MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hypoglycemia

(UMLS:C0020615)

Definition:: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
UMLS ID:: C0020615
MeSH ID:: D007003

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.452.394.984

Synonym(s)

Hypoglycemia

Blood Glucose, Low

Glucose, Low Blood

HYPOGLYCEMIA

Hypoglycaemia

Hypoglycaemia, NOS

Hypoglycaemia, unspecified

Hypoglycaemic disorder

Hypoglycaemic syndrome, NOS

Associated Drug(s)

	Name	Reference(s)	Data Source
1	1,3-butylene glycol	6497141	CTD
2	2-tetradecylglycidic acid	10424880	CTD
3	3,4,5,3',4'-pentachlorobiphenyl	29474705	CTD
4	5-thio-D-glucose	3084764	CTD
5	Acetaminophen	View details 1735538 6637917 6779949 8214766 10447915 10801061	CTD
6	Acetohexamide	5935425	CTD
7	Albuterol	15232249	CTD
8	Aspirin	5488183 11431304	CTD
9	Azoxymethane	20198438	CTD
10	Buthionine Sulfoximine	1735538	CTD
11	Chloroquine	8162653	CTD
12	Chlorpropamide	View details 879949 1201169 2043180 4848193 5560028 7057563 7396601	CTD
13	Chromium	16445588	CTD
14	Cimetidine	2414028	CTD
15	Clonidine	11487765	CTD
16	Cocaine	11435200 16033719	CTD
17	Deoxyglucose	2280799	CTD
18	Dexamethasone	8774068	CTD
19	Diazoxide	View details 2040926 3970573 4299224 4387262 5544160	CTD
20	Dichlorvos	4017989	CTD
21	Diphenhydramine	2414028	CTD
22	Disopyramide	6413187	CTD
23	Enalapril	7951836	CTD
24	Glipizide	7648808	CTD
25	Glucose	View details 6421558 8422773 18545258 19427052	CTD
26	Glyburide	View details 3138822 5006096 6421558 10918110 12445037 12701389 15787664 17259518 19421967	CTD
27	Labetalol	8198664	CTD
28	Lansoprazole	12507665	CTD
29	Leucovorin	18173932	CTD
30	Lithium Carbonate	671171 6461296	CTD
31	Lithium	12114921 15830831	CTD
32	Methimazole	29990518	CTD
33	Methotrexate	18173932	CTD
34	Mirex	3508472	CTD
35	Naproxen	18173932	CTD
36	Nateglinide	11074662	CTD
37	Niacin	6497141 17418450	CTD
38	Octreotide	8422773	CTD
39	Ofloxacin	17026994 18644072	CTD
40	Pentamidine	View details 1424505 1519856 2566818 3259989 3260759 3485027 3487333 3490958	CTD
41	Phenformin	879949 10052646	CTD
42	Phlorhizin	6497141	CTD
43	Prednisone	19902248	CTD
44	Propranolol	909024 3019152 4710445	CTD
45	Ribose	30101366	CTD
46	Ritodrine	6638123	CTD
47	Saccharin	7448750	CTD
48	Streptozocin	22940631	CTD
49	Tolbutamide	879949 10052646 16087376	CTD
50	Trimethoprim, Sulfamethoxazole Drug Combination	14714756	CTD
51	Valproic Acid	8215567	CTD
52	Varenicline	18346160	CTD
53	Vitamin E	17429802	CTD
54	Warfarin	27488359	CTD
55	aluminum phosphide	9949483	CTD
56	beryllium nitrate	17429802	CTD
57	chloroacetic acid	15720133 16898262	CTD
58	hydroxyhexamide	11693275	CTD
59	meglitinide	19421967	CTD
60	pantogab	17379144	CTD
61	perhexiline maleate	680419 6246624	CTD
62	piperine	17429802	CTD
63	selenomethylselenocysteine	19010315	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hyperglycemia	46.7%
2	Hyperinsulinism	46.7%
