MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Tuberous Sclerosis

(UMLS:C0041341)

Definition:: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
UMLS ID:: C0041341
MeSH ID:: D014402

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.445.810|C04.651.800|C04.700.700

Classification 2:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.500.507.400.750|C10.562.850|C10.574.500.865

Classification 3:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.666.507.400.750|C16.320.400.880|C16.320.700.700

Synonym(s)

Tuberous Sclerosis

Adenoma sebaceum syndrome

BOURNEVILLE-PRINGLE SYNDROME

Bourneville

Bourneville disease

Bourneville syndrome

Bourneville's Disease

Bourneville's disease

Bourneville-Brissaud disease

10.

Bourneville-Pringle syndrome

11.

Bourneville; phakomatosis

12.

EPILOIA

13.

Epiloia

14.

PHAKOMATOSIS, BOURNEVILLE

15.

Pringle

16.

Pringle disease

17.

TS - Tuberous sclerosis

18.

TSC

19.

TUBEROUS SCLEROSIS

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Everolimus	FAERS: 2	18495876	CTD US FAERS
2	Lamotrigine	FAERS: 2		US FAERS
3	Topiramate	FAERS: 2		US FAERS
4	Imatinib Mesylate	FAERS: 1		US FAERS
5	Levetiracetam	FAERS: 1		US FAERS
6	Oxcarbazepine	FAERS: 1		US FAERS
7	Phenytoin	FAERS: 1		US FAERS
8	Valproic Acid	FAERS: 1		US FAERS
9	Atazanavir Sulfate			OFFSIDES
10	Loratadine			OFFSIDES
11	Sirolimus		18495876 21115397	CTD OFFSIDES
12	Tenofovir			OFFSIDES
13	Vigabatrin		18479386	CTD
14	temsirolimus		16845661	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Multiple Endocrine Neoplasia	34.4%
2	Alstrom Syndrome	29.6%
3	Cockayne Syndrome	27.3%
4	Myotonic Dystrophy	26%
5	Aicardi's syndrome	25.8%
6	Dystonia Musculorum Deformans	25.7%
7	Basal Cell Nevus Syndrome	25.7%
8	Multiple Endocrine Neoplasia Type 1	25.6%
9	Hepatolenticular Degeneration	25%
10	Refsum Disease	24.9%
11	Charcot-Marie-Tooth Disease	24.7%
12	Canavan Disease	24.4%
13	Alexander Disease	24.4%
14	Lafora Disease	24.3%
15	Unverricht-Lundborg Syndrome	24.3%
16	Myotonia Congenita	23.2%
17	Neuronal Ceroid-Lipofuscinoses	22.8%
18	Amyloid Neuropathies, Familial	22.7%
19	Huntington Disease	22.6%
20	Classical Lissencephalies and Subcortical Band Heterotopias	22.5%
21	Nephroblastoma	22.4%
22	Microcephaly	21.8%
23	Macrocephaly	21.8%
24	Holoprosencephaly	21.7%
25	Central Nervous System Cysts	21.5%
26	Peutz-Jeghers Syndrome	21.4%
27	Fragile X Syndrome	21.3%
28	Paraneoplastic Encephalomyelitis	20.8%
29	Tuberous Sclerosis	20.8%
30	Adenomatous Polyposis Coli	20%
31	Smith-Magenis syndrome	20%
32	Adrenoleukodystrophy	20%
33	Myelitis, Transverse	19.7%
34	Lambert-Eaton Myasthenic Syndrome	19.4%
35	Dandy-Walker Syndrome	19.4%
36	Ataxia Telangiectasia	19.3%
37	Opsoclonus-Myoclonus Syndrome	19%
38	Menkes Kinky Hair Syndrome	18.6%
39	Friedreich Ataxia	18.6%
40	Optic Atrophy, Hereditary, Leber	18.2%
41	Optic Nerve Glioma	18%
42	Mucopolysaccharidosis II	17.8%
43	Limbic Encephalitis	17.7%
44	Cri-du-Chat Syndrome	17.5%
45	Down Syndrome	17.5%
46	Trisomy 21	17.5%
47	Multiple System Atrophy	17.5%
48	Nervous System Neoplasms	17.4%
49	Ichthyosis, X-Linked	17.3%
50	Medulloblastoma	17.2%
51	Acoustic Neuroma	17.1%
52	Dural Arteriovenous Fistula	16.9%
53	Hydranencephaly	16.9%
54	Neural Tube Defects	16.9%
55	Tethered Cord Syndrome	16.9%
56	Iniencephaly	16.9%
57	Craniorachischisis	16.9%
58	Exencephaly	16.9%
59	Septo-Optic Dysplasia	16.9%
60	Rett Syndrome	16.6%
61	Myasthenic Syndromes, Congenital	16.6%
62	Paraneoplastic Cerebellar Degeneration	16.6%
63	Amyotrophic Lateral Sclerosis	16.4%
64	Kartagener Syndrome	16.4%
65	Rubinstein-Taybi Syndrome	16.3%
66	Beckwith-Wiedemann Syndrome	16.2%
67	Wolf-Hirschhorn Syndrome	16.2%
68	Prader-Willi Syndrome	16.2%
69	Muscular Dystrophy, Duchenne	15.9%
70	CHARGE Syndrome	15.9%
71	Motor Neuron Disease	15.6%
72	Melanoma, Experimental	15.4%
73	Meningioma	15.4%
74	Subacute Combined Degeneration	15.3%
75	Albinism	15.2%
76	Denys-Drash Syndrome	15.2%
77	Cystic Fibrosis	15.1%
78	Carcinoma 256, Walker	14.8%
79	Nail-Patella Syndrome	14.7%
80	Neoplastic Syndromes, Hereditary	14.7%
81	Anencephaly	14.3%
82	Lewy Body Disease	14.3%
83	Muscular Dystrophy	14.3%
84	Sturge-Weber Syndrome	14.1%
85	Marfan Syndrome	14.1%
86	Parkinson Disease	13.9%
87	Ectodermal Dysplasia	13.9%
88	Aplasia Cutis Congenita	13.9%
89	Ophthalmoplegic Migraine	13.8%
90	Anemia, Sickle Cell	13.7%
91	Thalassemia	13.7%
92	Prion Diseases	13.6%
93	Neoplasms, Neuroepithelial	13.5%
94	Gliomatosis cerebri	13.5%
95	Williams Syndrome	13.4%
96	Stiff-Person Syndrome	13.4%
97	Progressive supranuclear palsy	13.4%
98	Spinal Muscular Atrophy	13.3%
99	Progressive Muscular Atrophy	13.3%
100	Neurofibrosarcoma	13.3%
101	Fabry Disease	13.2%
102	Restless Legs Syndrome	13.2%
103	Xeroderma Pigmentosum	13.1%
104	Lissencephaly	12.8%
105	Polymicrogyria	12.8%
106	Pachygyria	12.8%
107	Schizencephaly	12.8%
108	Periventricular Nodular Heterotopia	12.8%
