MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hepatic Veno-Occlusive Disease

(UMLS:C0019156)

Definition:: Liver disease that is caused by injuries to the ENDOTHELIAL CELLS of the vessels and subendothelial EDEMA, but not by THROMBOSIS. Extracellular matrix, rich in FIBRONECTINS, is usually deposited around the HEPATIC VEINS leading to venous outflow occlusion and sinusoidal obstruction.
UMLS ID:: C0019156
MeSH ID:: D006504

Classification 1:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.552.360

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.460

Synonym(s)

Hepatic Veno-Occlusive Disease

Hepatic veno-occlusive disease

Liver Veno-Occlusive Disease

VENOOCCLUSIVE LIVER DISEASE

Veno-occlusive disease of the liver

Venoocclusive liver disease

disease (or disorder); liver, veno-occlusive [VOD]

disease liver veno-occlusive

hepatic veno-occlusive disease

10.

veno-occlusive disease hepatic

11.

venoocclusive liver disease

Associated Drug(s)

	Name	Reference(s)	Data Source
1	4-hydroxycyclophosphamide	16622453	CTD
2	Amifostine	11208352 15039909	CTD
3	Azathioprine	View details 2662036 2712618 3008617 3114679 3278593 7051531 8143956 8276346 8856241 9334484 9725784 11232733 11293451 12924643 16038116 17697264	CTD
4	Bilirubin	9334484	CTD
5	Busulfan	View details 1908340 2314142 2344115 3332186 8640171 10523796 10534061 11019834 11551021 12134100 12374454 12476274 12966370 14595385 14986274 15580502 17132762 18022574 18587430 18776081 19767780 20919852	CTD
6	Carboplatin	2189592 18587430 19701718	CTD
7	Carmustine	2189592	CTD
8	Ciprofloxacin	8832011	CTD
9	Cyclophosphamide	View details 1908340 2189592 3538535 7892168 8640171 9191535 10083875 11019834 12406916 14595385 14986274 15580502 16595573 16622453 19701718	CTD
10	Cyclosporine	3538535	CTD
11	Cytarabine	8640171 12497211 15981233	CTD
12	Dacarbazine	View details 528568 2278422 4093126 6503301 6786601 6986251 7379000	CTD
13	Dactinomycin	View details 1318536 2561915 7991279 9007466 9191535 9251728 9849483 11194540 11208352 11378345 15039909 15591910 19672975	CTD
14	Daunorubicin	18839274	CTD
15	Doxorubicin	2829807	CTD
16	Etoposide	8602625 8640171 18587430	CTD
17	Everolimus	19135948	CTD
18	Floxuridine	2531719	CTD
19	Folfox protocol	19019605	CTD
20	Idarubicin	12497211	CTD
21	Medroxyprogesterone Acetate	8832011	CTD
22	Melphalan	View details 2314142 10534061 14595385 18022574 19767780	CTD
23	Methotrexate	View details 1586725 8832011 18776081 18839274	CTD
24	Mitomycin	2829807	CTD
25	Monocrotaline	19387321 29908794 31470032	CTD
26	Norethindrone	9845522	CTD
27	Prednisone	18839274	CTD
28	Roxithromycin	16595573	CTD
29	Sirolimus	18776081	CTD
30	Tacrolimus	17697264 19135948	CTD
31	Thioguanine	View details 1068643 6957419 7053705 8496447 10914056 12451396 14510948 15472529 16856155 17015055 20124218 21272804	CTD
