MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Pyloric Stenosis

(UMLS:C0034194)

Definition:: Narrowing of the pyloric canal with varied etiology. A common form is due to muscle hypertrophy (PYLORIC STENOSIS, HYPERTROPHIC) seen in infants.
UMLS ID:: C0034194
MeSH ID:: D011707

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405.748.340.690

Synonym(s)

Pyloric Stenosis

Gastric Outlet Obstruction

PS - Pyloric stenosis

PYLORIC STENOSIS

Pyloric stenosis

Pylorus--Stenosis

gastric outflow obstruction

gastric outlet obstruction

pyloric obstruction

10.

pyloric stenoses

11.

pyloric stenosi

12.

pyloric stenosis

13.

pylorus; stenosis

14.

pylorus; stricture

15.

stenosis; pylorus

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Paroxetine	FAERS: 25	US FAERS
2	Fluoxetine	FAERS: 13	US FAERS
3	Ibuprofen	FAERS: 9	US FAERS
4	Isotretinoin	FAERS: 9	US FAERS
5	Erythromycin	FAERS: 8	OFFSIDES SIDER US FAERS
6	Levetiracetam	FAERS: 8	US FAERS
7	Azithromycin	FAERS: 7	SIDER US FAERS
8	Paroxetine	FAERS: 6	US FAERS
9	Valproic Acid	FAERS: 6	US FAERS
10	Arthrotec	FAERS: 5	US FAERS
11	Ciprofloxacin	FAERS: 5	US FAERS
12	carbidopa, levodopa drug combination	FAERS: 5	US FAERS
13	Tacrolimus	FAERS: 4	US FAERS
14	Venlafaxine Hydrochloride	FAERS: 4	US FAERS
15	Benicar hct	FAERS: 3	US FAERS
16	Fingolimod Hydrochloride	FAERS: 3	US FAERS
17	Fluoxetine	FAERS: 3	US FAERS
18	Glatiramer Acetate	FAERS: 3	US FAERS
19	Norgestrel	FAERS: 3	US FAERS
20	Omeprazole	FAERS: 3	US FAERS
21	Ondansetron	FAERS: 3	US FAERS
22	Sertraline	FAERS: 3	US FAERS
23	Aspirin	FAERS: 2	US FAERS
24	Citalopram	FAERS: 2	US FAERS
25	Dimethyl Fumarate	FAERS: 2	US FAERS
26	Erythromycin Ethylsuccinate	FAERS: 2	US FAERS
27	Orlistat	FAERS: 2	US FAERS
28	Pregabalin	FAERS: 2	US FAERS
29	Tiotropium Bromide	FAERS: 2	US FAERS
30	palbociclib	FAERS: 2	US FAERS
31	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1	US FAERS
32	Bosentan	FAERS: 1	US FAERS
33	Buprenorphine	FAERS: 1	US FAERS
34	Ceftriaxone	FAERS: 1	US FAERS
35	Citalopram	FAERS: 1	US FAERS
36	Cyclosporine	FAERS: 1	US FAERS
37	Diclofenac	FAERS: 1	US FAERS
38	Erythromycin Estolate	FAERS: 1	US FAERS
39	Iloprost	FAERS: 1	US FAERS
40	Imatinib Mesylate	FAERS: 1	US FAERS
41	Insulin Glargine	FAERS: 1	US FAERS
42	Lurasidone Hydrochloride	FAERS: 1	US FAERS
43	Mesalamine	FAERS: 1	US FAERS
44	Mycophenolic Acid	FAERS: 1	US FAERS
45	Omeprazole	FAERS: 1	US FAERS
46	Oxcarbazepine	FAERS: 1	US FAERS
47	Teriparatide	FAERS: 1	US FAERS
48	Topiramate	FAERS: 1	US FAERS
