MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Polycystic Kidney, Autosomal Dominant

(UMLS:C0085413)

Definition:: Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.
UMLS ID:: C0085413
MeSH ID:: D016891

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.419.403.875.500

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.419.403.875.500

Classification 3:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.077.717.500|C16.320.184.625.500

Synonym(s)

Polycystic Kidney, Autosomal Dominant

ADPKD - Autosomal dominant polycystic kidney disease

ADPKD - autosomal dominant polycystic kidney disease

Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant adult polycystic kidney disease

Autosomal dominant polycystic kidney disease

Polycystic kidney disease, adult type

Polycystic kidney, adult type

Polycystic kidney, autosomal dominant

10.

Polycystic kidneys - adult type

11.

adpkd

12.

adult disease kidney polycystic

13.

adult polycystic kidney disease

14.

autosomal dominant polycystic kidney disease

15.

cyst; kidney, multiple, adult type

16.

polycystic; degeneration, kidney, adult type

17.

polycystic; kidney, adult type

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Sirolimus		19651290	CTD
2	Tolvaptan		26507107	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Multicystic Dysplastic Kidney	25%
2	Beckwith-Wiedemann Syndrome	22.3%
3	Wolf-Hirschhorn Syndrome	22.3%
4	Anuria	21.2%
5	Nephrolithiasis	21.2%
6	CHARGE Syndrome	20.6%
7	Urogenital Abnormalities	20.1%
8	Smith-Magenis syndrome	19.7%
9	Cri-du-Chat Syndrome	19.5%
10	Down Syndrome	19.5%
11	Trisomy 21	19.5%
12	Hydronephrosis	19.5%
13	Hyperoxaluria	19.5%
14	Kidney Cortex Necrosis	19.5%
15	Kidney Papillary Necrosis	19.5%
16	Nephritis	19.5%
17	Nephrosclerosis	19.5%
18	Nephrosis	19.5%
19	Perinephritis	19.5%
20	Kidney Failure	19.5%
21	Uremia	19.5%
22	Oxalosis	19.5%
23	Renal Insufficiency	19.5%
24	Holoprosencephaly	19%
25	Nail-Patella Syndrome	18.2%
26	Zellweger Syndrome	17.7%
27	Ectodermal Dysplasia	17.4%
28	Aplasia Cutis Congenita	17.4%
29	Prader-Willi Syndrome	17.3%
30	Aicardi's syndrome	17.2%
31	Tuberculosis, Renal	17.2%
32	Primary Ciliary Dyskinesia	17.1%
33	Diabetes Insipidus	16.9%
34	Hepatorenal Syndrome	16.9%
35	Diabetic Nephropathy	16.8%
36	Renal hypertension	16.8%
37	Renal Artery Obstruction	16.8%
38	Renal Artery Stenosis	16.8%
39	Nephrocalcinosis	16.7%
40	Rubinstein-Taybi Syndrome	16.6%
41	Urinary Bladder Diseases	16%
42	Ureteral Diseases	16%
43	Urethral Diseases	16%
44	Urination Disorders	16%
45	Urolithiasis	16%
46	Alstrom Syndrome	15.9%