32	Thiotepa	View details 10534061 11019834 14595385 18587430 19767780	CTD
33	Tocopherols	3930760	CTD
34	Vancomycin	8832011	CTD
35	Vinblastine	15591910	CTD
36	Vincristine	View details 9191535 9251728 11194540 15981233 18839274 19701718	CTD
37	cobaltiprotoporphyrin	19387321	CTD
38	defibrotide	18696182	CTD
39	liquiritigenin	29908794	CTD
40	liquiritin	29908794	CTD
41	olprinone	19387321	CTD
42	turmeric extract	23845850	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Peliosis Hepatis	42.9%
2	Hepatic Vein Thrombosis	32.5%
3	Budd-Chiari Syndrome	32.5%
4	Aortic Aneurysm	31%
5	Aortitis	31%
6	Leriche Syndrome	31%
7	Periphlebitis	31%
8	Phlebitis	31%
9	Thromboangiitis Obliterans	31%
10	Thrombophlebitis	29.1%
11	Aneurysm	28.6%
12	Angiomatosis	28.6%
13	Aortic Diseases	28.6%
14	Arterial Occlusive Diseases	28.6%
15	Fatty Liver	28.6%
16	Hepatitis	28.6%
17	Hyperemia	28.6%
18	Portal Hypertension	28.6%
19	Hypotension	28.6%
20	Liver Cirrhosis	28.6%
21	Superior Vena Cava Syndrome	28.6%
22	Telangiectasis	28.6%
23	Vasculitis	28.6%
24	Venous Insufficiency	28.6%
25	Peripheral Vascular Diseases	28.6%
26	Embolism and Thrombosis	28.6%
27	Angiodysplasia	28.6%
28	Myocardial Ischemia	28.6%
29	Focal Nodular Hyperplasia	28.6%
30	Capillary Leak Syndrome	28.6%
31	Hepatic Insufficiency	28.6%
32	Prehypertension	28.6%
33	Steatohepatitis	28.6%
34	Postphlebitic Syndrome	28.2%
35	Biliary cirrhosis	27.5%
36	Mesenteric vascular insufficiency	26.8%
37	Retinal Vein Occlusion	26.1%
38	Blue Toe Syndrome	26.1%
39	Coronary Aneurysm	25.7%
40	Aortic Rupture	25.4%
41	Aortic Aneurysm, Abdominal	25.4%
42	Aortic Aneurysm, Thoracic	25.4%
43	Hemorrhoids	25.2%
44	Malignant Atrophic Papulosis	24.7%
45	Shwartzman Phenomenon	24.5%
46	Fatty Liver, Alcoholic	24.4%
47	Hepatitis, Alcoholic	24.4%
48	Liver Cirrhosis, Alcoholic	24.4%
49	Carotid Artery Thrombosis	24%
50	Coronary Thrombosis	23.5%
51	Coronary Artery Disease	23.5%
52	Myocardial Reperfusion Injury	23.2%
53	Colitis, Ischemic	22.9%
54	Liver neoplasms	22.5%
55	Intracranial Embolism and Thrombosis	22.3%
56	Carotid Stenosis	22.2%
57	Intracranial Aneurysm	22.2%
58	Liver Diseases, Parasitic	22.2%
59	Mesenteric Vascular Occlusion	22.2%
60	Vascular System Injuries	22.2%
61	Moyamoya Disease	22%
62	Compartment syndromes	21.4%
63	Varicocele	21.4%
64	Hepatopulmonary Syndrome	21.4%
65	Cerebrovascular Disorders	21.1%
66	Diabetic Angiopathies	21.1%
67	Hepatomegaly	21.1%
68	Reperfusion Injury	21.1%
69	Splenic Infarction	21.1%
70	Cerebrovascular Insufficiency	21.1%
71	Vascular Neoplasms	21.1%
72	Spinal Cord Vascular Diseases	21.1%
73	Vasoplegia	21.1%
74	Aneurysm, Dissecting	20.9%
75	Arteriosclerosis	20.9%
76	Arteritis	20.9%
77	Embolism	20.9%
78	Erythromelalgia	20.9%
79	Fibromuscular Dysplasia	20.9%
80	Hepatitis, Chronic	20.9%
81	Malignant Hypertension	20.9%
82	Raynaud Disease	20.9%
83	Thromboembolism	20.9%