109	Porencephaly	12.8%
110	Striatonigral Degeneration	12.8%
111	melanoma	12.6%
112	Polyradiculoneuropathy	12.6%
113	Polyradiculoneuritis	12.6%
114	Multiple Epiphyseal Dysplasia	12.6%
115	Osteochondrodysplasias	12.6%
116	Pelger-Huet Anomaly	12.6%
117	Werner Syndrome	12.6%
118	Neoplasms, Hormone-Dependent	12.5%
119	Paraneoplastic Syndromes	12.5%
120	Precancerous Conditions	12.5%
121	Neoplasms, Second Primary	12.5%
122	Pituitary Adenoma	12.4%
123	Pituitary Neoplasms	12.4%
124	Leukoencephalitis, Acute Hemorrhagic	12.2%
125	Smith-Lemli-Opitz Syndrome	12.1%
126	Carcinoma, Ehrlich Tumor	12.1%
127	Dermoid Cyst	12.1%
128	Carcinoma, Lewis Lung	12.1%
129	Choriocarcinoma	12%
130	Carcinoma, Lobular	12%
131	Retinoblastoma	11.9%
132	Miller Fisher Syndrome	11.9%
133	Trophoblastic Neoplasms	11.9%
134	Meningoencephalitis	11.9%
135	Leukemia, Experimental	11.9%
136	Mammary Neoplasms, Experimental	11.9%
137	Wiskott-Aldrich Syndrome	11.9%
138	Shy-Drager Syndrome	11.8%
139	Mobius Syndrome	11.8%
140	Sjogren-Larsson Syndrome	11.7%
141	Carcinoma, Pancreatic Ductal	11.7%
142	Adenoma, Acidophil	11.7%
143	Ganglioneuroma	11.7%
144	Glioma	11.7%
145	Malignant Glioma	11.7%
146	Dwarfism	11.7%
147	Brain Neoplasms	11.5%
148	Spinal Cord Neoplasms	11.5%
149	Central Nervous System Neoplasms	11.5%
150	Osteogenesis Imperfecta	11.5%
151	Guillain-Barre Syndrome	11.4%
152	Cyst	11.4%
153	Neoplastic Processes	11.4%
154	Pregnancy Complications, Neoplastic	11.4%
155	Neoplasms, Experimental	11.3%
156	Carcinoid Tumor	11.3%
157	Neurilemmoma	11.3%
158	Hutchinson's Melanotic Freckle	11.3%
159	Melanoma, Amelanotic	11.3%
160	Neuroectodermal Tumors	11.1%
161	Zellweger Syndrome	11.1%
162	Ocular Motility Disorders	11%
163	Cyclophoria	11%
164	Leukemia, Radiation-Induced	11%
165	Sarcoma, Experimental	11%
166	Neuromyelitis Optica	11%
167	Meningomyelocele	10.9%
168	Spina Bifida	10.9%
169	Polycystic Kidney Diseases	10.9%
170	Astrocytoma	10.8%
171	Ependymoma	10.8%
172	oligodendroglioma	10.8%
173	Ganglioglioma	10.8%
174	gliosarcoma	10.8%
175	Anaplastic astrocytoma	10.8%
176	Anaplastic Oligodendroglioma	10.8%
177	Vipoma	10.8%
178	Kallmann Syndrome	10.8%
179	Glycogen storage disease type II	10.8%
180	Cranial nerve diseases	10.7%
181	Demyelinating Diseases	10.7%
182	Demyelination	10.7%
183	Neuromuscular Diseases	10.7%
184	Chronobiology Disorders	10.7%
185	Autoimmune Lymphoproliferative Syndrome	10.6%
186	Malignant Carcinoid Syndrome	10.6%
187	Tauopathies	10.6%
188	Galactosemias	10.5%
189	Urea Cycle Disorders, Inborn	10.5%
190	Tyrosinemias	10.5%
191	Angioedemas, Hereditary	10.5%
192	Progressive bulbar palsy	10.5%
193	Bulbar palsy	10.5%
194	Glioblastoma	10.4%
195	Neuroblastoma	10.4%
196	Glioblastoma Multiforme	10.4%
197	Choledochal Cyst	10.4%
198	Duane Retraction Syndrome	10.4%
199	Neoplasms, Radiation-Induced	10.4%
200	Retinal Dysplasia	10.3%
201	Aniridia	10.2%
202	Ganglioneuroblastoma	10.2%
203	Cerebellar Neoplasms	10.2%
204	Carcinosarcoma	10.1%
205	Hemangiosarcoma	10.1%
206	Leukemia L1210	10.1%
207	Leukemia P388	10.1%
208	lymphangiosarcoma	10.1%
209	Acanthoma	10.1%
210	Epidermolysis Bullosa	10.1%
211	Pneumocephalus	10.1%
212	Poliomyelitis	10.1%
213	Leukoencephalopathy, Progressive Multifocal	10.1%
214	Sickle Cell Trait	10%
215	Meningocele	10%
216	Encephalocele	10%
217	Encephalomyelitis	9.9%
218	Autonomic Dysreflexia	9.9%
219	Complex Regional Pain Syndromes	9.9%
220	Trauma, Nervous System	9.9%
221	Primary Ciliary Dyskinesia	9.9%
222	Welander Distal Myopathy	9.8%
223	Neurologic Manifestations	9.8%
224	Neurotoxicity Syndromes	9.8%
225	Lupus Vasculitis, Central Nervous System	9.7%
226	Lymphomatoid Granulomatosis	9.7%
227	Sarcoma 180	9.7%
228	Carcinoid Heart Disease	9.6%
229	Dyskinesia, Drug-Induced	9.5%
230	Brain Diseases, Metabolic, Inborn	9.5%
231	Parathyroid Neoplasms	9.5%
232	Peritoneal Neoplasms	9.5%
233	Thyroid Neoplasm	9.5%
234	Thyroid carcinoma	9.5%
235	Liver Neoplasms, Experimental	9.4%
236	neurofibroma	9.4%
237	Supratentorial Neoplasms	9.4%
238	Epidural Abscess	9.3%
239	Olfactory Nerve Injuries	9.3%
240	Composite Lymphoma	9.3%
241	Thymoma	9.3%
242	Causalgia	9.3%
243	Leukemia, Plasma Cell	9.3%
244	Spinal Cord Injuries	9.2%
245	Basal cell carcinoma	9.2%
246	Carcinoma, Papillary	9.2%
247	Squamous cell carcinoma	9.2%
248	Chondrosarcoma	9.2%
249	Craniopharyngioma	9.2%
250	Cystadenoma	9.2%
251	leiomyosarcoma	9.2%
252	liposarcoma	9.2%
253	Mesothelioma	9.2%
254	synovial sarcoma	9.2%
255	Neuroectodermal Tumor, Melanotic	9.2%
256	Angiomyolipoma	9.2%
257	Clear Cell Sarcoma of Soft Tissue	9.2%
258	Alveolar Soft Part Sarcoma	9.2%
259	Neuroendocrine Tumors	9.2%
260	Sarcoma, Myeloid	9.2%
261	Carcinoma, Basal Cell	9.2%
262	Homocystinuria	9.2%
263	MPTP Poisoning	9.1%
264	Peripheral Nerve Injuries	9.1%
265	Leigh Disease	9.1%
266	Gaucher Disease	9.1%
267	Myasthenia Gravis	9.1%
268	Asterixis	9.1%
269	Ballismus	9.1%
270	Sleep Wake Disorders	9.1%