47	Cockayne Syndrome	15.7%
48	Marfan Syndrome	15.7%
49	Prune Belly Syndrome	15.5%
50	Waardenburg Syndrome	15.5%
51	Kartagener Syndrome	15.3%
52	Kidney Neoplasm	15.3%
53	Bladder Exstrophy	14.4%
54	Epispadias	14.4%
55	Mobius Syndrome	14%
56	Urinary tract infection	13.8%
57	Ureterolithiasis	13.1%
58	Abnormalities, Drug-Induced	13.1%
59	Situs Inversus	13.1%
60	AIDS-Associated Nephropathy	13%
61	Bloom Syndrome	13%
62	Smith-Lemli-Opitz Syndrome	12.9%
63	Cystic Fibrosis	12.6%
64	Fetal Diseases	12.6%
65	Kidney Calculi	12%
66	Renal Aminoacidurias	11.9%
67	Fanconi Syndrome	11.9%
68	Pseudohypoaldosteronism	11.9%
69	Liddle Syndrome	11.9%
70	Glomerulonephritis	11.6%
71	Nephritis, Interstitial	11.6%
72	Lipoid nephrosis	11.6%
73	Nephrotic Syndrome	11.6%
74	Pyelitis	11.6%
75	Pyonephrosis	11.6%
76	Nephrogenic Diabetes Insipidus	11.6%
77	Congenital Nephrogenic Diabetes Insipidus	11.6%
78	Acute kidney injury	11.6%
79	Pyelonephritis	11.5%
80	Glycosuria, Renal	11.5%
81	Ichthyosis, X-Linked	11.5%
82	Fragile X Syndrome	11.4%
83	Eye Abnormalities	11.3%
84	Neoplastic Syndromes, Hereditary	11.3%
85	Cardiovascular Abnormalities	11.3%
86	Skin Abnormalities	11%
87	Lymphatic Abnormalities	11%
88	Congenital Microtia	11%
89	Hyperphosphaturia	11%
90	Multiple Epiphyseal Dysplasia	10.9%
91	Osteochondrodysplasias	10.9%
92	Pelger-Huet Anomaly	10.9%
93	Werner Syndrome	10.9%
94	Myasthenic Syndromes, Congenital	10.9%
95	Horseshoe Kidney	10.9%
96	Congenital diaphragmatic hernia	10.9%
97	Renal tubular acidosis	10.6%
98	Renal Osteodystrophy	10.6%
99	Renal rickets	10.6%
100	Hypospadias	10.6%
101	Bladder neck obstruction	10.5%
102	Nephroblastoma	10.1%
103	Azotemia	10.1%
104	Hypertension, Renovascular	9.9%
105	Anemia, Sickle Cell	9.7%
106	Thalassemia	9.7%
107	POEMS Syndrome	9.7%
108	Muscular Dystrophy, Duchenne	9.7%
109	Williams Syndrome	9.7%
110	Pyelocystitis	9.7%
111	Kallmann Syndrome	9.7%
112	Dwarfism	9.7%
113	Hermaphroditism	9.6%
114	Disorders of Sex Development	9.6%
115	Albinism	9.5%
116	Muscular Dystrophy	9.3%
117	Osteogenesis Imperfecta	9.3%
118	Anencephaly	9.2%
119	Xeroderma	9%
120	Basal Cell Nevus Syndrome	9%
121	Retinal Dysplasia	8.9%
122	Aniridia	8.8%
123	Cystitis	8.7%
124	Ureteral obstruction	8.7%
125	Ureterocele	8.7%
126	Urethral Obstruction	8.7%
127	Urethritis	8.7%
128	Vesico-Ureteral Reflux	8.7%
129	Urinary Retention	8.7%
130	Epidermolysis Bullosa	8.7%
131	Hemolytic-Uremic Syndrome	8.7%
132	Ureteral Calculi	8.5%
133	Autoimmune Lymphoproliferative Syndrome	8.3%
134	Meconium Aspiration Syndrome	8.3%
135	Maxillofacial Abnormalities	8.2%
136	Dural Arteriovenous Fistula	8.2%