84	Thrombosis	20.9%
85	Essential Hypertension	20.9%
86	Liver Failure	20.9%
87	Aneurysm, Ruptured	20.9%
88	Iliac Aneurysm	20.9%
89	Pulmonary artery stenosis	20.9%
90	White Coat Hypertension	20.9%
91	Systemic Vasculitis	20.9%
92	Non-alcoholic Fatty Liver Disease	20.9%
93	Chronic active hepatitis	20.9%
94	Embolus	20.9%
95	Thoracic Outlet Syndrome	20.9%
96	Liver Abscess	20.8%
97	Coronary heart disease	20.7%
98	Esophageal and Gastric Varices	20.7%
99	Myocardial Infarction	20.7%
100	Gastric Antral Vascular Ectasia	20.7%
101	Acute Coronary Syndrome	20.7%
102	Polyarteritis Nodosa	20.3%
103	Takayasu Arteritis	20.3%
104	Intracranial Arteriosclerosis	20.1%
105	Cerebral Atherosclerosis	20.1%
106	Cerebral Arteriosclerosis	20.1%
107	Arteriovenous fistula	19.1%
108	Cerebral Thrombosis	19%
109	Intracranial Embolism	19%
110	Intracranial Thrombosis	19%
111	Vasculitis, Central Nervous System	17.6%
112	Liver Abscess, Amebic	17.5%
113	Hand-Arm Vibration Syndrome	17.4%
114	Sinus Thrombosis, Intracranial	17.4%
115	Arteriosclerosis Obliterans	17.2%
116	Atherosclerosis	17.2%
117	Air Embolism	17.2%
118	Endarteritis	17.2%
119	Venous Thrombosis	17.2%
120	Deep Vein Thrombosis	17.2%
121	Liver Failure, Acute	17.2%
122	End Stage Liver Disease	17.2%
123	Venous Thromboembolism	17.2%
124	Chemical and Drug Induced Liver Injury	17.1%
125	Coronary Occlusion	16.9%
126	Microvascular Angina	16.9%
127	Coronary Stenosis	16.9%
128	ST segment elevation myocardial infarction	16.9%
129	Optic Neuropathy, Ischemic	16.9%
130	Anterior Ischemic Optic Neuropathy	16.9%
131	Lemierre Syndrome	16.7%
132	Kounis Syndrome	16.7%
133	Cavernous Sinus Thrombosis	16.6%
134	Sagittal Sinus Thrombosis	16.6%
135	Giant Cell Arteritis	16.6%
136	Brain Infarction	16.6%
137	Temporal Arteritis	16.6%
138	Hepatorenal Syndrome	16.6%
139	Angioedema	16.4%
140	Hepatitis, Animal	16.4%
141	Hepatitis, Viral, Human	16.4%
142	May-Thurner Syndrome	16.3%
143	Angina Pectoris	16.3%
144	Hepatitis B, Chronic	15.9%
145	Hepatitis C, Chronic	15.9%
146	Embolism, Amniotic Fluid	15.9%
147	Infarction, Middle Cerebral Artery	15.8%
148	Infarction, Anterior Cerebral Artery	15.8%
149	Infarction, Posterior Cerebral Artery	15.8%
150	Retinal Artery Occlusion	15.8%
151	Retinal Vasculitis	15.8%
152	Hypertensive Retinopathy	15.8%
153	CREST Syndrome	15.5%
154	Anterior Compartment Syndrome	15.5%
155	Liver Cirrhosis, Experimental	15.5%
156	Vasculitis, Leukocytoclastic, Cutaneous	15.5%
157	Abdominal Compartment Syndrome	15.5%
158	Massive Hepatic Necrosis	15.4%
159	Carotid Artery Diseases	15.4%
160	Brain Ischemia	15.4%
161	Hypotension, Orthostatic	15.4%
162	Cerebrovascular accident	15.4%
163	Varicose Ulcer	15.4%
164	Vasospasm, Intracranial	15.4%
165	Spinal Cord Ischemia	15.4%
166	Intracranial Arterial Diseases	15.4%
167	Primary Graft Dysfunction	15.4%
168	Post-Exercise Hypotension	15.4%
