1	4.4%
424	Pseudohypoparathyroidism	4.4%
425	Bronchopulmonary Dysplasia	4.4%
426	Friedreich Ataxia	4.3%
427	Uterine Neoplasms	4.2%
428	Vaginal Neoplasms	4.2%
429	Vulvar Neoplasms	4.2%
430	Uterine Cancer	4.2%
431	Truncus Arteriosus, Persistent	4.1%
432	Goldenhar Syndrome	4.1%
433	Genital Neoplasms, Female	4.1%
434	Hypokalemic periodic paralysis	4.1%
435	Mandibulofacial Dysostosis	4.1%
436	Endometritis	4.1%
437	Romano-Ward Syndrome	4%
438	Adenomatous Polyposis Coli	4%
439	Ophthalmia Neonatorum	3.9%
440	Respiratory Distress Syndrome, Newborn	3.8%
441	Uterine Inversion	3.8%
442	Penile Neoplasms	3.7%
443	Prostatic Neoplasms	3.7%
444	Talipes	3.7%
445	Arthritis, Gouty	3.6%
446	Dyspareunia	3.5%
447	Fallopian Tube Neoplasms	3.5%
448	Congenital clubfoot	3.4%
449	Vertical Talus	3.4%
450	Epididymitis	3.3%
451	Penile Diseases	3.3%
452	Prostatic Diseases	3.3%
453	Spermatic Cord Torsion	3.3%
454	Hemospermia	3.3%
455	Testicular Hydrocele	3.3%
456	Uterine Rupture	3.3%
457	Leukomalacia, Periventricular	3.3%
458	Polycystic Kidney Diseases	3.3%
459	Nesidioblastosis	3.3%
460	Arteriovenous fistula	3.3%
461	Salpingitis	3.2%
462	Vulvovaginitis	3.2%
463	Polyhydramnios	3%
464	Obstetric Labor Complications	3%
465	Ectopic Pregnancy	3%
466	Pregnancy, Prolonged	3%
467	Puerperal Disorders	3%
468	Oligohydramnios	3%
469	Prenatal Injuries	3%
470	MELAS Syndrome	3%
471	Endometrial Hyperplasia	2.9%
472	Pyometra	2.9%
473	Vaginitis	2.9%
474	Vulvitis	2.9%
475	Vaginal Discharge	2.9%
476	Vulvodynia	2.9%
477	Hyaline Membrane Disease	2.8%
478	Testicular Diseases	2.8%
479	Varicocele	2.8%
480	Oophoritis	2.8%
481	Spermatocele	2.8%
482	Endometrial Neoplasms	2.8%
483	ovarian neoplasm	2.7%
484	Abruptio Placentae	2.7%
485	Placenta Accreta	2.7%
486	Kernicterus	2.7%
487	Pregnancy Complications, Cardiovascular	2.6%
488	Pregnancy Complications, Neoplastic	2.6%
489	Pregnancy Complications, Hematologic	2.5%
490	Pregnancy Complications, Infectious	2.5%
491	Fetal Death	2.5%
492	Perinatal death	2.5%
493	Ovarian Diseases	2.5%
494	Morning Sickness	2.5%
495	Adnexitis	2.5%
496	Pruritus Vulvae	2.5%
497	Uterine hemorrhage	2.5%
498	Vaginal Fistula	2.5%
499	Pelvic Inflammatory Disease	2.5%
500	Uterine Prolapse	2.4%
501	Vaginal Prolapse	2.4%
502	Uterine Cervical Incompetence	2.4%
503	Prostatic Neoplasms, Castration-Resistant	2.4%
504	Polycystic Kidney, Autosomal Dominant	2.4%
505	Carcinoma, Endometrioid	2.4%
506	Puerperal Infection	2.4%
507	Postpartum Hemorrhage	2.3%
508	Gestational Diabetes	2.1%
509	Candidiasis, Vulvovaginal	2.1%
510	Testicular Neoplasms	2%
511	Balanitis	2%
512	Benign prostatic hypertrophy	2%
513	Phimosis	2%
514	Priapism	2%
515	prostatitis	2%
516	Prostatic Adenoma	2%
517	Benign Prostatic Hyperplasia	2%
518	Prostatic Hypertrophy	2%
519	Prostatic Hyperplasia	2%
520	Uterine Cervicitis	1.9%
521	Leukorrhea	1.9%
522	Parametritis	1.9%
523	Chlamydia Infections	1.8%
524	Gonorrhea	1.8%
525	granulosa cell tumor	1.7%
526	Carcinoma, Ovarian Epithelial	1.7%
527	Premature Ejaculation	1.7%
528	Erectile dysfunction	1.7%
529	Bacterial Vaginosis	1.6%
530	Orchitis	1.6%
531	Abortion, Habitual	1.6%
532	Dystocia	1.6%
533	Eclampsia	1.6%
534	Fetal Membranes, Premature Rupture	1.6%
535	Placental Insufficiency	1.6%
536	Pre-Eclampsia	1.6%
537	Prenatal Exposure Delayed Effects	1.6%
538	HELLP Syndrome	1.6%
539	Placenta, Retained	1.6%
540	Trichomonas Vaginitis	1.6%
541	Uterine Perforation	1.6%
542	Ovarian Hyperstimulation Syndrome	1.6%
543	Syphilis	1.6%
544	Metrorrhagia	1.6%
545	Endometrial Stromal Sarcoma	1.5%
546	Abortion, Veterinary	1.4%
547	Pregnancy Complications, Parasitic	1.4%
548	Corpus Luteum Cyst	1.4%
549	Ovarian Cysts	1.4%
550	Anovulation	1.4%
551	Menorrhagia	1.4%
552	Premature Menopause	1.4%
553	Lactation Disorder	1.4%
554	Mastitis	1.4%
555	Depression, Postpartum	1.4%
556	Embryo Loss	1.4%
557	Fetal Resorption	1.4%
558	Hyperemesis Gravidarum	1.4%
559	Lymphogranuloma Venereum	1.3%
560	Azoospermia	1.3%
561	Oligospermia	1.3%
562	Impotence, Vasculogenic	1.3%
563	Asthenozoospermia	1.3%
564	Teratozoospermia	1.3%
565	Aspermia	1.3%
566	Trophoblastic Neoplasms	1.2%
567	Embolism, Amniotic Fluid	1.2%
568	Breech Presentation	1.2%
569	Stillbirth	1.2%
570	Polycystic Ovary Syndrome	1%
571	Premature Birth	1%
572	Leydig Cell Tumor	0.9%
573	Galactorrhea	0.8%
574	Choriocarcinoma	0.6%
575	Hydatidiform Mole	0.5%

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