3	Diabetes Mellitus	33.3%
4	Acid-Base Imbalance	31%
5	Calcium Metabolism Disorders	31%
6	Iron Metabolism Disorders	31%
7	Phosphorus Metabolism Disorders	31%
8	Water-Electrolyte Imbalance	31%
9	Lipid Metabolism Disorders	31%
10	Mitochondrial Diseases	31%
11	Wasting Syndrome	27.9%
12	Hypercalcemia	26.7%
13	Hypocalcemia	26.7%
14	Milk-Alkali Syndrome	26.7%
15	Diabetic Ketoacidosis	23.3%
16	Glycosuria	23.1%
17	Insulin Resistance	22.8%
18	Osteopenia	20.9%
19	Brain Diseases, Metabolic	20.5%
20	Acidosis	20%
21	Alkalosis	20%
22	Amyloidosis	20%
23	Calcinosis	20%
24	Hyperkalemia	20%
25	Hypernatremia	20%
26	Hypokalemia	20%
27	Hyponatremia	20%
28	Lipodystrophy	20%
29	Xanthomatosis	20%
30	Hypophosphatemia	20%
31	Metabolic acidosis	20%
32	Dyslipidemias	20%
33	Iron Overload	20%
34	Xanthoma	20%
35	Nutrition Disorders	18.5%
36	Pseudohypoparathyroidism	18.1%
37	Gestational Diabetes	17.9%
38	Latent Autoimmune Diabetes in Adults	17.9%
39	Diabetes Mellitus, Experimental	17.6%
40	Rickets	17.3%
41	Brain Diseases, Metabolic, Inborn	15.9%
42	Leigh Disease	15.2%
43	Hyperhomocysteinemia	15.1%
44	Acidosis, Lactic	14.8%
45	Calciphylaxis	14.8%
46	Hemosiderosis	14.8%
47	Ketosis	14.8%
48	Ketonuria	14.8%
49	Ketoacidosis	14.8%
50	Ketonemia	14.8%
51	Vascular calcification	14.8%
52	Hypolipoproteinemias	14.6%
53	Hyperlipoproteinemia Type IV	14.5%
54	Hyperlipoproteinemia Type V	14.5%
55	Congenital Hyperinsulinism	14.2%
56	Carbamoyl-Phosphate Synthase I Deficiency Disease	13.8%
57	Lactose Intolerance	13.7%
58	Dehydration	13.6%
59	Lipomatosis	13.6%
60	Water Intoxication	13.6%
61	Werner Syndrome	13.6%
62	Hyperlipidemia, Familial Combined	13.4%
63	Achlorhydria	13.3%
64	Amino Acid Metabolism, Inborn Errors	13.3%
65	Bloom Syndrome	13.3%
66	Carbohydrate Metabolism, Inborn Errors	13.3%
67	Metal Metabolism, Inborn Errors	13.3%
68	Osteoporosis	13.3%
69	Progeria	13.3%
70	Lysosomal Storage Diseases	13.3%
71	Bone Demineralization, Pathologic	13.3%
72	Cytochrome-c Oxidase Deficiency	13.3%
73	Peroxisomal Disorders	13.3%
74	Post-Traumatic Osteoporosis	13.3%
75	Celiac Disease	13.2%
76	Sprue, Tropical	13.2%
77	Steatorrhea	13.2%
78	Sprue	13.2%
79	Osteomalacia	13%
80	Hyperlipoproteinemia Type III	12.7%
81	Smith-Lemli-Opitz Syndrome	12.6%
82	Galactosemias	12.5%
83	Urea Cycle Disorders, Inborn	12.5%
84	Tyrosinemias	12.5%
85	Hypercholesterolemia	12.2%
86	Hyperlipoproteinemias	12.2%
87	Hypertriglyceridemia	12.2%
88	Glycosuria, Renal	12.1%
89	Hypoalphalipoproteinemias	12%
90	Familial Hypophosphatemic Rickets	11.5%
91	Mitochondrial Encephalomyopathies	11.5%
92	Nesidioblastosis	11.4%
93	Gaucher Disease	10.9%
94	Hyperphosphaturia	10.9%
95	Glycogen storage disease type II	10.6%
96	Homocystinuria	10.4%
97	Child Nutrition Disorders	10.3%
98	Hypervitaminosis A	10.3%
99	Infant Nutrition Disorders	10.3%
100	Malnutrition	10.3%
101	Mitochondrial Myopathies	10.2%
102	Myelinolysis, Central Pontine	10.1%
103	Reye Syndrome	9.9%
