MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hyperglycemia

(UMLS:C0020456)

Definition:: Abnormally high BLOOD GLUCOSE level.
UMLS ID:: C0020456
MeSH ID:: D006943

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.452.394.952

Synonym(s)

Hyperglycemia

Blood Glucose, High

Elevated Blood Glucose

Glucose, High Blood

HYPERGLYCAEMIA

HYPERGLYCEMIA

High Blood Glucose

High blood glucose

High blood sugar

10.

Hyperglycaemia

11.

Hyperglycaemia, NOS

12.

Hyperglycaemia, unspecified

13.

Hyperglycaemic disorder

Associated Drug(s)

	Name	Reference(s)	Data Source
1	1-Deoxynojirimycin	25446853	CTD
2	2,2',4,4'-tetrabromodiphenyl ether	27291303	CTD
3	2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol	30551545	CTD
4	3,3',4,5'-tetrahydroxystilbene	31323227	CTD
5	3,4,3',4'-tetrachlorobiphenyl	30935970	CTD
6	3,4-dihydroxyphenylethanol	19393637	CTD
7	4-phenylbutyric acid	30980806	CTD
8	4b,5,9b,10-tetrahydroindeno(1,2-b)indole	18823964	CTD
9	5,3'-dihydroxy-3,6,7,4',5'-pentamethoxyflavone	25986969	CTD
10	5-((2,4-dioxo-5-thiazolidinyl)methyl)-2-methoxy-N-((4-(trifluoromethyl)phenyl)methyl)benzamide	10098657 10582556	CTD
11	7-hydroxycoumarin	24661945	CTD
12	8-(4-benzenesulfonylamino)quinoline	7021128	CTD
13	8-(4-tolylsulfonylamino)quinoline	7021128	CTD
14	8-(methylsulfonylamino)quinoline	7021128	CTD
15	9-(8-azabicyclo(3.2.1)oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide	20616206	CTD
16	Acarbose	20667563	CTD
17	Acetylcysteine	16814277	CTD
18	Acrolein	28541489	CTD
19	Albuterol	View details 2575521 8098220 9311181 15232249	CTD
20	Alcohols	24275070	CTD
21	Alloxan	View details 12137914 19010315 19393637 21050842 21982801 22138235 23092809 26593071	CTD
22	Aminocaproic Acid	1117341	CTD
23	Aminophylline	1248788	CTD
24	Aspirin	1445173	CTD
25	Atorvastatin	26616219 28266800 30657622	CTD
26	Atropine	22305719	CTD
27	Barium	26689646	CTD
28	Berberine	22342832	CTD
29	Betamethasone	19249894	CTD
30	Bezafibrate	View details 10726910 11288046 17145126 17190905	CTD
31	Biotin	17496732	CTD
32	Brimonidine Tartrate	8097719 17195055	CTD
33	Cannabidiol	31499052	CTD
34	Capsaicin	1378463	CTD
35	Captan	29950287	CTD
36	Carboplatin	15493358	CTD
37	Carboxymethylcellulose Sodium	31063766	CTD
38	Carnosine	30802477	CTD
39	Chromium	12236580 20513351	CTD
40	Cimetidine	85850	CTD
41	Clioquinol	17434477	CTD
42	Clobetasol	19422381	CTD
43	Clofibrate	11918743	CTD
44	Clonidine	707001 3513563	CTD
45	Clozapine	View details 9034416 9669191 11125862 28266800	CTD
46	Copper	View details 15531641 23512809 24425765 26689646	CTD
47	Corticosterone	10197309	CTD
48	Dehydroepiandrosterone	11228057	CTD
49	Deoxyglucose	1378463	CTD
50	Desoximetasone	18591846	CTD
51	Dexamethasone	View details 1619017 8891570 11114284 11150359 11158452 11533345 15824971 19158320 19967395 21123945 21166656 23166830	CTD
52	Diazinon	22484362 23795780 30359674	CTD
53	Diazoxide	4299224 4875711 5086767	CTD