169	Subarachnoid Hemorrhage, Traumatic	15.2%
170	Carotid Artery, Internal, Dissection	15.2%
171	Coronary Restenosis	15.1%
172	Biliary Tract Diseases	15%
173	Gastrointestinal Diseases	15%
174	Heart Diseases	15%
175	Pancreatic Diseases	15%
176	Cerebral Infarction	14.8%
177	Brain Stem Infarctions	14.8%
178	Vertebral Artery Dissection	14.3%
179	Lateral Medullary Syndrome	13.9%
180	Porphyrias, Hepatic	13.8%
181	Shock, Cardiogenic	13.5%
182	Hepatocellular Adenoma	13.5%
183	Angina, Unstable	13.4%
184	Intermittent Claudication	13%
185	Pulmonary Embolism	13%
186	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	13%
187	Autoimmune hepatitis	13%
188	Scimitar Syndrome	13%
189	No-Reflow Phenomenon	12.8%
190	Cerebral Arterial Diseases	12.7%
191	Vertebrobasilar Insufficiency	12.7%
192	Anterior Spinal Artery Syndrome	12.7%
193	Basilar Artery Stenosis	12.7%
194	Vertebral Artery Stenosis	12.7%
195	Intracranial Hemorrhage, Hypertensive	12.7%
196	Transient Cerebral Ischemia	12.7%
197	Fascioliasis	12.5%
198	Mucocutaneous Lymph Node Syndrome	12.5%
199	Zollinger-Ellison syndrome	12.5%
200	Carotid Artery Injuries	12.4%
201	Diabetic Retinopathy	12.4%
202	Echinococcosis, Hepatic	12.4%
203	Sturge-Weber Syndrome	12.4%
204	Livedo Reticularis	12.3%
205	Chemical and Drug Induced Liver Injury, Chronic	12.3%
206	Renal hypertension	12.2%
207	Renal Artery Obstruction	12.2%
208	Renal Artery Stenosis	12.2%
209	Reye Syndrome	12.2%
210	Hemangioma, Cavernous	12.2%
211	Basal Ganglia Cerebrovascular Disease	12.2%
212	Vascular Headaches	12.1%
213	Scurvy	12.1%
214	Angina Pectoris, Variant	11.9%
215	Liver Neoplasms, Experimental	11.7%
216	Basal Ganglia Hemorrhage	11.6%
217	Pulmonary Infarction	11.5%
218	Subclavian Steal Syndrome	11.3%
219	Gastrointestinal Neoplasms	11.3%
220	Pancreatic Fistula	11.2%
221	Digestive System Neoplasms	11.1%
222	Pregnancy Complications, Cardiovascular	11.1%
223	Cardiovascular Abnormalities	11.1%
224	Proctocolitis	11.1%
225	Hepatitis, Viral, Animal	10.8%
226	Putaminal Hemorrhage	10.7%
227	Hepatitis E	10.5%
228	Aortic Valve Stenosis	10.3%
229	Cardiomyopathy, Dilated	10.3%
230	Dysentery	10.3%
231	Enteritis	10.3%
232	Enterocolitis	10.3%
233	Esophagitis	10.3%
234	Gastritis	10.3%
235	Hepatitis B	10.3%
236	Hepatitis C	10.3%
237	Inflammatory Bowel Diseases	10.3%
238	Pulmonary Valve Stenosis	10.3%
239	Cholecystolithiasis	10.3%
240	Colorectal Neoplasms	10.3%
241	Hepatitis A	10.3%
242	Ischemic contracture	10.2%
243	Bile Duct Neoplasms	10.2%
244	gallbladder neoplasm	10.2%
245	Angioedemas, Hereditary	10.2%
246	Intestinal Neoplasms	10.2%
247	Stomach Neoplasms	10.2%
248	Tricuspid Atresia	10.2%
249	Arrhythmogenic Right Ventricular Dysplasia	10.2%
250	Hepatic Encephalopathy	10.1%
251	Cryoglobulinemia	10.1%
252	Leukomalacia, Periventricular	10.1%
253	Duodenitis	10.1%
254	Ileitis	10.1%
255	Erosive Duodenitis	10.1%
