MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Abnormalities, Radiation-Induced

(UMLS:C0000773)

Definition:: Congenital changes in the morphology of organs produced by exposure to ionizing or non-ionizing radiation.
UMLS ID:: C0000773
MeSH ID:: D000016

Classification 1:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.080

Classification 2:

Name:

Wounds and Injuries
MeSH Tree Number(s):: C26.733.031

Classification 3:

Name:

Physical Phenomena
MeSH Tree Number(s):: G01.750.748.500.031

Classification 4:

Name:

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MeSH Tree Number(s):: N06.850.460.350.850.500.031|N06.850.810.300.360.031

Synonym(s)

Abnormalities, Radiation-Induced

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Cadmium Chloride		25853276	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Radiation Injuries, Experimental	40%
2	Osteoradionecrosis	25.8%
3	Neoplasms, Radiation-Induced	23.2%
4	Cardiotoxicity	20.4%
5	Leukemia, Radiation-Induced	20.2%
6	Radiation Pneumonitis	20.1%
7	Radiation Fibrosis	20.1%
8	Holoprosencephaly	19.9%
9	Beckwith-Wiedemann Syndrome	17.5%
10	Wolf-Hirschhorn Syndrome	17.5%
11	Rubinstein-Taybi Syndrome	15.7%
12	Smith-Magenis syndrome	15.7%
13	Aicardi's syndrome	15.6%
14	Cri-du-Chat Syndrome	15.5%
15	Down Syndrome	15.5%
16	Trisomy 21	15.5%
17	Kartagener Syndrome	14.3%
18	Ectodermal Dysplasia	14%
19	Aplasia Cutis Congenita	14%
20	Prader-Willi Syndrome	13.9%
21	Anencephaly	13.7%
22	Abnormalities, Drug-Induced	13.5%
23	Situs Inversus	13.5%
24	Water Pollution	12.9%
25	Maxillofacial Abnormalities	12.3%
26	Dural Arteriovenous Fistula	12.3%
27	Dextrocardia	12.2%
28	Eye Abnormalities	11.9%
29	Cardiovascular Abnormalities	11.9%
30	Acrocephalosyndactylia	11.6%
31	Skin Abnormalities	11.6%
32	Lymphatic Abnormalities	11.6%
33	Congenital Microtia	11.6%
34	Marfan Syndrome	11.5%
35	Congenital diaphragmatic hernia	11.5%
36	Drowning	11.2%
37	CHARGE Syndrome	10.9%
38	Turner Syndrome	10.8%
39	Alstrom Syndrome	10.8%
40	Urogenital Abnormalities	10.4%
41	Microcephaly	10.4%
42	Macrocephaly	10.4%
43	Classical Lissencephalies and Subcortical Band Heterotopias	10.2%
44	Scimitar Syndrome	10.1%
45	Prune Belly Syndrome	10%
46	Twins, Conjoined	10%
47	Waardenburg Syndrome	10%
48	Frostbite	9.9%
49	Craniosynostosis	9.9%
50	Syndactyly	9.9%
51	Brachycephaly	9.9%
52	Fragile X Syndrome	9.8%
53	Porencephaly	9.8%
54	Nail-Patella Syndrome	9.8%
55	Xeroderma	9.7%
56	Mobius Syndrome	9.7%
57	Cleft Palate	9.7%
58	Noonan Syndrome	9.1%
59	Cockayne Syndrome	9.1%
60	Ichthyosis, X-Linked	8.9%
61	Polycystic Kidney Diseases	8.8%
62	Williams Syndrome	8.8%
63	Poland Syndrome	8.8%
64	Anophthalmos	8.6%
65	Anus, Imperforate	8.6%
66	Hydranencephaly	8.6%
67	Microphthalmos	8.6%
68	Neural Tube Defects	8.6%
69	Tethered Cord Syndrome	8.6%
70	Iniencephaly	8.6%
71	Craniorachischisis	8.6%
72	Limb Deformities, Congenital	8.6%
73	Exencephaly	8.6%
