MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Dyslipidemias

(UMLS:C0242339)

Definition:: Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL.
UMLS ID:: C0242339
MeSH ID:: D050171

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.452.584.500

Synonym(s)

Dyslipidemias

DYSLIPIDEMIA

Dyslipidaemia

Dyslipidemia

High blood cholesterol/triglycerides

dyslipidemia

dyslipidemias

Associated Drug(s)

	Name	Reference(s)	Data Source
1	3,4-dihydroxyphenylethanol	19393637	CTD
2	Acetylcysteine	16814277	CTD
3	Acrylamide	29913234	CTD
4	Alcohols	24275070 26220516	CTD
5	Allopurinol	22426011	CTD
6	Alloxan	19393637 22138235	CTD
7	Aluminum	21439360	CTD
8	Arsenicals	22354675	CTD
9	Atazanavir Sulfate	27378623	CTD
10	Atorvastatin	View details 11472706 14605511 16230877 16988211 17156651	CTD
11	Bezafibrate	View details 1323073 8622389 9515185 15045684 16168052 16259526 17610533 21411093	CTD
12	Butyric Acid	27270450	CTD
13	Cadmium Compounds	23543441	CTD
14	Cannabidiol	31499052	CTD
15	Cholesterol	18230960	CTD
16	Clofibrate	9515185 16707586	CTD
17	Clozapine	16402076 18344722	CTD
18	Cyclosporine	17019561	CTD
19	Cyproterone Acetate	16323982	CTD
20	Danazol	6562983	CTD
21	Dexamethasone	19936461	CTD
22	Dichlorodiphenyl Dichloroethylene	21298090 26748080	CTD
23	Diosgenin	26408789	CTD
24	Docosahexaenoic Acids	19277604	CTD
25	Doxazosin	1981077 7705011	CTD
26	Doxorubicin	29474904	CTD
27	Eicosapentaenoic Acid	19277604	CTD
28	Everolimus	19955336	CTD
29	Ezetimibe, Simvastatin Drug Combination	19167588	CTD
30	Ezetimibe	View details 16690463 17002798 18230960 19019811 19167588	CTD
31	Fatty Acids, Omega-3	View details 12123627 16487912 18230960 19092644	CTD
32	Fenofibrate	View details 9515185 9681093 16259526 16707586 17201732 21411093 26973390	CTD
33	Fluvastatin	16446645	CTD
34	Fructose	View details 21212096 22426011 25679220 26973390	CTD
35	Gallic Acid	21078310	CTD
36	Gemfibrozil	View details 8941582 9515185 16259526 16707586	CTD
37	Glucose	12434198	CTD
38	Hydrogen Peroxide	21439360	CTD
39	LR-90	18317729	CTD
40	Letrozole	31295448	CTD
41	Lovastatin	16230877 17319473	CTD
42	Lynestrenol	6562983	CTD
43	MK-0524	21291812	CTD
44	Maneb	26210702	CTD
45	Metformin	27270450	CTD
46	Metoprolol	8761899	CTD
47	Monocrotophos	23228476	CTD
48	Niacin	View details 9824032 11472706 11701466 11765300 11835917 12099974 12123399 12200755 12804728 15219522 15307011 15929991 16230877 16487912 16690463 17002798 17156651 17190373 17302378 17319473 18230960 18422390 18471454 19019811 19092644 19166443 19331435 20518948 20948500 21098376 21121498 21276961 21291812	CTD
49	Nickel	24961859	CTD
50	Olanzapine	18344722	CTD
51	Oleanolic Acid	20188082	CTD
52	Pioglitazone	21484566 25679220	CTD
53	Polychlorinated Dibenzodioxins	21890736	CTD
54	Pravastatin	19167588	CTD
55	Prednisolone	1550394 7443604	CTD
56	Quercetin	18551111 23543441 29474904	CTD
57	Resveratrol	18930334 25025298	CTD
58	Risperidone	16965214	CTD
59	Ritonavir	27378623	CTD
60	Rosiglitazone	19277604 21484566	CTD
61	Rosuvastatin Calcium	20104931	CTD
62	Rutin	22426011	CTD
63	Saquinavir	27378623	CTD
64	Silymarin	24062023	CTD
65	Simvastatin	View details 14605511 15273860 16230877 16968827 18300778 18422390 18471454 20948500	CTD
66	Spironolactone	31295448	CTD
67	Streptozocin	View details 12123627 16037304 16523407 17177138 19695236 21078310 23927877 24140466 27270450 27488359 28946194 29382564 29988851 31499052	CTD