49	Trazodone	FAERS: 1	US FAERS
50	Warfarin	FAERS: 1	US FAERS
51	Zidovudine	FAERS: 1	OFFSIDES US FAERS
52	efavirenz	FAERS: 1	US FAERS
53	erythromycin stearate	FAERS: 1	US FAERS
54	niraparib	FAERS: 1	US FAERS
55	rofecoxib	FAERS: 1	US FAERS
56	sapropterin	FAERS: 1	US FAERS
57	Allopurinol		OFFSIDES
58	Atomoxetine Hydrochloride		OFFSIDES
59	Benzbromarone		OFFSIDES
60	Caffeine		OFFSIDES
61	Cefotaxime		OFFSIDES
62	Cilostazol		OFFSIDES
63	Cisapride		OFFSIDES
64	Clobazam		OFFSIDES
65	Desogestrel		OFFSIDES
66	Ertapenem		SIDER
67	Estradiol	Canada Vigilance: 1	Canada Vigilance
68	Ethosuximide		OFFSIDES
69	Fluconazole	Canada Vigilance: 1	Canada Vigilance
70	Fluvastatin		OFFSIDES
71	Lamotrigine		OFFSIDES
72	Mercaptopurine		OFFSIDES
73	Methyldopa		OFFSIDES
74	Metoclopramide		OFFSIDES
75	Nateglinide		OFFSIDES
76	Nelfinavir		OFFSIDES
77	Nitrazepam		OFFSIDES
78	Sodium picosulfate		OFFSIDES
79	Sumatriptan		OFFSIDES
80	Tretinoin		OFFSIDES
81	Vigabatrin		OFFSIDES
82	alfacalcidol		OFFSIDES
83	benidipine		OFFSIDES
84	epinastine		OFFSIDES
85	ferric citrate		OFFSIDES
86	ferrous fumarate		OFFSIDES
87	tegaserod		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Gastric Dilatation	34.4%
2	Gastritis	33%
3	Duodenogastric Reflux	29.3%
4	Peptic Ulcer	29.3%
5	Esophageal Diseases	25.4%
6	Gastroenteritis	25.4%
7	Intestinal Diseases	25.4%
8	Zollinger-Ellison syndrome	24.8%
9	Achlorhydria	23.1%
10	Gastric Antral Vascular Ectasia	23.1%
11	Gastroparesis	22.8%
12	Stomach Neoplasms	21.7%
13	Duodenal Ulcer	19.8%
14	Peptic Ulcer Perforation	19.8%
15	Gastric ulcer	19.8%
16	Dysentery	19.8%
17	Enteritis	19.8%
18	Enterocolitis	19.8%
19	Esophagitis	19.8%
20	Inflammatory Bowel Diseases	19.8%
21	Gastrointestinal Neoplasms	17.1%
22	Gastrointestinal Hemorrhage	16.9%
23	Tuberculosis, Gastrointestinal	16.5%
24	Biliary Tract Diseases	16.4%
25	Liver diseases	16.4%
26	Pancreatic Diseases	16.4%
27	Colitis	16.3%
28	Proctitis	16.3%
29	Dumping Syndrome	15.1%
30	Cecal Diseases	14.8%
31	Colonic Diseases	14.8%
32	Esophageal Stenosis	14.8%
33	Ileal Diseases	14.8%
34	Intestinal Obstruction	14.8%
35	Intestinal Perforation	14.8%
36	Jejunal Diseases	14.8%
37	Pneumatosis Cystoides Intestinalis	14.8%
38	Rectal Diseases	14.8%
39	Cronkhite-Canada Syndrome	14.8%
40	Intestinal Polyposis	14.8%
41	Duodenitis	14.5%
42	Ileitis	14.5%
43	Erosive Duodenitis	14.5%
44	Intestinal Neoplasms	13.8%
45	Proctocolitis	13.6%
46	Esophageal and Gastric Varices	13.2%
47	Crohn Disease	12.9%
48	Duodenal Obstruction	12.9%
49	Enterocolitis, Neutropenic	12.9%