271	Prolactinoma	9%
272	Growth Hormone-Secreting Pituitary Adenoma	9%
273	Fetal Diseases	9%
274	Familial Mediterranean Fever	9%
275	Marchiafava-Bignami Disease	9%
276	insulinoma	9%
277	Encephalomyelitis, Acute Disseminated	8.9%
278	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	8.9%
279	Pseudoxanthoma Elasticum	8.9%
280	Pancreatic Neoplasm	8.8%
281	Gastrinoma	8.8%
282	Glucagonoma	8.8%
283	Scrapie	8.8%
284	Acute Chest Syndrome	8.8%
285	Presenile dementia	8.7%
286	Senile dementia	8.7%
287	Abnormalities, Drug-Induced	8.7%
288	Situs Inversus	8.7%
289	Cystadenocarcinoma	8.7%
290	Fibrosarcoma	8.7%
291	Osteosarcoma	8.7%
292	Mucoepidermoid Carcinoma	8.7%
293	Tracheal Neoplasms	8.7%
294	Facial Nerve Injuries	8.6%
295	Meningeal Neoplasms	8.6%
296	Leukoplakia, Oral	8.6%
297	Chronic Fatigue Syndrome	8.5%
298	Sleep Disorders, Circadian Rhythm	8.5%
299	Adenofibroma	8.5%
300	Fibroadenoma	8.5%
301	Malignant Fibrous Histiocytoma	8.5%
302	Familial Periodic Paralysis	8.5%
303	Xeroderma	8.4%
304	Botulism	8.3%
305	Hamartoma	8.3%
306	Neoplasms, Multiple Primary	8.3%
307	Tay-Sachs Disease	8.3%
308	Brain Stem Neoplasms	8.3%
309	MELAS Syndrome	8.2%
310	Bowen's Disease	8.2%
311	Paraganglioma	8.2%
312	Rhabdomyosarcoma	8.2%
313	Giant Cell Tumor of Bone	8.2%
314	Carbamoyl-Phosphate Synthase I Deficiency Disease	8.2%
315	Abdominal Neoplasms	8.2%
316	Erythroplasia	8.2%
317	Follicular cyst	8.2%
318	Head and Neck Neoplasms	8.2%
319	leukemia	8.2%
320	Mucocele	8.2%
321	Neoplasms, Germ Cell and Embryonal	8.2%
322	Neoplasms, Glandular and Epithelial	8.2%
323	Pilonidal Cyst	8.2%
324	Soft Tissue Neoplasms	8.2%
325	Thoracic Neoplasms	8.2%
326	Thyroglossal Cyst	8.2%
327	Synovial Cyst	8.2%
328	Germ Cell Cancer	8.2%
329	Aberrant Crypt Foci	8.2%
330	Neuroleptic Malignant Syndrome	8.2%
331	Myelinolysis, Central Pontine	8.2%
332	Leydig Cell Tumor	8.2%
333	Amino Acid Metabolism, Inborn Errors	8.2%
334	Carbohydrate Metabolism, Inborn Errors	8.2%
335	Metal Metabolism, Inborn Errors	8.2%
336	Progeria	8.2%
337	Lysosomal Storage Diseases	8.2%
338	Cytochrome-c Oxidase Deficiency	8.2%
339	Peroxisomal Disorders	8.2%
340	Niemann-Pick Disease, Type C	8.1%
341	Hyperphosphaturia	8.1%
342	Endometrial Stromal Sarcoma	8.1%
343	Meconium Aspiration Syndrome	8.1%
344	Eye Abnormalities	8.1%
345	Cardiovascular Abnormalities	8.1%
346	Myasthenia Gravis, Autoimmune, Experimental	8%
347	Myelitis	8%
348	Dermatofibrosarcoma	8%
349	Dermatofibrosarcoma Protuberans	8%
350	Skin Abnormalities	8%
351	Lymphatic Abnormalities	8%
352	Congenital Microtia	8%
353	Dermal Sinus	8%
354	Spina Bifida Cystica	8%
355	Spina Bifida Occulta	8%
356	Hydatidiform Mole	7.9%
357	Esophageal Neoplasms	7.9%
358	Leukomalacia, Periventricular	7.9%
359	Congenital diaphragmatic hernia	7.9%
360	Dementia, Vascular	7.8%
361	Brain Hemorrhage, Traumatic	7.8%
362	Pheochromocytoma	7.8%
363	Alveolar rhabdomyosarcoma	7.8%
364	Akathisia, Drug-Induced	7.8%
365	Thyroid Nodule	7.8%
366	Hepatocellular Adenoma	7.8%
367	Choroid Plexus Papilloma	7.7%
368	Hyperkeratosis, Epidermolytic	7.7%
369	Epilepsy, Post-Traumatic	7.7%
370	Lymphangioleiomyomatosis	7.7%
371	Polycystic Kidney, Autosomal Dominant	7.7%
372	Mucopolysaccharidosis III	7.6%
373	Digestive System Neoplasms	7.6%
374	Endocrine Gland Neoplasms	7.6%
375	Eye Neoplasms	7.6%
376	Turner Syndrome	7.6%
377	Horner Syndrome	7.5%
378	Cutis Laxa	7.5%
379	Retinitis Pigmentosa	7.5%
380	Congenital nystagmus	7.5%
381	Pigmentary retinopathy	7.5%
382	Bone neoplasms	7.5%
383	Leukoplakia	7.5%
384	Lymphocele	7.5%
385	Pancreatic Cyst	7.5%
386	Skin Neoplasms	7.5%
387	Hematologic Neoplasms	7.5%
388	Porokeratosis	7.5%
389	Keratoderma, Palmoplantar	7.5%
390	Chronic granulomatous disease	7.5%
391	Barrett Esophagus	7.4%
392	Breast Cyst	7.4%
393	Histiocytic Disorders, Malignant	7.4%
394	Actinic keratosis	7.4%
395	Mediastinal Cyst	7.4%
396	Neoplasm Invasiveness	7.4%
397	Neoplasm Metastasis	7.4%
398	Neoplasm Recurrence, Local	7.4%
399	Parovarian Cyst	7.4%
400	Pericardial Cyst	7.4%
401	Splenic Neoplasms	7.4%
402	Thymic Cyst	7.4%
403	Carcinogenesis	7.4%
404	Myxoid cyst	7.4%
405	Metastasis	7.4%
406	Testicular Neoplasms	7.4%
407	Urogenital Abnormalities	7.4%
408	Brain Injuries	7.3%
409	Multiple Sclerosis	7.3%
410	Meningeal Carcinomatosis	7.2%
411	Antley-Bixler Syndrome Phenotype	7.2%
412	Reflex Sympathetic Dystrophy	7.1%
413	Subdural Effusion	7.1%
414	Parkinsonian Disorders	7.1%
415	Nocturnal Myoclonus Syndrome	7.1%
416	Toxoplasmosis, Congenital	7%
417	Vasculitis, Central Nervous System	7%
418	Jet Lag Syndrome	7%
419	Mesoblastic Nephroma	7%
420	Deformity	6.9%
421	Porphyrias, Hepatic	6.9%
422	Thrombasthenia	6.9%
423	Antithrombin III Deficiency	6.9%
424	Protein C Deficiency	6.9%
425	Afibrinogenemia	6.9%
426	Factor VII Deficiency	6.9%
427	Factor X Deficiency	6.9%
428	Factor XII Deficiency	6.9%
429	Hemophilia A	6.9%
430	Activated Protein C Resistance	6.9%
431	Factor II deficiency	6.9%