137	Mesoblastic Nephroma	8.2%
138	Cystinuria	8.2%
139	Renal Cell Carcinoma	8.1%
140	Papillary Renal Cell Carcinoma	8.1%
141	Dextrocardia	8.1%
142	Angioedemas, Hereditary	8.1%
143	Urinary Bladder Fistula	8.1%
144	Bladder Neoplasm	8.1%
145	Ureteral Neoplasms	8.1%
146	Urethral Neoplasms	8.1%
147	Sjogren-Larsson Syndrome	8%
148	Cryptorchidism	7.8%
149	Wiskott-Aldrich Syndrome	7.8%
150	Familial Mediterranean Fever	7.7%
151	Twins, Conjoined	7.7%
152	Tuberous Sclerosis	7.7%
153	Balkan Nephropathy	7.7%
154	Focal glomerulosclerosis	7.7%
155	Kidney Failure, Chronic	7.7%
156	Bacteriuria	7.5%
157	Glycosuria	7.5%
158	Hematuria	7.5%
159	Oliguria	7.5%
160	Polyuria	7.5%
161	Proteinuria	7.5%
162	Pyuria	7.5%
163	Urinary Calculi	7.5%
164	Cystocele	7.5%
165	Urinary Incontinence	7.5%
166	Turner Syndrome	7.5%
167	Mucopolysaccharidosis II	7.5%
168	Menkes Kinky Hair Syndrome	7.4%
169	Rett Syndrome	7.3%
170	Abnormalities, Radiation-Induced	7.3%
171	Pseudoxanthoma Elasticum	7.2%
172	Myotonic Dystrophy	7.1%
173	Denys-Drash Syndrome	6.9%
174	Refsum Disease	6.9%
175	Glomerulonephritis, Membranoproliferative	6.8%
176	Classical Lissencephalies and Subcortical Band Heterotopias	6.7%
177	Scimitar Syndrome	6.7%
178	Enuresis	6.7%
179	Xeroderma Pigmentosum	6.6%
180	Anophthalmos	6.5%
181	Anus, Imperforate	6.5%
182	Hydranencephaly	6.5%
183	Microphthalmos	6.5%
184	Neural Tube Defects	6.5%
185	Tethered Cord Syndrome	6.5%
186	Iniencephaly	6.5%
187	Craniorachischisis	6.5%
188	Limb Deformities, Congenital	6.5%
189	Exencephaly	6.5%
190	Septo-Optic Dysplasia	6.5%
191	Craniofacial Abnormalities	6.5%
192	Cortical Dysplasia	6.5%
193	Malformations of Cortical Development	6.5%
194	Anorectal Malformations	6.5%
195	Abdominal Cramps	6.5%
196	Amniotic Band Syndrome	6.5%
197	Asphyxia Neonatorum	6.5%
198	Infant, Premature, Diseases	6.5%
199	Infantile Colic	6.5%
200	Amino Acid Metabolism, Inborn Errors	6.5%
201	Carbohydrate Metabolism, Inborn Errors	6.5%
202	Metal Metabolism, Inborn Errors	6.5%
203	Progeria	6.5%
204	Lysosomal Storage Diseases	6.5%
205	Cytochrome-c Oxidase Deficiency	6.5%
206	Peroxisomal Disorders	6.5%
207	Chorioamnionitis	6.4%
208	Neuronal Ceroid-Lipofuscinoses	6.4%
209	Sickle Cell Trait	6.4%
210	Klinefelter Syndrome	6.3%
211	Infertility	6.1%
212	Adrenoleukodystrophy	6.1%
213	Hepatolenticular Degeneration	6.1%
214	Deformity	6%
215	Genetic Diseases, Inborn	6%
216	Ataxia Telangiectasia	6%
217	Anti-Glomerular Basement Membrane Disease	5.9%
218	Amyloid Neuropathies, Familial	5.9%
219	Lupus Nephritis	5.8%
220	Gonadal Dysgenesis	5.8%
221	Adrenogenital Syndrome	5.8%
222	Ovotesticular Disorders of Sex Development	5.8%