54	Dibutyl Phthalate	29526571 30940548	CTD
55	Dichlorodiphenyl Dichloroethylene	24582731 25541407 28572628	CTD
56	Dichlorvos	222008	CTD
57	Diethylhexyl Phthalate	30940548	CTD
58	Diosgenin	24001619 26408789	CTD
59	Diphenhydramine	17026994	CTD
60	Docetaxel	15839914	CTD
61	Doxycycline	9145823	CTD
62	Edaravone	18291360	CTD
63	Ellagic Acid	24877639	CTD
64	Enalaprilat	28266800	CTD
65	Enalapril	8591707 9861226	CTD
66	Epinephrine	View details 1032269 2989959 8097719 10925653 22305719	CTD
67	Estradiol	20801139 25859628	CTD
68	Estrone	3519326	CTD
69	Everolimus	16951235	CTD
70	Exenatide	28573460	CTD
71	Fatty Acids, Omega-3	12123627	CTD
72	Fructose	View details 17883899 19845545 21708140 22627169 24508943 25108154 25679220 26327248 27287418 30343038 30551545 31233715	CTD
73	GW 4064	23371517	CTD
74	Galactose	17211565	CTD
75	Gallic Acid	21078310 26341651	CTD
76	Genistein	28259689	CTD
77	Gliclazide	18380531 28330423	CTD
78	Glucosamine	20165829	CTD
79	Glucose	View details 11696579 12592403 19136606 22406263 23192364 29122539	CTD
80	Glutamine	31233715	CTD
81	Glyburide	View details 20363216 25724490 26700463 26748309 29223569 30582900 30817903	CTD
82	Hydrochlorothiazide	6337951 17928827 19792989	CTD
83	Hymecromone	24661945	CTD
84	Indapamide	1853463	CTD
85	Indinavir	12473836	CTD
86	Indomethacin	28266800	CTD
87	Isoflurane	29289695	CTD
88	Isoniazid	1445173	CTD
89	Isoproterenol	1032269	CTD
90	Ketamine	442425	CTD
91	Lithium	12773089	CTD
92	Losartan	30958922	CTD
93	Lycopene	22192907	CTD
94	Malathion	25180440	CTD
95	Manganese Compounds	26689646	CTD
96	Mercuric Chloride	30807803 31071422	CTD
97	Mercury Compounds	15531641	CTD
98	Metformin	View details 14984458 18377884 20869956 21457706 22342832 22627169 24946264 25108154 27551045 29421519 29614383 29991592 30551545 30958922 31100278	CTD
99	Methadone	2554359	CTD
100	Methylprednisolone	10925653	CTD
101	Metoprolol	3513563	CTD
102	Monocrotophos	22305719 23228476	CTD
103	N,N'-((5-(2-amino-5-(2-methylpropyl)-4-thiazolyl)-2-furanyl)phosphinylidene)bis(alanine) diethyl ester	21126019	CTD
104	N-(4-(2-(2-propylpyridin-4-yl)thiazol-4-yl)phenyl)methanesulfonamide	21561152	CTD
105	Nalidixic Acid	589309 1445173	CTD
106	Neostigmine	1350317	CTD
107	Niacinamide	View details 19059388 21382363 21630391 23406761 23466488 25849131 25999625 29247773 29421519	CTD
108	Niacin	8593127 20377808	CTD
109	Nickel	22444726 24961859	CTD
110	Nicotine	29155039	CTD
111	Octreotide	2111918 17897286	CTD
112	Ofloxacin	17026994	CTD
113	Olanzapine	11927762 12773089 17035934	CTD
114	Ozone	24103449 25838073 26732886	CTD
115	Paclitaxel	8626111 15493358	CTD
116	Paraoxon	22886793	CTD
117	Pentolinium Tartrate	1218171	CTD
118	Phentolamine	1350317 2989959 22305719	CTD
119	Phenytoin	5763660 6062284	CTD
120	Phlorhizin	1829330 16123366 22538082	CTD
121	Pioglitazone	View details 15655531 23811337 25679220 25796170 29247773 30343038	CTD
122	Prednisolone	19336998 19422381	CTD