68	Taurine	22138235	CTD
69	Ticlopidine	1942649	CTD
70	Valproic Acid	19085528 19682024	CTD
71	Vitamin E	16487912	CTD
72	WAY-362450	19136377	CTD
73	alpha-naphthoflavone	27020609	CTD
74	amlodipine, atorvastatin drug combination	18174006	CTD
75	bisphenol A	27502578 27806752	CTD
76	boric acid	29913234	CTD
77	chiglitazar	16751799	CTD
78	ciprofibrate	9515185	CTD
79	cobaltiprotoporphyrin	25959017	CTD
80	eremanthin	19695236	CTD
81	esculetin	28946194	CTD
82	fibric acid	18629356	CTD
83	fumosorinone	25796170	CTD
84	gamma-oryzanol	16487912	CTD
85	geraniol	25679220	CTD
86	naringenin	23782265	CTD
87	naringin	22198281	CTD
88	perfluorobutanesulfonic acid	21705711	CTD
89	perfluorohexanesulfonic acid	21705711	CTD
90	perfluorooctane sulfonic acid	21705711	CTD
91	pimagedine	12123627	CTD
92	puag-haad	30577593	CTD
93	puerarin	23927877	CTD
94	sodium arsenite	24062023 26044777	CTD
95	tributyltin	30172001	CTD
96	zerumbone	24709573	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Xanthomatosis	46.7%
2	Xanthoma	46.7%
3	Lipodystrophy	33.3%
4	Lipomatosis	31.8%
5	Acid-Base Imbalance	31%
6	Calcium Metabolism Disorders	31%
7	Iron Metabolism Disorders	31%
8	Phosphorus Metabolism Disorders	31%
9	Water-Electrolyte Imbalance	31%
10	Mitochondrial Diseases	31%
11	Glucose Metabolism Disorders	31%
12	Wasting Syndrome	27.9%
13	Hypercalcemia	26.7%
14	Hypocalcemia	26.7%
15	Milk-Alkali Syndrome	26.7%
16	Adiposis Dolorosa	23.1%
17	Osteopenia	20.9%
18	Brain Diseases, Metabolic	20.5%
19	Acidosis	20%
20	Alkalosis	20%
21	Amyloidosis	20%
22	Calcinosis	20%
23	Hyperglycemia	20%
24	Hyperinsulinism	20%
25	Hyperkalemia	20%
26	Hypernatremia	20%
27	Hypoglycemia	20%
28	Hypokalemia	20%
29	Hyponatremia	20%
30	Hypophosphatemia	20%
31	Metabolic acidosis	20%
32	Iron Overload	20%
33	Nutrition Disorders	18.5%
34	Pseudohypoparathyroidism	18.1%
35	Rickets	17.3%
36	Brain Diseases, Metabolic, Inborn	15.9%
37	Neuronal Ceroid-Lipofuscinoses	15.5%
38	Leigh Disease	15.2%
39	Hyperhomocysteinemia	15.1%
40	Acidosis, Lactic	14.8%
41	Calciphylaxis	14.8%
42	Hemosiderosis	14.8%
43	Ketosis	14.8%
44	Ketonuria	14.8%
45	Ketoacidosis	14.8%
46	Ketonemia	14.8%
47	Vascular calcification	14.8%
48	Diabetes Mellitus	14.3%
49	Gaucher Disease	14.1%
50	HIV-Associated Lipodystrophy Syndrome	13.9%
51	Carbamoyl-Phosphate Synthase I Deficiency Disease	13.8%
52	Lactose Intolerance	13.7%
53	Dehydration	13.6%
54	Water Intoxication	13.6%
55	Werner Syndrome	13.6%
56	Diabetic Ketoacidosis	13.5%
57	Achlorhydria	13.3%
58	Amino Acid Metabolism, Inborn Errors	13.3%
59	Bloom Syndrome	13.3%
60	Carbohydrate Metabolism, Inborn Errors	13.3%
61	Metal Metabolism, Inborn Errors	13.3%
62	Osteoporosis	13.3%
63	Progeria	13.3%
64	Lysosomal Storage Diseases	13.3%
65	Bone Demineralization, Pathologic	13.3%
66	Cytochrome-c Oxidase Deficiency	13.3%
67	Peroxisomal Disorders	13.3%
68	Post-Traumatic Osteoporosis	13.3%
69	Celiac Disease	13.2%
70	Sprue, Tropical	13.2%
71	Steatorrhea	13.2%
72	Sprue	13.2%
73	Osteomalacia	13%
74	Tay-Sachs Disease	12.5%
75	Galactosemias	12.5%
76	Urea Cycle Disorders, Inborn	12.5%
77	Tyrosinemias	12.5%
78	Congenital Hyperinsulinism	12.2%
79	Niemann-Pick Disease, Type C	11.8%
80	Familial Hypophosphatemic Rickets	11.5%
81	Mitochondrial Encephalomyopathies	11.5%
82	Hyperphosphaturia	10.9%
83	Fabry Disease	10.9%
84	Glycogen storage disease type II	10.6%
85	Homocystinuria	10.4%