74	Septo-Optic Dysplasia	8.6%
75	Craniofacial Abnormalities	8.6%
76	Cortical Dysplasia	8.6%
77	Malformations of Cortical Development	8.6%
78	Anorectal Malformations	8.6%
79	Jaw Abnormalities	8.6%
80	Bloom Syndrome	8.6%
81	Klinefelter Syndrome	8.6%
82	Hip Fractures	8.4%
83	Smith-Lemli-Opitz Syndrome	8.4%
84	Retinal Dysplasia	8.2%
85	Aniridia	8.1%
86	Primary Ciliary Dyskinesia	8.1%
87	Epidermolysis Bullosa	8%
88	Micrognathism	7.8%
89	Pierre Robin Syndrome	7.8%
90	Near Drowning	7.8%
91	Crush syndrome	7.8%
92	Femoral Fractures	7.8%
93	Tibial Fractures	7.8%
94	Blepharophimosis	7.6%
95	Laryngostenosis	7.6%
96	Mouth Abnormalities	7.6%
97	Esophageal Atresia	7.6%
98	Intestinal Atresia	7.6%
99	Horseshoe Kidney	7.6%
100	Pectus excavatum	7.6%
101	Klippel-Feil Syndrome	7.5%
102	Gastroschisis	7.5%
103	Synostosis	7.5%
104	Acrodermatitis	7.5%
105	Lymphangiectasis, Intestinal	7.5%
106	Gianotti-Crosti Syndrome	7.5%
107	Sjogren-Larsson Syndrome	7.4%
108	Polycystic Kidney, Autosomal Dominant	7.3%
109	Retrognathia	7.2%
110	Amelia	7.1%
111	Arachnodactyly	7.1%
112	Ectopia Cordis	7.1%
113	Ectromelia	7.1%
114	Hemimelia	7.1%
115	Meningomyelocele	7.1%
116	Phocomelia	7.1%
117	Sirenomelia	7.1%
118	Spina Bifida	7.1%
119	Polydactyly	7.1%
120	Brachydactyly	7.1%
121	Plagiocephaly	7.1%
122	Lower Extremity Deformities, Congenital	7.1%
123	Upper Extremity Deformities, Congenital	7.1%
124	Single umbilical artery	7.1%
125	Hyperkeratosis, Epidermolytic	7%
126	Athletic Injuries	6.9%
127	Hand Injuries	6.9%
128	Soft Tissue Injuries	6.9%
129	Sprain	6.9%
130	Sprains and Strains	6.9%
131	Tendon Injuries	6.9%
132	Laceration	6.9%
133	Wounds, Penetrating	6.9%
134	Heat Cramps	6.9%
135	Genetic Diseases, Inborn	6.9%
136	Rupture	6.9%
137	Arthrogryposis	6.8%
138	Choanal Atresia	6.8%
139	Tracheobronchomegaly	6.8%
140	Laryngocele	6.8%
141	Hip Dislocation	6.8%
142	Shoulder Dislocation	6.8%
143	Splenic Rupture	6.8%
144	Hip Dysplasia	6.8%
145	Choledochal Cyst	6.8%
146	Hermaphroditism	6.8%
147	Disorders of Sex Development	6.8%
148	Hyperandrogenism	6.7%
149	Chilblains	6.7%
150	Paralysis, Obstetric	6.7%
151	Spinal Fractures	6.7%
152	Cryptorchidism	6.7%
153	Hypospadias	6.7%
154	Central Nervous System Cysts	6.7%
155	Pseudoxanthoma Elasticum	6.7%
156	Dandy-Walker Syndrome	6.7%
157	Prognathism	6.6%
158	POEMS Syndrome	6.6%
159	Charcot-Marie-Tooth Disease	6.6%
160	Antley-Bixler Syndrome Phenotype	6.6%
161	Kallmann Syndrome	6.5%
162	Dermal Sinus	6.3%
163	Spina Bifida Cystica	6.3%
164	Spina Bifida Occulta	6.3%
165	Lissencephaly	6.3%
166	Polymicrogyria	6.3%
167	Pachygyria	6.3%
168	Schizencephaly	6.3%
169	Periventricular Nodular Heterotopia	6.3%
170	Aortic coarctation	6.2%
171	Cor Triatriatum	6.2%
172	Coronary Vessel Anomalies	6.2%
173	Dental Enamel Hypoplasia	6.2%
174	Patent ductus arteriosus	6.2%
175	Ebstein Anomaly	6.2%
176	Heart Septal Defects	6.2%
177	Hypodontia	6.2%
178	Macrostomia	6.2%
179	Meningocele	6.2%
180	Microstomia	6.2%