123	Prednisone	3703509	CTD
124	Pregnenolone Carbonitrile	23588309 26616219	CTD
125	Propranolol	1032269 2575521 22305719	CTD
126	Pyruvaldehyde	11719831 23954466	CTD
127	Pyruvic Acid	19819963	CTD
128	Quercetin	View details 11834736 17211565 18262572 18551111 21462320 22713545 30372826	CTD
129	Resveratrol	View details 18675532 19059388 19819963 20424226 20974729 21439372 22309033 22627169 23406761 24036142 25108154 25191525 25999625 26006044 26700463	CTD
130	Rifampin	23588309	CTD
131	Risperidone	11927762 18278980	CTD
132	Ritodrine	6862070	CTD
133	Ritonavir	12473836	CTD
134	Rosiglitazone	View details 16757903 17555498 17697064 18983991 30218961	CTD
135	S-Nitroso-N-Acetylpenicillamine	7969812	CTD
136	SL 84.0418	8097719	CTD
137	Saponins	29247773	CTD
138	Sertraline	26593071	CTD
139	Sildenafil Citrate	19845545 26006044	CTD
140	Silymarin	22137898 29753610	CTD
141	Sirolimus	20358864	CTD
142	Sitagliptin Phosphate	23466488	CTD
143	Sodium Fluoride	19540901	CTD
144	Sodium Selenite	22476978	CTD
145	Sotalol	1032269	CTD
146	Streptozocin	View details 153477 1472065 1481903 2060723 3817338 7564366 7856696 8012888 8177907 9522273 9523171 9739991 10052637 10052646 10700396 11357483 11357882 11798618 12031899 12123627 12242689 12592403 15246841 15384252 15818713 16037304 16524951 16584726 16632197 17145126 17279352 17434477 17589825 17627248 17675792 18229453 18291360 18377884 18701828 18823964 18983991 19002579 19007766 19038238 19059388 19690068 19895808 20086057 20424226 20446767 20620209 20624991 20665664 20801139 20821229 21078310 21128592 21382363 21457706 21630391 21778425 21832210 22228707 22342832 22456468 22476978 22538082 22713545 22733486 22886793 22940631 23333261 23406761 23453443 23458895 23466488 23665085 23927877 24001619 24413998 24508943 24752916 24781736 24810525 24815820 24877639 24946264 25191525 25199697 25446853 25541178 25617480 25635252 25808216 25849131 25905778 25986969 25999625 26006044 26286521 26341651 26362499 26499206 26522834 26700463 26748309 26887929 27038876 27417257 27488359 27542954 27783111 28178614 28259689 28330423 28625491 28648635 28700904 28822685 28904557 28946194 29223569 29247773 29331653 29382564 29409856 29420703 29421519 29526571 29614383 29935216 29988851 30144451 30365938 30551545 30582900 30583000 30611788 30657622 30802477 30817903 30927557 30958922 30980806 31009641 31063766 31100278 31323227 31499052	CTD
147	Sucrose	31181236	CTD
148	Tacrolimus	View details 9193849 10616519 10918426 11296433	CTD
149	Taurine	22138235 23092809	CTD
150	Telmisartan	19171132	CTD
151	Terbutaline	6383045	CTD
152	Testosterone Propionate	17327368	CTD
153	Theophylline	718247 1445173 6506685	CTD
154	Thiophanate	29950287	CTD
155	Tocotrienols	20816776	CTD
156	Tolbutamide	18164698	CTD
157	Troglitazone	View details 8786734 9389757 9502777 11231916 11768731 11918743 14697232 20846491	CTD
158	UCF 101	19690068	CTD
159	Ursodeoxycholic Acid	22154323	CTD