104	Acidosis, Respiratory	9.9%
105	Adiposis Dolorosa	9.9%
106	Alkalosis, Respiratory	9.9%
107	Hepatic Encephalopathy	9.8%
108	Tay-Sachs Disease	9.8%
109	Alkaptonuria	9.8%
110	Glycogen Storage Disease	9.8%
111	Hypophosphatasia	9.8%
112	Osteoporosis, Postmenopausal	9.8%
113	Propionic acidemia	9.8%
114	Dihydropyrimidine Dehydrogenase Deficiency	9.8%
115	Cystinosis	9.8%
116	Amyloid Neuropathies, Familial	9.8%
117	Renal tubular acidosis	9.7%
118	Niemann-Pick Disease, Type C	9.3%
119	Neuronal Ceroid-Lipofuscinoses	9%
120	HIV Wasting Syndrome	8.8%
121	Fabry Disease	8.5%
122	HIV-Associated Lipodystrophy Syndrome	8.4%
123	MELAS Syndrome	8.2%
124	Renal Osteodystrophy	8.2%
125	Renal rickets	8.2%
126	Porphyrias, Hepatic	8.1%
127	Glycogen Storage Disease Type I	8.1%
128	Glycogen Storage Disease Type V	8.1%
129	Zellweger Syndrome	8%
130	Mucopolysaccharidosis III	8%
131	Adrenoleukodystrophy	8%
132	Necrobiosis Lipoidica Diabeticorum	7.9%
133	Menkes Kinky Hair Syndrome	7.9%
134	Fanconi Anemia	7.8%
135	Wernicke Encephalopathy	7.7%
136	Hepatolenticular Degeneration	7.4%
137	Nephrocalcinosis	7.4%
138	Tetany	7.4%
139	Refsum Disease	7.3%
140	Cerebral Amyloid Angiopathy	7.2%
141	Deficiency Diseases	6.7%
142	Starvation	6.7%
143	Refeeding Syndrome	6.7%
144	Friedreich Ataxia	6.5%
145	Familial Periodic Paralysis	6%
146	Primary amyloidosis	6%
147	Variegate Porphyria	5.9%
148	Acute intermittent porphyria	5.9%
149	Porphyria Cutanea Tarda	5.9%
150	Renal Aminoacidurias	5.8%
151	Fanconi Syndrome	5.8%
152	Pseudohypoaldosteronism	5.8%
153	Liddle Syndrome	5.8%
154	Kernicterus	5.7%
155	Kearns-Sayre syndrome	5.7%
156	Cockayne Syndrome	5.7%
157	Canavan Disease	5.4%
158	Alexander Disease	5.4%
159	Sjogren-Larsson Syndrome	5.4%
160	Mucopolysaccharidosis II	5.3%
161	Ataxia Telangiectasia	5.1%
162	Gout	5%
163	Amyotrophic Lateral Sclerosis	5%
164	Kwashiorkor	4.9%
165	Magnesium Deficiency	4.9%
166	Potassium Deficiency	4.9%
167	Protein Deficiency	4.9%
168	Avitaminosis	4.9%
169	Optic Atrophy, Hereditary, Leber	4.9%
170	Antley-Bixler Syndrome Phenotype	4.9%
171	Hypokalemic periodic paralysis	4.9%
172	Frontotemporal dementia	4.8%
173	Cystinuria	4.8%
174	Xeroderma Pigmentosum	4.5%
175	CREST Syndrome	4.2%
176	Ascorbic Acid Deficiency	4.1%
177	Vitamin A Deficiency	4.1%
178	Vitamin D Deficiency	4.1%
179	Vitamin E Deficiency	4.1%
180	Marasmus	4.1%
181	Arthritis, Gouty	4.1%
182	Albinism	3.7%
183	Folic Acid Deficiency	3.6%
184	Pellagra	3.6%
185	Thiamine Deficiency	3.6%
186	Vitamin B 12 Deficiency	3.6%
187	Vitamin B 6 Deficiency	3.6%
188	Pyridoxine Deficiency	3.6%
189	Beriberi	3.4%
190	Ichthyosis, X-Linked	3%
191	Obesity	2.6%
192	Obesity, Abdominal	2.4%
193	Anemia, Pernicious	2.3%
194	Vitamin K Deficiency	2.1%
195	Pediatric Obesity	1.9%
196	Scurvy	1.8%
197	Prader-Willi Syndrome	1.6%
198	Subacute Combined Degeneration	1.2%

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