223	Atypical Hemolytic Uremic Syndrome	5.8%
224	Hyperkeratosis, Epidermolytic	5.8%
225	Fetal Growth Retardation	5.7%
226	Craniosynostosis	5.7%
227	Syndactyly	5.7%
228	Brachycephaly	5.7%
229	Charcot-Marie-Tooth Disease	5.7%
230	Antley-Bixler Syndrome Phenotype	5.7%
231	Fetal Hypoxia	5.7%
232	Fetal Alcohol Spectrum Disorders	5.7%
233	Genital Diseases, Male	5.7%
234	Blepharophimosis	5.7%
235	Laryngostenosis	5.7%
236	Mouth Abnormalities	5.7%
237	Microcephaly	5.6%
238	Macrocephaly	5.6%
239	Cutis Laxa	5.6%
240	Esophageal Atresia	5.6%
241	Intestinal Atresia	5.6%
242	Pectus excavatum	5.6%
243	Klippel-Feil Syndrome	5.6%
244	Retinitis Pigmentosa	5.6%
245	Gastroschisis	5.6%
246	Synostosis	5.6%
247	Pigmentary retinopathy	5.6%
248	Acrodermatitis	5.6%
249	Lymphangiectasis, Intestinal	5.6%
250	Porokeratosis	5.6%
251	Gianotti-Crosti Syndrome	5.6%
252	Keratoderma, Palmoplantar	5.6%
253	Chronic granulomatous disease	5.5%
254	Pregnancy Complications	5.5%
255	Welander Distal Myopathy	5.5%
256	Acrocephalosyndactylia	5.5%
257	Anemia, Neonatal	5.5%
258	Persistent Fetal Circulation Syndrome	5.5%
259	Umbilical hernia	5.4%
260	Fabry Disease	5.4%
261	Urologic Neoplasms	5.3%
262	Familial Hypophosphatemic Rickets	5.3%
263	Noonan Syndrome	5.2%
264	Acute Chest Syndrome	5.2%
265	Hyperandrogenism	5.2%
266	Urethral Stenosis	5.2%
267	Urethral stricture	5.2%
268	Galactosemias	5.1%
269	Urea Cycle Disorders, Inborn	5.1%
270	Tyrosinemias	5.1%
271	Arthrogryposis	5%
272	Choanal Atresia	5%
273	Tracheobronchomegaly	5%
274	Laryngocele	5%
275	Choledochal Cyst	5%
276	Duane Retraction Syndrome	5%
277	Porphyrias, Hepatic	4.9%
278	Central Nervous System Cysts	4.9%
279	Dandy-Walker Syndrome	4.9%
280	Peutz-Jeghers Syndrome	4.9%
281	Myotonia Congenita	4.9%
282	Thrombasthenia	4.9%
283	Antithrombin III Deficiency	4.9%
284	Protein C Deficiency	4.9%
285	Brain Diseases, Metabolic, Inborn	4.9%
286	Afibrinogenemia	4.9%
287	Dystonia Musculorum Deformans	4.9%
288	Factor VII Deficiency	4.9%
289	Factor X Deficiency	4.9%
290	Factor XII Deficiency	4.9%
291	Hemophilia A	4.9%
292	Activated Protein C Resistance	4.9%
293	Factor II deficiency	4.9%
294	Factor VIII Deficiency	4.9%
295	Factor V deficiency	4.9%
296	Factor XI Deficiency	4.9%
297	Hypoprothrombinemias	4.9%
298	Fanconi Anemia	4.8%
299	Canavan Disease	4.8%
300	Alexander Disease	4.8%
301	Lafora Disease	4.8%
302	Unverricht-Lundborg Syndrome	4.8%
303	Anemia, Diamond-Blackfan	4.8%
304	Porencephaly	4.8%
305	Sexually Transmitted Diseases	4.8%
306	Neonatal Abstinence Syndrome	4.8%
307	Glycogen storage disease type II	4.8%
308	Cleft Palate	4.7%