160	Valproic Acid	6766992 12773089	CTD
161	Vanadates	1472065	CTD
162	Warfarin	27488359	CTD
163	Yohimbine	17195055	CTD
164	Zinc Sulfate	12137914	CTD
165	Ziram	29950287	CTD
166	acephate	19118596 22778074	CTD
167	acetamiprid	19069132	CTD
168	aluminum phosphide	9949483 18829736	CTD
169	alvocidib	12881391	CTD
170	amiloride, hydrochlorothiazide drug combination	8984227	CTD
171	amitraz	12046725 21288150	CTD
172	aromadedrin	30372826	CTD
173	asiatic acid	30802477	CTD
174	azoxystrobin	24726979	CTD
175	benazepril	11798618	CTD
176	benphothiamine	12592403	CTD
177	bis(4-hydroxyphenyl)sulfone	31344369	CTD
178	bisphenol A	View details 24705360 24959901 25168180 31344369	CTD
179	bisphenol F	30218961	CTD
180	caffeic acid phenethyl ester	24508943	CTD
181	caryophyllene	26748309 30343038	CTD
182	chlorpyrifos-ethyl	29950287	CTD
183	cinnamic aldehyde	20363216	CTD
184	cobaltiprotoporphyrin	22193921	CTD
185	corilagin	30582900	CTD
186	costunolide	19007766	CTD
187	crocin	29409856	CTD
188	cyanoginosin LR	29777831	CTD
189	decabromobiphenyl ether	23640034 28572024 30468867	CTD
190	ebselen	22484362 23795780	CTD
191	enhydrin	20211156	CTD
192	esculetin	28946194	CTD
193	falcarinol	29122539	CTD
194	fatostatin	19716478	CTD
195	fumosorinone	25796170	CTD
196	galangin	21708140	CTD
197	gastrodin	26634892	CTD
198	geraniol	25679220 28178614 28330423	CTD
199	gingerol	22285432	CTD
200	ginsenoside Rb1	20435129	CTD
201	ginsenoside Re	15949698 17885204	CTD
202	herbacetin	29653099	CTD
203	homocastasterone	28822685	CTD
204	honokiol	23811337	CTD
205	hydrazine	22305719	CTD
206	idebenone	28648635	CTD
207	kaempferol	18262572 30372826	CTD
208	lithospermate B	21295052	CTD
209	mangiferin	29223569	CTD
210	methyl isocyanate	8440870	CTD
211	miglitol	20667563	CTD
212	mustard oil	30927557	CTD
213	myrtenal	27417257	CTD
214	naringenin	View details 23192364 29223569 30372826 31063766	CTD
215	nymphayol	25499137	CTD
216	oltipraz	20086057	CTD
217	osthol	19682441	CTD
218	palbociclib	21610706	CTD
219	perfluorooctanoic acid	28947262	CTD
220	picolinic acid	17496732	CTD
221	pimagedine	12123627	CTD
222	pirinixic acid	20558911	CTD
223	procyanidin B2	25199697	CTD
224	pterostilbene	26700463	CTD
225	puerarin	23927877	CTD
226	quercetin 3-O-glucopyranoside	30817903	CTD
227	ragaglitazar	15655531	CTD
228	selenomethylselenocysteine	19010315	CTD
229	sodium arsenite	View details 16111841 22285432 24620584 25610880 26151952 29755549 30262289	CTD
230	sodium tungstate(VI)	11357483	CTD
231	sulindac sulfone	15839914	CTD
232	taxifolin	30372826	CTD
233	temsirolimus	20430774	CTD
234	tesaglitazar	12401884	CTD
235	thiacloprid	29950287	CTD
236	thymoquinone	29421519	CTD
237	triphenyltin hydroxide	6714370	CTD
238	triphenyltin	10522495	CTD
239	turmeric extract	25541178 27208389 28700904	CTD
240	ursolic acid	20869956	CTD
241	zopolrestat	27287418	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hyperinsulinism	46.7%