256	Variegate Porphyria	10.1%
257	Acute intermittent porphyria	10.1%
258	Porphyria Cutanea Tarda	10.1%
259	Hypertension, Renovascular	10%
260	Subarachnoid Hemorrhage	10%
261	Hypoxia-Ischemia, Brain	10%
262	Cerebral Hemorrhage	10%
263	Diabetic Foot	10%
264	Hereditary Angioedema Type III	10%
265	Hereditary Angioedema Types I and II	10%
266	Dementia, Vascular	9.9%
267	Esophageal Atresia	9.7%
268	Intestinal Atresia	9.7%
269	Intestinal Fistula	9.7%
270	Enterocutaneous Fistula	9.7%
271	Bile Duct Diseases	9.5%
272	Cardiac Tamponade	9.5%
273	Cholelithiasis	9.5%
274	Chylous Ascites	9.5%
275	Endocarditis	9.5%
276	Esophageal Diseases	9.5%
277	Gastroenteritis	9.5%
278	Cardiac Arrest	9.5%
279	Heart failure	9.5%
280	Intestinal Diseases	9.5%
281	Pancreatic Insufficiency	9.5%
282	Pancreatitis	9.5%
283	Pericardial effusion	9.5%
284	Pericarditis	9.5%
285	Pneumopericardium	9.5%
286	Pneumoperitoneum	9.5%
287	Cor pulmonale	9.5%
288	Stomach Diseases	9.5%
289	Ventricular Outflow Obstruction	9.5%
290	Ventricular Dysfunction	9.5%
291	Cardiomyopathies	9.5%
292	Pleuropericarditis	9.5%
293	Cecal Neoplasms	9.5%
294	Duodenal Neoplasms	9.5%
295	Colitis	9.4%
296	Duodenogastric Reflux	9.4%
297	Peptic Ulcer	9.4%
298	Proctitis	9.4%
299	Choledocholithiasis	9.4%
300	Peritoneal Neoplasms	9.3%
301	Granulomatosis with polyangiitis	9.2%
302	Cerebral Amyloid Angiopathy	9%
303	Pouchitis	9%
304	Hypertrophic Cardiomyopathy	8.9%
305	Hypertrophic obstructive cardiomyopathy	8.9%
306	Rectal Fistula	8.9%
307	Anal Fistula	8.9%
308	Anus Neoplasms	8.7%
309	Sigmoid Neoplasms	8.7%
310	Esophageal Neoplasms	8.7%
311	Shy-Drager Syndrome	8.6%
312	Purpura, Hyperglobulinemic	8.6%
313	Supravalvular aortic stenosis	8.5%
314	Crohn Disease	8.5%
315	Duodenal Obstruction	8.5%
316	Lown-Ganong-Levine Syndrome	8.5%
317	Enterocolitis, Neutropenic	8.5%
318	Necrotizing Enterocolitis	8.5%
319	Pituitary Apoplexy	8.4%
320	Appendiceal Neoplasms	8.4%
321	Colonic Neoplasms	8.4%
322	Rectal Neoplasms	8.4%
323	Heart Block	8.2%
324	Tachycardia	8.2%
325	Tachyarrhythmia	8.2%
326	Aortic coarctation	8.2%
327	Cor Triatriatum	8.2%
328	Coronary Vessel Anomalies	8.2%
329	Patent ductus arteriosus	8.2%
330	Ebstein Anomaly	8.2%
331	Heart Septal Defects	8.2%
332	Tetralogy of Fallot	8.2%
333	Transposition of Great Vessels	8.2%
334	Hypoplastic Left Heart Syndrome	8.2%
335	Gastrointestinal Stromal Tumors	8.2%
336	Choledochal Cyst	8.1%
337	Bacterial Endocarditis	8.1%
338	Duodenal Ulcer	8%
339	Peptic Ulcer Perforation	8%
340	Gastric ulcer	8%
341	Pancreatic Neoplasm	8%
342	Behcet Syndrome	7.6%
343	Lupus Vasculitis, Central Nervous System	7.6%
344	Waldenstrom Macroglobulinemia	7.6%
345	Multiple Myeloma	7.6%
346	Appendicitis	7.5%
347	Colonic Pseudo-Obstruction	7.3%
348	Rheumatoid Vasculitis	7.2%
349	Pancreatic Cyst	7.1%
350	Cardiac Output, High	7.1%