86	Child Nutrition Disorders	10.3%
87	Hypervitaminosis A	10.3%
88	Infant Nutrition Disorders	10.3%
89	Malnutrition	10.3%
90	Mitochondrial Myopathies	10.2%
91	Myelinolysis, Central Pontine	10.1%
92	Glycosuria	9.9%
93	Reye Syndrome	9.9%
94	Acidosis, Respiratory	9.9%
95	Alkalosis, Respiratory	9.9%
96	Hepatic Encephalopathy	9.8%
97	Nesidioblastosis	9.8%
98	Alkaptonuria	9.8%
99	Glycogen Storage Disease	9.8%
100	Hypophosphatasia	9.8%
101	Insulin Resistance	9.8%
102	Osteoporosis, Postmenopausal	9.8%
103	Propionic acidemia	9.8%
104	Dihydropyrimidine Dehydrogenase Deficiency	9.8%
105	Cystinosis	9.8%
106	Amyloid Neuropathies, Familial	9.8%
107	Renal tubular acidosis	9.7%
108	Sjogren-Larsson Syndrome	9.3%
109	HIV Wasting Syndrome	8.8%
110	Smith-Lemli-Opitz Syndrome	8.4%
111	MELAS Syndrome	8.2%
112	Renal Osteodystrophy	8.2%
113	Renal rickets	8.2%
114	Porphyrias, Hepatic	8.1%
115	Glycogen Storage Disease Type I	8.1%
116	Glycogen Storage Disease Type V	8.1%
117	Zellweger Syndrome	8%
118	Mucopolysaccharidosis III	8%
119	Adrenoleukodystrophy	8%
120	Necrobiosis Lipoidica Diabeticorum	7.9%
121	Menkes Kinky Hair Syndrome	7.9%
122	Fanconi Anemia	7.8%
123	Wernicke Encephalopathy	7.7%
124	Gestational Diabetes	7.7%
125	Latent Autoimmune Diabetes in Adults	7.7%
126	Diabetes Mellitus, Experimental	7.6%
127	Hepatolenticular Degeneration	7.4%
128	Nephrocalcinosis	7.4%
129	Tetany	7.4%
130	Hypolipoproteinemias	7.3%
131	Hyperlipidemia, Familial Combined	7.3%
132	Refsum Disease	7.3%
133	Hyperlipoproteinemia Type III	7.3%
134	Glycosuria, Renal	7.3%
135	Cerebral Amyloid Angiopathy	7.2%
136	Deficiency Diseases	6.7%
137	Starvation	6.7%
138	Refeeding Syndrome	6.7%
139	Friedreich Ataxia	6.5%
140	Hypoalphalipoproteinemias	6%
141	Familial Periodic Paralysis	6%
142	Primary amyloidosis	6%
143	Variegate Porphyria	5.9%
144	Acute intermittent porphyria	5.9%
145	Porphyria Cutanea Tarda	5.9%
146	Renal Aminoacidurias	5.8%
147	Fanconi Syndrome	5.8%
148	Pseudohypoaldosteronism	5.8%
149	Liddle Syndrome	5.8%
150	Hyperlipoproteinemia Type IV	5.8%
151	Hyperlipoproteinemia Type V	5.8%
152	Kernicterus	5.7%
153	Kearns-Sayre syndrome	5.7%
154	Cockayne Syndrome	5.7%
155	Canavan Disease	5.4%
156	Alexander Disease	5.4%
157	Mucopolysaccharidosis II	5.3%
158	Ataxia Telangiectasia	5.1%
159	Gout	5%
160	Amyotrophic Lateral Sclerosis	5%
161	Kwashiorkor	4.9%
162	Magnesium Deficiency	4.9%
163	Potassium Deficiency	4.9%
164	Protein Deficiency	4.9%
165	Avitaminosis	4.9%
166	Optic Atrophy, Hereditary, Leber	4.9%
167	Antley-Bixler Syndrome Phenotype	4.9%
168	Hypokalemic periodic paralysis	4.9%
169	Frontotemporal dementia	4.8%
170	Cystinuria	4.8%
171	Xeroderma Pigmentosum	4.5%
172	CREST Syndrome	4.2%
173	Ascorbic Acid Deficiency	4.1%
174	Vitamin A Deficiency	4.1%
175	Vitamin D Deficiency	4.1%
176	Vitamin E Deficiency	4.1%
177	Marasmus	4.1%
178	Arthritis, Gouty	4.1%
179	Albinism	3.7%
180	Folic Acid Deficiency	3.6%
181	Pellagra	3.6%
182	Thiamine Deficiency	3.6%
183	Vitamin B 12 Deficiency	3.6%
184	Vitamin B 6 Deficiency	3.6%
185	Pyridoxine Deficiency	3.6%
186	Beriberi	3.4%
187	Ichthyosis, X-Linked	3%
188	Obesity	2.6%
189	Obesity, Abdominal	2.4%
190	Anemia, Pernicious	2.3%
191	Vitamin K Deficiency	2.1%
192	Pediatric Obesity	1.9%
193	Scurvy	1.8%
194	Prader-Willi Syndrome	1.6%
195	Subacute Combined Degeneration	1.2%

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