2	Hypoglycemia	46.7%
3	Diabetes Mellitus	33.3%
4	Acid-Base Imbalance	31%
5	Calcium Metabolism Disorders	31%
6	Iron Metabolism Disorders	31%
7	Phosphorus Metabolism Disorders	31%
8	Water-Electrolyte Imbalance	31%
9	Lipid Metabolism Disorders	31%
10	Mitochondrial Diseases	31%
11	Congenital Hyperinsulinism	28.4%
12	Wasting Syndrome	27.9%
13	Hypercalcemia	26.7%
14	Hypocalcemia	26.7%
15	Milk-Alkali Syndrome	26.7%
16	Diabetic Ketoacidosis	23.3%
17	Glycosuria	23.1%
18	Nesidioblastosis	22.9%
19	Insulin Resistance	22.8%
20	Osteopenia	20.9%
21	Brain Diseases, Metabolic	20.5%
22	Acidosis	20%
23	Alkalosis	20%
24	Amyloidosis	20%
25	Calcinosis	20%
26	Hyperkalemia	20%
27	Hypernatremia	20%
28	Hypokalemia	20%
29	Hyponatremia	20%
30	Lipodystrophy	20%
31	Xanthomatosis	20%
32	Hypophosphatemia	20%
33	Metabolic acidosis	20%
34	Dyslipidemias	20%
35	Iron Overload	20%
36	Xanthoma	20%
37	Nutrition Disorders	18.5%
38	Pseudohypoparathyroidism	18.1%
39	Gestational Diabetes	17.9%
40	Latent Autoimmune Diabetes in Adults	17.9%
41	Diabetes Mellitus, Experimental	17.6%
42	Rickets	17.3%
43	Brain Diseases, Metabolic, Inborn	15.9%
44	Leigh Disease	15.2%
45	Hyperhomocysteinemia	15.1%
46	Acidosis, Lactic	14.8%
47	Calciphylaxis	14.8%
48	Hemosiderosis	14.8%
49	Ketosis	14.8%
50	Ketonuria	14.8%
51	Ketoacidosis	14.8%
52	Ketonemia	14.8%
53	Vascular calcification	14.8%
54	Hypolipoproteinemias	14.6%
55	Hyperlipoproteinemia Type IV	14.5%
56	Hyperlipoproteinemia Type V	14.5%
57	Carbamoyl-Phosphate Synthase I Deficiency Disease	13.8%
58	Lactose Intolerance	13.7%
59	Dehydration	13.6%
60	Lipomatosis	13.6%
61	Water Intoxication	13.6%
62	Werner Syndrome	13.6%
63	Hyperlipidemia, Familial Combined	13.4%
64	Achlorhydria	13.3%
65	Amino Acid Metabolism, Inborn Errors	13.3%
66	Bloom Syndrome	13.3%
67	Carbohydrate Metabolism, Inborn Errors	13.3%
68	Metal Metabolism, Inborn Errors	13.3%
69	Osteoporosis	13.3%
70	Progeria	13.3%
71	Lysosomal Storage Diseases	13.3%
72	Bone Demineralization, Pathologic	13.3%
73	Cytochrome-c Oxidase Deficiency	13.3%
74	Peroxisomal Disorders	13.3%
75	Post-Traumatic Osteoporosis	13.3%
76	Celiac Disease	13.2%
77	Sprue, Tropical	13.2%
78	Steatorrhea	13.2%
79	Sprue	13.2%
80	Osteomalacia	13%
81	Hyperlipoproteinemia Type III	12.7%
82	Smith-Lemli-Opitz Syndrome	12.6%
83	Galactosemias	12.5%
84	Urea Cycle Disorders, Inborn	12.5%
85	Tyrosinemias	12.5%
86	Hypercholesterolemia	12.2%
87	Hyperlipoproteinemias	12.2%
88	Hypertriglyceridemia	12.2%
89	Glycosuria, Renal	12.1%
90	Hypoalphalipoproteinemias	12%
91	Familial Hypophosphatemic Rickets	11.5%
92	Mitochondrial Encephalomyopathies	11.5%
93	Gaucher Disease	10.9%
94	Hyperphosphaturia	10.9%
95	Glycogen storage disease type II	10.6%
96	Homocystinuria	10.4%
97	Child Nutrition Disorders	10.3%
98	Hypervitaminosis A	10.3%
99	Infant Nutrition Disorders	10.3%
100	Malnutrition	10.3%
101	Mitochondrial Myopathies	10.2%
102	Myelinolysis, Central Pontine	10.1%