351	Myocardial Stunning	7.1%
352	Low Cardiac Output Syndrome	7.1%
353	Sick Sinus Syndrome	7.1%
354	Anus, Imperforate	7%
355	Gastrointestinal Hemorrhage	7%
356	Cardiomegaly	7%
357	Hemoperitoneum	7%
358	Mesenteric Panniculitis	7%
359	Panniculitis, Peritoneal	7%
360	Peritonitis	7%
361	Postpericardiotomy Syndrome	7%
362	Peritoneal Fibrosis	7%
363	Cardiac Hypertrophy	7%
364	Encapsulating Peritoneal Sclerosis	7%
365	Anorectal Malformations	7%
366	Aortic Valve Insufficiency	7%
367	Restrictive cardiomyopathy	7%
368	Cecal Diseases	7%
369	Cholangitis	7%
370	Cholecystitis	7%
371	Cholestasis	7%
372	Colonic Diseases	7%
373	Common Bile Duct Diseases	7%
374	Endocardial Fibroelastosis	7%
375	Esophageal Stenosis	7%
376	Heart Rupture, Post-Infarction	7%
377	Ileal Diseases	7%
378	Intestinal Obstruction	7%
379	Intestinal Perforation	7%
380	Jejunal Diseases	7%
381	Mitral Valve Insufficiency	7%
382	Mitral Valve Stenosis	7%
383	Myocarditis	7%
384	Pericarditis, Constrictive	7%
385	Pneumatosis Cystoides Intestinalis	7%
386	Pulmonary Valve Insufficiency	7%
387	Rectal Diseases	7%
388	Gastric Dilatation	7%
389	Tricuspid Valve Insufficiency	7%
390	Tricuspid Valve Stenosis	7%
391	Pancreatitis, Chronic	7%
392	Gastric outlet obstruction	7%
393	Ventricular Dysfunction, Left	7%
394	Right Ventricular Dysfunction	7%
395	Cronkhite-Canada Syndrome	7%
396	Endomyocardial Fibrosis	7%
397	Carditis	7%
398	Heart Failure, Systolic	7%
399	Heart Failure, Diastolic	7%
400	Intestinal Polyposis	7%
401	Biliary Fistula	7%
402	Gastric Fistula	7%
403	Rheumatic Heart Disease	6.9%
404	Tuberculosis, Gastrointestinal	6.9%
405	Adenomatous Polyposis Coli	6.9%
406	Ataxia Telangiectasia	6.8%
407	Pseudoxanthoma Elasticum	6.8%
408	Dextrocardia	6.8%
409	Long QT Syndrome	6.8%
410	Adams-Stokes Syndrome	6.7%
411	Atrioventricular Block	6.7%
412	Bundle-Branch Block	6.7%
413	Enterocolitis, Pseudomembranous	6.7%
414	Atrial Premature Complexes	6.7%
415	Sinoatrial Block	6.7%
416	Tachycardia, Paroxysmal	6.7%
417	Supraventricular tachycardia	6.7%
418	Tachycardia, Ventricular	6.7%
419	Wolff-Parkinson-White Syndrome	6.7%
420	Tachycardia, Reciprocating	6.7%
421	pseudomembranous colitis	6.7%
422	Dysentery, Bacillary	6.7%
423	Aortopulmonary Septal Defect	6.7%
424	Double Outlet Right Ventricle	6.7%
425	Endocardial Cushion Defects	6.7%
426	Myocardial bridging	6.7%
427	Aorticopulmonary Septal Defect	6.7%
428	Zellweger Syndrome	6.6%
429	Hepatolenticular Degeneration	6.1%
430	Tachycardia, Atrioventricular Nodal Reentry	6%
431	Tachycardia, Ectopic Atrial	6%
432	Tachycardia, Ectopic Junctional	6%
433	Sinus Tachycardia	6%
434	Torsades de Pointes	6%
435	Accelerated Idioventricular Rhythm	6%
436	Truncus Arteriosus, Persistent	6%
437	Rift Valley Fever	5.8%
438	Aortic Valve Prolapse	5.7%
439	Cholestasis, Extrahepatic	5.7%
440	Biliary Dyskinesia	5.7%
441	Cholangitis, Sclerosing	5.7%