309	Optic Atrophy, Hereditary, Leber	4.7%
310	Congenital nystagmus	4.7%
311	Toxoplasmosis, Congenital	4.6%
312	Syphilis, Congenital	4.6%
313	Genital Herpes	4.6%
314	Jaw Abnormalities	4.6%
315	Albuminuria	4.5%
316	Hemoglobinuria	4.5%
317	Multiple Endocrine Neoplasia	4.5%
318	Laryngomalacia	4.5%
319	Urge Incontinence	4.4%
320	Pectus carinatum	4.4%
321	Congenital Hypothyroidism	4.4%
322	Dermatitis, Atopic	4.4%
323	Endometriosis	4.3%
324	Uterine Diseases	4.3%
325	Vaginal Diseases	4.3%
326	Vulvar Diseases	4.3%
327	Endometrioma	4.3%
328	Amelia	4.3%
329	Arachnodactyly	4.3%
330	Ectopia Cordis	4.3%
331	Ectromelia	4.3%
332	Hemimelia	4.3%
333	Meningomyelocele	4.3%
334	Phocomelia	4.3%
335	Sirenomelia	4.3%
336	Spina Bifida	4.3%
337	Polydactyly	4.3%
338	Brachydactyly	4.3%
339	Plagiocephaly	4.3%
340	Lower Extremity Deformities, Congenital	4.3%
341	Upper Extremity Deformities, Congenital	4.3%
342	Single umbilical artery	4.3%
343	Alkaptonuria	4.3%
344	Glycogen Storage Disease	4.3%
345	Hypophosphatasia	4.3%
346	Propionic acidemia	4.3%
347	Dihydropyrimidine Dehydrogenase Deficiency	4.3%
348	Cystinosis	4.3%
349	Genital Neoplasms, Male	4.3%
350	Poland Syndrome	4.3%
351	Mucopolysaccharidosis III	4.3%
352	Congenital Hyperinsulinism	4.1%
353	Homocystinuria	4.1%
354	Leigh Disease	4.1%
355	Hydrops Fetalis	3.9%
356	Behcet Syndrome	3.9%
357	Diurnal Enuresis	3.9%
358	Aortic coarctation	3.7%
359	Cor Triatriatum	3.7%
360	Coronary Vessel Anomalies	3.7%
361	Dental Enamel Hypoplasia	3.7%
362	Patent ductus arteriosus	3.7%
363	Ebstein Anomaly	3.7%
364	Heart Septal Defects	3.7%
365	Hypodontia	3.7%
366	Macrostomia	3.7%
367	Meningocele	3.7%
368	Microstomia	3.7%
369	Tetralogy of Fallot	3.7%
370	Transposition of Great Vessels	3.7%
371	Hypoplastic Left Heart Syndrome	3.7%
372	May-Thurner Syndrome	3.7%
373	Encephalocele	3.7%
374	Craniofacial Dysostosis	3.7%
375	Hypolipoproteinemias	3.7%
376	Papillon-Lefevre Disease	3.7%
377	Wolff-Parkinson-White Syndrome	3.7%
378	Hyperlipidemia, Familial Combined	3.7%
379	Hyperlipoproteinemia Type III	3.7%
380	Gaucher Disease	3.7%
381	Genital Neoplasms, Female	3.6%
382	Huntington Disease	3.5%
383	Micrognathism	3.5%
384	Pierre Robin Syndrome	3.5%
385	Carbamoyl-Phosphate Synthase I Deficiency Disease	3.5%
386	Vesicovaginal Fistula	3.5%
387	Uterine Neoplasms	3.4%
388	Vaginal Neoplasms	3.4%
389	Vulvar Neoplasms	3.4%
390	Uterine Cancer	3.4%
391	Paralysis, Obstetric	3.3%
392	Retinopathy of Prematurity	3.3%
393	Familial Periodic Paralysis	3.3%
394	Long QT Syndrome	3.2%
395	Platybasia	3.2%
396	Tricuspid Atresia	3.2%
397	Arrhythmogenic Right Ventricular Dysplasia	3.2%