50	Necrotizing Enterocolitis	12.9%
51	Appendicitis	12.3%
52	Mesenteric vascular insufficiency	12%
53	Colorectal Neoplasms	12%
54	Esophageal Atresia	11.8%
55	Intestinal Atresia	11.8%
56	Mesenteric Vascular Occlusion	11.8%
57	Intestinal Fistula	11.7%
58	Enterocutaneous Fistula	11.7%
59	Esophageal Neoplasms	11.5%
60	Digestive System Neoplasms	10.8%
61	Pouchitis	10.8%
62	Cecal Neoplasms	10.7%
63	Duodenal Neoplasms	10.7%
64	Esophageal Perforation	10.6%
65	Intestinal Diseases, Parasitic	10.6%
66	Barrett Esophagus	10.1%
67	Deglutition Disorders	10.1%
68	Gastrointestinal Stromal Tumors	9.8%
69	Peptic Ulcer Hemorrhage	9.8%
70	Rectal Fistula	9.7%
71	Anal Fistula	9.7%
72	Colonic Diseases, Functional	9.7%
73	Enterocolitis, Pseudomembranous	9.7%
74	Esophageal motility disorders	9.7%
75	Fecal Incontinence	9.7%
76	Fecal Impaction	9.7%
77	Intussusception	9.7%
78	Mallory-Weiss Syndrome	9.7%
79	Megacolon	9.7%
80	pseudomembranous colitis	9.7%
81	Ileus	9.7%
82	Dysentery, Bacillary	9.7%
83	Meconium ileus	9.7%
84	Colonic Pseudo-Obstruction	8.8%
85	Colitis, Ischemic	8.6%
86	Liver neoplasms	8.5%
87	Bile Duct Diseases	8.5%
88	Cholelithiasis	8.5%
89	Chylous Ascites	8.5%
90	Fatty Liver	8.5%
91	Hepatitis	8.5%
92	Portal Hypertension	8.5%
93	Liver Cirrhosis	8.5%
94	Pancreatic Fistula	8.5%
95	Pancreatic Insufficiency	8.5%
96	Pancreatitis	8.5%
97	Pneumoperitoneum	8.5%
98	Focal Nodular Hyperplasia	8.5%
99	Hepatic Insufficiency	8.5%
100	Steatohepatitis	8.5%
101	Appendiceal Neoplasms	7.9%
102	Colonic Neoplasms	7.9%
103	Rectal Neoplasms	7.9%
104	Anus Neoplasms	7.7%
105	Sigmoid Neoplasms	7.7%
106	Melena	7.5%
107	Hematemesis	7.3%
108	Esophageal Achalasia	7.2%
109	Anal Fissure	7.2%
110	Intestinal Pseudo-Obstruction	7.2%
111	Irritable Bowel Syndrome	7.2%
112	Superior Mesenteric Artery Syndrome	7.2%
113	Neurogenic Bowel	7.2%
114	Anal Ulcer	7.2%
115	Peritoneal Neoplasms	6.8%
116	Adenomatous Polyposis Coli	6.8%
117	Hemorrhoids	6.7%
118	Cholecystolithiasis	6.6%
119	Afferent Loop Syndrome	6.5%
120	Celiac Disease	6.5%
121	Short Bowel Syndrome	6.5%
122	Sprue, Tropical	6.5%
123	Steatorrhea	6.5%
124	Rectocele	6.5%
125	Sprue	6.5%
126	Diverticulitis	6.5%
127	Rectal Prolapse	6.5%
128	Biliary cirrhosis	6.1%
129	Liver Diseases, Parasitic	6%
130	Bile Duct Neoplasms	5.9%
131	gallbladder neoplasm	5.9%
132	Hepatic Veno-Occlusive Disease	5.7%
133	Pancreatic Cyst	5.7%
134	Peliosis Hepatis	5.7%
135	Hepatopulmonary Syndrome	5.7%
136	Pancreatic Neoplasm	5.7%
137	Anus, Imperforate	5.6%
138	Hemoperitoneum	5.6%