432	Factor VIII Deficiency	6.9%
433	Factor V deficiency	6.9%
434	Factor XI Deficiency	6.9%
435	Hypoprothrombinemias	6.9%
436	Fanconi Anemia	6.8%
437	Cortical Dysplasia	6.8%
438	Malformations of Cortical Development	6.8%
439	Anemia, Diamond-Blackfan	6.8%
440	Lymphoma	6.8%
441	Brain Abscess	6.8%
442	Corpus Luteum Cyst	6.8%
443	Ophthalmoplegia	6.8%
444	Ovarian Cysts	6.8%
445	External Ophthalmoplegia	6.8%
446	Maxillofacial Abnormalities	6.8%
447	Dextrocardia	6.7%
448	Hypokalemic periodic paralysis	6.7%
449	Carotid Artery Injuries	6.7%
450	granulosa cell tumor	6.7%
451	Carcinoma, Ovarian Epithelial	6.7%
452	Klinefelter Syndrome	6.6%
453	POEMS Syndrome	6.6%
454	Central Cord Syndrome	6.5%
455	Brain Diseases	6.5%
456	Dysautonomia	6.5%
457	Meningitis	6.5%
458	Movement Disorders	6.5%
459	Pachymeningitis	6.5%
460	Spinal Cord Diseases	6.5%
461	Vagus Nerve Disorder	6.5%
462	Glossopharyngeal Neuralgia	6.5%
463	Abducens Nerve Diseases	6.5%
464	Heavy Metal Poisoning, Nervous System	6.5%
465	Neuromuscular Junction Diseases	6.5%
466	Trochlear Nerve Diseases	6.5%
467	Peripheral Nervous System Diseases	6.5%
468	Meningitis, Bacterial	6.5%
469	Meningitis, Fungal	6.5%
470	Chorea	6.5%
471	Acrodynia	6.4%
472	Adrenocortical carcinoma	6.4%
473	Congenital Hypothyroidism	6.4%
474	Tuberculosis, Meningeal	6.4%
475	Dermatitis, Atopic	6.4%
476	Nose Neoplasms	6.4%
477	Palatal Neoplasms	6.4%
478	Vocal Cord Paralysis	6.3%
479	Frontotemporal dementia	6.3%
480	Alice in Wonderland Syndrome	6.1%
481	Abnormalities, Radiation-Induced	6.1%
482	Meige Syndrome	6.1%
483	Brachial Plexus Neuritis	6.1%
484	Neuralgic Amyotrophy	6.1%
485	Cerebral Ventriculitis	6.1%
486	Adenoma	6.1%
487	Ameloblastoma	6.1%
488	Angiokeratoma	6.1%
489	Carcinoma	6.1%
490	Chordoma	6.1%
491	Hemangioma	6.1%
492	hemangiopericytoma	6.1%
493	Lymphangioma	6.1%
494	Mesenchymoma	6.1%
495	Nevus	6.1%
496	Retroperitoneal Neoplasms	6.1%
497	Teratoma	6.1%
498	Hepatoblastoma	6.1%
499	Mixed Tumor, Mullerian	6.1%
500	Germinoma	6.1%
501	Teratocarcinoma	6.1%
502	Angiofibroma	6.1%
503	Sarcoma	6.1%
504	Epithelioma	6.1%
505	Central Nervous System Infection	6%
506	Myopathy	6%
507	Optic Neuropathy	6%
508	Brain Concussion	6%
509	Amblyopia	6%
510	Alkaptonuria	6%
511	Glycogen Storage Disease	6%
512	Hypophosphatasia	6%
513	Propionic acidemia	6%
514	Dihydropyrimidine Dehydrogenase Deficiency	6%
515	Cystinosis	6%
516	Renal Cell Carcinoma	6%
517	Papillary Renal Cell Carcinoma	6%
518	Behcet Syndrome	6%
519	Cerebrospinal Fluid Otorrhea	5.9%
520	Cerebrospinal Fluid Rhinorrhea	5.9%
521	Neuritis, Autoimmune, Experimental	5.9%
522	Toxoplasmosis, Cerebral	5.9%
523	Facial Nerve Diseases	5.9%
524	Craniocerebral Trauma	5.9%
525	Parasomnia	5.9%
526	Dyssomnias	5.9%
527	Gait Ataxia	5.9%
528	Scimitar Syndrome	5.9%
529	Vestibulocochlear Nerve Diseases	5.9%
530	Decerebrate State	5.9%
531	Hemiparesis	5.9%
532	Meningism	5.9%
533	Paresis	5.9%
534	Seizures	5.9%
535	Sensation Disorders	5.9%
536	Complex partial seizures	5.9%
537	Monoparesis	5.9%
538	Neurogenic Inflammation	5.9%
539	Gait Disorders, Neurologic	5.9%
540	Neuromuscular Manifestations	5.9%
541	Sweating, Gustatory	5.9%
542	Auriculotemporal Syndrome	5.9%
543	Brain Death	5.8%
544	Coma, Post-Head Injury	5.8%
545	Alcohol Withdrawal Seizures	5.8%
546	Carcinoma, Endometrioid	5.8%
547	Nasopharyngeal carcinoma	5.8%
548	Tarsal Tunnel Syndrome	5.7%
549	Cauda Equina Syndrome	5.7%
550	Posterior Leukoencephalopathy Syndrome	5.7%
551	Posterior reversible encephalopathy syndrome	5.7%
552	Abdominal Cramps	5.6%
553	Amniotic Band Syndrome	5.6%
554	Asphyxia Neonatorum	5.6%
555	Infant, Premature, Diseases	5.6%
556	Infantile Colic	5.6%
557	Creutzfeldt-Jakob disease	5.6%
558	Basal Ganglia Cerebrovascular Disease	5.6%
559	Brain Injuries, Diffuse	5.6%
560	Traumatic Brain Injury	5.6%
561	Cerebellar Ataxia	5.6%
562	Torticollis	5.6%
563	Multiple Sclerosis, Chronic Progressive	5.6%
564	Multiple Sclerosis, Relapsing-Remitting	5.6%
565	Mouth Neoplasms	5.6%
566	Vascular Neoplasms	5.6%
567	Thymus Neoplasms	5.6%
568	Hydrops Fetalis	5.6%
569	Genital Neoplasms, Female	5.5%
570	Pancreatic Pseudocyst	5.5%
571	Plasmacytoma	5.5%
572	Acrocephalosyndactylia	5.5%
573	Malignant histiocytosis	5.5%
574	Lymphatic Metastasis	5.5%
575	Neoplasms, Unknown Primary	5.5%
576	Leukemic Infiltration	5.5%
577	Breast Neoplasms, Male	5.5%
578	Histiocytic sarcoma	5.5%
579	Neoplasm Micrometastasis	5.5%
580	Triple Negative Breast Neoplasms	5.5%
581	Akathisia	5.5%
582	Restlessness	5.5%
583	Psychomotor Agitation	5.5%
584	Pupil Disorders	5.5%
585	Neurobehavioral Manifestations	5.5%
586	Basal Ganglia Hemorrhage	5.5%
587	Hypolipoproteinemias	5.5%
588	Papillon-Lefevre Disease	5.5%
589	Hyperlipidemia, Familial Combined	5.4%
590	Hyperlipoproteinemia Type III	5.4%
591	Uveomeningoencephalitic Syndrome	5.4%
592	Vertigo	5.4%
593	Alcohol-Induced Disorders, Nervous System	5.4%
594	Nelson Syndrome	5.4%