181	Tetralogy of Fallot	6.2%
182	Transposition of Great Vessels	6.2%
183	Hypoplastic Left Heart Syndrome	6.2%
184	May-Thurner Syndrome	6.2%
185	Encephalocele	6.2%
186	Craniofacial Dysostosis	6.2%
187	Xeroderma Pigmentosum	6.2%
188	Wolff-Parkinson-White Syndrome	6.2%
189	Tuberous Sclerosis	6.1%
190	Zellweger Syndrome	6.1%
191	Laryngomalacia	6.1%
192	Refsum Disease	6.1%
193	Cystic Fibrosis	6.1%
194	Pectus carinatum	6.1%
195	Trauma, Nervous System	6.1%
196	Bladder Exstrophy	6%
197	Epispadias	6%
198	Multicystic Dysplastic Kidney	6%
199	Bites and Stings	5.9%
200	Extravasation of Diagnostic and Therapeutic Materials	5.9%
201	Fetal Diseases	5.9%
202	Vascular System Injuries	5.9%
203	Tympanic Membrane Perforation	5.9%
204	Tooth Injuries	5.9%
205	Asphyxia	5.9%
206	Esophageal Perforation	5.9%
207	Shock, Traumatic	5.9%
208	Self Mutilation	5.8%
209	Iliotibial Band Syndrome	5.7%
210	Basal Cell Nevus Syndrome	5.7%
211	Aortopulmonary Septal Defect	5.5%
212	Double Outlet Right Ventricle	5.5%
213	Endocardial Cushion Defects	5.5%
214	Myocardial bridging	5.5%
215	Aorticopulmonary Septal Defect	5.5%
216	Long QT Syndrome	5.5%
217	Platybasia	5.5%
218	Tricuspid Atresia	5.5%
219	Arrhythmogenic Right Ventricular Dysplasia	5.5%
220	Gonadal Dysgenesis	5.5%
221	Bronchomalacia	5.5%
222	Adrenogenital Syndrome	5.5%
223	Tracheomalacia	5.5%
224	Ovotesticular Disorders of Sex Development	5.5%
225	Meconium Aspiration Syndrome	5.4%
226	Truncus Arteriosus, Persistent	5.2%
227	Goldenhar Syndrome	5.2%
228	Eye Burns	5.2%
229	Spinal Cord Injuries	5.2%
230	Splenosis	5%
231	Mandibulofacial Dysostosis	4.9%
232	Romano-Ward Syndrome	4.9%
233	Mucopolysaccharidosis II	4.7%
234	Albinism	4.7%
235	Talipes	4.7%
236	Brain Concussion	4.6%
237	Abdominal Cramps	4.5%
238	Amniotic Band Syndrome	4.5%
239	Asphyxia Neonatorum	4.5%
240	Human Bite	4.5%
241	Contusions	4.5%
242	Decompression Sickness	4.5%
243	Finger Injuries	4.5%
244	Flail Chest	4.5%
245	Fractures, Closed	4.5%
246	Pathological fracture	4.5%
247	Heart Injuries	4.5%
248	Heat Exhaustion	4.5%
249	Heat Stroke	4.5%
250	Infant, Premature, Diseases	4.5%
251	Knee Injuries	4.5%
252	Foot Injuries	4.5%
253	Decapitation	4.5%
254	Ankle Fracture	4.5%
255	Infantile Colic	4.5%
256	Avulsion fracture	4.5%
257	Compression fracture	4.5%
258	Osteoporotic Fractures	4.5%
259	Congenital clubfoot	4.5%
260	Vertical Talus	4.5%
261	Anemia, Sickle Cell	4.4%
262	Thalassemia	4.4%
263	Muscular Dystrophy, Duchenne	4.4%
264	Menkes Kinky Hair Syndrome	4.3%
265	Environmental Exposure	4.2%
266	Rett Syndrome	4.1%
267	Arteriovenous fistula	4%
268	Neoplastic Syndromes, Hereditary	4%
269	Multimorbidity	3.9%
270	Craniocerebral Trauma	3.9%
271	Tendinitis	3.9%
272	Lung Injury	3.9%
273	Tendinopathy	3.9%
274	Anemia, Neonatal	3.8%
275	Foreign-Body Reaction	3.8%
276	Insect Bites and Stings	3.8%
277	Multiple Epiphyseal Dysplasia	3.8%
278	Osteochondrodysplasias	3.8%
279	Pelger-Huet Anomaly	3.8%