442	Colonic Diseases, Functional	5.7%
443	Esophageal motility disorders	5.7%
444	Fecal Incontinence	5.7%
445	Fecal Impaction	5.7%
446	Intussusception	5.7%
447	Mallory-Weiss Syndrome	5.7%
448	Megacolon	5.7%
449	Pyloric Stenosis	5.7%
450	Tricuspid Valve Prolapse	5.7%
451	Acalculous Cholecystitis	5.7%
452	Ileus	5.7%
453	Takotsubo Cardiomyopathy	5.7%
454	Meconium ileus	5.7%
455	Hematoma, Subdural	5.5%
456	Hematoma, Epidural, Cranial	5.5%
457	Romano-Ward Syndrome	5.5%
458	Esophageal Perforation	5.5%
459	Intestinal Diseases, Parasitic	5.5%
460	Barrett Esophagus	5.3%
461	Deglutition Disorders	5.3%
462	Subacute Bacterial Endocarditis	5.3%
463	Hematoma, Subdural, Intracranial	5.2%
464	Hematoma, Subdural, Chronic	5.2%
465	Hematoma, Subdural, Acute	5.2%
466	Achlorhydria	5.2%
467	Sinus Arrhythmia	5.2%
468	Atrial Fibrillation	5.2%
469	Atrial Flutter	5.2%
470	Edema, Cardiac	5.2%
471	Pancreatic Pseudocyst	5.2%
472	Ventricular Fibrillation	5.2%
473	Ventricular Flutter	5.2%
474	Parasystole	5.2%
475	Paroxysmal atrial fibrillation	5.2%
476	Bradycardia	5.2%
477	Diabetic Cardiomyopathies	5.2%
478	Esophageal Achalasia	5.1%
479	Anal Fissure	5.1%
480	Intestinal Pseudo-Obstruction	5.1%
481	Irritable Bowel Syndrome	5.1%
482	Superior Mesenteric Artery Syndrome	5.1%
483	Emphysematous Cholecystitis	5.1%
484	Neurogenic Bowel	5.1%
485	Sphincter of Oddi Dysfunction	5.1%
486	Anal Ulcer	5.1%
487	Cardiomyopathy, Alcoholic	5.1%
488	Ectopia Cordis	5.1%
489	Peptic Ulcer Hemorrhage	5.1%
490	Sudden Cardiac Death	5.1%
491	Left Ventricular Hypertrophy	5.1%
492	Gastroparesis	5.1%
493	Right Ventricular Hypertrophy	5.1%
494	Pancreatitis, Alcoholic	5.1%
495	Single umbilical artery	5.1%
496	Chagas Cardiomyopathy	5.1%
497	Noonan Syndrome	5.1%
498	Brain Hemorrhage, Traumatic	4.9%
499	Cystic Fibrosis	4.8%
500	Congenital Hyperinsulinism	4.6%
501	Marfan Syndrome	4.6%
502	Carcinoid Heart Disease	4.5%
503	MELAS Syndrome	4.5%
504	Carcinoma, Pancreatic Ductal	4.4%
505	Afferent Loop Syndrome	4.3%
506	Celiac Disease	4.3%
507	Short Bowel Syndrome	4.3%
508	Sprue, Tropical	4.3%
509	Steatorrhea	4.3%
510	Rectocele	4.3%
511	Sprue	4.3%
512	Diverticulitis	4.2%
513	Dumping Syndrome	4.2%
514	Rectal Prolapse	4.2%
515	Sinus Arrest, Cardiac	4.2%
516	Melena	4.1%
517	insulinoma	4.1%
518	Gastrinoma	4.1%
519	Glucagonoma	4.1%
520	Dyspnea, Paroxysmal	4.1%
521	Hematemesis	4.1%
522	Pruritus Ani	3.8%
523	Laryngopharyngeal Reflux	3.7%
524	Vipoma	3.6%
525	Giardiasis	3.5%
526	Fabry Disease	3.5%
527	Dural Arteriovenous Fistula	3.4%
528	Diverticulum	3.4%
529	Diverticulosis	3.4%
530	Nesidioblastosis	3.4%
531	Peutz-Jeghers Syndrome	2.8%
532	Lactose Intolerance	2.8%
533	Turner Syndrome	2.6%
534	Williams Syndrome	2.5%
535	Kartagener Syndrome	2.4%
536	Cryptosporidiosis	2.1%
537	Kearns-Sayre syndrome	1.6%

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