595	Subarachnoid Hemorrhage, Traumatic	5.3%
596	Carotid Artery, Internal, Dissection	5.3%
597	Prune Belly Syndrome	5.3%
598	Twins, Conjoined	5.3%
599	Waardenburg Syndrome	5.3%
600	Myoclonic Epilepsy	5.2%
601	Epilepsy, Temporal Lobe	5.2%
602	Epilepsy, Rolandic	5.2%
603	Benign Rolandic Epilepsy	5.2%
604	Subacute Sclerosing Panencephalitis	5.2%
605	Carpal Tunnel Syndrome	5.2%
606	Vascular Headaches	5.2%
607	Hypoxia-Ischemia, Brain	5.2%
608	Sciatica	5.2%
609	Tardive Dyskinesia	5.2%
610	Persistent Vegetative State	5.2%
611	Vertebral Artery Dissection	5.1%
612	Adrenal Gland Neoplasms	5.1%
613	Gastrointestinal Neoplasms	5.1%
614	Genital Neoplasms, Male	5.1%
615	Liver neoplasms	5.1%
616	Uveal Neoplasms	5.1%
617	Amnesia, Transient Global	5.1%
618	Gait Apraxia	5.1%
619	Anemia, Neonatal	5.1%
620	Persistent Fetal Circulation Syndrome	5.1%
621	Urologic Neoplasms	5.1%
622	Umbilical hernia	5.1%
623	Sebaceous Gland Neoplasms	5.1%
624	Spinal Neoplasms	5.1%
625	Bone Marrow Neoplasms	5.1%
626	Adenocarcinoma	5.1%
627	Carcinoma in Situ	5.1%
628	Carcinoma, Transitional Cell	5.1%
629	Phyllodes Tumor	5.1%
630	Dysgerminoma	5.1%
631	Hemangioendothelioma	5.1%
632	Lipoma	5.1%
633	Myoma	5.1%
634	Myxoma	5.1%
635	Neuroma	5.1%
636	Papilloma	5.1%
637	Pseudomyxoma Peritonei	5.1%
638	Seminoma	5.1%
639	Papillomatosis	5.1%
640	Angiolipoma	5.1%
641	Myelolipoma	5.1%
642	Neoplasms, Bone Tissue	5.1%
643	Neoplasms, Fibrous Tissue	5.1%
644	Smooth Muscle Tumor	5.1%
645	Adenomatosis, Pulmonary	5.1%
646	Adenomatous Polyps	5.1%
647	Carcinoma, Large Cell	5.1%
648	Carcinoma, Small Cell	5.1%
649	Desmoplastic Small Round Cell Tumor	5.1%
650	Chondroma	5.1%
651	Enchondroma	5.1%
652	Hodgkin Disease	5%
653	Lymphoma, Non-Hodgkin	5%
654	Polycystic Ovary Syndrome	5%
655	Lactose Intolerance	5%
656	Variegate Porphyria	5%
657	Acute intermittent porphyria	5%
658	Porphyria Cutanea Tarda	5%
659	Putaminal Hemorrhage	5%
660	Craniosynostosis	5%
661	Syndactyly	5%
662	Brachycephaly	5%
663	Hyperhomocysteinemia	5%
664	Voice Disorders	5%
665	Voice Disturbance	5%
666	Renal Aminoacidurias	5%
667	Fanconi Syndrome	5%
668	Pseudohypoaldosteronism	5%
669	Liddle Syndrome	5%
670	Hyperlipoproteinemia Type IV	5%
671	Hyperlipoproteinemia Type V	5%
672	Familial Hypophosphatemic Rickets	5%
673	Infarction, Middle Cerebral Artery	4.9%
674	Infarction, Anterior Cerebral Artery	4.9%
675	Infarction, Posterior Cerebral Artery	4.9%
676	Glycogen Storage Disease Type I	4.9%
677	Glycogen Storage Disease Type V	4.9%
678	Anophthalmos	4.8%
679	Anus, Imperforate	4.8%
680	Microphthalmos	4.8%
681	Limb Deformities, Congenital	4.8%
682	Craniofacial Abnormalities	4.8%
683	Anorectal Malformations	4.8%
684	Mitochondrial Encephalomyopathies	4.8%
685	Bloom Syndrome	4.8%
686	Meningitis, Cryptococcal	4.8%
687	Meningitis, Listeria	4.8%
688	Meningitis, Haemophilus	4.7%
689	Meningitis, Pneumococcal	4.7%
690	Cubital Tunnel Syndrome	4.7%
691	Diffuse Axonal Injury	4.7%
692	Neonatal Abstinence Syndrome	4.7%
693	Juvenile Myoclonic Epilepsy	4.7%
694	Myoclonic Epilepsies, Progressive	4.7%
695	Noonan Syndrome	4.7%
696	Gout	4.7%
697	Pseudohypoparathyroidism	4.7%
698	Fetal Growth Retardation	4.7%
699	Primary amyloidosis	4.7%
700	Fetal Hypoxia	4.7%
701	Fetal Alcohol Spectrum Disorders	4.7%
702	Cleft Palate	4.7%
703	Renal tubular acidosis	4.6%
704	Syphilis, Congenital	4.6%
705	Kernicterus	4.6%
706	Leukemia, Myelomonocytic, Chronic	4.6%
707	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	4.6%
708	Reflex, Abnormal	4.6%
709	Hyporeflexia	4.6%
710	Hyperreflexia	4.6%
711	Adenoid Cystic Carcinoma	4.6%
712	fibroma	4.6%
713	Fibromatosis	4.6%
714	Osteoblastoma	4.6%
715	Osteoma	4.6%
716	Rhabdomyoma	4.6%
717	Chondromatosis	4.6%
718	Adenocarcinoma, Clear Cell	4.6%
719	Cholangiocarcinoma	4.6%
720	Cervical Intraepithelial Neoplasia	4.6%
721	Hemangioblastoma	4.6%
722	Lymphoma, Extranodal NK-T-Cell	4.6%
723	Giant Cell Arteritis	4.5%
724	Temporal Arteritis	4.5%
725	West Nile Fever	4.5%
726	Hypoalphalipoproteinemias	4.5%
727	Auditory Perceptual Disorders	4.5%
728	Kearns-Sayre syndrome	4.4%
729	Blepharophimosis	4.4%
730	Laryngostenosis	4.4%
731	Mouth Abnormalities	4.4%
732	Akinetic Mutism	4.4%
733	Anoxic Encephalopathy	4.4%
734	Arachnoiditis	4.4%
735	Basal Ganglia Diseases	4.4%
736	Brain Damage, Chronic	4.4%
737	Cerebellar Diseases	4.4%
738	Encephalitis	4.4%
739	Encephalomalacia	4.4%
740	Epilepsy	4.4%
741	Hydrocephalus	4.4%
742	Congenital Hydrocephalus	4.4%
743	Hypothalamic Diseases	4.4%
744	Aseptic Meningitis	4.4%
745	Neuritis	4.4%
746	Polyneuritis	4.4%
747	Radiculitis	4.4%
748	Syringomyelia	4.4%
749	Thalamic Diseases	4.4%
750	Intracranial Hypertension	4.4%
751	Polyneuropathy	4.4%
752	Mononeuritis	4.4%
753	Aura	4.4%
754	Leukoencephalopathy	4.4%
755	Essential Tremor	4.4%
756	Neuroaxonal Dystrophies	4.4%
757	Familial Tremor	4.4%
758	Headache Disorders	4.4%
759	Mononeuropathies	4.4%
760	Intracranial Hypotension	4.4%