398	Bronchomalacia	3.2%
399	Tracheomalacia	3.2%
400	Ophthalmia Neonatorum	3.2%
401	Retrognathia	3.2%
402	Lactose Intolerance	3.2%
403	Variegate Porphyria	3.2%
404	Acute intermittent porphyria	3.2%
405	Porphyria Cutanea Tarda	3.2%
406	Bronchopulmonary Dysplasia	3.2%
407	Uterine Inversion	3.2%
408	Hyperhomocysteinemia	3.2%
409	Dermal Sinus	3.2%
410	Endometritis	3.2%
411	Spina Bifida Cystica	3.2%
412	Spina Bifida Occulta	3.2%
413	Lissencephaly	3.2%
414	Polymicrogyria	3.2%
415	Pachygyria	3.2%
416	Schizencephaly	3.2%
417	Periventricular Nodular Heterotopia	3.2%
418	Hyperlipoproteinemia Type IV	3.2%
419	Hyperlipoproteinemia Type V	3.2%
420	Glycogen Storage Disease Type I	3.2%
421	Glycogen Storage Disease Type V	3.2%
422	Tay-Sachs Disease	3.1%
423	Penile Neoplasms	3%
424	Prostatic Neoplasms	3%
425	Niemann-Pick Disease, Type C	3%
426	Adenomatous Polyposis Coli	3%
427	Prognathism	3%
428	Epididymitis	2.9%
429	Penile Diseases	2.9%
430	Prostatic Diseases	2.9%
431	Spermatic Cord Torsion	2.9%
432	Hemospermia	2.9%
433	Testicular Hydrocele	2.9%
434	Dyspareunia	2.9%
435	Gout	2.9%
436	Multiple Endocrine Neoplasia Type 1	2.9%
437	Pseudohypoparathyroidism	2.9%
438	Friedreich Ataxia	2.9%
439	Respiratory Distress Syndrome, Newborn	2.8%
440	Uterine Rupture	2.8%
441	Polyhydramnios	2.8%
442	Obstetric Labor Complications	2.8%
443	Ectopic Pregnancy	2.8%
444	Pregnancy, Prolonged	2.8%
445	Puerperal Disorders	2.8%
446	Oligohydramnios	2.8%
447	Prenatal Injuries	2.8%
448	Aortopulmonary Septal Defect	2.7%
449	Double Outlet Right Ventricle	2.7%
450	Endocardial Cushion Defects	2.7%
451	Fallopian Tube Neoplasms	2.7%
452	Myocardial bridging	2.7%
453	Aorticopulmonary Septal Defect	2.7%
454	Hypoalphalipoproteinemias	2.7%
455	Testicular Diseases	2.5%
456	Varicocele	2.5%
457	Spermatocele	2.5%
458	Abruptio Placentae	2.4%
459	Placenta Accreta	2.4%
460	Leukomalacia, Periventricular	2.4%
461	Polycystic Kidney Diseases	2.4%
462	Nesidioblastosis	2.4%
463	Hypokalemic periodic paralysis	2.4%
464	Mandibulofacial Dysostosis	2.4%
465	Romano-Ward Syndrome	2.4%
466	Endometrial Hyperplasia	2.4%
467	Pyometra	2.4%
468	Vaginitis	2.4%
469	Vulvitis	2.4%
470	Vaginal Discharge	2.4%
471	Vulvodynia	2.4%
472	Pregnancy Complications, Cardiovascular	2.4%
473	Pregnancy Complications, Neoplastic	2.4%
474	Salpingitis	2.4%
475	Vulvovaginitis	2.4%
476	Pregnancy Complications, Hematologic	2.3%
477	Pregnancy Complications, Infectious	2.3%
478	Fetal Death	2.3%
479	Perinatal death	2.3%
480	Morning Sickness	2.3%
481	Truncus Arteriosus, Persistent	2.3%
482	Goldenhar Syndrome	2.3%
483	ovarian neoplasm	2.2%