103	Reye Syndrome	9.9%
104	Acidosis, Respiratory	9.9%
105	Adiposis Dolorosa	9.9%
106	Alkalosis, Respiratory	9.9%
107	Hepatic Encephalopathy	9.8%
108	Tay-Sachs Disease	9.8%
109	Alkaptonuria	9.8%
110	Glycogen Storage Disease	9.8%
111	Hypophosphatasia	9.8%
112	Osteoporosis, Postmenopausal	9.8%
113	Propionic acidemia	9.8%
114	Dihydropyrimidine Dehydrogenase Deficiency	9.8%
115	Cystinosis	9.8%
116	Amyloid Neuropathies, Familial	9.8%
117	Renal tubular acidosis	9.7%
118	Niemann-Pick Disease, Type C	9.3%
119	Neuronal Ceroid-Lipofuscinoses	9%
120	HIV Wasting Syndrome	8.8%
121	Fabry Disease	8.5%
122	HIV-Associated Lipodystrophy Syndrome	8.4%
123	MELAS Syndrome	8.2%
124	Renal Osteodystrophy	8.2%
125	Renal rickets	8.2%
126	Porphyrias, Hepatic	8.1%
127	Glycogen Storage Disease Type I	8.1%
128	Glycogen Storage Disease Type V	8.1%
129	Zellweger Syndrome	8%
130	Mucopolysaccharidosis III	8%
131	Adrenoleukodystrophy	8%
132	Necrobiosis Lipoidica Diabeticorum	7.9%
133	Menkes Kinky Hair Syndrome	7.9%
134	Fanconi Anemia	7.8%
135	Wernicke Encephalopathy	7.7%
136	Hepatolenticular Degeneration	7.4%
137	Nephrocalcinosis	7.4%
138	Tetany	7.4%
139	Refsum Disease	7.3%
140	Cerebral Amyloid Angiopathy	7.2%
141	Deficiency Diseases	6.7%
142	Starvation	6.7%
143	Refeeding Syndrome	6.7%
144	Friedreich Ataxia	6.5%
145	Familial Periodic Paralysis	6%
146	Primary amyloidosis	6%
147	Variegate Porphyria	5.9%
148	Acute intermittent porphyria	5.9%
149	Porphyria Cutanea Tarda	5.9%
150	Renal Aminoacidurias	5.8%
151	Fanconi Syndrome	5.8%
152	Pseudohypoaldosteronism	5.8%
153	Liddle Syndrome	5.8%
154	Kernicterus	5.7%
155	Kearns-Sayre syndrome	5.7%
156	Cockayne Syndrome	5.7%
157	Canavan Disease	5.4%
158	Alexander Disease	5.4%
159	Sjogren-Larsson Syndrome	5.4%
160	Mucopolysaccharidosis II	5.3%
161	Ataxia Telangiectasia	5.1%
162	Gout	5%
163	Amyotrophic Lateral Sclerosis	5%
164	Kwashiorkor	4.9%
165	Magnesium Deficiency	4.9%
166	Potassium Deficiency	4.9%
167	Protein Deficiency	4.9%
168	Avitaminosis	4.9%
169	Optic Atrophy, Hereditary, Leber	4.9%
170	Antley-Bixler Syndrome Phenotype	4.9%
171	Hypokalemic periodic paralysis	4.9%
172	Frontotemporal dementia	4.8%
173	Cystinuria	4.8%
174	Xeroderma Pigmentosum	4.5%
175	CREST Syndrome	4.2%
176	Ascorbic Acid Deficiency	4.1%
177	Vitamin A Deficiency	4.1%
178	Vitamin D Deficiency	4.1%
179	Vitamin E Deficiency	4.1%
180	Marasmus	4.1%
181	Arthritis, Gouty	4.1%
182	Albinism	3.7%
183	Folic Acid Deficiency	3.6%
184	Pellagra	3.6%
185	Thiamine Deficiency	3.6%
186	Vitamin B 12 Deficiency	3.6%
187	Vitamin B 6 Deficiency	3.6%
188	Pyridoxine Deficiency	3.6%
189	Beriberi	3.4%
190	Ichthyosis, X-Linked	3%
191	Obesity	2.6%
192	Obesity, Abdominal	2.4%
193	Anemia, Pernicious	2.3%
194	Vitamin K Deficiency	2.1%
195	Pediatric Obesity	1.9%
196	Scurvy	1.8%
197	Prader-Willi Syndrome	1.6%
198	Subacute Combined Degeneration	1.2%

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