761	Brachial Plexus Neuropathies	4.4%
762	Radiculopathy	4.4%
763	Mononeuropathy Multiplex	4.4%
764	Nerve Root Compression	4.4%
765	Brain Edema	4.4%
766	Brain Hypoxia	4.4%
767	Aqueductal Stenosis	4.4%
768	Pneumorrhachis	4.4%
769	Writer's Cramp	4.4%
770	Pituitary Apoplexy	4.4%
771	Esophageal Atresia	4.4%
772	Intestinal Atresia	4.4%
773	Horseshoe Kidney	4.4%
774	Pectus excavatum	4.4%
775	Klippel-Feil Syndrome	4.4%
776	Gastroschisis	4.4%
777	Synostosis	4.4%
778	Acrodermatitis	4.4%
779	Lymphangiectasis, Intestinal	4.4%
780	Gianotti-Crosti Syndrome	4.4%
781	Brain Contusion	4.4%
782	Brain Infarction	4.4%
783	ovarian neoplasm	4.3%
784	Congenital Hyperinsulinism	4.3%
785	Fibromatosis, Aggressive	4.3%
786	Fibromatosis, Abdominal	4.3%
787	Klatskin Tumor	4.3%
788	Chorioamnionitis	4.3%
789	Ear Neoplasms	4.3%
790	Eyelid Neoplasms	4.3%
791	Lung Neoplasms	4.3%
792	Pleural Neoplasms	4.3%
793	Mastocytosis	4.2%
794	Cell Transformation, Viral	4.2%
795	Salivary Gland Neoplasms	4.2%
796	Tongue Neoplasms	4.2%
797	Gastrointestinal Stromal Tumors	4.2%
798	Hemangioma, Cavernous	4.2%
799	Leukemia, T-Cell	4.2%
800	Uterine Neoplasms	4.2%
801	Vaginal Neoplasms	4.2%
802	Vulvar Neoplasms	4.2%
803	Uterine Cancer	4.2%
804	Leukemia, B-Cell	4.2%
805	Fallopian Tube Neoplasms	4.2%
806	Lymphoma, Follicular	4.2%
807	T-Cell Lymphoma	4.2%
808	Mantle cell lymphoma	4.2%
809	Jaw Abnormalities	4.2%
810	Mastocytoma	4.1%
811	Mastocytosis, Systemic	4.1%
812	Leukemia, Myeloid, Chronic-Phase	4.1%
813	Arthrogryposis	4.1%
814	Choanal Atresia	4.1%
815	Tracheobronchomegaly	4.1%
816	Laryngocele	4.1%
817	Cystinuria	4.1%
818	Hermaphroditism	4.1%
819	Disorders of Sex Development	4.1%
820	Cryptorchidism	4.1%
821	Hypospadias	4.1%
822	Glycosuria, Renal	4%
823	Alexia	4%
824	Dyslexia	4%
825	Waldenstrom Macroglobulinemia	4%
826	Multiple Myeloma	4%
827	Brain Diseases, Metabolic	4%
828	Cerebrovascular Disorders	4%
829	Myositis	4%
830	Optic Atrophy	4%
831	Optic Neuritis	4%
832	Papilledema	4%
833	Strabismus	4%
834	Tolosa-Hunt Syndrome	4%
835	Cerebrovascular Insufficiency	4%
836	Isaacs syndrome	4%
837	Arsenic Poisoning	4%
838	Dementia	4%
839	Myotonic Disorders	4%
840	Central Nervous System Fungal Infections	4%
841	Conus Medullaris Syndrome	4%
842	Spinal Cord Vascular Diseases	4%
843	Diabetic Neuropathies	4%
844	Facial Injuries	4%
845	Facial Neuralgia	4%
846	Diabetic Amyotrophy	4%
847	Diabetic Autonomic Neuropathy	4%
848	Sleep Talking	4%
849	Manganese Poisoning	4%
850	Sleep Disorders, Intrinsic	4%
851	Orthostatic intolerance	4%
852	Anosmia	4%
853	Ataxia	4%
854	Athetosis	4%
855	Catalepsy	4%
856	Dystonia	4%
857	Hemiplegia	4%
858	Locked-In Syndrome	4%
859	Muscle Hypertonia	4%
860	Muscle hypotonia	4%
861	Myoclonus	4%
862	Myotonia	4%
863	Neuralgia	4%
864	Paraplegia	4%
865	Pseudobulbar Palsy	4%
866	Quadriplegia	4%
867	Spasm	4%
868	Spastic Paraplegia	4%
869	Status Epilepticus	4%
870	Taste Disorders	4%
871	Tremor	4%
872	Monoplegia	4%
873	Hypokinesia	4%
874	Paraparesis	4%
875	Bradykinesia	4%
876	Waxy flexibility	4%
877	Action Tremor	4%
878	Resting Tremor	4%
879	Dysosmia	4%
880	Quadriparesis	4%
881	Mercury Poisoning, Nervous System	4%
882	Olfaction Disorders	4%
883	Myokymia	4%
884	Lead Poisoning, Nervous System	4%
885	Vestibular Neuronitis	4%
886	Somatosensory Disorders	4%
887	Neuropathic pain	4%
888	Hyperkinesia	4%
889	Intention tremor	4%
890	Cerebral Infarction	4%
891	Brain Stem Infarctions	4%
892	Pharyngeal Neoplasms	4%
893	Hematoma, Subdural	3.9%
894	Hematoma, Epidural, Cranial	3.9%
895	Bile Duct Neoplasms	3.9%
896	gallbladder neoplasm	3.9%
897	Intestinal Neoplasms	3.9%
898	Penile Neoplasms	3.9%
899	Prostatic Neoplasms	3.9%
900	Stomach Neoplasms	3.9%
901	Moyamoya Disease	3.9%
902	Polycythemia Vera	3.9%
903	Arthritis, Gouty	3.8%
904	Bronchial Neoplasms	3.8%
905	Poland Syndrome	3.8%
906	Laryngomalacia	3.8%
907	Multiple Pulmonary Nodules	3.8%
908	Pectus carinatum	3.8%
909	Zollinger-Ellison syndrome	3.8%
910	Lateral Medullary Syndrome	3.8%
911	Endometrial Neoplasms	3.8%
912	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.8%
913	Leukemia, Large Granular Lymphocytic	3.8%
914	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.8%
915	Lymphoma, T-Cell, Cutaneous	3.8%
916	Lymphoma, AIDS-Related	3.8%
917	Enteropathy-Associated T-Cell Lymphoma	3.8%
918	Primary Effusion Lymphoma	3.8%
919	Hand-Arm Vibration Syndrome	3.8%
920	Bladder Exstrophy	3.7%
921	Epispadias	3.7%
922	Multicystic Dysplastic Kidney	3.7%
923	Vision Disorders	3.7%
924	Metamorphopsia	3.7%
925	Visual Impairment	3.7%
926	Fibromyalgia	3.7%
927	Optic Neuropathy, Ischemic	3.7%
928	Anterior Ischemic Optic Neuropathy	3.7%
929	Central Nervous System Bacterial Infections	3.7%
930	Medial Tibial Stress Syndrome	3.7%
931	Facial Hemiatrophy	3.7%
932	Melkersson-Rosenthal Syndrome	3.7%
933	Mitochondrial Myopathies	3.7%
934	Laryngeal neoplasm	3.7%
935	Ophthalmia Neonatorum	3.7%
936	Anisocoria	3.7%