484	Arthritis, Gouty	2.1%
485	Puerperal Infection	2.1%
486	Postpartum Hemorrhage	2.1%
487	Oophoritis	2.1%
488	Endometrial Neoplasms	2%
489	Ovarian Diseases	2%
490	Adnexitis	2%
491	Pruritus Vulvae	2%
492	Uterine hemorrhage	2%
493	Vaginal Fistula	2%
494	Pelvic Inflammatory Disease	2%
495	Talipes	2%
496	Uterine Prolapse	2%
497	Vaginal Prolapse	2%
498	Gestational Diabetes	2%
499	Kernicterus	2%
500	MELAS Syndrome	2%
501	Arteriovenous fistula	1.9%
502	Uterine Cervical Incompetence	1.9%
503	Hyaline Membrane Disease	1.8%
504	Prostatic Neoplasms, Castration-Resistant	1.8%
505	Congenital clubfoot	1.8%
506	Vertical Talus	1.8%
507	Carcinoma, Endometrioid	1.7%
508	Testicular Neoplasms	1.6%
509	Balanitis	1.6%
510	Benign prostatic hypertrophy	1.6%
511	Phimosis	1.6%
512	Priapism	1.6%
513	prostatitis	1.6%
514	Prostatic Adenoma	1.6%
515	Benign Prostatic Hyperplasia	1.6%
516	Prostatic Hypertrophy	1.6%
517	Prostatic Hyperplasia	1.6%
518	Polycystic Kidney, Autosomal Dominant	1.6%
519	Abortion, Habitual	1.4%
520	Dystocia	1.4%
521	Eclampsia	1.4%
522	Fetal Membranes, Premature Rupture	1.4%
523	Placental Insufficiency	1.4%
524	Pre-Eclampsia	1.4%
525	Prenatal Exposure Delayed Effects	1.4%
526	HELLP Syndrome	1.4%
527	Placenta, Retained	1.4%
528	Uterine Cervicitis	1.4%
529	Leukorrhea	1.4%
530	Parametritis	1.4%
531	Candidiasis, Vulvovaginal	1.4%
532	Premature Ejaculation	1.4%
533	Erectile dysfunction	1.4%
534	Orchitis	1.3%
535	Chlamydia Infections	1.3%
536	Gonorrhea	1.3%
537	Abortion, Veterinary	1.3%
538	Pregnancy Complications, Parasitic	1.3%
539	Bacterial Vaginosis	1.2%
540	Lactation Disorder	1.2%
541	Mastitis	1.2%
542	Depression, Postpartum	1.2%
543	Embryo Loss	1.2%
544	Fetal Resorption	1.2%
545	Syphilis	1.2%
546	Hyperemesis Gravidarum	1.2%
547	Trichomonas Vaginitis	1.2%
548	Uterine Perforation	1.2%
549	Ovarian Hyperstimulation Syndrome	1.2%
550	granulosa cell tumor	1.2%
551	Carcinoma, Ovarian Epithelial	1.2%
552	Metrorrhagia	1.2%
553	Trophoblastic Neoplasms	1.1%
554	Embolism, Amniotic Fluid	1.1%
555	Corpus Luteum Cyst	1%
556	Ovarian Cysts	1%
557	Breech Presentation	1%
558	Anovulation	1%
559	Menorrhagia	1%
560	Stillbirth	1%
561	Premature Menopause	1%
562	Azoospermia	1%
563	Oligospermia	1%
564	Impotence, Vasculogenic	1%
565	Asthenozoospermia	1%
566	Teratozoospermia	1%
567	Aspermia	1%
568	Endometrial Stromal Sarcoma	0.9%
569	Lymphogranuloma Venereum	0.9%
570	Premature Birth	0.8%
571	Polycystic Ovary Syndrome	0.7%
572	Galactorrhea	0.7%
573	Leydig Cell Tumor	0.6%
574	Choriocarcinoma	0.5%
575	Hydatidiform Mole	0.3%

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