139	Hepatomegaly	5.6%
140	Mesenteric Panniculitis	5.6%
141	Panniculitis, Peritoneal	5.6%
142	Peritonitis	5.6%
143	Peritoneal Fibrosis	5.6%
144	Encapsulating Peritoneal Sclerosis	5.6%
145	Anorectal Malformations	5.6%
146	Biliary Fistula	5.6%
147	Gastric Fistula	5.6%
148	Hepatic Vein Thrombosis	5.5%
149	Liver Abscess	5.5%
150	Budd-Chiari Syndrome	5.5%
151	Choledochal Cyst	5.4%
152	Choledocholithiasis	5.4%
153	Giardiasis	5.1%
154	Diverticulum	5%
155	Diverticulosis	5%
156	Cholangitis	4.9%
157	Cholecystitis	4.9%
158	Cholestasis	4.9%
159	Common Bile Duct Diseases	4.9%
160	Hepatitis, Chronic	4.9%
161	Liver Failure	4.9%
162	Pancreatitis, Chronic	4.9%
163	Non-alcoholic Fatty Liver Disease	4.9%
164	Chronic active hepatitis	4.9%
165	Fatty Liver, Alcoholic	4.9%
166	Hepatitis, Alcoholic	4.9%
167	Liver Cirrhosis, Alcoholic	4.9%
168	Pruritus Ani	4.9%
169	Chemical and Drug Induced Liver Injury	4.3%
170	Hepatorenal Syndrome	4.2%
171	Laryngopharyngeal Reflux	4.1%
172	Peutz-Jeghers Syndrome	4%
173	Hepatocellular Adenoma	3.9%
174	Lactose Intolerance	3.9%
175	Hepatitis, Animal	3.5%
176	Hepatitis, Viral, Human	3.5%
177	Cystic Fibrosis	3.5%
178	Porphyrias, Hepatic	3.4%
179	Congenital Hyperinsulinism	3.4%
180	Liver Abscess, Amebic	3.3%
181	Liver Neoplasms, Experimental	3.3%
182	Liver Cirrhosis, Experimental	3.3%
183	Pancreatic Pseudocyst	3.3%
184	Pancreatitis, Alcoholic	3.3%
185	Cholestasis, Extrahepatic	3.2%
186	Biliary Dyskinesia	3.2%
187	Cholangitis, Sclerosing	3.2%
188	Liver Failure, Acute	3.2%
189	Acalculous Cholecystitis	3.2%
190	End Stage Liver Disease	3.2%
191	Cryptosporidiosis	2.9%
192	Fascioliasis	2.5%
193	Echinococcosis, Hepatic	2.5%
194	Chemical and Drug Induced Liver Injury, Chronic	2.5%
195	Reye Syndrome	2.5%
196	Carcinoma, Pancreatic Ductal	2.4%
197	Massive Hepatic Necrosis	2.4%
198	Emphysematous Cholecystitis	2.4%
199	Sphincter of Oddi Dysfunction	2.4%
200	Hepatitis B, Chronic	2.3%
201	Hepatitis C, Chronic	2.3%
202	Autoimmune hepatitis	2.2%
203	CREST Syndrome	2.1%
204	Nesidioblastosis	1.9%
205	Variegate Porphyria	1.9%
206	Acute intermittent porphyria	1.9%
207	Porphyria Cutanea Tarda	1.9%
208	insulinoma	1.8%
209	Gastrinoma	1.8%
210	Glucagonoma	1.8%
211	Hepatitis, Viral, Animal	1.8%
212	Hepatitis E	1.7%
213	Hepatitis B	1.7%
214	Hepatitis C	1.7%
215	Hepatitis A	1.7%
216	Hepatic Encephalopathy	1.6%
217	Vipoma	1.6%
218	Zellweger Syndrome	1.5%
219	Hepatolenticular Degeneration	1.4%
220	Rift Valley Fever	0.7%

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