937	Confusion	3.7%
938	Facial paralysis	3.7%
939	Lethargy	3.7%
940	Memory Disorders	3.7%
941	Muscle Cramp	3.7%
942	Perceptual Disorders	3.7%
943	Psychomotor Disorders	3.7%
944	Tonic Pupil	3.7%
945	Eosinophilia-Myalgia Syndrome	3.7%
946	Anhedonia	3.7%
947	Disorientation	3.7%
948	Facial Paresis	3.7%
949	Memory Loss	3.7%
950	Hemisensory Neglect	3.7%
951	Dysacusis	3.7%
952	Sleep Bruxism	3.7%
953	Muscular Atrophy	3.7%
954	Respiratory Paralysis	3.7%
955	Tetany	3.6%
956	Dupuytren Contracture	3.6%
957	Bladder Neoplasm	3.6%
958	Kidney Neoplasm	3.6%
959	Ureteral Neoplasms	3.6%
960	Urethral Neoplasms	3.6%
961	Urticaria Pigmentosa	3.6%
962	Mycosis Fungoides	3.5%
963	Lymphomatoid Papulosis	3.5%
964	Plasmablastic lymphoma	3.5%
965	Hypopharyngeal Neoplasms	3.5%
966	Pleural Effusion, Malignant	3.5%
967	Hypopharyngeal Cancer	3.5%
968	Hematoma, Subdural, Intracranial	3.5%
969	Hematoma, Subdural, Chronic	3.5%
970	Hematoma, Subdural, Acute	3.5%
971	Parotid Neoplasms	3.5%
972	Prostatic Neoplasms, Castration-Resistant	3.5%
973	Consciousness Disorders	3.4%
974	Mental Retardation	3.4%
975	Muscle Weakness	3.4%
976	Depressed Level of Consciousness	3.4%
977	Mental deficiency	3.4%
978	Intellectual Disability	3.4%
979	Bell Palsy	3.4%
980	Catatonia	3.4%
981	Herpes Zoster Oticus	3.4%
982	Cerebral Palsy	3.4%
983	Epilepsies, Partial	3.4%
984	Epilepsy, Generalized	3.4%
985	Pseudotumor Cerebri	3.4%
986	Sciatic Neuropathy	3.4%
987	Hypertensive Encephalopathy	3.4%
988	Ulnar Neuropathies	3.4%
989	Lesion of Sciatic Nerve	3.4%
990	Simple Partial Seizures	3.4%
991	Epilepsy, Reflex	3.4%
992	Ulnar Neuritis	3.4%
993	Radial nerve compression	3.4%
994	Radial Tunnel Syndrome	3.4%
995	Peroneal Neuropathies	3.4%
996	Radial Neuropathy	3.4%
997	Median Neuropathy	3.4%
998	Sciatic Nerve Palsy	3.4%
999	Femoral Neuropathy	3.4%
1000	Tibial Neuropathy	3.4%
1001	Ulnar Nerve Palsy	3.4%
1002	Postural Orthostatic Tachycardia Syndrome	3.4%
1003	Radial nerve palsy	3.4%
1004	Headache Disorders, Primary	3.4%
1005	Headache Disorders, Secondary	3.4%
1006	Medication overuse headache	3.4%
1007	Aphonia	3.4%
1008	Sleep Deprivation	3.4%
1009	Dysphonia	3.4%
1010	Micrognathism	3.3%
1011	Pierre Robin Syndrome	3.3%
1012	Tonsillar Neoplasms	3.3%
1013	Paralysis, Obstetric	3.3%
1014	Retinopathy of Prematurity	3.3%
1015	Amelia	3.2%
1016	Arachnodactyly	3.2%
1017	Bronchopulmonary Dysplasia	3.2%
1018	Ectopia Cordis	3.2%
1019	Ectromelia	3.2%
1020	Hemimelia	3.2%
1021	Phocomelia	3.2%
1022	Sirenomelia	3.2%
1023	Polydactyly	3.2%
1024	Brachydactyly	3.2%
1025	Plagiocephaly	3.2%
1026	Lower Extremity Deformities, Congenital	3.2%
1027	Upper Extremity Deformities, Congenital	3.2%
1028	Single umbilical artery	3.2%
1029	Cecal Neoplasms	3.2%
1030	Duodenal Neoplasms	3.2%
1031	Burkitt Lymphoma	3.2%
1032	Pituitary Diseases	3.1%
1033	Myalgia	3.1%
1034	Hyperandrogenism	3.1%
1035	Thoracic Outlet Syndrome	3.1%
1036	Carotid Artery Diseases	3.1%
1037	Brain Ischemia	3.1%
1038	Esotropia	3.1%
1039	Exotropia	3.1%
1040	Hypotension, Orthostatic	3.1%
1041	Sleep Apnea Syndromes	3.1%
1042	Cerebrovascular accident	3.1%
1043	Polymyositis	3.1%
1044	Kluver-Bucy Syndrome	3.1%
1045	Vasospasm, Intracranial	3.1%
1046	Spinal Cord Ischemia	3.1%
1047	Intracranial Arterial Diseases	3.1%
1048	Post-Exercise Hypotension	3.1%
1049	Retrognathia	3.1%
1050	Disorders of Excessive Somnolence	3.1%
1051	Sleep Initiation and Maintenance Disorders	3.1%
1052	Night Terrors	3.1%
1053	Somnambulism	3.1%
1054	Trigeminal Nerve Disorder	3.1%
1055	Transient Insomnia	3.1%
1056	Sleep Paralysis	3.1%
1057	Chronic Insomnia	3.1%
1058	REM Sleep Behavior Disorder	3.1%
1059	Hypersomnia	3.1%
1060	Dysgeusia	3.1%
1061	Formication	3.1%
1062	Hyperalgesia	3.1%
1063	Hyperesthesia	3.1%
1064	Hypesthesia	3.1%
1065	Language Disorders	3.1%
1066	Numbness	3.1%
1067	Paresthesia	3.1%
1068	Paraparesis, Spastic	3.1%
1069	Trismus	3.1%
1070	Epilepsia Partialis Continua	3.1%
1071	Hypogeusia	3.1%
1072	Brown-Sequard Syndrome	3.1%
1073	Lockjaw	3.1%
1074	Allodynia	3.1%
1075	Lead Poisoning, Nervous System, Childhood	3.1%
1076	Lead Poisoning, Nervous System, Adult	3.1%
1077	Ageusia	3.1%
1078	Tuberculosis, Central Nervous System	3.1%
1079	Sezary Syndrome	3%
1080	Radicular Cyst	3%
1081	Nasopharyngeal Neoplasms	3%
1082	Appendiceal Neoplasms	3%
1083	Colonic Neoplasms	3%
1084	Rectal Neoplasms	3%
1085	Respiratory Distress Syndrome, Newborn	3%
1086	Colorectal Neoplasms	3%
1087	Waterhouse-Friderichsen Syndrome	3%
1088	Aortic coarctation	3%
1089	Cor Triatriatum	3%
1090	Coronary Vessel Anomalies	3%
1091	Dental Enamel Hypoplasia	3%
1092	Patent ductus arteriosus	3%
1093	Ebstein Anomaly	3%
1094	Heart Septal Defects	3%
1095	Hypodontia	3%
1096	Macrostomia	3%
1097	Microstomia	3%
1098	Tetralogy of Fallot	3%
1099	Transposition of Great Vessels	3%
1100	Hypoplastic Left Heart Syndrome	3%
1101	May-Thurner Syndrome	3%
1102	Genetic Diseases, Inborn	2.9%
1103	Craniofacial Dysostosis	2.9%