280	Persistent Fetal Circulation Syndrome	3.8%
281	Sunburn	3.8%
282	Tooth Avulsion	3.8%
283	Werner Syndrome	3.8%
284	Conus Medullaris Syndrome	3.8%
285	Myasthenic Syndromes, Congenital	3.8%
286	Brain Contusion	3.8%
287	Umbilical hernia	3.8%
288	Adrenoleukodystrophy	3.8%
289	Sickle Cell Trait	3.6%
290	Wiskott-Aldrich Syndrome	3.6%
291	Fabry Disease	3.5%
292	Denys-Drash Syndrome	3.5%
293	Neuronal Ceroid-Lipofuscinoses	3.5%
294	Dwarfism	3.4%
295	Neonatal Abstinence Syndrome	3.4%
296	Peripheral Nerve Injuries	3.4%
297	Medial Tibial Stress Syndrome	3.4%
298	Fetal Growth Retardation	3.4%
299	Glycogen storage disease type II	3.4%
300	Muscular Dystrophy	3.3%
301	Osteogenesis Imperfecta	3.3%
302	Uterine Rupture	3.3%
303	Fetal Hypoxia	3.3%
304	Central Cord Syndrome	3.3%
305	Congenital nystagmus	3.3%
306	Fetal Alcohol Spectrum Disorders	3.3%
307	Familial Mediterranean Fever	3.3%
308	Pseudarthrosis	3.3%
309	Smoke Inhalation Injury	3.3%
310	Toxoplasmosis, Congenital	3.3%
311	Syphilis, Congenital	3.3%
312	Myotonic Dystrophy	3.3%
313	Hepatolenticular Degeneration	3.3%
314	Acute Chest Syndrome	3%
315	Autoimmune Lymphoproliferative Syndrome	3%
316	Amyloid Neuropathies, Familial	3%
317	Congenital Hyperinsulinism	3%
318	Chorioamnionitis	3%
319	Galactosemias	3%
320	Urea Cycle Disorders, Inborn	3%
321	Tyrosinemias	3%
322	Aortic Rupture	2.9%
323	Angioedemas, Hereditary	2.9%
324	Mucopolysaccharidosis III	2.9%
325	Gaucher Disease	2.9%
326	Hydrops Fetalis	2.9%
327	Retinopathy of Prematurity	2.9%
328	Amino Acid Metabolism, Inborn Errors	2.9%
329	Carbohydrate Metabolism, Inborn Errors	2.9%
330	Facial Injuries	2.9%
331	Granuloma, Foreign-Body	2.9%
332	Metal Metabolism, Inborn Errors	2.9%
333	Progeria	2.9%
334	Lysosomal Storage Diseases	2.9%
335	Enthesopathy	2.9%
336	Cytochrome-c Oxidase Deficiency	2.9%
337	Peroxisomal Disorders	2.9%
338	Bronchopulmonary Dysplasia	2.8%
339	Uterine Perforation	2.8%
340	Tay-Sachs Disease	2.8%
341	Optic Atrophy, Hereditary, Leber	2.7%
342	Hyperphosphaturia	2.7%
343	Brain Hemorrhage, Traumatic	2.7%
344	Niemann-Pick Disease, Type C	2.6%
345	Canavan Disease	2.6%
346	Alexander Disease	2.6%
347	Homocystinuria	2.6%
348	Leigh Disease	2.6%
349	Patient Isolation	2.6%
350	Respiratory Distress Syndrome, Newborn	2.5%
351	Radiation injury	2.5%
352	Cutis Laxa	2.5%
353	Retinitis Pigmentosa	2.5%
354	Pigmentary retinopathy	2.5%
355	Porokeratosis	2.5%
356	Brain Injuries	2.5%
357	Keratoderma, Palmoplantar	2.5%
358	Chronic granulomatous disease	2.5%
359	Coma, Post-Head Injury	2.5%
360	Carpal Tunnel Syndrome	2.5%
361	Welander Distal Myopathy	2.5%
362	Carbamoyl-Phosphate Synthase I Deficiency Disease	2.4%
363	Ophthalmia Neonatorum	2.4%
364	Alkaptonuria	2.4%
365	Glycogen Storage Disease	2.4%
366	Hypophosphatasia	2.4%
367	Propionic acidemia	2.4%
368	Dihydropyrimidine Dehydrogenase Deficiency	2.4%
369	Cystinosis	2.4%
370	Duane Retraction Syndrome	2.3%