1104	Wolff-Parkinson-White Syndrome	2.9%
1105	Hoarseness	2.9%
1106	Alcohol Withdrawal Delirium	2.9%
1107	Prognathism	2.9%
1108	Polyradiculopathy	2.9%
1109	Post-Traumatic Headache	2.9%
1110	Tension Headache	2.9%
1111	Epilepsy, Complex Partial	2.9%
1112	Migraine Disorders	2.9%
1113	Abdominal Migraine	2.9%
1114	Status Migrainosus	2.9%
1115	Cervicogenic Headache	2.9%
1116	Eye Injuries	2.9%
1117	Paranasal Sinus Neoplasms	2.8%
1118	Orbital Myositis	2.8%
1119	Diplopia	2.8%
1120	Muscle Rigidity	2.8%
1121	Muscle Spasticity	2.8%
1122	Scotoma	2.8%
1123	Photophobia	2.8%
1124	Cogwheel Rigidity	2.8%
1125	Hemifacial Spasm	2.8%
1126	Amaurosis	2.8%
1127	Blindness	2.8%
1128	Nuchal Rigidity	2.8%
1129	Reye Syndrome	2.8%
1130	Neuroaspergillosis	2.8%
1131	Pyomyositis	2.8%
1132	Intracranial Embolism and Thrombosis	2.8%
1133	Hepatic Encephalopathy	2.8%
1134	Agnosia	2.8%
1135	Apraxias	2.8%
1136	Hallucinations	2.8%
1137	Hemianopsia	2.8%
1138	Hyperacusis	2.8%
1139	Tinnitus	2.8%
1140	Visual Agnosia	2.8%
1141	Anosognosia	2.8%
1142	Wernicke-Korsakoff Syndrome	2.8%
1143	Phonophobia	2.8%
1144	Hearing Loss	2.8%
1145	Sarcopenia	2.8%
1146	Long QT Syndrome	2.7%
1147	Platybasia	2.7%
1148	Tricuspid Atresia	2.7%
1149	Arrhythmogenic Right Ventricular Dysplasia	2.7%
1150	Anus Neoplasms	2.7%
1151	Sigmoid Neoplasms	2.7%
1152	Gonadal Dysgenesis	2.7%
1153	Bronchomalacia	2.7%
1154	Adrenogenital Syndrome	2.7%
1155	Tracheomalacia	2.7%
1156	Ovotesticular Disorders of Sex Development	2.7%
1157	Nesidioblastosis	2.7%
1158	Pseudorabies	2.6%
1159	Maxillary Sinus Neoplasms	2.6%
1160	Empty Sella Syndrome	2.6%
1161	Hyperpituitarism	2.6%
1162	Hypopituitarism	2.6%
1163	Hypophysitis	2.6%
1164	Cluster Headache	2.6%
1165	Migraine with Aura	2.6%
1166	Familial Hemiplegic Migraine	2.6%
1167	Chronic Paroxysmal Hemicrania	2.6%
1168	SUNCT Syndrome	2.6%
1169	Paroxysmal Hemicrania	2.6%
1170	Cerebral Arterial Diseases	2.6%
1171	Vertebrobasilar Insufficiency	2.6%
1172	Anterior Spinal Artery Syndrome	2.6%
1173	Basilar Artery Stenosis	2.6%
1174	Vertebral Artery Stenosis	2.6%
1175	Sleep Apnea, Obstructive	2.6%
1176	Sleep Apnea, Central	2.6%
1177	Intracranial Hemorrhage, Hypertensive	2.6%
1178	Transient Cerebral Ischemia	2.6%
1179	Amnesia	2.6%
1180	Delirium	2.6%
1181	Dissociative Amnesia	2.6%
1182	Color blindness	2.6%
1183	Global Amnesia	2.6%
1184	Narcolepsy	2.6%
1185	Trigeminal Neuralgia	2.6%
1186	Kleine-Levin Syndrome	2.6%
1187	Agraphia	2.6%
1188	Anomia	2.6%
1189	Cluttering	2.6%
1190	Language Development Disorders	2.6%
1191	Speech Disorders	2.6%
1192	Syncope	2.6%
1193	Stupor	2.6%
1194	Dysgraphia	2.6%
1195	Presyncope	2.6%
1196	Dyslalia	2.6%
1197	Neurosyphilis	2.6%
1198	Wernicke Encephalopathy	2.4%
1199	AIDS Dementia Complex	2.4%
1200	Eye Burns	2.4%
1201	Malaria, Cerebral	2.4%
1202	Phantom pain	2.4%
1203	Phantom Limb Pain	2.4%
1204	Carotid Stenosis	2.4%
1205	Intracranial Aneurysm	2.4%
1206	Lyme Neuroborreliosis	2.4%
1207	Neurocysticercosis	2.4%
1208	Amaurosis Fugax	2.4%
1209	Blindness, Cortical	2.4%
1210	Dyscalculia	2.4%
1211	Hyperprolactinemia	2.4%
1212	Intracranial Arteriosclerosis	2.4%
1213	Cerebral Atherosclerosis	2.4%
1214	Subarachnoid Hemorrhage	2.4%
1215	Cerebral Arteriosclerosis	2.4%
1216	Cerebral Hemorrhage	2.4%
1217	Cerebral Thrombosis	2.4%
1218	Intracranial Embolism	2.4%
1219	Intracranial Thrombosis	2.4%
1220	Deafness	2.4%
1221	Hearing Loss, Sudden	2.4%
1222	Gerstmann Syndrome	2.4%
1223	Hearing Loss, Bilateral	2.4%
1224	Hearing Loss, High-Frequency	2.4%
1225	Hearing Loss, Mixed Conductive-Sensorineural	2.4%
1226	Prosopagnosia	2.4%
1227	Apraxia, Ideomotor	2.4%
1228	Charles Bonnet Syndrome	2.4%
1229	Hearing Loss, Unilateral	2.4%
1230	Complete Hearing Loss	2.4%
1231	Alien Hand Syndrome	2.4%
1232	Deaf Mutism	2.4%
1233	Subclavian Steal Syndrome	2.4%
1234	Pick Disease of the Brain	2.4%
1235	Cataplexy	2.4%
1236	Aphasia	2.4%
1237	Articulation Disorders	2.4%
1238	Echolalia	2.4%
1239	Stuttering	2.4%
1240	Dysphasia	2.4%
1241	Dysarthria	2.2%
1242	Aortopulmonary Septal Defect	2.2%
1243	Double Outlet Right Ventricle	2.2%
1244	Endocardial Cushion Defects	2.2%
1245	Myocardial bridging	2.2%
1246	Aorticopulmonary Septal Defect	2.2%
1247	Dermatomyositis	2.2%
1248	Corneal Scar	2.2%
1249	Retrograde amnesia	2.2%
1250	Amnesia, Anterograde	2.2%
1251	Carotid Artery Thrombosis	2.2%
1252	Mutism	2.2%
1253	Selective Mutism	2.2%
1254	Acromegaly	2.2%
1255	Cerebral Amyloid Angiopathy	2.2%
1256	Sinus Thrombosis, Intracranial	2.2%
1257	Hyaline Membrane Disease	2.1%
1258	Mandibulofacial Dysostosis	2.1%
1259	Alexia, Pure	2.1%
1260	Romano-Ward Syndrome	2.1%
1261	Cavernous Sinus Thrombosis	2%
1262	Sagittal Sinus Thrombosis	2%
1263	Corneal Perforation	2%
1264	Truncus Arteriosus, Persistent	1.9%
1265	Goldenhar Syndrome	1.9%
1266	Arteriovenous fistula	1.8%
1267	Talipes	1.7%
1268	Congenital clubfoot	1.6%
1269	Vertical Talus	1.6%

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