371	Porphyrias, Hepatic	2.2%
372	Ataxia Telangiectasia	2.2%
373	Peutz-Jeghers Syndrome	2.2%
374	Myotonia Congenita	2.2%
375	Thrombasthenia	2.2%
376	Antithrombin III Deficiency	2.2%
377	Protein C Deficiency	2.2%
378	Brain Diseases, Metabolic, Inborn	2.2%
379	Afibrinogenemia	2.2%
380	Dystonia Musculorum Deformans	2.2%
381	Factor VII Deficiency	2.2%
382	Factor X Deficiency	2.2%
383	Factor XII Deficiency	2.2%
384	Hemophilia A	2.2%
385	Leukomalacia, Periventricular	2.2%
386	Activated Protein C Resistance	2.2%
387	Factor II deficiency	2.2%
388	Factor VIII Deficiency	2.2%
389	Factor V deficiency	2.2%
390	Factor XI Deficiency	2.2%
391	Hypoprothrombinemias	2.2%
392	Fanconi Anemia	2.2%
393	Nesidioblastosis	2.2%
394	Lafora Disease	2.2%
395	Unverricht-Lundborg Syndrome	2.2%
396	Anemia, Diamond-Blackfan	2.2%
397	Eye Injuries	2.1%
398	Glycogen Storage Disease Type I	2.1%
399	Glycogen Storage Disease Type V	2.1%
400	Hyaline Membrane Disease	2.1%
401	Hypolipoproteinemias	2.1%
402	Papillon-Lefevre Disease	2.1%
403	Brain Injuries, Diffuse	2.1%
404	Traumatic Brain Injury	2.1%
405	Hyperlipidemia, Familial Combined	2.1%
406	Hyperlipoproteinemia Type III	2%
407	Cubital Tunnel Syndrome	2%
408	Multiple Endocrine Neoplasia	2%
409	Congenital Hypothyroidism	2%
410	Dermatitis, Atopic	2%
411	Vertebral Artery Dissection	2%
412	Body mass index	1.9%
413	Familial Periodic Paralysis	1.9%
414	Pneumocephalus	1.8%
415	Hypoalphalipoproteinemias	1.8%
416	Diffuse Axonal Injury	1.8%
417	Olfactory Nerve Injuries	1.8%
418	Cerebrospinal Fluid Otorrhea	1.8%
419	Cerebrospinal Fluid Rhinorrhea	1.8%
420	Lactose Intolerance	1.8%
421	Variegate Porphyria	1.8%
422	Acute intermittent porphyria	1.8%
423	Porphyria Cutanea Tarda	1.8%
424	Hyperhomocysteinemia	1.8%
425	Epilepsy, Post-Traumatic	1.8%
426	Kernicterus	1.8%
427	Renal Aminoacidurias	1.8%
428	Fanconi Syndrome	1.8%
429	Pseudohypoaldosteronism	1.8%
430	Liddle Syndrome	1.8%
431	Behcet Syndrome	1.8%
432	Hyperlipoproteinemia Type IV	1.8%
433	Hyperlipoproteinemia Type V	1.8%
434	Carotid Artery Injuries	1.8%
435	Familial Hypophosphatemic Rickets	1.7%
436	Corneal Scar	1.7%
437	Gout	1.7%
438	Multiple Endocrine Neoplasia Type 1	1.7%
439	Pseudohypoparathyroidism	1.7%
440	Facial Nerve Injuries	1.7%
441	Huntington Disease	1.6%
442	Hypokalemic periodic paralysis	1.6%
443	Friedreich Ataxia	1.6%
444	Renal tubular acidosis	1.6%
445	Cystinuria	1.6%
446	Corneal Perforation	1.6%
447	Nephroblastoma	1.5%
448	Abnormalities, Radiation-Induced	1.5%
449	Hematoma, Subdural	1.5%
450	Hematoma, Epidural, Cranial	1.5%
451	Arthritis, Gouty	1.5%
452	Adenomatous Polyposis Coli	1.4%
453	Glycosuria, Renal	1.4%
454	Subarachnoid Hemorrhage, Traumatic	1.4%
455	Carotid Artery, Internal, Dissection	1.4%
456	Hematoma, Subdural, Intracranial	1.3%
457	Hematoma, Subdural, Chronic	1.3%
458	Hematoma, Subdural, Acute	1.3%
459	MELAS Syndrome	1.2%

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